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This transaction was made pursuant to a Rule 10b5-1 trading plan in the form of a durable sell-to-cover instruction adopted prior to the 2023 amendments to Rule 10b5-1. The trading plan provides for the automatic sale of shares of common stock necessary to satisfy the reporting person's tax withholding obligations incurred in connection with the vesting of RSUs."},{"field":"shares","element":"transactionShares","label":"F2","text":"Reflects the number of shares of common stock that were sold in a \"sell-to-cover\" transaction for the sole purpose of satisfying tax withholding obligations in connection with the vesting of RSUs previously granted to the reporting person and\ndoes not represent a discretionary trade by the reporting person. This transaction was made pursuant to a Rule 10b5-1 trading plan in the form of a durable sell-to-cover instruction adopted prior to the 2023 amendments to Rule 10b5-1. The trading plan provides for the automatic sale of shares of common stock necessary to satisfy the reporting person's tax withholding obligations incurred in connection with the vesting of RSUs."}],"balance_after":104998,"source":{"system":"sec-edgar","filing":"0001891113-26-000002","document":"wk-form4_1771984441.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1619856/000189111326000002/wk-form4_1771984441.xml","form_type":"4"}},{"id":883919,"issuer":{"id":6445,"kind":"organization","name":"Caribou Biosciences, Inc."},"owners":[{"id":64893,"kind":"person","name":"Khan Ruhi Ahmad","position":1,"cik":"0001891113","reported_name":"Khan Ruhi Ahmad","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Business Officer"}}],"security":"Common Stock","published_at":"2026-02-25T01:54:04.000Z","date":"2026-02-20","kind":"grant","planned":false,"acquired":true,"shares":45000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This reflects restricted stock units (\"RSUs\") that vest in four equal annual installments beginning on February 20, 2027, subject to the reporting person continuing to provide service to the Issuer through the applicable vesting dates. 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This transaction was made pursuant to a Rule 10b5-1 trading plan in the form of a durable sell-to-cover instruction adopted prior to the 2023 amendments to Rule 10b5-1. The trading plan provides for the automatic sale of shares of common stock necessary to satisfy the reporting person's tax withholding obligations incurred in connection with the vesting of RSUs."},{"field":"shares","element":"transactionShares","label":"F2","text":"Reflects the number of shares of common stock that were sold in a \"sell to cover\" transaction for the sole purpose of satisfying tax withholding obligations in connection with the vesting of RSUs previously granted to the reporting person and does not represent a discretionary trade by the reporting person. This transaction was made pursuant to a Rule 10b5-1 trading plan in the form of a durable sell-to-cover instruction adopted prior to the 2023 amendments to Rule 10b5-1. The trading plan provides for the automatic sale of shares of common stock necessary to satisfy the reporting person's tax withholding obligations incurred in connection with the vesting of RSUs."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"This transaction was executed in multiple trades on 2/21/2025 at prices ranging from $1.32 to $1.35. The price reported above reflects the weighted average sale price. The reporting person hereby undertakes to provide upon request by the staff of the Securities and Exchange Commission, the Issuer, or a security holder of the Issuer, full information regarding the number of shares sold at each separate price within the specified range."}],"balance_after":66936,"source":{"system":"sec-edgar","filing":"0001891113-25-000003","document":"wk-form4_1740187160.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1619856/000189111325000003/wk-form4_1740187160.xml","form_type":"4"}},{"id":1252247,"issuer":{"id":6445,"kind":"organization","name":"Caribou Biosciences, Inc."},"owners":[{"id":64893,"kind":"person","name":"Khan Ruhi Ahmad","position":1,"cik":"0001891113","reported_name":"Khan Ruhi Ahmad","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Business Officer"}}],"security":"Common Stock","published_at":"2025-02-22T01:19:26.000Z","date":"2025-02-20","kind":"grant","planned":false,"acquired":true,"shares":37500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This reflects restricted stock units (\"RSUs\") that vest in four equal annual installments beginning on February 20, 2026, subject to the reporting person's continued services to the Issuer through the applicable vesting dates. 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