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The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price."}],"balance_after":14500,"source":{"system":"sec-edgar","filing":"0001415889-24-028287","document":"form4-12042024_051205.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1070081/000141588924028287/form4-12042024_051205.xml","form_type":"4"}},{"id":1343556,"issuer":{"id":3803,"kind":"organization","name":"PTC THERAPEUTICS, INC.","symbol":"PTCT"},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME B","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2024-12-04T22:20:10.000Z","date":"2024-12-02","kind":"sale","planned":true,"acquired":false,"shares":8813,"price":51.44,"value":453340.72,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on May 22, 2024"},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"This price represents the weighted average price of sale transactions that were executed in multiple trades at prices ranging from $51.10 to $52.09 per share. The Reporting Person hereby undertakes, upon request by the SEC staff, the issuer or a security holder of the issuer, to provide full information regarding the number of shares sold at each separate price."}],"balance_after":17687,"source":{"system":"sec-edgar","filing":"0001415889-24-028287","document":"form4-12042024_051205.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1070081/000141588924028287/form4-12042024_051205.xml","form_type":"4"}},{"id":1343555,"issuer":{"id":3803,"kind":"organization","name":"PTC THERAPEUTICS, INC.","symbol":"PTCT"},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME B","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2024-12-04T22:20:10.000Z","date":"2024-12-02","kind":"exercise","planned":true,"acquired":true,"shares":12000,"price":51,"value":612000.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was effected pursuant to a written Rule 10b5-1 plan adopted by the Reporting Person on May 22, 2024"}],"balance_after":26500,"source":{"system":"sec-edgar","filing":"0001415889-24-028287","document":"form4-12042024_051205.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1070081/000141588924028287/form4-12042024_051205.xml","form_type":"4"}},{"id":1354181,"issuer":{"id":8400,"kind":"organization","name":"NEXGEL, INC."},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME B","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Warrant to Purchase Common Stock","published_at":"2024-11-22T21:54:12.000Z","date":"2024-11-20","kind":"grant","planned":false,"acquired":true,"shares":1818,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The Reporting Person acquired the shares of common stock and warrant to purchase common stock reported on this Form 4 in connection with the Issuer's registered direct offering. The Reporting Person agreed not to offer, issue, sell, contract to sell, encumber, grant any option for the sale of or otherwise dispose of any of the shares of common stock and the shares of common stock underlying the warrant for a period of 180 days following November 20, 2024."}],"balance_after":1818,"derivative":{"exercise_price":4.25,"exercise_date":"2024-11-20","expiration_date":"2029-11-20","underlying":"Common Stock","underlying_shares":1818},"source":{"system":"sec-edgar","filing":"0001493152-24-047434","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1468929/000149315224047434/ownership.xml","form_type":"4"}},{"id":1354180,"issuer":{"id":8400,"kind":"organization","name":"NEXGEL, INC."},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME B","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2024-11-22T21:54:12.000Z","date":"2024-11-20","kind":"purchase","planned":false,"acquired":true,"shares":3636,"price":2.75,"value":9999.0,"ownership":{"direct":true},"footnotes":[{"field":"acquired","element":"transactionAcquiredDisposedCode","label":"F1","text":"The Reporting Person acquired the shares of common stock and warrant to purchase common stock reported on this Form 4 in connection with the Issuer's registered direct offering. 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The number of shares underlying to stock option shall vest as follows: 6,250 shares of common stock shall vest as of September 30, 2024 and the remaining 18,750 shares of common stock shall vest in equal 2,084 share amounts at the end of each month over the following continuous nine months beginning on October 31, 2024 (with 2,078 shares vesting on June 30, 2025 due to rounding adjustments). 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The $1.8887 represents a weighted average price.  The Reporting Person purchased 5,200 shares of common stock at a price of $1.89 per share and 100 shares of common stock at a price of $1.88 per share."}],"balance_after":88028,"source":{"system":"sec-edgar","filing":"0001104659-22-038736","document":"tm2210631-4_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1468929/000110465922038736/tm2210631-4_4seq1.xml","form_type":"4"}},{"id":2438144,"issuer":{"id":3803,"kind":"organization","name":"PTC THERAPEUTICS, INC.","symbol":"PTCT"},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME B","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right To Buy)","published_at":"2022-01-11T21:10:51.000Z","date":"2022-01-07","kind":"grant","acquired":true,"shares":12000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This option was granted on January 7, 2022 and vests over one year in twelve equal monthly installments, commencing on February 7, 2022."