{"transactions":[{"id":765988,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2026-05-22T20:30:03.000Z","date":"2026-05-21","kind":"grant","planned":false,"acquired":true,"shares":6090,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares of common stock underlying this stock option award will vest in full on the date that is the earlier of (i) the first anniversary of the grant date or (ii) the Issuer's 2027 Annual Meeting of Stockholders, subject to the Reporting Person's continued service to the Issuer through the vesting date."}],"balance_after":6090,"derivative":{"exercise_price":89.63,"expiration_date":"2036-05-21","underlying":"Common Stock","underlying_shares":6090},"source":{"system":"sec-edgar","filing":"0001692444-26-000010","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000169244426000010/ownership.xml","form_type":"4"}},{"id":784778,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2026-05-11T21:00:13.000Z","date":"2026-05-08","kind":"exercise","planned":true,"acquired":false,"shares":599,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transaction was effected pursuant to a Rule 10b5-1 trading plan adopted on December 23, 2025."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares of common stock underlying this stock option award vested as to 25% of the shares on April 6, 2023, with the remaining three quarters vesting in equal monthly installments over the following three years, subject to the Reporting Person's continued service to the Issuer on each such vesting date."}],"balance_after":0,"derivative":{"exercise_price":8.44,"expiration_date":"2032-06-06","underlying":"Common Stock","underlying_shares":599},"source":{"system":"sec-edgar","filing":"0001692444-26-000008","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000169244426000008/ownership.xml","form_type":"4"}},{"id":784777,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-05-11T21:00:13.000Z","date":"2026-05-08","kind":"sale","planned":true,"acquired":false,"shares":599,"price":85.47,"value":51196.53,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transaction was effected pursuant to a Rule 10b5-1 trading plan adopted on December 23, 2025."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001692444-26-000008","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000169244426000008/ownership.xml","form_type":"4"}},{"id":784776,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-05-11T21:00:13.000Z","date":"2026-05-08","kind":"exercise","planned":true,"acquired":true,"shares":599,"price":8.44,"value":5055.56,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transaction was effected pursuant to a Rule 10b5-1 trading plan adopted on December 23, 2025."}],"balance_after":599,"source":{"system":"sec-edgar","filing":"0001692444-26-000008","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000169244426000008/ownership.xml","form_type":"4"}},{"id":822885,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2026-04-01T21:26:04.000Z","date":"2026-03-31","kind":"exercise","planned":true,"acquired":false,"shares":599,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 23, 2025."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares of common stock underlying this stock option award vested as to 25% of the shares on April 6, 2023, with the remaining three quarters vesting in equal monthly installments over the following three years, subject to the Reporting Person's continued service to the Issuer on each such vesting date."}],"balance_after":599,"derivative":{"exercise_price":8.44,"expiration_date":"2032-06-06","underlying":"Common Stock","underlying_shares":599},"source":{"system":"sec-edgar","filing":"0001692444-26-000006","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000169244426000006/ownership.xml","form_type":"4"}},{"id":822884,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-04-01T21:26:04.000Z","date":"2026-03-31","kind":"sale","planned":true,"acquired":false,"shares":599,"price":80.11,"value":47985.89,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 23, 2025."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001692444-26-000006","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000169244426000006/ownership.xml","form_type":"4"}},{"id":822883,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-04-01T21:26:04.000Z","date":"2026-03-31","kind":"exercise","planned":true,"acquired":true,"shares":599,"price":8.44,"value":5055.56,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 23, 2025."}],"balance_after":599,"source":{"system":"sec-edgar","filing":"0001692444-26-000006","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000169244426000006/ownership.xml","form_type":"4"}},{"id":827382,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2026-03-26T22:00:05.000Z","date":"2026-03-24","kind":"exercise","planned":true,"acquired":false,"shares":27594,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 23, 2025."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares of common stock underlying this stock option award vested as to 25% of the shares on April 6, 2023, with the remaining three quarters vesting in equal monthly installments over the following three years, subject to the Reporting Person's continued service to the Issuer on each such vesting date."}],"balance_after":1198,"derivative":{"exercise_price":8.44,"expiration_date":"2032-06-06","underlying":"Common Stock","underlying_shares":27594},"source":{"system":"sec-edgar","filing":"0001692444-26-000003","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000169244426000003/ownership.xml","form_type":"4"}},{"id":827381,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-03-26T22:00:05.000Z","date":"2026-03-24","kind":"sale","planned":true,"acquired":false,"shares":27594,"price":78.05,"value":2153711.7,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 23, 2025."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001692444-26-000003","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000169244426000003/ownership.xml","form_type":"4"}},{"id":827380,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-03-26T22:00:05.000Z","date":"2026-03-24","kind":"exercise","planned":true,"acquired":true,"shares":27594,"price":8.44,"value":232893.36,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transaction was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on December 23, 2025."