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The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":180093,"source":{"system":"sec-edgar","filing":"0001958523-26-000003","document":"form4-03042026_040336.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1528115/000195852326000003/form4-03042026_040336.xml","form_type":"4"}},{"id":887590,"issuer":{"id":5011,"kind":"organization","name":"Annexon, Inc.","symbol":"ANNX"},"owners":[{"id":62768,"kind":"person","name":"ARTIS DEAN RICHARD","position":1,"cik":"0001958523","reported_name":"ARTIS DEAN RICHARD","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP & CHIEF SCIENTIFIC OFFICER"}}],"security":"Stock Option (Right to Buy)","published_at":"2026-02-24T00:07:27.000Z","date":"2026-02-19","kind":"grant","planned":false,"acquired":true,"shares":250000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"1/48th of the shares subject to the option vest on each monthly anniversary measured from February 19, 2026 (the \"Vesting Commencement Date\"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date, subject to Reporting Person's continuous service with the Issuer as of each such vesting date."}],"balance_after":250000,"derivative":{"exercise_price":5.1,"expiration_date":"2036-02-19","underlying":"Common Stock","underlying_shares":250000},"source":{"system":"sec-edgar","filing":"0001958523-26-000002","document":"form4-02242026_120223.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1528115/000195852326000002/form4-02242026_120223.xml","form_type":"4"}},{"id":887589,"issuer":{"id":5011,"kind":"organization","name":"Annexon, Inc.","symbol":"ANNX"},"owners":[{"id":62768,"kind":"person","name":"ARTIS DEAN RICHARD","position":1,"cik":"0001958523","reported_name":"ARTIS DEAN RICHARD","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP & CHIEF SCIENTIFIC OFFICER"}}],"security":"Common Stock","published_at":"2026-02-24T00:07:27.000Z","date":"2026-02-19","kind":"grant","planned":false,"acquired":true,"shares":62500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Constitute restricted stock units (\"RSUs\") for which the Reporting Person is entitled to receive one (1) share of Common Stock for each RSU upon vesting. 1/3rd of the RSUs vest annually on February 19 of each year, with the first 1/3rd vesting on February 19, 2027, subject to Reporting Person's continuous service with the Issuer as of each such vesting date."}],"balance_after":185987,"source":{"system":"sec-edgar","filing":"0001958523-26-000002","document":"form4-02242026_120223.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1528115/000195852326000002/form4-02242026_120223.xml","form_type":"4"}},{"id":890285,"issuer":{"id":5011,"kind":"organization","name":"Annexon, Inc.","symbol":"ANNX"},"owners":[{"id":62768,"kind":"person","name":"ARTIS DEAN RICHARD","position":1,"cik":"0001958523","reported_name":"ARTIS DEAN RICHARD","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP & CHIEF SCIENTIFIC OFFICER"}}],"security":"Common Stock","published_at":"2026-02-20T21:30:13.000Z","date":"2026-02-18","kind":"sale","planned":false,"acquired":false,"shares":5290,"price":5.1,"value":26979.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold to cover tax withholding obligations in connection with the vesting of restricted stock units (\"RSUs\")."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"This transaction was executed in multiple trades in prices ranging from $4.925 to $5.155, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":123487,"source":{"system":"sec-edgar","filing":"0001958523-26-000001","document":"form4-02202026_040209.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1528115/000195852326000001/form4-02202026_040209.xml","form_type":"4"}},{"id":1235292,"issuer":{"id":5011,"kind":"organization","name":"Annexon, Inc.","symbol":"ANNX"},"owners":[{"id":62768,"kind":"person","name":"ARTIS DEAN RICHARD","position":1,"cik":"0001958523","reported_name":"ARTIS DEAN RICHARD","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP & CHIEF SCIENTIFIC OFFICER"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-03-03T21:56:38.000Z","date":"2025-02-27","kind":"grant","planned":false,"acquired":true,"shares":272575,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"1/48th of the shares subject to the option vest on each monthly anniversary measured from February 27, 2025 (the \"Vesting Commencement Date\"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date."}],"balance_after":272575,"derivative":{"exercise_price":2.5,"expiration_date":"2034-02-27","underlying":"Common Stock","underlying_shares":272575},"source":{"system":"sec-edgar","filing":"0001415889-25-006196","document":"form4-03032025_090332.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1528115/000141588925006196/form4-03032025_090332.xml","form_type":"4"}},{"id":1235291,"issuer":{"id":5011,"kind":"organization","name":"Annexon, Inc.","symbol":"ANNX"},"owners":[{"id":62768,"kind":"person","name":"ARTIS DEAN RICHARD","position":1,"cik":"0001958523","reported_name":"ARTIS DEAN RICHARD","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP & CHIEF SCIENTIFIC OFFICER"}}],"security":"Common Stock","published_at":"2025-03-03T21:56:38.000Z","date":"2024-02-27","kind":"grant","planned":false,"acquired":true,"shares":44963,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Constitute restricted stock units (\"RSUs\") for which the Reporting Person is entitled to receive one (1) share of Common Stock for each RSU upon vesting. 