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Each RSU represents a contingent right to receive one share of the Issuer's Common Stock. The RSUs will vest in full on the earlier of the first anniversary of the date of grant or the 2027 annual stockholder meeting, subject to the Reporting Person's continuous service through such vesting date."}],"balance_after":35500,"source":{"system":"sec-edgar","filing":"0001628280-26-041268","document":"wk-form4_1780691316.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1576885/000162828026041268/wk-form4_1780691316.xml","form_type":"4"}},{"id":754089,"issuer":{"id":5224,"kind":"organization","name":"Shattuck Labs, Inc."},"owners":[{"id":40806,"kind":"person","name":"Golumbeski George","position":1,"cik":"0001586660","reported_name":"Golumbeski George","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2026-06-03T00:00:09.000Z","date":"2026-05-29","kind":"grant","planned":false,"acquired":true,"shares":81000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option represents the right to purchase a total of 81,000 shares of the Issuer's common stock, which will vest in full on the earlier of the one-year anniversary of the grant date or immediately prior to the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer."}],"balance_after":81000,"derivative":{"exercise_price":5.95,"expiration_date":"2036-05-29","underlying":"Common Stock","underlying_shares":81000},"source":{"system":"sec-edgar","filing":"0001193125-26-254126","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586660/000119312526254126/ownership.xml","form_type":"4"}},{"id":979206,"issuer":{"id":72153,"kind":"organization","name":"Mural Oncology plc","symbol":"MURA"},"owners":[{"id":40806,"kind":"person","name":"Golumbeski George","position":1,"cik":"0001586660","reported_name":"Golumbeski George","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2025-12-05T08:58:35.000Z","date":"2025-12-05","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":15334,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"Pursuant to the terms of the Agreement, at the Effective Time each option to purchase ordinary shares of Issuer that had an exercise price per share that was equal to or greater than the Scheme Consideration was cancelled and ceased to be outstanding, and no Scheme Consideration was delivered in exchange for such options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"Pursuant to the terms of the Agreement, at the Effective Time each option to purchase ordinary shares of Issuer that had an exercise price per share that was equal to or greater than the Scheme Consideration was cancelled and ceased to be outstanding, and no Scheme Consideration was delivered in exchange for such options."}],"balance_after":0,"derivative":{"exercise_price":3.38,"expiration_date":"2034-07-29","underlying":"Ordinary Shares","underlying_shares":15334},"source":{"system":"sec-edgar","filing":"0001193125-25-308770","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1971543/000119312525308770/ownership.xml","form_type":"4"}},{"id":979205,"issuer":{"id":72153,"kind":"organization","name":"Mural Oncology plc","symbol":"MURA"},"owners":[{"id":40806,"kind":"person","name":"Golumbeski George","position":1,"cik":"0001586660","reported_name":"Golumbeski George","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2025-12-05T08:58:35.000Z","date":"2025-12-05","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":8637,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"Pursuant to the terms of the Agreement, at the Effective Time each option to purchase ordinary shares of Issuer that had an exercise price per share that was equal to or greater than the Scheme Consideration was cancelled and ceased to be outstanding, and no Scheme Consideration was delivered in exchange for such options."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Transaction Agreement (the \"Agreement\"), dated August 20, 2025, by and among the Issuer, XRA 5 Corp. (\"Sub\"), a Delaware corporation and wholly-owned subsidiary of XOMA Royalty Corporation, a Nevada corporation, pursuant to which Sub acquired all the issued and to be issued share capital of the Issuer (the \"Acquisition\") for a cash purchase price of $2.035 per share (the \"Scheme Consideration\"). The Acquisition was completed as of December 5, 2025 (the \"Effective Time\")."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"Pursuant to the terms of the Agreement, at the Effective Time each option to purchase ordinary shares of Issuer that had an exercise price per share that was equal to or greater than the Scheme Consideration was cancelled and ceased to be outstanding, and no Scheme Consideration was delivered in exchange for such options."