{"transactions":[{"id":785539,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Restricted Stock Units","published_at":"2026-05-11T20:37:05.000Z","date":"2026-05-07","kind":"grant","planned":false,"acquired":true,"shares":17700,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Grant of restricted stock units (RSUs) pursuant to the Integra LifeSciences Holdings Corporation (IART) Fifth Amended and Restated 2003 Equity Incentive Plan, as amended. Each RSU represents a contingent right to receive one share of IART common stock."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"RSUs vest in full on the one-year anniversary of the grant date of May 7, 2026. The reporting person elected to defer receipt of the shares underlying the RSUs. In accordance with his deferral election, vested shares will be delivered to the reporting person in one lump sum, in the calendar year next following the calendar year in which the reporting person's termination of service on the Board of Directors occurs (unless the reporting person elected a later calendar year)."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F2","text":"RSUs vest in full on the one-year anniversary of the grant date of May 7, 2026. The reporting person elected to defer receipt of the shares underlying the RSUs. In accordance with his deferral election, vested shares will be delivered to the reporting person in one lump sum, in the calendar year next following the calendar year in which the reporting person's termination of service on the Board of Directors occurs (unless the reporting person elected a later calendar year)."}],"balance_after":17700,"derivative":{"underlying":"Common Stock","underlying_shares":17700},"source":{"system":"sec-edgar","filing":"0001214496-26-000001","document":"wk-form4_1778531820.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/917520/000121449626000001/wk-form4_1778531820.xml","form_type":"4"}},{"id":1151429,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2025-05-13T20:17:40.000Z","date":"2025-05-09","kind":"grant","planned":false,"acquired":true,"shares":19592,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":90034,"source":{"system":"sec-edgar","filing":"0000917520-25-000044","document":"wk-form4_1747167452.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/917520/000091752025000044/wk-form4_1747167452.xml","form_type":"4"}},{"id":1151428,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2025-05-13T20:17:40.000Z","date":"2025-05-09","kind":"grant","planned":false,"acquired":true,"shares":6939,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":70442,"source":{"system":"sec-edgar","filing":"0000917520-25-000044","document":"wk-form4_1747167452.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/917520/000091752025000044/wk-form4_1747167452.xml","form_type":"4"}},{"id":1472187,"issuer":{"id":83618,"kind":"organization","name":"Omega Therapeutics, Inc.","symbol":"OMGA"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2024-06-21T16:20:10.000Z","date":"2024-06-20","kind":"grant","planned":false,"acquired":true,"shares":25000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The options vest and become exercisable on the earlier of (i) the date of the Issuer's next annual meeting of stockholders and (ii) the first anniversary of the date of grant, subject to the Reporting Person's continued service on the Issuer's Board of Directors through such vesting date."}],"balance_after":25000,"derivative":{"exercise_price":2.2,"expiration_date":"2034-06-19","underlying":"Common Stock","underlying_shares":25000},"source":{"system":"sec-edgar","filing":"0000950170-24-076265","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1850838/000095017024076265/ownership.xml","form_type":"4"}},{"id":1519665,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2024-05-13T20:38:09.000Z","date":"2024-05-09","kind":"grant","planned":false,"acquired":true,"shares":8696,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":63503,"source":{"system":"sec-edgar","filing":"0001628280-24-022923","document":"wk-form4_1715632673.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/917520/000162828024022923/wk-form4_1715632673.xml","form_type":"4"}},{"id":1651772,"issuer":{"id":83618,"kind":"organization","name":"Omega Therapeutics, Inc.","symbol":"OMGA"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2024-02-09T17:00:27.000Z","date":"2023-07-10","kind":"grant","planned":false,"acquired":true,"shares":36713,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests and becomes exercisable in thirty-six substantially equal monthly installments following the date of grant, such that the option shall be fully vested and exercisable on the third anniversary of the date of grant, subject to the Reporting Person's continued service on the Issuer's Board of Directors through each such vesting date."