}],"balance_after":27594,"source":{"system":"sec-edgar","filing":"0001692444-26-000003","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000169244426000003/ownership.xml","form_type":"4"}},{"id":1137212,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-05-22T20:43:34.000Z","date":"2025-05-22","kind":"grant","planned":false,"acquired":true,"shares":12500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares of common stock underlying this stock option award will vest in full on the date that is the earlier of (i) the first anniversary of the grant date or (ii) the Issuer's 2026 Annual Meeting of Stockholders, subject to the Reporting Person's continued service to the Issuer through the vesting date."}],"balance_after":12500,"derivative":{"exercise_price":18.36,"expiration_date":"2035-05-22","underlying":"Common Stock","underlying_shares":12500},"source":{"system":"sec-edgar","filing":"0000950170-25-076410","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000095017025076410/ownership.xml","form_type":"4"}},{"id":1147442,"issuer":{"id":6838,"kind":"organization","name":"Rallybio Corp","symbol":"RLYB"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Option (Right to Buy)","published_at":"2025-05-15T21:05:24.000Z","date":"2025-05-13","kind":"grant","planned":false,"acquired":true,"shares":28500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option was granted under the Company's 2021 Equity Incentive Plan. The option vests on the earlier of May 13, 2026 or the date of the Company's 2026 Annual Meeting of Stockholders."}],"balance_after":28500,"derivative":{"exercise_price":0.3,"expiration_date":"2035-05-13","underlying":"Common Stock","underlying_shares":28500},"source":{"system":"sec-edgar","filing":"0001739410-25-000082","document":"wk-form4_1747343116.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1739410/000173941025000082/wk-form4_1747343116.xml","form_type":"4"}},{"id":1477336,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2024-06-17T23:24:37.000Z","date":"2024-06-13","kind":"sale","planned":false,"acquired":false,"shares":2220,"price":5.14,"value":11410.8,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person."},{"field":"shares","element":"transactionShares","label":"F1","text":"The shares were sold upon the vesting of restricted share units solely to cover estimated withholding taxes, pursuant to automatic sale instructions included in the relevant Restricted Share Unit Agreement. The sale was not a discretionary trade by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $5.13 to $5.15. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":20203,"source":{"system":"sec-edgar","filing":"0000904454-24-000369","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445424000369/edgar.xml","form_type":"4"}},{"id":1500456,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2024-05-28T23:59:06.000Z","date":"2024-05-23","kind":"grant","planned":false,"acquired":true,"shares":11000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares of common stock underlying this stock option award will vest in full on the date that is the earlier of (i) the first anniversary of the grant date or (ii) the Issuer's 2025 Annual Meeting of Stockholders, subject to the Reporting Person's continued service to the Issuer through the vesting date."}],"balance_after":11000,"derivative":{"exercise_price":21.77,"expiration_date":"2034-05-22","underlying":"Common Stock","underlying_shares":11000},"source":{"system":"sec-edgar","filing":"0000950170-24-065545","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000095017024065545/ownership.xml","form_type":"4"}},{"id":1511523,"issuer":{"id":6838,"kind":"organization","name":"Rallybio Corp","symbol":"RLYB"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Option (Right to Buy)","published_at":"2024-05-17T21:04:30.000Z","date":"2024-05-15","kind":"grant","planned":false,"acquired":true,"shares":16500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option was granted under the Company's 2021 Equity Incentive Plan. The option vests on the earlier of May 15, 2025 or the date of the Company's 2025 Annual Meeting of Stockholders."}],"balance_after":16500,"derivative":{"exercise_price":1.91,"expiration_date":"2034-05-15","underlying":"Common Stock","underlying_shares":16500},"source":{"system":"sec-edgar","filing":"0001739410-24-000090","document":"wk-form4_1715979851.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1739410/000173941024000090/wk-form4_1715979851.xml","form_type":"4"}},{"id":1782086,"issuer":{"id":1813,"kind":"organization","name":"Dianthus Therapeutics, Inc. /DE/","symbol":"DNTH"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2023-09-14T01:16:58.000Z","date":"2023-09-11","kind":"grant","planned":false,"acquired":true,"shares":6500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option represents a right to purchase a total of 6,500 shares of the Issuer's common stock, which will vest in full on the date that is the earlier of (i) the Issuer's 2024 Annual Meeting of Stockholders and (ii) September 11, 2024, subject to the Reporting Person's continued service to the Issuer."}],"balance_after":6500,"derivative":{"exercise_price":11.2,"expiration_date":"2033-09-10","underlying":"Common Stock","underlying_shares":6500},"source":{"system":"sec-edgar","filing":"0000899243-23-018866","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000089924323018866/doc4.xml","form_type":"4"}},{"id":1849614,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2023-06-20T21:30:34.000Z","date":"2023-06-13","kind":"grant","planned":false,"acquired":true,"shares":17060,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":17060,"derivative":{"exercise_price":20.18,"expiration_date":"2033-06-13","underlying":"Ordinary Shares","underlying_shares":17060},"source":{"system":"sec-edgar","filing":"0000904454-23-000402","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445423000402/edgar.xml","form_type":"4"}},{"id":1849613,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2023-06-20T21:30:34.000Z","date":"2023-06-16","kind":"sale","planned":false,"acquired":false,"shares":2275,"price":18.99,"value":43202.25,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F3","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"shares","element":"transactionShares","label":"F3","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.95 to $19.00. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":22423,"source":{"system":"sec-edgar","filing":"0000904454-23-000402","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445423000402/edgar.xml","form_type":"4"}},{"id":1849612,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2023-06-20T21:30:34.000Z","date":"2023-06-13","kind":"grant","planned":false,"acquired":true,"shares":8700,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":24698,"source":{"system":"sec-edgar","filing":"0000904454-23-000402","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445423000402/edgar.xml","form_type":"4"}},{"id":1884732,"issuer":{"id":6838,"kind":"organization","name":"Rallybio Corp","symbol":"RLYB"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Option (Right to Buy)","published_at":"2023-05-19T21:24:19.000Z","date":"2023-05-17","kind":"grant","planned":false,"acquired":true,"shares":15490,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option was granted under the Company's 2021 Equity Incentive Plan.  The option vests on the earlier of May 17, 2024 or the date of the Company's 2024 Annual Meeting of Stockholders."}],"balance_after":15490,"derivative":{"exercise_price":5.64,"expiration_date":"2033-05-17","underlying":"Common Stock","underlying_shares":15490},"source":{"system":"sec-edgar","filing":"0000899243-23-013402","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1739410/000089924323013402/doc4.xml","form_type":"4"}},{"id":1983800,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2023-03-01T21:16:53.000Z","date":"2023-02-27","kind":"sale","acquired":false,"shares":384,"price":19.97,"value":7668.48,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"shares","element":"transactionShares","label":"F1","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $19.92 to $20.01. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":15998,"source":{"system":"sec-edgar","filing":"0000899243-23-006589","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000089924323006589/doc4.xml","form_type":"4"}},{"id":2049706,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2023-01-20T20:57:30.000Z","date":"2023-01-18","kind":"exercise","acquired":false,"shares":6000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."}],"balance_after":2000,"derivative":{"exercise_price":5.37,"exercise_date":"2018-01-27","expiration_date":"2027-01-27","underlying":"Ordinary Shares","underlying_shares":6000},"source":{"system":"sec-edgar","filing":"0000904454-23-000031","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445423000031/edgar.xml","form_type":"4"}},{"id":2049705,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2023-01-20T20:57:30.000Z","date":"2023-01-18","kind":"sale","acquired":false,"shares":6000,"price":22.59,"value":135540.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."}],"balance_after":16382,"source":{"system":"sec-edgar","filing":"0000904454-23-000031","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445423000031/edgar.xml","form_type":"4"}},{"id":2049704,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2023-01-20T20:57:30.000Z","date":"2023-01-18","kind":"exercise","acquired":true,"shares":6000,"price":5.37,"value":32220.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."}],"balance_after":22382,"source":{"system":"sec-edgar","filing":"0000904454-23-000031","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445423000031/edgar.xml","form_type":"4"}},{"id":2085128,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2022-12-15T22:09:43.000Z","date":"2022-12-14","kind":"exercise","acquired":false,"shares":3800,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F2","text":"The Stock Option exercise price was EUR 10.10 per share or $10.69, as converted, based on the exchange rate at on December 13, 2022 of EUR 1 to $1.058."},{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The Stock Option was granted on June 6, 2013 and vested 25% after one year, with the remainder vesting in weekly installments over a two year period ending on June 10, 2016."}],"balance_after":0,"derivative":{"expiration_date":"2023-06-06","underlying":"Ordinary Shares","underlying_shares":3800},"source":{"system":"sec-edgar","filing":"0000904454-22-000633","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000633/edgar.xml","form_type":"4"}},{"id":2085127,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2022-12-15T22:09:43.000Z","date":"2022-12-13","kind":"exercise","acquired":false,"shares":3000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."}],"balance_after":8000,"derivative":{"exercise_price":5.37,"exercise_date":"2018-01-27","expiration_date":"2027-01-27","underlying":"Ordinary Shares","underlying_shares":3000},"source":{"system":"sec-edgar","filing":"0000904454-22-000633","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000633/edgar.xml","form_type":"4"}},{"id":2085126,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2022-12-15T22:09:43.000Z","date":"2022-12-14","kind":"sale","acquired":false,"shares":3800,"price":23.43,"value":89034.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."}],"balance_after":16382,"source":{"system":"sec-edgar","filing":"0000904454-22-000633","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000633/edgar.xml","form_type":"4"}},{"id":2085125,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2022-12-15T22:09:43.000Z","date":"2022-12-14","kind":"exercise","acquired":true,"shares":3800,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The Stock Option exercise price was EUR 10.10 per share or $10.69, as converted, based on the exchange rate at on December 13, 2022 of EUR 1 to $1.058."}],"balance_after":20182,"source":{"system":"sec-edgar","filing":"0000904454-22-000633","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000633/edgar.xml","form_type":"4"}},{"id":2085124,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2022-12-15T22:09:43.000Z","date":"2022-12-13","kind":"sale","acquired":false,"shares":3000,"price":23.45,"value":70350.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."}],"balance_after":16382,"source":{"system":"sec-edgar","filing":"0000904454-22-000633","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000633/edgar.xml","form_type":"4"}},{"id":2085123,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2022-12-15T22:09:43.000Z","date":"2022-12-13","kind":"exercise","acquired":true,"shares":3000,"price":5.37,"value":16110.