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The RSUs have no expiration date."},{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F4","text":"Pursuant to the terms of the Transaction Agreement, immediately prior to the Effective Time, each outstanding time-based restricted share unit award (\"RSU Award\"), unless agreed otherwise, became fully vested, and at the Effective Time, was automatically converted into the right to receive an amount in cash (without interest and subject to all required withholding taxes) equal to the product of (i) the aggregate number of ADSs underlying such RSU Award and (ii) the ADS Consideration."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"Pursuant to the terms of the Transaction Agreement, immediately prior to the Effective Time, each outstanding time-based restricted share unit award (\"RSU Award\"), unless agreed otherwise, became fully vested, and at the Effective Time, was automatically converted into the right to receive an 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The RSUs have no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The RSUs vest as to 25% of the total shares on each of August 1, 2025, November 1, 2025, February 1, 2026 and May 1, 2026 subject to the Reporting Person's continued service to the Issuer on each vesting date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F5","text":"Represents an award of RSUs covering ADSs, which is presented in terms of the equivalent number of Ordinary Shares underlying the ADSs. Each RSU represents a contingent right to receive one (1) ADS of the Issuer. Each ADS represents eight (8) Ordinary Shares of the Issuer. 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The RSUs have no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The RSUs vest as to 25% of the total shares on each of August 1, 2025, November 1, 2025, February 1, 2026 and May 1, 2026 subject to the Reporting Person's continued service to the Issuer on each vesting date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Represents an award of Restricted Share Units (\"RSUs\") covering American Depositary Shares (\"ADSs\").  Each RSU represents a contingent right to receive one (1) ADS of the Issuer.  Each ADS represents eight (8) Ordinary Shares of the Issuer.  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option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares, each of which represents eight (8) Ordinary Shares of the Issuer."},{"field":"shares","element":"transactionShares","label":"F1","text":"The number of securities underlying the option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares, each of which represents eight (8) Ordinary Shares of the Issuer."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option vests and becomes exercisable as to 25% on each of July 29, 2024, October 29, 2024, January 29, 2025 and April 29, 2025."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F1","text":"The number of securities underlying the option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares, each of which represents eight (8) Ordinary Shares of the Issuer."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"The number of securities underlying the option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares, each of which represents eight (8) Ordinary Shares of the Issuer."}],"balance_after":240000,"derivative":{"exercise_price":1.9338,"expiration_date":"2034-04-28","underlying":"Ordinary Shares","underlying_shares":240000},"source":{"system":"sec-edgar","filing":"0001104659-24-054950","document":"tm2412993-7_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1255449/000110465924054950/tm2412993-7_4seq1.xml","form_type":"4"}},{"id":1849409,"issuer":{"id":15659,"kind":"organization","name":"IPI Legacy Liquidation 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June 12, 2024 or the day immediately prior to the next annual meeting of stockholders, subject to the Reporting Person's continuous service through such date; provided, however that the option will vest in full upon a change in control of the Issuer."}],"balance_after":25000,"derivative":{"exercise_price":1.63,"expiration_date":"2033-06-11","underlying":"Common Stock","underlying_shares":25000},"source":{"system":"sec-edgar","filing":"0001209191-23-037117","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1641281/000120919123037117/doc4.xml","form_type":"4"}},{"id":1911207,"issuer":{"id":74409,"kind":"organization","name":"Verona Pharma plc","symbol":"VRNA"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Share 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option vests and becomes exercisable as to 25% on each of July 28, 2023, October 28, 2023, January 28, 2024 and April 28, 2024."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F1","text":"The number of securities underlying the option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares (\"ADSs\"), each of which represents eight (8) Ordinary Shares of the Issuer."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"The number of securities underlying the option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares (\"ADSs\"), each of which represents eight (8) Ordinary Shares of the Issuer."