}],"balance_after":36713,"derivative":{"exercise_price":4.69,"expiration_date":"2033-07-09","underlying":"Common Stock","underlying_shares":36713},"source":{"system":"sec-edgar","filing":"0000950170-24-013362","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1850838/000095017024013362/ownership.xml","form_type":"4/A","original_submission_date":"2023-07-12"}},{"id":1651769,"issuer":{"id":83618,"kind":"organization","name":"Omega Therapeutics, Inc.","symbol":"OMGA"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2024-02-09T16:57:49.000Z","date":"2024-02-07","kind":"grant","planned":false,"acquired":true,"shares":512848,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vested and became exercisable as to 14.28% of the underlying shares on February 7, 2024 and vests and will become exercisable in thirty-six (36) substantially equal monthly installments thereafter, such that the option shall be fully vested and exercisable on February 7, 2027, subject to the Reporting Person's continued service on the Issuer's Board of Directors through each such vesting date."}],"balance_after":512848,"derivative":{"exercise_price":3.59,"expiration_date":"2034-02-06","underlying":"Common Stock","underlying_shares":512848},"source":{"system":"sec-edgar","filing":"0000950170-24-013351","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1850838/000095017024013351/ownership.xml","form_type":"4"}},{"id":1830984,"issuer":{"id":83618,"kind":"organization","name":"Omega Therapeutics, Inc.","symbol":"OMGA"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2023-07-12T16:21:06.000Z","date":"2023-07-10","kind":"grant","planned":false,"acquired":true,"shares":36713,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests and becomes exercisable in thirty-six substantially equal monthly installments following the date of grant, such that the option shall be fully vested and exercisable on the third anniversary of the date of grant, subject to the Reporting Person's continued service on the Issuer's Board of Directors through each such vesting date."}],"balance_after":36713,"derivative":{"exercise_price":4.69,"expiration_date":"2023-07-09","underlying":"Common Stock","underlying_shares":36713},"source":{"system":"sec-edgar","filing":"0000950170-23-032670","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1850838/000095017023032670/ownership.xml","form_type":"4"}},{"id":1892330,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2023-05-16T20:18:58.000Z","date":"2023-05-12","kind":"grant","planned":false,"acquired":true,"shares":4486,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":54807,"source":{"system":"sec-edgar","filing":"0001209191-23-029792","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919123029792/doc4.xml","form_type":"4"}},{"id":2198925,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to Buy)","published_at":"2022-08-01T21:06:17.000Z","date":"2022-07-28","kind":"grant","acquired":true,"shares":47600,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option vests in full on July 28, 2023, subject to the reporting person's continued service on the Issuer's board of directors through and including the\napplicable vesting date and subject to acceleration under certain conditions."}],"balance_after":47600,"derivative":{"exercise_price":1.09,"expiration_date":"2032-07-28","underlying":"Common Stock","underlying_shares":47600},"source":{"system":"sec-edgar","filing":"0001104659-22-084772","document":"tm2222147-9_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":9,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000110465922084772/tm2222147-9_4seq1.xml","form_type":"4"}},{"id":2198924,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2022-08-01T21:06:17.000Z","date":"2022-07-28","kind":"grant","acquired":true,"shares":32400,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"These shares represent restricted stock units which were granted on July 28, 2022, and which will vest and be settled in common stock on July 28, 2023,\nsubject to the reporting person's continued service on the Issuer's board of directors through and including the applicable vesting date and subject to\nacceleration under certain conditions."}],"balance_after":259246,"source":{"system":"sec-edgar","filing":"0001104659-22-084772","document":"tm2222147-9_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000110465922084772/tm2222147-9_4seq1.xml","form_type":"4"}},{"id":2239997,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chairman & CEO"}}],"security":"Common Stock","published_at":"2022-06-07T21:05:17.000Z","date":"2022-06-03","kind":"tax_withholding","acquired":false,"shares":65770,"price":0.805,"value":52944.85,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents shares withheld to satisfy tax withholding obligations in connection with the vesting of 180,934 restricted stock units."}],"balance_after":226846,"source":{"system":"sec-edgar","filing":"0001104659-22-069015","document":"tm2217848-4_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000110465922069015/tm2217848-4_4seq1.xml","form_type":"4"}},{"id":2263338,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chairman & CEO"}}],"security":"Common Stock","published_at":"2022-05-19T20:30:41.000Z","date":"2022-05-18","kind":"purchase","acquired":true,"shares":37500,"price":0.6433,"value":24123.75,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were acquired in multiple transactions at prices ranging from $0.6245 to $0.6675, inclusive. The reporting person undertakes to provide Aprea Therapeutics, Inc., any security holder of Aprea Therapeutics, Inc., or staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in this footnote."