{"transactions":[{"id":905256,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"3.5-Year Common Stock Warrant","published_at":"2026-02-13T16:30:09.000Z","date":"2025-04-17","kind":"other","planned":false,"acquired":false,"shares":1851852,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by NEA 16, and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"Managers\"), together, the \"Indirect Reporting Persons\"). The Managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"derivative":{"exercise_price":1.37,"exercise_date":"2021-10-18","expiration_date":"2025-04-18","underlying":"Common Stock","underlying_shares":1851852},"source":{"system":"sec-edgar","filing":"0001193125-26-051537","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000119312526051537/ownership.xml","form_type":"5"}},{"id":905255,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2026-02-13T16:30:09.000Z","date":"2025-04-17","kind":"other","planned":false,"acquired":true,"shares":1851852,"price":1.37,"value":2537037.24,"ownership":{"direct":true},"footnotes":[{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by NEA 16, and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"Managers\"), together, the \"Indirect Reporting Persons\"). The Managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":12273280,"source":{"system":"sec-edgar","filing":"0001193125-26-051537","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000119312526051537/ownership.xml","form_type":"5"}},{"id":1023369,"issuer":{"id":74308,"kind":"organization","name":"NeueHealth, Inc.","symbol":"NEUE"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Warrant (Right to Buy)","published_at":"2025-10-06T17:48:48.000Z","date":"2025-10-02","kind":"exercise","planned":false,"acquired":false,"shares":372255,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The warrants became fully exercisable on October 2, 2025."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F6","text":"The warrants became fully exercisable on October 2, 2025."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\") and are indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"NEA 16 Managers\"), together, the \"NEA 16 Indirect Reporting Persons\"). The NEA 16 Managers are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell and Paul Walker. The NEA 16 Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the NEA 16 Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"derivative":{"exercise_price":0.01,"underlying":"Common Stock","underlying_shares":372255},"source":{"system":"sec-edgar","filing":"0001193125-25-232130","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000119312525232130/ownership.xml","form_type":"4"}},{"id":1023368,"issuer":{"id":74308,"kind":"organization","name":"NeueHealth, Inc.","symbol":"NEUE"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Warrant (Right to Buy)","published_at":"2025-10-06T17:48:48.000Z","date":"2025-10-02","kind":"grant","planned":false,"acquired":true,"shares":372255,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F5","text":"Warrants issued pursuant to the Warrantholders Agreement, dated September 30, 2025 between the Issuer and the holders listed on Schedule 1 thereto, and the Credit Agreement, dated August 4, 2023, as amended by that certain Incremental Amendment No. 1, dated as of October 2, 2023, that certain Incremental Amendment No. 2, dated as of April 8, 2024, that certain Amendment No. 3, dated as of June 21, 2024, that certain Amendment No. 4, dated as of October 29, 2024, and that certain Amendment No. 5, dated as of September 30, 2025, between the Issuer and the lenders thereto."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\") and are indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"NEA 16 Managers\"), together, the \"NEA 16 Indirect Reporting Persons\"). The NEA 16 Managers are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell and Paul Walker. The NEA 16 Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the NEA 16 Indirect Reporting Persons have no pecuniary interest."}],"balance_after":372255,"derivative":{"exercise_price":0.01,"exercise_date":"2025-10-02","expiration_date":"2030-10-02","underlying":"Common Stock","underlying_shares":372255},"source":{"system":"sec-edgar","filing":"0001193125-25-232130","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000119312525232130/ownership.xml","form_type":"4"}},{"id":1023367,"issuer":{"id":74308,"kind":"organization","name":"NeueHealth, Inc.","symbol":"NEUE"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Warrant (Right to Buy)","published_at":"2025-10-06T17:48:48.000Z","date":"2025-10-02","kind":"other","planned":false,"acquired":false,"shares":189195,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"The warrants became exercisable as to 123,729 shares on April 30, 2024, 1,733 shares on June 21, 2024, 61,865 shares on October 2, 2024 and 1,868 shares on September 26, 2025."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F4","text":"The warrants became exercisable as to 123,729 shares on April 30, 2024, 1,733 shares on June 21, 2024, 61,865 shares on October 2, 2024 and 1,868 shares on September 26, 2025."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by New Enterprise Associates 16, L.P. 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The NEA 16 Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the NEA 16 Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"derivative":{"exercise_price":0.01,"underlying":"Common Stock","underlying_shares":189195},"source":{"system":"sec-edgar","filing":"0001193125-25-232130","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000119312525232130/ownership.xml","form_type":"4"}},{"id":1023366,"issuer":{"id":74308,"kind":"organization","name":"NeueHealth, Inc.","symbol":"NEUE"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-10-06T17:48:48.000Z","date":"2025-10-02","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":1159683,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"Pursuant to the Agreement and Plan of Merger, dated as of December 23, 2024, by and among the Issuer, NH Holdings 2025, Inc. (\"Parent\") and NH Holdings Acquisition 2025, Inc. (\"Merger Sub\"), on October 2, 2025, Merger Sub merged with and into the Issuer with the Issuer surviving such merger as a wholly owned subsidiary of Parent (the \"Merger\"). Pursuant to rollover agreements entered into between certain of the Reporting Persons and NH Holdings 2025 SPV, L.P. (\"Ultimate Parent\"), Parent and Merger Sub, each share of the Issuer's Common Stock beneficially owned by the Reporting Persons was contributed to Ultimate Parent in exchange for limited partnership interests in Ultimate Parent. Each such share of the Issuer's Common Stock was then cancelled and ceased to exist."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\") and are indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"NEA 16 Managers\"), together, the \"NEA 16 Indirect Reporting Persons\"). The NEA 16 Managers are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell and Paul Walker. The NEA 16 Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the NEA 16 Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001193125-25-232130","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000119312525232130/ownership.xml","form_type":"4"}},{"id":1023365,"issuer":{"id":74308,"kind":"organization","name":"NeueHealth, Inc.","symbol":"NEUE"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-10-06T17:48:48.000Z","date":"2025-10-02","kind":"tax_withholding","planned":false,"acquired":false,"shares":551,"price":6.75,"value":3719.25,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F2","text":"Represents the cashless net exercise of a warrant through the surrender of shares to the Issuer based on a fair market value of $6.75 per share, the closing market price of the Issuer's common stock on October 1, 2025."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by New Enterprise Associates 16, L.P. 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The NEA 16 Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the NEA 16 Indirect Reporting Persons have no pecuniary interest."}],"balance_after":1160234,"source":{"system":"sec-edgar","filing":"0001193125-25-232130","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000119312525232130/ownership.xml","form_type":"4"}},{"id":1023363,"issuer":{"id":74308,"kind":"organization","name":"NeueHealth, Inc.","symbol":"NEUE"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2025-10-06T17:48:48.000Z","date":"2025-10-02","kind":"sale","planned":false,"acquired":false,"shares":280,"price":6.75,"value":1890.