{"transactions":[{"id":830926,"issuer":{"id":1085,"kind":"organization","name":"AN2 Therapeutics, Inc.","symbol":"ANTX"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2026-03-23T23:04:19.000Z","date":"2026-03-19","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":23742,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option is fully vested."}],"balance_after":0,"derivative":{"exercise_price":5.91,"expiration_date":"2033-06-06","underlying":"Common Stock","underlying_shares":23742},"source":{"system":"sec-edgar","filing":"0001193125-26-120207","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1880438/000119312526120207/ownership.xml","form_type":"4"}},{"id":830925,"issuer":{"id":1085,"kind":"organization","name":"AN2 Therapeutics, Inc.","symbol":"ANTX"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2026-03-23T23:04:19.000Z","date":"2026-03-19","kind":"grant","planned":false,"acquired":true,"shares":23742,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"The exercise price of the option is $3.91 per share, representing the closing price of the Issuer's common stock on the date of the repricing; provided that the exercise price will be increased to the original exercise price before repricing if, prior to the \"Premium End Date\" (as defined below), the repriced option is exercised or the Reporting Person's services with the Company is terminated. The \"Premium End Date\" means the earliest of: (i) September 19, 2027, (ii) the date of a change in control or (iii) the Reporting Person's death or disability."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option is fully vested."}],"balance_after":23742,"derivative":{"exercise_price":3.91,"expiration_date":"2033-06-06","underlying":"Common Stock","underlying_shares":23742},"source":{"system":"sec-edgar","filing":"0001193125-26-120207","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1880438/000119312526120207/ownership.xml","form_type":"4"}},{"id":830924,"issuer":{"id":1085,"kind":"organization","name":"AN2 Therapeutics, Inc.","symbol":"ANTX"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2026-03-23T23:04:19.000Z","date":"2026-03-19","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":10362,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option is fully vested."}],"balance_after":0,"derivative":{"exercise_price":17.28,"expiration_date":"2032-05-11","underlying":"Common Stock","underlying_shares":10362},"source":{"system":"sec-edgar","filing":"0001193125-26-120207","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1880438/000119312526120207/ownership.xml","form_type":"4"}},{"id":830923,"issuer":{"id":1085,"kind":"organization","name":"AN2 Therapeutics, Inc.","symbol":"ANTX"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2026-03-23T23:04:19.000Z","date":"2026-03-19","kind":"grant","planned":false,"acquired":true,"shares":10362,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"The exercise price of the option is $3.91 per share, representing the closing price of the Issuer's common stock on the date of the repricing; provided that the exercise price will be increased to the original exercise price before repricing if, prior to the \"Premium End Date\" (as defined below), the repriced option is exercised or the Reporting Person's services with the Company is terminated. The \"Premium End Date\" means the earliest of: (i) September 19, 2027, (ii) the date of a change in control or (iii) the Reporting Person's death or disability."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option is fully vested."}],"balance_after":10362,"derivative":{"exercise_price":3.91,"expiration_date":"2032-05-11","underlying":"Common Stock","underlying_shares":10362},"source":{"system":"sec-edgar","filing":"0001193125-26-120207","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1880438/000119312526120207/ownership.xml","form_type":"4"}},{"id":830922,"issuer":{"id":1085,"kind":"organization","name":"AN2 Therapeutics, Inc.","symbol":"ANTX"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2026-03-23T23:04:19.000Z","date":"2026-03-19","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":16941,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option is fully vested."}],"balance_after":0,"derivative":{"exercise_price":9.308,"expiration_date":"2032-02-17","underlying":"Common Stock","underlying_shares":16941},"source":{"system":"sec-edgar","filing":"0001193125-26-120207","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1880438/000119312526120207/ownership.xml","form_type":"4"}},{"id":830921,"issuer":{"id":1085,"kind":"organization","name":"AN2 Therapeutics, Inc.","symbol":"ANTX"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2026-03-23T23:04:19.000Z","date":"2026-03-19","kind":"grant","planned":false,"acquired":true,"shares":16941,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"The exercise price of the option is $3.91 per share, representing the closing price of the Issuer's common stock on the date of the repricing; provided that the exercise price will be increased to the original exercise price before repricing if, prior to the \"Premium End Date\" (as defined below), the repriced option is exercised or the Reporting Person's services with the Company is terminated. The \"Premium End Date\" means the earliest of: (i) September 19, 2027, (ii) the date of a change in control or (iii) the Reporting Person's death or disability."