}],"balance_after":292616,"source":{"system":"sec-edgar","filing":"0001104659-22-062916","document":"tm2216022-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000110465922062916/tm2216022-1_4seq1.xml","form_type":"4"}},{"id":2269008,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2022-05-17T20:44:22.000Z","date":"2022-05-13","kind":"grant","acquired":true,"shares":3456,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":50321,"source":{"system":"sec-edgar","filing":"0001209191-22-029707","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919122029707/doc4.xml","form_type":"4"}},{"id":2269007,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2022-05-17T20:44:22.000Z","date":"2022-05-13","kind":"grant","acquired":true,"shares":1265,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":46865,"source":{"system":"sec-edgar","filing":"0001209191-22-029707","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919122029707/doc4.xml","form_type":"4"}},{"id":2335118,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chairman & CEO"}}],"security":"Stock Option (right to Buy)","published_at":"2022-03-14T21:03:39.000Z","date":"2022-03-10","kind":"grant","acquired":true,"shares":427700,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"Twenty-five percent of these options vest on March 10, 2023, with the remaining options vesting ratably over the following 36 months, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions."}],"balance_after":427700,"derivative":{"exercise_price":1.82,"expiration_date":"2032-03-10","underlying":"Common Stock","underlying_shares":427700},"source":{"system":"sec-edgar","filing":"0001104659-22-033393","document":"tm229119-5_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":9,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000110465922033393/tm229119-5_4seq1.xml","form_type":"4"}},{"id":2335117,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chairman & CEO"}}],"security":"Common Stock","published_at":"2022-03-14T21:03:39.000Z","date":"2022-03-10","kind":"grant","acquired":true,"shares":100100,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"These shares represent restricted stock units which were granted on March 10, 2022, and which will vest and be settled in common stock as follows: (i) 33,366 shares on March 10, 2023, (ii) 33,367 shares on March 10, 2024 and (iii) 33,367 shares on March 10, 2025, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions."}],"balance_after":255116,"source":{"system":"sec-edgar","filing":"0001104659-22-033393","document":"tm229119-5_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000110465922033393/tm229119-5_4seq1.xml","form_type":"4"}},{"id":2364748,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chairman & CEO"}}],"security":"Common Stock","published_at":"2022-03-01T22:02:52.000Z","date":"2022-02-25","kind":"tax_withholding","acquired":false,"shares":21644,"price":1.74,"value":37660.56,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents shares withheld to satisfy tax withholding obligations in connection with the vesting of 55,166 restricted stock units."}],"balance_after":155016,"source":{"system":"sec-edgar","filing":"0001104659-22-028767","document":"tm227953-4_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000110465922028767/tm227953-4_4seq1.xml","form_type":"4"}},{"id":2711149,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2021-05-17T20:23:23.000Z","date":"2021-05-14","kind":"grant","acquired":true,"shares":2896,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":45600,"source":{"system":"sec-edgar","filing":"0001209191-21-033148","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919121033148/doc4.xml","form_type":"4"}},{"id":2711148,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2021-05-17T20:23:23.000Z","date":"2021-05-14","kind":"grant","acquired":true,"shares":530,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":42704,"source":{"system":"sec-edgar","filing":"0001209191-21-033148","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919121033148/doc4.xml","form_type":"4"}},{"id":2825780,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"officer_title":"Chairman & CEO"}}],"security":"Stock Option (right to Buy)","published_at":"2021-03-02T00:05:44.000Z","date":"2021-02-25","kind":"grant","acquired":true,"shares":329000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"Twenty-five percent of these options vest on February 25, 2022, with the remaining options vesting ratably over the following 36 months, subject to the reporting person's continued employment through and including the applicable vesting date and subject to acceleration under certain conditions."