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Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes."}],"balance_after":7299751,"source":{"system":"sec-edgar","filing":"0001062993-21-001115","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1164426/000106299321001115/form4.xml","form_type":"4"}},{"id":2872421,"issuer":{"id":90644,"kind":"organization","name":"Landos Biopharma, Inc.","symbol":"LABP"},"owners":[{"id":19219,"kind":"person","name":"PERCEPTIVE ADVISORS LLC","position":1,"cik":"0001224962","reported_name":"PERCEPTIVE ADVISORS LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19221,"kind":"person","name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","position":2,"cik":"0001249675","reported_name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":135874,"kind":"person","name":"Xontogeny, LLC","position":3,"cik":"0001844296","reported_name":"Xontogeny, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":82935,"kind":"person","name":"Perceptive Xontogeny Venture Fund, LP","position":4,"cik":"0001757940","reported_name":"Perceptive Xontogeny Venture Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19220,"kind":"person","name":"EDELMAN JOSEPH","position":5,"cik":"0001164426","reported_name":"EDELMAN JOSEPH","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-02-10T00:20:20.000Z","date":"2021-02-09","kind":"purchase","acquired":true,"shares":64730,"price":13.8,"value":893274.0,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The prices reported in Column 4 are weighted average prices. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges of the prices reported on this Form 4."},{"field":"price","element":"transactionPricePerShare","label":"F6","text":"These shares were purchased in multiple transactions at prices ranging from $13.17 to $14.16, inclusive."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F8","text":"The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the \"Master Fund\").  Perceptive Advisors LLC (the ???Advisor\") serves as the investment manager of Master Fund.  Joseph Edelman is the managing member of the Advisor.  Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes."}],"balance_after":7264800,"source":{"system":"sec-edgar","filing":"0001062993-21-001115","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1164426/000106299321001115/form4.xml","form_type":"4"}},{"id":2872420,"issuer":{"id":90644,"kind":"organization","name":"Landos Biopharma, Inc.","symbol":"LABP"},"owners":[{"id":19219,"kind":"person","name":"PERCEPTIVE ADVISORS LLC","position":1,"cik":"0001224962","reported_name":"PERCEPTIVE ADVISORS LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19221,"kind":"person","name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","position":2,"cik":"0001249675","reported_name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":135874,"kind":"person","name":"Xontogeny, LLC","position":3,"cik":"0001844296","reported_name":"Xontogeny, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":82935,"kind":"person","name":"Perceptive Xontogeny Venture Fund, LP","position":4,"cik":"0001757940","reported_name":"Perceptive Xontogeny Venture Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19220,"kind":"person","name":"EDELMAN JOSEPH","position":5,"cik":"0001164426","reported_name":"EDELMAN JOSEPH","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-02-10T00:20:20.000Z","date":"2021-02-08","kind":"purchase","acquired":true,"shares":1771,"price":13.1,"value":23200.1,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The prices reported in Column 4 are weighted average prices. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges of the prices reported on this Form 4."},{"field":"price","element":"transactionPricePerShare","label":"F5","text":"These shares were purchased in multiple transactions at prices ranging from $13.09 to $13.10, inclusive."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F8","text":"The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the \"Master Fund\").  Perceptive Advisors LLC (the ???Advisor\") serves as the investment manager of Master Fund.  Joseph Edelman is the managing member of the Advisor.  Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes."}],"balance_after":7200070,"source":{"system":"sec-edgar","filing":"0001062993-21-001115","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1164426/000106299321001115/form4.xml","form_type":"4"}},{"id":2872419,"issuer":{"id":90644,"kind":"organization","name":"Landos Biopharma, Inc.","symbol":"LABP"},"owners":[{"id":19219,"kind":"person","name":"PERCEPTIVE ADVISORS LLC","position":1,"cik":"0001224962","reported_name":"PERCEPTIVE ADVISORS LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19221,"kind":"person","name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","position":2,"cik":"0001249675","reported_name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":135874,"kind":"person","name":"Xontogeny, LLC","position":3,"cik":"0001844296","reported_name":"Xontogeny, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":82935,"kind":"person","name":"Perceptive Xontogeny Venture Fund, LP","position":4,"cik":"0001757940","reported_name":"Perceptive Xontogeny Venture Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19220,"kind":"person","name":"EDELMAN JOSEPH","position":5,"cik":"0001164426","reported_name":"EDELMAN JOSEPH","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-02-10T00:20:20.000Z","date":"2021-02-08","kind":"purchase","acquired":true,"shares":86671,"price":12.53,"value":1085987.63,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The prices reported in Column 4 are weighted average prices. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges of the prices reported on this Form 4."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"These shares were purchased in multiple transactions at prices ranging from $11.96 to $12.95, inclusive."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F8","text":"The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the \"Master Fund\").  Perceptive Advisors LLC (the ???Advisor\") serves as the investment manager of Master Fund.  Joseph Edelman is the managing member of the Advisor.  Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes."}],"balance_after":7198299,"source":{"system":"sec-edgar","filing":"0001062993-21-001115","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1164426/000106299321001115/form4.xml","form_type":"4"}},{"id":2872418,"issuer":{"id":90644,"kind":"organization","name":"Landos Biopharma, Inc.","symbol":"LABP"},"owners":[{"id":19219,"kind":"person","name":"PERCEPTIVE ADVISORS LLC","position":1,"cik":"0001224962","reported_name":"PERCEPTIVE ADVISORS LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19221,"kind":"person","name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","position":2,"cik":"0001249675","reported_name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":135874,"kind":"person","name":"Xontogeny, LLC","position":3,"cik":"0001844296","reported_name":"Xontogeny, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":82935,"kind":"person","name":"Perceptive Xontogeny Venture Fund, LP","position":4,"cik":"0001757940","reported_name":"Perceptive Xontogeny Venture Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19220,"kind":"person","name":"EDELMAN JOSEPH","position":5,"cik":"0001164426","reported_name":"EDELMAN JOSEPH","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-02-10T00:20:20.000Z","date":"2021-02-08","kind":"purchase","acquired":true,"shares":34611,"price":11.38,"value":393873.18,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The prices reported in Column 4 are weighted average prices. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges of the prices reported on this Form 4."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"These shares were purchased in multiple transactions at prices ranging from $10.96 to $11.93, inclusive."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F8","text":"The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the \"Master Fund\").  Perceptive Advisors LLC (the ???Advisor\") serves as the investment manager of Master Fund.  Joseph Edelman is the managing member of the Advisor.  Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes."}],"balance_after":7111628,"source":{"system":"sec-edgar","filing":"0001062993-21-001115","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1164426/000106299321001115/form4.xml","form_type":"4"}},{"id":2872417,"issuer":{"id":90644,"kind":"organization","name":"Landos Biopharma, Inc.","symbol":"LABP"},"owners":[{"id":19219,"kind":"person","name":"PERCEPTIVE ADVISORS LLC","position":1,"cik":"0001224962","reported_name":"PERCEPTIVE ADVISORS LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19221,"kind":"person","name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","position":2,"cik":"0001249675","reported_name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":135874,"kind":"person","name":"Xontogeny, LLC","position":3,"cik":"0001844296","reported_name":"Xontogeny, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":82935,"kind":"person","name":"Perceptive Xontogeny Venture Fund, LP","position":4,"cik":"0001757940","reported_name":"Perceptive Xontogeny Venture Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19220,"kind":"person","name":"EDELMAN JOSEPH","position":5,"cik":"0001164426","reported_name":"EDELMAN JOSEPH","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-02-10T00:20:20.000Z","date":"2021-02-05","kind":"purchase","acquired":true,"shares":27453,"price":11.14,"value":305826.42,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The prices reported in Column 4 are weighted average prices. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges of the prices reported on this Form 4."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"These shares were purchased in multiple transactions at prices ranging from $11.05 to $11.75, inclusive."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F8","text":"The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the \"Master Fund\").  Perceptive Advisors LLC (the ???Advisor\") serves as the investment manager of Master Fund.  Joseph Edelman is the managing member of the Advisor.  Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes."}],"balance_after":7077017,"source":{"system":"sec-edgar","filing":"0001062993-21-001115","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1164426/000106299321001115/form4.xml","form_type":"4"}},{"id":2874804,"issuer":{"id":90644,"kind":"organization","name":"Landos Biopharma, Inc.","symbol":"LABP"},"owners":[{"id":19219,"kind":"person","name":"PERCEPTIVE ADVISORS LLC","position":1,"cik":"0001224962","reported_name":"PERCEPTIVE ADVISORS LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19221,"kind":"person","name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","position":2,"cik":"0001249675","reported_name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":135874,"kind":"person","name":"Xontogeny, LLC","position":3,"cik":"0001844296","reported_name":"Xontogeny, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":82935,"kind":"person","name":"Perceptive