{"transactions":[{"id":763766,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2026-05-26T20:30:33.000Z","date":"2026-05-21","kind":"grant","planned":false,"acquired":true,"shares":1700,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares vest on the first anniversary of the Grant Date, provided that the Option will in any case be fully vested on the date of Company's 2027 annual stockholder meeting, subject to the Reporting Person's Continuous Service (as defined in the 2020 Equity Incentive Plan (the \"Plan\")) through such vesting date and will vest in full upon a Change in Control (as defined in the Plan)."}],"balance_after":1700,"derivative":{"exercise_price":52.7,"expiration_date":"2036-05-20","underlying":"Common Stock","underlying_shares":1700},"source":{"system":"sec-edgar","filing":"0001822557-26-000002","document":"form4-05262026_040508.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000182255726000002/form4-05262026_040508.xml","form_type":"4"}},{"id":969471,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-12-15T23:50:10.000Z","date":"2025-12-11","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":400,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"shares","element":"transactionShares","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on December 11, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option are fully vested and exercisable."}],"balance_after":0,"derivative":{"exercise_price":169.5,"expiration_date":"2033-05-24","underlying":"Common Stock","underlying_shares":400},"source":{"system":"sec-edgar","filing":"0001822557-25-000007","document":"form4-12152025_111206.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":10,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000182255725000007/form4-12152025_111206.xml","form_type":"4"}},{"id":969470,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-12-15T23:50:10.000Z","date":"2025-12-11","kind":"grant","planned":false,"acquired":true,"shares":400,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on December 11, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option are fully vested and exercisable."}],"balance_after":400,"derivative":{"exercise_price":104.13,"expiration_date":"2033-05-24","underlying":"Common Stock","underlying_shares":400},"source":{"system":"sec-edgar","filing":"0001822557-25-000007","document":"form4-12152025_111206.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":9,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000182255725000007/form4-12152025_111206.xml","form_type":"4"}},{"id":969469,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2025-12-15T23:50:10.000Z","date":"2025-12-11","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":133,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"shares","element":"transactionShares","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on December 11, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option are fully vested and exercisable."}],"balance_after":0,"derivative":{"exercise_price":1143,"expiration_date":"2031-05-19","underlying":"Common Stock","underlying_shares":133},"source":{"system":"sec-edgar","filing":"0001822557-25-000007","document":"form4-12152025_111206.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000182255725000007/form4-12152025_111206.xml","form_type":"4"}},{"id":969468,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2025-12-15T23:50:10.000Z","date":"2025-12-11","kind":"grant","planned":false,"acquired":true,"shares":133,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on December 11, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option are fully vested and exercisable."}],"balance_after":133,"derivative":{"exercise_price":104.13,"expiration_date":"2031-05-19","underlying":"Common Stock","underlying_shares":133},"source":{"system":"sec-edgar","filing":"0001822557-25-000007","document":"form4-12152025_111206.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000182255725000007/form4-12152025_111206.xml","form_type":"4"}},{"id":969467,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-12-15T23:50:10.000Z","date":"2025-12-11","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":362,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"shares","element":"transactionShares","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on December 11, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option are fully vested and exercisable."}],"balance_after":0,"derivative":{"exercise_price":230.25,"expiration_date":"2030-08-06","underlying":"Common Stock","underlying_shares":362},"source":{"system":"sec-edgar","filing":"0001822557-25-000007","document":"form4-12152025_111206.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000182255725000007/form4-12152025_111206.xml","form_type":"4"}},{"id":969466,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-12-15T23:50:10.000Z","date":"2025-12-11","kind":"grant","planned":false,"acquired":true,"shares":362,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on December 11, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option are fully vested and exercisable."}],"balance_after":362,"derivative":{"exercise_price":104.13,"expiration_date":"2030-08-06","underlying":"Common Stock","underlying_shares":362},"source":{"system":"sec-edgar","filing":"0001822557-25-000007","document":"form4-12152025_111206.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000182255725000007/form4-12152025_111206.xml","form_type":"4"}},{"id":969465,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-12-15T23:50:10.000Z","date":"2025-12-11","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":309,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"shares","element":"transactionShares","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on December 11, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option are fully vested and exercisable."