{"transactions":[{"id":1131026,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-05-29T21:07:08.000Z","date":"2025-05-27","kind":"grant","planned":false,"acquired":true,"shares":500000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option will vest in four equal annual installments beginning May 27, 2026."}],"balance_after":500000,"derivative":{"exercise_price":1.31,"expiration_date":"2035-05-26","underlying":"Common Stock","underlying_shares":500000},"source":{"system":"sec-edgar","filing":"0000950170-25-079120","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000095017025079120/ownership.xml","form_type":"4"}},{"id":1448291,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2024-07-26T23:18:18.000Z","date":"2024-07-24","kind":"grant","planned":false,"acquired":true,"shares":500000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"Each restricted stock unit represents a contingent right to receive one share of OPKO common stock upon the vesting of the award. The\nrestricted stock units vest 50% on the second anniversary of the grant date, then 25% on each of the following two years."}],"balance_after":28499880,"source":{"system":"sec-edgar","filing":"0000950170-24-087039","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000095017024087039/ownership.xml","form_type":"4"}},{"id":1678432,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2024-01-17T22:09:48.000Z","date":"2024-01-17","kind":"purchase","planned":false,"acquired":true,"shares":150000,"price":0.95,"value":142500.0,"ownership":{"direct":true},"balance_after":27999880,"source":{"system":"sec-edgar","filing":"0000950170-24-005070","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000095017024005070/ownership.xml","form_type":"4"}},{"id":1684686,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"3.75% Convertible Notes due 2029","published_at":"2024-01-08T14:10:34.000Z","date":"2024-01-04","kind":"grant","planned":false,"acquired":true,"reported_value":6452000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The reporting person entered into a Convertible Note Purchase Agreement with OPKO Health, Inc. (the \"Issuer\") on January 4, 2024, pursuant to which the reporting person disposed of $5,000,000 aggregate principal amount of 5% Convertible Promissory Notes due 2025, and accrued and unpaid interest thereon, in exchange for $6,452,000  aggregate principal amount of the Issuer's 3.75% Convertible Senior Notes due 2029 in a private placement."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"Prior to September 15, 2028, holders of the 3.75% Convertible Senior Notes due 2029 will have the right to convert such notes only in certain circumstances and during specified periods and thereafter, will be convertible at the option of the holder at any time prior to the close of business on the business day immediately preceding January 15, 2029, the maturity date."}],"derivative":{"exercise_price":1.15,"exercise_date":"2028-09-15","expiration_date":"2029-01-15","underlying":"Common Stock"},"source":{"system":"sec-edgar","filing":"0000950170-24-002743","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/944809/000095017024002743/ownership.xml","form_type":"4"}},{"id":1684685,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"5% Convertible Notes due 2025","published_at":"2024-01-08T14:10:34.000Z","date":"2024-01-04","kind":"disposition_to_issuer","planned":false,"acquired":false,"reported_value":5000000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The 5% Convertible Promissory Notes due 2025 were originally entered into on February 27, 2018 and the Reporting Person had the option to convert all or any portion of the outstanding principal balance of such original notes, plus unpaid interest, into shares of the Issuer's (as defined below) common stock, par value $0.01 per share, at a conversion price of $5.00 per share, at any time prior to the maturity date, which was February 27, 2023. Pursuant to an amendment on February 10, 2023, the maturity date was extended to January 31, 2025, which amendment also reset the conversion price to the 10 day volume weighted average price immediately preceding the date of such amendment, plus a 25% conversion premium, or $1.66."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The 5% Convertible Promissory Notes due 2025 were originally entered into on February 27, 2018 and the Reporting Person had the option to convert all or any portion of the outstanding principal balance of such original notes, plus unpaid interest, into shares of the Issuer's (as defined below) common stock, par value $0.01 per share, at a conversion price of $5.00 per share, at any time prior to the maturity date, which was February 27, 2023. Pursuant to an amendment on February 10, 2023, the maturity date was extended to January 31, 2025, which amendment also reset the conversion price to the 10 day volume weighted average price immediately preceding the date of such amendment, plus a 25% conversion premium, or $1.66."}],"derivative":{"exercise_price":1.66,"expiration_date":"2025-01-31","underlying":"Common Stock"},"source":{"system":"sec-edgar","filing":"0000950170-24-002743","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/944809/000095017024002743/ownership.xml","form_type":"4"}},{"id":1684684,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2024-01-08T14:10:34.000Z","date":"2024-01-05","kind":"purchase","planned":false,"acquired":true,"shares":150010,"price":0.8726,"value":130898.726,"ownership":{"direct":true},"balance_after":27849880,"source":{"system":"sec-edgar","filing":"0000950170-24-002743","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000095017024002743/ownership.xml","form_type":"4"}},{"id":1744677,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2023-11-13T13:21:48.000Z","date":"2023-11-10","kind":"purchase","planned":false,"acquired":true,"shares":65942,"price":1.27,"value":83746.34,"ownership":{"direct":true},"balance_after":27699870,"source":{"system":"sec-edgar","filing":"0001209191-23-054918","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919123054918/doc4.xml","form_type":"4"}},{"id":1744676,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2023-11-13T13:21:48.000Z","date":"2023-11-10","kind":"purchase","planned":false,"acquired":true,"shares":34058,"price":1.26,"value":42913.08,"ownership":{"direct":true},"balance_after":27633928,"source":{"system":"sec-edgar","filing":"0001209191-23-054918","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919123054918/doc4.xml","form_type":"4"}},{"id":1885621,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Stock Option (Right to Buy)","published_at":"2023-05-19T20:39:45.000Z","date":"2023-05-18","kind":"grant","planned":false,"acquired":true,"shares":800000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option will vest in four equal annual installments beginning May 18, 2024."