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These restricted stock units will vest 100% on May 20, 2027."},{"field":"shares","element":"transactionShares","label":"F1","text":"This grant was made under the 2023 Omnibus Incentive Plan pursuant to the issuer's non-employee director compensation policy."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"Each restricted stock unit represents a contingent right to receive one share of common stock. These restricted stock units will vest 100% on May 20, 2027."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"Each restricted stock unit represents a contingent right to receive one share of common stock. These restricted stock units will vest 100% on May 20, 2027."}],"balance_after":34200,"derivative":{"underlying":"Common Stock","underlying_shares":34200},"source":{"system":"sec-edgar","filing":"0001278219-26-000001","document":"wk-form4_1779394245.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1055726/000127821926000001/wk-form4_1779394245.xml","form_type":"4"}},{"id":768648,"issuer":{"id":6589,"kind":"organization","name":"INOVIO PHARMACEUTICALS, INC."},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock Options","published_at":"2026-05-21T20:10:48.000Z","date":"2026-05-20","kind":"grant","planned":false,"acquired":true,"shares":41800,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This grant was made under the 2023 Omnibus Incentive Plan pursuant to the issuer's non-employee director compensation policy."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"Options to vest 100% on May 20, 2027."}],"balance_after":41800,"derivative":{"exercise_price":1.23,"expiration_date":"2036-05-20","underlying":"Common Stock","underlying_shares":41800},"source":{"system":"sec-edgar","filing":"0001278219-26-000001","document":"wk-form4_1779394245.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1055726/000127821926000001/wk-form4_1779394245.xml","form_type":"4"}},{"id":793348,"issuer":{"id":3952,"kind":"organization","name":"FIRST FINANCIAL BANKSHARES INC","symbol":"FFIN"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-05-05T21:49:38.000Z","date":"2026-04-28","kind":"grant","planned":false,"acquired":true,"shares":2142,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This amount represents a restricted stock grant that vests in a single installment on April 27, 2027."}],"balance_after":2142,"source":{"system":"sec-edgar","filing":"0001193125-26-206910","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/36029/000119312526206910/ownership.xml","form_type":"4"}},{"id":1011235,"issuer":{"id":73682,"kind":"organization","name":"89bio, Inc.","symbol":"ETNB"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-10-31T00:18:47.000Z","date":"2025-10-30","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":56400,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Disposed of pursuant to the Agreement and Plan of Merger (the \"Merger Agreement\"), dated as of September 17, 2025, by and among 89bio, Inc. (the \"Issuer\"), Roche Holdings, Inc. (\"Parent\") and Bluefin Merger Subsidiary, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"). On October 30, 2025, Parent and Merger Sub completed a tender offer pursuant to the terms of the Merger Agreement for all outstanding shares of common stock of the Issuer (each, a \"Share\") for an offer price of (i) $14.50 per Share in cash, without interest (the \"Closing Amount\") less any required withholding taxes, plus (ii) one non-tradeable contingent value right (each, a \"CVR\") representing the right to receive certain contingent payments of up to an aggregate amount of $6.00 per Share, [continues to Footnote 2]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"[continues from Footnote 1] in cash, without interest less any required withholding taxes, upon the achievement of specified milestones on or prior to the applicable milestone outside dates, subject to and in accordance with the terms of the Contingent Value Rights Agreement (the \"CVR Agreement\"). Merger Sub thereafter merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent (the \"Merger\")."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"As of immediately prior to and conditioned upon the occurrence of the effective time of the Merger, pursuant to the Merger Agreement, each outstanding option to purchase Shares (each, an \"Option\") became fully vested and exercisable, and to the extent not exercised prior to the effective time of the Merger, was cancelled and converted into the right to receive (i) an amount in cash (without interest and subject to deduction for any required withholding taxes) equal to the product of (A) an amount equal to the excess of the Closing Amount over the exercise price per Share with respect to such Option and (B) the number of Shares subject to such Option plus (ii) one CVR with respect to each Share subject to such Option (the \"Option Consideration\"); provided, however, that if the exercise price per Share of any Option was equal to or greater than the Closing Amount, but less than $20.50 (any such option, an \"Out of the Money Option\"), [continues to Footnote 4]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"[Continues from Footnote 3] such Out of the Money Option was not entitled to any payment of the Closing Amount in respect thereof and each Out of the Money Option was converted into the right to receive the CVR included in the Option