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25% of the total number of shares subject to the option on February 25, 2021, and vest and become exercisable with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":45000,"derivative":{"exercise_price":12.15,"expiration_date":"2030-02-25","underlying":"Ordinary Shares","underlying_shares":5000},"source":{"system":"sec-edgar","filing":"0000905148-23-001091","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000090514823001091/form4.xml","form_type":"4"}},{"id":1765348,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol 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pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 7, 2023."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $45.86 to $46.78, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the ranges set forth in footnotes 2 through 3 of this Form 4."}],"balance_after":663,"source":{"system":"sec-edgar","filing":"0000905148-23-001091","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000090514823001091/form4.xml","form_type":"4"}},{"id":1765346,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-10-04T19:52:41.000Z","date":"2023-10-04","kind":"exercise","planned":true,"acquired":true,"shares":5000,"price":12.15,"value":60750.0,"ownership":{"direct":true},"balance_after":5000,"source":{"system":"sec-edgar","filing":"0000905148-23-001091","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000090514823001091/form4.xml","form_type":"4"}},{"id":1787214,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2023-09-06T19:42:06.000Z","date":"2023-09-06","kind":"exercise","planned":true,"acquired":false,"shares":5000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The shares subject to the option vested and became exercisable as to 25% of the total number of shares subject to the option on February 25, 2021, and vest and become exercisable with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":50000,"derivative":{"exercise_price":12.15,"expiration_date":"2030-02-25","underlying":"Ordinary Shares","underlying_shares":5000},"source":{"system":"sec-edgar","filing":"0000905148-23-000853","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000090514823000853/form4.xml","form_type":"4"}},{"id":1787213,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-09-06T19:42:06.000Z","date":"2023-09-06","kind":"sale","planned":true,"acquired":false,"shares":6,"price":55.27,"value":331.62,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 7, 2023."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0000905148-23-000853","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000090514823000853/form4.xml","form_type":"4"}},{"id":1787212,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-09-06T19:42:06.000Z","date":"2023-09-06","kind":"sale","planned":true,"acquired":false,"shares":4994,"price":54.7601,"value":273471.9394,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 7, 2023."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"This transaction was executed in multiple trades in prices ranging from $54.23 to $55.20, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in footnote 2 of this Form 4."}],"balance_after":6,"source":{"system":"sec-edgar","filing":"0000905148-23-000853","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000090514823000853/form4.xml","form_type":"4"}},{"id":1787211,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per 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a Rule 10b5-1 trading plan adopted by the Reporting Person on March 7, 2023."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $67.63 to $68.61, inclusive."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001140361-23-037712","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036123037712/form4.xml","form_type":"4"}},{"id":1817933,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per 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The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the ranges set forth in footnotes 2 through 3 of this Form 4."}],"balance_after":328,"source":{"system":"sec-edgar","filing":"0001140361-23-037712","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036123037712/form4.xml","form_type":"4"}},{"id":1817932,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per 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to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 7, 2023."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $68.44 to $68.99, inclusive."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001140361-23-033193","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036123033193/form4.xml","form_type":"4"}},{"id":1836316,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per 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The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the ranges set forth in footnotes 2 through 3 of this Form 4."}],"balance_after":1034,"source":{"system":"sec-edgar","filing":"0001140361-23-033193","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036123033193/form4.xml","form_type":"4"}},{"id":1836315,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per 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25% of the total number of shares subject to the option on February 25, 2021, and vest and become exercisable with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":65000,"derivative":{"exercise_price":12.15,"expiration_date":"2030-02-25","underlying":"Ordinary Shares","underlying_shares":5000},"source":{"system":"sec-edgar","filing":"0001140361-23-028869","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036123028869/form4.xml","form_type":"4"}},{"id":1863936,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol 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inclusive."