{"transactions":[{"id":976109,"issuer":{"id":5411,"kind":"organization","name":"Ovid Therapeutics Inc."},"owners":[{"id":2662,"kind":"organization","name":"TAKEDA PHARMACEUTICAL CO LTD","symbol":"TAK","position":1,"cik":"0001395064","reported_name":"TAKEDA PHARMACEUTICAL CO LTD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":71983,"kind":"organization","name":"Takeda Pharmaceuticals U.S.A., Inc.","position":2,"cik":"0001716229","reported_name":"Takeda Pharmaceuticals U.S.A., Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A Convertible Preferred Stock","published_at":"2025-12-09T21:19:26.000Z","date":"2025-12-08","kind":"exercise","planned":false,"acquired":false,"shares":1250,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Explanation of Responses"},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Each share of Series A convertible preferred stock (the \"Preferred Stock\") of Ovid Therapeutics Inc. (\"Ovid\") was convertible into 1,000 shares of Ovid's common stock at any time at the election of TPUSA. On December 8, 2025, TPUSA elected to convert all 1,250 shares of Preferred Stock held by TPUSA."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"The Preferred Stock had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reportable securities are directly held by Takeda Pharmaceuticals U.S.A., Inc. (\"TPUSA\"). TPUSA is a direct subsidiary of Takeda Pharmaceuticals International AG. Takeda Pharmaceuticals International AG is a wholly owned subsidiary of Takeda Pharmaceutical Company Limited. As such, Takeda may be deemed to have indirect beneficial ownership of the securities held by TPUSA."}],"balance_after":0,"derivative":{"exercise_price":0,"underlying":"Common Stock","underlying_shares":1250},"source":{"system":"sec-edgar","filing":"0001395064-25-000172","document":"wk-form4_1765333162.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1716229/000139506425000172/wk-form4_1765333162.xml","form_type":"4"}},{"id":976108,"issuer":{"id":5411,"kind":"organization","name":"Ovid Therapeutics Inc."},"owners":[{"id":2662,"kind":"organization","name":"TAKEDA PHARMACEUTICAL CO LTD","symbol":"TAK","position":1,"cik":"0001395064","reported_name":"TAKEDA PHARMACEUTICAL CO LTD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":71983,"kind":"organization","name":"Takeda Pharmaceuticals U.S.A., Inc.","position":2,"cik":"0001716229","reported_name":"Takeda Pharmaceuticals U.S.A., Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-12-09T21:19:26.000Z","date":"2025-12-08","kind":"exercise","planned":false,"acquired":true,"shares":1250000,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Explanation of Responses"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Each share of Series A convertible preferred stock (the \"Preferred Stock\") of Ovid Therapeutics Inc. (\"Ovid\") was convertible into 1,000 shares of Ovid's common stock at any time at the election of TPUSA. On December 8, 2025, TPUSA elected to convert all 1,250 shares of Preferred Stock held by TPUSA."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reportable securities are directly held by Takeda Pharmaceuticals U.S.A., Inc. (\"TPUSA\"). TPUSA is a direct subsidiary of Takeda Pharmaceuticals International AG. Takeda Pharmaceuticals International AG is a wholly owned subsidiary of Takeda Pharmaceutical Company Limited. As such, Takeda may be deemed to have indirect beneficial ownership of the securities held by TPUSA."}],"balance_after":7000000,"source":{"system":"sec-edgar","filing":"0001395064-25-000172","document":"wk-form4_1765333162.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1716229/000139506425000172/wk-form4_1765333162.xml","form_type":"4"}},{"id":2212063,"issuer":{"id":5411,"kind":"organization","name":"Ovid Therapeutics Inc."},"owners":[{"id":2662,"kind":"organization","name":"TAKEDA PHARMACEUTICAL CO LTD","symbol":"TAK","position":1,"cik":"0001395064","reported_name":"TAKEDA PHARMACEUTICAL CO LTD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":71983,"kind":"organization","name":"Takeda Pharmaceuticals U.S.A., Inc.","position":2,"cik":"0001716229","reported_name":"Takeda Pharmaceuticals U.S.A., Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A Convertible Preferred Stock","published_at":"2022-07-06T06:28:15.000Z","date":"2022-07-01","kind":"other","acquired":true,"shares":1250,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Explanation of Responses"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F2","text":"In connection with the Restructuring, Millennium also distributed 1,250 shares of Ovid's Series A convertible preferred stock (the \"Preferred Stock\") to TPUSA. Each share of Preferred Stock is convertible into 1,000 shares of Common Stock at any time at the election of TPUSA, subject to a conversion cap that prevents TPUSA from converting the Preferred Stock if TPUSA or Takeda would beneficially own more than 14.99% of the total number of shares of Common Stock issued and outstanding following such conversion. TPUSA may elect to increase this conversion cap to up to 19.99% of the total number of shares of Common Stock by providing 61 days' written notice to the issuer."},{"field":"shares","element":"transactionShares","label":"F2","text":"In connection with the Restructuring, Millennium also distributed 1,250 shares of Ovid's Series A convertible preferred stock (the \"Preferred Stock\") to TPUSA. Each share of Preferred Stock is convertible into 1,000 shares of Common Stock at any time at the election of TPUSA, subject to a conversion cap that prevents TPUSA from converting the Preferred Stock if TPUSA or Takeda would beneficially own more than 14.99% of the total number of shares of Common Stock issued and outstanding following such conversion. TPUSA may elect to increase this conversion cap to up to 19.99% of the total number of shares of Common Stock by providing 61 days' written notice to the issuer."