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F2","text":"Represents the cashless net exercise of a warrant through the surrender of shares to the Issuer based on a fair market value of $6.75 per share, the closing market price of the Issuer's common stock on October 1, 2025."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by New Enterprise Associates 16, L.P. 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The NEA 16 Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the NEA 16 Indirect Reporting Persons have no pecuniary interest."}],"balance_after":788259,"source":{"system":"sec-edgar","filing":"0001193125-25-232130","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000119312525232130/ownership.xml","form_type":"4"}},{"id":1323293,"issuer":{"id":7609,"kind":"organization","name":"Marker Therapeutics, Inc."},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":61210,"kind":"person","name":"BASKETT FOREST","position":4,"cik":"0001277631","reported_name":"BASKETT FOREST","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":38171,"kind":"person","name":"Chang Carmen","position":5,"cik":"0001746342","reported_name":"Chang Carmen","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":31983,"kind":"person","name":"Behbahani Ali","position":6,"cik":"0001613867","reported_name":"Behbahani Ali","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":23293,"kind":"person","name":"Florence Anthony A. 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Jr.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":23295,"kind":"person","name":"Makhzoumi Mohamad","position":8,"cik":"0001630226","reported_name":"Makhzoumi Mohamad","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":23294,"kind":"person","name":"SANDELL SCOTT D","position":9,"cik":"0001237289","reported_name":"SANDELL SCOTT D","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":61190,"kind":"person","name":"Walker Paul Edward","position":10,"cik":"0001553150","reported_name":"Walker Paul Edward","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2024-12-23T21:40:48.000Z","date":"2024-12-23","kind":"purchase","planned":false,"acquired":true,"shares":554250,"price":3.2,"value":1773600.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer on December 23, 2024 pursuant to a Securities Purchase Agreement dated December 19, 2024."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"On January 26, 2023, the Issuer effected a 1-for-10 reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of securities reported on this Form 4 have been adjusted to reflect the Reverse Stock Split."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The securities are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi,  Scott D. Sandell, and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":1625678,"source":{"system":"sec-edgar","filing":"0000950170-24-139630","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1094038/000095017024139630/ownership.xml","form_type":"4"}},{"id":1392103,"issuer":{"id":74308,"kind":"organization","name":"NeueHealth, Inc.","symbol":"NEUE"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Warrant (Right to Buy)","published_at":"2024-10-03T18:12:50.000Z","date":"2024-10-01","kind":"purchase","planned":false,"acquired":true,"shares":61865,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Warrants issued pursuant to the Warrantholders Agreement, dated April 8, 2024, between the Issuer and the holders listed on Schedule 1 thereto, and the Credit Agreement, dated August 4, 2023, as amended by that certain Incremental Amendment No. 1, dated as of October 2, 2023, and that certain Incremental Amendment No. 2, dated as of April 8, 2024, between the Issuer and the lenders thereto."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\") and are indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"NEA 16 Managers\"), together, the \"NEA 16 Indirect Reporting Persons\"). The NEA 16 Managers are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell and Paul Walker. The NEA 16 Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the NEA 16 Indirect Reporting Persons have no pecuniary interest."}],"balance_after":185594,"derivative":{"exercise_price":0.01,"exercise_date":"2024-10-02","expiration_date":"2029-04-30","underlying":"Common Stock","underlying_shares":61865},"source":{"system":"sec-edgar","filing":"0000950170-24-112582","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000095017024112582/ownership.xml","form_type":"4"}},{"id":1543828,"issuer":{"id":74308,"kind":"organization","name":"NeueHealth, Inc.","symbol":"NEUE"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Warrant (Right to Buy)","published_at":"2024-04-10T18:41:31.000Z","date":"2024-04-08","kind":"purchase","planned":false,"acquired":true,"shares":123729,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"Warrants to be issued pursuant to the Warrantholders Agreement and the Credit Agreement, dated August 4, 2023, as amended by that certain Incremental Amendment No. 1, dated as of October 2, 2023, and that certain Incremental Amendment No. 2, dated as of April 8, 2024, between the Issuer and the lenders thereto."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Pursuant to the Warrantholders Agreement (\"Warrantholders Agreement\"), dated April 8, 2024, between the Issuer and the holders listed on Schedule 1 thereto, the warrants will be issued on the first business day following the conclusion of the 10 calendar day period after the distribution of the letter required to be mailed by the Issuer to its shareholders pursuant to Section 312.05 of the NYSE Listed Company Manual (such date, the \"Closing Date\"). The warrants will be exercisable at any time after issuance and prior to the close of business on the fifth anniversary of the Closing Date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Pursuant to the Warrantholders Agreement (\"Warrantholders Agreement\"), dated April 8, 2024, between the Issuer and the holders listed on Schedule 1 thereto, the warrants will be issued on the first business day following the conclusion of the 10 calendar day period after the distribution of the letter required to be mailed by the Issuer to its shareholders pursuant to Section 312.05 of the NYSE Listed Company Manual (such date, the \"Closing Date\"). The warrants will be exercisable at any time after issuance and prior to the close of business on the fifth anniversary of the Closing Date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The securities are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\") and are indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"NEA 16 Managers\"), together, the \"NEA 16 Indirect Reporting Persons\"). The NEA 16 Managers are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell and Paul Walker. The NEA 16 Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the NEA 16 Indirect Reporting Persons have no pecuniary interest."}],"balance_after":123729,"derivative":{"exercise_price":0.01,"underlying":"Common Stock","underlying_shares":123729},"source":{"system":"sec-edgar","filing":"0000950170-24-043468","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000095017024043468/ownership.xml","form_type":"4"}},{"id":1854427,"issuer":{"id":2416,"kind":"organization","name":"Mirum Pharmaceuticals, Inc.","symbol":"MIRM"},"owners":[{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":1,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":2,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2023-06-15T20:24:45.000Z","date":"2023-06-13","kind":"other","planned":false,"acquired":false,"shares":30000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F5","text":"NEA Partners 16 made a pro rata distribution for no consideration of an aggregate of 30,000 shares of Common Stock of the Issuer to its limited partners on June 13, 2023."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F4","text":"The securities are directly held by NEA Partners 16 and indirectly held by NEA 16 GP, the sole general partner of NEA Partners 16, and the NEA 16 Managers (NEA 16 GP and the NEA 16 Managers together, the \"NEA Partners 16 Indirect Reporting Persons\"). The NEA Partners 16 Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA Partners 16 in which the NEA Partners 16 Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001209191-23-037343","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1759425/000120919123037343/doc4.xml","form_type":"4"}},{"id":1854426,"issuer":{"id":2416,"kind":"organization","name":"Mirum Pharmaceuticals, Inc.","symbol":"MIRM"},"owners":[{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":1,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":2,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2023-06-15T20:24:45.000Z","date":"2023-06-13","kind":"other","planned":false,"acquired":true,"shares":30000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F3","text":"NEA Partners 16 received 30,000 shares of Common Stock of the Issuer in the distribution made by NEA 16 on June 13, 2023."