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."}],"balance_after":19382,"source":{"system":"sec-edgar","filing":"0000904454-22-000633","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000633/edgar.xml","form_type":"4"}},{"id":2100086,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2022-12-01T21:14:30.000Z","date":"2022-11-29","kind":"exercise","acquired":false,"shares":6200,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F2","text":"The Stock Option exercise price was EUR 10.10 per share or $10.46, as converted, based on the exchange rate at exercise of EUR 1 to $1.036."},{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The Stock Option was granted on June 6, 2013 and vested 25% after one year, with the remainder vesting in weekly installments over a two year period ending on June 10, 2016."}],"balance_after":3800,"derivative":{"expiration_date":"2023-06-06","underlying":"Ordinary Shares","underlying_shares":6200},"source":{"system":"sec-edgar","filing":"0000904454-22-000601","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000601/edgar.xml","form_type":"4"}},{"id":2100085,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2022-12-01T21:14:30.000Z","date":"2022-11-29","kind":"sale","acquired":false,"shares":6200,"price":25.38,"value":157356.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $25.33 to $25.48. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":16382,"source":{"system":"sec-edgar","filing":"0000904454-22-000601","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000601/edgar.xml","form_type":"4"}},{"id":2100084,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2022-12-01T21:14:30.000Z","date":"2022-11-29","kind":"exercise","acquired":true,"shares":6200,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The reported transactions were effected pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The Stock Option exercise price was EUR 10.10 per share or $10.46, as converted, based on the exchange rate at exercise of EUR 1 to $1.036."}],"balance_after":22582,"source":{"system":"sec-edgar","filing":"0000904454-22-000601","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000601/edgar.xml","form_type":"4"}},{"id":2227954,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2022-06-17T20:31:47.000Z","date":"2022-06-15","kind":"grant","acquired":true,"shares":17810,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":17810,"derivative":{"exercise_price":14.08,"expiration_date":"2032-06-15","underlying":"Ordinary Shares","underlying_shares":17810},"source":{"system":"sec-edgar","filing":"0000904454-22-000356","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000356/edgar.xml","form_type":"4"}},{"id":2227953,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2022-06-17T20:31:47.000Z","date":"2022-06-15","kind":"grant","acquired":true,"shares":9080,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated. Each restricted share unit represents the contingent right to receive one Ordinary Share. The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":16382,"source":{"system":"sec-edgar","filing":"0000904454-22-000356","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000356/edgar.xml","form_type":"4"}},{"id":2255333,"issuer":{"id":6838,"kind":"organization","name":"Rallybio Corp","symbol":"RLYB"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Option (Right to Buy)","published_at":"2022-05-27T00:11:35.000Z","date":"2022-05-24","kind":"grant","acquired":true,"shares":13440,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option was granted under the Company's 2021 Equity Incentive Plan.  The option vests on the earlier of May 24, 2023 or the date of the Company's 2023 Annual Meeting of Stockholders."}],"balance_after":13440,"derivative":{"exercise_price":12.75,"expiration_date":"2032-05-24","underlying":"Common Stock","underlying_shares":13440},"source":{"system":"sec-edgar","filing":"0000899243-22-019834","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1739410/000089924322019834/doc4.xml","form_type":"4"}},{"id":2360858,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2022-03-02T22:26:20.000Z","date":"2022-02-28","kind":"sale","acquired":false,"shares":596,"price":16.87,"value":10054.52,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"shares","element":"transactionShares","label":"F1","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price.  The shares were sold in multiple transactions at prices ranging from $16.82 to $16.88.  The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":7302,"source":{"system":"sec-edgar","filing":"0000904454-22-000211","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000211/edgar.xml","form_type":"4"}},{"id":2369101,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2022-02-28T23:15:19.000Z","date":"2022-02-24","kind":"grant","acquired":true,"shares":2645,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":2645,"derivative":{"exercise_price":16.04,"expiration_date":"2032-02-24","underlying":"Ordinary Shares","underlying_shares":2645},"source":{"system":"sec-edgar","filing":"0000904454-22-000189","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000189/edgar.xml","form_type":"4"}},{"id":2369100,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2022-02-28T23:15:19.000Z","date":"2022-02-24","kind":"grant","acquired":true,"shares":1534,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated.  Each restricted share unit represents the contingent right to receive one Ordinary Share.  The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":7898,"source":{"system":"sec-edgar","filing":"0000904454-22-000189","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445422000189/edgar.xml","form_type":"4"}},{"id":2444196,"issuer":{"id":6838,"kind":"organization","name":"Rallybio Corp","symbol":"RLYB"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Option (Right to Buy)","published_at":"2022-01-06T01:37:35.000Z","date":"2022-01-03","kind":"grant","acquired":true,"shares":5369,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests as to the underlying shares of Common Stock in 12 equal installments, each on the last day of each month of calendar year 2022."