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"In connection with the Restructuring, Millennium also distributed 1,250 shares of Ovid's Series A convertible preferred stock (the \"Preferred Stock\") to TPUSA. Each share of Preferred Stock is convertible into 1,000 shares of Common Stock at any time at the election of TPUSA, subject to a conversion cap that prevents TPUSA from converting the Preferred Stock if TPUSA or Takeda would beneficially own more than 14.99% of the total number of shares of Common Stock issued and outstanding following such conversion. TPUSA may elect to increase this conversion cap to up to 19.99% of the total number of shares of Common Stock by providing 61 days' written notice to the issuer."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"The Preferred Stock has no expiration date."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"In connection with the Restructuring, Millennium also distributed 1,250 shares of Ovid's Series A convertible preferred stock (the \"Preferred Stock\") to TPUSA. Each share of Preferred Stock is convertible into 1,000 shares of Common Stock at any time at the election of TPUSA, subject to a conversion cap that prevents TPUSA from converting the Preferred Stock if TPUSA or Takeda would beneficially own more than 14.99% of the total number of shares of Common Stock issued and outstanding following such conversion. TPUSA may elect to increase this conversion cap to up to 19.99% of the total number of shares of Common Stock by providing 61 days' written notice to the issuer."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"On July 1, 2022, the reporting persons effected an internal reorganization (the \"Restructuring\") whereby Millennium Pharmaceuticals, Inc. (\"Millennium\"), a wholly owned subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"TPUSA\"), distributed its shares of Ovid Therapeutics Inc.'s (\"Ovid\") common stock (the \"Common Stock\") to TPUSA. TPUSA is a direct subsidiary of Takeda Pharmaceutical Company Limited (\"Takeda\") (72.70%) and Takeda Pharmaceuticals International AG (27.30%). Takeda Pharmaceuticals International AG is a wholly owned subsidiary of Takeda. As such, Takeda is an indirect beneficial owner of the securities held by TPUSA, and its ownership remains unchanged from the Restructuring, including the 1,781,996 shares of Common Stock held directly by Takeda. No additional consideration was paid as part of the distribution of the Common Stock from Millennium to TPUSA."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"In connection with the Restructuring, Millennium also distributed 1,250 shares of Ovid's Series A convertible preferred stock (the \"Preferred Stock\") to TPUSA. Each share of Preferred Stock is convertible into 1,000 shares of Common Stock at any time at the election of TPUSA, subject to a conversion cap that prevents TPUSA from converting the Preferred Stock if TPUSA or Takeda would beneficially own more than 14.99% of the total number of shares of Common Stock issued and outstanding following such conversion. TPUSA may elect to increase this conversion cap to up to 19.99% of the total number of shares of Common Stock by providing 61 days' written notice to the issuer."}],"balance_after":1250,"derivative":{"exercise_price":0,"underlying":"Common Stock","underlying_shares":1250000},"source":{"system":"sec-edgar","filing":"0001395064-22-000121","document":"wf-form4_165710328185839.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1716229/000139506422000121/wf-form4_165710328185839.xml","form_type":"4"}},{"id":2212062,"issuer":{"id":5411,"kind":"organization","name":"Ovid Therapeutics Inc."},"owners":[{"id":2662,"kind":"organization","name":"TAKEDA PHARMACEUTICAL CO LTD","symbol":"TAK","position":1,"cik":"0001395064","reported_name":"TAKEDA PHARMACEUTICAL CO LTD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":71983,"kind":"organization","name":"Takeda Pharmaceuticals U.S.A., Inc.","position":2,"cik":"0001716229","reported_name":"Takeda Pharmaceuticals U.S.A., Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A Convertible Preferred Stock","published_at":"2022-07-06T06:28:15.000Z","date":"2022-07-01","kind":"other","acquired":false,"shares":1250,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Explanation of Responses"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F2","text":"In connection with the Restructuring, Millennium also distributed 1,250 shares of Ovid's Series A convertible preferred stock (the \"Preferred Stock\") to TPUSA. Each share of Preferred Stock is convertible into 1,000 shares of Common Stock at any time at the election of TPUSA, subject to a conversion cap that prevents TPUSA from converting the Preferred Stock if TPUSA or Takeda would beneficially own more than 14.99% of the total number of shares of Common Stock issued and outstanding following such conversion. TPUSA may elect to increase this conversion cap to up to 19.99% of the total number of shares of Common Stock by providing 61 days' written notice to the issuer."