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"On March 19, 2026, the board of directors of the Issuer approved the repricing of the option. Except as further described in footnote 1, all other terms of the option remain unchanged."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option is fully vested."}],"balance_after":16941,"derivative":{"exercise_price":3.91,"expiration_date":"2032-02-17","underlying":"Common Stock","underlying_shares":16941},"source":{"system":"sec-edgar","filing":"0001193125-26-120207","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1880438/000119312526120207/ownership.xml","form_type":"4"}},{"id":888254,"issuer":{"id":1085,"kind":"organization","name":"AN2 Therapeutics, Inc.","symbol":"ANTX"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2026-02-23T21:21:56.000Z","date":"2026-02-20","kind":"grant","planned":false,"acquired":true,"shares":20400,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option shares shall vest on February 20, 2027, subject to the Reporting Person providing continuous service through such date."}],"balance_after":20400,"derivative":{"exercise_price":1.04,"expiration_date":"2036-02-19","underlying":"Common Stock","underlying_shares":20400},"source":{"system":"sec-edgar","filing":"0001193125-26-064061","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1880438/000119312526064061/ownership.xml","form_type":"4"}},{"id":1135579,"issuer":{"id":1085,"kind":"organization","name":"AN2 Therapeutics, Inc.","symbol":"ANTX"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-05-23T20:57:19.000Z","date":"2025-05-22","kind":"grant","planned":false,"acquired":true,"shares":19111,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option shares shall vest on March 31, 2026, subject to the Reporting Person providing continuous service through such date."}],"balance_after":19111,"derivative":{"exercise_price":1.19,"expiration_date":"2035-05-21","underlying":"Common Stock","underlying_shares":19111},"source":{"system":"sec-edgar","filing":"0000950170-25-077058","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1880438/000095017025077058/ownership.xml","form_type":"4"}},{"id":1472247,"issuer":{"id":1085,"kind":"organization","name":"AN2 Therapeutics, Inc.","symbol":"ANTX"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2024-06-21T21:58:43.000Z","date":"2024-06-19","kind":"grant","planned":false,"acquired":true,"shares":64503,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option shares shall vest on the earlier of (a) the one-year anniversary of June 19, 2024 or (b) the day prior to the date of the Issuer's next annual stockholder meeting, subject to the Reporting Person providing continuous service through such vesting date."}],"balance_after":64503,"derivative":{"exercise_price":2,"expiration_date":"2034-06-18","underlying":"Common Stock","underlying_shares":64503},"source":{"system":"sec-edgar","filing":"0000950170-24-076374","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1880438/000095017024076374/ownership.xml","form_type":"4"}},{"id":1860914,"issuer":{"id":1085,"kind":"organization","name":"AN2 Therapeutics, Inc.","symbol":"ANTX"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option\n(right to buy)","published_at":"2023-06-10T00:37:42.000Z","date":"2023-06-07","kind":"grant","planned":false,"acquired":true,"shares":23742,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option shares shall vest on the earlier of (a) the one-year anniversary of June 7, 2023 or (b) the day prior to the date of the Issuer's next annual stockholder meeting, subject to the Reporting Person providing continuous service through such vesting date."}],"balance_after":23742,"derivative":{"exercise_price":5.91,"expiration_date":"2033-06-06","underlying":"Common Stock","underlying_shares":23742},"source":{"system":"sec-edgar","filing":"0000899243-23-015310","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1880438/000089924323015310/doc4.xml","form_type":"4"}},{"id":2270599,"issuer":{"id":1085,"kind":"organization","name":"AN2 Therapeutics, Inc.","symbol":"ANTX"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2022-05-17T01:18:56.000Z","date":"2022-05-12","kind":"grant","acquired":true,"shares":10362,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option vest as follows: 1/12 of the shares shall vest on each monthly anniversary as measured from March 25, 2022."}],"balance_after":10362,"derivative":{"exercise_price":17.28,"expiration_date":"2032-05-11","underlying":"Common Stock","underlying_shares":10362},"source":{"system":"sec-edgar","filing":"0000899243-22-018281","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1880438/000089924322018281/doc4.xml","form_type":"4"}},{"id":3841444,"issuer":{"id":164269,"kind":"organization","name":"SYNERGY PHARMACEUTICALS, INC.","symbol":"SGYP"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Options","published_at":"2018-08-16T17:00:57.000Z","date":"2018-08-15","kind":"exercise","acquired":false,"shares":150000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"Options became exercisable on 8/21/2009, 2010 and 2011."