}],"balance_after":96000,"derivative":{"exercise_price":2.67,"expiration_date":"2033-04-27","underlying":"Ordinary 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2023."}],"balance_after":12789,"derivative":{"exercise_price":8.65,"expiration_date":"2032-06-15","underlying":"Common Stock","underlying_shares":12789},"source":{"system":"sec-edgar","filing":"0001209191-22-037957","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1445499/000120919122037957/doc4.xml","form_type":"4"}},{"id":2235886,"issuer":{"id":8082,"kind":"organization","name":"Bolt Biotherapeutics, Inc.","symbol":"BOLT"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to 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therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares (\"ADSs\"), each of which represents eight (8) Ordinary Shares of the Issuer."},{"field":"shares","element":"transactionShares","label":"F1","text":"The number of securities underlying the option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares (\"ADSs\"), each of which represents eight (8) Ordinary Shares of the Issuer."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option vests and becomes exercisable as to 25% on each of July 28, 2022, October 28, 2022, January 28, 2023 and April 28, 2023."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F1","text":"The number of securities underlying the option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares (\"ADSs\"), each of which represents eight (8) Ordinary Shares of the Issuer."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"The number of securities underlying the option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares (\"ADSs\"), each of which represents eight (8) Ordinary Shares of the Issuer."}],"balance_after":200000,"derivative":{"exercise_price":0.5038,"expiration_date":"2032-04-27","underlying":"Ordinary Shares","underlying_shares":200000},"source":{"system":"sec-edgar","filing":"0001104659-22-053678","document":"tm2214046-1_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1255449/000110465922053678/tm2214046-1_4seq1.xml","form_type":"4"}},{"id":2316620,"issuer":{"id":8082,"kind":"organization","name":"Bolt Biotherapeutics, Inc.","symbol":"BOLT"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2022-03-28T19:18:18.000Z","date":"2022-03-24","kind":"grant","acquired":true,"shares":25000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to this option shall vest on the one-year anniversary of June 10, 2021 (the \"Vesting Commencement Date\") for so long as the Reporting Person provides continuous service to the Issuer, such that the total number of shares shall be fully vested on the one-year anniversary of the Vesting Commencement Date; provided, however that the option will vest in full upon a change in control of the Issuer."}],"balance_after":25000,"derivative":{"exercise_price":3.03,"expiration_date":"2032-03-23","underlying":"Common Stock","underlying_shares":25000},"source":{"system":"sec-edgar","filing":"0000899243-22-012456","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1641281/000089924322012456/doc4.xml","form_type":"4"}},{"id":2608269,"issuer":{"id":74409,"kind":"organization","name":"Verona Pharma plc","symbol":"VRNA"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Share Options (Right to Buy)","published_at":"2021-08-10T16:45:28.000Z","date":"2021-08-09","kind":"grant","acquired":true,"shares":64000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"The number of securities underlying the option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares (\"ADSs\"), each of which represents eight (8) Ordinary Shares of the Issuer."},{"field":"shares","element":"transactionShares","label":"F1","text":"The number of securities underlying the option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares (\"ADSs\"), each of which represents eight (8) Ordinary Shares of the Issuer."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option vests and becomes exercisable as to 25% on August 9, 2021, 25% on November 1, 2021, 25% on February 1, 2022 and 25% on May 1, 2022."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F1","text":"The number of securities underlying the option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares (\"ADSs\"), each of which represents eight (8) Ordinary Shares of the Issuer."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"The number of securities underlying the option and the exercise price therefor are listed in terms of Ordinary Shares, however, each security is represented by American Depositary Shares (\"ADSs\"), each of which represents eight (8) Ordinary Shares of the Issuer."}],"balance_after":64000,"derivative":{"exercise_price":0.775,"expiration_date":"2031-08-08","underlying":"Ordinary 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Shares","published_at":"2021-05-05T17:03:35.000Z","date":"2021-05-04","kind":"sale","acquired":false,"shares":10680,"price":0.8397,"value":8967.996,"ownership":{"direct":true},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"Reported securities are represented by American Depositary Shares (\"ADSs\"), each of which represents eight (8) Ordinary Shares of the Issuer."