},{"field":"shares","element":"transactionShares","label":"F2","text":"In connection with the Restructuring, Millennium also distributed 1,250 shares of Ovid's Series A convertible preferred stock (the \"Preferred Stock\") to TPUSA. Each share of Preferred Stock is convertible into 1,000 shares of Common Stock at any time at the election of TPUSA, subject to a conversion cap that prevents TPUSA from converting the Preferred Stock if TPUSA or Takeda would beneficially own more than 14.99% of the total number of shares of Common Stock issued and outstanding following such conversion. TPUSA may elect to increase this conversion cap to up to 19.99% of the total number of shares of Common Stock by providing 61 days' written notice to the issuer."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"In connection with the Restructuring, Millennium also distributed 1,250 shares of Ovid's Series A convertible preferred stock (the \"Preferred Stock\") to TPUSA. Each share of Preferred Stock is convertible into 1,000 shares of Common Stock at any time at the election of TPUSA, subject to a conversion cap that prevents TPUSA from converting the Preferred Stock if TPUSA or Takeda would beneficially own more than 14.99% of the total number of shares of Common Stock issued and outstanding following such conversion. TPUSA may elect to increase this conversion cap to up to 19.99% of the total number of shares of Common Stock by providing 61 days' written notice to the issuer."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"The Preferred Stock has no expiration date."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"In connection with the Restructuring, Millennium also distributed 1,250 shares of Ovid's Series A convertible preferred stock (the \"Preferred Stock\") to TPUSA. Each share of Preferred Stock is convertible into 1,000 shares of Common Stock at any time at the election of TPUSA, subject to a conversion cap that prevents TPUSA from converting the Preferred Stock if TPUSA or Takeda would beneficially own more than 14.99% of the total number of shares of Common Stock issued and outstanding following such conversion. TPUSA may elect to increase this conversion cap to up to 19.99% of the total number of shares of Common Stock by providing 61 days' written notice to the issuer."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"On July 1, 2022, the reporting persons effected an internal reorganization (the \"Restructuring\") whereby Millennium Pharmaceuticals, Inc. (\"Millennium\"), a wholly owned subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"TPUSA\"), distributed its shares of Ovid Therapeutics Inc.'s (\"Ovid\") common stock (the \"Common Stock\") to TPUSA. TPUSA is a direct subsidiary of Takeda Pharmaceutical Company Limited (\"Takeda\") (72.70%) and Takeda Pharmaceuticals International AG (27.30%). Takeda Pharmaceuticals International AG is a wholly owned subsidiary of Takeda. As such, Takeda is an indirect beneficial owner of the securities held by TPUSA, and its ownership remains unchanged from the Restructuring, including the 1,781,996 shares of Common Stock held directly by Takeda. No additional consideration was paid as part of the distribution of the Common Stock from Millennium to TPUSA."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"In connection with the Restructuring, Millennium also distributed 1,250 shares of Ovid's Series A convertible preferred stock (the \"Preferred Stock\") to TPUSA. Each share of Preferred Stock is convertible into 1,000 shares of Common Stock at any time at the election of TPUSA, subject to a conversion cap that prevents TPUSA from converting the Preferred Stock if TPUSA or Takeda would beneficially own more than 14.99% of the total number of shares of Common Stock issued and outstanding following such conversion. TPUSA may elect to increase this conversion cap to up to 19.99% of the total number of shares of Common Stock by providing 61 days' written notice to the issuer."}],"balance_after":0,"derivative":{"exercise_price":0,"underlying":"Common Stock","underlying_shares":1250000},"source":{"system":"sec-edgar","filing":"0001395064-22-000121","document":"wf-form4_165710328185839.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1716229/000139506422000121/wf-form4_165710328185839.xml","form_type":"4"}},{"id":2212061,"issuer":{"id":5411,"kind":"organization","name":"Ovid Therapeutics Inc."},"owners":[{"id":2662,"kind":"organization","name":"TAKEDA PHARMACEUTICAL CO LTD","symbol":"TAK","position":1,"cik":"0001395064","reported_name":"TAKEDA PHARMACEUTICAL CO LTD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":71983,"kind":"organization","name":"Takeda Pharmaceuticals U.S.A., Inc.","position":2,"cik":"0001716229","reported_name":"Takeda Pharmaceuticals U.S.A., Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2022-07-06T06:28:15.000Z","date":"2022-07-01","kind":"other","acquired":true,"shares":5750000,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Explanation of Responses"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"On July 1, 2022, the reporting persons effected an internal reorganization (the \"Restructuring\") whereby Millennium Pharmaceuticals, Inc. (\"Millennium\"), a wholly owned subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"TPUSA\"), distributed its shares of Ovid Therapeutics Inc.'s (\"Ovid\") common stock (the \"Common Stock\") to TPUSA. TPUSA is a direct subsidiary of Takeda Pharmaceutical Company Limited (\"Takeda\") (72.70%) and Takeda Pharmaceuticals International AG (27.30%). Takeda Pharmaceuticals International AG is a wholly owned subsidiary of Takeda. As such, Takeda is an indirect beneficial owner of the securities held by TPUSA, and its ownership remains unchanged from the Restructuring, including the 1,781,996 shares of Common Stock held directly by Takeda. No additional consideration was paid as part of the distribution of the Common Stock from Millennium to TPUSA."