}],"balance_after":0,"derivative":{"exercise_price":2.56,"expiration_date":"2035-06-10","underlying":"Ordinary Shares","underlying_shares":8637},"source":{"system":"sec-edgar","filing":"0001193125-25-308770","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1971543/000119312525308770/ownership.xml","form_type":"4"}},{"id":1003438,"issuer":{"id":6281,"kind":"organization","name":"Acumen Pharmaceuticals, Inc."},"owners":[{"id":40806,"kind":"person","name":"Golumbeski George","position":1,"cik":"0001586660","reported_name":"Golumbeski George","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2025-11-10T21:49:06.000Z","date":"2025-11-06","kind":"grant","planned":false,"acquired":true,"shares":50000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option will vest in equal monthly installments over a three-year period such that the option is fully vested on the third anniversary of the date of grant, subject to the Reporting Person's continuous service through each such vesting date and shall vest and become immediately exercisable prior to the effectiveness of a change in control."}],"balance_after":50000,"derivative":{"exercise_price":1.9,"expiration_date":"2035-11-06","underlying":"Common Stock","underlying_shares":50000},"source":{"system":"sec-edgar","filing":"0001586660-25-000003","document":"wk-form4_1762811342.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1576885/000158666025000003/wk-form4_1762811342.xml","form_type":"4"}},{"id":1078150,"issuer":{"id":77038,"kind":"organization","name":"Sage Therapeutics, Inc.","symbol":"SAGE"},"owners":[{"id":40806,"kind":"person","name":"Golumbeski George","position":1,"cik":"0001586660","reported_name":"Golumbeski George","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-07-31T15:42:16.000Z","date":"2025-07-31","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":21500,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"Pursuant to the Merger Agreement, at the Effective Time, each option to purchase Shares (a \"Company Option\") then outstanding and unexercised, whether or not vested, which had a per Share exercise price less than the Closing Amount was deemed fully vested and cancelled and converted into the right to receive (i) a cash payment (without interest and subject to the withholding of applicable taxes) equal to the product of (a) the excess of the Closing Amount over the per Share exercise price of such Company Option, multiplied by (b) the total number of Shares subject to such Company Option immediately prior to the Effective Time, plus (ii) one CVR for each Share subject to such Company Option immediately prior to the Effective Time. Each Company Option, whether or not vested, which had a per Share exercise price greater than or equal to the Closing Amount was cancelled with no consideration payable in respect thereof."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"Pursuant to the Merger Agreement, at the Effective Time, each option to purchase Shares (a \"Company Option\") then outstanding and unexercised, whether or not vested, which had a per Share exercise price less than the Closing Amount was deemed fully vested and cancelled and converted into the right to receive (i) a cash payment (without interest and subject to the withholding of applicable taxes) equal to the product of (a) the excess of the Closing Amount over the per Share exercise price of such Company Option, multiplied by (b) the total number of Shares subject to such Company Option immediately prior to the Effective Time, plus (ii) one CVR for each Share subject to such Company Option immediately prior to the Effective Time. Each Company Option, whether or not vested, which had a per Share exercise price greater than or equal to the Closing Amount was cancelled with no consideration payable in respect thereof."