1/3rd of the RSUs vest annually on February 27 of each year, with the first 1/3rd vesting on February 27, 2026."}],"balance_after":128777,"source":{"system":"sec-edgar","filing":"0001415889-25-006196","document":"form4-03032025_090332.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1528115/000141588925006196/form4-03032025_090332.xml","form_type":"4"}},{"id":1255189,"issuer":{"id":5011,"kind":"organization","name":"Annexon, Inc.","symbol":"ANNX"},"owners":[{"id":62768,"kind":"person","name":"ARTIS DEAN RICHARD","position":1,"cik":"0001958523","reported_name":"ARTIS DEAN RICHARD","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP & CHIEF SCIENTIFIC OFFICER"}}],"security":"Common Stock","published_at":"2025-02-20T21:52:34.000Z","date":"2025-02-18","kind":"sale","planned":false,"acquired":false,"shares":5515,"price":2.97,"value":16379.55,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold to cover tax withholding obligations in connection with the vesting of restricted stock units (\"RSUs\")."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"This transaction was executed in multiple trades in prices ranging from $2.86 to $3.1376, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":83814,"source":{"system":"sec-edgar","filing":"0001415889-25-004889","document":"form4-02202025_090227.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1528115/000141588925004889/form4-02202025_090227.xml","form_type":"4"}},{"id":1628188,"issuer":{"id":5011,"kind":"organization","name":"Annexon, Inc.","symbol":"ANNX"},"owners":[{"id":62768,"kind":"person","name":"ARTIS DEAN RICHARD","position":1,"cik":"0001958523","reported_name":"ARTIS DEAN RICHARD","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP & CHIEF SCIENTIFIC OFFICER"}}],"security":"Stock Option (Right to Buy)","published_at":"2024-02-21T21:32:02.000Z","date":"2024-02-16","kind":"grant","planned":false,"acquired":true,"shares":160000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"1/48th of the shares subject to the option vest on each monthly anniversary measured from February 16, 2024 (the \"Vesting Commencement Date\"), such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date."}],"balance_after":160000,"derivative":{"exercise_price":5.13,"expiration_date":"2034-02-16","underlying":"Common Stock","underlying_shares":160000},"source":{"system":"sec-edgar","filing":"0001415889-24-004626","document":"form4-02212024_040220.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1528115/000141588924004626/form4-02212024_040220.xml","form_type":"4"}},{"id":1628187,"issuer":{"id":5011,"kind":"organization","name":"Annexon, Inc.","symbol":"ANNX"},"owners":[{"id":62768,"kind":"person","name":"ARTIS DEAN RICHARD","position":1,"cik":"0001958523","reported_name":"ARTIS DEAN RICHARD","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP & CHIEF SCIENTIFIC OFFICER"}}],"security":"Common Stock","published_at":"2024-02-21T21:32:02.000Z","date":"2024-02-16","kind":"grant","planned":false,"acquired":true,"shares":39000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Constitute restricted stock units (\"RSUs\") for which the Reporting Person is entitled to receive one (1) share of Common Stock for each RSU upon vesting. 1/3rd of the RSUs vest annually on February 16 of each year, with the first 1/3rd vesting on February 16, 2025."}],"balance_after":89329,"source":{"system":"sec-edgar","filing":"0001415889-24-004626","document":"form4-02212024_040220.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1528115/000141588924004626/form4-02212024_040220.xml","form_type":"4"}},{"id":2052122,"issuer":{"id":5011,"kind":"organization","name":"Annexon, Inc.","symbol":"ANNX"},"owners":[{"id":62768,"kind":"person","name":"ARTIS DEAN RICHARD","position":1,"cik":"0001958523","reported_name":"ARTIS DEAN RICHARD","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP & Chief Scientific Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2023-01-19T00:43:23.000Z","date":"2023-01-15","kind":"grant","acquired":true,"shares":210000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"25% of the shares subject to the option vest on the first anniversary measured from January 6, 2023 (the \"Vesting Commencement Date\"), and 1/48th of the total number of shares vest monthly thereafter, such that 100% of the shares subject to the option will be fully vested and exercisable on the fourth anniversary of the Vesting Commencement Date."}],"balance_after":210000,"derivative":{"exercise_price":6.84,"expiration_date":"2033-01-15","underlying":"Common Stock","underlying_shares":210000},"source":{"system":"sec-edgar","filing":"0001567619-23-000998","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1528115/000156761923000998/doc1.xml","form_type":"4"}}]}