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F4","text":"The securities are directly held by NEA Partners 16 and indirectly held by NEA 16 GP, the sole general partner of NEA Partners 16, and the NEA 16 Managers (NEA 16 GP and the NEA 16 Managers together, the \"NEA Partners 16 Indirect Reporting Persons\"). The NEA Partners 16 Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA Partners 16 in which the NEA Partners 16 Indirect Reporting Persons have no pecuniary interest."}],"balance_after":30000,"source":{"system":"sec-edgar","filing":"0001209191-23-037343","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1759425/000120919123037343/doc4.xml","form_type":"4"}},{"id":1854425,"issuer":{"id":2416,"kind":"organization","name":"Mirum Pharmaceuticals, Inc.","symbol":"MIRM"},"owners":[{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":1,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":2,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2023-06-15T20:24:45.000Z","date":"2023-06-13","kind":"other","planned":false,"acquired":false,"shares":2000000,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Note 2"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"New Enterprise Associates 16, L.P. (\"NEA 16\") made a pro rata distribution of 2,000,000 shares of Common Stock of the Issuer to its general partner and limited partners for no consideration on June 13, 2023."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are directly held by NEA 16 and are indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"NEA 16 Managers\"), together, the \"NEA 16 Indirect Reporting Persons\"). The NEA 16 Managers are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell and Paul Walker. The NEA 16 Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the NEA 16 Indirect Reporting Persons have no pecuniary interest."}],"balance_after":2186243,"source":{"system":"sec-edgar","filing":"0001209191-23-037343","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1759425/000120919123037343/doc4.xml","form_type":"4"}},{"id":2098385,"issuer":{"id":11574,"kind":"organization","name":"Akouos, Inc.","symbol":"AKUS"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2022-12-02T17:01:08.000Z","date":"2022-11-30","kind":"other","acquired":false,"shares":4294207,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Pursuant to the terms of that certain Agreement and Plan of Merger (the \"Merger Agreement\"), by and among the Issuer, Eli Lilly and Company (\"Parent\") and Kearny Acquisition Corporation (\"Merger Sub\"), dated as of October 17, 2022, these shares of common stock, par value $0.0001 per share, of the Issuer (\"Shares\") were tendered prior to the Expiration Date (as defined in the Merger Agreement) and disposed of at the Acceptance Time (as defined in the Merger Agreement) in exchange for (i) $12.50 per Share, net to the stockholder in cash, without interest and less any applicable tax withholding, plus (ii) one non-tradable contingent value right (\"CVR\") per Share, which represents the contractual right to receive contingent payments of up to $3.00 per CVR, net to the stockholder in cash, without interest and less any applicable tax withholding, [Continued on Note 2]"},{"field":"shares","element":"transactionShares","label":"F2","text":"[Continuation of Note 1] upon the achievement of certain specified milestones in accordance with the terms and subject to the conditions of a Contingent Value Rights Agreement, dated as of November 30, 2022, by and among Parent, Merger Sub, Computershare Inc. and Computershare Trust Company, N.A."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Pursuant to the terms of that certain Agreement and Plan of Merger (the \"Merger Agreement\"), by and among the Issuer, Eli Lilly and Company (\"Parent\") and Kearny Acquisition Corporation (\"Merger Sub\"), dated as of October 17, 2022, these shares of common stock, par value $0.0001 per share, of the Issuer (\"Shares\") were tendered prior to the Expiration Date (as defined in the Merger Agreement) and disposed of at the Acceptance Time (as defined in the Merger Agreement) in exchange for (i) $12.50 per Share, net to the stockholder in cash, without interest and less any applicable tax withholding, plus (ii) one non-tradable contingent value right (\"CVR\") per Share, which represents the contractual right to receive contingent payments of up to $3.00 per CVR, net to the stockholder in cash, without interest and less any applicable tax withholding, [Continued on Note 2]"},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"[Continuation of Note 1] upon the achievement of certain specified milestones in accordance with the terms and subject to the conditions of a Contingent Value Rights Agreement, dated as of November 30, 2022, by and among Parent, Merger Sub, Computershare Inc. and Computershare Trust Company, N.A."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The securities are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"Managers\") together, the \"Indirect Reporting Persons\"). The Managers are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 securities in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001209191-22-059440","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1722271/000120919122059440/doc4.xml","form_type":"4"}},{"id":2255330,"issuer":{"id":12635,"kind":"organization","name":"GENOCEA BIOSCIENCES, INC.","symbol":"GNCA"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2022-05-26T18:26:37.000Z","date":"2022-05-25","kind":"sale","acquired":false,"shares":4445093,"price":0.0816,"value":362719.5888,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $0.0675 to $0.0980, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote (3) to this Form 4."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001209191-22-032327","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919122032327/doc4.xml","form_type":"4"}},{"id":2255329,"issuer":{"id":12635,"kind":"organization","name":"GENOCEA BIOSCIENCES, INC.","symbol":"GNCA"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2022-05-26T18:26:37.000Z","date":"2022-05-24","kind":"sale","acquired":false,"shares":5931843,"price":0.0654,"value":387942.5322,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $0.060 to\n$0.0746, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and\nExchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in\nthis footnote (1) to this Form 4."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":4445093,"source":{"system":"sec-edgar","filing":"0001209191-22-032327","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919122032327/doc4.xml","form_type":"4"}},{"id":2297791,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2022-04-13T17:00:03.000Z","date":"2022-04-11","kind":"purchase","acquired":true,"shares":2631578,"price":1.9,"value":4999998.2,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer on April 11, 2022 pursuant to a Securities Purchase Agreement dated April 6, 2022."