}],"balance_after":800000,"derivative":{"exercise_price":1.58,"expiration_date":"2033-05-17","underlying":"Common Stock","underlying_shares":800000},"source":{"system":"sec-edgar","filing":"0001209191-23-031036","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919123031036/doc4.xml","form_type":"4"}},{"id":2017557,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"5% Convertible Promissory Notes due 2025","published_at":"2023-02-14T23:06:01.000Z","date":"2023-02-10","kind":"grant","acquired":true,"price":5000000,"reported_value":5000000,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The two reported transactions involved an amendment and restatement of an outstanding convertible promissory note (the \"Original Note\"), resulting in the deemed cancellation of the Original Note and the execution of an amended note (the \"Amended Note\").  The Original Note was entered into on February 27, 2018 and the Reporting Person had the option to convert all or any portion of the outstanding principal balance of the Original Note, plus unpaid interest, into shares of the Issuer's common stock, par value $0.01 per share, at a conversion price of $5.00 per share, at any time prior to the maturity date, which was February 27, 2023.  The Amended Note extends the maturity to January 31, 2025, and resets the conversion price to the 10 day volume weighted average price immediately preceding the date of the Amended Note, plus a 25% conversion premium, or $1.66."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The two reported transactions involved an amendment and restatement of an outstanding convertible promissory note (the \"Original Note\"), resulting in the deemed cancellation of the Original Note and the execution of an amended note (the \"Amended Note\").  The Original Note was entered into on February 27, 2018 and the Reporting Person had the option to convert all or any portion of the outstanding principal balance of the Original Note, plus unpaid interest, into shares of the Issuer's common stock, par value $0.01 per share, at a conversion price of $5.00 per share, at any time prior to the maturity date, which was February 27, 2023.  The Amended Note extends the maturity to January 31, 2025, and resets the conversion price to the 10 day volume weighted average price immediately preceding the date of the Amended Note, plus a 25% conversion premium, or $1.66."}],"derivative":{"exercise_price":1.66,"expiration_date":"2025-01-31","underlying":"Common Stock"},"source":{"system":"sec-edgar","filing":"0001209191-23-009337","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919123009337/doc4.xml","form_type":"4"}},{"id":2017556,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"5% Convertible Promissory Notes due 2023","published_at":"2023-02-14T23:06:01.000Z","date":"2023-02-10","kind":"disposition_to_issuer","acquired":false,"price":5000000,"reported_value":5000000,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The two reported transactions involved an amendment and restatement of an outstanding convertible promissory note (the \"Original Note\"), resulting in the deemed cancellation of the Original Note and the execution of an amended note (the \"Amended Note\").  The Original Note was entered into on February 27, 2018 and the Reporting Person had the option to convert all or any portion of the outstanding principal balance of the Original Note, plus unpaid interest, into shares of the Issuer's common stock, par value $0.01 per share, at a conversion price of $5.00 per share, at any time prior to the maturity date, which was February 27, 2023.  The Amended Note extends the maturity to January 31, 2025, and resets the conversion price to the 10 day volume weighted average price immediately preceding the date of the Amended Note, plus a 25% conversion premium, or $1.66."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The two reported transactions involved an amendment and restatement of an outstanding convertible promissory note (the \"Original Note\"), resulting in the deemed cancellation of the Original Note and the execution of an amended note (the \"Amended Note\").  The Original Note was entered into on February 27, 2018 and the Reporting Person had the option to convert all or any portion of the outstanding principal balance of the Original Note, plus unpaid interest, into shares of the Issuer's common stock, par value $0.01 per share, at a conversion price of $5.00 per share, at any time prior to the maturity date, which was February 27, 2023.  The Amended Note extends the maturity to January 31, 2025, and resets the conversion price to the 10 day volume weighted average price immediately preceding the date of the Amended Note, plus a 25% conversion premium, or $1.66."}],"derivative":{"exercise_price":5,"expiration_date":"2023-02-27","underlying":"Common Stock"},"source":{"system":"sec-edgar","filing":"0001209191-23-009337","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919123009337/doc4.xml","form_type":"4"}},{"id":2609090,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2021-08-10T20:12:54.000Z","date":"2021-08-09","kind":"purchase","acquired":true,"shares":10,"price":3.73,"value":37.3,"ownership":{"direct":true},"footnotes":[{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"Includes 3,124,713 shares received as a pro rata distribution from The Frost Group, LLC (\"The Frost Group\"), of which the reporting person was a member. The Frost Group effected a pro rata distribution of its 20,091,062 shares of the Issuer, pursuant to which the reporting person now has direct beneficial ownership of her pro rata share of the securities formerly held by The Frost Group. The reporting person previously reported that the shares were owned directly by The Frost Group."