}],"balance_after":329000,"derivative":{"exercise_price":6,"expiration_date":"2031-02-25","underlying":"Common Stock","underlying_shares":329000},"source":{"system":"sec-edgar","filing":"0001140361-21-006730","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":10,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000114036121006730/form4.xml","form_type":"4"}},{"id":2825779,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"officer_title":"Chairman & CEO"}}],"security":"Common Stock","published_at":"2021-03-02T00:05:44.000Z","date":"2021-02-25","kind":"grant","acquired":true,"shares":88500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"These shares represent restricted stock units which were granted on February 25, 2021, and which will vest and be settled in common stock as follows: (i)  29,500 shares on August 25, 2021, (ii) 29,500 shares on February 25, 2022 and (iii) 29,500 shares on August 25, 2022, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions."}],"balance_after":176660,"source":{"system":"sec-edgar","filing":"0001140361-21-006730","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000114036121006730/form4.xml","form_type":"4"}},{"id":2825778,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"officer_title":"Chairman & CEO"}}],"security":"Common Stock","published_at":"2021-03-02T00:05:44.000Z","date":"2021-02-25","kind":"grant","acquired":true,"shares":77000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"These shares represent restricted stock units which were granted on February 25, 2021, and which will vest and be settled in common stock as follows: (i)  25,666 shares on February 25, 2022, (ii) 25,667 shares on February 25, 2023 and (iii) 25,667 shares on February 25, 2024, subject to the reporting person's continued employment through and including the applicable vesting dates and subject to acceleration under certain conditions."}],"balance_after":77160,"source":{"system":"sec-edgar","filing":"0001140361-21-006730","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000114036121006730/form4.xml","form_type":"4"}},{"id":3147860,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2020-05-15T20:07:19.000Z","date":"2020-05-13","kind":"grant","acquired":true,"shares":4218,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":42174,"source":{"system":"sec-edgar","filing":"0001209191-20-029710","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919120029710/doc4.xml","form_type":"4"}},{"id":3147859,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2020-05-15T20:07:19.000Z","date":"2020-05-13","kind":"grant","acquired":true,"shares":791,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":37956,"source":{"system":"sec-edgar","filing":"0001209191-20-029710","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919120029710/doc4.xml","form_type":"4"}},{"id":3194217,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Stock Option (right to Buy)","published_at":"2020-03-26T21:02:20.000Z","date":"2020-03-24","kind":"grant","acquired":true,"shares":127000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Twenty-five percent of these options vest on March 24, 2021, with the remaining options vesting ratably over the following 36 months, subject to the reporting person's continued employment through and including the applicable vesting date and subject to acceleration under certain conditions."}],"balance_after":127000,"derivative":{"exercise_price":35.5,"expiration_date":"2030-03-24","underlying":"Common Stock","underlying_shares":127000},"source":{"system":"sec-edgar","filing":"0001104659-20-038882","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000110465920038882/a4.xml","form_type":"4"}},{"id":3396579,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"Stock Option (right to Buy)","published_at":"2019-10-07T23:15:18.000Z","date":"2019-10-07","kind":"grant","acquired":true,"shares":306085,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"Twenty-five percent of these options vest on October 2, 2020, with the remaining options vesting ratably over the following 36 months, subject to the reporting person's continued employment through and including the applicable vesting date and subject to acceleration under certain conditions."}],"balance_after":306085,"derivative":{"exercise_price":15,"expiration_date":"2029-10-02","underlying":"Common Stock","underlying_shares":306085},"source":{"system":"sec-edgar","filing":"0001140361-19-018070","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":9,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000114036119018070/form4.xml","form_type":"4"}},{"id":3396578,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-10-07T23:15:18.000Z","date":"2019-10-07","kind":"purchase","acquired":true,"shares":5000,"price":15,"value":75000.0,"ownership":{"direct":false,"nature":"By spouse"},"balance_after":5000,"source":{"system":"sec-edgar","filing":"0001140361-19-018070","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000114036119018070/form4.xml","form_type":"4"}},{"id":3396577,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-10-07T23:15:18.000Z","date":"2019-10-07","kind":"purchase","acquired":true,"shares":1000,"price":15,"value":15000.0,"ownership":{"direct":false,"nature":"By adult child"},"footnotes":[{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."