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Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1."}],"balance_after":128506,"source":{"system":"sec-edgar","filing":"0000935836-26-000031","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/2035832/000093583626000031/ownership.xml","form_type":"4"}},{"id":941231,"issuer":{"id":4711,"kind":"organization","name":"Aktis Oncology, Inc.","symbol":"AKTS"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T01:28:36.000Z","date":"2026-01-12","kind":"exercise","planned":false,"acquired":true,"shares":202862,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The shares of Series A Redeemable Convertible Preferred Stock and Series B Redeemable Convertible Preferred Stock converted into shares of Common Stock and Class A Common Stock on a 3.8044-for-1 basis immediately prior to the closing of the initial public offering of the Issuer's Common Stock for no additional consideration. Each share was immediately exercisable and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"These securities are held by EcoR1 Capital Fund, L.P. (\"Capital Fund\"). EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to and general partner of the fund. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1."}],"balance_after":202862,"source":{"system":"sec-edgar","filing":"0000935836-26-000031","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/2035832/000093583626000031/ownership.xml","form_type":"4"}},{"id":941230,"issuer":{"id":4711,"kind":"organization","name":"Aktis Oncology, Inc.","symbol":"AKTS"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T01:28:36.000Z","date":"2026-01-12","kind":"exercise","planned":false,"acquired":true,"shares":2270879,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The shares of Series A Redeemable Convertible Preferred Stock and Series B Redeemable Convertible Preferred Stock converted into shares of Common Stock and Class A Common Stock on a 3.8044-for-1 basis immediately prior to the closing of the initial public offering of the Issuer's Common Stock for no additional consideration. Each share was immediately exercisable and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"These securities are held by EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 Capital, LLC (\"EcoR1\") may be deemed to indirectly beneficially own them as the investment adviser to and general partner of the fund. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1."}],"balance_after":2270879,"source":{"system":"sec-edgar","filing":"0000935836-26-000031","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/2035832/000093583626000031/ownership.xml","form_type":"4"}},{"id":1100138,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Pre-Funded Warrants (right to acquire)","published_at":"2025-06-27T17:50:21.000Z","date":"2025-06-26","kind":"other","planned":false,"acquired":false,"shares":5086521,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F5","text":"Qualified Fund exercised 4,818,462 of the pre-funded warrants reported in this transaction."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F6","text":"The pre-funded warrants did not have an expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":0,"derivative":{"exercise_price":0.0001,"exercise_date":"2023-12-26","underlying":"Common Stock","underlying_shares":5086521},"source":{"system":"sec-edgar","filing":"0000935836-25-000438","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000438/ownership.xml","form_type":"4"}},{"id":1100137,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-06-27T17:50:21.000Z","date":"2025-06-26","kind":"tax_withholding","planned":false,"acquired":false,"shares":41,"price":12.71,"value":521.11,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F4","text":"On June 26, 2025,the reporting persons exercised pre-funded warrants to purchase 5,086,521 shares of the Issuer's Common Stock for $0.0001 per share. The reporting persons paid the exercise price on a cashless basis, resulting in the Issuer withholding 41 of the warrant shares (including 38 warrant shares issuable to Qualified Fund) to pay the exercise price and issuing to the reporting persons the remaining 5,086,480 shares."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"After the transactions reported herein, Qualified Fund held 21,582,563 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":22970388,"source":{"system":"sec-edgar","filing":"0000935836-25-000438","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000438/ownership.xml","form_type":"4"}},{"id":1100136,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-06-27T17:50:21.000Z","date":"2025-06-26","kind":"other","planned":false,"acquired":true,"shares":5086480,"price":0.0001,"value":508.648,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund acquired 4,818,424 shares of Common Stock in connection with the exercise of the pre-funded warrants."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"After the transactions reported herein, Qualified Fund held 21,582,563 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":22970388,"source":{"system":"sec-edgar","filing":"0000935836-25-000438","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000438/ownership.xml","form_type":"4"}},{"id":1142553,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-05-19T18:35:05.000Z","date":"2025-05-19","kind":"purchase","planned":false,"acquired":true,"shares":5919,"price":11.7821,"value":69738.2499,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F4","text":"Qualified Fund purchased 5,550 of the shares purchased in this transaction."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F5","text":"After this transaction, Qualified Fund held 16,764,139 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17883908,"source":{"system":"sec-edgar","filing":"0000935836-25-000389","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000389/ownership.xml","form_type":"4"}},{"id":1142552,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-05-19T18:35:05.000Z","date":"2025-05-15","kind":"purchase","planned":false,"acquired":true,"shares":49502,"price":11.4308,"value":565847.4616,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased 46,405 of the shares purchased in this transaction."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"After this transaction, Qualified Fund held 16,758,589 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17877989,"source":{"system":"sec-edgar","filing":"0000935836-25-000389","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000389/ownership.xml","form_type":"4"}},{"id":1169069,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-04-18T15:17:11.000Z","date":"2025-04-17","kind":"purchase","planned":false,"acquired":true,"shares":54760,"price":11.5197,"value":630818.772,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F5","text":"Qualified Fund purchased 51,344 of the shares purchased in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F6","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $11.5125 to $11.5214, inclusive."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F7","text":"After this transaction, Qualified Fund held 16,712,184 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17828487,"source":{"system":"sec-edgar","filing":"0000935836-25-000292","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000292/ownership.xml","form_type":"4"}},{"id":1169068,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-04-18T15:17:11.000Z","date":"2025-04-16","kind":"purchase","planned":false,"acquired":true,"shares":73953,"price":11.1637,"value":825589.1061,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased 69,339 of the shares purchased in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $10.9823 to $11.2339 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each seperate price within the ranges set forth in this footnote and footnote 6."