}],"balance_after":0,"derivative":{"exercise_price":123,"expiration_date":"2030-06-07","underlying":"Common Stock","underlying_shares":309},"source":{"system":"sec-edgar","filing":"0001822557-25-000007","document":"form4-12152025_111206.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000182255725000007/form4-12152025_111206.xml","form_type":"4"}},{"id":969464,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-12-15T23:50:10.000Z","date":"2025-12-11","kind":"grant","planned":false,"acquired":true,"shares":309,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on December 11, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option are fully vested and exercisable."}],"balance_after":309,"derivative":{"exercise_price":104.13,"expiration_date":"2030-06-07","underlying":"Common Stock","underlying_shares":309},"source":{"system":"sec-edgar","filing":"0001822557-25-000007","document":"form4-12152025_111206.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000182255725000007/form4-12152025_111206.xml","form_type":"4"}},{"id":969463,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-12-15T23:50:10.000Z","date":"2025-12-11","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":173,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"shares","element":"transactionShares","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on December 11, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option are fully vested and exercisable."}],"balance_after":0,"derivative":{"exercise_price":108,"expiration_date":"2029-07-22","underlying":"Common Stock","underlying_shares":173},"source":{"system":"sec-edgar","filing":"0001822557-25-000007","document":"form4-12152025_111206.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000182255725000007/form4-12152025_111206.xml","form_type":"4"}},{"id":969462,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-12-15T23:50:10.000Z","date":"2025-12-11","kind":"grant","planned":false,"acquired":true,"shares":173,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Effective August 4, 2025, the Issuer effected a reverse stock split (the \"Reverse Split\") whereby every seventy-five shares of its issued and outstanding Common Stock were automatically combined into one share of Common Stock. In connection with the Reverse Split, each stock option to purchase 75 shares of Common Stock was automatically combined into a stock option to purchase one share of Common Stock and the exercise prices of such options were multiplied by seventy-five."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transactions reported herein reflect a one-time stock option repricing (the \"Option Repricing\") effective on December 11, 2025 (the \"Repricing Date\"). The Option Repricing applies to options with exercise prices of $106.09 per share or greater held by employees and directors of the Issuer who remained in continuous service with the Company as of the Repricing Date."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"Pursuant to the Option Repricing, the exercise price of the repriced options has been amended to reduce the exercise price to $104.13 per share, the thirty (30)-day trailing volume-weighted average price of the Common Stock on the Nasdaq Capital Market on the Repricing Date. However, if an optionholder exercises a repriced option before the end of a retention period of one year (which period may be shorter in certain circumstances), such optionholder will be required to pay the original exercise price per share of such repriced option. No other changes were made to the repriced options in connection with the Option Repricing, including with respect to the vesting schedules, expiration dates or number of shares underlying such repriced options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option are fully vested and exercisable."}],"balance_after":173,"derivative":{"exercise_price":104.13,"expiration_date":"2029-07-22","underlying":"Common Stock","underlying_shares":173},"source":{"system":"sec-edgar","filing":"0001822557-25-000007","document":"form4-12152025_111206.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000182255725000007/form4-12152025_111206.xml","form_type":"4"}},{"id":1034169,"issuer":{"id":8336,"kind":"organization","name":"GRI Bio, Inc."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-09-22T20:05:53.000Z","date":"2025-09-18","kind":"grant","planned":false,"acquired":true,"shares":23605,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Options to purchase 17,621 shares vested in full upon the date of grant and options to purchase 5,984 shares will vest in four substantially equal quarterly installments such that the stock option is fully vested on the first anniversary of the date of grant."}],"balance_after":23605,"derivative":{"exercise_price":1.93,"expiration_date":"2035-09-18","underlying":"Common Stock","underlying_shares":23605},"source":{"system":"sec-edgar","filing":"0001822557-25-000005","document":"wk-form4_1758571550.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822557/000182255725000005/wk-form4_1758571550.xml","form_type":"4"}},{"id":1054268,"issuer":{"id":8336,"kind":"organization","name":"GRI Bio, Inc."