}],"balance_after":1000,"source":{"system":"sec-edgar","filing":"0001140361-19-018070","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000114036119018070/form4.xml","form_type":"4"}},{"id":3396576,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-10-07T23:15:18.000Z","date":"2019-10-07","kind":"purchase","acquired":true,"shares":1000,"price":15,"value":15000.0,"ownership":{"direct":false,"nature":"By adult child"},"footnotes":[{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."}],"balance_after":1000,"source":{"system":"sec-edgar","filing":"0001140361-19-018070","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000114036119018070/form4.xml","form_type":"4"}},{"id":3396575,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-10-07T23:15:18.000Z","date":"2019-10-07","kind":"purchase","acquired":true,"shares":1000,"price":15,"value":15000.0,"ownership":{"direct":false,"nature":"By adult child"},"footnotes":[{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."}],"balance_after":1000,"source":{"system":"sec-edgar","filing":"0001140361-19-018070","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000114036119018070/form4.xml","form_type":"4"}},{"id":3396574,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-10-07T23:15:18.000Z","date":"2019-10-07","kind":"purchase","acquired":true,"shares":1000,"price":15,"value":15000.0,"ownership":{"direct":false,"nature":"By adult child"},"footnotes":[{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."}],"balance_after":1000,"source":{"system":"sec-edgar","filing":"0001140361-19-018070","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000114036119018070/form4.xml","form_type":"4"}},{"id":3396573,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-10-07T23:15:18.000Z","date":"2019-10-07","kind":"purchase","acquired":true,"shares":1000,"price":15,"value":15000.0,"ownership":{"direct":false,"nature":"By adult child"},"footnotes":[{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."}],"balance_after":1000,"source":{"system":"sec-edgar","filing":"0001140361-19-018070","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000114036119018070/form4.xml","form_type":"4"}},{"id":3396572,"issuer":{"id":7948,"kind":"organization","name":"Aprea Therapeutics, Inc."},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-10-07T23:15:18.000Z","date":"2019-10-07","kind":"purchase","acquired":true,"shares":1000,"price":15,"value":15000.0,"ownership":{"direct":false,"nature":"By adult child"},"footnotes":[{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The reporting person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the reporting person is the beneficial owner of such securities for purposes of Section 16 of the Securities Exchange Act of 1934, or for any other purpose."}],"balance_after":1000,"source":{"system":"sec-edgar","filing":"0001140361-19-018070","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1214496/000114036119018070/form4.xml","form_type":"4"}},{"id":3519276,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2019-05-20T20:44:46.000Z","date":"2019-05-16","kind":"grant","acquired":true,"shares":747,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":37165,"source":{"system":"sec-edgar","filing":"0001209191-19-031429","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919119031429/doc4.xml","form_type":"4"}},{"id":3519275,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2019-05-20T20:44:46.000Z","date":"2019-05-16","kind":"grant","acquired":true,"shares":3785,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":36418,"source":{"system":"sec-edgar","filing":"0001209191-19-031429","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919119031429/doc4.xml","form_type":"4"}},{"id":3528398,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Non-Qualified Stock Option (right to buy)","published_at":"2019-05-14T20:19:12.000Z","date":"2019-05-10","kind":"exercise","acquired":false,"shares":15658,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F2","text":"This option was previously reported as covering 7,500 shares at an exercise price of $50.78 per share, but was adjusted pursuant to the anti-dilution provisions of the award in connection with the spin-off of\nSeaSpine Holdings Corporation on July 1, 2015 to 7,829 shares of common stock at an exercise price of $43.93 per share."},{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F3","text":"In accordance with the terms of the stock option plan, the exercise price of the option and number of shares subject to the option have been adjusted to reflect the two-for-one stock split that occurred on December 21, 2016."},{"field":"shares","element":"transactionShares","label":"F2","text":"This option was previously reported as covering 7,500 shares at an exercise price of $50.78 per share, but was adjusted pursuant to the anti-dilution provisions of the award in connection with the spin-off of\nSeaSpine Holdings Corporation on July 1, 2015 to 7,829 shares of common stock at an exercise price of $43.93 per share."