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"After this transaction, Qualified Fund held 16,660,840 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17773727,"source":{"system":"sec-edgar","filing":"0000935836-25-000292","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000292/ownership.xml","form_type":"4"}},{"id":1176576,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-04-07T18:34:11.000Z","date":"2025-04-04","kind":"purchase","planned":false,"acquired":true,"shares":196438,"price":11.1679,"value":2193799.9402,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F5","text":"Qualified Fund purchased 184,181 of the shares purchased in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F6","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $10.9804 to $11.2921, inclusive."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F7","text":"After this transaction, Qualified Fund held 16,591,501 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17699774,"source":{"system":"sec-edgar","filing":"0000935836-25-000266","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000266/ownership.xml","form_type":"4"}},{"id":1176575,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-04-07T18:34:11.000Z","date":"2025-04-03","kind":"purchase","planned":false,"acquired":true,"shares":120770,"price":11.8421,"value":1430170.417,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased 113,233 of the shares purchased in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $11.8101 to $11.9123 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each seperate price within the ranges set forth in this footnote and footnote 6."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"After this transaction, Qualified Fund held 16,407,320 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17503336,"source":{"system":"sec-edgar","filing":"0000935836-25-000266","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000266/ownership.xml","form_type":"4"}},{"id":1183241,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-04-02T19:02:09.000Z","date":"2025-04-02","kind":"purchase","planned":false,"acquired":true,"shares":74360,"price":11.848,"value":881017.28,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F6","text":"Qualified Fund purchased 69,720 of the shares purchased in this transaction."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F7","text":"After this transaction, Qualified Fund held 16,294,087 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17382566,"source":{"system":"sec-edgar","filing":"0000935836-25-000259","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000259/ownership.xml","form_type":"4"}},{"id":1183240,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-04-02T19:02:09.000Z","date":"2025-04-01","kind":"purchase","planned":false,"acquired":true,"shares":48658,"price":11.6044,"value":564646.8952,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F4","text":"Qualified Fund purchased 45,622 of the shares purchased in this transaction."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F5","text":"After this transaction, Qualified Fund held 16,224,367 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17308206,"source":{"system":"sec-edgar","filing":"0000935836-25-000259","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000259/ownership.xml","form_type":"4"}},{"id":1183239,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-04-02T19:02:09.000Z","date":"2025-03-31","kind":"purchase","planned":false,"acquired":true,"shares":4397,"price":11.7485,"value":51658.1545,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased 4,129 of the shares purchased in this transaction."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"After this transaction, Qualified Fund held 16,178,745 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17259548,"source":{"system":"sec-edgar","filing":"0000935836-25-000259","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000259/ownership.xml","form_type":"4"}},{"id":1189675,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-03-27T18:53:43.000Z","date":"2025-03-26","kind":"purchase","planned":false,"acquired":true,"shares":43848,"price":12.2436,"value":536857.3728,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F4","text":"Qualified Fund purchased 41,177 of the shares purchased in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F5","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $12.2293 to $12.3537, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in this footnote."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F6","text":"After this transaction, Qualified Fund held 16,174,616 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17255151,"source":{"system":"sec-edgar","filing":"0000935836-25-000253","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000253/ownership.xml","form_type":"4"}},{"id":1189674,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-03-27T18:53:43.000Z","date":"2025-03-25","kind":"purchase","planned":false,"acquired":true,"shares":53501,"price":12.9054,"value":690451.8054,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased 50,243 of the shares purchased in this transaction."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"After this transaction, Qualified Fund held 16,133,439 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17211303,"source":{"system":"sec-edgar","filing":"0000935836-25-000253","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000253/ownership.xml","form_type":"4"}},{"id":1193344,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-03-24T17:45:12.000Z","date":"2025-03-24","kind":"purchase","planned":false,"acquired":true,"shares":22689,"price":13.0833,"value":296846.9937,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F7","text":"Qualified Fund purchased 21,307 of the shares purchased in this transaction."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F8","text":"After this transaction, Qualified Fund held 16,083,196 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17157802,"source":{"system":"sec-edgar","filing":"0000935836-25-000245","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000245/ownership.xml","form_type":"4"}},{"id":1193343,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-03-24T17:45:12.000Z","date":"2025-03-21","kind":"purchase","planned":false,"acquired":true,"shares":31033,"price":12.7773,"value":396517.9509,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F4","text":"Qualified Fund purchased 29,143 of the shares purchased in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F5","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $12.6895 to $12.9881 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in this footnote with the ranges set forth in this footnote."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F6","text":"After this transaction, Qualified Fund held 16,061,889 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17135113,"source":{"system":"sec-edgar","filing":"0000935836-25-000245","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000245/ownership.xml","form_type":"4"}},{"id":1193342,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-03-24T17:45:12.000Z","date":"2025-03-20","kind":"purchase","planned":false,"acquired":true,"shares":73476,"price":12.9278,"value":949883.0328,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased 69,000 of the shares purchased in this transaction."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"After this transaction, Qualified Fund held 16,032,746 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17104080,"source":{"system":"sec-edgar","filing":"0000935836-25-000245","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000245/ownership.xml","form_type":"4"}},{"id":1196988,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-03-19T18:32:24.000Z","date":"2025-03-19","kind":"purchase","planned":false,"acquired":true,"shares":58306,"price":12.6442,"value":737232.7252,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F8","text":"Qualified Fund purchased 54,758 of the shares purchased in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F9","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $12.5029 to $12.7711, inclusive."