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-08-27T12:24:51.000Z","date":"2025-08-26","kind":"grant","planned":false,"acquired":true,"shares":5994,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Options to purchase 4,044 shares vested in full upon the date of grant and options to purchase 1,950 shares will vest in four substantially equal quarterly installments such that the stock option is fully vested on the first anniversary of the date of grant."}],"balance_after":5994,"derivative":{"exercise_price":1.41,"expiration_date":"2035-08-26","underlying":"Common Stock","underlying_shares":5994},"source":{"system":"sec-edgar","filing":"0001824293-25-000139","document":"wk-form4_1756297487.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822557/000182429325000139/wk-form4_1756297487.xml","form_type":"4"}},{"id":1066077,"issuer":{"id":8336,"kind":"organization","name":"GRI Bio, Inc."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-08-14T20:58:44.000Z","date":"2025-08-13","kind":"grant","planned":false,"acquired":true,"shares":4527,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The stock option vests in 4 equal quarterly installments such that the stock option is fully vested on the first anniversary of the date of grant."}],"balance_after":4527,"derivative":{"exercise_price":1.3,"expiration_date":"2035-08-13","underlying":"Common Stock","underlying_shares":4527},"source":{"system":"sec-edgar","filing":"0001824293-25-000119","document":"wk-form4_1755205119.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822557/000182429325000119/wk-form4_1755205119.xml","form_type":"4"}},{"id":1082140,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-07-24T23:38:01.000Z","date":"2025-07-22","kind":"grant","planned":false,"acquired":true,"shares":30000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares vest on the first anniversary of the Grant Date, provided that the Option will in any case be fully vested on the date of Company's 2026 annual stockholder meeting, subject to the Reporting Person's Continuous Service (as defined in the 2020 Equity Incentive Plan (the \"Plan\")) through such vesting date and will vest in full upon a Change in Control (as defined in the Plan)."}],"balance_after":30000,"derivative":{"exercise_price":0.1162,"expiration_date":"2035-07-21","underlying":"Common Stock","underlying_shares":30000},"source":{"system":"sec-edgar","filing":"0001415889-25-020269","document":"form4-07242025_110757.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000141588925020269/form4-07242025_110757.xml","form_type":"4"}},{"id":1295292,"issuer":{"id":8336,"kind":"organization","name":"GRI Bio, Inc."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-01-24T22:57:55.000Z","date":"2025-01-23","kind":"grant","planned":false,"acquired":true,"shares":30297,"price":0.6857,"value":20774.6529,"ownership":{"direct":true},"balance_after":30297,"derivative":{"exercise_price":0.6857,"exercise_date":"2025-01-23","expiration_date":"2035-01-23","underlying":"Common Stock","underlying_shares":30297},"source":{"system":"sec-edgar","filing":"0001824293-25-000032","document":"wk-form4_1737759469.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822557/000182429325000032/wk-form4_1737759469.xml","form_type":"4"}},{"id":1502092,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2024-05-24T20:27:37.000Z","date":"2024-05-22","kind":"grant","planned":false,"acquired":true,"shares":30000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares vest on the first anniversary of the Grant Date, provided that the Option will in any case be fully vested on the date of Company's 2025 annual stockholder meeting, subject to the Reporting Person's Continuous Service (as defined in the 2020 Equity Incentive Plan (the \"Plan\")) through such vesting date and will vest in full upon a Change in Control (as defined in the Plan)."}],"balance_after":30000,"derivative":{"exercise_price":0.7511,"expiration_date":"2034-05-21","underlying":"Common Stock","underlying_shares":30000},"source":{"system":"sec-edgar","filing":"0001415889-24-014492","document":"form4-05242024_080514.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000141588924014492/form4-05242024_080514.xml","form_type":"4"}},{"id":1808113,"issuer":{"id":8336,"kind":"organization","name":"GRI Bio, Inc."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2023-08-14T20:07:42.000Z","date":"2023-08-10","kind":"grant","planned":false,"acquired":true,"shares":34483,"price":2.9,"value":100000.7,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Vests as to 1/12th of the underlying shares of common stock on the date of grant, then in 11 equal quarterly installments such that the stock option is fully vested on the third annual anniversary of the date of grant."}],"balance_after":34483,"derivative":{"exercise_price":2.9,"expiration_date":"2033-08-10","underlying":"Common Stock","underlying_shares":34483},"source":{"system":"sec-edgar","filing":"0001824293-23-000154","document":"wk-form4_1692043648.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822557/000182429323000154/wk-form4_1692043648.xml","form_type":"4"}},{"id":1876603,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2023-05-26T21:39:51.000Z","date":"2023-05-25","kind":"grant","planned":false,"acquired":true,"shares":30000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares vest on the first anniversary of the Grant Date, provided that the Option will in any case be fully vested on the date of Company's 2024 annual stockholder meeting, subject to the Reporting Person's Continuous Service (as defined in the 2020 Equity Incentive Plan (the \"Plan\")) through such vesting date and will vest in full upon a Change in Control (as defined in the Plan)."