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"Managers\") together, the \"Indirect Reporting Persons\"). The Managers are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 securities in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":10421428,"source":{"system":"sec-edgar","filing":"0001209191-22-024301","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919122024301/doc4.xml","form_type":"4"}},{"id":2458641,"issuer":{"id":115177,"kind":"organization","name":"Metacrine, Inc.","symbol":"MTCR"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-12-27T16:40:21.000Z","date":"2021-12-22","kind":"sale","acquired":false,"shares":170932,"price":0.9101,"value":155565.2132,"ownership":{"direct":true},"footnotes":[{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 LLC\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 LLC (NEA Partners 16, NEA 16 LLC and the individual managers of NEA 16 LLC (collectively, the \"Managers\") together, the \"Indirect Reporting Persons\"). The Managers of NEA 16 LLC are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 securities in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":2563257,"source":{"system":"sec-edgar","filing":"0001209191-21-071265","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919121071265/doc4.xml","form_type":"4"}},{"id":2458640,"issuer":{"id":115177,"kind":"organization","name":"Metacrine, Inc.","symbol":"MTCR"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-12-27T16:40:21.000Z","date":"2021-12-22","kind":"sale","acquired":false,"shares":288768,"price":1.0018,"value":289287.7824,"ownership":{"direct":true},"footnotes":[{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 LLC\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 LLC (NEA Partners 16, NEA 16 LLC and the individual managers of NEA 16 LLC (collectively, the \"Managers\") together, the \"Indirect Reporting Persons\"). The Managers of NEA 16 LLC are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 securities in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":2734189,"source":{"system":"sec-edgar","filing":"0001209191-21-071265","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919121071265/doc4.xml","form_type":"4"}},{"id":2458639,"issuer":{"id":115177,"kind":"organization","name":"Metacrine, Inc.","symbol":"MTCR"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-12-27T16:40:21.000Z","date":"2021-12-10","kind":"sale","acquired":false,"shares":37570,"price":1.321,"value":49629.97,"ownership":{"direct":true},"footnotes":[{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 LLC\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 LLC (NEA Partners 16, NEA 16 LLC and the individual managers of NEA 16 LLC (collectively, the \"Managers\") together, the \"Indirect Reporting Persons\"). The Managers of NEA 16 LLC are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 securities in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":3022957,"source":{"system":"sec-edgar","filing":"0001209191-21-071265","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919121071265/doc4.xml","form_type":"4"}},{"id":2539388,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"7-Year Common Stock Warrant","published_at":"2021-10-19T21:09:17.000Z","date":"2021-10-18","kind":"purchase","acquired":true,"shares":1851852,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Represents securities acquired pursuant to a Securities Purchase Agreement (the \"SPA\"), dated October 15, 2021, by and between the Issuer and New Enterprise Associates 16, L.P. (\"NEA 16\"), with a closing on October 18, 2021. Pursuant to the terms of the SPA, NEA 16 purchased common units for $1.62 per common unit. Each common unit consisted of one share of the Issuer's common stock, one 3.5 year common stock warrant, and one 7-year common stock warrant."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by NEA 16, and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"Managers\"), together, the \"Indirect Reporting Persons\"). The Managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":1851852,"derivative":{"exercise_price":1.37,"exercise_date":"2021-10-18","expiration_date":"2028-10-18","underlying":"Common Stock","underlying_shares":1851852},"source":{"system":"sec-edgar","filing":"0001209191-21-061090","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919121061090/doc4.xml","form_type":"4"}},{"id":2539387,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"3.5-Year Common Stock Warrant","published_at":"2021-10-19T21:09:17.000Z","date":"2021-10-18","kind":"purchase","acquired":true,"shares":1851852,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Represents securities acquired pursuant to a Securities Purchase Agreement (the \"SPA\"), dated October 15, 2021, by and between the Issuer and New Enterprise Associates 16, L.P. (\"NEA 16\"), with a closing on October 18, 2021. Pursuant to the terms of the SPA, NEA 16 purchased common units for $1.62 per common unit. Each common unit consisted of one share of the Issuer's common stock, one 3.5 year common stock warrant, and one 7-year common stock warrant."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by NEA 16, and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"Managers\"), together, the \"Indirect Reporting Persons\"). The Managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":1851852,"derivative":{"exercise_price":1.37,"exercise_date":"2021-10-18","expiration_date":"2025-04-18","underlying":"Common Stock","underlying_shares":1851852},"source":{"system":"sec-edgar","filing":"0001209191-21-061090","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919121061090/doc4.xml","form_type":"4"}},{"id":2539386,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-10-19T21:09:17.000Z","date":"2021-10-18","kind":"purchase","acquired":true,"shares":1851852,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Represents securities acquired pursuant to a Securities Purchase Agreement (the \"SPA\"), dated October 15, 2021, by and between the Issuer and New Enterprise Associates 16, L.P. (\"NEA 16\"), with a closing on October 18, 2021. Pursuant to the terms of the SPA, NEA 16 purchased common units for $1.62 per common unit. Each common unit consisted of one share of the Issuer's common stock, one 3.5 year common stock warrant, and one 7-year common stock warrant."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by NEA 16, and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP (collectively, the \"Managers\"), together, the \"Indirect Reporting Persons\"). The Managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":7789850,"source":{"system":"sec-edgar","filing":"0001209191-21-061090","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919121061090/doc4.xml","form_type":"4"}},{"id":2779881,"issuer":{"id":7609,"kind":"organization","name":"Marker Therapeutics, Inc."},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-03-18T21:08:23.000Z","date":"2021-03-16","kind":"purchase","acquired":true,"shares":5714285,"price":1.75,"value":9999998.75,"ownership":{"direct":true},"footnotes":[{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":10714285,"source":{"system":"sec-edgar","filing":"0001209191-21-021809","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1094038/000120919121021809/doc4.xml","form_type":"4"}},{"id":2955276,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A-3 Convertible Preferred Stock","published_at":"2020-12-07T17:06:40.000Z","date":"2020-12-04","kind":"purchase","acquired":true,"shares":258707,"price":6.22,"value":1609157.54,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F3","text":"Each share of Class A-3 Convertible Preferred Stock, par value $0.001 per share (\"Class A-3 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of\nthe Issuer at a rate of 10 shares of Common Stock for each share of Class A-3 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-3 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-3 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated December 1, 2020 with a closing date of December 4, 2020."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"Each share of Class A-3 Convertible Preferred Stock, par value $0.001 per share (\"Class A-3 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of\nthe Issuer at a rate of 10 shares of Common Stock for each share of Class A-3 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-3 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-3 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F3","text":"Each share of Class A-3 Convertible Preferred Stock, par value $0.001 per share (\"Class A-3 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of\nthe Issuer at a rate of 10 shares of Common Stock for each share of Class A-3 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-3 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-3 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the\nsole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul\nWalker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in\nwhich the Indirect Reporting Persons have no pecuinary interest."}],"balance_after":258707,"derivative":{"exercise_date":"2020-12-04","underlying":"Common Stock","underlying_shares":2587070},"source":{"system":"sec-edgar","filing":"0001209191-20-061962","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120061962/doc4.xml","form_type":"4"}},{"id":2955275,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock Purchase Warrant (right to buy)","published_at":"2020-12-07T17:06:40.000Z","date":"2020-12-04","kind":"purchase","acquired":true,"shares":5239254,"price":0.125,"value":654906.75,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated December 1, 2020 with a closing date of December 4, 2020."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the\nsole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul\nWalker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in\nwhich the Indirect Reporting Persons have no pecuinary interest."