Xontogeny Venture Fund, LP","position":4,"cik":"0001757940","reported_name":"Perceptive Xontogeny Venture Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19220,"kind":"person","name":"EDELMAN JOSEPH","position":5,"cik":"0001164426","reported_name":"EDELMAN JOSEPH","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series B Preferred Stock","published_at":"2021-02-08T23:37:38.000Z","date":"2021-02-08","kind":"exercise","acquired":false,"shares":1770600,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F2","text":"Each share of the Issuer's Series B preferred stock automatically converted into shares of the Issuer's common stock immediately upon the closing of the Issuer's initial public offering. The Series B preferred stock had no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"Each share of the Issuer's Series B preferred stock automatically converted into shares of the Issuer's common stock immediately upon the closing of the Issuer's initial public offering. The Series B preferred stock had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"Each share of the Issuer's Series B preferred stock automatically converted into shares of the Issuer's common stock immediately upon the closing of the Issuer's initial public offering. The Series B preferred stock had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F2","text":"Each share of the Issuer's Series B preferred stock automatically converted into shares of the Issuer's common stock immediately upon the closing of the Issuer's initial public offering. 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The Advisor, PXV GP and Mr. Edelman disclaim, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his or its indirect pecuniary interest therein, and this report shall not be deemed an admission that they are the beneficial owner of such securities for purposes of Section 16 or for any other purposes."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":1770600},"source":{"system":"sec-edgar","filing":"0001062993-21-001012","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":12,"url":"https://www.sec.gov/Archives/edgar/data/1164426/000106299321001012/form4.xml","form_type":"4"}},{"id":2874803,"issuer":{"id":90644,"kind":"organization","name":"Landos Biopharma, Inc.","symbol":"LABP"},"owners":[{"id":19219,"kind":"person","name":"PERCEPTIVE ADVISORS LLC","position":1,"cik":"0001224962","reported_name":"PERCEPTIVE ADVISORS LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19221,"kind":"person","name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","position":2,"cik":"0001249675","reported_name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":135874,"kind":"person","name":"Xontogeny, LLC","position":3,"cik":"0001844296","reported_name":"Xontogeny, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":82935,"kind":"person","name":"Perceptive Xontogeny Venture Fund, LP","position":4,"cik":"0001757940","reported_name":"Perceptive Xontogeny Venture Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19220,"kind":"person","name":"EDELMAN JOSEPH","position":5,"cik":"0001164426","reported_name":"EDELMAN JOSEPH","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series B Preferred Stock","published_at":"2021-02-08T23:37:38.000Z","date":"2021-02-08","kind":"exercise","acquired":false,"shares":2857795,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F2","text":"Each share of the Issuer's Series B preferred stock automatically converted into shares of the Issuer's common stock immediately upon the closing of the Issuer's initial public offering. The Series B preferred stock had no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"Each share of the Issuer's Series B preferred stock automatically converted into shares of the Issuer's common stock immediately upon the closing of the Issuer's initial public offering. The Series B preferred stock had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"Each share of the Issuer's Series B preferred stock automatically converted into shares of the Issuer's common stock immediately upon the closing of the Issuer's initial public offering. The Series B preferred stock had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F2","text":"Each share of the Issuer's Series B preferred stock automatically converted into shares of the Issuer's common stock immediately upon the closing of the Issuer's initial public offering. 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Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes."}],"balance_after":2941769,"source":{"system":"sec-edgar","filing":"0001062993-21-001012","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1164426/000106299321001012/form4.xml","form_type":"4"}},{"id":2882430,"issuer":{"id":68888,"kind":"organization","name":"Astria Therapeutics, Inc.","symbol":"ATXS"},"owners":[{"id":19219,"kind":"person","name":"PERCEPTIVE ADVISORS LLC","position":1,"cik":"0001224962","reported_name":"PERCEPTIVE ADVISORS LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19221,"kind":"person","name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","position":2,"cik":"0001249675","reported_name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":135874,"kind":"person","name":"Xontogeny, LLC","position":3,"cik":"0001844296","reported_name":"Xontogeny, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":82935,"kind":"person","name":"Perceptive Xontogeny Venture Fund, LP","position":4,"cik":"0001757940","reported_name":"Perceptive Xontogeny Venture Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19220,"kind":"person","name":"EDELMAN JOSEPH","position":5,"cik":"0001164426","reported_name":"EDELMAN JOSEPH","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series X Convertible Preferred Stock","published_at":"2021-02-04T00:15:11.000Z","date":"2021-02-01","kind":"grant","acquired":true,"shares":1617,"price":3009.53,"value":4866410.01,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Upon stockholder approval of the conversion of Series X Convertible Preferred Stock into shares of common stock, each share of Series X Non-Voting Convertible Preferred Stock automatically converts into 1,000 shares of Common Stock, subject to certain limitations."