{"transactions":[{"id":772113,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2026-05-20T01:45:41.000Z","date":"2026-05-14","kind":"grant","planned":false,"acquired":true,"shares":127,"price":167.943,"value":21328.761,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These shares were acquired under the Praxis Precision Medicines, Inc. Employee Stock Purchase Plan in transactions that were exempt under both Rule 16b-3(d) and Rule 16b-3(c)."}],"balance_after":13572.656,"source":{"system":"sec-edgar","filing":"0001827639-26-000007","document":"wk-form4_1779241539.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000182763926000007/wk-form4_1779241539.xml","form_type":"4"}},{"id":940072,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2026-01-14T01:20:33.000Z","date":"2026-01-12","kind":"tax_withholding","planned":false,"acquired":false,"shares":344,"price":275.74,"value":94854.56,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units."}],"balance_after":13445.656,"source":{"system":"sec-edgar","filing":"0001827639-26-000005","document":"wk-form4_1768353630.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000182763926000005/wk-form4_1768353630.xml","form_type":"4"}},{"id":941020,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2026-01-12T22:51:02.000Z","date":"2026-01-08","kind":"grant","planned":false,"acquired":true,"shares":7500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The shares underlying this stock option vest over a four-year period, with 25% vesting on January 8, 2027 and the remaining 75% vesting in 36 equal monthly installments thereafter, subject to the reporting person's continued service through each vesting date."}],"balance_after":7500,"derivative":{"exercise_price":294.38,"expiration_date":"2036-01-08","underlying":"Common Stock","underlying_shares":7500},"source":{"system":"sec-edgar","filing":"0001689548-26-000014","document":"wk-form4_1768258260.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954826000014/wk-form4_1768258260.xml","form_type":"4"}},{"id":941019,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2026-01-12T22:51:02.000Z","date":"2026-01-10","kind":"tax_withholding","planned":false,"acquired":false,"shares":367,"price":288.45,"value":105861.15,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F2","text":"Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units."}],"balance_after":13789.656,"source":{"system":"sec-edgar","filing":"0001689548-26-000014","document":"wk-form4_1768258260.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954826000014/wk-form4_1768258260.xml","form_type":"4"}},{"id":941018,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2026-01-12T22:51:02.000Z","date":"2026-01-08","kind":"grant","planned":false,"acquired":true,"shares":3750,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Ms. Mastrocola was awarded 3,750 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock. The restricted stock units vest in equal annual installments over a four-year period beginning on the one-year anniversary of the vesting commencement date of January 8, 2026. The restricted stock units may be settled only by delivering shares of the Issuer's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance."}],"balance_after":14156.656,"source":{"system":"sec-edgar","filing":"0001689548-26-000014","document":"wk-form4_1768258260.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954826000014/wk-form4_1768258260.xml","form_type":"4"}},{"id":942138,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2026-01-09T21:47:53.000Z","date":"2026-01-07","kind":"tax_withholding","planned":false,"acquired":false,"shares":35,"price":292.63,"value":10242.05,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units."}],"balance_after":10406.656,"source":{"system":"sec-edgar","filing":"0001827639-26-000002","document":"wk-form4_1767995270.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000182763926000002/wk-form4_1767995270.xml","form_type":"4"}},{"id":991382,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":false,"shares":5250,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F8","text":"The shares underlying this stock option vested as to 7/48ths on July 29, 2024 and the remaining shares vest in substantially equal monthly installments over the following 41 months, subject to the Reporting Person's continued service through each vesting date."}],"balance_after":11376,"derivative":{"exercise_price":56.94,"expiration_date":"2034-07-29","underlying":"Common Stock","underlying_shares":5250},"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":16,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991381,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":false,"shares":2351,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F7","text":"The shares underlying this stock option vested as to 25% on January 12, 2024 and the remaining shares vest in substantially equal monthly installments over the following 36 months, subject to the Reporting Person's continued service through each vesting date."