Consideration with respect to each Share underlying such Out of the Money Option and became entitled to receive, at each time a milestone payment becomes due and payable under the terms of the CVR Agreement, an amount in cash equal to the product of (i) the number of Shares subject to such Out of the Money Option, and (ii) the amount, if any, by which (A) the Closing Amount plus the applicable milestone payment plus any other milestone payment that previously became due and payable under the terms of the CVR Agreement exceeds (B) the exercise price per Share with respect to such Out of the Money Option plus the amounts, [continues to Footnote 5]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"[Continues from Footnote 4] if any, paid to such Option holder with respect to such CVR in respect of any milestone payments that previously became due and payable under the terms of the CVR Agreement; provided further, that any Option with an exercise price that was equal to or greater than $20.50, was cancelled immediately prior to the effective time of the Merger without the receipt of any payment of the Closing Amount or CVR in respect thereof."}],"balance_after":0,"derivative":{"exercise_price":9.6,"expiration_date":"2035-02-01","underlying":"Common Stock","underlying_shares":56400},"source":{"system":"sec-edgar","filing":"0001193125-25-259046","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1278219/000119312525259046/ownership.xml","form_type":"4"}},{"id":1011234,"issuer":{"id":73682,"kind":"organization","name":"89bio, Inc.","symbol":"ETNB"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-10-31T00:18:47.000Z","date":"2025-10-30","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":45150,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Disposed of pursuant to the Agreement and Plan of Merger (the \"Merger Agreement\"), dated as of September 17, 2025, by and among 89bio, Inc. (the \"Issuer\"), Roche Holdings, Inc. (\"Parent\") and Bluefin Merger Subsidiary, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"). On October 30, 2025, Parent and Merger Sub completed a tender offer pursuant to the terms of the Merger Agreement for all outstanding shares of common stock of the Issuer (each, a \"Share\") for an offer price of (i) $14.50 per Share in cash, without interest (the \"Closing Amount\") less any required withholding taxes, plus (ii) one non-tradeable contingent value right (each, a \"CVR\") representing the right to receive certain contingent payments of up to an aggregate amount of $6.00 per Share, [continues to Footnote 2]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"[continues from Footnote 1] in cash, without interest less any required withholding taxes, upon the achievement of specified milestones on or prior to the applicable milestone outside dates, subject to and in accordance with the terms of the Contingent Value Rights Agreement (the \"CVR Agreement\"). Merger Sub thereafter merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent (the \"Merger\")."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"As of immediately prior to and conditioned upon the occurrence of the effective time of the Merger, pursuant to the Merger Agreement, each outstanding option to purchase Shares (each, an \"Option\") became fully vested and exercisable, and to the extent not exercised prior to the effective time of the Merger, was cancelled and converted into the right to receive (i) an amount in cash (without interest and subject to deduction for any required withholding taxes) equal to the product of (A) an amount equal to the excess of the Closing Amount over the exercise price per Share with respect to such Option and (B) the number of Shares subject to such Option plus (ii) one CVR with respect to each Share subject to such Option (the \"Option Consideration\"); provided, however, that if the exercise price per Share of any Option was equal to or greater than the Closing Amount, but less than $20.50 (any such option, an \"Out of the Money Option\"), [continues to Footnote 4]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"[Continues from Footnote 3] such Out of the Money Option was not entitled to any payment of the Closing Amount in respect thereof and each Out of the Money Option was converted into the right to receive the CVR included in the Option Consideration with respect to each Share underlying such Out of the Money Option and became entitled to receive, at each time a milestone payment becomes due and payable under the terms of the CVR Agreement, an amount in cash equal to the product of (i) the number of Shares subject to such Out of the Money Option, and (ii) the amount, if any, by which (A) the Closing Amount plus the applicable milestone payment plus any other milestone payment that previously became due and payable under the terms of the CVR Agreement exceeds (B) the exercise price per Share with respect to such Out of the Money Option plus the amounts, [continues to Footnote 5]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"[Continues from Footnote 4] if any, paid to such Option holder with respect to such CVR in respect of any milestone payments that previously became due and payable under the terms of the CVR Agreement; provided further, that any Option with an exercise price that was equal to or greater than $20.50, was cancelled immediately prior to the effective time of the Merger without the receipt of any payment of the Closing Amount or CVR in respect thereof."