}],"balance_after":27599870,"source":{"system":"sec-edgar","filing":"0001209191-21-050591","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919121050591/doc4.xml","form_type":"4"}},{"id":2646217,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option","published_at":"2021-07-02T19:06:37.000Z","date":"2021-06-30","kind":"grant","acquired":true,"shares":3748,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"security","element":"securityTitle","label":"F4","text":"Represents an equity award issued under the Registrant's Amended and Restated Incentive Compensation Plan in lieu of an annual cash retainer, paid quarterly in arrears for the quarter ended June 30, 2021."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The award is fully exercisable six months after the grant date, subject to earlier acceleration as approved by the Board of Directors."}],"balance_after":3748,"derivative":{"exercise_price":3.17,"exercise_date":"2021-12-31","expiration_date":"2028-06-30","underlying":"Common Stock","underlying_shares":3748},"source":{"system":"sec-edgar","filing":"0001209191-21-045178","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919121045178/doc4.xml","form_type":"4"}},{"id":2646216,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2021-07-02T19:06:37.000Z","date":"2021-07-01","kind":"grant","acquired":true,"shares":29231,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents restricted stock units (\"RSUs\"). Each RSU represents the right to receive one share of the Registrant's common stock."},{"field":"shares","element":"transactionShares","label":"F2","text":"Forfeiture restrictions will lapse on the RSUs on the first anniversary of the date of grant, provided that if the date of the 2022 annual meeting of stockholders is earlier, the restrictions will lapse on the date of the annual meeting."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Represents restricted stock units (\"RSUs\"). Each RSU represents the right to receive one share of the Registrant's common stock."}],"balance_after":336895,"source":{"system":"sec-edgar","filing":"0001209191-21-045178","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919121045178/doc4.xml","form_type":"4"}},{"id":2762654,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option","published_at":"2021-04-02T18:15:39.000Z","date":"2021-03-31","kind":"grant","acquired":true,"shares":3155,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"Represents an equity award issued under the Registrant's Amended and Restated Incentive Compensation Plan in lieu of an annual cash retainer, paid quarterly in arrears for the quarter ended March 31, 2021."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The award is fully exercisable six months after the grant date, subject to earlier acceleration as approved by the Board of Directors."}],"balance_after":3155,"derivative":{"exercise_price":3.25,"exercise_date":"2021-10-01","expiration_date":"2028-03-31","underlying":"Common Stock","underlying_shares":3155},"source":{"system":"sec-edgar","filing":"0001209191-21-024776","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919121024776/doc4.xml","form_type":"4"}},{"id":2844237,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Stock Option (Right to Buy)","published_at":"2021-02-22T21:08:58.000Z","date":"2021-02-19","kind":"grant","acquired":true,"shares":400000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option will vest in four equal annual installments beginning February 19, 2022."}],"balance_after":400000,"derivative":{"exercise_price":4.81,"expiration_date":"2031-02-18","underlying":"Common Stock","underlying_shares":400000},"source":{"system":"sec-edgar","filing":"0001209191-21-012667","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919121012667/doc4.xml","form_type":"4"}},{"id":2923361,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option","published_at":"2021-01-05T19:10:56.000Z","date":"2020-12-31","kind":"grant","acquired":true,"shares":12831,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"Represents an equity award issued under the Registrant's Amended and Restated Incentive Compensation Plan in lieu of an annual cash retainer, paid quarterly in arrears for the quarter ended December 31, 2020."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The award is fully exercisable six months after the grant date, subject to earlier acceleration as approved by the Board of Directors."}],"balance_after":12831,"derivative":{"exercise_price":0.63,"exercise_date":"2021-07-01","expiration_date":"2028-12-31","underlying":"Common Stock","underlying_shares":12831},"source":{"system":"sec-edgar","filing":"0001209191-21-001611","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919121001611/doc4.xml","form_type":"4"}},{"id":3017360,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option","published_at":"2020-10-02T17:36:44.000Z","date":"2020-09-30","kind":"grant","acquired":true,"shares":12915,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"Represents an equity award issued under the Registrant's Amended and Restated Incentive Compensation Plan in lieu of an annual cash retainer, paid quarterly in arrears for the quarter ended September 30, 2020."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The award is fully exercisable six months after the grant date, subject to earlier acceleration as approved by the Board of Directors."}],"balance_after":12915,"derivative":{"exercise_price":0.35,"exercise_date":"2021-03-30","expiration_date":"2027-09-30","underlying":"Common Stock","underlying_shares":12915},"source":{"system":"sec-edgar","filing":"0001209191-20-053286","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919120053286/doc4.xml","form_type":"4"}},{"id":3115403,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option","published_at":"2020-06-10T20:53:53.000Z","date":"2020-06-08","kind":"grant","acquired":true,"shares":31250,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"The stock options will vest 25% on each of September 8, 2020, December 8, 2020, March 8, 2021 and June 8, 2021, provided that if the date of the 2021 annual meeting of stockholders is earlier, the last vesting occurs on the date of the annual meeting. Subject to acceleration of vesting in full upon consummation of a change in control of the Registrant."