}],"balance_after":981,"derivative":{"exercise_price":44.4,"expiration_date":"2033-01-12","underlying":"Common Stock","underlying_shares":2351},"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":15,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991380,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":false,"shares":207,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":0,"derivative":{"exercise_price":44.4,"exercise_date":"2023-01-12","expiration_date":"2033-01-12","underlying":"Common Stock","underlying_shares":207},"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":14,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991379,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":false,"shares":2680,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The shares underlying this stock option vested as to 50% on January 12, 2024 and the remaining 50% vesting over a four-year period, with 25% of such shares vesting on January 12, 2025 and the remaining vesting in substantially equal monthly installments over the following 36 months, subject to the Reporting Person's continued service through each vesting date."}],"balance_after":9320,"derivative":{"exercise_price":43.37,"expiration_date":"2034-01-12","underlying":"Common Stock","underlying_shares":2680},"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":13,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991378,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":false,"shares":1557,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"This option was fully vested as of September 8, 2024."}],"balance_after":0,"derivative":{"exercise_price":133.65,"expiration_date":"2030-09-13","underlying":"Common Stock","underlying_shares":1557},"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":12,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991377,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":false,"shares":508,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"This option was fully vested as of May 28, 2024."}],"balance_after":0,"derivative":{"exercise_price":83.85,"expiration_date":"2030-06-04","underlying":"Common Stock","underlying_shares":508},"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":11,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991376,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":false,"shares":1047,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"This option was fully vested as of January 1, 2023."}],"balance_after":0,"derivative":{"exercise_price":49.5,"expiration_date":"2029-09-23","underlying":"Common Stock","underlying_shares":1047},"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":10,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991375,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"sale","planned":false,"acquired":false,"shares":2145,"price":192.711,"value":413365.095,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported is a weighted average price. The securities were sold in multiple transactions at per share prices ranging from $192.552 to $193.109. The Reporting Person undertakes to provide upon request from the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote."}],"balance_after":10441.656,"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":9,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991374,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"sale","planned":false,"acquired":false,"shares":11455,"price":191.958,"value":2198878.89,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported is a weighted average price. The securities were sold in multiple transactions at per share prices ranging from $191.500 to $192.432. The Reporting Person undertakes to provide upon request from the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote."}],"balance_after":12586.656,"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991373,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":true,"shares":5250,"price":56.94,"value":298935.0,"ownership":{"direct":true},"balance_after":24041.656,"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991372,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":true,"shares":2351,"price":44.4,"value":104384.4,"ownership":{"direct":true},"balance_after":18791.656,"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991371,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":true,"shares":207,"price":44.4,"value":9190.8,"ownership":{"direct":true},"balance_after":16440.656,"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991370,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":true,"shares":2680,"price":43.37,"value":116231.6,"ownership":{"direct":true},"balance_after":16233.656,"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991369,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":true,"shares":1557,"price":133.65,"value":208093.05,"ownership":{"direct":true},"balance_after":13553.656,"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991368,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":true,"shares":508,"price":83.85,"value":42595.8,"ownership":{"direct":true},"balance_after":11996.656,"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":991367,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-11-22T02:39:47.000Z","date":"2025-11-20","kind":"exercise","planned":false,"acquired":true,"shares":1047,"price":49.5,"value":51826.5,"ownership":{"direct":true},"balance_after":11488.656,"source":{"system":"sec-edgar","filing":"0001104659-25-115098","document":"tm2531977-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465925115098/tm2531977-1_4seq1.xml","form_type":"4"}},{"id":1267332,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-02-14T21:29:37.000Z","date":"2025-02-12","kind":"tax_withholding","planned":false,"acquired":false,"shares":40,"price":85.4,"value":3416.