}],"balance_after":12000,"derivative":{"exercise_price":38.1,"expiration_date":"2032-01-06","underlying":"Common Stock","underlying_shares":12000},"source":{"system":"sec-edgar","filing":"0001179110-22-000387","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1070081/000117911022000387/edgar.xml","form_type":"4"}},{"id":2438143,"issuer":{"id":3803,"kind":"organization","name":"PTC THERAPEUTICS, INC.","symbol":"PTCT"},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME B","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2022-01-11T21:10:51.000Z","date":"2022-01-07","kind":"grant","acquired":true,"shares":3200,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Restricted stock units granted on January 7, 2022 that vest over one year, with five-twelfths (5/12) of the shares underlying the RSUs vesting on June 8, 2022 and the remaining seven-twelfths (7/12) of the original shares underlying the RSUs vesting on January 7, 2023. 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Pursuant to the terms of the Series C Preferred Stock and using the price calculated pursuant to the terms of the Series C Preferred Stock, the reporting person received 3,804 shares of common stock as a payment-in-kind dividend upon conversion of 50 shares of Series C Preferred Stock owned by the reporting person on the conversion date."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each share of the Series C Preferred Stock is entitled to a nine percent (9%) annual dividend on the $1,000 per share stated value. The dividends accrued and became payable in cash or, at the Issuer's option and subject to the satisfaction of certain conditions, in pay-in-kind shares. Such cumulative dividends were payable quarterly, commencing on September 30, 2013, thereafter quarterly on December 31, March 31, June 30 and September 30, and on the conversion date. The reporting person's 50 shares of Series C Preferred Stock were converted on May 21, 2019, and the Issuer elected to pay the accrued dividends in pay-in-kind shares. Pursuant to the terms of the Series C Preferred Stock and using the price calculated pursuant to the terms of the Series C Preferred Stock, the reporting person received 3,804 shares of common stock as a payment-in-kind dividend upon conversion of 50 shares of Series C Preferred Stock owned by the reporting person on the conversion date."}],"balance_after":85847,"source":{"system":"sec-edgar","filing":"0001185185-19-000802","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1433982/000118518519000802/ownership.xml","form_type":"4"}},{"id":3515111,"issuer":{"id":1816,"kind":"organization","name":"Streamex Corp.","symbol":"STEX"},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME B","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2019-05-22T17:02:19.000Z","date":"2019-05-21","kind":"exercise","acquired":true,"shares":13334,"price":3.75,"value":50002.5,"ownership":{"direct":true},"balance_after":82043,"source":{"system":"sec-edgar","filing":"0001185185-19-000802","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1433982/000118518519000802/ownership.xml","form_type":"4"}},{"id":3551658,"issuer":{"id":8067,"kind":"organization","name":"SOLIGENIX, INC.","symbol":"SNGX"},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME B","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2019-04-22T20:41:57.000Z","date":"2019-04-22","kind":"purchase","acquired":true,"shares":10000,"price":0.7274,"value":7274.0,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"This transaction was executed in multiple trades at prices ranging from $0.7198 to $0.75. The price reported above reflects the weighted average purchase price. The reporting person hereby undertakes to provide upon request to the SEC staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":16917,"source":{"system":"sec-edgar","filing":"0001213900-19-006872","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/812796/000121390019006872/ownership.xml","form_type":"4"}},{"id":3688325,"issuer":{"id":3803,"kind":"organization","name":"PTC THERAPEUTICS, INC.","symbol":"PTCT"},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME B","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to 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March 27, 2019, June 27, 2019 and September 27, 2019."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The stock option vests ratably on each of December 27, 2018, March 27, 2019, June 27, 2019 and September 27, 2019."}],"balance_after":17964,"derivative":{"exercise_price":1.67,"expiration_date":"2028-09-26","underlying":"Common Stock","underlying_shares":17964},"source":{"system":"sec-edgar","filing":"0001213900-18-013232","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/812796/000121390018013232/ownership.xml","form_type":"4"}},{"id":4105899,"issuer":{"id":3803,"kind":"organization","name":"PTC THERAPEUTICS, INC.","symbol":"PTCT"},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME 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to receive, at settlement, one share of the Company's common stock."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each restricted stock unit represents a contingent right to receive, at settlement, one share of the Company's common stock."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The restricted stock units were granted on October 11, 2017 and will vest for active service as follows: (a) 12,500 shares on January 11, 2018, (b) 12,500 shares on April 11, 2018, (c) 12,500 shares on July 11, 2018, and (d) 12,500 shares on October 11, 2018. Vested restricted stock units settle on the October 11, 2020, unless accelerated due to departure from the Company's board of directors or a change of control."