}],"balance_after":5239254,"derivative":{"exercise_price":0.7464,"exercise_date":"2020-12-04","expiration_date":"2025-12-04","underlying":"Common Stock","underlying_shares":5239254},"source":{"system":"sec-edgar","filing":"0001209191-20-061962","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120061962/doc4.xml","form_type":"4"}},{"id":2955274,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-12-07T17:06:40.000Z","date":"2020-12-04","kind":"purchase","acquired":true,"shares":4398602,"price":0.622,"value":2735930.444,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated December 1, 2020 with a closing date of December 4, 2020."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the\nsole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul\nWalker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in\nwhich the Indirect Reporting Persons have no pecuinary interest."}],"balance_after":6451056,"source":{"system":"sec-edgar","filing":"0001209191-20-061962","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120061962/doc4.xml","form_type":"4"}},{"id":3025040,"issuer":{"id":115177,"kind":"organization","name":"Metacrine, Inc.","symbol":"MTCR"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series C Convertible Preferred Stock","published_at":"2020-09-22T17:40:28.000Z","date":"2020-09-18","kind":"exercise","acquired":false,"shares":332964,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Every 5.1 shares of Series B Convertible Preferred Stock and Series C Convertible Preferred Stock (the \"Preferred Stock\") automatically converted into 1 share of Common Stock upon the closing of the Issuer's initial public offering. Share numbers give effect to such conversion. The Preferred Stock has no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Every 5.1 shares of Series B Convertible Preferred Stock and Series C Convertible Preferred Stock (the \"Preferred Stock\") automatically converted into 1 share of Common Stock upon the closing of the Issuer's initial public offering. Share numbers give effect to such conversion. The Preferred Stock has no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Every 5.1 shares of Series B Convertible Preferred Stock and Series C Convertible Preferred Stock (the \"Preferred Stock\") automatically converted into 1 share of Common Stock upon the closing of the Issuer's initial public offering. Share numbers give effect to such conversion. The Preferred Stock has no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 LLC\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 LLC (NEA Partners 16, NEA 16 LLC and the individual managers of NEA 16 LLC, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 LLC are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 shares in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":332964},"source":{"system":"sec-edgar","filing":"0001209191-20-051525","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120051525/doc4.xml","form_type":"4"}},{"id":3025039,"issuer":{"id":115177,"kind":"organization","name":"Metacrine, Inc.","symbol":"MTCR"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series B Convertible Preferred Stock","published_at":"2020-09-22T17:40:28.000Z","date":"2020-09-18","kind":"exercise","acquired":false,"shares":1958333,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Every 5.1 shares of Series B Convertible Preferred Stock and Series C Convertible Preferred Stock (the \"Preferred Stock\") automatically converted into 1 share of Common Stock upon the closing of the Issuer's initial public offering. Share numbers give effect to such conversion. The Preferred Stock has no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Every 5.1 shares of Series B Convertible Preferred Stock and Series C Convertible Preferred Stock (the \"Preferred Stock\") automatically converted into 1 share of Common Stock upon the closing of the Issuer's initial public offering. Share numbers give effect to such conversion. The Preferred Stock has no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Every 5.1 shares of Series B Convertible Preferred Stock and Series C Convertible Preferred Stock (the \"Preferred Stock\") automatically converted into 1 share of Common Stock upon the closing of the Issuer's initial public offering. Share numbers give effect to such conversion. The Preferred Stock has no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 LLC\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 LLC (NEA Partners 16, NEA 16 LLC and the individual managers of NEA 16 LLC, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 LLC are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 shares in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":1958333},"source":{"system":"sec-edgar","filing":"0001209191-20-051525","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120051525/doc4.xml","form_type":"4"}},{"id":3025038,"issuer":{"id":115177,"kind":"organization","name":"Metacrine, Inc.","symbol":"MTCR"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-09-22T17:40:28.000Z","date":"2020-09-18","kind":"purchase","acquired":true,"shares":769230,"price":13,"value":9999990.0,"ownership":{"direct":true},"footnotes":[{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 LLC\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 LLC (NEA Partners 16, NEA 16 LLC and the individual managers of NEA 16 LLC, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 LLC are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 shares in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":3060527,"source":{"system":"sec-edgar","filing":"0001209191-20-051525","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120051525/doc4.xml","form_type":"4"}},{"id":3025037,"issuer":{"id":115177,"kind":"organization","name":"Metacrine, Inc.","symbol":"MTCR"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-09-22T17:40:28.000Z","date":"2020-09-18","kind":"exercise","acquired":true,"shares":332964,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Every 5.1 shares of Series B Convertible Preferred Stock and Series C Convertible Preferred Stock (the \"Preferred Stock\") automatically converted into 1 share of Common Stock upon the closing of the Issuer's initial public offering. Share numbers give effect to such conversion. The Preferred Stock has no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Every 5.1 shares of Series B Convertible Preferred Stock and Series C Convertible Preferred Stock (the \"Preferred Stock\") automatically converted into 1 share of Common Stock upon the closing of the Issuer's initial public offering. Share numbers give effect to such conversion. The Preferred Stock has no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 LLC\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 LLC (NEA Partners 16, NEA 16 LLC and the individual managers of NEA 16 LLC, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 LLC are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 shares in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":2291297,"source":{"system":"sec-edgar","filing":"0001209191-20-051525","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120051525/doc4.xml","form_type":"4"}},{"id":3025036,"issuer":{"id":115177,"kind":"organization","name":"Metacrine, Inc.","symbol":"MTCR"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-09-22T17:40:28.000Z","date":"2020-09-18","kind":"exercise","acquired":true,"shares":1958333,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Every 5.1 shares of Series B Convertible Preferred Stock and Series C Convertible Preferred Stock (the \"Preferred Stock\") automatically converted into 1 share of Common Stock upon the closing of the Issuer's initial public offering. Share numbers give effect to such conversion. The Preferred Stock has no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Every 5.1 shares of Series B Convertible Preferred Stock and Series C Convertible Preferred Stock (the \"Preferred Stock\") automatically converted into 1 share of Common Stock upon the closing of the Issuer's initial public offering. Share numbers give effect to such conversion. The Preferred Stock has no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 LLC\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 LLC (NEA Partners 16, NEA 16 LLC and the individual managers of NEA 16 LLC, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 LLC are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 shares in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":1958333,"source":{"system":"sec-edgar","filing":"0001209191-20-051525","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120051525/doc4.xml","form_type":"4"}},{"id":3074919,"issuer":{"id":12635,"kind":"organization","name":"GENOCEA BIOSCIENCES, INC.","symbol":"GNCA"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Warrant to Purchase Common Stock","published_at":"2020-07-28T17:19:55.000Z","date":"2020-07-24","kind":"purchase","acquired":true,"shares":3151260,"price":0.13,"value":409663.8,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the issuer pursuant to a Stock Purchase Agreement dated July 22, 2020, with a closing date of July 24, 2020."