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The issuance of such securities was approved by the Issuer's board of directors in accordance with Rule 16 (b)-3 of the Securities Exchange Act of 1934, as amended."}],"balance_after":55393,"source":{"system":"sec-edgar","filing":"0001437749-26-030729","document":"rdgdoc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1835330/000143774926030729/rdgdoc.xml","form_type":"4"}},{"id":737335,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"stock option","published_at":"2026-06-15T18:23:25.000Z","date":"2026-06-11","kind":"grant","planned":false,"acquired":true,"shares":65000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on June 11, 2026 as an option for 65,000 shares of Common Stock under the Clene Inc Amended 2020 Stock Plan at an exercise price of $5.53 per share.  The options vest with respect to the first 25% of such shares on June 11, 2027 and then in 36 equal installments of the balance of the shares of Common Stock on the 11th day of each month beginning July 11, 2027 until such share are fully vested."}],"balance_after":65000,"derivative":{"exercise_price":5.53,"expiration_date":"2036-06-10","underlying":"common stock","underlying_shares":65000},"source":{"system":"sec-edgar","filing":"0001437749-26-020636","document":"rdgdoc.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000143774926020636/rdgdoc.xml","form_type":"4"}},{"id":931897,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"stock option","published_at":"2026-01-23T21:12:12.000Z","date":"2026-01-22","kind":"grant","planned":false,"acquired":true,"shares":75000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on January 22, 2026 as an option for 75,000 shares of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $5.42 per share. The options vest immediately upon grant."}],"balance_after":75000,"derivative":{"exercise_price":5.42,"expiration_date":"2036-01-21","underlying":"common stock","underlying_shares":75000},"source":{"system":"sec-edgar","filing":"0001437749-26-001910","document":"rdgdoc.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000143774926001910/rdgdoc.xml","form_type":"4"}},{"id":1030318,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"stock option","published_at":"2025-09-30T19:56:26.000Z","date":"2025-09-25","kind":"grant","planned":false,"acquired":true,"shares":40000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"This Form 4 amendment is being filed to correct a Form 4 filed on September 29, 2025.  The corrected exercise price is $5.88 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This option was granted on September 25, 2025 as an option for 40,000 shares of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $5.88 per share. The options vest in 12 equal monthly installments on the 25th day of each calendar month, beginning October 25, 2025, until such shares are fully vested."}],"balance_after":40000,"derivative":{"exercise_price":5.88,"expiration_date":"2035-09-24","underlying":"common stock","underlying_shares":40000},"source":{"system":"sec-edgar","filing":"0001437749-25-030107","document":"rdgdoc.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000143774925030107/rdgdoc.xml","form_type":"4/A","original_submission_date":"2025-09-29"}},{"id":1031058,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"stock option","published_at":"2025-09-29T20:11:44.000Z","date":"2025-09-25","kind":"grant","planned":false,"acquired":true,"shares":40000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on September 25, 2025 as an option for 40,000 shares of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $6.05 per share. The options vest in 12 equal monthly installments on the 25th day of each calendar month, beginning October 25, 2025, until such shares are fully vested."}],"balance_after":40000,"derivative":{"exercise_price":6.05,"expiration_date":"2035-09-24","underlying":"common stock","underlying_shares":40000},"source":{"system":"sec-edgar","filing":"0001437749-25-030016","document":"rdgdoc.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000143774925030016/rdgdoc.xml","form_type":"4"}},{"id":1035301,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"officer_title":"President & CEO"}}],"security":"stock option","published_at":"2025-09-19T19:54:13.000Z","date":"2025-09-18","kind":"grant","planned":false,"acquired":true,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on September 18, 2025 as an option for 10,000 share of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $6.32 per share. The options vest immediately upon grant."}],"balance_after":10000,"derivative":{"exercise_price":6.32,"expiration_date":"2035-09-17","underlying":"common stock","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001437749-25-029480","document":"rdgdoc.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000143774925029480/rdgdoc.xml","form_type":"4"}},{"id":1245105,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Options (Right to buy)","published_at":"2025-02-25T21:11:27.000Z","date":"2025-02-24","kind":"grant","planned":false,"acquired":true,"shares":45000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on February 24, 2025 as an option for 45,000 shares of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $4.23 per share. The options vest with respect to the first 25% of such shares on February 24, 2026 and then in 36 equal installments of the balance of the shares of Common Stock on the 24th day of each calendar month thereafter beginning March 24, 2026 until such shares are fully vested."