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F10","text":"After this transaction, Qualified Fund held 15,963,746 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":17030604,"source":{"system":"sec-edgar","filing":"0000935836-25-000239","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000239/ownership.xml","form_type":"4"}},{"id":1196987,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-03-19T18:32:24.000Z","date":"2025-03-18","kind":"purchase","planned":false,"acquired":true,"shares":113880,"price":12.6524,"value":1440855.312,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F5","text":"Qualified Fund purchased 106,944 of the shares purchased in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F6","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $12.3214 to $12.7045, inclusive."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F7","text":"After this transaction, Qualified Fund held 15,908,988 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":16972298,"source":{"system":"sec-edgar","filing":"0000935836-25-000239","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000239/ownership.xml","form_type":"4"}},{"id":1196986,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-03-19T18:32:24.000Z","date":"2025-03-17","kind":"purchase","planned":false,"acquired":true,"shares":56277,"price":12.2335,"value":688464.6795,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased 52,849 of the shares purchased in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $12.1287 to $12.2678 inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in this footnote with the ranges set forth in this footnote."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"After this transaction, Qualified Fund held 15,802,044 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":16858418,"source":{"system":"sec-edgar","filing":"0000935836-25-000239","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000239/ownership.xml","form_type":"4"}},{"id":1207711,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-03-13T19:35:15.000Z","date":"2025-03-13","kind":"purchase","planned":false,"acquired":true,"shares":468356,"price":12.4846,"value":5847237.3176,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F8","text":"Qualified Fund purchased 439,831 of the shares purchased in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F9","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $12.26 to $12.55, inclusive."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F10","text":"After this transaction, Qualified Fund held 15,749,195 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":16802141,"source":{"system":"sec-edgar","filing":"0000935836-25-000225","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000225/ownership.xml","form_type":"4"}},{"id":1207710,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-03-13T19:35:15.000Z","date":"2025-03-12","kind":"purchase","planned":false,"acquired":true,"shares":292934,"price":12.2479,"value":3587826.3386,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F5","text":"Qualified Fund purchased 275,095 of the shares purchased in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F6","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $12.0008 to $12.3728, inclusive."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F7","text":"After this transaction, Qualified Fund held 15,309,364 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":16333785,"source":{"system":"sec-edgar","filing":"0000935836-25-000225","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000225/ownership.xml","form_type":"4"}},{"id":1207709,"issuer":{"id":4458,"kind":"organization","name":"Zymeworks Inc.","symbol":"ZYME"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-03-13T19:35:15.000Z","date":"2025-03-11","kind":"purchase","planned":false,"acquired":true,"shares":320690,"price":11.4935,"value":3685850.515,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased 301,160 of the shares purchased in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $11.115 to $11.70, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in this footnote with the ranges set forth in this footnote and footnote 6 and 9."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"After this transaction, Qualified Fund held 15,034,269 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the general partner and investment adviser of private funds, including Qualified Fund (the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of the securities except to the extent of their respective pecuniary interests therein."}],"balance_after":16040851,"source":{"system":"sec-edgar","filing":"0000935836-25-000225","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000225/ownership.xml","form_type":"4"}},{"id":1318563,"issuer":{"id":4640,"kind":"organization","name":"ANAPTYSBIO, INC","symbol":"ANAB"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-01-02T18:17:02.000Z","date":"2025-01-02","kind":"purchase","planned":false,"acquired":true,"shares":6646,"price":12.9506,"value":86069.6876,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F7","text":"Qualified Fund purchased all of the securities in this transaction."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F8","text":"After this transaction, Qualified Fund held 7,401,972 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified L.P. (\"Qualified Fund\"). EcoR1 is the investment adviser and general partner of private funds, including Qualified Fund (collectively, the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1 and a director of the Issuer. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of such securities except to the extent of their pecuniary interests therein."}],"balance_after":7880094,"source":{"system":"sec-edgar","filing":"0000935836-25-000008","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000008/ownership.xml","form_type":"4"}},{"id":1318562,"issuer":{"id":4640,"kind":"organization","name":"ANAPTYSBIO, INC","symbol":"ANAB"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-01-02T18:17:02.000Z","date":"2024-12-31","kind":"purchase","planned":false,"acquired":true,"shares":13268,"price":12.9268,"value":171512.7824,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F5","text":"Qualified Fund purchased all of the securities in this transaction."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F6","text":"After this transaction, Qualified Fund held 7,395,326 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified L.P. (\"Qualified Fund\"). EcoR1 is the investment adviser and general partner of private funds, including Qualified Fund (collectively, the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1 and a director of the Issuer. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of such securities except to the extent of their pecuniary interests therein."}],"balance_after":7873448,"source":{"system":"sec-edgar","filing":"0000935836-25-000008","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000008/ownership.xml","form_type":"4"}},{"id":1318561,"issuer":{"id":4640,"kind":"organization","name":"ANAPTYSBIO, INC","symbol":"ANAB"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-01-02T18:17:02.000Z","date":"2024-12-30","kind":"purchase","planned":false,"acquired":true,"shares":65184,"price":12.9182,"value":842059.9488,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased all of the securities in this transaction."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $12.71 to $12.9552, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in footnote 3."