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These shares were sold in multiple transactions at prices ranging from $28.00 to\n$28.925 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and\nExchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote."}],"balance_after":38821,"source":{"system":"sec-edgar","filing":"0001209191-21-021150","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1776881/000120919121021150/doc4.xml","form_type":"4"}},{"id":2921205,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":89129,"kind":"person","name":"Keen Nicholas","position":1,"cik":"0001776881","reported_name":"Keen Nicholas","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Scientific Officer"}}],"security":"Employee Stock Option (right to buy)","published_at":"2021-01-05T17:36:35.000Z","date":"2021-01-04","kind":"grant","acquired":true,"shares":70500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option shall vest one-fourth (1/4) of the total number of shares under option on January 4, 2022 and the remaining shares in 36 equal monthly installments thereafter."}],"balance_after":70500,"derivative":{"exercise_price":17.95,"expiration_date":"2031-01-04","underlying":"Common Stock","underlying_shares":70500},"source":{"system":"sec-edgar","filing":"0001209191-21-001372","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1776881/000120919121001372/doc4.xml","form_type":"4"}},{"id":3169151,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":89129,"kind":"person","name":"Keen Nicholas","position":1,"cik":"0001776881","reported_name":"Keen Nicholas","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Scientific Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2020-04-27T16:44:48.000Z","date":"2019-06-28","kind":"grant","acquired":true,"shares":177404,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"date","element":"transactionDate","label":"F1","text":"The original Form 4 inadvertently listed the incorrect date of earliest transaction, transaction date and expiration date. This Form 4 amendment is being filed to accurately reflect the appropriates dates."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This option shall vest in 36 equal monthly installments at the end of each calendar month following the date of the grant."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"The original Form 4 inadvertently listed the incorrect date of earliest transaction, transaction date and expiration date. This Form 4 amendment is being filed to accurately reflect the appropriates dates."}],"balance_after":177404,"derivative":{"exercise_price":14,"expiration_date":"2029-06-28","underlying":"Ordinary Shares","underlying_shares":177404},"source":{"system":"sec-edgar","filing":"0001209191-20-025811","document":"doc4a.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1776881/000120919120025811/doc4a.xml","form_type":"4/A","original_submission_date":"2019-05-30"}},{"id":3318722,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":89129,"kind":"person","name":"Keen Nicholas","position":1,"cik":"0001776881","reported_name":"Keen Nicholas","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Scientific Officer"}}],"security":"Employee Stock Option (right to buy)","published_at":"2020-01-06T16:59:44.000Z","date":"2020-01-02","kind":"grant","acquired":true,"shares":60000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option shall vest one-fourth (1/4) of the total number of shares under option on January 2, 2021 and the remaining shares in 36 equal monthly installments at the end of each calendar month therafter."}],"balance_after":60000,"derivative":{"exercise_price":9.82,"expiration_date":"2030-01-02","underlying":"Ordinary Shares","underlying_shares":60000},"source":{"system":"sec-edgar","filing":"0001209191-20-001944","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1776881/000120919120001944/doc4.xml","form_type":"4"}},{"id":3507676,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":89129,"kind":"person","name":"Keen Nicholas","position":1,"cik":"0001776881","reported_name":"Keen Nicholas","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Scientific Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2019-05-30T21:24:10.000Z","date":"2019-05-28","kind":"grant","acquired":true,"shares":177404,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option shall vest in 36 equal monthly installments at the end of each calendar month following the date of the grant."}],"balance_after":177404,"derivative":{"exercise_price":14,"expiration_date":"2029-05-28","underlying":"Ordinary Shares","underlying_shares":177404},"source":{"system":"sec-edgar","filing":"0001104659-19-032907","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1776881/000110465919032907/a4.xml","form_type":"4"}}]}