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Upon stockholder approval of the conversion of Series X Convertible Preferred Stock into shares of common stock, each share of Series X Non-Voting Convertible Preferred Stock automatically converts into 1,000 shares of Common Stock, subject to certain limitations."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Upon stockholder approval of the conversion of Series X Convertible Preferred Stock into shares of common stock, each share of Series X Non-Voting Convertible Preferred Stock automatically converts into 1,000 shares of Common Stock, subject to certain limitations."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"3.\tThe securities are directly held by Perceptive Xontogeny Ventures, L.P. (\"PXV\").  The Advisor serves as the investment manager of PXV, and Perceptive Xontogeny Ventures GP, LLC (\"PXV GP\") is the general partner of PXV. Mr. Edelman is the managing member of PXV GP and the Advisor. The Advisor, PXV GP and Mr. Edelman disclaim, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his or its indirect pecuniary interest therein, and this report shall not be deemed an admission that they are the beneficial owner of such securities for purposes of Section 16 or for any other purposes."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The securities reported herein were purchased from the Issuer pursuant to a Securities Purchase Agreement."}],"balance_after":30920,"derivative":{"underlying":"Common Stock","underlying_shares":1617000},"source":{"system":"sec-edgar","filing":"0001062993-21-000859","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1164426/000106299321000859/form4.xml","form_type":"4"}},{"id":2882429,"issuer":{"id":68888,"kind":"organization","name":"Astria Therapeutics, Inc.","symbol":"ATXS"},"owners":[{"id":19219,"kind":"person","name":"PERCEPTIVE ADVISORS LLC","position":1,"cik":"0001224962","reported_name":"PERCEPTIVE ADVISORS LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19221,"kind":"person","name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","position":2,"cik":"0001249675","reported_name":"PERCEPTIVE LIFE SCIENCES MASTER FUND LTD","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":135874,"kind":"person","name":"Xontogeny, LLC","position":3,"cik":"0001844296","reported_name":"Xontogeny, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":82935,"kind":"person","name":"Perceptive Xontogeny Venture Fund, LP","position":4,"cik":"0001757940","reported_name":"Perceptive Xontogeny Venture Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":19220,"kind":"person","name":"EDELMAN JOSEPH","position":5,"cik":"0001164426","reported_name":"EDELMAN JOSEPH","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series X Convertible Preferred Stock","published_at":"2021-02-04T00:15:11.000Z","date":"2021-02-01","kind":"grant","acquired":true,"shares":4851,"price":3009.53,"value":14599230.03,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Upon stockholder approval of the conversion of Series X Convertible Preferred Stock into shares of common stock, each share of Series X Non-Voting Convertible Preferred Stock automatically converts into 1,000 shares of Common Stock, subject to certain limitations."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Upon stockholder approval of the conversion of Series X Convertible Preferred Stock into shares of common stock, each share of Series X Non-Voting Convertible Preferred Stock automatically converts into 1,000 shares of Common Stock, subject to certain limitations."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Upon stockholder approval of the conversion of Series X Convertible Preferred Stock into shares of common stock, each share of Series X Non-Voting Convertible Preferred Stock automatically converts into 1,000 shares of Common Stock, subject to certain limitations."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are directly held by Perceptive Life Sciences Master Fund Ltd. (the \"Master Fund\").  Perceptive Advisors LLC (the \"Advisor\") serves as the investment manager of Master Fund.  Joseph Edelman is the managing member of the Advisor.  Each of Mr. Edelman and the Advisor disclaims, for purposes of Section 16 of the Securities Exchange Act of 1934, beneficial ownership of such securities, except to the extent of his/its indirect pecuniary interest therein, and this report shall not be deemed an admission that either Mr. Edelman or the Advisor is the beneficial owner of such securities for purposes of Section 16 or for any other purposes."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The securities reported herein were purchased from the Issuer pursuant to a Securities Purchase Agreement."}],"balance_after":4851,"derivative":{"underlying":"Common Stock","underlying_shares":4851000},"source":{"system":"sec-edgar","filing":"0001062993-21-000859","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1164426/000106299321000859/form4.xml","form_type":"4"}}]}