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On July 1, 2022, the reporting persons effected an internal reorganization (the \"Restructuring\") whereby Millennium Pharmaceuticals, Inc. (\"Millennium\"), a wholly owned subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"TPUSA\"), distributed its shares of Ovid Therapeutics Inc.'s (\"Ovid\") common stock (the \"Common Stock\") to TPUSA. TPUSA is a direct subsidiary of Takeda Pharmaceutical Company Limited (\"Takeda\") (72.70%) and Takeda Pharmaceuticals International AG (27.30%). Takeda Pharmaceuticals International AG is a wholly owned subsidiary of Takeda. As such, Takeda is an indirect beneficial owner of the securities held by TPUSA, and its ownership remains unchanged from the Restructuring, including the 1,781,996 shares of Common Stock held directly by Takeda. No additional consideration was paid as part of the distribution of the Common Stock from Millennium to TPUSA."},{"field":"acquired","element":"transactionAcquiredDisposedCode","label":"F1","text":"On July 1, 2022, the reporting persons effected an internal reorganization (the \"Restructuring\") whereby Millennium Pharmaceuticals, Inc. (\"Millennium\"), a wholly owned subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"TPUSA\"), distributed its shares of Ovid Therapeutics Inc.'s (\"Ovid\") common stock (the \"Common Stock\") to TPUSA. TPUSA is a direct subsidiary of Takeda Pharmaceutical Company Limited (\"Takeda\") (72.70%) and Takeda Pharmaceuticals International AG (27.30%). Takeda Pharmaceuticals International AG is a wholly owned subsidiary of Takeda. As such, Takeda is an indirect beneficial owner of the securities held by TPUSA, and its ownership remains unchanged from the Restructuring, including the 1,781,996 shares of Common Stock held directly by Takeda. No additional consideration was paid as part of the distribution of the Common Stock from Millennium to TPUSA."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"On July 1, 2022, the reporting persons effected an internal reorganization (the \"Restructuring\") whereby Millennium Pharmaceuticals, Inc. (\"Millennium\"), a wholly owned subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"TPUSA\"), distributed its shares of Ovid Therapeutics Inc.'s (\"Ovid\") common stock (the \"Common Stock\") to TPUSA. TPUSA is a direct subsidiary of Takeda Pharmaceutical Company Limited (\"Takeda\") (72.70%) and Takeda Pharmaceuticals International AG (27.30%). Takeda Pharmaceuticals International AG is a wholly owned subsidiary of Takeda. As such, Takeda is an indirect beneficial owner of the securities held by TPUSA, and its ownership remains unchanged from the Restructuring, including the 1,781,996 shares of Common Stock held directly by Takeda. No additional consideration was paid as part of the distribution of the Common Stock from Millennium to TPUSA."}],"balance_after":5750000,"source":{"system":"sec-edgar","filing":"0001395064-22-000121","document":"wf-form4_165710328185839.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1716229/000139506422000121/wf-form4_165710328185839.xml","form_type":"4"}},{"id":2212060,"issuer":{"id":5411,"kind":"organization","name":"Ovid Therapeutics Inc."},"owners":[{"id":2662,"kind":"organization","name":"TAKEDA PHARMACEUTICAL CO LTD","symbol":"TAK","position":1,"cik":"0001395064","reported_name":"TAKEDA PHARMACEUTICAL CO LTD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":71983,"kind":"organization","name":"Takeda Pharmaceuticals U.S.A., Inc.","position":2,"cik":"0001716229","reported_name":"Takeda Pharmaceuticals U.S.A., Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2022-07-06T06:28:15.000Z","date":"2022-07-01","kind":"other","acquired":false,"shares":5750000,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Explanation of Responses"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"On July 1, 2022, the reporting persons effected an internal reorganization (the \"Restructuring\") whereby Millennium Pharmaceuticals, Inc. (\"Millennium\"), a wholly owned subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"TPUSA\"), distributed its shares of Ovid Therapeutics Inc.'s (\"Ovid\") common stock (the \"Common Stock\") to TPUSA. TPUSA is a direct subsidiary of Takeda Pharmaceutical Company Limited (\"Takeda\") (72.70%) and Takeda Pharmaceuticals International AG (27.30%). Takeda Pharmaceuticals International AG is a wholly owned subsidiary of Takeda. As such, Takeda is an indirect beneficial owner of the securities held by TPUSA, and its ownership remains unchanged from the Restructuring, including the 1,781,996 shares of Common Stock held directly by Takeda. No additional consideration was paid as part of the distribution of the Common Stock from Millennium to TPUSA."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On July 1, 2022, the reporting persons effected an internal reorganization (the \"Restructuring\") whereby Millennium Pharmaceuticals, Inc. (\"Millennium\"), a wholly owned subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"TPUSA\"), distributed its shares of Ovid Therapeutics Inc.'s (\"Ovid\") common stock (the \"Common Stock\") to TPUSA. TPUSA is a direct subsidiary of Takeda Pharmaceutical Company Limited (\"Takeda\") (72.70%) and Takeda Pharmaceuticals International AG (27.30%). Takeda Pharmaceuticals International AG is a wholly owned subsidiary of Takeda. As such, Takeda is an indirect beneficial owner of the securities held by TPUSA, and its ownership remains unchanged from the Restructuring, including the 1,781,996 shares of Common Stock held directly by Takeda. No additional consideration was paid as part of the distribution of the Common Stock from Millennium to TPUSA."