}],"balance_after":474364,"derivative":{"exercise_price":1.2,"expiration_date":"2018-08-21","underlying":"Common Stock","underlying_shares":150000},"source":{"system":"sec-edgar","filing":"0001104659-18-052475","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1339901/000110465918052475/a4.xml","form_type":"4"}},{"id":3841443,"issuer":{"id":164269,"kind":"organization","name":"SYNERGY PHARMACEUTICALS, INC.","symbol":"SGYP"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2018-08-16T17:00:57.000Z","date":"2018-08-15","kind":"tax_withholding","acquired":false,"shares":101695,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents the number of shares forfeited to the Company in payment of the exercise price of the stock options."}],"balance_after":48305,"source":{"system":"sec-edgar","filing":"0001104659-18-052475","document":"a4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1339901/000110465918052475/a4.xml","form_type":"4"}},{"id":3841442,"issuer":{"id":164269,"kind":"organization","name":"SYNERGY PHARMACEUTICALS, INC.","symbol":"SGYP"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2018-08-16T17:00:57.000Z","date":"2018-08-15","kind":"exercise","acquired":true,"shares":150000,"price":1.2,"value":180000.0,"ownership":{"direct":true},"balance_after":150000,"source":{"system":"sec-edgar","filing":"0001104659-18-052475","document":"a4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1339901/000110465918052475/a4.xml","form_type":"4"}},{"id":3888198,"issuer":{"id":164269,"kind":"organization","name":"SYNERGY PHARMACEUTICALS, INC.","symbol":"SGYP"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Options","published_at":"2018-06-19T16:32:08.000Z","date":"2018-06-16","kind":"grant","acquired":true,"shares":114750,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents the annual grant of stock options to each outside independent board member of the issuer."}],"balance_after":624364,"derivative":{"exercise_price":1.8,"exercise_date":"2019-06-16","expiration_date":"2028-06-16","underlying":"Common Stock","underlying_shares":114750},"source":{"system":"sec-edgar","filing":"0001104659-18-041066","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1339901/000110465918041066/a4.xml","form_type":"4"}},{"id":3915808,"issuer":{"id":152552,"kind":"organization","name":"MEDICINES CO /DE","symbol":"MDCO"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right-to-buy)","published_at":"2018-05-29T17:03:43.000Z","date":"2018-05-25","kind":"exercise","acquired":false,"shares":7500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vested in twelve equal monthly installments beginning June 29, 2008."}],"balance_after":0,"derivative":{"exercise_price":18.3,"expiration_date":"2018-05-29","underlying":"Common Stock","underlying_shares":7500},"source":{"system":"sec-edgar","filing":"0001179110-18-007621","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1113481/000117911018007621/edgar.xml","form_type":"4"}},{"id":3915807,"issuer":{"id":152552,"kind":"organization","name":"MEDICINES CO /DE","symbol":"MDCO"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2018-05-29T17:03:43.000Z","date":"2018-05-25","kind":"sale","acquired":false,"shares":7500,"price":32.2,"value":241500.0,"ownership":{"direct":true},"balance_after":53133,"source":{"system":"sec-edgar","filing":"0001179110-18-007621","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1113481/000117911018007621/edgar.xml","form_type":"4"}},{"id":3915806,"issuer":{"id":152552,"kind":"organization","name":"MEDICINES CO /DE","symbol":"MDCO"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2018-05-29T17:03:43.000Z","date":"2018-05-25","kind":"exercise","acquired":true,"shares":7500,"price":18.3,"value":137250.0,"ownership":{"direct":true},"balance_after":60633,"source":{"system":"sec-edgar","filing":"0001179110-18-007621","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1113481/000117911018007621/edgar.xml","form_type":"4"}},{"id":4268997,"issuer":{"id":164269,"kind":"organization","name":"SYNERGY PHARMACEUTICALS, INC.","symbol":"SGYP"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Options","published_at":"2017-06-30T17:08:53.000Z","date":"2017-06-28","kind":"grant","acquired":true,"shares":12000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The reported transactions with this same footnote involved an amendment of an outstanding option, resulting in the deemed cancellation of the old option and the grant of a replacement option. The old option was originally granted on November 20, 2009. The vesting schedule of the old option was reported on a Form 3 filed by the reporting person on August 3, 2011."