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"After this transaction, Qualified Fund held 7,382,058 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting persons are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified L.P. (\"Qualified Fund\"). EcoR1 is the investment adviser and general partner of private funds, including Qualified Fund (collectively, the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1 and a director of the Issuer. EcoR1 is filing this Form 4 for itself and Qualified Fund. The filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to indirectly beneficially own them as the investment adviser to the Funds. Mr. Nodelman may be deemed to indirectly beneficially own them as the control person of EcoR1. The filers disclaim beneficial ownership of such securities except to the extent of their pecuniary interests therein."}],"balance_after":7860180,"source":{"system":"sec-edgar","filing":"0000935836-25-000008","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000093583625000008/ownership.xml","form_type":"4"}},{"id":1774697,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Class A Common Stock","published_at":"2023-09-22T15:44:37.000Z","date":"2023-09-21","kind":"purchase","planned":false,"acquired":true,"shares":53000,"price":1.3611,"value":72138.3,"ownership":{"direct":false,"nature":"See Notes"},"footnotes":[{"field":"date","element":"transactionDate","label":"F5","text":"Original Form 4 inadvertently identified the date of this transaction as 2/21/2023.  As reported in this amendment, the date of this transaction was 9/21/2023."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"EcoR1 Capital, LLC (\"EcoR1\") is the investment adviser to EcoR1 Capital Fund, L.P. (\"Capital Fund\"), EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds. Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The reporting persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Qualified Fund is the record holder of these securities."}],"balance_after":12674775,"source":{"system":"sec-edgar","filing":"0000935836-23-000621","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000093583623000621/ownership.xml","form_type":"4/A","original_submission_date":"2023-09-21"}},{"id":1774696,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Class A Common Stock","published_at":"2023-09-22T15:44:37.000Z","date":"2023-09-20","kind":"purchase","planned":false,"acquired":true,"shares":117100,"price":1.362,"value":159490.2,"ownership":{"direct":false,"nature":"See Notes"},"footnotes":[{"field":"date","element":"transactionDate","label":"F4","text":"The Original Form 4 inadvertently identified the date of this transaction as 2/20/2023.  As reported in this amendment, the date of this transaction was 9/20/2023."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"EcoR1 Capital, LLC (\"EcoR1\") is the investment adviser to EcoR1 Capital Fund, L.P. (\"Capital Fund\"), EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds. Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The reporting persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Qualified Fund is the record holder of these securities."}],"balance_after":12621775,"source":{"system":"sec-edgar","filing":"0000935836-23-000621","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000093583623000621/ownership.xml","form_type":"4/A","original_submission_date":"2023-09-21"}},{"id":1774695,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Class A Common Stock","published_at":"2023-09-22T15:44:37.000Z","date":"2023-09-19","kind":"purchase","planned":false,"acquired":true,"shares":5143000,"price":1.2562,"value":6460636.6,"ownership":{"direct":false,"nature":"See Notes"},"footnotes":[{"field":"date","element":"transactionDate","label":"F3","text":"On 9/21/2023, the reporting persons filed a Form 4 (the \"Original Form 4\") that inadvertently identified the date of this transaction as 2/19/2023.  As reported in this amendment, the date of this transaction was 9/19/2023. The Original Form 4 also inadvertently identified the date of the earliest transaction reported in the Original Form 4 as 2/19/2023.  As reported in this amendment, the date of the earliest transaction was 9/19/2023."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"EcoR1 Capital, LLC (\"EcoR1\") is the investment adviser to EcoR1 Capital Fund, L.P. (\"Capital Fund\"), EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds. Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The reporting persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Qualified Fund is the record holder of these securities."}],"balance_after":12504675,"source":{"system":"sec-edgar","filing":"0000935836-23-000621","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000093583623000621/ownership.xml","form_type":"4/A","original_submission_date":"2023-09-21"}},{"id":1775513,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Class A Common Stock","published_at":"2023-09-21T20:08:36.000Z","date":"2023-02-21","kind":"purchase","planned":false,"acquired":true,"shares":53000,"price":1.3611,"value":72138.3,"ownership":{"direct":false,"nature":"See Notes"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"EcoR1 Capital, LLC (\"EcoR1\") is the investment adviser to EcoR1 Capital Fund, L.P. (\"Capital Fund\"), EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds. Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The reporting persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Qualified Fund is the record holder of these securities."}],"balance_after":12674775,"source":{"system":"sec-edgar","filing":"0000935836-23-000619","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000093583623000619/ownership.xml","form_type":"4"}},{"id":1775512,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Class A Common Stock","published_at":"2023-09-21T20:08:36.000Z","date":"2023-02-20","kind":"purchase","planned":false,"acquired":true,"shares":117100,"price":1.362,"value":159490.2,"ownership":{"direct":false,"nature":"See Notes"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"EcoR1 Capital, LLC (\"EcoR1\") is the investment adviser to EcoR1 Capital Fund, L.P. (\"Capital Fund\"), EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds. Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The reporting persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Qualified Fund is the record holder of these securities."}],"balance_after":12621775,"source":{"system":"sec-edgar","filing":"0000935836-23-000619","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000093583623000619/ownership.xml","form_type":"4"}},{"id":1775511,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Class A Common Stock","published_at":"2023-09-21T20:08:36.000Z","date":"2023-02-19","kind":"purchase","planned":false,"acquired":true,"shares":5143000,"price":1.2562,"value":6460636.6,"ownership":{"direct":false,"nature":"See Notes"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"EcoR1 Capital, LLC (\"EcoR1\") is the investment adviser to EcoR1 Capital Fund, L.P. (\"Capital Fund\"), EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds. Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The reporting persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Qualified Fund is the record holder of these securities."}],"balance_after":12504675,"source":{"system":"sec-edgar","filing":"0000935836-23-000619","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000093583623000619/ownership.xml","form_type":"4"}},{"id":1908441,"issuer":{"id":114006,"kind":"organization","name":"Panacea Acquisition Corp. II","symbol":"PANA"},"owners":[{"id":114007,"kind":"person","name":"EcoR1 Panacea Holdings II, LLC","position":1,"cik":"0001842055","reported_name":"EcoR1 Panacea Holdings II, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":2,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":3,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":4,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":5,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":7,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A ordinary shares","published_at":"2023-05-02T17:15:46.000Z","date":"2023-04-28","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":545000,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"On April 10, 2023, Panacea Acquisition Corp. II (the \"Company\") announced that it did not consummate an initial business combination by April 9, 2023, the deadline under its Amended and Restated Memorandum and Articles of Association. In connection with the winding up of the Company, the Class A ordinary shares, par value $0.0001 per share, held by the Reporting Persons were surrendered for no consideration on April 28, 2023."