}],"balance_after":31250,"derivative":{"exercise_price":0.82,"expiration_date":"2027-06-08","underlying":"Common Stock","underlying_shares":31250},"source":{"system":"sec-edgar","filing":"0001209191-20-035741","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919120035741/doc4.xml","form_type":"4"}},{"id":3115402,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2020-06-10T20:53:53.000Z","date":"2020-06-08","kind":"grant","acquired":true,"shares":22500,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents restricted stock units. Each restricted stock unit represents the right to receive one share of the Registrant's common stock."},{"field":"shares","element":"transactionShares","label":"F2","text":"The restricted stock units remain subject to forfeiture until the first anniversary of the date of grant or, if earlier, the date of the next annual meeting of stockholders, as long as the Reporting Person remains in continuous service during the vesting period."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Represents restricted stock units. Each restricted stock unit represents the right to receive one share of the Registrant's common stock."}],"balance_after":307664,"source":{"system":"sec-edgar","filing":"0001209191-20-035741","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919120035741/doc4.xml","form_type":"4"}},{"id":3115401,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2020-06-10T20:53:53.000Z","date":"2020-06-08","kind":"grant","acquired":true,"shares":7988,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents restricted stock units. Each restricted stock unit represents the right to receive one share of the Registrant's common stock."},{"field":"shares","element":"transactionShares","label":"F2","text":"The restricted stock units remain subject to forfeiture until the first anniversary of the date of grant or, if earlier, the date of the next annual meeting of stockholders, as long as the Reporting Person remains in continuous service during the vesting period."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Represents restricted stock units. Each restricted stock unit represents the right to receive one share of the Registrant's common stock."}],"balance_after":285164,"source":{"system":"sec-edgar","filing":"0001209191-20-035741","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919120035741/doc4.xml","form_type":"4"}},{"id":3119241,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Stock Option (Right to Buy)","published_at":"2020-06-08T20:15:37.000Z","date":"2020-06-04","kind":"grant","acquired":true,"shares":450000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option will vest in four equal annual installments beginning June 4, 2021."}],"balance_after":450000,"derivative":{"exercise_price":2.27,"expiration_date":"2030-06-03","underlying":"Common Stock","underlying_shares":450000},"source":{"system":"sec-edgar","filing":"0001209191-20-034965","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919120034965/doc4.xml","form_type":"4"}},{"id":3388040,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-10-25T18:10:25.000Z","date":"2019-10-25","kind":"purchase","acquired":true,"shares":400000,"price":1.5,"value":600000.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The securities are owned directly by Hsu Gamma Investment, L.P.  Dr. Hsiao is the general partner of Hsu Gamma Investment, L.P.  The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose."}],"balance_after":5127404,"source":{"system":"sec-edgar","filing":"0001209191-19-054066","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119054066/doc4.xml","form_type":"4"}},{"id":3469083,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Stock Option (Right to Buy)","published_at":"2019-07-03T17:05:49.000Z","date":"2019-07-01","kind":"grant","acquired":true,"shares":350000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option will vest in four equal annual installments beginning July 1, 2020."}],"balance_after":350000,"derivative":{"exercise_price":2.47,"expiration_date":"2029-06-30","underlying":"Common Stock","underlying_shares":350000},"source":{"system":"sec-edgar","filing":"0001209191-19-040731","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119040731/doc4.xml","form_type":"4"}},{"id":3532198,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-05-10T10:17:33.000Z","date":"2019-05-09","kind":"purchase","acquired":true,"shares":2783,"price":2.04,"value":5677.32,"ownership":{"direct":true},"balance_after":24475147,"source":{"system":"sec-edgar","filing":"0001209191-19-028670","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119028670/doc4.xml","form_type":"4"}},{"id":3532197,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-05-10T10:17:33.000Z","date":"2019-05-09","kind":"purchase","acquired":true,"shares":500,"price":2.035,"value":1017.5,"ownership":{"direct":true},"balance_after":24472364,"source":{"system":"sec-edgar","filing":"0001209191-19-028670","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119028670/doc4.xml","form_type":"4"}},{"id":3532196,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-05-10T10:17:33.000Z","date":"2019-05-09","kind":"purchase","acquired":true,"shares":6717,"price":2.025,"value":13601.925,"ownership":{"direct":true},"balance_after":24471864,"source":{"system":"sec-edgar","filing":"0001209191-19-028670","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119028670/doc4.xml","form_type":"4"}},{"id":3548078,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option Award","published_at":"2019-04-26T20:01:36.000Z","date":"2019-04-25","kind":"grant","acquired":true,"shares":29104,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"The vesting schedule is 25% of the stock option award on July 1, 2019, October 1, 2019, January 1, 2020 and April 1, 2020.  Subject to acceleration of vesting in full upon consummation of a change in control of the registrant."}],"balance_after":29104,"derivative":{"exercise_price":1.96,"expiration_date":"2029-04-25","underlying":"Common Stock","underlying_shares":29104},"source":{"system":"sec-edgar","filing":"0001209191-19-026316","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919119026316/doc4.xml","form_type":"4"}},{"id":3548077,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2019-04-26T20:01:36.000Z","date":"2019-04-25","kind":"grant","acquired":true,"shares":20380,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents restricted stock units. Each restricted stock unit represents the right to receive one share of the Registrant's common stock."