}],"balance_after":5369,"derivative":{"exercise_price":10.38,"expiration_date":"2032-01-03","underlying":"Common Stock","underlying_shares":5369},"source":{"system":"sec-edgar","filing":"0000899243-22-001056","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1739410/000089924322001056/doc4.xml","form_type":"4"}},{"id":2808996,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2021-03-04T19:19:23.000Z","date":"2021-03-02","kind":"sale","acquired":false,"shares":504,"price":37.6,"value":18950.4,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"shares","element":"transactionShares","label":"F1","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price.  The shares were sold in multiple transactions at prices ranging from $36.76 to $37.60.  The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":6364,"source":{"system":"sec-edgar","filing":"0000904454-21-000293","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445421000293/edgar.xml","form_type":"4"}},{"id":2826600,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2021-03-01T21:23:08.000Z","date":"2021-02-25","kind":"grant","acquired":true,"shares":4107,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":4107,"derivative":{"exercise_price":37,"expiration_date":"2031-02-25","underlying":"Ordinary Shares","underlying_shares":4107},"source":{"system":"sec-edgar","filing":"0000904454-21-000261","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445421000261/edgar.xml","form_type":"4"}},{"id":2826599,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2021-03-01T21:23:08.000Z","date":"2021-02-25","kind":"grant","acquired":true,"shares":2382,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated.  Each restricted share unit represents the contingent right to receive one Ordinary Share.  The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":6868,"source":{"system":"sec-edgar","filing":"0000904454-21-000261","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445421000261/edgar.xml","form_type":"4"}},{"id":3238392,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2020-03-02T20:49:02.000Z","date":"2020-02-27","kind":"grant","acquired":true,"shares":3620,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":3620,"derivative":{"exercise_price":51.81,"expiration_date":"2030-02-27","underlying":"Ordinary Shares","underlying_shares":3620},"source":{"system":"sec-edgar","filing":"0000904454-20-000259","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445420000259/edgar.xml","form_type":"4"}},{"id":3238391,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2020-03-02T20:49:02.000Z","date":"2020-02-27","kind":"grant","acquired":true,"shares":2063,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated.  Each restricted share unit represents the contingent right to receive one Ordinary Share.  The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":4486,"source":{"system":"sec-edgar","filing":"0000904454-20-000259","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445420000259/edgar.xml","form_type":"4"}},{"id":3288830,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2020-02-05T18:19:40.000Z","date":"2020-02-05","kind":"sale","acquired":false,"shares":822,"price":61.53,"value":50577.66,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price.  The shares were sold in multiple transactions at prices ranging from $61.13 to $61.85.  The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":2423,"source":{"system":"sec-edgar","filing":"0000904454-20-000154","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445420000154/edgar.xml","form_type":"4"}},{"id":3288829,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2020-02-05T18:19:40.000Z","date":"2020-02-05","kind":"sale","acquired":false,"shares":1300,"price":60.58,"value":78754.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price.  The shares were sold in multiple transactions at prices ranging from $60.10 to $60.97.  The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":3245,"source":{"system":"sec-edgar","filing":"0000904454-20-000154","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445420000154/edgar.xml","form_type":"4"}},{"id":3297749,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2020-01-31T02:15:04.000Z","date":"2020-01-28","kind":"sale","acquired":false,"shares":807,"price":62.19,"value":50187.33,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"shares","element":"transactionShares","label":"F1","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price.  The shares were sold in multiple transactions at prices ranging from $61.46 to $62.20.  The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":4545,"source":{"system":"sec-edgar","filing":"0000904454-20-000116","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445420000116/edgar.xml","form_type":"4"}},{"id":3315297,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2020-01-08T18:48:31.000Z","date":"2020-01-07","kind":"sale","acquired":false,"shares":3000,"price":72.18,"value":216540.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price.  The shares were sold in multiple transactions at prices ranging from $71.79 to $72.62.  The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":5352,"source":{"system":"sec-edgar","filing":"0000904454-20-000011","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445420000011/edgar.xml","form_type":"4"}},{"id":3339146,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-12-17T21:06:01.000Z","date":"2019-12-13","kind":"exercise","acquired":true,"shares":2000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The Stock Option vested on January 27, 2018, the first anniversary of the grant date."}],"balance_after":9000,"derivative":{"exercise_price":5.37,"expiration_date":"2027-01-27","underlying":"Ordinary Shares","underlying_shares":2000},"source":{"system":"sec-edgar","filing":"0000904454-19-000749","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445419000749/edgar.xml","form_type":"4"}},{"id":3339145,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2019-12-17T21:06:01.000Z","date":"2019-12-13","kind":"sale","acquired":false,"shares":2000,"price":70.5,"value":141000.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price.  The shares were sold in multiple transactions at prices ranging from $70.50 to $70.51.  The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":8352,"source":{"system":"sec-edgar","filing":"0000904454-19-000749","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445419000749/edgar.xml","form_type":"4"}},{"id":3339144,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2019-12-17T21:06:01.000Z","date":"2019-12-13","kind":"exercise","acquired":true,"shares":2000,"price":5.37,"value":10740.