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001140361-23-028869","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036123028869/form4.xml","form_type":"4"}},{"id":1863935,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-06-07T21:49:31.000Z","date":"2023-06-07","kind":"sale","planned":true,"acquired":false,"shares":3811,"price":71.9682,"value":274270.8102,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 7, 2023."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The transaction was executed in multiple trades in prices ranging from $71.53 to $72.41, inclusive."}],"balance_after":361,"source":{"system":"sec-edgar","filing":"0001140361-23-028869","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036123028869/form4.xml","form_type":"4"}},{"id":1863934,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-06-07T21:49:31.000Z","date":"2023-06-07","kind":"sale","planned":true,"acquired":false,"shares":12782,"price":70.9979,"value":907495.1578,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 7, 2023."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $70.53 to $71.51, inclusive."}],"balance_after":4172,"source":{"system":"sec-edgar","filing":"0001140361-23-028869","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036123028869/form4.xml","form_type":"4"}},{"id":1863933,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD 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The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the ranges set forth in footnotes 2 through 5 of this Form 4."}],"balance_after":16954,"source":{"system":"sec-edgar","filing":"0001140361-23-028869","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036123028869/form4.xml","form_type":"4"}},{"id":1863932,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per 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share","published_at":"2023-06-07T21:49:31.000Z","date":"2023-06-07","kind":"exercise","planned":true,"acquired":true,"shares":5000,"price":12.15,"value":60750.0,"ownership":{"direct":true},"balance_after":5000,"source":{"system":"sec-edgar","filing":"0001140361-23-028869","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036123028869/form4.xml","form_type":"4"}},{"id":1973792,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2023-03-03T21:31:10.000Z","date":"2023-03-02","kind":"grant","acquired":true,"shares":48000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 2, 2024 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":48000,"derivative":{"exercise_price":52.97,"expiration_date":"2033-03-02","underlying":"Ordinary Shares","underlying_shares":48000},"source":{"system":"sec-edgar","filing":"0001140361-23-010186","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036123010186/form4.xml","form_type":"4"}},{"id":2372165,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2022-02-25T21:32:15.000Z","date":"2022-02-23","kind":"grant","acquired":true,"shares":85000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 23, 2023 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":85000,"derivative":{"exercise_price":32.45,"expiration_date":"2032-02-23","underlying":"Ordinary Shares","underlying_shares":85000},"source":{"system":"sec-edgar","filing":"0001140361-22-006899","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036122006899/form4.xml","form_type":"4"}},{"id":2526395,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol 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Shares","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001567619-21-019301","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000156761921019301/doc1.xml","form_type":"4"}},{"id":2526394,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-11-03T21:17:18.000Z","date":"2021-11-01","kind":"sale","acquired":false,"shares":4937,"price":58.508,"value":288853.996,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The transaction was executed in multiple trades in prices ranging from $58.14 to $58.76, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001567619-21-019301","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000156761921019301/doc1.xml","form_type":"4"}},{"id":2526393,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-11-03T21:17:18.000Z","date":"2021-11-01","kind":"sale","acquired":false,"shares":2725,"price":56.6529,"value":154379.1525,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $56.185 to $56.89, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":4937,"source":{"system":"sec-edgar","filing":"0001567619-21-019301","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000156761921019301/doc1.xml","form_type":"4"}},{"id":2526392,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-11-03T21:17:18.000Z","date":"2021-11-01","kind":"sale","acquired":false,"shares":2338,"price":54.998,"value":128585.324,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $54.92 to $55.16, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":7662,"source":{"system":"sec-edgar","filing":"0001567619-21-019301","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000156761921019301/doc1.xml","form_type":"4"}},{"id":2526391,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-11-03T21:17:18.000Z","date":"2021-11-01","kind":"exercise","acquired":true,"shares":10000,"price":15.04,"value":150400.0,"ownership":{"direct":true},"balance_after":10000,"source":{"system":"sec-edgar","filing":"0001567619-21-019301","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000156761921019301/doc1.xml","form_type":"4"}},{"id":2554453,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2021-10-01T20:46:58.000Z","date":"2021-10-01","kind":"exercise","acquired":false,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on June 21, 2019 