}],"balance_after":0,"derivative":{"exercise_price":6.77,"expiration_date":"2035-06-10","underlying":"Common Stock","underlying_shares":21500},"source":{"system":"sec-edgar","filing":"0000950170-25-100666","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1586660/000095017025100666/ownership.xml","form_type":"4"}},{"id":1078149,"issuer":{"id":77038,"kind":"organization","name":"Sage Therapeutics, Inc.","symbol":"SAGE"},"owners":[{"id":40806,"kind":"person","name":"Golumbeski George","position":1,"cik":"0001586660","reported_name":"Golumbeski George","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-07-31T15:42:16.000Z","date":"2025-07-31","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":13593,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"Pursuant to the Merger Agreement, at the Effective Time, each option to purchase Shares (a \"Company Option\") then outstanding and unexercised, whether or not vested, which had a per Share exercise price less than the Closing Amount was deemed fully vested and cancelled and converted into the right to receive (i) a cash payment (without interest and subject to the withholding of applicable taxes) equal to the product of (a) the excess of the Closing Amount over the per Share exercise price of such Company Option, multiplied by (b) the total number of Shares subject to such Company Option immediately prior to the Effective Time, plus (ii) one CVR for each Share subject to such Company Option immediately prior to the Effective Time. Each Company Option, whether or not vested, which had a per Share exercise price greater than or equal to the Closing Amount was cancelled with no consideration payable in respect thereof."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"Pursuant to the Merger Agreement, at the Effective Time, each option to purchase Shares (a \"Company Option\") then outstanding and unexercised, whether or not vested, which had a per Share exercise price less than the Closing Amount was deemed fully vested and cancelled and converted into the right to receive (i) a cash payment (without interest and subject to the withholding of applicable taxes) equal to the product of (a) the excess of the Closing Amount over the per Share exercise price of such Company Option, multiplied by (b) the total number of Shares subject to such Company Option immediately prior to the Effective Time, plus (ii) one CVR for each Share subject to such Company Option immediately prior to the Effective Time. Each Company Option, whether or not vested, which had a per Share exercise price greater than or equal to the Closing Amount was cancelled with no consideration payable in respect thereof."}],"balance_after":0,"derivative":{"exercise_price":6.14,"expiration_date":"2035-01-03","underlying":"Common Stock","underlying_shares":13593},"source":{"system":"sec-edgar","filing":"0000950170-25-100666","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1586660/000095017025100666/ownership.xml","form_type":"4"}},{"id":1078148,"issuer":{"id":77038,"kind":"organization","name":"Sage Therapeutics, Inc.","symbol":"SAGE"},"owners":[{"id":40806,"kind":"person","name":"Golumbeski George","position":1,"cik":"0001586660","reported_name":"Golumbeski George","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2025-07-31T15:42:16.000Z","date":"2025-07-31","kind":"other","planned":false,"acquired":false,"shares":8000,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the \"Merger Agreement\"), dated as of June 13, 2025, among Sage Therapeutics, Inc. (the \"Issuer\"), Supernus Pharmaceuticals, Inc. (\"Parent\"), and Saphire, Inc., a wholly owned subsidiary of Parent (\"Purchaser\"), pursuant to which Purchaser completed a cash tender offer for shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer, effective as of July 31, 2025 (the effective time of the merger, the \"Effective Time\"). At the Effective Time, each issued and outstanding Share was cancelled and converted into the right to receive (i) $8.50 per Share in cash (the \"Closing Amount\"), plus (ii) one contingent value right (\"CVR\") per Share, each without interest and subject to the withholding of applicable taxes."},{"field":"kind","element":"transactionCoding","label":"F2","text":"(Continued from footnote 1) Each CVR represents the right to receive up to $3.50 per Share in cash upon the satisfaction of specified milestones, as described in the Form 8-K filed by the Issuer with the Securities and Exchange Commission on June 16, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the \"Merger Agreement\"), dated as of June 13, 2025, among Sage Therapeutics, Inc. (the \"Issuer\"), Supernus Pharmaceuticals, Inc. (\"Parent\"), and Saphire, Inc., a wholly owned subsidiary of Parent (\"Purchaser\"), pursuant to which Purchaser completed a cash tender offer for shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer, effective as of July 31, 2025 (the effective time of the merger, the \"Effective Time\"). At the Effective Time, each issued and outstanding Share was cancelled and converted into the right to receive (i) $8.50 per Share in cash (the \"Closing Amount\"), plus (ii) one contingent value right (\"CVR\") per Share, each without interest and subject to the withholding of applicable taxes."