},{"field":"shares","element":"transactionShares","label":"F2","text":"The restricted stock units remain subject to forfeiture until the first anniversary of the date of grant or, if earlier, the date of the next annual meeting of stockholders, as long as the reporting person remains in continuous service during the vesting period."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Represents restricted stock units. Each restricted stock unit represents the right to receive one share of the Registrant's common stock."}],"balance_after":3603278,"source":{"system":"sec-edgar","filing":"0001209191-19-026316","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919119026316/doc4.xml","form_type":"4"}},{"id":3675467,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:31:07.000Z","date":"2018-12-13","kind":"gift","acquired":false,"shares":1000000,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The securities are held by The Chin Hsiao Family Trust B, of which Jane H. Hsiao, Ph.D. is the trustee."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001209191-19-007347","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007347/doc4.xml","form_type":"4"}},{"id":3675466,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:31:07.000Z","date":"2018-12-13","kind":"gift","acquired":false,"shares":1000000,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are held by The Chin Hsiao Family Trust A, of which Jane H. Hsiao, Ph.D. is the trustee."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001209191-19-007347","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007347/doc4.xml","form_type":"4"}},{"id":3675465,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:31:07.000Z","date":"2012-07-30","kind":"purchase","acquired":true,"shares":30000,"price":4.35,"value":130500.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The securities are owned directly by Hsu Gamma Investment, L.P.  Dr. Hsiao is the general partner of Hsu Gamma Investment, L.P.  The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose."}],"balance_after":4727404,"source":{"system":"sec-edgar","filing":"0001209191-19-007347","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007347/doc4.xml","form_type":"4"}},{"id":3675464,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:31:07.000Z","date":"2012-07-27","kind":"purchase","acquired":true,"shares":20000,"price":4.3,"value":86000.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The securities are owned directly by Hsu Gamma Investment, L.P.  Dr. Hsiao is the general partner of Hsu Gamma Investment, L.P.  The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose."}],"balance_after":4697404,"source":{"system":"sec-edgar","filing":"0001209191-19-007347","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007347/doc4.xml","form_type":"4"}},{"id":3675463,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:31:07.000Z","date":"2014-01-31","kind":"purchase","acquired":true,"shares":10000,"price":7.96,"value":79600.0,"ownership":{"direct":true},"balance_after":24465147,"source":{"system":"sec-edgar","filing":"0001209191-19-007347","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007347/doc4.xml","form_type":"4"}},{"id":3675462,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:31:07.000Z","date":"2011-12-21","kind":"gift","acquired":false,"shares":831052,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":24455147,"source":{"system":"sec-edgar","filing":"0001209191-19-007347","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007347/doc4.xml","form_type":"4"}},{"id":3675461,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:30:19.000Z","date":"2017-05-11","kind":"purchase","acquired":true,"shares":10000,"price":6.93,"value":69300.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"date","element":"transactionDate","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 12, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"kind","element":"transactionCoding","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 12, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are owned directly by Hsu Gamma Investment, L.P.  Dr. Hsiao is the general partner of Hsu Gamma Investment, L.P.  The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose."}],"balance_after":4677404,"source":{"system":"sec-edgar","filing":"0001209191-19-007346","document":"doc4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007346/doc4a.xml","form_type":"4/A","original_submission_date":"2017-05-12"}},{"id":3675460,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:30:19.000Z","date":"2017-05-11","kind":"purchase","acquired":true,"shares":10000,"price":6.92,"value":69200.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"date","element":"transactionDate","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 12, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"kind","element":"transactionCoding","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 12, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are owned directly by Hsu Gamma Investment, L.P.  Dr. Hsiao is the general partner of Hsu Gamma Investment, L.P.  The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose."}],"balance_after":4667404,"source":{"system":"sec-edgar","filing":"0001209191-19-007346","document":"doc4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007346/doc4a.xml","form_type":"4/A","original_submission_date":"2017-05-12"}},{"id":3675458,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:26:52.000Z","date":"2017-05-10","kind":"purchase","acquired":true,"shares":10000,"price":6.99,"value":69900.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"date","element":"transactionDate","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 11, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"kind","element":"transactionCoding","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 11, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are owned directly by Hsu Gamma Investment, L.P.  Dr. Hsiao is the general partner of Hsu Gamma Investment, L.P.  The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose."}],"balance_after":4657404,"source":{"system":"sec-edgar","filing":"0001209191-19-007339","document":"doc4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007339/doc4a.xml","form_type":"4/A","original_submission_date":"2017-05-11"}},{"id":3675457,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:26:52.000Z","date":"2017-05-10","kind":"purchase","acquired":true,"shares":5665,"price":6.98,"value":39541.7,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"date","element":"transactionDate","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 11, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"kind","element":"transactionCoding","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 11, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are owned directly by Hsu Gamma Investment, L.P.  Dr. Hsiao is the general partner of Hsu Gamma Investment, L.P.  The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose."}],"balance_after":4647404,"source":{"system":"sec-edgar","filing":"0001209191-19-007339","document":"doc4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007339/doc4a.xml","form_type":"4/A","original_submission_date":"2017-05-11"}},{"id":3675456,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:26:52.000Z","date":"2017-05-10","kind":"purchase","acquired":true,"shares":11735,"price":6.97,"value":81792.95,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"date","element":"transactionDate","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 11, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"kind","element":"transactionCoding","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 11, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are owned directly by Hsu Gamma Investment, L.P.  Dr. Hsiao is the general partner of Hsu Gamma Investment, L.P.  The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose."}],"balance_after":4641739,"source":{"system":"sec-edgar","filing":"0001209191-19-007339","document":"doc4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007339/doc4a.xml","form_type":"4/A","original_submission_date":"2017-05-11"}},{"id":3675455,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:26:52.000Z","date":"2017-05-10","kind":"purchase","acquired":true,"shares":2600,"price":6.95,"value":18070.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"date","element":"transactionDate","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 11, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"kind","element":"transactionCoding","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 11, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are owned directly by Hsu Gamma Investment, L.P.  Dr. Hsiao is the general partner of Hsu Gamma Investment, L.P.  The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose."}],"balance_after":4630004,"source":{"system":"sec-edgar","filing":"0001209191-19-007339","document":"doc4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007339/doc4a.xml","form_type":"4/A","original_submission_date":"2017-05-11"}},{"id":3675454,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2019-02-05T21:26:52.000Z","date":"2017-05-10","kind":"purchase","acquired":true,"shares":10000,"price":6.94,"value":69400.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"date","element":"transactionDate","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 11, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"kind","element":"transactionCoding","label":"F1","text":"The securities were erroneously reported as being purchased by the reporting person and owned directly on a Form 4 filed on May 11, 2017.  The securities were purchased by Hsu Gamma Investment, L.P. and are owned indirectly by the reporting person.  This Form 4 corrects the name and ownership of the securities.  No other information has changed."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are owned directly by Hsu Gamma Investment, L.P.  Dr. Hsiao is the general partner of Hsu Gamma Investment, L.P.  The reporting person disclaims beneficial ownership of these securities, except to the extent of any pecuniary interest therein and this report shall not be deemed an admission that the reporting person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose."}],"balance_after":4627404,"source":{"system":"sec-edgar","filing":"0001209191-19-007339","document":"doc4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919119007339/doc4a.xml","form_type":"4/A","original_submission_date":"2017-05-11"}},{"id":3718725,"issuer":{"id":7976,"kind":"organization","name":"NON INVASIVE MONITORING SYSTEMS INC /FL/"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":true,"other":false,"officer_title":"Interim CEO"}}],"security":"Common Stock, $0.01 par value per share","published_at":"2018-12-28T00:36:06.000Z","date":"2018-12-21","kind":"purchase","acquired":true,"shares":20883660,"price":0.07,"value":1461856.2,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Shares acquired in exchange for indebtedness owed by Non-Invasive Monitoring Systems, Inc. to the reporting person or affiliates thereof."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Shares acquired in exchange for indebtedness owed by Non-Invasive Monitoring Systems, Inc. to the reporting person or affiliates thereof."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Held by Hsu Gamma Investments LP, of which the reporting person is the general partner. The reporting person disclaims beneficial ownership of all shares held by Hsu Gamma Investments, LP except to the extent of her pecuniary interest therein, and the inclusion of these shares in this report shall not be deemed an admission of beneficial ownership of all of the reported shares for purposes of Section 16 or for any other purpose."}],"balance_after":20883660,"source":{"system":"sec-edgar","filing":"0001493152-18-018021","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/720762/000149315218018021/ownership.xml","form_type":"4"}},{"id":3718724,"issuer":{"id":7976,"kind":"organization","name":"NON INVASIVE MONITORING SYSTEMS INC /FL/"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":true,"other":false,"officer_title":"Interim CEO"}}],"security":"Common Stock, $0.01 par value per share","published_at":"2018-12-28T00:36:06.000Z","date":"2018-12-21","kind":"purchase","acquired":true,"shares":4923503,"price":0.07,"value":344645.21,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Shares acquired in exchange for indebtedness owed by Non-Invasive Monitoring Systems, Inc. to the reporting person or affiliates thereof."