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On April 10, 2023, Panacea Acquisition Corp. II (the \"Company\") announced that it did not consummate an initial business combination by April 9, 2023, the deadline under its Amended and Restated Memorandum and Articles of Association. In connection with the winding up of the Company, the Class A ordinary shares, par value $0.0001 per share, held by the Reporting Persons were surrendered for no consideration on April 28, 2023."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The reporting owner, EcoR1 Panacea Holdings II, LLC (the \"Sponsor\"), in whose name the securities reported herein were held, is managed by its managing members, EcoR1 Capital Fund, L.P., EcoR1 Capital Fund Qualified, L.P. and EcoR1 Venture Opportunity Fund, L.P. The general partner of EcoR1 Capital Fund, L.P. and EcoR1 Capital Fund Qualified, L.P. is EcoR1 Capital, LLC and the general partner of EcoR1 Venture Opportunity Fund, L.P. is Biotech Opportunity GP, LLC (together with EcoR1 Capital, LLC, the \"General Partners\"). Oleg Nodelman is the manager of each of the General Partners. Each of the Reporting Persons may have been deemed to be a beneficial owner of the shares held by the Sponsor but each (other than the Sponsor) disclaims beneficial ownership of any such shares except to the extent of its respective pecuniary interest therein."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001209191-23-026595","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000120919123026595/doc4.xml","form_type":"4"}},{"id":2277618,"issuer":{"id":4640,"kind":"organization","name":"ANAPTYSBIO, INC","symbol":"ANAB"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2022-05-09T06:04:35.000Z","date":"2022-05-05","kind":"sale","acquired":false,"shares":668237,"price":21.63,"value":14453966.31,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"EcoR1 Capital Fund, L.P. (\"Capital Fund\") and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") are private investment funds managed by EcoR1 Capital, LLC (\"EcoR1\") on a parri passu basis. These securities were transferred from Capital Fund to Qualified Fund as part of a periodic rebalancing of the portfolios of the funds."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The filing persons (the \"Filers\") are EcoR1, Oleg Nodelman and Qualified Fund. EcoR1 is the investment adviser and general partner of private funds, including Qualified Fund and Capital Fund (collectively, the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1 and a director of the Issuer. EcoR1 is filing this Form 4 for itself and Qualified Fund. The Filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to beneficially own the securities indirectly as the investment adviser to the Funds, and Mr. Nodelman may be deemed to beneficially own them indirectly as the control person of EcoR1. The Filers disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."}],"balance_after":7521024,"source":{"system":"sec-edgar","filing":"0001567619-22-009732","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000156761922009732/doc1.xml","form_type":"4"}},{"id":2277617,"issuer":{"id":4640,"kind":"organization","name":"ANAPTYSBIO, INC","symbol":"ANAB"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2022-05-09T06:04:35.000Z","date":"2022-05-05","kind":"purchase","acquired":true,"shares":668237,"price":21.63,"value":14453966.31,"ownership":{"direct":false,"nature":"See Notes"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"EcoR1 Capital Fund, L.P. (\"Capital Fund\") and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") are private investment funds managed by EcoR1 Capital, LLC (\"EcoR1\") on a parri passu basis. These securities were transferred from Capital Fund to Qualified Fund as part of a periodic rebalancing of the portfolios of the funds."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The filing persons (the \"Filers\") are EcoR1, Oleg Nodelman and Qualified Fund. EcoR1 is the investment adviser and general partner of private funds, including Qualified Fund and Capital Fund (collectively, the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1 and a director of the Issuer. EcoR1 is filing this Form 4 for itself and Qualified Fund. The Filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended. The Funds hold these securities directly for the benefit of their investors. EcoR1 may be deemed to beneficially own the securities indirectly as the investment adviser to the Funds, and Mr. Nodelman may be deemed to beneficially own them indirectly as the control person of EcoR1. The Filers disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"After this transaction, Qualified Fund held 7,042,903 shares of the Issuer's Common Stock."}],"balance_after":7521024,"source":{"system":"sec-edgar","filing":"0001567619-22-009732","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000156761922009732/doc1.xml","form_type":"4"}},{"id":2492213,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}}],"security":"Class A Common Stock","published_at":"2021-11-30T18:07:58.000Z","date":"2021-11-24","kind":"purchase","acquired":true,"shares":21758,"price":7.6859,"value":167229.8122,"ownership":{"direct":false,"nature":"See Notes 2 and 4"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"EcoR1 is the investment adviser to Capital Fund, Qualified Fund and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds.  Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Reporting Persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Capital Fund is the record holder of these securities."}],"balance_after":1169241,"source":{"system":"sec-edgar","filing":"0001567619-21-021329","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000156761921021329/doc1.xml","form_type":"4"}},{"id":2492212,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}}],"security":"Class A Common Stock","published_at":"2021-11-30T18:07:58.000Z","date":"2021-11-24","kind":"purchase","acquired":true,"shares":163268,"price":7.6859,"value":1254861.5212,"ownership":{"direct":false,"nature":"See Notes 2 and 3"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"EcoR1 is the investment adviser to Capital Fund, Qualified Fund and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds.  Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Reporting Persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Qualified Fund is the record holder of these securities."}],"balance_after":7361675,"source":{"system":"sec-edgar","filing":"0001567619-21-021329","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000156761921021329/doc1.xml","form_type":"4"}},{"id":2492211,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}}],"security":"Class A Common Stock","published_at":"2021-11-30T18:07:58.000Z","date":"2021-07-31","kind":"sale","acquired":false,"shares":56598,"price":8.64,"value":489006.72,"ownership":{"direct":false,"nature":"See Notes 2 and 4"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"EcoR1 Capital Fund, L.P. (\"Capital Fund\") and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") are private investment funds managed by EcoR1 Capital, LLC (\"EcoR1\") on a parri passu basis.  These securities were transferred from Capital Fund to Qualified Fund as part of a periodic rebalancing of the portfolios of the funds."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"EcoR1 is the investment adviser to Capital Fund, Qualified Fund and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds.  Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Reporting Persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Capital Fund is the record holder of these securities."}],"balance_after":1147483,"source":{"system":"sec-edgar","filing":"0001567619-21-021329","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000156761921021329/doc1.xml","form_type":"4"}},{"id":2492210,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}}],"security":"Class A Common Stock","published_at":"2021-11-30T18:07:58.000Z","date":"2021-07-31","kind":"purchase","acquired":true,"shares":56598,"price":8.64,"value":489006.72,"ownership":{"direct":false,"nature":"See Notes 2 and 3"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"EcoR1 Capital Fund, L.P. (\"Capital Fund\") and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") are private investment funds managed by EcoR1 Capital, LLC (\"EcoR1\") on a parri passu basis.  These securities were transferred from Capital Fund to Qualified Fund as part of a periodic rebalancing of the portfolios of the funds."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"EcoR1 is the investment adviser to Capital Fund, Qualified Fund and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds.  Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Reporting Persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Qualified Fund is the record holder of these securities."}],"balance_after":7198407,"source":{"system":"sec-edgar","filing":"0001567619-21-021329","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000156761921021329/doc1.xml","form_type":"4"}},{"id":2492209,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}}],"security":"Class A Common Stock","published_at":"2021-11-30T18:07:58.000Z","date":"2021-03-31","kind":"sale","acquired":true,"shares":151544,"price":10.45,"value":1583634.8,"ownership":{"direct":false,"nature":"See Notes 2 and 4"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"EcoR1 Capital Fund, L.P. (\"Capital Fund\") and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") are private investment funds managed by EcoR1 Capital, LLC (\"EcoR1\") on a parri passu basis.  These securities were transferred from Capital Fund to Qualified Fund as part of a periodic rebalancing of the portfolios of the funds."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"EcoR1 is the investment adviser to Capital Fund, Qualified Fund and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds.  Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Reporting Persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Capital Fund is the record holder of these securities."}],"balance_after":1145600,"source":{"system":"sec-edgar","filing":"0001567619-21-021329","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000156761921021329/doc1.xml","form_type":"4"}},{"id":2492208,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":6,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"Affiliate of Director"}}],"security":"Class A Common Stock","published_at":"2021-11-30T18:07:58.000Z","date":"2021-03-31","kind":"purchase","acquired":true,"shares":151544,"price":10.45,"value":1583634.8,"ownership":{"direct":false,"nature":"See Notes 2 and 3"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"EcoR1 Capital Fund, L.P. 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The Reporting Persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Qualified Fund is the record holder of these securities."}],"balance_after":6735790,"source":{"system":"sec-edgar","filing":"0001567619-21-021329","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000156761921021329/doc1.xml","form_type":"4"}},{"id":2529116,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2021-11-03T01:37:27.000Z","date":"2021-10-29","kind":"grant","acquired":true,"shares":45229,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"100% of the shares subject to the option shall vest on the earlier of: (i) the one-year anniversary of the grant date (October 29, 2022); or (ii) the next shareholder annual meeting, subject to the Reporting Person's continuous service through such applicable vesting date."}],"balance_after":45229,"derivative":{"exercise_price":9.17,"expiration_date":"2031-10-28","underlying":"Class A Common Stock","underlying_shares":45229},"source":{"system":"sec-edgar","filing":"0001209191-21-062590","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1811063/000120919121062590/doc4.xml","form_type":"4"}},{"id":2729959,"issuer":{"id":4640,"kind":"organization","name":"ANAPTYSBIO, INC","symbol":"ANAB"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-05-04T16:51:31.000Z","date":"2021-05-04","kind":"purchase","acquired":true,"shares":165000,"price":23.247,"value":3835755.0,"ownership":{"direct":false,"nature":"See Note 1"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F4","text":"Qualified Fund purchased all of the securities in this transaction.  After the transaction, Qualified Fund held 6,374,066 shares of the Issuer's Common Stock."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"Qualified Fund purchased all of the securities in this transaction.  After the transaction, Qualified Fund held 6,374,066 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The filing persons (the \"Filers\") are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the investment adviser and general partner of private funds, including Qualified Fund (collectively, the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1 and a director of the Issuer. EcoR1 is filing this Form 4 for itself and Qualified Fund. The Filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended. The Funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the Funds, and Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Filers disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."}],"balance_after":7520424,"source":{"system":"sec-edgar","filing":"0001567619-21-008992","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000156761921008992/doc1.xml","form_type":"4"}},{"id":2729958,"issuer":{"id":4640,"kind":"organization","name":"ANAPTYSBIO, INC","symbol":"ANAB"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-05-04T16:51:31.000Z","date":"2021-05-03","kind":"purchase","acquired":true,"shares":20800,"price":23.3112,"value":484872.96,"ownership":{"direct":false,"nature":"See Note 1"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F3","text":"Qualified Fund purchased all of the securities in this transaction.  After the transaction, Qualified Fund held 6,209,066 shares of the Issuer's Common Stock."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"Qualified Fund purchased all of the securities in this transaction.  After the transaction, Qualified Fund held 6,209,066 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The filing persons (the \"Filers\") are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the investment adviser and general partner of private funds, including Qualified Fund (collectively, the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1 and a director of the Issuer. EcoR1 is filing this Form 4 for itself and Qualified Fund. The Filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended. The Funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the Funds, and Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Filers disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."}],"balance_after":7355424,"source":{"system":"sec-edgar","filing":"0001567619-21-008992","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000156761921008992/doc1.xml","form_type":"4"}},{"id":2729957,"issuer":{"id":4640,"kind":"organization","name":"ANAPTYSBIO, INC","symbol":"ANAB"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-05-04T16:51:31.000Z","date":"2021-04-30","kind":"purchase","acquired":true,"shares":35700,"price":23.1601,"value":826815.57,"ownership":{"direct":false,"nature":"See Note 1"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased all of the securities in this transaction.  