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"(Continued from footnote 1) Each CVR represents the right to receive up to $3.50 per Share in cash upon the satisfaction of specified milestones, as described in the Form 8-K filed by the Issuer with the Securities and Exchange Commission on June 16, 2025."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0000950170-25-100666","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586660/000095017025100666/ownership.xml","form_type":"4"}},{"id":1086355,"issuer":{"id":5224,"kind":"organization","name":"Shattuck Labs, Inc."},"owners":[{"id":40806,"kind":"person","name":"Golumbeski George","position":1,"cik":"0001586660","reported_name":"Golumbeski George","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-07-16T20:21:25.000Z","date":"2025-07-14","kind":"grant","planned":false,"acquired":true,"shares":33150,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option represents the right to purchase a total of 33,150 shares of the Issuer's common stock, which will vest in full on the earlier of the one-year anniversary of the grant date or immediately prior to the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service to the Issuer."}],"balance_after":33150,"derivative":{"exercise_price":0.82,"expiration_date":"2035-07-14","underlying":"Common Stock","underlying_shares":33150},"source":{"system":"sec-edgar","filing":"0000950170-25-096275","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586660/000095017025096275/ownership.xml","form_type":"4"}},{"id":1111024,"issuer":{"id":77038,"kind":"organization","name":"Sage Therapeutics, Inc.","symbol":"SAGE"},"owners":[{"id":40806,"kind":"person","name":"Golumbeski George","position":1,"cik":"0001586660","reported_name":"Golumbeski George","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-06-13T20:14:04.000Z","date":"2025-06-11","kind":"grant","planned":false,"acquired":true,"shares":21500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The stock option award was issued pursuant to the Sage Therapeutics, Inc. 2024 Equity Incentive Plan in accordance with Sage's Non-Employee Director Compensation Program. The option will vest in full upon the earlier to occur of June 11, 2026 or the day immediately prior to the 2026 Annual Meeting of Sage's stockholders, subject to continued service as a director on such date."}],"balance_after":21500,"derivative":{"exercise_price":6.77,"expiration_date":"2035-06-11","underlying":"Common Stock","underlying_shares":21500},"source":{"system":"sec-edgar","filing":"0001562180-25-004793","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586660/000156218025004793/primarydocument.xml","form_type":"4"}},{"id":1112082,"issuer":{"id":72153,"kind":"organization","name":"Mural Oncology plc","symbol":"MURA"},"owners":[{"id":40806,"kind":"person","name":"Golumbeski George","position":1,"cik":"0001586660","reported_name":"Golumbeski George","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2025-06-13T08:00:05.000Z","date":"2025-06-11","kind":"grant","planned":false,"acquired":true,"shares":8637,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on June 11, 2025. This option will vest in full upon the earlier of (i) the first anniversary of the date of the grant or (ii) the date of the next Annual Meeting, subject to the reporting person's continued service with the Issuer."}],"balance_after":8637,"derivative":{"exercise_price":2.56,"expiration_date":"2035-06-10","underlying":"Ordinary Shares","underlying_shares":8637},"source":{"system":"sec-edgar","filing":"0000950170-25-085818","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1971543/000095017025085818/ownership.xml","form_type":"4"}},{"id":1309733,"issuer":{"id":77038,"kind":"organization","name":"Sage Therapeutics, Inc.","symbol":"SAGE"},"owners":[{"id":40806,"kind":"person","name":"Golumbeski George","position":1,"cik":"0001586660","reported_name":"Golumbeski George","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Options (Right to buy)","published_at":"2025-01-06T21:02:52.000Z","date":"2025-01-03","kind":"grant","planned":false,"acquired":true,"shares":13593,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The reporting person elected to receive this stock option award in lieu of payment of all cash retainers that would otherwise be paid for the reporting person's service during 2025 on the issuer's board or its committees, as permitted under the issuer's non-employee director compensation program. The stock option is granted under and subject to the terms of the Sage Therapeutics, Inc. 2024 Equity Incentive Plan. 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