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":130000,"derivative":{"exercise_price":15.04,"expiration_date":"2028-06-21","underlying":"Ordinary Shares","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001140361-21-033345","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036121033345/form4.xml","form_type":"4"}},{"id":2554452,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-10-01T20:46:58.000Z","date":"2021-10-01","kind":"sale","acquired":false,"shares":213,"price":70.44,"value":15003.72,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001140361-21-033345","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036121033345/form4.xml","form_type":"4"}},{"id":2554451,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-10-01T20:46:58.000Z","date":"2021-10-01","kind":"sale","acquired":false,"shares":2600,"price":69.6142,"value":180996.92,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F5","text":"The transaction was executed in multiple trades in prices ranging from $69.33 to $70.115, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":213,"source":{"system":"sec-edgar","filing":"0001140361-21-033345","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036121033345/form4.xml","form_type":"4"}},{"id":2554450,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-10-01T20:46:58.000Z","date":"2021-10-01","kind":"sale","acquired":false,"shares":1967,"price":68.6756,"value":135084.9052,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The transaction was executed in multiple trades in prices ranging from $68.33 to $69.13, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":2813,"source":{"system":"sec-edgar","filing":"0001140361-21-033345","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036121033345/form4.xml","form_type":"4"}},{"id":2554449,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-10-01T20:46:58.000Z","date":"2021-10-01","kind":"sale","acquired":false,"shares":2620,"price":67.9763,"value":178097.906,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $67.33 to $68.30, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":4780,"source":{"system":"sec-edgar","filing":"0001140361-21-033345","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036121033345/form4.xml","form_type":"4"}},{"id":2554448,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-10-01T20:46:58.000Z","date":"2021-10-01","kind":"sale","acquired":false,"shares":2600,"price":66.5971,"value":173152.46,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $66.29 to $67.035, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":7400,"source":{"system":"sec-edgar","filing":"0001140361-21-033345","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036121033345/form4.xml","form_type":"4"}},{"id":2554447,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-10-01T20:46:58.000Z","date":"2021-10-01","kind":"exercise","acquired":true,"shares":10000,"price":15.04,"value":150400.0,"ownership":{"direct":true},"balance_after":10000,"source":{"system":"sec-edgar","filing":"0001140361-21-033345","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036121033345/form4.xml","form_type":"4"}},{"id":2573241,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2021-09-10T17:06:07.000Z","date":"2021-09-09","kind":"exercise","acquired":false,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on June 21, 2019 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":140000,"derivative":{"exercise_price":15.04,"expiration_date":"2028-06-21","underlying":"Ordinary Shares","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001140361-21-030941","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036121030941/form4.xml","form_type":"4"}},{"id":2573240,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-09-10T17:06:07.000Z","date":"2021-09-09","kind":"sale","acquired":false,"shares":4542,"price":72.6299,"value":329885.0058,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $72.16 to $72.83, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001140361-21-030941","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036121030941/form4.xml","form_type":"4"}},{"id":2573239,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-09-10T17:06:07.000Z","date":"2021-09-09","kind":"sale","acquired":false,"shares":5458,"price":71.4477,"value":389961.5466,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $70.94 to $71.75, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":4542,"source":{"system":"sec-edgar","filing":"0001140361-21-030941","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036121030941/form4.xml","form_type":"4"}},{"id":2573238,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"officer":true,"officer_title":"Chief Regulatory Officer"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2021-09-10T17:06:07.000Z","date":"2021-09-09","kind":"exercise","acquired":true,"shares":10000,"price":15.04,"value":150400.0,"ownership":{"direct":true},"balance_after":10000,"source":{"system":"sec-edgar","filing":"0001140361-21-030941","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000114036121030941/form4.xml","form_type":"4"}},{"id":2829843,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Regulatory Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2021-02-26T17:10:28.000Z","date":"2021-02-25","kind":"grant","acquired":true,"shares":56000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 25, 2022 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":56000,"derivative":{"exercise_price":22.6,"expiration_date":"2031-02-25","underlying":"Ordinary Shares","underlying_shares":56000},"source":{"system":"sec-edgar","filing":"0001567619-21-005082","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000156761921005082/doc1.xml","form_type":"4"}},{"id":2854931,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Regulatory