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Shares acquired in exchange for indebtedness owed by Non-Invasive Monitoring Systems, Inc. to the reporting person or affiliates thereof."}],"balance_after":16752074,"source":{"system":"sec-edgar","filing":"0001493152-18-018021","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/720762/000149315218018021/ownership.xml","form_type":"4"}},{"id":3718723,"issuer":{"id":7976,"kind":"organization","name":"NON INVASIVE MONITORING SYSTEMS INC /FL/"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":true,"other":false,"officer_title":"Interim CEO"}}],"security":"Common Stock, $0.01 par value per share","published_at":"2018-12-28T00:36:06.000Z","date":"2018-12-21","kind":"purchase","acquired":true,"shares":1428571,"price":0.07,"value":99999.97,"ownership":{"direct":true},"balance_after":11828571,"source":{"system":"sec-edgar","filing":"0001493152-18-018021","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/720762/000149315218018021/ownership.xml","form_type":"4"}},{"id":3768426,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2018-11-13T12:42:54.000Z","date":"2018-11-08","kind":"grant","acquired":true,"shares":573066,"price":3.49,"value":2000000.34,"ownership":{"direct":true},"balance_after":25346199,"source":{"system":"sec-edgar","filing":"0001209191-18-058057","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919118058057/doc4.xml","form_type":"4"}},{"id":3809005,"issuer":{"id":7621,"kind":"organization","name":"Cocrystal Pharma, Inc."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Options (Right to Buy)","published_at":"2018-09-24T20:56:30.000Z","date":"2018-09-21","kind":"grant","acquired":true,"shares":50000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The stock options vest as follows: 1/4 will vest on the one year anniversary of the grant date and the remaining 3/4 will vest in 12 equal quarterly increments."}],"balance_after":50000,"derivative":{"exercise_price":2.78,"expiration_date":"2028-09-20","underlying":"Common Stock","underlying_shares":50000},"source":{"system":"sec-edgar","filing":"0001493152-18-013674","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1412486/000149315218013674/ownership.xml","form_type":"4"}},{"id":3885434,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Stock Option (Right to Buy)","published_at":"2018-06-22T20:12:30.000Z","date":"2018-06-21","kind":"grant","acquired":true,"shares":500000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The options were granted on June 21, 2018 and vest annually in four equal installments beginning on June 21, 2019."}],"balance_after":500000,"derivative":{"exercise_price":4.46,"expiration_date":"2028-06-20","underlying":"Common Stock","underlying_shares":500000},"source":{"system":"sec-edgar","filing":"0001209191-18-039168","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919118039168/doc4.xml","form_type":"4"}},{"id":3916211,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option Award","published_at":"2018-05-29T06:59:57.000Z","date":"2018-05-24","kind":"grant","acquired":true,"shares":35592,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"The vesting schedule is 25% of the stock option award on each of July 1, 2018, October 1, 2018, January 1, 2019 and April 1, 2019."}],"balance_after":35592,"derivative":{"exercise_price":3.17,"expiration_date":"2028-05-24","underlying":"Common Stock","underlying_shares":35592},"source":{"system":"sec-edgar","filing":"0001209191-18-033656","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919118033656/doc4.xml","form_type":"4"}},{"id":3916210,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2018-05-29T06:59:57.000Z","date":"2018-05-24","kind":"grant","acquired":true,"shares":20362,"ownership":{"direct":true},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"Represents restricted stock units.  Each restricted stock unit represents the right to receive one share of the Registrant's common stock."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Represents restricted stock units.  Each restricted stock unit represents the right to receive one share of the Registrant's common stock."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The restricted stock units remain subject to forfeiture until the first anniversary of the date of grant or, if earlier, the date of the next annual meeting of stockholders, as long as the reporting person remains in continuous service during the vesting period."}],"balance_after":3582898,"source":{"system":"sec-edgar","filing":"0001209191-18-033656","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919118033656/doc4.xml","form_type":"4"}},{"id":3983465,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Warrants","published_at":"2018-03-26T08:30:21.000Z","date":"2018-03-22","kind":"other","acquired":false,"shares":400000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"On March 22, 2018, the reporting person exercised warrants to purchase 400,000 shares of common stock of TransEnterix, Inc., par value $0.001 per share, for a purchase price of $1.65 per share."}],"balance_after":0,"derivative":{"exercise_price":1.65,"exercise_date":"2013-03-22","expiration_date":"2018-03-22","underlying":"Common Stock","underlying_shares":400000},"source":{"system":"sec-edgar","filing":"0001209191-18-021583","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919118021583/doc4.xml","form_type":"4"}},{"id":3983464,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2018-03-26T08:30:21.000Z","date":"2018-03-22","kind":"other","acquired":true,"shares":400000,"price":1.65,"value":660000.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"On March 22, 2018, the reporting person exercised warrants to purchase 400,000 shares of common stock of TransEnterix, Inc., par value $0.001 per share, for a purchase price of $1.65 per share."}],"balance_after":3562536,"source":{"system":"sec-edgar","filing":"0001209191-18-021583","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919118021583/doc4.xml","form_type":"4"}},{"id":4025048,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"5% Convertible Promissory Note","published_at":"2018-03-01T21:10:29.000Z","date":"2018-02-27","kind":"grant","acquired":true,"price":5000000,"reported_value":5000000,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"The Reporting Person has the option, from time to time, to convert all or any portion of the outstanding principal balance of the 5% Convertible Promissory Note (the \"Note\"), together with accrued and unpaid interest thereon, into shares of the Issuer's common stock, par value $0.01 per share (\"Common Stock\"), at a conversion price of $5.00 per share of Common Stock."