},{"field":"acquired","element":"transactionAcquiredDisposedCode","label":"F1","text":"On July 1, 2022, the reporting persons effected an internal reorganization (the \"Restructuring\") whereby Millennium Pharmaceuticals, Inc. (\"Millennium\"), a wholly owned subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"TPUSA\"), distributed its shares of Ovid Therapeutics Inc.'s (\"Ovid\") common stock (the \"Common Stock\") to TPUSA. TPUSA is a direct subsidiary of Takeda Pharmaceutical Company Limited (\"Takeda\") (72.70%) and Takeda Pharmaceuticals International AG (27.30%). Takeda Pharmaceuticals International AG is a wholly owned subsidiary of Takeda. As such, Takeda is an indirect beneficial owner of the securities held by TPUSA, and its ownership remains unchanged from the Restructuring, including the 1,781,996 shares of Common Stock held directly by Takeda. No additional consideration was paid as part of the distribution of the Common Stock from Millennium to TPUSA."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"On July 1, 2022, the reporting persons effected an internal reorganization (the \"Restructuring\") whereby Millennium Pharmaceuticals, Inc. (\"Millennium\"), a wholly owned subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"TPUSA\"), distributed its shares of Ovid Therapeutics Inc.'s (\"Ovid\") common stock (the \"Common Stock\") to TPUSA. TPUSA is a direct subsidiary of Takeda Pharmaceutical Company Limited (\"Takeda\") (72.70%) and Takeda Pharmaceuticals International AG (27.30%). Takeda Pharmaceuticals International AG is a wholly owned subsidiary of Takeda. As such, Takeda is an indirect beneficial owner of the securities held by TPUSA, and its ownership remains unchanged from the Restructuring, including the 1,781,996 shares of Common Stock held directly by Takeda. No additional consideration was paid as part of the distribution of the Common Stock from Millennium to TPUSA."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001395064-22-000121","document":"wf-form4_165710328185839.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1716229/000139506422000121/wf-form4_165710328185839.xml","form_type":"4"}},{"id":2479580,"issuer":{"id":51180,"kind":"organization","name":"Day One Biopharmaceuticals, Inc.","symbol":"DAWN"},"owners":[{"id":2662,"kind":"organization","name":"TAKEDA PHARMACEUTICAL CO LTD","symbol":"TAK","position":1,"cik":"0001395064","reported_name":"TAKEDA PHARMACEUTICAL CO LTD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":71983,"kind":"organization","name":"Takeda Pharmaceuticals U.S.A., Inc.","position":2,"cik":"0001716229","reported_name":"Takeda Pharmaceuticals U.S.A., Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":127918,"kind":"organization","name":"MILLENNIUM PHARMACEUTICALS INC","position":3,"cik":"0001002637","reported_name":"MILLENNIUM PHARMACEUTICALS INC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113074,"kind":"organization","name":"Takeda Ventures, Inc.","position":4,"cik":"0001771657","reported_name":"Takeda Ventures, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-12-09T06:04:25.000Z","date":"2021-12-08","kind":"sale","acquired":false,"shares":110338,"price":18.03,"value":1989394.14,"ownership":{"direct":false,"nature":"See Explanation of Responses"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F6","text":"Reflects the weighted average sale price.  This transaction was executed in multiple trades at prices ranging from $18.00 to $18.47.  Information regarding the number of shares sold at each separate price will be provided upon request by the Staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"This statement is being filed jointly by Takeda Pharmaceutical Company Limited, Takeda Pharmaceuticals U.S.A. Inc., Millennium Pharmaceuticals, Inc. and Takeda Ventures, Inc."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Takeda Pharmaceutical Company Limiteds beneficial ownership of the reported securities is comprised of 6,062,900 shares of Common Stock held by Millennium Pharmaceuticals, Inc. and 57,224 shares of Common Stock held by Takeda Ventures, Inc.  Millennium Pharmaceuticals, Inc. and Takeda Ventures, Inc. are each direct, wholly owned subsidiaries of Takeda Pharmaceuticals U.S.A. Inc., which is a direct subsidiary of Takeda Pharmaceutical Company Limited (72.70%) and Takeda Pharmaceuticals International AG (27.3%)."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Takeda Pharmaceuticals International AG is a direct, wholly owned subsidiary of Takeda Pharmaceutical Company Limited. Each of Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals U.S.A. Inc. may be deemed to share voting and dispositive power over the shares held by Takeda Ventures, Inc. and Millennium Pharmaceuticals, Inc. Each of Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals U.S.A. Inc. disclaims beneficial ownership of the shares held by Takeda Ventures, Inc. and Millennium Pharmaceuticals, Inc. except to the extent of their pecuniary interests therein."}],"balance_after":6120124,"source":{"system":"sec-edgar","filing":"0001395064-21-000248","document":"wf-form4_163904785164853.