Officer"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2021-02-17T18:39:53.000Z","date":"2021-02-12","kind":"grant","acquired":true,"shares":45112,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F4","text":"On February 12, 2021, the issuer canceled, pursuant to the issuer's option exchange program, an option for 60,000 of the issuer's ordinary shares granted to the reporting person on February 21, 2018. In exchange, the reporting person received a replacement option, for 45,112 ordinary shares, having an exercise price of $22.85 per ordinary share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The shares subject to the option will vest and become exercisable as to 47/48 of the total number of shares subject to the option on the one year anniversary of the date of grant and with respect to 1/48 of the total number of shares subject to the option on February 21, 2022, subject to the reporting person's continued service with the issuer on each such vesting date."}],"balance_after":45112,"derivative":{"exercise_price":22.85,"expiration_date":"2028-02-21","underlying":"Ordinary Shares","underlying_shares":45112},"source":{"system":"sec-edgar","filing":"0001567619-21-004307","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000156761921004307/doc1.xml","form_type":"4"}},{"id":2854930,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Regulatory Officer"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2021-02-17T18:39:53.000Z","date":"2021-02-12","kind":"disposition_to_issuer","acquired":false,"shares":60000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F4","text":"On February 12, 2021, the issuer canceled, pursuant to the issuer's option exchange program, an option for 60,000 of the issuer's ordinary shares granted to the reporting person on February 21, 2018. In exchange, the reporting person received a replacement option, for 45,112 ordinary shares, having an exercise price of $22.85 per ordinary share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 21, 2019 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the reporting person's continued employment with the issuer on each such vesting date."}],"balance_after":0,"derivative":{"exercise_price":33.1,"expiration_date":"2028-02-21","underlying":"Ordinary Shares","underlying_shares":60000},"source":{"system":"sec-edgar","filing":"0001567619-21-004307","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000156761921004307/doc1.xml","form_type":"4"}},{"id":2854929,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Regulatory Officer"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2021-02-17T18:39:53.000Z","date":"2021-02-12","kind":"grant","acquired":true,"shares":51282,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On February 12, 2021, the issuer canceled, pursuant to the issuer's option exchange program, an option for 100,000 of the issuer's ordinary shares granted to the reporting person on December 14, 2016. In exchange, the reporting person received a replacement option, for 51,282 ordinary shares, having an exercise price of $22.85 per ordinary share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary."}],"balance_after":51282,"derivative":{"exercise_price":22.85,"expiration_date":"2026-12-14","underlying":"Ordinary Shares","underlying_shares":51282},"source":{"system":"sec-edgar","filing":"0001567619-21-004307","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000156761921004307/doc1.xml","form_type":"4"}},{"id":2854928,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Regulatory Officer"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2021-02-17T18:39:53.000Z","date":"2021-02-12","kind":"disposition_to_issuer","acquired":false,"shares":100000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On February 12, 2021, the issuer canceled, pursuant to the issuer's option exchange program, an option for 100,000 of the issuer's ordinary shares granted to the reporting person on December 14, 2016. In exchange, the reporting person received a replacement option, for 51,282 ordinary shares, having an exercise price of $22.85 per ordinary share."}],"balance_after":0,"derivative":{"exercise_price":52.78,"exercise_date":"2020-12-14","expiration_date":"2026-12-14","underlying":"Ordinary Shares","underlying_shares":100000},"source":{"system":"sec-edgar","filing":"0001567619-21-004307","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000156761921004307/doc1.xml","form_type":"4"}},{"id":3243982,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol D.","position":1,"cik":"0001692214","reported_name":"Karp Carol D.","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Regulatory Officer"}}],"security":"Stock Option (Right to 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will vest and become exercisable as to 25% of the total number of shares subject to the option on February 27, 2020 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":50000,"derivative":{"exercise_price":13.53,"expiration_date":"2029-02-27","underlying":"Ordinary Shares","underlying_shares":50000},"source":{"system":"sec-edgar","filing":"0000899243-19-005426","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000089924319005426/doc4.xml","form_type":"4"}},{"id":3884140,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":82243,"kind":"person","name":"Karp Carol 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will vest and become exercisable as to 25% of the total number of shares subject to the option on December 14, 2017 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":100000,"derivative":{"exercise_price":52.78,"expiration_date":"2026-12-14","underlying":"Ordinary Shares","underlying_shares":100000},"source":{"system":"sec-edgar","filing":"0000899243-16-035768","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692214/000089924316035768/doc4.xml","form_type":"4"}}]}