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units."}],"balance_after":10441.656,"source":{"system":"sec-edgar","filing":"0001689548-25-000026","document":"wk-form4_1739568570.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954825000026/wk-form4_1739568570.xml","form_type":"4"}},{"id":1303479,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-01-14T23:51:07.000Z","date":"2025-01-10","kind":"grant","planned":false,"acquired":true,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The shares underlying this stock option vest over a four-year period, with 25% vesting on January 10, 2026 and the remaining 75% vesting in 36 equal monthly installments thereafter, subject to the reporting person's continued service through each vesting date."}],"balance_after":10000,"derivative":{"exercise_price":63.15,"expiration_date":"2035-01-10","underlying":"Common Stock","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001689548-25-000016","document":"wk-form4_1736898659.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954825000016/wk-form4_1736898659.xml","form_type":"4"}},{"id":1303478,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-01-14T23:51:07.000Z","date":"2025-01-12","kind":"tax_withholding","planned":false,"acquired":false,"shares":390,"price":63.15,"value":24628.5,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F2","text":"Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported restricted stock units."}],"balance_after":10481.656,"source":{"system":"sec-edgar","filing":"0001689548-25-000016","document":"wk-form4_1736898659.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954825000016/wk-form4_1736898659.xml","form_type":"4"}},{"id":1303477,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-01-14T23:51:07.000Z","date":"2025-01-10","kind":"grant","planned":false,"acquired":true,"shares":5000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Ms. Mastrocola was awarded 5,000 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock. The restricted stock units vest in equal annual installments over a four-year period beginning on the one-year anniversary of the vesting commencement date of January 10, 2025. The restricted stock units may be settled only by delivering shares of the Issuer's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance."}],"balance_after":10871.656,"source":{"system":"sec-edgar","filing":"0001689548-25-000016","document":"wk-form4_1736898659.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954825000016/wk-form4_1736898659.xml","form_type":"4"}},{"id":1306716,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2025-01-09T00:50:24.000Z","date":"2025-01-07","kind":"tax_withholding","planned":false,"acquired":false,"shares":35,"price":77.52,"value":2713.2,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported Restricted Share Units."}],"balance_after":5871.656,"source":{"system":"sec-edgar","filing":"0001689548-25-000007","document":"wk-form4_1736383818.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954825000007/wk-form4_1736383818.xml","form_type":"4"}},{"id":1359202,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2024-11-20T02:50:17.000Z","date":"2024-11-14","kind":"grant","planned":false,"acquired":true,"shares":294,"price":37.4,"value":10995.6,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These shares were acquired under the Praxis Precision Medicines, Inc. Employee Stock Purchase Plan in transactions that were exempt under both Rule 16b-3(d) and Rule 16b-3(c)."}],"balance_after":5906.656,"source":{"system":"sec-edgar","filing":"0001104659-24-120748","document":"tm2428929-2_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465924120748/tm2428929-2_4seq1.xml","form_type":"4"}},{"id":1363761,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2024-11-16T02:30:13.000Z","date":"2024-11-14","kind":"exercise","planned":false,"acquired":false,"shares":4374,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares underlying this stock option vested as to 7/48ths on July 29, 2024 and the remaining shares vest in substantially equal monthly installments over the following 41 months, subject to the reporting person's continued service through each vesting date."