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":3151260,"derivative":{"exercise_price":2.25,"exercise_date":"2020-07-24","expiration_date":"2024-07-24","underlying":"Common Stock","underlying_shares":3151260},"source":{"system":"sec-edgar","filing":"0001209191-20-043862","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120043862/doc4.xml","form_type":"4"}},{"id":3074918,"issuer":{"id":12635,"kind":"organization","name":"GENOCEA BIOSCIENCES, INC.","symbol":"GNCA"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-07-28T17:19:55.000Z","date":"2020-07-24","kind":"purchase","acquired":true,"shares":3151260,"price":2.25,"value":7090335.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the issuer pursuant to a Stock Purchase Agreement dated July 22, 2020, with a closing date of July 24, 2020."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":10376936,"source":{"system":"sec-edgar","filing":"0001209191-20-043862","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120043862/doc4.xml","form_type":"4"}},{"id":3095378,"issuer":{"id":11574,"kind":"organization","name":"Akouos, Inc.","symbol":"AKUS"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series B Preferred Stock","published_at":"2020-07-01T17:45:07.000Z","date":"2020-06-30","kind":"exercise","acquired":false,"shares":1199976,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F4","text":"On June 30, 2020, the Series B Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series B Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"On June 30, 2020, the Series B Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series B Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F4","text":"On June 30, 2020, the Series B Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series B Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 shares in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":1199976},"source":{"system":"sec-edgar","filing":"0001209191-20-039849","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1722271/000120919120039849/doc4.xml","form_type":"4"}},{"id":3095377,"issuer":{"id":11574,"kind":"organization","name":"Akouos, Inc.","symbol":"AKUS"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A Preferred Stock","published_at":"2020-07-01T17:45:07.000Z","date":"2020-06-30","kind":"exercise","acquired":false,"shares":1992238,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F3","text":"On June 30, 2020, the Series A Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"On June 30, 2020, the Series A Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"On June 30, 2020, the Series A Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 shares in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":1992238},"source":{"system":"sec-edgar","filing":"0001209191-20-039849","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1722271/000120919120039849/doc4.xml","form_type":"4"}},{"id":3095376,"issuer":{"id":11574,"kind":"organization","name":"Akouos, Inc.","symbol":"AKUS"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series Seed Preferred Stock","published_at":"2020-07-01T17:45:07.000Z","date":"2020-06-30","kind":"exercise","acquired":false,"shares":513758,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"On June 30, 2020, the Series Seed Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series Seed Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"On June 30, 2020, the Series Seed Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series Seed Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"On June 30, 2020, the Series Seed Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series Seed Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 shares in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":513758},"source":{"system":"sec-edgar","filing":"0001209191-20-039849","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1722271/000120919120039849/doc4.xml","form_type":"4"}},{"id":3095375,"issuer":{"id":11574,"kind":"organization","name":"Akouos, Inc.","symbol":"AKUS"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-07-01T17:45:07.000Z","date":"2020-06-30","kind":"purchase","acquired":true,"shares":588235,"price":17,"value":9999995.0,"ownership":{"direct":true},"footnotes":[{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 shares in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":4294207,"source":{"system":"sec-edgar","filing":"0001209191-20-039849","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1722271/000120919120039849/doc4.xml","form_type":"4"}},{"id":3095374,"issuer":{"id":11574,"kind":"organization","name":"Akouos, Inc.","symbol":"AKUS"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-07-01T17:45:07.000Z","date":"2020-06-30","kind":"exercise","acquired":true,"shares":1199976,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F4","text":"On June 30, 2020, the Series B Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series B Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"On June 30, 2020, the Series B Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series B Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 shares in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":3705972,"source":{"system":"sec-edgar","filing":"0001209191-20-039849","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1722271/000120919120039849/doc4.xml","form_type":"4"}},{"id":3095373,"issuer":{"id":11574,"kind":"organization","name":"Akouos, Inc.","symbol":"AKUS"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-07-01T17:45:07.000Z","date":"2020-06-30","kind":"exercise","acquired":true,"shares":1992238,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F3","text":"On June 30, 2020, the Series A Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"On June 30, 2020, the Series A Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series A Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 shares in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":2505996,"source":{"system":"sec-edgar","filing":"0001209191-20-039849","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1722271/000120919120039849/doc4.xml","form_type":"4"}},{"id":3095372,"issuer":{"id":11574,"kind":"organization","name":"Akouos, Inc.","symbol":"AKUS"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-07-01T17:45:07.000Z","date":"2020-06-30","kind":"exercise","acquired":true,"shares":513758,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"On June 30, 2020, the Series Seed Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series Seed Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On June 30, 2020, the Series Seed Preferred Stock converted into Common Stock on a 21.073-for-1 basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series Seed Preferred Stock was convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners 16\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the NEA 16 shares in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":513758,"source":{"system":"sec-edgar","filing":"0001209191-20-039849","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1722271/000120919120039849/doc4.xml","form_type":"4"}},{"id":3178002,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Call Option (right to buy)","published_at":"2020-04-13T21:26:04.000Z","date":"2020-04-03","kind":"other","acquired":false,"shares":1500000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The call option became exercisable upon the closing of the Issuer's initial public offering."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"derivative":{"exercise_price":0.001,"exercise_date":"2019-05-09","expiration_date":"2022-05-06","underlying":"Common Stock","underlying_shares":1500000},"source":{"system":"sec-edgar","filing":"0001209191-20-024314","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120024314/doc4.xml","form_type":"4"}},{"id":3178001,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-04-13T21:26:04.000Z","date":"2020-04-03","kind":"sale","acquired":false,"shares":564,"price":2.66,"value":1500.24,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F2","text":"On April 3, 2020, NEA 16 exercised a call option to purchase 1,500,000 shares of the Issuer's common stock (\"Common Stock\") for $0.001 per share. NEA 16 paid the exercise price through the forfeiture of 564 shares of Common Stock."