},{"field":"kind","element":"transactionCoding","label":"F2","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction solely with the intent to cover withholding taxes in connection with the settlement of Restricted Stock Units."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported is a weighted average price, and is based on the sale price of the ADSs divided by eight (8). The securities were sold in multiple transactions at per share prices ranging from $0.8063 to $0.8525. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote 3."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"Consists of 73,080 Ordinary Shares represented by 9,135 ADSs."}],"balance_after":73080,"source":{"system":"sec-edgar","filing":"0001104659-21-061801","document":"tm2115267-3_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1255449/000110465921061801/tm2115267-3_4seq1.xml","form_type":"4"}},{"id":2871900,"issuer":{"id":8082,"kind":"organization","name":"Bolt Biotherapeutics, Inc.","symbol":"BOLT"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Warrant (Right to Buy)","published_at":"2021-02-09T20:33:35.000Z","date":"2021-02-09","kind":"other","acquired":false,"shares":17711,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"By Vivo PANDA Fund, L.P."},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The shares subject to this warrant were fully vested prior to exercise."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities reported herein are held of record by Vivo PANDA Fund, L.P. (\"Vivo LP\"). Vivo Panda, LLC (\"Vivo LLC\") is the sole general partner of Vivo LP. The Reporting Person is a managing member of Vivo LLC and has shared voting and investment power over the securities beneficially owned by Vivo LP and may therefore be deemed to have or share beneficial ownership of the securities held directly by Vivo LP. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein."}],"balance_after":0,"derivative":{"exercise_price":0.07,"expiration_date":"2028-07-26","underlying":"Common Stock","underlying_shares":17711},"source":{"system":"sec-edgar","filing":"0001209191-21-008753","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1641281/000120919121008753/doc4.xml","form_type":"4"}},{"id":2871899,"issuer":{"id":8082,"kind":"organization","name":"Bolt Biotherapeutics, Inc.","symbol":"BOLT"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Series B Preferred Stock","published_at":"2021-02-09T20:33:35.000Z","date":"2021-02-09","kind":"exercise","acquired":false,"shares":472296,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"By Vivo PANDA Fund, L.P."},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F3","text":"The Series B Preferred Stock automatically converted into shares of Common Stock of the Issuer on a 1:1 basis immediately upon closing of the Issuer's IPO and had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The Series B Preferred Stock automatically converted into shares of Common Stock of the Issuer on a 1:1 basis immediately upon closing of the Issuer's IPO and had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"The Series B Preferred Stock automatically converted into shares of Common Stock of the Issuer on a 1:1 basis immediately upon closing of the Issuer's IPO and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities reported herein are held of record by Vivo PANDA Fund, L.P. (\"Vivo LP\"). Vivo Panda, LLC (\"Vivo LLC\") is the sole general partner of Vivo LP. The Reporting Person is a managing member of Vivo LLC and has shared voting and investment power over the securities beneficially owned by Vivo LP and may therefore be deemed to have or share beneficial ownership of the securities held directly by Vivo LP. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":472296},"source":{"system":"sec-edgar","filing":"0001209191-21-008753","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1641281/000120919121008753/doc4.xml","form_type":"4"}},{"id":2871898,"issuer":{"id":8082,"kind":"organization","name":"Bolt Biotherapeutics, Inc.","symbol":"BOLT"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Series A- 1 Preferred Stock","published_at":"2021-02-09T20:33:35.000Z","date":"2021-02-09","kind":"exercise","acquired":false,"shares":944056,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"By Vivo PANDA Fund, L.P."},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"The Series A-1 Preferred Stock automatically converted into shares of Common Stock of the Issuer on a 1:1 basis immediately upon closing of the Issuer's initial public offering (the \"IPO\") and had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The Series A-1 Preferred Stock automatically converted into shares of Common Stock of the Issuer on a 1:1 basis immediately upon closing of the Issuer's initial public offering (the \"IPO\") and had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"The Series A-1 Preferred Stock automatically converted into shares of Common Stock of the Issuer on a 1:1 basis immediately upon closing of the Issuer's initial public offering (the \"IPO\") and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities reported herein are held of record by Vivo PANDA Fund, L.P. (\"Vivo LP\"). Vivo Panda, LLC (\"Vivo LLC\") is the sole general partner of Vivo LP. The Reporting Person is a managing member of Vivo LLC and has shared voting and investment power over the securities beneficially owned by Vivo LP and may therefore be deemed to have or share beneficial ownership of the securities held directly by Vivo LP. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":944056},"source":{"system":"sec-edgar","filing":"0001209191-21-008753","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1641281/000120919121008753/doc4.xml","form_type":"4"}},{"id":2871897,"issuer":{"id":8082,"kind":"organization","name":"Bolt Biotherapeutics, Inc.","symbol":"BOLT"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2021-02-09T20:33:35.000Z","date":"2021-02-09","kind":"sale","acquired":false,"shares":62,"price":20,"value":1240.0,"ownership":{"direct":false,"nature":"By Vivo PANDA Fund, L.P."},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F4","text":"Upon closing of the Issuer's IPO, Vivo LP exercised a warrant to purchase 17,711 shares of the Issuer's Common Stock at an exercise price per share of $0.07. Vivo LP paid the exercise price on a cashless basis, resulting in the Issuer withholding 62 share subject to the warrant in order to pay the exercise price and issuing to Vivo LP the remaining 17,649 shares of Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities reported herein are held of record by Vivo PANDA Fund, L.P. (\"Vivo LP\"). Vivo Panda, LLC (\"Vivo LLC\") is the sole general partner of Vivo LP. The Reporting Person is a managing member of Vivo LLC and has shared voting and investment power over the securities beneficially owned by Vivo LP and may therefore be deemed to have or share beneficial ownership of the securities held directly by Vivo LP. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein."}],"balance_after":1448286,"source":{"system":"sec-edgar","filing":"0001209191-21-008753","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1641281/000120919121008753/doc4.xml","form_type":"4"}},{"id":2871896,"issuer":{"id":8082,"kind":"organization","name":"Bolt Biotherapeutics, Inc.","symbol":"BOLT"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2021-02-09T20:33:35.000Z","date":"2021-02-09","kind":"other","acquired":true,"shares":17711,"price":0.07,"value":1239.77,"ownership":{"direct":false,"nature":"By Vivo PANDA Fund, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities reported herein are held of record by Vivo PANDA Fund, L.P. (\"Vivo LP\"). Vivo Panda, LLC (\"Vivo LLC\") is the sole general partner of Vivo LP. The Reporting Person is a managing member of Vivo LLC and has shared voting and investment power over the securities beneficially owned by Vivo LP and may therefore be deemed to have or share beneficial ownership of the securities held directly by Vivo LP. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein."}],"balance_after":1448348,"source":{"system":"sec-edgar","filing":"0001209191-21-008753","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1641281/000120919121008753/doc4.xml","form_type":"4"}},{"id":2871895,"issuer":{"id":8082,"kind":"organization","name":"Bolt Biotherapeutics, Inc.","symbol":"BOLT"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2021-02-09T20:33:35.000Z","date":"2021-02-09","kind":"exercise","acquired":true,"shares":472296,"ownership":{"direct":false,"nature":"By Vivo PANDA Fund, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The Series B Preferred Stock automatically converted into shares of Common Stock of the Issuer on a 1:1 basis immediately upon closing of the Issuer's IPO and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities reported herein are held of record by Vivo PANDA Fund, L.P. (\"Vivo LP\"). Vivo Panda, LLC (\"Vivo LLC\") is the sole general partner of Vivo LP. The Reporting Person is a managing member of Vivo LLC and has shared voting and investment power over the securities beneficially owned by Vivo LP and may therefore be deemed to have or share beneficial ownership of the securities held directly by Vivo LP. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein."}],"balance_after":1430637,"source":{"system":"sec-edgar","filing":"0001209191-21-008753","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1641281/000120919121008753/doc4.xml","form_type":"4"}},{"id":2871894,"issuer":{"id":8082,"kind":"organization","name":"Bolt Biotherapeutics, Inc.","symbol":"BOLT"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2021-02-09T20:33:35.000Z","date":"2021-02-09","kind":"exercise","acquired":true,"shares":944056,"ownership":{"direct":false,"nature":"By Vivo PANDA Fund, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The Series A-1 Preferred Stock automatically converted into shares of Common Stock of the Issuer on a 1:1 basis immediately upon closing of the Issuer's initial public offering (the \"IPO\") and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities reported herein are held of record by Vivo PANDA Fund, L.P. (\"Vivo LP\"). Vivo Panda, LLC (\"Vivo LLC\") is the sole general partner of Vivo LP. The Reporting Person is a managing member of Vivo LLC and has shared voting and investment power over the securities beneficially owned by Vivo LP and may therefore be deemed to have or share beneficial ownership of the securities held directly by Vivo LP. The Reporting Person disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein."}],"balance_after":958341,"source":{"system":"sec-edgar","filing":"0001209191-21-008753","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1641281/000120919121008753/doc4.xml","form_type":"4"}},{"id":2881101,"issuer":{"id":74409,"kind":"organization","name":"Verona Pharma plc","symbol":"VRNA"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2021-02-03T19:10:14.000Z","date":"2021-02-01","kind":"sale","acquired":false,"shares":10800,"price":0.9938,"value":10733.04,"ownership":{"direct":true},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"Reported securities are represented by American Depositary Shares (\"ADSs\"), each of which represents eight (8) Ordinary Shares of the Issuer."},{"field":"kind","element":"transactionCoding","label":"F2","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction solely with the intent to cover withholding taxes in connection with the settlement of Restricted Stock Units."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported is a weighted average price, and is based on the sale price of the ADSs divided by eight (8). The securities were sold in multiple transactions at per share prices ranging from $0.99375 to $0.99625. The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote 3."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"Consists of (i) 29,000 Ordinary Shares underlying Restricted Share Units, each of which represents a contingent right to receive one (1) Ordinary Share of the Issuer (which are represented by 3,625 ADSs); and (ii) 54,760 Ordinary Shares represented by 6,845 ADSs."}],"balance_after":83760,"source":{"system":"sec-edgar","filing":"0001104659-21-011747","document":"tm215272-4_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1255449/000110465921011747/tm215272-4_4seq1.xml","form_type":"4"}},{"id":3890792,"issuer":{"id":46432,"kind":"organization","name":"SOLENO THERAPEUTICS INC","symbol":"SLNO"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Employee stock option (right to buy)","published_at":"2018-06-18T22:14:27.000Z","date":"2018-06-11","kind":"grant","acquired":true,"shares":15931,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"One hundred percent (100%) of the shares subject to the Option shall vest on the one year anniversary on the Vesting Commencement Date (which is June 11, 2018) or the date of the 2018 Annual Shareholder Meeting, whichever is earlier."}],"balance_after":15931,"derivative":{"exercise_price":2.04,"expiration_date":"2028-06-11","underlying":"Common Stock","underlying_shares":15931},"source":{"system":"sec-edgar","filing":"0000899243-18-017052","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1484565/000089924318017052/doc4.xml","form_type":"4"}},{"id":3930465,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2018-05-16T16:05:25.000Z","date":"2018-04-02","kind":"grant","acquired":true,"shares":250000,"price":16,"value":4000000.0,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The securities reported herein are held of record by Vivo Panda Fund, L.P. 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Each of Vivo LLC and Dr. Shah disclaims beneficial ownership of such securities except to the extent of any pecuniary interest therein."}],"balance_after":909742,"source":{"system":"sec-edgar","filing":"0000899243-18-013061","document":"doc4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1255449/000089924318013061/doc4a.xml","form_type":"4/A","original_submission_date":"2018-04-04"}},{"id":3969407,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Series B Preferred Stock","published_at":"2018-04-04T16:45:24.000Z","date":"2018-04-02","kind":"exercise","acquired":false,"shares":659742,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F2","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into one share of the Issuer's common stock."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into one share of the Issuer's common stock."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F2","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into one share of the Issuer's common stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The securities reported herein are held of record by Vivo Panda Fund, L.P. (\"Vivo LP\"). Vivo Panda, LLC (\"Vivo LLC\") is the sole general partner of Vivo LP. Mahendra G. Shah, Ph.D., is a managing member of Vivo LLC and has shared voting and investment power over the securities beneficially owned by Vivo LP and may therefore be deemed to have or share beneficial ownership of the securities held directly by Vivo LP. 