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."}],"balance_after":10352,"source":{"system":"sec-edgar","filing":"0000904454-19-000749","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445419000749/edgar.xml","form_type":"4"}},{"id":3348250,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2019-12-09T23:30:59.000Z","date":"2019-12-09","kind":"sale","acquired":false,"shares":2500,"price":67.5,"value":168750.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."}],"balance_after":8352,"source":{"system":"sec-edgar","filing":"0000904454-19-000737","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445419000737/edgar.xml","form_type":"4"}},{"id":3348249,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2019-12-09T23:30:59.000Z","date":"2019-12-06","kind":"sale","acquired":false,"shares":7382,"price":64.39,"value":475326.98,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price.  The shares were sold in multiple transactions at prices ranging from $64.32 to $64.50.  The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":10852,"source":{"system":"sec-edgar","filing":"0000904454-19-000737","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445419000737/edgar.xml","form_type":"4"}},{"id":3348248,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2019-12-09T23:30:59.000Z","date":"2019-12-06","kind":"sale","acquired":false,"shares":1700,"price":63.69,"value":108273.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold pursuant to a sales plan adopted by the Reporting Person and intended to comply with Rule 10b5-1 under the Securities Exchange Act of 1934."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price.  The shares were sold in multiple transactions at prices ranging from $63.20 to $64.03.  The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":18234,"source":{"system":"sec-edgar","filing":"0000904454-19-000737","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445419000737/edgar.xml","form_type":"4"}},{"id":3404518,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Option (right to buy)","published_at":"2019-09-30T21:52:33.000Z","date":"2019-09-26","kind":"exercise","acquired":false,"shares":205479,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The shares vest as follows: 1/4th of the shares vest one year after January 3, 2017;1/48th of the shares vest monthly thereafter over the next three years."}],"balance_after":102740,"derivative":{"exercise_price":12.21,"expiration_date":"2027-06-04","underlying":"Common Stock","underlying_shares":205479},"source":{"system":"sec-edgar","filing":"0001209191-19-051139","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":9,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119051139/doc4.xml","form_type":"4"}},{"id":3404517,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Option (right to buy)","published_at":"2019-09-30T21:52:33.000Z","date":"2019-09-26","kind":"exercise","acquired":false,"shares":145303,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares vest as follows: 1/4th of the shares vest one year after January 4, 2016;1/48th of the shares vest monthly thereafter over the next three years."}],"balance_after":13209,"derivative":{"exercise_price":6.48,"expiration_date":"2026-02-16","underlying":"Common Stock","underlying_shares":145303},"source":{"system":"sec-edgar","filing":"0001209191-19-051139","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119051139/doc4.xml","form_type":"4"}},{"id":3404516,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Option (right to buy)","published_at":"2019-09-30T21:52:33.000Z","date":"2019-09-26","kind":"exercise","acquired":false,"shares":1711079,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares vest as follows: 1/4th of the shares vest one year after January 1, 2015;1/48th of the shares vest monthly thereafter over the next three years."}],"balance_after":0,"derivative":{"exercise_price":6.48,"expiration_date":"2025-12-15","underlying":"Common Stock","underlying_shares":1711079},"source":{"system":"sec-edgar","filing":"0001209191-19-051139","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119051139/doc4.xml","form_type":"4"}},{"id":3404515,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2019-09-30T21:52:33.000Z","date":"2019-09-26","kind":"tax_withholding","acquired":false,"shares":175064,"price":16.64,"value":2913064.96,"ownership":{"direct":true},"balance_after":678149,"source":{"system":"sec-edgar","filing":"0001209191-19-051139","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119051139/doc4.xml","form_type":"4"}},{"id":3404514,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2019-09-30T21:52:33.000Z","date":"2019-09-26","kind":"exercise","acquired":true,"shares":205479,"price":12.21,"value":2508898.59,"ownership":{"direct":true},"balance_after":853213,"source":{"system":"sec-edgar","filing":"0001209191-19-051139","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119051139/doc4.xml","form_type":"4"}},{"id":3404513,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2019-09-30T21:52:33.000Z","date":"2019-09-26","kind":"tax_withholding","acquired":false,"shares":95156,"price":16.64,"value":1583395.84,"ownership":{"direct":true},"balance_after":647734,"source":{"system":"sec-edgar","filing":"0001209191-19-051139","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119051139/doc4.xml","form_type":"4"}},{"id":3404512,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2019-09-30T21:52:33.000Z","date":"2019-09-26","kind":"exercise","acquired":true,"shares":145303,"price":6.48,"value":941563.44,"ownership":{"direct":true},"balance_after":742890,"source":{"system":"sec-edgar","filing":"0001209191-19-051139","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119051139/doc4.xml","form_type":"4"}},{"id":3404511,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2019-09-30T21:52:33.000Z","date":"2019-09-26","kind":"tax_withholding","acquired":false,"shares":1113492,"price":16.64,"value":18528506.88,"ownership":{"direct":true},"balance_after":597587,"source":{"system":"sec-edgar","filing":"0001209191-19-051139","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119051139/doc4.xml","form_type":"4"}},{"id":3404510,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2019-09-30T21:52:33.000Z","date":"2019-09-26","kind":"exercise","acquired":true,"shares":1711079,"price":6.48,"value":11087791.92,"ownership":{"direct":true},"balance_after":1711079,"source":{"system":"sec-edgar","filing":"0001209191-19-051139","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119051139/doc4.xml","form_type":"4"}},{"id":3559506,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Option (right to buy)","published_at":"2019-04-09T22:59:06.000Z","date":"2019-04-08","kind":"exercise","acquired":false,"shares":1787,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The shares vest as follows: 1/4th of the shares vest one year after January 1, 2015;1/48th of the shares vest monthly thereafter over the next three years."