}],"balance_after":0,"derivative":{"exercise_price":9.98,"expiration_date":"2034-02-01","underlying":"Common Stock","underlying_shares":45150},"source":{"system":"sec-edgar","filing":"0001193125-25-259046","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1278219/000119312525259046/ownership.xml","form_type":"4"}},{"id":1011233,"issuer":{"id":73682,"kind":"organization","name":"89bio, Inc.","symbol":"ETNB"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-10-31T00:18:47.000Z","date":"2025-10-30","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":27400,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Disposed of pursuant to the Agreement and Plan of Merger (the \"Merger Agreement\"), dated as of September 17, 2025, by and among 89bio, Inc. (the \"Issuer\"), Roche Holdings, Inc. (\"Parent\") and Bluefin Merger Subsidiary, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"). On October 30, 2025, Parent and Merger Sub completed a tender offer pursuant to the terms of the Merger Agreement for all outstanding shares of common stock of the Issuer (each, a \"Share\") for an offer price of (i) $14.50 per Share in cash, without interest (the \"Closing Amount\") less any required withholding taxes, plus (ii) one non-tradeable contingent value right (each, a \"CVR\") representing the right to receive certain contingent payments of up to an aggregate amount of $6.00 per Share, [continues to Footnote 2]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"[continues from Footnote 1] in cash, without interest less any required withholding taxes, upon the achievement of specified milestones on or prior to the applicable milestone outside dates, subject to and in accordance with the terms of the Contingent Value Rights Agreement (the \"CVR Agreement\"). Merger Sub thereafter merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent (the \"Merger\")."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"As of immediately prior to and conditioned upon the occurrence of the effective time of the Merger, pursuant to the Merger Agreement, each outstanding option to purchase Shares (each, an \"Option\") became fully vested and exercisable, and to the extent not exercised prior to the effective time of the Merger, was cancelled and converted into the right to receive (i) an amount in cash (without interest and subject to deduction for any required withholding taxes) equal to the product of (A) an amount equal to the excess of the Closing Amount over the exercise price per Share with respect to such Option and (B) the number of Shares subject to such Option plus (ii) one CVR with respect to each Share subject to such Option (the \"Option Consideration\"); provided, however, that if the exercise price per Share of any Option was equal to or greater than the Closing Amount, but less than $20.50 (any such option, an \"Out of the Money Option\"), [continues to Footnote 4]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"[Continues from Footnote 3] such Out of the Money Option was not entitled to any payment of the Closing Amount in respect thereof and each Out of the Money Option was converted into the right to receive the CVR included in the Option Consideration with respect to each Share underlying such Out of the Money Option and became entitled to receive, at each time a milestone payment becomes due and payable under the terms of the CVR Agreement, an amount in cash equal to the product of (i) the number of Shares subject to such Out of the Money Option, and (ii) the amount, if any, by which (A) the Closing Amount plus the applicable milestone payment plus any other milestone payment that previously became due and payable under the terms of the CVR Agreement exceeds (B) the exercise price per Share with respect to such Out of the Money Option plus the amounts, [continues to Footnote 5]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"[Continues from Footnote 4] if any, paid to such Option holder with respect to such CVR in respect of any milestone payments that previously became due and payable under the terms of the CVR Agreement; provided further, that any Option with an exercise price that was equal to or greater than $20.50, was cancelled immediately prior to the effective time of the Merger without the receipt of any payment of the Closing Amount or CVR in respect thereof."}],"balance_after":0,"derivative":{"exercise_price":14.7,"expiration_date":"2033-02-09","underlying":"Common Stock","underlying_shares":27400},"source":{"system":"sec-edgar","filing":"0001193125-25-259046","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1278219/000119312525259046/ownership.xml","form_type":"4"}},{"id":1011232,"issuer":{"id":73682,"kind":"organization","name":"89bio, Inc.","symbol":"ETNB"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-10-31T00:18:47.000Z","date":"2025-10-30","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":25000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Disposed of pursuant to the Agreement and Plan of Merger (the \"Merger Agreement\"), dated as of September 17, 2025, by and among 89bio, Inc. (the \"Issuer\"), Roche Holdings, Inc. (\"Parent\") and Bluefin Merger Subsidiary, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"). On October 30, 2025, Parent and Merger Sub completed a tender offer pursuant to the terms of the Merger Agreement for all outstanding