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":5937998,"source":{"system":"sec-edgar","filing":"0001209191-20-024314","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120024314/doc4.xml","form_type":"4"}},{"id":3178000,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-04-13T21:26:04.000Z","date":"2020-04-03","kind":"other","acquired":true,"shares":1500000,"price":0.001,"value":1500.0,"ownership":{"direct":true},"footnotes":[{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":5938562,"source":{"system":"sec-edgar","filing":"0001209191-20-024314","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120024314/doc4.xml","form_type":"4"}},{"id":3331378,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A-2 Convertible Preferred Stock","published_at":"2019-12-26T16:57:08.000Z","date":"2019-12-24","kind":"purchase","acquired":true,"shares":900900,"price":6.66,"value":5999994.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F4","text":"Each share of Class A-2 Convertible Preferred Stock, par value $0.001 per share (\"Class A-2 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of the Issuer at a rate of 10 shares of Common Stock for each share of Class A-2 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-2 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-2 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"kind","element":"transactionCoding","label":"F3","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated May 3, 2019 with a closing date of December 24, 2019."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F4","text":"Each share of Class A-2 Convertible Preferred Stock, par value $0.001 per share (\"Class A-2 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of the Issuer at a rate of 10 shares of Common Stock for each share of Class A-2 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-2 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-2 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F5","text":"Each share of Class A-1 Convertible Preferred Stock, par value $0.001 per share (\"Class A-1 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of the Issuer at a rate of 10 shares of Common Stock for each share of Class A-1 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-1 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-1 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\")."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":900900,"derivative":{"exercise_date":"2019-12-24","underlying":"Common Stock","underlying_shares":9009000},"source":{"system":"sec-edgar","filing":"0001209191-19-061963","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119061963/doc4.xml","form_type":"4"}},{"id":3331377,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock Purchase Warrant (Right to Buy)","published_at":"2019-12-26T16:57:08.000Z","date":"2019-12-24","kind":"purchase","acquired":true,"shares":9009000,"price":0.125,"value":1126125.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F3","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated May 3, 2019 with a closing date of December 24, 2019."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\")."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":9009000,"derivative":{"exercise_price":0.666,"exercise_date":"2019-12-24","expiration_date":"2024-12-24","underlying":"Common Stock","underlying_shares":9009000},"source":{"system":"sec-edgar","filing":"0001209191-19-061963","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119061963/doc4.xml","form_type":"4"}},{"id":3456799,"issuer":{"id":2416,"kind":"organization","name":"Mirum Pharmaceuticals, Inc.","symbol":"MIRM"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A Preferred Stock","published_at":"2019-07-24T20:51:16.000Z","date":"2019-07-22","kind":"exercise","acquired":false,"shares":29889945,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Automatic conversion, in connection with the Issuer's initial public offering, of each share of the Issuer's Series A preferred stock into 0.125\nshares of the Issuer's common stock. The shares have no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Automatic conversion, in connection with the Issuer's initial public offering, of each share of the Issuer's Series A preferred stock into 0.125\nshares of the Issuer's common stock. The shares have no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Automatic conversion, in connection with the Issuer's initial public offering, of each share of the Issuer's Series A preferred stock into 0.125\nshares of the Issuer's common stock. The shares have no expiration date."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F1","text":"Automatic conversion, in connection with the Issuer's initial public offering, of each share of the Issuer's Series A preferred stock into 0.125\nshares of the Issuer's common stock. The shares have no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers\nof NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The\nindividual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad\nMakhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim\nbeneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the\nshares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":3736243},"source":{"system":"sec-edgar","filing":"0001209191-19-043052","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1759425/000120919119043052/doc4.xml","form_type":"4"}},{"id":3456798,"issuer":{"id":2416,"kind":"organization","name":"Mirum Pharmaceuticals, Inc.","symbol":"MIRM"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2019-07-24T20:51:16.000Z","date":"2019-07-22","kind":"purchase","acquired":true,"shares":450000,"price":15,"value":6750000.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F3","text":"The shares were purchased in the Issuer's initial public offering."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers\nof NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The\nindividual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad\nMakhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim\nbeneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the\nshares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":4186243,"source":{"system":"sec-edgar","filing":"0001209191-19-043052","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1759425/000120919119043052/doc4.xml","form_type":"4"}},{"id":3456797,"issuer":{"id":2416,"kind":"organization","name":"Mirum Pharmaceuticals, Inc.","symbol":"MIRM"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2019-07-24T20:51:16.000Z","date":"2019-07-22","kind":"exercise","acquired":true,"shares":3736243,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Automatic conversion, in connection with the Issuer's initial public offering, of each share of the Issuer's Series A preferred stock into 0.125\nshares of the Issuer's common stock. The shares have no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Automatic conversion, in connection with the Issuer's initial public offering, of each share of the Issuer's Series A preferred stock into 0.125\nshares of the Issuer's common stock. The shares have no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers\nof NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The\nindividual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad\nMakhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim\nbeneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the\nshares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":3736243,"source":{"system":"sec-edgar","filing":"0001209191-19-043052","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1759425/000120919119043052/doc4.xml","form_type":"4"}},{"id":3478781,"issuer":{"id":12635,"kind":"organization","name":"GENOCEA BIOSCIENCES, INC.","symbol":"GNCA"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2019-06-25T16:48:21.000Z","date":"2019-06-24","kind":"purchase","acquired":true,"shares":2857142,"price":3.5,"value":9999997.0,"ownership":{"direct":true},"footnotes":[{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"On May 22, 2019 the issuer effected a 1-for-8 reverse stock split of its common stock (the \"Reverse Stock Split\").  The amount of securities reported on this Form 4 have been adjusted to reflect the Reverse Stock Split."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell and Peter W. Sonsini. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":7225676,"source":{"system":"sec-edgar","filing":"0001209191-19-038946","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119038946/doc4.xml","form_type":"4"}},{"id":3530002,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series C Preferred Stock","published_at":"2019-05-13T17:10:44.000Z","date":"2019-05-09","kind":"exercise","acquired":false,"shares":17099315,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"On May 9, 2019, the Series C Preferred Stock, and the dividends that had accrued thereon to date, converted into Common Stock on a 9.5-for-one basis without payment of further consideration automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"On May 9, 2019, the Series C Preferred Stock, and the dividends that had accrued thereon to date, converted into Common Stock on a 9.5-for-one basis without payment of further consideration automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"On May 9, 2019, the Series C Preferred Stock, and the dividends that had accrued thereon to date, converted into Common Stock on a 9.5-for-one basis without payment of further consideration automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":1938562},"source":{"system":"sec-edgar","filing":"0001209191-19-029388","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119029388/doc4.xml","form_type":"4"}},{"id":3530001,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2019-05-13T17:10:44.000Z","date":"2019-05-09","kind":"purchase","acquired":true,"shares":1500000,"price":10,"value":15000000.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F3","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated May 6, 2019 with a closing date of May 9, 2019."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":4438562,"source":{"system":"sec-edgar","filing":"0001209191-19-029388","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119029388/doc4.xml","form_type":"4"}},{"id":3530000,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2019-05-13T17:10:44.000Z","date":"2019-05-09","kind":"purchase","acquired":true,"shares":1000000,"price":10,"value":10000000.0,"ownership":{"direct":true},"footnotes":[{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":2938562,"source":{"system":"sec-edgar","filing":"0001209191-19-029388","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119029388/doc4.xml","form_type":"4"}},{"id":3529999,"issuer":{"id":4387,"kind":"organization","name":"Trevi Therapeutics, Inc.","symbol":"TRVI"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2019-05-13T17:10:44.000Z","date":"2019-05-09","kind":"exercise","acquired":true,"shares":1938562,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On May 9, 2019, the Series C Preferred Stock, and the dividends that had accrued thereon to date, converted into Common Stock on a 9.5-for-one basis without payment of further consideration automatically upon the closing of the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":1938562,"source":{"system":"sec-edgar","filing":"0001209191-19-029388","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119029388/doc4.xml","form_type":"4"}},{"id":3533690,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A-1 Convertible Preferred Stock","published_at":"2019-05-09T18:02:01.000Z","date":"2019-05-07","kind":"purchase","acquired":true,"shares":256700,"price":10.8,"value":2772360.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F4","text":"Each share of Class A-1 Convertible Preferred Stock, par value $0.001 per share (\"Class A-1 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of the Issuer at a rate of 10 shares of Common Stock for each share of Class A-1 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-1 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-1 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated May 3, 2019 with a closing date of May 7, 2019."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F4","text":"Each share of Class A-1 Convertible Preferred Stock, par value $0.001 per share (\"Class A-1 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of the Issuer at a rate of 10 shares of Common Stock for each share of Class A-1 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-1 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-1 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F4","text":"Each share of Class A-1 Convertible Preferred Stock, par value $0.001 per share (\"Class A-1 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of the Issuer at a rate of 10 shares of Common Stock for each share of Class A-1 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-1 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-1 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\")."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":256700,"derivative":{"exercise_date":"2019-05-07","underlying":"Common Stock","underlying_shares":2567000},"source":{"system":"sec-edgar","filing":"0001209191-19-028589","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119028589/doc4.xml","form_type":"4"}},{"id":3533689,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock Purchase Warrant (Right to Buy)","published_at":"2019-05-09T18:02:01.000Z","date":"2019-05-07","kind":"purchase","acquired":true,"shares":3703704,"price":0.125,"value":462963.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated May 3, 2019 with a closing date of May 7, 2019."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\")."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":3703704,"derivative":{"exercise_price":1.08,"exercise_date":"2019-05-07","expiration_date":"2024-05-07","underlying":"Common Stock","underlying_shares":3703704},"source":{"system":"sec-edgar","filing":"0001209191-19-028589","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119028589/doc4.xml","form_type":"4"}},{"id":3533688,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2019-05-09T18:02:01.000Z","date":"2019-05-07","kind":"purchase","acquired":true,"shares":1136704,"price":1.08,"value":1227640.32,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated May 3, 2019 with a closing date of May 7, 2019."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\")."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":2052454,"source":{"system":"sec-edgar","filing":"0001209191-19-028589","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119028589/doc4.xml","form_type":"4"}},{"id":3650177,"issuer":{"id":12635,"kind":"organization","name":"GENOCEA BIOSCIENCES, INC.","symbol":"GNCA"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Warrant to Purchase Common Stock","published_at":"2019-02-19T17:00:29.000Z","date":"2019-02-14","kind":"purchase","acquired":true,"shares":2487067,"price":0.125,"value":310883.375,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the issuer pursuant to a Subscription Agreement dated February 11, 2019, with a closing date of February 14, 2019."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell and Peter W. Sonsini. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":2487067,"derivative":{"exercise_price":0.5656,"exercise_date":"2019-02-14","expiration_date":"2024-02-14","underlying":"Common Stock","underlying_shares":2487067},"source":{"system":"sec-edgar","filing":"0001209191-19-011145","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119011145/doc4.xml","form_type":"4"}},{"id":3650176,"issuer":{"id":12635,"kind":"organization","name":"GENOCEA BIOSCIENCES, INC.","symbol":"GNCA"},"owners":[{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":1,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":2,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":3,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2019-02-19T17:00:29.000Z","date":"2019-02-14","kind":"purchase","acquired":true,"shares":9948269,"price":0.4713,"value":4688619.1797,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the issuer pursuant to a Subscription Agreement dated February 11, 2019, with a closing date of February 14, 2019."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The shares are directly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), and indirectly held by NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\").The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell and Peter W. Sonsini. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the shares of the Issuer held by NEA 16 in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":34948269,"source":{"system":"sec-edgar","filing":"0001209191-19-011145","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119011145/doc4.xml","form_type":"4"}}]}