{"transactions":[{"id":905411,"issuer":{"id":4755,"kind":"organization","name":"Alto Neuroscience, Inc.","symbol":"ANRO"},"owners":[{"id":66520,"kind":"person","name":"Hanley Jr. Michael Conick","position":1,"cik":"0001791413","reported_name":"Hanley Jr. Michael Conick","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"CHIEF OPERATING OFFICER"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2026-02-13T22:17:31.000Z","date":"2026-02-11","kind":"grant","planned":false,"acquired":true,"shares":131000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"25% of the shares underlying the option shall vest on February 11, 2027, and one forty-eighth (1/48th) of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service through each such vesting date."}],"balance_after":131000,"derivative":{"exercise_price":16.71,"expiration_date":"2036-02-10","underlying":"Common Stock","underlying_shares":131000},"source":{"system":"sec-edgar","filing":"0001791413-26-000001","document":"wk-form4_1771021048.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1999480/000179141326000001/wk-form4_1771021048.xml","form_type":"4"}},{"id":1090763,"issuer":{"id":4755,"kind":"organization","name":"Alto Neuroscience, Inc.","symbol":"ANRO"},"owners":[{"id":66520,"kind":"person","name":"Hanley Jr. Michael Conick","position":1,"cik":"0001791413","reported_name":"Hanley Jr. Michael Conick","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"CHIEF OPERATING OFFICER"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2025-07-08T21:22:49.000Z","date":"2025-07-03","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":125000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on July 3, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices greater than $2.35 per share held by continuing employees of the Issuer as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $2.35 per share, the closing price of the Issuer's common stock on the Repricing Date. However, if an employee exercises a repriced option before the end of a retention period of one year (subject to earlier termination in certain circumstances), such employee will be required to pay the original exercise price per share of such repriced option. There is no change to the vesting schedules, expiration dates of, or number of shares underlying the repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"25% of the shares underlying the option shall vest on February 5, 2026, and one forty-eighth (1/48th) of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service through each such vesting date."}],"balance_after":0,"derivative":{"exercise_price":4.2,"expiration_date":"2035-02-04","underlying":"Common Stock","underlying_shares":125000},"source":{"system":"sec-edgar","filing":"0001999480-25-000065","document":"wk-form4_1752009762.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1999480/000199948025000065/wk-form4_1752009762.xml","form_type":"4"}},{"id":1090762,"issuer":{"id":4755,"kind":"organization","name":"Alto Neuroscience, Inc.","symbol":"ANRO"},"owners":[{"id":66520,"kind":"person","name":"Hanley Jr. Michael Conick","position":1,"cik":"0001791413","reported_name":"Hanley Jr. Michael Conick","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"CHIEF OPERATING OFFICER"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2025-07-08T21:22:49.000Z","date":"2025-07-03","kind":"grant","planned":false,"acquired":true,"shares":125000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on July 3, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices greater than $2.35 per share held by continuing employees of the Issuer as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $2.35 per share, the closing price of the Issuer's common stock on the Repricing Date. However, if an employee exercises a repriced option before the end of a retention period of one year (subject to earlier termination in certain circumstances), such employee will be required to pay the original exercise price per share of such repriced option. There is no change to the vesting schedules, expiration dates of, or number of shares underlying the repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"25% of the shares underlying the option shall vest on February 5, 2026, and one forty-eighth (1/48th) of the shares underlying the option shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service through each such vesting date."}],"balance_after":125000,"derivative":{"exercise_price":2.35,"expiration_date":"2035-02-04","underlying":"Common Stock","underlying_shares":125000},"source":{"system":"sec-edgar","filing":"0001999480-25-000065","document":"wk-form4_1752009762.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1999480/000199948025000065/wk-form4_1752009762.xml","form_type":"4"}},{"id":1090761,"issuer":{"id":4755,"kind":"organization","name":"Alto Neuroscience, Inc.","symbol":"ANRO"},"owners":[{"id":66520,"kind":"person","name":"Hanley Jr. Michael Conick","position":1,"cik":"0001791413","reported_name":"Hanley Jr. Michael Conick","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"CHIEF OPERATING OFFICER"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2025-07-08T21:22:49.000Z","date":"2025-07-03","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":188000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on July 3, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices greater than $2.35 per share held by continuing employees of the Issuer as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $2.35 per share, the closing price of the Issuer's common stock on the Repricing Date. However, if an employee exercises a repriced option before the end of a retention period of one year (subject to earlier termination in certain circumstances), such employee will be required to pay the original exercise price per share of such repriced option. There is no change to the vesting schedules, expiration dates of, or number of shares underlying the repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"25% of the shares underlying the option vested on May 20, 2025, and one forty-eighth (1/48th) of the shares underlying the option vested or shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service through each such vesting date."}],"balance_after":0,"derivative":{"exercise_price":12.4,"expiration_date":"2034-05-19","underlying":"Common Stock","underlying_shares":188000},"source":{"system":"sec-edgar","filing":"0001999480-25-000065","document":"wk-form4_1752009762.