shares of common stock of the Issuer (each, a \"Share\") for an offer price of (i) $14.50 per Share in cash, without interest (the \"Closing Amount\") less any required withholding taxes, plus (ii) one non-tradeable contingent value right (each, a \"CVR\") representing the right to receive certain contingent payments of up to an aggregate amount of $6.00 per Share, [continues to Footnote 2]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"[continues from Footnote 1] in cash, without interest less any required withholding taxes, upon the achievement of specified milestones on or prior to the applicable milestone outside dates, subject to and in accordance with the terms of the Contingent Value Rights Agreement (the \"CVR Agreement\"). Merger Sub thereafter merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent (the \"Merger\")."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"As of immediately prior to and conditioned upon the occurrence of the effective time of the Merger, pursuant to the Merger Agreement, each outstanding option to purchase Shares (each, an \"Option\") became fully vested and exercisable, and to the extent not exercised prior to the effective time of the Merger, was cancelled and converted into the right to receive (i) an amount in cash (without interest and subject to deduction for any required withholding taxes) equal to the product of (A) an amount equal to the excess of the Closing Amount over the exercise price per Share with respect to such Option and (B) the number of Shares subject to such Option plus (ii) one CVR with respect to each Share subject to such Option (the \"Option Consideration\"); provided, however, that if the exercise price per Share of any Option was equal to or greater than the Closing Amount, but less than $20.50 (any such option, an \"Out of the Money Option\"), [continues to Footnote 4]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"[Continues from Footnote 3] such Out of the Money Option was not entitled to any payment of the Closing Amount in respect thereof and each Out of the Money Option was converted into the right to receive the CVR included in the Option Consideration with respect to each Share underlying such Out of the Money Option and became entitled to receive, at each time a milestone payment becomes due and payable under the terms of the CVR Agreement, an amount in cash equal to the product of (i) the number of Shares subject to such Out of the Money Option, and (ii) the amount, if any, by which (A) the Closing Amount plus the applicable milestone payment plus any other milestone payment that previously became due and payable under the terms of the CVR Agreement exceeds (B) the exercise price per Share with respect to such Out of the Money Option plus the amounts, [continues to Footnote 5]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"[Continues from Footnote 4] if any, paid to such Option holder with respect to such CVR in respect of any milestone payments that previously became due and payable under the terms of the CVR Agreement; provided further, that any Option with an exercise price that was equal to or greater than $20.50, was cancelled immediately prior to the effective time of the Merger without the receipt of any payment of the Closing Amount or CVR in respect thereof."}],"balance_after":0,"derivative":{"exercise_price":2.64,"expiration_date":"2032-05-16","underlying":"Common Stock","underlying_shares":25000},"source":{"system":"sec-edgar","filing":"0001193125-25-259046","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1278219/000119312525259046/ownership.xml","form_type":"4"}},{"id":1011231,"issuer":{"id":73682,"kind":"organization","name":"89bio, Inc.","symbol":"ETNB"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-10-31T00:18:47.000Z","date":"2025-10-30","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":12500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Disposed of pursuant to the Agreement and Plan of Merger (the \"Merger Agreement\"), dated as of September 17, 2025, by and among 89bio, Inc. (the \"Issuer\"), Roche Holdings, Inc. (\"Parent\") and Bluefin Merger Subsidiary, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"). On October 30, 2025, Parent and Merger Sub completed a tender offer pursuant to the terms of the Merger Agreement for all outstanding shares of common stock of the Issuer (each, a \"Share\") for an offer price of (i) $14.50 per Share in cash, without interest (the \"Closing Amount\") less any required withholding taxes, plus (ii) one non-tradeable contingent value right (each, a \"CVR\") representing the right to receive certain contingent payments of up to an aggregate amount of $6.00 per Share, [continues to Footnote 2]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"[continues from Footnote 1] in cash, without interest less any required withholding taxes, upon the achievement of specified milestones on or prior to the applicable milestone outside dates, subject to and in accordance with the terms of the Contingent Value Rights Agreement (the \"CVR Agreement\"). Merger Sub thereafter merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent (the \"Merger\")."