}],"balance_after":45000,"derivative":{"exercise_price":4.23,"expiration_date":"2035-02-23","underlying":"Common Stock","underlying_shares":45000},"source":{"system":"sec-edgar","filing":"0001562180-25-001592","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218025001592/primarydocument.xml","form_type":"4"}},{"id":1396469,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Warrants (Right to buy)","published_at":"2024-10-01T20:17:06.000Z","date":"2024-09-30","kind":"grant","planned":false,"acquired":true,"shares":10000,"price":0.125,"value":1250.0,"ownership":{"direct":true},"balance_after":10000,"derivative":{"exercise_price":4.82,"exercise_date":"2024-10-01","expiration_date":"2029-10-01","underlying":"Common Stock","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001562180-24-007036","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218024007036/primarydocument.xml","form_type":"4"}},{"id":1396468,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2024-10-01T20:17:06.000Z","date":"2024-09-30","kind":"purchase","planned":false,"acquired":true,"shares":10000,"price":4.75,"value":47500.0,"ownership":{"direct":true},"balance_after":40149,"source":{"system":"sec-edgar","filing":"0001562180-24-007036","document":"primarydocument.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218024007036/primarydocument.xml","form_type":"4"}},{"id":1428665,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Options (Right to buy)","published_at":"2024-08-19T20:15:02.000Z","date":"2024-08-16","kind":"grant","planned":false,"acquired":true,"shares":25000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on August 16, 2024 as an option for 25,000 shares of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $5.15 per share. The options vest with respect to 1/12th of such shares on September 16, 2024 and then an additional 1/12th of such options vest on the 16th day of each calendar month thereafter until such shares are fully vested."}],"balance_after":25000,"derivative":{"exercise_price":5.15,"expiration_date":"2034-08-15","underlying":"Common Stock","underlying_shares":25000},"source":{"system":"sec-edgar","filing":"0001562180-24-006354","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218024006354/primarydocument.xml","form_type":"4"}},{"id":1445996,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Options (Right to buy)","published_at":"2024-07-30T13:03:54.000Z","date":"2024-07-29","kind":"exercise","planned":false,"acquired":true,"shares":27320,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F6","text":"On July 11, 2024, the common stock of Clene Inc. underwent a 1-for-20 reverse stock split, resulting in the reporting person's stock option grant of 1,092,777 options to purchase common stock being reduced to 54,639 options.  The exercise option price for these options was increased from $0.15 per share to $3.00 per share."},{"field":"shares","element":"transactionShares","label":"F6","text":"On July 11, 2024, the common stock of Clene Inc. underwent a 1-for-20 reverse stock split, resulting in the reporting person's stock option grant of 1,092,777 options to purchase common stock being reduced to 54,639 options.  The exercise option price for these options was increased from $0.15 per share to $3.00 per share."}],"balance_after":27319,"derivative":{"exercise_price":3,"exercise_date":"2014-07-31","expiration_date":"2024-07-30","underlying":"Common Stock","underlying_shares":27320},"source":{"system":"sec-edgar","filing":"0001562180-24-005867","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218024005867/primarydocument.xml","form_type":"4"}},{"id":1445995,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2024-07-30T13:03:54.000Z","date":"2024-07-29","kind":"exercise","planned":false,"acquired":true,"shares":27320,"price":3,"value":81960.0,"ownership":{"direct":true},"footnotes":[{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"On July 11, 2024, the common stock of Clene Inc. underwent a 1-for-20 reverse stock split, resulting in the reporting person's ownership in the previously disclosed 56,593 shares of common stock being reduced to 2,829 shares."}],"balance_after":30149,"source":{"system":"sec-edgar","filing":"0001562180-24-005867","document":"primarydocument.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218024005867/primarydocument.xml","form_type":"4"}},{"id":1484362,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Options (Right to buy)","published_at":"2024-06-10T20:17:06.000Z","date":"2024-06-07","kind":"grant","planned":false,"acquired":true,"shares":2250000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This option was granted on June 7, 2024 as an option for 2,250,000 shares of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $0.37 per share. The options vest with respect to the first 33.3% of such shares if Clene Inc. has an NDA accepted by the FDA, an additional 33.3% of such shares if Clene Inc. has an NDA approved by the FDA, and the remaining 33.4% of such shares if Clene Inc. achieves $100,000,000 in revenues in connection with the sales of any approved drugs."