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1999480/000199948025000065/wk-form4_1752009762.xml","form_type":"4"}},{"id":1090760,"issuer":{"id":4755,"kind":"organization","name":"Alto Neuroscience, Inc.","symbol":"ANRO"},"owners":[{"id":66520,"kind":"person","name":"Hanley Jr. Michael Conick","position":1,"cik":"0001791413","reported_name":"Hanley Jr. Michael Conick","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"CHIEF OPERATING OFFICER"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2025-07-08T21:22:49.000Z","date":"2025-07-03","kind":"grant","planned":false,"acquired":true,"shares":188000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on July 3, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices greater than $2.35 per share held by continuing employees of the Issuer as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $2.35 per share, the closing price of the Issuer's common stock on the Repricing Date. However, if an employee exercises a repriced option before the end of a retention period of one year (subject to earlier termination in certain circumstances), such employee will be required to pay the original exercise price per share of such repriced option. There is no change to the vesting schedules, expiration dates of, or number of shares underlying the repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"25% of the shares underlying the option vested on May 20, 2025, and one forty-eighth (1/48th) of the shares underlying the option vested or shall vest in monthly installments thereafter, subject to the Reporting Person's continuous service through each such vesting date."}],"balance_after":188000,"derivative":{"exercise_price":2.35,"expiration_date":"2034-05-19","underlying":"Common Stock","underlying_shares":188000},"source":{"system":"sec-edgar","filing":"0001999480-25-000065","document":"wk-form4_1752009762.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1999480/000199948025000065/wk-form4_1752009762.xml","form_type":"4"}},{"id":1090759,"issuer":{"id":4755,"kind":"organization","name":"Alto Neuroscience, Inc.","symbol":"ANRO"},"owners":[{"id":66520,"kind":"person","name":"Hanley Jr. Michael Conick","position":1,"cik":"0001791413","reported_name":"Hanley Jr. Michael Conick","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"CHIEF OPERATING OFFICER"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2025-07-08T21:22:49.000Z","date":"2025-07-03","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":8000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on July 3, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices greater than $2.35 per share held by continuing employees of the Issuer as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $2.35 per share, the closing price of the Issuer's common stock on the Repricing Date. However, if an employee exercises a repriced option before the end of a retention period of one year (subject to earlier termination in certain circumstances), such employee will be required to pay the original exercise price per share of such repriced option. There is no change to the vesting schedules, expiration dates of, or number of shares underlying the repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option are fully vested and exercisable."}],"balance_after":0,"derivative":{"exercise_price":14.88,"expiration_date":"2034-02-28","underlying":"Common Stock","underlying_shares":8000},"source":{"system":"sec-edgar","filing":"0001999480-25-000065","document":"wk-form4_1752009762.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1999480/000199948025000065/wk-form4_1752009762.xml","form_type":"4"}},{"id":1090758,"issuer":{"id":4755,"kind":"organization","name":"Alto Neuroscience, Inc.","symbol":"ANRO"},"owners":[{"id":66520,"kind":"person","name":"Hanley Jr. Michael Conick","position":1,"cik":"0001791413","reported_name":"Hanley Jr. Michael Conick","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"CHIEF OPERATING OFFICER"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2025-07-08T21:22:49.000Z","date":"2025-07-03","kind":"grant","planned":false,"acquired":true,"shares":8000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on July 3, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices greater than $2.35 per share held by continuing employees of the Issuer as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $2.35 per share, the closing price of the Issuer's common stock on the Repricing Date. However, if an employee exercises a repriced option before the end of a retention period of one year (subject to earlier termination in certain circumstances), such employee will be required to pay the original exercise price per share of such repriced option. There is no change to the vesting schedules, expiration dates of, or number of shares underlying the repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option are fully vested and exercisable."}],"balance_after":8000,"derivative":{"exercise_price":2.35,"expiration_date":"2034-02-28","underlying":"Common Stock","underlying_shares":8000},"source":{"system":"sec-edgar","filing":"0001999480-25-000065","document":"wk-form4_1752009762.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1999480/000199948025000065/wk-form4_1752009762.xml","form_type":"4"}},{"id":1278929,"issuer":{"id":4755,"kind":"organization","name":"Alto Neuroscience, Inc.","symbol":"ANRO"},"owners":[{"id":66520,"kind":"person","name":"Hanley Jr. Michael Conick","position":1,"cik":"0001791413","reported_name":"Hanley Jr. Michael 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Upon the achievement of certain performance criteria as certified by the Compensation Committee of the Issuer's Board of Directors, the stock option will vest as to 80% of the award by January 1, 2023, and 1/48 of the stock option will vest and become exercisable monthly thereafter until such time as the option is 100% vested."}],"balance_after":130000,"derivative":{"exercise_price":0.68,"expiration_date":"2032-08-22","underlying":"Common Stock","underlying_shares":130000},"source":{"system":"sec-edgar","filing":"0001209191-22-047649","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1636282/000120919122047649/doc4.xml","form_type":"4"}},{"id":2235317,"issuer":{"id":2649,"kind":"organization","name":"Spyre Therapeutics, Inc.","symbol":"SYRE"},"owners":[{"id":66520,"kind":"person","name":"Hanley Jr. Michael Conick","position":1,"cik":"0001791413","reported_name":"Hanley Jr. Michael 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