}],"balance_after":30000,"derivative":{"exercise_price":2.26,"expiration_date":"2033-05-24","underlying":"Common Stock","underlying_shares":30000},"source":{"system":"sec-edgar","filing":"0001209191-23-032661","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000120919123032661/doc4.xml","form_type":"4"}},{"id":2253524,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2022-05-27T20:06:57.000Z","date":"2022-05-25","kind":"grant","acquired":true,"shares":22500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares vest on the first anniversary of the Grant Date, provided that the Option will in any case be fully vested on the date of Company's 2023 annual stockholder meeting, subject to the Reporting Person's Continuous Service (as defined in the 2020 Equity Incentive Plan (the \"Plan\")) through such vesting date and will vest in full upon a Change in Control (as defined in the Plan)."}],"balance_after":22500,"derivative":{"exercise_price":1.32,"expiration_date":"2032-05-24","underlying":"Common Stock","underlying_shares":22500},"source":{"system":"sec-edgar","filing":"0001209191-22-032493","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000120919122032493/doc4.xml","form_type":"4"}},{"id":2700955,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2021-05-22T01:10:49.000Z","date":"2021-05-20","kind":"grant","acquired":true,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The shares vest on the first anniversary of the Grant Date, provided that the Option will in any case be fully vested on the date of Company's 2022 annual stockholder meeting, subject to the Reporting Person's Continuous Service (as defined in the 2020 Equity Incentive Plan (the \"Plan\")) through such vesting date and will vest in full upon a Change in Control (as defined in the Plan)."}],"balance_after":10000,"derivative":{"exercise_price":15.24,"expiration_date":"2031-05-19","underlying":"Common Stock","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001209191-21-035151","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000120919121035151/doc4.xml","form_type":"4"}},{"id":2700954,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2021-05-22T01:10:49.000Z","date":"2021-05-20","kind":"exercise","acquired":false,"shares":334,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the stock option vest over a four-year period commencing October 19, 2017, with 1/4th of the shares vesting on October 19, 2018 and 1/36th of the remaining shares vesting on a monthly basis."}],"balance_after":1673,"derivative":{"exercise_price":0.85,"expiration_date":"2027-10-18","underlying":"Common Stock","underlying_shares":2007},"source":{"system":"sec-edgar","filing":"0001209191-21-035151","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000120919121035151/doc4.xml","form_type":"4"}},{"id":2700953,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2021-05-22T01:10:49.000Z","date":"2021-05-20","kind":"sale","acquired":false,"shares":334,"price":15.29,"value":5106.86,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001209191-21-035151","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000120919121035151/doc4.xml","form_type":"4"}},{"id":2700952,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2021-05-22T01:10:49.000Z","date":"2021-05-20","kind":"exercise","acquired":true,"shares":334,"price":0.85,"value":283.9,"ownership":{"direct":true},"balance_after":334,"source":{"system":"sec-edgar","filing":"0001209191-21-035151","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000120919121035151/doc4.xml","form_type":"4"}},{"id":2730238,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2021-05-05T01:09:00.000Z","date":"2021-04-30","kind":"exercise","acquired":false,"shares":14045,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The shares subject to the stock option vest over a four-year period commencing October 19, 2017, with 1/4th of the shares vesting on October 19, 2018 and 1/36th of the remaining shares vesting on a monthly basis."}],"balance_after":2007,"derivative":{"exercise_price":0.85,"expiration_date":"2027-10-18","underlying":"Common Stock","underlying_shares":16052},"source":{"system":"sec-edgar","filing":"0001209191-21-030171","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000120919121030171/doc4.xml","form_type":"4"}},{"id":2730237,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2021-05-05T01:09:00.000Z","date":"2021-04-30","kind":"sale","acquired":false,"shares":14045,"price":16.1384,"value":226663.828,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan previously adopted by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"Represents a weighted-average sales price per share.  These shares were sold in multiple transactions at prices ranging from $15.64 to $17.09. The Reporting Person has provided to the issuer, and undertakes to provide to the staff of the Securities and Exchange Commission or any security holder of the issuer, upon request, full information regarding the number of shares sold at each separate price within the range."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001209191-21-030171","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000120919121030171/doc4.xml","form_type":"4"}},{"id":2730236,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":44226,"kind":"person","name":"SIMPSON CAMILLA V","position":1,"cik":"0001822557","reported_name":"SIMPSON CAMILLA V","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2021-05-05T01:09:00.000Z","date":"2021-04-30","kind":"exercise","acquired":true,"shares":14045,"price":0.85,"value":11938.25,"ownership":{"direct":true},"balance_after":14045,"source":{"system":"sec-edgar","filing":"0001209191-21-030171","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000120919121030171/doc4.xml","form_type":"4"}}]}