}],"balance_after":16626,"derivative":{"exercise_price":56.94,"expiration_date":"2034-07-29","underlying":"Common Stock","underlying_shares":4374},"source":{"system":"sec-edgar","filing":"0001104659-24-119843","document":"tm2428636-1_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465924119843/tm2428636-1_4seq1.xml","form_type":"4"}},{"id":1363760,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2024-11-16T02:30:13.000Z","date":"2024-11-14","kind":"sale","planned":false,"acquired":false,"shares":5188.344,"price":81.783,"value":424318.337352,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported is a weighted average price. The securities were sold in multiple transactions at per share prices ranging from $81.23 to $81.797. The Reporting Person undertakes to provide upon request from the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote."}],"balance_after":5612.656,"source":{"system":"sec-edgar","filing":"0001104659-24-119843","document":"tm2428636-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465924119843/tm2428636-1_4seq1.xml","form_type":"4"}},{"id":1363759,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2024-11-16T02:30:13.000Z","date":"2024-11-14","kind":"exercise","planned":false,"acquired":true,"shares":4374,"price":56.94,"value":249055.56,"ownership":{"direct":true},"balance_after":10801,"source":{"system":"sec-edgar","filing":"0001104659-24-119843","document":"tm2428636-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465924119843/tm2428636-1_4seq1.xml","form_type":"4"}},{"id":1445301,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2024-08-01T01:01:10.000Z","date":"2024-07-29","kind":"grant","planned":false,"acquired":true,"shares":21000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares underlying this stock option vested as to 7/48ths on July 29, 2024 and the remaining shares vest in substantially equal monthly installments over the following 41 months, subject to the reporting person's continued service through each vesting date."}],"balance_after":21000,"derivative":{"exercise_price":56.94,"expiration_date":"2034-07-29","underlying":"Common Stock","underlying_shares":21000},"source":{"system":"sec-edgar","filing":"0001104659-24-084504","document":"tm2420554-2_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465924084504/tm2420554-2_4seq1.xml","form_type":"4"}},{"id":1445300,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2024-08-01T01:01:10.000Z","date":"2024-07-29","kind":"grant","planned":false,"acquired":true,"shares":4500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Ms. Mastrocola was awarded 4,500 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock. The restricted stock units vest in equal annual installments over a four-year period beginning on January 12, 2025, subject to the reporting person's continued service through each vesting date. The restricted stock units have no expiration date."}],"balance_after":6427,"source":{"system":"sec-edgar","filing":"0001104659-24-084504","document":"tm2420554-2_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465924084504/tm2420554-2_4seq1.xml","form_type":"4"}},{"id":1643192,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2024-02-14T21:14:23.000Z","date":"2024-02-12","kind":"tax_withholding","planned":false,"acquired":false,"shares":48,"price":44.65,"value":2143.2,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported Restricted Share Units."}],"balance_after":1927,"source":{"system":"sec-edgar","filing":"0001689548-24-000027","document":"wk-form4_1707945236.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954824000027/wk-form4_1707945236.xml","form_type":"4"}},{"id":1677908,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2024-01-17T21:47:09.000Z","date":"2024-01-12","kind":"grant","planned":false,"acquired":true,"shares":12000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares underlying this stock option vest as follows: 50% vested in full on January 12, 2024 (the \"Grant Date\") and the remaining 50% vesting over a four-year period, with 25% of such shares vesting on the first anniversary of the Grant Date and the remaining shares vesting in 36 equal monthly installments thereafter, subject to the reporting person's continued service through each vesting date."}],"balance_after":12000,"derivative":{"exercise_price":43.37,"expiration_date":"2034-01-12","underlying":"Common Stock","underlying_shares":12000},"source":{"system":"sec-edgar","filing":"0001689548-24-000018","document":"wk-form4_1705528014.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954824000018/wk-form4_1705528014.xml","form_type":"4"}},{"id":1682730,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2024-01-10T02:08:04.000Z","date":"2024-01-07","kind":"tax_withholding","planned":false,"acquired":false,"shares":35,"price":25.19,"value":881.65,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported Restricted Share Units."}],"balance_after":1975,"source":{"system":"sec-edgar","filing":"0001689548-24-000005","document":"wk-form4_1704852471.