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1002637/000139506421000248/wf-form4_163904785164853.xml","form_type":"4"}},{"id":2479579,"issuer":{"id":51180,"kind":"organization","name":"Day One Biopharmaceuticals, Inc.","symbol":"DAWN"},"owners":[{"id":2662,"kind":"organization","name":"TAKEDA PHARMACEUTICAL CO LTD","symbol":"TAK","position":1,"cik":"0001395064","reported_name":"TAKEDA PHARMACEUTICAL CO LTD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":71983,"kind":"organization","name":"Takeda Pharmaceuticals U.S.A., Inc.","position":2,"cik":"0001716229","reported_name":"Takeda Pharmaceuticals U.S.A., Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":127918,"kind":"organization","name":"MILLENNIUM PHARMACEUTICALS INC","position":3,"cik":"0001002637","reported_name":"MILLENNIUM PHARMACEUTICALS INC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113074,"kind":"organization","name":"Takeda Ventures, Inc.","position":4,"cik":"0001771657","reported_name":"Takeda Ventures, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-12-09T06:04:25.000Z","date":"2021-12-07","kind":"sale","acquired":false,"shares":58190,"price":19.5,"value":1134705.0,"ownership":{"direct":false,"nature":"See Explanation of Responses"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F5","text":"Reflects the weighted average sale price.  This transaction was executed in multiple trades at prices ranging from $19.00 to $19.88.  Information regarding the number of shares sold at each separate price will be provided upon request by the Staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"This statement is being filed jointly by Takeda Pharmaceutical Company Limited, Takeda Pharmaceuticals U.S.A. Inc., Millennium Pharmaceuticals, Inc. and Takeda Ventures, Inc."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Takeda Pharmaceutical Company Limiteds beneficial ownership of the reported securities is comprised of 6,062,900 shares of Common Stock held by Millennium Pharmaceuticals, Inc. and 57,224 shares of Common Stock held by Takeda Ventures, Inc.  Millennium Pharmaceuticals, Inc. and Takeda Ventures, Inc. are each direct, wholly owned subsidiaries of Takeda Pharmaceuticals U.S.A. Inc., which is a direct subsidiary of Takeda Pharmaceutical Company Limited (72.70%) and Takeda Pharmaceuticals International AG (27.3%)."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Takeda Pharmaceuticals International AG is a direct, wholly owned subsidiary of Takeda Pharmaceutical Company Limited. Each of Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals U.S.A. Inc. may be deemed to share voting and dispositive power over the shares held by Takeda Ventures, Inc. and Millennium Pharmaceuticals, Inc. Each of Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals U.S.A. 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This transaction was executed in multiple trades at prices ranging from $18.00 to $18.97.  Information regarding the number of shares sold at each separate price will be provided upon request by the Staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"This statement is being filed jointly by Takeda Pharmaceutical Company Limited, Takeda Pharmaceuticals U.S.A. Inc., Millennium Pharmaceuticals, Inc. and Takeda Ventures, Inc."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Takeda Pharmaceutical Company Limiteds beneficial ownership of the reported securities is comprised of 6,062,900 shares of Common Stock held by Millennium Pharmaceuticals, Inc. and 57,224 shares of Common Stock held by Takeda Ventures, Inc.  Millennium Pharmaceuticals, Inc. and Takeda Ventures, Inc. are each direct, wholly owned subsidiaries of Takeda Pharmaceuticals U.S.A. Inc., which is a direct subsidiary of Takeda Pharmaceutical Company Limited (72.70%) and Takeda Pharmaceuticals International AG (27.3%)."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Takeda Pharmaceuticals International AG is a direct, wholly owned subsidiary of Takeda Pharmaceutical Company Limited. Each of Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals U.S.A. Inc. may be deemed to share voting and dispositive power over the shares held by Takeda Ventures, Inc. and Millennium Pharmaceuticals, Inc. Each of Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals U.S.A. Inc. disclaims beneficial ownership of the shares held by Takeda Ventures, Inc. and Millennium Pharmaceuticals, Inc. except to the extent of their pecuniary interests therein."}],"balance_after":6288652,"source":{"system":"sec-edgar","filing":"0001395064-21-000248","document":"wf-form4_163904785164853.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1002637/000139506421000248/wf-form4_163904785164853.xml","form_type":"4"}},{"id":2482965,"issuer":{"id":51180,"kind":"organization","name":"Day One Biopharmaceuticals, Inc.","symbol":"DAWN"},"owners":[{"id":2662,"kind":"organization","name":"TAKEDA PHARMACEUTICAL CO LTD","symbol":"TAK","position":1,"cik":"0001395064","reported_name":"TAKEDA PHARMACEUTICAL CO LTD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":71983,"kind":"organization","name":"Takeda Pharmaceuticals U.S.A., Inc.","position":2,"cik":"0001716229","reported_name":"Takeda Pharmaceuticals U.S.A., Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":127918,"kind":"organization","name":"MILLENNIUM PHARMACEUTICALS INC","position":3,"cik":"0001002637","reported_name":"MILLENNIUM PHARMACEUTICALS INC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113074,"kind":"organization","name":"Takeda Ventures, Inc.","position":4,"cik":"0001771657","reported_name":"Takeda Ventures, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-12-07T06:01:34.000Z","date":"2021-12-06","kind":"sale","acquired":false,"shares":97692,"price":18.05,"value":1763340.6,"ownership":{"direct":false,"nature":"See Explanation of Responses"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F5","text":"Reflects the weighted average sale price.  This transaction was executed in multiple trades at prices ranging from $18.00 to $18.27.  