After the transaction, Qualified Fund held 6,188,266 shares of the Issuer's Common Stock."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Qualified Fund purchased all of the securities in this transaction.  After the transaction, Qualified Fund held 6,188,266 shares of the Issuer's Common Stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The filing persons (the \"Filers\") are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the investment adviser and general partner of private funds, including Qualified Fund (collectively, the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1 and a director of the Issuer. EcoR1 is filing this Form 4 for itself and Qualified Fund. The Filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended. The Funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the Funds, and Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Filers disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."}],"balance_after":7334624,"source":{"system":"sec-edgar","filing":"0001567619-21-008992","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000156761921008992/doc1.xml","form_type":"4"}},{"id":2738410,"issuer":{"id":4640,"kind":"organization","name":"ANAPTYSBIO, INC","symbol":"ANAB"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-04-27T18:23:07.000Z","date":"2021-04-27","kind":"purchase","acquired":true,"shares":33800,"price":23.8192,"value":805088.96,"ownership":{"direct":false,"nature":"See Note 1"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased all of the securities described in this transaction."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The filing persons (the \"Filers\") are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the investment adviser and general partner of private funds, including Qualified Fund (collectively, the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1 and a director of the Issuer. EcoR1 is filing this Form 4 for itself, Mr. Nodelman and Qualified Fund. The Filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended. The Funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the Funds, and Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Filers disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."}],"balance_after":7298924,"source":{"system":"sec-edgar","filing":"0001567619-21-008650","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000156761921008650/doc1.xml","form_type":"4"}},{"id":2738409,"issuer":{"id":4640,"kind":"organization","name":"ANAPTYSBIO, INC","symbol":"ANAB"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-04-27T18:23:07.000Z","date":"2021-04-26","kind":"purchase","acquired":true,"shares":13900,"price":23.8028,"value":330858.92,"ownership":{"direct":false,"nature":"See Note 1"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased all of the securities described in this transaction."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The filing persons (the \"Filers\") are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the investment adviser and general partner of private funds, including Qualified Fund (collectively, the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1 and a director of the Issuer. EcoR1 is filing this Form 4 for itself, Mr. Nodelman and Qualified Fund. The Filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended. The Funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the Funds, and Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Filers disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."}],"balance_after":7265124,"source":{"system":"sec-edgar","filing":"0001567619-21-008650","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000156761921008650/doc1.xml","form_type":"4"}},{"id":2738408,"issuer":{"id":4640,"kind":"organization","name":"ANAPTYSBIO, INC","symbol":"ANAB"},"owners":[{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":1,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-04-27T18:23:07.000Z","date":"2021-04-23","kind":"purchase","acquired":true,"shares":99600,"price":23.537,"value":2344285.2,"ownership":{"direct":false,"nature":"See Note 1"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"Qualified Fund purchased all of the securities described in this transaction."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The filing persons (the \"Filers\") are EcoR1 Capital, LLC (\"EcoR1\"), Oleg Nodelman and EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\"). EcoR1 is the investment adviser and general partner of private funds, including Qualified Fund (collectively, the \"Funds\"). Mr. Nodelman is the manager and controlling owner of EcoR1 and a director of the Issuer. EcoR1 is filing this Form 4 for itself, Mr. Nodelman and Qualified Fund. The Filers are filing this Form 4 jointly, but not as a group, and each expressly disclaims membership in a group within the meaning of Rule 13d-5(b) under the Securities Exchange Act of 1934, as amended. The Funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the Funds, and Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Filers disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."}],"balance_after":7251224,"source":{"system":"sec-edgar","filing":"0001567619-21-008650","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1454385/000156761921008650/doc1.xml","form_type":"4"}},{"id":2750519,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140308,"kind":"organization","name":"EcoR1 Panacea Holdings, LLC","position":6,"cik":"0001816134","reported_name":"EcoR1 Panacea Holdings, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":7,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A Common Stock","published_at":"2021-04-13T17:55:30.000Z","date":"2021-04-13","kind":"purchase","acquired":true,"shares":3966,"price":10.271,"value":40734.786,"ownership":{"direct":false,"nature":"See Notes 1 and 3"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"EcoR1 Capital, LLC (\"EcoR1\") is the investment adviser to EcoR1 Capital Fund, L.P. (\"Capital Fund\"), EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds.  Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Reporting Persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Capital Fund is the record holder of these securities."}],"balance_after":1355625,"source":{"system":"sec-edgar","filing":"0001567619-21-007976","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000156761921007976/doc1.xml","form_type":"4"}},{"id":2750518,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140308,"kind":"organization","name":"EcoR1 Panacea Holdings, LLC","position":6,"cik":"0001816134","reported_name":"EcoR1 Panacea Holdings, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":7,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A Common Stock","published_at":"2021-04-13T17:55:30.000Z","date":"2021-04-13","kind":"purchase","acquired":true,"shares":27534,"price":10.271,"value":282801.714,"ownership":{"direct":false,"nature":"See Notes 1 and 2"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"EcoR1 Capital, LLC (\"EcoR1\") is the investment adviser to EcoR1 Capital Fund, L.P. (\"Capital Fund\"), EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds.  Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Reporting Persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Qualified Fund is the record holder of these securities."}],"balance_after":6990265,"source":{"system":"sec-edgar","filing":"0001567619-21-007976","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000156761921007976/doc1.xml","form_type":"4"}},{"id":2750517,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140308,"kind":"organization","name":"EcoR1 Panacea Holdings, LLC","position":6,"cik":"0001816134","reported_name":"EcoR1 Panacea Holdings, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":7,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A Common Stock","published_at":"2021-04-13T17:55:30.000Z","date":"2021-04-12","kind":"purchase","acquired":true,"shares":16745,"price":9.4878,"value":158873.211,"ownership":{"direct":false,"nature":"See Notes 1 and 3"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"EcoR1 Capital, LLC (\"EcoR1\") is the investment adviser to EcoR1 Capital Fund, L.P. (\"Capital Fund\"), EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds.  Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Reporting Persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Capital Fund is the record holder of these securities."}],"balance_after":1351659,"source":{"system":"sec-edgar","filing":"0001567619-21-007976","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000156761921007976/doc1.xml","form_type":"4"}},{"id":2750516,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140308,"kind":"organization","name":"EcoR1 Panacea Holdings, LLC","position":6,"cik":"0001816134","reported_name":"EcoR1 Panacea Holdings, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":7,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A Common Stock","published_at":"2021-04-13T17:55:30.000Z","date":"2021-04-12","kind":"purchase","acquired":true,"shares":116255,"price":9.4878,"value":1103004.189,"ownership":{"direct":false,"nature":"See Notes 1 and 2"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"EcoR1 Capital, LLC (\"EcoR1\") is the investment adviser to EcoR1 Capital Fund, L.P. (\"Capital Fund\"), EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds.  Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Reporting Persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Qualified Fund is the record holder of these securities."}],"balance_after":6962731,"source":{"system":"sec-edgar","filing":"0001567619-21-007976","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000156761921007976/doc1.xml","form_type":"4"}},{"id":2750515,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140308,"kind":"organization","name":"EcoR1 Panacea Holdings, LLC","position":6,"cik":"0001816134","reported_name":"EcoR1 Panacea Holdings, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":7,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A Common Stock","published_at":"2021-04-13T17:55:30.000Z","date":"2021-04-09","kind":"purchase","acquired":true,"shares":37770,"price":10.0306,"value":378855.762,"ownership":{"direct":false,"nature":"See Notes 1 and 3"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"EcoR1 Capital, LLC (\"EcoR1\") is the investment adviser to EcoR1 Capital Fund, L.P. (\"Capital Fund\"), EcoR1 Capital Fund Qualified, L.P. (\"Qualified Fund\") and EcoR1 Venture Opportunity Fund, L.P. (\"Venture Fund\"). EcoR1 is the general partner of Capital Fund and Qualified Fund, and Biotech Opportunity GP, LLC (\"Biotech\") is the general partner of Venture Fund. Mr. Nodelman is the manager and controlling owner of EcoR1 and Biotech. The funds hold these securities directly for the benefit of their investors. EcoR1 indirectly beneficially owns them as the investment adviser to the funds.  Mr. Nodelman indirectly beneficially owns them as the control person of EcoR1. The Reporting Persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Capital Fund is the record holder of these securities."}],"balance_after":1334914,"source":{"system":"sec-edgar","filing":"0001567619-21-007976","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000156761921007976/doc1.xml","form_type":"4"}},{"id":2750514,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":1,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":2,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140308,"kind":"organization","name":"EcoR1 Panacea Holdings, LLC","position":6,"cik":"0001816134","reported_name":"EcoR1 Panacea Holdings, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":7,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A Common Stock","published_at":"2021-04-13T17:55:30.000Z","date":"2021-04-09","kind":"purchase","acquired":true,"shares":262230,"price":10.0306,"value":2630324.238,"ownership":{"direct":false,"nature":"See Notes 1 and 2"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"EcoR1 Capital, LLC (\"EcoR1\") is the investment adviser to EcoR1 Capital Fund, L.P. 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Each of the Reporting Persons may be deemed a beneficial owner of shares held by EcoR1 Panacea Holdings, LLC but each (other than EcoR1 Panacea Holdings, LLC) disclaims beneficial ownership of any such shares except to the extent of its respective pecuniary interest therein."}],"balance_after":3165000,"source":{"system":"sec-edgar","filing":"0001209191-21-010503","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000120919121010503/doc4.xml","form_type":"4"}},{"id":3089135,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":140308,"kind":"organization","name":"EcoR1 Panacea Holdings, LLC","position":1,"cik":"0001816134","reported_name":"EcoR1 Panacea Holdings, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69542,"kind":"person","name":"NODELMAN OLEG","position":2,"cik":"0001454385","reported_name":"NODELMAN OLEG","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"CEO and Chairman of the Board"}},{"id":109484,"kind":"person","name":"EcoR1 Capital Fund, L.P.","position":3,"cik":"0001567938","reported_name":"EcoR1 Capital Fund, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109485,"kind":"person","name":"EcoR1 Capital Fund Qualified, L.P.","position":4,"cik":"0001598292","reported_name":"EcoR1 Capital Fund Qualified, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109486,"kind":"person","name":"EcoR1 Venture Opportunity Fund, LP","position":5,"cik":"0001778011","reported_name":"EcoR1 Venture Opportunity Fund, LP","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":48279,"kind":"organization","name":"EcoR1 Capital, LLC","position":6,"cik":"0001587114","reported_name":"EcoR1 Capital, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109487,"kind":"person","name":"Biotech Opportunity GP, LLC","position":7,"cik":"0001816370","reported_name":"Biotech Opportunity GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A common stock","published_at":"2020-07-06T17:06:28.000Z","date":"2020-07-06","kind":"purchase","acquired":true,"shares":390000,"price":10,"value":3900000.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The reported shares are included within the 390,000 private placement units of the issuer purchased by EcoR1 Panacea Holdings, LLC (the \"Sponsor\") for $10.00 per private placement unit. The private placement units were purchased in a private placement that closed simultaneously with the closing of the issuer's initial public offering, and each such unit consists of one share of Class A common stock of the issuer and one-third of one redeemable warrant of the issuer. The warrants included in the units will become exercisable, if at all, on the later of 30 days after the completion of the issuer's initial business combination and 12 months from the closing of the issuer' initial public offering."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The reporting owner, the Sponsor, in whose name the securities reported herein are held, is managed by its managing members, EcoR1 Capital Fund, L.P., EcoR1 Capital Fund Qualified, L.P. and EcoR1 Venture Opportunity Fund, L.P. The general partner of EcoR1 Capital Fund, L.P. and EcoR1 Capital Fund Qualified, L.P. is EcoR1 Capital, LLC and the general partner of EcoR1 Venture Opportunity Fund, L.P. is Biotech Opportunity GP, LLC (together with EcoR1 Capital, LLC, the \"General Partners\"). Oleg Nodelman is the manager of each of the General Partners. Each of the Reporting Persons may be deemed a beneficial owner of shares held by the Sponsor but each (other than the Sponsor) disclaims beneficial ownership of any such shares except to the extent of its respective pecuniary interest therein."}],"balance_after":390000,"source":{"system":"sec-edgar","filing":"0001213900-20-016762","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1816370/000121390020016762/ownership.xml","form_type":"4"}}]}