}],"balance_after":2250000,"derivative":{"exercise_price":0.37,"expiration_date":"2034-06-06","underlying":"Common Stock","underlying_shares":2250000},"source":{"system":"sec-edgar","filing":"0001562180-24-004897","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218024004897/primarydocument.xml","form_type":"4"}},{"id":1484361,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Options (Right to buy)","published_at":"2024-06-10T20:17:06.000Z","date":"2024-06-07","kind":"grant","planned":false,"acquired":true,"shares":900000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on June 7, 2024 as an option for 900,000 shares of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $0.37 per share. The options vest with respect to the first 25% of such shares on June 7, 2025 and then in 36 equal installments of Common Stock on the 7th day of each calendar month, beginning July 7, 2025, until such shares are fully vested"}],"balance_after":900000,"derivative":{"exercise_price":0.37,"expiration_date":"2034-06-06","underlying":"Common Stock","underlying_shares":900000},"source":{"system":"sec-edgar","filing":"0001562180-24-004897","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218024004897/primarydocument.xml","form_type":"4"}},{"id":1839208,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Options (Right to buy)","published_at":"2023-07-03T17:49:59.000Z","date":"2023-06-29","kind":"grant","planned":false,"acquired":true,"shares":900000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on June 29, 2023 as an option for 900,000 shares of Common Stock under the Clene Inc. Amended 2020 Stock Plan at an exercise price of $0.90 per share. The options vest with respect to the first 25% of such shares on June 29, 2024 and then in 36 equal installments of the balance of the shares of Common Stock on the last day of each calendar month beginning July 29, 2024 until such shares are fully vested. If Clene Inc. has an NDA accepted by the FDA, 50% of the option shares shall vest on that date. If the FDA approves the  accepted NDA, the then remaining unvested option shares shall vest on that date."}],"balance_after":900000,"derivative":{"exercise_price":0.9,"expiration_date":"2033-06-29","underlying":"Common Stock","underlying_shares":900000},"source":{"system":"sec-edgar","filing":"0001562180-23-005629","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218023005629/primarydocument.xml","form_type":"4"}},{"id":1843210,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2023-06-27T12:07:48.000Z","date":"2023-06-26","kind":"purchase","planned":false,"acquired":true,"shares":25000,"price":0.81,"value":20250.0,"ownership":{"direct":false,"nature":"By Trust"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Etherington Revocable Trust purchased 25,000 shares of common stock of Clene Inc. in multiple transactions on June 26, 2023 at prices ranging from $0.80 to $0.82, inclusive, for a weighted average price of $0.81 per share."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are owned by the Etherington Revocable Trust.  Mr. Etherington is the co-trustee of the Etherington Revocable Trust.  The shares owned by the Etherington Revocable Trust may be deemed to be beneficially owned by Mr. Etherington."}],"balance_after":25000,"source":{"system":"sec-edgar","filing":"0001562180-23-005506","document":"primarydocument.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218023005506/primarydocument.xml","form_type":"4"}},{"id":2123164,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Options (Right to buy)","published_at":"2022-11-07T22:14:04.000Z","date":"2022-11-04","kind":"grant","acquired":true,"shares":400000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on November 4, 2022 as an option for 400,000 shares of Common Stock under the Clene Inc. 2020 Stock Plan at an exercise price of $1.11 per share. The options vest with respect to the first 25% of such shares on November 4, 2023 and then in 36 equal installments of the balance of the shares of Common Stock on the 4th day of each calendar month thereafter beginning December 4, 2023 until such shares are fully vested."}],"balance_after":400000,"derivative":{"exercise_price":1.11,"expiration_date":"2032-11-04","underlying":"Common Stock","underlying_shares":400000},"source":{"system":"sec-edgar","filing":"0001562180-22-007530","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218022007530/primarydocument.xml","form_type":"4"}},{"id":2204964,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2022-07-19T20:08:31.000Z","date":"2022-07-18","kind":"sale","acquired":false,"shares":23483,"price":4.72,"value":110839.76,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The sales reported in this Form 4 represent shares of common stock of Clene Inc. required to be sold by Mr. Etherington to satisfy tax obligations in connection with the vesting of 80,076 restricted stock awards.  The sales occurred automatically to satisfy tax withholding obligations to be funded by a \"sell to cover\" transaction pursuant to a Rule 10b5-1 trading plan at a weighted average price of $4.72; the shares were sold in multiple transactions at prices ranging from $4.36 to $4.94, inclusive."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The sales reported in this Form 4 represent shares of common stock of Clene Inc. required to be sold by Mr. Etherington to satisfy tax obligations in connection with the vesting of 80,076 restricted stock awards.  