Information regarding the number of shares sold at each separate price will be provided upon request by the Staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"This statement is being filed jointly by Takeda Pharmaceutical Company Limited, Takeda Pharmaceuticals U.S.A. Inc., Millennium Pharmaceuticals, Inc. and Takeda Ventures, Inc."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Takeda Pharmaceutical Company Limiteds beneficial ownership of the reported securities is comprised of 6,360,173 shares of Common Stock held by Millennium Pharmaceuticals, Inc. and 57,224 shares of Common Stock held by Takeda Ventures, Inc.  Millennium Pharmaceuticals, Inc. and Takeda Ventures, Inc. are each direct, wholly owned subsidiaries of Takeda Pharmaceuticals U.S.A. Inc., which is a direct subsidiary of Takeda Pharmaceutical Company Limited (72.70%) and Takeda Pharmaceuticals International AG (27.3%)."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Takeda Pharmaceuticals International AG is a direct, wholly owned subsidiary of Takeda Pharmaceutical Company Limited. Each of Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals U.S.A. Inc. may be deemed to share voting and dispositive power over the shares held by Takeda Ventures, Inc. and Millennium Pharmaceuticals, Inc. Each of Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals U.S.A. 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This transaction was executed in multiple trades at prices ranging from $18.10 to $18.78.  Information regarding the number of shares sold at each separate price will be provided upon request by the Staff of the Securities and Exchange Commission, the Issuer or any security holder of the Issuer."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"This statement is being filed jointly by Takeda Pharmaceutical Company Limited, Takeda Pharmaceuticals U.S.A. Inc., Millennium Pharmaceuticals, Inc. and Takeda Ventures, Inc."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Takeda Pharmaceutical Company Limiteds beneficial ownership of the reported securities is comprised of 6,360,173 shares of Common Stock held by Millennium Pharmaceuticals, Inc. and 57,224 shares of Common Stock held by Takeda Ventures, Inc.  Millennium Pharmaceuticals, Inc. and Takeda Ventures, Inc. are each direct, wholly owned subsidiaries of Takeda Pharmaceuticals U.S.A. Inc., which is a direct subsidiary of Takeda Pharmaceutical Company Limited (72.70%) and Takeda Pharmaceuticals International AG (27.3%)."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Takeda Pharmaceuticals International AG is a direct, wholly owned subsidiary of Takeda Pharmaceutical Company Limited. Each of Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals U.S.A. Inc. may be deemed to share voting and dispositive power over the shares held by Takeda Ventures, Inc. and Millennium Pharmaceuticals, Inc. Each of Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals U.S.A. 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Takeda Ventures, Inc. is a limited partner of Atlas Venture Fund XI, L.P. The distribution was a pro-rata distribution, and not a purchase or sale, without any consideration paid by Takeda Ventures, Inc."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"This statement is being filed jointly by Takeda Pharmaceutical Company Limited, Takeda Pharmaceuticals U.S.A. Inc., Millennium Pharmaceuticals, Inc. and Takeda Ventures, Inc."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Takeda Pharmaceutical Company Limited's beneficial ownership of the reported securities is comprised of 6,470,382 shares of Common Stock held by Millennium Pharmaceuticals, Inc. and 57,224 shares of Common Stock held by Takeda Ventures, Inc.  Millennium Pharmaceuticals, Inc. and Takeda Ventures, Inc. are each direct, wholly owned subsidiaries of Takeda Pharmaceuticals U.S.A. Inc., which is a direct subsidiary of Takeda Pharmaceutical Company Limited (72.70%) and Takeda Pharmaceuticals International AG (27.3%)."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Takeda Pharmaceuticals International AG is a direct, wholly owned subsidiary of Takeda Pharmaceutical Company Limited. Each of Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals U.S.A. Inc. may be deemed to share voting and dispositive power over the shares held by Takeda Ventures, Inc. and Millennium Pharmaceuticals, Inc. Each of Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals U.S.A. 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The Redeemable Convertible Preferred Stock had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"Each share of Series A Redeemable Convertible Preferred Stock and each share of Series B Redeemable Convertible Preferred Stock automatically converted into one share of Issuer's Common Stock, respectively, for no additional consideration at the completion of the Issuer's initial public offering. The Redeemable Convertible Preferred Stock had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F2","text":"Each share of Series A Redeemable Convertible Preferred Stock and each share of Series B Redeemable Convertible Preferred Stock automatically converted into one share of Issuer's Common Stock, respectively, for no additional consideration at the completion of the Issuer's initial public offering. The Redeemable Convertible Preferred Stock had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"These shares are owned directly by Takeda Ventures, Inc. Takeda Ventures, Inc. is a wholly-owned direct subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"Takeda USA\"). Takeda Pharmaceuticals International AG owns 41.91% of Takeda USA, and Takeda Pharmaceutical Company Limited owns 58.09% of Takeda USA.  