}],"balance_after":1711079,"derivative":{"exercise_price":6.48,"expiration_date":"2025-12-15","underlying":"Common Stock","underlying_shares":1787},"source":{"system":"sec-edgar","filing":"0001209191-19-024175","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119024175/doc4.xml","form_type":"4"}},{"id":3559505,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Option (right to buy)","published_at":"2019-04-09T22:59:06.000Z","date":"2019-04-05","kind":"exercise","acquired":false,"shares":30000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The shares vest as follows: 1/4th of the shares vest one year after January 1, 2015;1/48th of the shares vest monthly thereafter over the next three years."}],"balance_after":1712866,"derivative":{"exercise_price":6.48,"expiration_date":"2025-12-15","underlying":"Common Stock","underlying_shares":30000},"source":{"system":"sec-edgar","filing":"0001209191-19-024175","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119024175/doc4.xml","form_type":"4"}},{"id":3559504,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2019-04-09T22:59:06.000Z","date":"2019-04-08","kind":"sale","acquired":false,"shares":1787,"price":32.1658,"value":57480.2846,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The weighted average sale price for the transaction reported was $32.1658, and the range of prices were between $32.11 and $32.20.  Upon request by the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001209191-19-024175","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119024175/doc4.xml","form_type":"4"}},{"id":3559503,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2019-04-09T22:59:06.000Z","date":"2019-04-08","kind":"exercise","acquired":true,"shares":1787,"price":6.48,"value":11579.76,"ownership":{"direct":true},"balance_after":1787,"source":{"system":"sec-edgar","filing":"0001209191-19-024175","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119024175/doc4.xml","form_type":"4"}},{"id":3559502,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2019-04-09T22:59:06.000Z","date":"2019-04-05","kind":"sale","acquired":false,"shares":30000,"price":32.11,"value":963300.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001209191-19-024175","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119024175/doc4.xml","form_type":"4"}},{"id":3559501,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2019-04-09T22:59:06.000Z","date":"2019-04-05","kind":"exercise","acquired":true,"shares":30000,"price":6.48,"value":194400.0,"ownership":{"direct":true},"balance_after":30000,"source":{"system":"sec-edgar","filing":"0001209191-19-024175","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119024175/doc4.xml","form_type":"4"}},{"id":3606495,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Option (right to buy)","published_at":"2019-03-07T22:20:44.000Z","date":"2019-03-06","kind":"exercise","acquired":false,"shares":18386,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The shares vest as follows: 1/4th of the shares vest one year after January 1, 2015;1/48th of the shares vest monthly thereafter over the next three years."}],"balance_after":1742866,"derivative":{"exercise_price":6.48,"expiration_date":"2025-12-15","underlying":"Common Stock","underlying_shares":18386},"source":{"system":"sec-edgar","filing":"0001209191-19-017835","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119017835/doc4.xml","form_type":"4"}},{"id":3606494,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2019-03-07T22:20:44.000Z","date":"2019-03-06","kind":"sale","acquired":false,"shares":18386,"price":32.1362,"value":590856.1732,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The weighted average sale price for the transaction reported was $32.1362, and the range of prices were between $32.11 and $32.50.  Upon request by the SEC staff, the issuer, or any security holder of the issuer, full information regarding the number of shares sold at each separate price will be provided."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001209191-19-017835","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119017835/doc4.xml","form_type":"4"}},{"id":3606493,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2019-03-07T22:20:44.000Z","date":"2019-03-06","kind":"exercise","acquired":true,"shares":18386,"price":6.48,"value":119141.28,"ownership":{"direct":true},"balance_after":18386,"source":{"system":"sec-edgar","filing":"0001209191-19-017835","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119017835/doc4.xml","form_type":"4"}},{"id":3682674,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2019-01-30T22:28:06.000Z","date":"2019-01-28","kind":"sale","acquired":false,"shares":1210,"price":31.32,"value":37897.2,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"shares","element":"transactionShares","label":"F1","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price.  The shares were sold in multiple transactions at prices ranging from $31.26 to $31.46.  The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":19934,"source":{"system":"sec-edgar","filing":"0000904454-19-000132","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445419000132/edgar.xml","form_type":"4"}},{"id":3683906,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-01-30T01:37:38.000Z","date":"2019-01-25","kind":"grant","acquired":true,"shares":5295,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":5295,"derivative":{"exercise_price":31.71,"expiration_date":"2029-01-25","underlying":"Ordinary Shares","underlying_shares":5295},"source":{"system":"sec-edgar","filing":"0000904454-19-000111","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445419000111/edgar.xml","form_type":"4"}},{"id":3683905,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2019-01-30T01:37:38.000Z","date":"2019-01-25","kind":"grant","acquired":true,"shares":3230,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated.  