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These shares were sold in multiple transactions at prices ranging from $524.51 to $525.49, inclusive."}],"balance_after":194222,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":14,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940276,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"sale","planned":true,"acquired":false,"shares":1199,"price":524.0986,"value":628394.2214,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F13","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $523.51 to $524.48, inclusive."}],"balance_after":196654,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":13,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940275,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"sale","planned":true,"acquired":false,"shares":970,"price":522.9972,"value":507307.284,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F12","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $522.49 to $523.46, inclusive."}],"balance_after":197853,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":12,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940274,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"sale","planned":true,"acquired":false,"shares":840,"price":521.9779,"value":438461.436,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F11","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $521.49 to $522.40, inclusive."}],"balance_after":198823,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":11,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940273,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"sale","planned":true,"acquired":false,"shares":681,"price":521.0327,"value":354823.2687,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F10","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $520.48 to $521.45, inclusive."}],"balance_after":199663,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":10,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940272,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"sale","planned":true,"acquired":false,"shares":846,"price":519.8838,"value":439821.6948,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F9","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $519.45 to $520.42, inclusive."}],"balance_after":200344,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":9,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940271,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"sale","planned":true,"acquired":false,"shares":1363,"price":518.6837,"value":706965.8831,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F8","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $518.38 to $519.37, inclusive."}],"balance_after":201190,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940270,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"sale","planned":true,"acquired":false,"shares":2450,"price":517.8591,"value":1268754.795,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F7","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $517.36 to $518.35, inclusive."}],"balance_after":202553,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940269,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"sale","planned":true,"acquired":false,"shares":766,"price":516.8356,"value":395896.0696,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F6","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $516.34 to $517.28, inclusive."}],"balance_after":205003,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940268,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"sale","planned":true,"acquired":false,"shares":1996,"price":515.8123,"value":1029561.3508,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F5","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $515.29 to $516.21, inclusive."}],"balance_after":205769,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940267,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"sale","planned":true,"acquired":false,"shares":1345,"price":514.681,"value":692245.945,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $514.28 to $515.22, inclusive."}],"balance_after":207765,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940266,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"sale","planned":true,"acquired":false,"shares":1094,"price":513.1079,"value":561340.0426,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $512.77 to $513.60, inclusive."}],"balance_after":209110,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940265,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"sale","planned":true,"acquired":false,"shares":1480,"price":511.9774,"value":757726.552,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $511.71 to $512.51, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote and the footnotes below."}],"balance_after":210204,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":940264,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-01-13T21:43:08.000Z","date":"2026-01-09","kind":"exercise","planned":true,"acquired":true,"shares":24520,"price":15.8,"value":387416.0,"ownership":{"direct":true},"balance_after":211684,"source":{"system":"sec-edgar","filing":"0001628280-26-001976","document":"wk-form4_1768340585.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828026001976/wk-form4_1768340585.xml","form_type":"4"}},{"id":971639,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-12-12T21:40:31.000Z","date":"2025-12-10","kind":"exercise","planned":true,"acquired":false,"shares":24800,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F11","text":"The shares underlying this stock option are fully vested and exercisable."}],"balance_after":24800,"derivative":{"exercise_price":15.8,"expiration_date":"2027-03-02","underlying":"Common Stock","underlying_shares":24800},"source":{"system":"sec-edgar","filing":"0001628280-25-056794","document":"wk-form4_1765575628.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":12,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828025056794/wk-form4_1765575628.xml","form_type":"4"}},{"id":971638,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2025-12-12T21:40:31.000Z","date":"2025-12-10","kind":"sale","planned":true,"acquired":false,"shares":160,"price":555.39,"value":88862.4,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."}],"balance_after":187164,"source":{"system":"sec-edgar","filing":"0001628280-25-056794","document":"wk-form4_1765575628.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":10,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828025056794/wk-form4_1765575628.xml","form_type":"4"}},{"id":971637,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2025-12-12T21:40:31.000Z","date":"2025-12-10","kind":"sale","planned":true,"acquired":false,"shares":1029,"price":554.9963,"value":571091.1927,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F9","text":"The price reported in Column 4 is a weighted average price. 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These shares were sold in multiple transactions at prices ranging from $549.27 to $550.23, inclusive."}],"balance_after":210396,"source":{"system":"sec-edgar","filing":"0001628280-25-056794","document":"wk-form4_1765575628.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828025056794/wk-form4_1765575628.xml","form_type":"4"}},{"id":971631,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2025-12-12T21:40:31.000Z","date":"2025-12-10","kind":"sale","planned":true,"acquired":false,"shares":535,"price":548.5067,"value":293451.0845,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $548.17 to $549.08, inclusive."}],"balance_after":210805,"source":{"system":"sec-edgar","filing":"0001628280-25-056794","document":"wk-form4_1765575628.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828025056794/wk-form4_1765575628.xml","form_type":"4"}},{"id":971630,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2025-12-12T21:40:31.000Z","date":"2025-12-10","kind":"sale","planned":true,"acquired":false,"shares":624,"price":547.7462,"value":341793.6288,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on September 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $547.17 to $548.13, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote and the footnotes below."}],"balance_after":211340,"source":{"system":"sec-edgar","filing":"0001628280-25-056794","document":"wk-form4_1765575628.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828025056794/wk-form4_1765575628.xml","form_type":"4"}},{"id":971629,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2025-12-12T21:40:31.000Z","date":"2025-12-10","kind":"exercise","planned":true,"acquired":true,"shares":24800,"price":15.8,"value":391840.0,"ownership":{"direct":true},"balance_after":211964,"source":{"system":"sec-edgar","filing":"0001628280-25-056794","document":"wk-form4_1765575628.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000162828025056794/wk-form4_1765575628.xml","form_type":"4"}},{"id":1068107,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-08-13T22:18:57.000Z","date":"2025-08-13","kind":"exercise","planned":true,"acquired":false,"shares":129172,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F20","text":"The shares underlying this stock option are fully vested and exercisable."}],"balance_after":0,"derivative":{"exercise_price":9.45,"expiration_date":"2026-07-22","underlying":"Common Stock","underlying_shares":129172},"source":{"system":"sec-edgar","filing":"0001236927-25-000007","document":"wk-form4_1755123534.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":20,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000123692725000007/wk-form4_1755123534.xml","form_type":"4"}},{"id":1068106,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2025-08-13T22:18:57.000Z","date":"2025-08-13","kind":"sale","planned":true,"acquired":false,"shares":4155,"price":374.3835,"value":1555563.4425,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 14, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F18","text":"The price reported in Column 4 is a weighted average price. 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These shares were sold in multiple transactions at prices ranging from $369.90 to $370.88, inclusive."}],"balance_after":267171,"source":{"system":"sec-edgar","filing":"0001236927-25-000007","document":"wk-form4_1755123534.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":14,"url":"https://www.sec.gov/Archives/edgar/data/1157601/000123692725000007/wk-form4_1755123534.xml","form_type":"4"}},{"id":1068101,"issuer":{"id":3441,"kind":"organization","name":"MADRIGAL PHARMACEUTICALS, INC.","symbol":"MDGL"},"owners":[{"id":39620,"kind":"person","name":"FRIEDMAN PAUL A","position":1,"cik":"0001236927","reported_name":"FRIEDMAN PAUL A","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2025-08-13T22:18:57.000Z","date":"2025-08-13","kind":"sale","planned":true,"acquired":false,"shares":7992,"price":369.4388,"value":2952554.8896,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"These sales were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on March 14, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F13","text":"The price reported in Column 4 is a weighted average price. 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