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Each of Vivo LLC and Dr. Shah disclaims beneficial ownership of such securities except to the extent of any pecuniary interest therein."}],"balance_after":659742,"source":{"system":"sec-edgar","filing":"0000899243-18-009459","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1255449/000089924318009459/doc4.xml","form_type":"4"}},{"id":3979508,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Employee stock 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vest on the one year anniversary on the Vesting Commencement Date (which is May 8, 2017) or the date of the 2018 Annual Shareholder Meeting, whichever is earlier."}],"balance_after":45139,"derivative":{"exercise_price":0.72,"expiration_date":"2027-05-08","underlying":"Common Stock","underlying_shares":45139},"source":{"system":"sec-edgar","filing":"0000899243-17-012478","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1484565/000089924317012478/doc4.xml","form_type":"4"}},{"id":4352584,"issuer":{"id":46432,"kind":"organization","name":"SOLENO THERAPEUTICS INC","symbol":"SLNO"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2017-04-14T01:44:59.000Z","date":"2017-04-07","kind":"grant","acquired":true,"shares":2533,"price":0.63,"value":1595.79,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Effective January 1, 2017, annual board and committee retainers payable to directors will be made in equivalent shares of the Issuer's common stock, on a quarterly basis."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The number of shares issuable in lieu of cash retainers was determined using the closing price per share of Issuer common stock on April 7, 2017, or $0.63."}],"balance_after":97117,"source":{"system":"sec-edgar","filing":"0000899243-17-010287","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1484565/000089924317010287/doc4.xml","form_type":"4"}},{"id":4392658,"issuer":{"id":46432,"kind":"organization","name":"SOLENO THERAPEUTICS INC","symbol":"SLNO"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Employee Stock Option","published_at":"2017-03-10T02:52:20.000Z","date":"2017-03-07","kind":"grant","acquired":true,"shares":20000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"One forty-eighth (1/48) of the shares subject to the Option shall vest on the first month anniversary of the Vesting Commencement Date (which is March 7, 2017), and shall continue to vest each month thereafter on the same day of the month as the Vesting Commencement Date (and if there is no corresponding day, on the last day of the month), such that all of the shares subject to the Option will have vested as of the fourth anniversary of the Vesting Commencement Date, subject to Participant continuing to be a Service Provider (as defined in the Plan) through each such date."}],"balance_after":20000,"derivative":{"exercise_price":0.68,"expiration_date":"2027-03-07","underlying":"Common Stock","underlying_shares":20000},"source":{"system":"sec-edgar","filing":"0000899243-17-007101","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1484565/000089924317007101/doc4.xml","form_type":"4"}},{"id":4392657,"issuer":{"id":46432,"kind":"organization","name":"SOLENO THERAPEUTICS INC","symbol":"SLNO"},"owners":[{"id":74416,"kind":"person","name":"SHAH MAHENDRA","position":1,"cik":"0001255449","reported_name":"SHAH MAHENDRA","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2017-03-10T02:52:20.000Z","date":"2017-03-07","kind":"grant","acquired":true,"shares":94584,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The reporting person acquired these securities on March 7, 2017, as consideration for the reporting person's interest as a participant in the management carve-out plan of Essentialis, Inc., which was acquired by the Issuer, through a merger of a wholly-owned subsidiary of Issuer with and into Essentialis on March 7, 2017, pursuant to the Agreement and Plan of Merger dated December 22, 2016, by and among the Issuer, Merger Sub (as defined in the Merger Agreement), Essentialis and the Stockholders Representative (as defined therein) (the \"Merger Agreement\")."},{"field":"shares","element":"transactionShares","label":"F2","text":"Continued from Footnote 1\nUnder the terms of the Merger Agreement, a portion of the merger consideration was held back as partial recourse to satisfy indemnification claims made by the Issuer under the Merger Agreement, and such shares will be issued to former shareholders of Essentialis, participants in Essentialis' management carve-out plan and other service providers of Essentialis, upon the one-year anniversary of the closing of the Merger (subject to the limitations set forth in the Merger Agreement)."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"Under the terms of Essentialis' management carve-out plan, the number of shares issuable to carve-out plan participants was determined using the closing price per share of Issuer common stock on March 7, 2017, or $0.68."}],"balance_after":94584,"source":{"system":"sec-edgar","filing":"0000899243-17-007101","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1484565/000089924317007101/doc4.xml","form_type":"4"}}]}