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"As of immediately prior to and conditioned upon the occurrence of the effective time of the Merger, pursuant to the Merger Agreement, each outstanding option to purchase Shares (each, an \"Option\") became fully vested and exercisable, and to the extent not exercised prior to the effective time of the Merger, was cancelled and converted into the right to receive (i) an amount in cash (without interest and subject to deduction for any required withholding taxes) equal to the product of (A) an amount equal to the excess of the Closing Amount over the exercise price per Share with respect to such Option and (B) the number of Shares subject to such Option plus (ii) one CVR with respect to each Share subject to such Option (the \"Option Consideration\"); provided, however, that if the exercise price per Share of any Option was equal to or greater than the Closing Amount, but less than $20.50 (any such option, an \"Out of the Money Option\"), [continues to Footnote 4]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"[Continues from Footnote 3] such Out of the Money Option was not entitled to any payment of the Closing Amount in respect thereof and each Out of the Money Option was converted into the right to receive the CVR included in the Option Consideration with respect to each Share underlying such Out of the Money Option and became entitled to receive, at each time a milestone payment becomes due and payable under the terms of the CVR Agreement, an amount in cash equal to the product of (i) the number of Shares subject to such Out of the Money Option, and (ii) the amount, if any, by which (A) the Closing Amount plus the applicable milestone payment plus any other milestone payment that previously became due and payable under the terms of the CVR Agreement exceeds (B) the exercise price per Share with respect to such Out of the Money Option plus the amounts, [continues to Footnote 5]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"[Continues from Footnote 4] if any, paid to such Option holder with respect to such CVR in respect of any milestone payments that previously became due and payable under the terms of the CVR Agreement; provided further, that any Option with an exercise price that was equal to or greater than $20.50, was cancelled immediately prior to the effective time of the Merger without the receipt of any payment of the Closing Amount or CVR in respect thereof."}],"balance_after":0,"derivative":{"exercise_price":24.16,"expiration_date":"2031-04-15","underlying":"Common Stock","underlying_shares":12500},"source":{"system":"sec-edgar","filing":"0001193125-25-259046","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1278219/000119312525259046/ownership.xml","form_type":"4"}},{"id":1011230,"issuer":{"id":73682,"kind":"organization","name":"89bio, Inc.","symbol":"ETNB"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-10-31T00:18:47.000Z","date":"2025-10-30","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":20000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Disposed of pursuant to the Agreement and Plan of Merger (the \"Merger Agreement\"), dated as of September 17, 2025, by and among 89bio, Inc. (the \"Issuer\"), Roche Holdings, Inc. (\"Parent\") and Bluefin Merger Subsidiary, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"). On October 30, 2025, Parent and Merger Sub completed a tender offer pursuant to the terms of the Merger Agreement for all outstanding shares of common stock of the Issuer (each, a \"Share\") for an offer price of (i) $14.50 per Share in cash, without interest (the \"Closing Amount\") less any required withholding taxes, plus (ii) one non-tradeable contingent value right (each, a \"CVR\") representing the right to receive certain contingent payments of up to an aggregate amount of $6.00 per Share, [continues to Footnote 2]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"[continues from Footnote 1] in cash, without interest less any required withholding taxes, upon the achievement of specified milestones on or prior to the applicable milestone outside dates, subject to and in accordance with the terms of the Contingent Value Rights Agreement (the \"CVR Agreement\"). Merger Sub thereafter merged with and into the Issuer, with the Issuer continuing as the surviving corporation and a wholly owned subsidiary of Parent (the \"Merger\")."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"As of immediately prior to and conditioned upon the occurrence of the effective time of the Merger, pursuant to the Merger Agreement, each outstanding option to purchase Shares (each, an \"Option\") became fully vested and exercisable, and to the extent not exercised prior to the effective time of the Merger, was cancelled and converted into the right to receive (i) an amount in cash (without interest and subject to deduction for any required withholding taxes) equal to the product of (A) an amount equal to the excess of the Closing Amount over the exercise price per Share with respect to such Option and (B) the number of Shares subject to such Option plus (ii) one CVR with respect to each Share subject to such Option (the \"Option Consideration\"); provided, however, that if the exercise price per Share of any Option was equal to or greater than the Closing Amount, but less than $20.50 (any such option, an \"Out of the Money Option\"), [continues to Footnote 4]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"[Continues from Footnote 3] such Out of the Money Option was not entitled to any payment of the Closing Amount in respect thereof and each Out of the Money Option was converted into the right to receive