}],"balance_after":509614,"derivative":{"exercise_price":1.4,"exercise_date":"2017-06-28","expiration_date":"2019-11-20","underlying":"Common Stock","underlying_shares":12000},"source":{"system":"sec-edgar","filing":"0001104659-17-043012","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1339901/000110465917043012/a4.xml","form_type":"4"}},{"id":4268996,"issuer":{"id":164269,"kind":"organization","name":"SYNERGY PHARMACEUTICALS, INC.","symbol":"SGYP"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Options","published_at":"2017-06-30T17:08:53.000Z","date":"2017-06-28","kind":"disposition_to_issuer","acquired":false,"shares":12000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The reported transactions with this same footnote involved an amendment of an outstanding option, resulting in the deemed cancellation of the old option and the grant of a replacement option. The old option was originally granted on November 20, 2009. The vesting schedule of the old option was reported on a Form 3 filed by the reporting person on August 3, 2011."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The reported transactions with this same footnote involved an amendment of an outstanding option, resulting in the deemed cancellation of the old option and the grant of a replacement option. The old option was originally granted on November 20, 2009. The vesting schedule of the old option was reported on a Form 3 filed by the reporting person on August 3, 2011."}],"balance_after":497614,"derivative":{"exercise_price":1.4,"expiration_date":"2019-11-20","underlying":"Common Stock","underlying_shares":12000},"source":{"system":"sec-edgar","filing":"0001104659-17-043012","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1339901/000110465917043012/a4.xml","form_type":"4"}},{"id":4268995,"issuer":{"id":164269,"kind":"organization","name":"SYNERGY PHARMACEUTICALS, INC.","symbol":"SGYP"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Options","published_at":"2017-06-30T17:08:53.000Z","date":"2017-06-28","kind":"grant","acquired":true,"shares":62500,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":509614,"derivative":{"exercise_price":4.5,"exercise_date":"2018-06-28","expiration_date":"2027-06-28","underlying":"Common Stock","underlying_shares":62500},"source":{"system":"sec-edgar","filing":"0001104659-17-043012","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1339901/000110465917043012/a4.xml","form_type":"4"}},{"id":4301586,"issuer":{"id":152552,"kind":"organization","name":"MEDICINES CO /DE","symbol":"MDCO"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right-to-buy","published_at":"2017-05-30T19:40:09.000Z","date":"2017-05-25","kind":"grant","acquired":true,"shares":8577,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This option vests in one installment on May 25, 2018 and is made as part of and pursuant to Issuer's director compensation package."}],"balance_after":8577,"derivative":{"exercise_price":39.39,"expiration_date":"2027-05-25","underlying":"Common Stock","underlying_shares":8577},"source":{"system":"sec-edgar","filing":"0001179110-17-008214","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1113481/000117911017008214/edgar.xml","form_type":"4"}},{"id":4301585,"issuer":{"id":152552,"kind":"organization","name":"MEDICINES CO /DE","symbol":"MDCO"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2017-05-30T19:40:09.000Z","date":"2017-05-25","kind":"grant","acquired":true,"shares":3237,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This restricted stock award vests on May 25, 2018 and is made as part of and pursuant to Issuer's director compensation package."}],"balance_after":53133,"source":{"system":"sec-edgar","filing":"0001179110-17-008214","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1113481/000117911017008214/edgar.xml","form_type":"4"}},{"id":4305057,"issuer":{"id":152552,"kind":"organization","name":"MEDICINES CO /DE","symbol":"MDCO"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right-to-buy)","published_at":"2017-05-25T17:08:11.000Z","date":"2017-05-23","kind":"exercise","acquired":false,"shares":7500,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"Not applicable."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vested in twelve equal monthly installments beginning on June 24, 2007."}],"balance_after":0,"derivative":{"exercise_price":19.6,"expiration_date":"2017-05-24","underlying":"Common Stock","underlying_shares":7500},"source":{"system":"sec-edgar","filing":"0001179110-17-008011","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1113481/000117911017008011/edgar.xml","form_type":"4"}},{"id":4305056,"issuer":{"id":152552,"kind":"organization","name":"MEDICINES CO /DE","symbol":"MDCO"},"owners":[{"id":56571,"kind":"person","name":"Spigelman Melvin K","position":1,"cik":"0001339901","reported_name":"Spigelman Melvin K","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2017-05-25T17:08:11.000Z","date":"2017-05-23","kind":"exercise","acquired":true,"shares":7500,"price":19.6,"value":147000.0,"ownership":{"direct":true},"balance_after":49896,"source":{"system":"sec-edgar","filing":"0001179110-17-008011","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1113481/000117911017008011/edgar.xml","form_type":"4"}}]}