The sales occurred automatically to satisfy tax withholding obligations to be funded by a \"sell to cover\" transaction pursuant to a Rule 10b5-1 trading plan at a weighted average price of $4.72; the shares were sold in multiple transactions at prices ranging from $4.36 to $4.94, inclusive."}],"balance_after":56593,"source":{"system":"sec-edgar","filing":"0001562180-22-005708","document":"primarydocument.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218022005708/primarydocument.xml","form_type":"4"}},{"id":2391208,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Options (Right to buy)","published_at":"2022-02-16T13:59:27.000Z","date":"2022-02-15","kind":"grant","acquired":true,"shares":480000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This option was granted on February 15, 2022 as an option for 480,000 shares of Common Stock under the Clene Inc. 2020 Stock Plan at an exercise price of $3.04 per share. The options vest  with respect to the first 25% of such shares on February 15, 2023 and then in 36 equal installments of the balance of the shares of Common Stock on the 15th day of each calendar month thereafter beginning March 15, 2023 until such shares are fully vested."}],"balance_after":480000,"derivative":{"exercise_price":3.04,"expiration_date":"2032-02-15","underlying":"Common Stock","underlying_shares":480000},"source":{"system":"sec-edgar","filing":"0001562180-22-001500","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218022001500/primarydocument.xml","form_type":"4"}},{"id":2391207,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Options (Right to buy)","published_at":"2022-02-16T13:59:27.000Z","date":"2022-02-15","kind":"grant","acquired":true,"shares":69652,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on February 15, 2022 as an option for 69,652 shares of Common Stock under the Clene Inc. 2020 Stock Plan at an exercise price of $3.04 per share. The options shall vest immediately upon grant."}],"balance_after":69652,"derivative":{"exercise_price":3.04,"expiration_date":"2032-02-15","underlying":"Common Stock","underlying_shares":69652},"source":{"system":"sec-edgar","filing":"0001562180-22-001500","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218022001500/primarydocument.xml","form_type":"4"}},{"id":2524157,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Options (Right to buy)","published_at":"2021-11-04T22:58:14.000Z","date":"2021-11-04","kind":"grant","acquired":true,"shares":100000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on November 4, 2021 as an option for 100,000 shares of Common Stock under the Clene Inc. 2020 Stock Plan at an exercise price of $4.74 per share. The options vest  with respect to the first 25% of such shares on November 4, 2022 and then in 36 equal installments of Common Stock on the last day of each calendar month, beginning November 30, 2022, until such shares are fully vested"}],"balance_after":100000,"derivative":{"exercise_price":4.74,"expiration_date":"2031-11-04","underlying":"Common Stock","underlying_shares":100000},"source":{"system":"sec-edgar","filing":"0001562180-21-006855","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218021006855/primarydocument.xml","form_type":"4"}},{"id":2647046,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Common Stock","published_at":"2021-07-01T13:19:39.000Z","date":"2021-06-30","kind":"grant","acquired":true,"shares":80076,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This restricted stock award was granted on June 30, 2021 under the Clene Inc. 2020 Stock Plan.  The award fully vests on January 15, 2022."}],"balance_after":80076,"source":{"system":"sec-edgar","filing":"0001562180-21-004605","document":"primarydocument.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218021004605/primarydocument.xml","form_type":"4"}},{"id":2734150,"issuer":{"id":7166,"kind":"organization","name":"Clene Inc.","symbol":"CLNN"},"owners":[{"id":37998,"kind":"person","name":"Etherington Robert Dee","position":1,"cik":"0001835330","reported_name":"Etherington Robert Dee","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Stock Options (Right to buy)","published_at":"2021-04-30T21:22:15.000Z","date":"2021-04-30","kind":"grant","acquired":true,"shares":600000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This option was granted on April 30, 2021 under the Clene Inc. 2020 Stock Plan. The options vest with respect to the first 25% on May 31, 2022 and then in 36 equal installments of 1/48th of the balance on the last day of each calendar month, beginning June 30, 2022, until fully vested"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on April 30, 2021 under the Clene Inc. 2020 Stock Plan. The options vest with respect to the first 25% on May 31, 2022 and then in 36 equal installments of 1/48th of the balance on the last day of each calendar month, beginning June 30, 2022, until fully vested"}],"balance_after":600000,"derivative":{"exercise_price":9,"expiration_date":"2031-04-30","underlying":"Common Stock","underlying_shares":600000},"source":{"system":"sec-edgar","filing":"0001562180-21-003065","document":"primarydocument.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1822791/000156218021003065/primarydocument.xml","form_type":"4"}}]}