the CVR included in the Option Consideration with respect to each Share underlying such Out of the Money Option and became entitled to receive, at each time a milestone payment becomes due and payable under the terms of the CVR Agreement, an amount in cash equal to the product of (i) the number of Shares subject to such Out of the Money Option, and (ii) the amount, if any, by which (A) the Closing Amount plus the applicable milestone payment plus any other milestone payment that previously became due and payable under the terms of the CVR Agreement exceeds (B) the exercise price per Share with respect to such Out of the Money Option plus the amounts, [continues to Footnote 5]"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"[Continues from Footnote 4] if any, paid to such Option holder with respect to such CVR in respect of any milestone payments that previously became due and payable under the terms of the CVR Agreement; provided further, that any Option with an exercise price that was equal to or greater than $20.50, was cancelled immediately prior to the effective time of the Merger without the receipt of any payment of the Closing Amount or CVR in respect thereof."}],"balance_after":0,"derivative":{"exercise_price":24.05,"expiration_date":"2030-06-12","underlying":"Common Stock","underlying_shares":20000},"source":{"system":"sec-edgar","filing":"0001193125-25-259046","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1278219/000119312525259046/ownership.xml","form_type":"4"}},{"id":1109567,"issuer":{"id":6638,"kind":"organization","name":"enGene Therapeutics Inc.","symbol":"ENGN"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true}}],"security":"Stock Option (Right to Buy)","published_at":"2025-06-16T22:40:38.000Z","date":"2025-06-16","kind":"grant","planned":false,"acquired":true,"shares":22500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option fully vests on the earlier of (i) the first anniversary of the date vesting commenced, which was June 10, 2025; 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These restricted stock units vested 100% on May 21, 2025."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Each restricted stock unit represents a contingent right to receive one share of common stock. These restricted stock units vested 100% on May 21, 2025."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Each restricted stock unit represents a contingent right to receive one share of common stock. These restricted stock units vested 100% on May 21, 2025."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":2167},"source":{"system":"sec-edgar","filing":"0001055726-25-000040","document":"wk-form4_1747861110.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1055726/000105572625000040/wk-form4_1747861110.xml","form_type":"4"}},{"id":1139371,"issuer":{"id":6589,"kind":"organization","name":"INOVIO PHARMACEUTICALS, INC."},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2025-05-21T20:58:38.000Z","date":"2025-05-21","kind":"exercise","planned":false,"acquired":true,"shares":2167,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each restricted stock unit represents a contingent right to receive one share of common stock. 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dated February 22, 2019, by and between Spark Therapeutics, Inc. (\"Spark\"), Roche Holdings, Inc. (\"Roche\") and 022019 Merger Subsidiary, Inc. (\"Merger Sub\") (the \"Merger Agreement\" and the transactions contemplated thereby, the \"Merger\"), whereby Roche caused Merger Sub to conduct a tender offer for all of the issued and outstanding shares of common stock, par value $0.001 per share, of Spark, at a price of $114.50 per share. 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In exchange, for every two cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The option vests as to 50% on the first anniversary of grant date and the remaining 50% on the second anniversary of grant date."}],"balance_after":13889,"derivative":{"exercise_price":1.77,"expiration_date":"2026-07-31","underlying":"Common Stock","underlying_shares":13889},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":18,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449725,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"disposition_to_issuer","acquired":false,"shares":27777,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F7","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every two cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The option provided that one hundred percent (100%) of the shares would vest on the earlier of (i) the first anniversary of the date of grant and (ii) the date of the first Annual Meeting following the date of grant, in each case subject to the Reporting Person's continuous service as of such date."}],"balance_after":0,"derivative":{"exercise_price":5.33,"expiration_date":"2028-05-22","underlying":"Common Stock","underlying_shares":27777},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":17,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449724,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"grant","acquired":true,"shares":4437,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every three cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The option vests as to 50% on the first anniversary of grant date and the remaining 50% on the second anniversary of grant date."