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F2","text":"The restricted stock units were granted on October 11, 2017 and will vest for active service as follows: (a) 12,500 shares on January 11, 2018, (b) 12,500 shares on April 11, 2018, (c) 12,500 shares on July 11, 2018, and (d) 12,500 shares on October 11, 2018. Vested restricted stock units settle on the October 11, 2020, unless accelerated due to departure from the Company's board of directors or a change of control."}],"balance_after":50000,"derivative":{"underlying":"Common Stock","underlying_shares":50000},"source":{"system":"sec-edgar","filing":"0001415889-17-001841","document":"form4-11212017_041110.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1433982/000141588917001841/form4-11212017_041110.xml","form_type":"4"}},{"id":4208818,"issuer":{"id":109201,"kind":"organization","name":"Sorrento Therapeutics, Inc."},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME B","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Stock Options","published_at":"2017-09-15T21:45:56.000Z","date":"2017-09-14","kind":"grant","acquired":true,"shares":150000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"1/4 of the original number of shares subject to the option shall vest on September 14, 2018 and 1/48 of the original number of shares subject to the option shall vest following each one month period of service after September 14, 2018, subject to the Reporting Person's continued service to the Issuer through each such vesting date."}],"balance_after":150000,"derivative":{"exercise_price":1.8,"expiration_date":"2027-09-14","underlying":"Common Stock","underlying_shares":150000},"source":{"system":"sec-edgar","filing":"0001144204-17-048361","document":"v475327_4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/850261/000114420417048361/v475327_4.xml","form_type":"4"}},{"id":4267806,"issuer":{"id":155807,"kind":"organization","name":"Adynxx, Inc.","symbol":"ADYX"},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME B","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2017-07-03T13:46:30.000Z","date":"2017-06-30","kind":"grant","acquired":true,"shares":90000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in eleven equal monthly installments with one-eleventh (1/11) vesting on the thirtieth (30th) day of each of the next eleven (11) months (or, if there is no 30th day in a month, on the last day of that month), with the first such vesting date occurring on July 30, 2017, provided that the reporting person is providing services to the Issuer on the applicable vesting date and subject to the terms and conditions of the Alliqua BioMedical, Inc. 2014 Long-Term Incentive Plan."}],"balance_after":90000,"derivative":{"exercise_price":0.37,"expiration_date":"2027-06-30","underlying":"Common Stock","underlying_shares":90000},"source":{"system":"sec-edgar","filing":"0001144204-17-035405","document":"v470264_4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1054274/000114420417035405/v470264_4.xml","form_type":"4"}},{"id":4272752,"issuer":{"id":155807,"kind":"organization","name":"Adynxx, Inc.","symbol":"ADYX"},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME B","position":1,"cik":"0001433982","reported_name":"ZELDIS JEROME B","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2017-06-26T10:05:18.000Z","date":"2017-06-23","kind":"other","acquired":true,"shares":100000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Pursuant to a Securities Purchase Agreement (the \"Securities Purchase Agreement\"), dated February 27, 2017, with the Issuer, the Reporting Person purchased in a private placement (the \"Private Placement\") 400,000 shares of Common Stock at a purchase price of $0.50 per share (the \"Per Share Purchase Price\"). The Securities Purchase Agreement contains a \"most-favored nation\" provision that provides that if the Issuer, during 120 days from February 27, 2017, issues or sells any Common Stock or Common Stock equivalents reasonably believed to be more favorable in terms or conditions than the Private Placement, the Issuer must amend the terms of the Securities Purchase Agreement to give the Private Placement investors, including the Reporting Person, the benefit of such more favorable terms or conditions."},{"field":"kind","element":"transactionCoding","label":"F2","text":"In accordance with this provision, effective as of April 11, 2017, following a public offering of Common Stock at a purchase price of $0.40 per share (the \"Public Offering Price\") on April 3, 2017, the Issuer adjusted the Per Share Purchase Price to the Public Offering Price and is required to issue additional shares of Common Stock to the Private Placement investors, including the Reporting Person, which issuance is subject to stockholder approval as may be required by the applicable rules and regulations of the NASDAQ Capital Market and certain side letter agreement, dated March 13, 2017, between the Issuer and the Reporting Person (the \"Side Letter\")."},{"field":"kind","element":"transactionCoding","label":"F3","text":"Pursuant to the Securities Purchase Agreement and subject to the Side Letter, on June 23, 2017, the Issuer obtained stockholder approval and issued 100,000 shares of Common Stock to the Reporting Person."}],"balance_after":786750,"source":{"system":"sec-edgar","filing":"0001144204-17-033926","document":"v469565_4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1054274/000114420417033926/v469565_4.xml","form_type":"4"}},{"id":4286377,"issuer":{"id":8067,"kind":"organization","name":"SOLIGENIX, INC.","symbol":"SNGX"},"owners":[{"id":70103,"kind":"person","name":"ZELDIS JEROME 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