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954824000005/wk-form4_1704852471.xml","form_type":"4"}},{"id":2020006,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2023-02-14T01:43:46.000Z","date":"2023-02-12","kind":"tax_withholding","acquired":false,"shares":711,"price":3.94,"value":2801.34,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported Restricted Share Units."}],"balance_after":30160,"source":{"system":"sec-edgar","filing":"0001689548-23-000048","document":"wf-form4_167633900969675.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954823000048/wf-form4_167633900969675.xml","form_type":"4"}},{"id":2053774,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2023-01-18T00:30:32.000Z","date":"2023-01-12","kind":"grant","acquired":true,"shares":50000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares underlying this stock option vest over a four-year period, with 25% vesting on January 12, 2024 and the remaining 75% vesting in 36 equal monthly installments thereafter, subject to the reporting person's continued service through each vesting date."}],"balance_after":50000,"derivative":{"exercise_price":2.96,"expiration_date":"2033-01-12","underlying":"Common Stock","underlying_shares":50000},"source":{"system":"sec-edgar","filing":"0001689548-23-000024","document":"wf-form4_167400181408222.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954823000024/wf-form4_167400181408222.xml","form_type":"4"}},{"id":2054787,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2023-01-13T12:43:10.000Z","date":"2023-01-12","kind":"grant","acquired":true,"shares":3110,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Ms. Mastrocola opted to receive this option grant in lieu of a cash bonus for the fiscal year ended December 31, 2022."}],"balance_after":3110,"derivative":{"exercise_price":2.96,"exercise_date":"2023-01-12","expiration_date":"2033-01-12","underlying":"Common Stock","underlying_shares":3110},"source":{"system":"sec-edgar","filing":"0001689548-23-000015","document":"wf-form4_167361377763317.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954823000015/wf-form4_167361377763317.xml","form_type":"4"}},{"id":2058887,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2023-01-09T23:16:26.000Z","date":"2023-01-07","kind":"tax_withholding","acquired":false,"shares":520,"price":2.52,"value":1310.4,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported Restricted Share Units."}],"balance_after":30871,"source":{"system":"sec-edgar","filing":"0001689548-23-000006","document":"wf-form4_167330616920258.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954823000006/wf-form4_167330616920258.xml","form_type":"4"}},{"id":2222085,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2022-06-24T20:52:28.000Z","date":"2022-06-22","kind":"grant","acquired":true,"shares":16000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares underlying this stock option vest over a four-year period, with 25% vesting on June 22, 2023 and the remaining 75% vesting in 36 equal monthly installments thereafter, subject to the reporting person's continued service through each vesting date."}],"balance_after":16000,"derivative":{"exercise_price":2.12,"expiration_date":"2032-06-22","underlying":"Common Stock","underlying_shares":16000},"source":{"system":"sec-edgar","filing":"0001689548-22-000094","document":"wf-form4_165610393075032.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954822000094/wf-form4_165610393075032.xml","form_type":"4"}},{"id":2225453,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2022-06-21T20:35:45.000Z","date":"2022-06-16","kind":"purchase","acquired":true,"shares":3000,"price":1.925,"value":5775.0,"ownership":{"direct":true},"balance_after":31391,"source":{"system":"sec-edgar","filing":"0001689548-22-000082","document":"wf-form4_165584373130613.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954822000082/wf-form4_165584373130613.xml","form_type":"4"}},{"id":2265746,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2022-05-18T21:46:51.000Z","date":"2022-05-13","kind":"grant","acquired":true,"shares":2557,"price":8.798,"value":22496.486,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These shares were acquired under the Praxis Precision Medicines, Inc. Employee Stock Purchase Plan in transactions that were exempt under both Rule 16b-3(d) and Rule 16b-3(c)."}],"balance_after":28391,"source":{"system":"sec-edgar","filing":"0001689548-22-000046","document":"wf-form4_165291013839730.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954822000046/wf-form4_165291013839730.xml","form_type":"4"}},{"id":2394564,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2022-02-16T00:35:44.000Z","date":"2022-02-12","kind":"tax_withholding","acquired":false,"shares":584,"price":12.85,"value":7504.4,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Shares withheld by the Issuer to satisfy the tax withholding obligations in connection with the vesting of certain previously reported Restricted Share Units."}],"balance_after":25834,"source":{"system":"sec-edgar","filing":"0001689548-22-000005","document":"wf-form4_164497172165661.