},{"field":"shares","element":"transactionShares","label":"F3","text":"In accordance with the terms of the stock option plan, the exercise price of the option and number of shares subject to the option have been adjusted to reflect the two-for-one stock split that occurred on December 21, 2016."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"25% of the stock options vested every quarter from the grant date of 5/19/2011"}],"balance_after":0,"derivative":{"exercise_price":21.965,"expiration_date":"2019-05-17","underlying":"Common Stock","underlying_shares":15658},"source":{"system":"sec-edgar","filing":"0001209191-19-029618","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919119029618/doc4.xml","form_type":"4"}},{"id":3528397,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2019-05-14T20:19:12.000Z","date":"2019-05-10","kind":"sale","acquired":false,"shares":15658,"price":51.5601,"value":807328.0458,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price shown above represents the weighted average price of the shares sold. The range of sale prices was $51.50 to $52.50."}],"balance_after":32633,"source":{"system":"sec-edgar","filing":"0001209191-19-029618","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919119029618/doc4.xml","form_type":"4"}},{"id":3528396,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2019-05-14T20:19:12.000Z","date":"2019-05-10","kind":"exercise","acquired":true,"shares":15658,"price":21.965,"value":343927.97,"ownership":{"direct":true},"balance_after":48291,"source":{"system":"sec-edgar","filing":"0001209191-19-029618","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919119029618/doc4.xml","form_type":"4"}},{"id":3924699,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2018-05-21T20:52:20.000Z","date":"2018-05-17","kind":"grant","acquired":true,"shares":2965,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":32633,"source":{"system":"sec-edgar","filing":"0001209191-18-031920","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919118031920/doc4.xml","form_type":"4"}},{"id":4012448,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Non-Qualified Stock Option (right to buy)","published_at":"2018-03-06T21:17:45.000Z","date":"2018-03-05","kind":"exercise","acquired":false,"shares":15658,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"25% of the stock options vest every quarter from the grant date of 5/19/2010"},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"This option was previously reported as covering 7,500 shares at an exercise price of $41.75 per share, but was adjusted pursuant to the anti-dilution provisions of the award in connection with the spin-off of SeaSpine Holdings Corporation on July 1, 2015 to 7,829 shares of common stock at an exercise price of $36.12 per share."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"In accordance with the terms of the stock option plan, the exercise price of the option and number of shares subject to the option have been adjusted to reflect the two-for-one stock split that occurred on December 21, 2016."}],"balance_after":0,"derivative":{"exercise_price":18.06,"expiration_date":"2018-05-19","underlying":"Common Stock","underlying_shares":15658},"source":{"system":"sec-edgar","filing":"0001209191-18-017221","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919118017221/doc4.xml","form_type":"4"}},{"id":4012447,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2018-03-06T21:17:45.000Z","date":"2018-03-05","kind":"sale","acquired":false,"shares":15658,"price":52.8795,"value":827987.211,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price shown above represents the weighted average price of the shares sold. The range of sale prices was $52.73 to $53.04."}],"balance_after":29668,"source":{"system":"sec-edgar","filing":"0001209191-18-017221","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919118017221/doc4.xml","form_type":"4"}},{"id":4012446,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2018-03-06T21:17:45.000Z","date":"2018-03-05","kind":"exercise","acquired":true,"shares":15658,"price":18.06,"value":282783.48,"ownership":{"direct":true},"balance_after":45326,"source":{"system":"sec-edgar","filing":"0001209191-18-017221","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919118017221/doc4.xml","form_type":"4"}},{"id":4305406,"issuer":{"id":2707,"kind":"organization","name":"INTEGRA LIFESCIENCES HOLDINGS CORP","symbol":"IART"},"owners":[{"id":48465,"kind":"person","name":"SCHADE CHRISTIAN S","position":1,"cik":"0001214496","reported_name":"SCHADE CHRISTIAN S","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2017-05-25T20:37:34.000Z","date":"2017-05-23","kind":"grant","acquired":true,"shares":3544,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"On December 21, 2016, the common stock of Integra LifeSciences Holdings Corporation split two-for-one, resulting in the reporting person's ownership of one additional share of common stock for each share of common stock owned as of that date, as reflected in the totals listed on this Form 4."}],"balance_after":29668,"source":{"system":"sec-edgar","filing":"0001209191-17-035423","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/917520/000120919117035423/doc4.xml","form_type":"4"}}]}