Each restricted share unit represents the contingent right to receive one Ordinary Share.  The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":21144,"source":{"system":"sec-edgar","filing":"0000904454-19-000111","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445419000111/edgar.xml","form_type":"4"}},{"id":3704249,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Option (right to buy)","published_at":"2019-01-04T22:32:03.000Z","date":"2019-01-02","kind":"grant","acquired":true,"shares":296000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares vest as follows: 1/4th of the shares vest one year after January 2, 2019; 1/48th of the shares vest monthly thereafter over the next three years."}],"balance_after":296000,"derivative":{"exercise_price":30.73,"expiration_date":"2029-01-01","underlying":"Common Stock","underlying_shares":296000},"source":{"system":"sec-edgar","filing":"0001209191-19-002143","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919119002143/doc4.xml","form_type":"4"}},{"id":4083623,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2018-01-31T15:51:06.000Z","date":"2018-01-29","kind":"sale","acquired":false,"shares":2878,"price":18.53,"value":53329.34,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"As required by the relevant Restricted Share Unit Agreement, the Reporting Person sold the Ordinary Shares and remitted the proceeds therefrom to the Issuer to satisfy estimated tax withholding obligations triggered by the vesting of restricted share units."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $18.41 to $18.69. The Reporting Person undertakes to provide to the Issuer, any shareholder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":17914,"source":{"system":"sec-edgar","filing":"0000904454-18-000095","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445418000095/edgar.xml","form_type":"4"}},{"id":4084898,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2018-01-30T15:46:03.000Z","date":"2018-01-26","kind":"grant","acquired":true,"shares":6390,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The Stock Option vests 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."}],"balance_after":6390,"derivative":{"exercise_price":19.39,"expiration_date":"2028-01-26","underlying":"Ordinary Shares","underlying_shares":6390},"source":{"system":"sec-edgar","filing":"0000904454-18-000064","document":"edgar.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445418000064/edgar.xml","form_type":"4"}},{"id":4084897,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Ordinary Shares","published_at":"2018-01-30T15:46:03.000Z","date":"2018-01-26","kind":"grant","acquired":true,"shares":4792,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents restricted share units granted to the Reporting Person under the Issuer's 2014 Share Incentive Plan, as amended and restated.  Each restricted share unit represents the contingent right to receive one Ordinary Share.  The restricted share units vest 100% on the first anniversary of the date of grant, subject to the Reporting Person's continued relationship with the Issuer through such date."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes (i) 5,000 restricted share units that vested in full on January 27, 2017 previously disclosed by the Reporting Person in Table II and (ii) 11,000 restricted share units that vested in full on January 27, 2018 previously disclosed by the Reporting Person in Table II."}],"balance_after":20792,"source":{"system":"sec-edgar","filing":"0000904454-18-000064","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000090445418000064/edgar.xml","form_type":"4"}},{"id":4107689,"issuer":{"id":145982,"kind":"organization","name":"AKCEA THERAPEUTICS, INC.","symbol":"AKCA"},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Stock Option (right to buy)","published_at":"2018-01-05T00:02:39.000Z","date":"2018-01-02","kind":"grant","acquired":true,"shares":275000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares vest as follows: 1/4th of the shares vest one year after January 2, 2018; 1/48th of the shares vest monthly thereafter over the next three years."}],"balance_after":275000,"derivative":{"exercise_price":17.38,"expiration_date":"2028-01-01","underlying":"Common Stock","underlying_shares":275000},"source":{"system":"sec-edgar","filing":"0001209191-18-002240","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000120919118002240/doc4.xml","form_type":"4"}},{"id":4475437,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Restricted Stock Units","published_at":"2017-01-31T20:03:47.000Z","date":"2017-01-27","kind":"grant","acquired":true,"shares":11000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The Restricted Stock Unit vests 100% on January 27, 2018."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"Expiration date is not applicable as the vested Restricted Stock Units shall be settled on the first business day following the date that such Restricted Stock Units vests."}],"balance_after":16000,"derivative":{"exercise_price":0,"exercise_date":"2020-01-27","underlying":"Ordinary Shares","underlying_shares":11000},"source":{"system":"sec-edgar","filing":"0001140361-17-003704","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000114036117003704/doc1.xml","form_type":"4"}},{"id":4475436,"issuer":{"id":4162,"kind":"organization","name":"uniQure N.V."},"owners":[{"id":44740,"kind":"person","name":"Soteropoulos Paula","position":1,"cik":"0001692444","reported_name":"Soteropoulos Paula","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2017-01-31T20:03:47.000Z","date":"2017-01-27","kind":"grant","acquired":true,"shares":11000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The Stock Option vests 100% on January 27, 2018."}],"balance_after":11000,"derivative":{"exercise_price":5.37,"expiration_date":"2027-01-27","underlying":"Ordinary Shares","underlying_shares":11000},"source":{"system":"sec-edgar","filing":"0001140361-17-003704","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1692444/000114036117003704/doc1.xml","form_type":"4"}}]}