Takeda Pharmaceuticals International AG is a wholly-owned direct subsidiary of Takeda Pharmaceutical Company Limited."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":319731},"source":{"system":"sec-edgar","filing":"0001209191-19-029480","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1716229/000120919119029480/doc4.xml","form_type":"4"}},{"id":3530055,"issuer":{"id":7403,"kind":"organization","name":"Quince Therapeutics, Inc."},"owners":[{"id":113074,"kind":"organization","name":"Takeda Ventures, Inc.","position":1,"cik":"0001771657","reported_name":"Takeda Ventures, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":2662,"kind":"organization","name":"TAKEDA PHARMACEUTICAL CO LTD","symbol":"TAK","position":2,"cik":"0001395064","reported_name":"TAKEDA PHARMACEUTICAL CO LTD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157677,"kind":"organization","name":"Takeda Pharmaceuticals International AG","position":3,"cik":"0001688140","reported_name":"Takeda Pharmaceuticals International AG","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":71983,"kind":"organization","name":"Takeda Pharmaceuticals U.S.A., Inc.","position":4,"cik":"0001716229","reported_name":"Takeda Pharmaceuticals U.S.A., Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A Redeemable Convertible Preferred Stock","published_at":"2019-05-13T19:52:46.000Z","date":"2019-05-13","kind":"exercise","acquired":false,"shares":2360071,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F2","text":"Each share of Series A Redeemable Convertible Preferred Stock and each share of Series B Redeemable Convertible Preferred Stock automatically converted into one share of Issuer's Common Stock, respectively, for no additional consideration at the completion of the Issuer's initial public offering. The Redeemable Convertible Preferred Stock had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"Each share of Series A Redeemable Convertible Preferred Stock and each share of Series B Redeemable Convertible Preferred Stock automatically converted into one share of Issuer's Common Stock, respectively, for no additional consideration at the completion of the Issuer's initial public offering. The Redeemable Convertible Preferred Stock had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F2","text":"Each share of Series A Redeemable Convertible Preferred Stock and each share of Series B Redeemable Convertible Preferred Stock automatically converted into one share of Issuer's Common Stock, respectively, for no additional consideration at the completion of the Issuer's initial public offering. The Redeemable Convertible Preferred Stock had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"These shares are owned directly by Takeda Ventures, Inc. Takeda Ventures, Inc. is a wholly-owned direct subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"Takeda USA\"). Takeda Pharmaceuticals International AG owns 41.91% of Takeda USA, and Takeda Pharmaceutical Company Limited owns 58.09% of Takeda USA.  Takeda Pharmaceuticals International AG is a wholly-owned direct subsidiary of Takeda Pharmaceutical Company Limited."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":2360071},"source":{"system":"sec-edgar","filing":"0001209191-19-029480","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1716229/000120919119029480/doc4.xml","form_type":"4"}},{"id":3530054,"issuer":{"id":7403,"kind":"organization","name":"Quince Therapeutics, Inc."},"owners":[{"id":113074,"kind":"organization","name":"Takeda Ventures, Inc.","position":1,"cik":"0001771657","reported_name":"Takeda Ventures, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":2662,"kind":"organization","name":"TAKEDA PHARMACEUTICAL CO LTD","symbol":"TAK","position":2,"cik":"0001395064","reported_name":"TAKEDA PHARMACEUTICAL CO LTD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157677,"kind":"organization","name":"Takeda Pharmaceuticals International AG","position":3,"cik":"0001688140","reported_name":"Takeda Pharmaceuticals International AG","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":71983,"kind":"organization","name":"Takeda Pharmaceuticals U.S.A., Inc.","position":4,"cik":"0001716229","reported_name":"Takeda Pharmaceuticals U.S.A., Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2019-05-13T19:52:46.000Z","date":"2019-05-13","kind":"exercise","acquired":true,"shares":2679802,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The total represents shares received upon conversion of shares of Series A Redeemable Convertible Preferred Stock and shares of Series B Redeemable Convertible Preferred Stock."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"Each share of Series A Redeemable Convertible Preferred Stock and each share of Series B Redeemable Convertible Preferred Stock automatically converted into one share of Issuer's Common Stock, respectively, for no additional consideration at the completion of the Issuer's initial public offering. The Redeemable Convertible Preferred Stock had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"These shares are owned directly by Takeda Ventures, Inc. Takeda Ventures, Inc. is a wholly-owned direct subsidiary of Takeda Pharmaceuticals U.S.A., Inc. (\"Takeda USA\"). Takeda Pharmaceuticals International AG owns 41.91% of Takeda USA, and Takeda Pharmaceutical Company Limited owns 58.09% of Takeda USA.  Takeda Pharmaceuticals International AG is a wholly-owned direct subsidiary of Takeda Pharmaceutical Company Limited."}],"balance_after":2679802,"source":{"system":"sec-edgar","filing":"0001209191-19-029480","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1716229/000120919119029480/doc4.xml","form_type":"4"}}]}