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954822000005/wf-form4_164497172165661.xml","form_type":"4"}},{"id":2437774,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2022-01-11T21:07:41.000Z","date":"2022-01-07","kind":"grant","acquired":true,"shares":21000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares underlying this stock option vest over a four-year period, with 25% vesting on January 7, 2023 and the remaining 75% vesting in 36 equal monthly installments thereafter, subject to the reporting person's continued service through each vesting date."}],"balance_after":21000,"derivative":{"exercise_price":18.11,"expiration_date":"2032-01-07","underlying":"Common Stock","underlying_shares":21000},"source":{"system":"sec-edgar","filing":"0001104659-22-003158","document":"tm222494-2_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465922003158/tm222494-2_4seq1.xml","form_type":"4"}},{"id":2437773,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2022-01-11T21:07:41.000Z","date":"2022-01-07","kind":"grant","acquired":true,"shares":6000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Ms. Mastrocola was awarded 6,000 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock. The restricted stock units vest in equal annual installments over a four-year period beginning on January 7, 2023, subject to the reporting person's continued service through each vesting date. The restricted stock units may be settled only by delivering shares of the Issuer's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance."}],"balance_after":26418,"source":{"system":"sec-edgar","filing":"0001104659-22-003158","document":"tm222494-2_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000110465922003158/tm222494-2_4seq1.xml","form_type":"4"}},{"id":2854893,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2021-02-17T21:56:43.000Z","date":"2021-02-12","kind":"grant","acquired":true,"shares":48700,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares underlying this stock option vest over a four-year period, with 27,175 shares vesting on the one-year anniversary of the vesting commencement date of February 12, 2021 and the remaining 21,525 shares vesting in 36 equal monthly installments following such first anniversary, subject to the reporting person's continued service through each vesting date."}],"balance_after":48700,"derivative":{"exercise_price":52.53,"expiration_date":"2031-02-12","underlying":"Common Stock","underlying_shares":48700},"source":{"system":"sec-edgar","filing":"0001689548-21-000011","document":"wf-form4_161359894605862.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954821000011/wf-form4_161359894605862.xml","form_type":"4"}},{"id":2854892,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2021-02-17T21:56:43.000Z","date":"2021-02-12","kind":"grant","acquired":true,"shares":8200,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Ms. Mastrocola was awarded 8,200 restricted stock units. Each restricted stock unit represents a contingent right to receive one share of the Issuer's Common Stock. The restricted stock units vest in equal annual installments over a four-year period beginning on the one-year anniversary of the vesting commencement date of February 12, 2021. The restricted stock units may be settled only by delivering shares of the Issuer's Common Stock, and thus, the grant is being reported in Table 1 as allowed per SEC guidance."}],"balance_after":20418,"source":{"system":"sec-edgar","filing":"0001689548-21-000011","document":"wf-form4_161359894605862.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000168954821000011/wf-form4_161359894605862.xml","form_type":"4"}},{"id":2992876,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2020-11-04T22:32:49.000Z","date":"2020-11-02","kind":"exercise","acquired":false,"shares":12218,"price":3.3,"value":40319.4,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"25% of this option vested and became exercisable on January 1, 2020, with the remainder vesting in 36 equal monthly installments thereafter. This option was initially for 27,928 shares and the Reporting Person has exercised her option to purchase 12,218 shares."}],"balance_after":15710,"derivative":{"exercise_price":3.3,"expiration_date":"2029-09-23","underlying":"Common Stock","underlying_shares":12218},"source":{"system":"sec-edgar","filing":"0000899243-20-030396","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000089924320030396/doc4.xml","form_type":"4"}},{"id":2992875,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":45990,"kind":"person","name":"Mastrocola Lauren","position":1,"cik":"0001827639","reported_name":"Mastrocola Lauren","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Principal Accounting Officer"}}],"security":"Common Stock","published_at":"2020-11-04T22:32:49.000Z","date":"2020-11-02","kind":"exercise","acquired":true,"shares":12218,"price":3.3,"value":40319.4,"ownership":{"direct":true},"balance_after":12218,"source":{"system":"sec-edgar","filing":"0000899243-20-030396","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000089924320030396/doc4.xml","form_type":"4"}}]}