}],"balance_after":4437,"derivative":{"exercise_price":1.77,"expiration_date":"2026-07-31","underlying":"Common Stock","underlying_shares":4437},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":16,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449723,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"disposition_to_issuer","acquired":false,"shares":13309,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every three cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The option provided that one hundred percent (100%) of the shares would vest on the earlier of (i) the first anniversary of the date of grant and (ii) the date of the first Annual Meeting following the date of grant, in each case subject to the Reporting Person's continuous service as of such date."}],"balance_after":0,"derivative":{"exercise_price":17.42,"expiration_date":"2027-05-11","underlying":"Common Stock","underlying_shares":13309},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":15,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449722,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"grant","acquired":true,"shares":2392,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F7","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every two cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The option vests as to 50% on the first anniversary of grant date and the remaining 50% on the second anniversary of grant date."}],"balance_after":2392,"derivative":{"exercise_price":1.77,"expiration_date":"2026-07-31","underlying":"Common Stock","underlying_shares":2392},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":14,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449721,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"disposition_to_issuer","acquired":false,"shares":4783,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F7","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every two cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The option provided that one hundred percent (100%) of the shares would vest on the earlier of (i) the first anniversary of the date of grant and (ii) the date of the first Annual Meeting following the date of grant, in each case subject to the Reporting Person's continuous service as of such date."}],"balance_after":0,"derivative":{"exercise_price":10.78,"expiration_date":"2026-08-08","underlying":"Common Stock","underlying_shares":4783},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":13,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449720,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"grant","acquired":true,"shares":8887,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F7","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every two cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The option vests as to 50% on the first anniversary of grant date and the remaining 50% on the second anniversary of grant date."}],"balance_after":8887,"derivative":{"exercise_price":1.77,"expiration_date":"2026-07-31","underlying":"Common Stock","underlying_shares":8887},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":12,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449719,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"disposition_to_issuer","acquired":false,"shares":17773,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F7","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every two cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The option provided that one hundred percent (100%) of the shares would vest on the earlier of (i) the first anniversary of the date of grant and (ii) the date of the first Annual Meeting following the date of grant, in each case subject to the Reporting Person's continuous service as of such date."}],"balance_after":0,"derivative":{"exercise_price":10.78,"expiration_date":"2026-08-08","underlying":"Common Stock","underlying_shares":17773},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":11,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449718,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"grant","acquired":true,"shares":1588,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F6","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every four cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The option vests as to 50% on the first anniversary of grant date and the remaining 50% on the second anniversary of grant date."}],"balance_after":1588,"derivative":{"exercise_price":1.77,"expiration_date":"2026-07-31","underlying":"Common Stock","underlying_shares":1588},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":10,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449717,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"disposition_to_issuer","acquired":false,"shares":6349,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F6","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every four cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The option provided that one hundred percent (100%) of the shares would vest on the earlier of (i) the first anniversary of the date of grant and (ii) the date of the first Annual Meeting following the date of grant, in each case subject to the Reporting Person's continuous service as of such date."