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The Note may be converted at any time prior to the Maturity Date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"The Notes will mature on February 27, 2023, unless repurchased, redeemed or converted prior to such date."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F4","text":"Based on the principal amount of the Note, excluding shares issuable upon conversion of accrued and unpaid interest as of the date of conversion."},{"field":"valueOwnedAfter","element":"valueOwnedFollowingTransaction","label":"F4","text":"Based on the principal amount of the Note, excluding shares issuable upon conversion of accrued and unpaid interest as of the date of conversion."}],"derivative":{"exercise_price":5,"expiration_date":"2023-02-27","underlying":"Common Stock","underlying_shares":1000000},"source":{"system":"sec-edgar","filing":"0001209191-18-014956","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919118014956/doc4.xml","form_type":"4"}},{"id":4303795,"issuer":{"id":88098,"kind":"organization","name":"ASENSUS SURGICAL, INC.","symbol":"ASXC"},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option Award","published_at":"2017-05-26T16:17:34.000Z","date":"2017-05-25","kind":"grant","acquired":true,"shares":20000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Vests 25% per quarter on each quarterly anniversary of the date of grant with the final vesting on the first anniversary of the date of grant."}],"balance_after":20000,"derivative":{"exercise_price":0.48,"expiration_date":"2027-05-25","underlying":"Common Stock","underlying_shares":20000},"source":{"system":"sec-edgar","filing":"0001209191-17-035807","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/876378/000120919117035807/doc4.xml","form_type":"4"}},{"id":4323442,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2017-05-12T14:53:56.000Z","date":"2017-05-11","kind":"purchase","acquired":true,"shares":10000,"price":6.93,"value":69300.0,"ownership":{"direct":true},"balance_after":24773133,"source":{"system":"sec-edgar","filing":"0001209191-17-031741","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919117031741/doc4.xml","form_type":"4"}},{"id":4323441,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2017-05-12T14:53:56.000Z","date":"2017-05-11","kind":"purchase","acquired":true,"shares":10000,"price":6.92,"value":69200.0,"ownership":{"direct":true},"balance_after":24763133,"source":{"system":"sec-edgar","filing":"0001209191-17-031741","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919117031741/doc4.xml","form_type":"4"}},{"id":4325514,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2017-05-11T10:50:53.000Z","date":"2017-05-10","kind":"purchase","acquired":true,"shares":10000,"price":6.99,"value":69900.0,"ownership":{"direct":true},"balance_after":24753133,"source":{"system":"sec-edgar","filing":"0001209191-17-031425","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919117031425/doc4.xml","form_type":"4"}},{"id":4325513,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2017-05-11T10:50:53.000Z","date":"2017-05-10","kind":"purchase","acquired":true,"shares":5665,"price":6.98,"value":39541.7,"ownership":{"direct":true},"balance_after":24743133,"source":{"system":"sec-edgar","filing":"0001209191-17-031425","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919117031425/doc4.xml","form_type":"4"}},{"id":4325512,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2017-05-11T10:50:53.000Z","date":"2017-05-10","kind":"purchase","acquired":true,"shares":11735,"price":6.97,"value":81792.95,"ownership":{"direct":true},"balance_after":24737468,"source":{"system":"sec-edgar","filing":"0001209191-17-031425","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919117031425/doc4.xml","form_type":"4"}},{"id":4325511,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2017-05-11T10:50:53.000Z","date":"2017-05-10","kind":"purchase","acquired":true,"shares":2600,"price":6.95,"value":18070.0,"ownership":{"direct":true},"balance_after":24725733,"source":{"system":"sec-edgar","filing":"0001209191-17-031425","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919117031425/doc4.xml","form_type":"4"}},{"id":4325510,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2017-05-11T10:50:53.000Z","date":"2017-05-10","kind":"purchase","acquired":true,"shares":10000,"price":6.94,"value":69400.0,"ownership":{"direct":true},"balance_after":24723133,"source":{"system":"sec-edgar","filing":"0001209191-17-031425","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919117031425/doc4.xml","form_type":"4"}},{"id":4499748,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Stock Option (Right to Buy)","published_at":"2017-01-05T16:11:26.000Z","date":"2017-01-04","kind":"exercise","acquired":false,"shares":112500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The options were granted on March 18, 2013 and vest in four equal installments beginning on March 18, 2014."}],"balance_after":112500,"derivative":{"exercise_price":7.61,"expiration_date":"2020-03-17","underlying":"Common Stock","underlying_shares":112500},"source":{"system":"sec-edgar","filing":"0001209191-17-001677","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919117001677/doc4.xml","form_type":"4"}},{"id":4499747,"issuer":{"id":4891,"kind":"organization","name":"OPKO HEALTH, INC."},"owners":[{"id":79126,"kind":"person","name":"HSIAO JANE PH D","position":1,"cik":"0001188834","reported_name":"HSIAO JANE PH D","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Vice Chairman & CTO"}}],"security":"Common Stock","published_at":"2017-01-05T16:11:26.000Z","date":"2017-01-04","kind":"exercise","acquired":true,"shares":112500,"price":7.61,"value":856125.0,"ownership":{"direct":true},"balance_after":24713133,"source":{"system":"sec-edgar","filing":"0001209191-17-001677","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/944809/000120919117001677/doc4.xml","form_type":"4"}}]}