}],"balance_after":0,"derivative":{"exercise_price":44.6,"expiration_date":"2025-04-29","underlying":"Common Stock","underlying_shares":6349},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":9,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449716,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"grant","acquired":true,"shares":5220,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every three cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The option vests as to 50% on the first anniversary of grant date and the remaining 50% on the second anniversary of grant date."}],"balance_after":5220,"derivative":{"exercise_price":1.77,"expiration_date":"2026-07-31","underlying":"Common Stock","underlying_shares":5220},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449715,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"disposition_to_issuer","acquired":false,"shares":15659,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every three cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The option provided that one hundred percent (100%) of the shares would vest on the earlier of (i) the first anniversary of the date of grant and (ii) the date of the first Annual Meeting following the date of grant, in each case subject to the Reporting Person's continuous service as of such date."}],"balance_after":0,"derivative":{"exercise_price":21.23,"expiration_date":"2024-04-30","underlying":"Common Stock","underlying_shares":15659},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449714,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"grant","acquired":true,"shares":4000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every three cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The option vests as to 50% on the first anniversary of grant date and the remaining 50% on the second anniversary of grant date."}],"balance_after":4000,"derivative":{"exercise_price":1.77,"expiration_date":"2026-07-31","underlying":"Common Stock","underlying_shares":4000},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449713,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"grant","acquired":false,"shares":12000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every three cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The option provided that one hundred percent (100%) of the shares would vest on the earlier of (i) the first anniversary of the date of grant and (ii) the date of the first Annual Meeting following the date of grant, in each case subject to the Reporting Person's continuous service as of such date."}],"balance_after":0,"derivative":{"exercise_price":14.71,"expiration_date":"2023-05-08","underlying":"Common Stock","underlying_shares":12000},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449712,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"grant","acquired":true,"shares":3571,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  In exchange, for every three cancelled options, the reporting person received a replacement option having an exercise price of $1.77 per share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The option vests as to 50% on the first anniversary of grant date and the remaining 50% on the second anniversary of grant date."}],"balance_after":3571,"derivative":{"exercise_price":1.77,"expiration_date":"2026-07-31","underlying":"Common Stock","underlying_shares":3571},"source":{"system":"sec-edgar","filing":"0001126234-19-000104","document":"wf-form4_156478554000686.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1126234/000112623419000104/wf-form4_156478554000686.xml","form_type":"4"}},{"id":3449711,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-08-02T18:39:16.000Z","date":"2019-07-31","kind":"disposition_to_issuer","acquired":false,"shares":10713,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"On July 31, 2019, the issuer cancelled this option grant pursuant to the issuer's option exchange program.  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Vested shares are delivered to the reporting person on the vesting date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"On May 30, 2018, the reporting person was granted 1,500 restricted stock units that vest on the one-year anniversary of the grant date.  Vested shares are delivered to the reporting person on the vesting date."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":1500},"source":{"system":"sec-edgar","filing":"0001609351-19-000061","document":"wf-form4_155959318380504.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1278219/000160935119000061/wf-form4_155959318380504.xml","form_type":"4"}},{"id":3504358,"issuer":{"id":153045,"kind":"organization","name":"Spark Therapeutics, Inc.","symbol":"ONCE"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2019-06-03T20:19:59.000Z","date":"2019-05-30","kind":"exercise","acquired":true,"shares":1500,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each restricted stock unit converted into one share of Spark Therapeutics, Inc. common stock."}],"balance_after":3000,"source":{"system":"sec-edgar","filing":"0001609351-19-000061","document":"wf-form4_155959318380504.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1278219/000160935119000061/wf-form4_155959318380504.xml","form_type":"4"}},{"id":3527930,"issuer":{"id":85102,"kind":"organization","name":"LUMOS PHARMA, INC.","symbol":"(LUMO)"},"owners":[{"id":37177,"kind":"person","name":"Zoth Lota S.","position":1,"cik":"0001278219","reported_name":"Zoth Lota S.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2019-05-14T17:34:52.000Z","date":"2019-05-10","kind":"grant","acquired":true,"shares":25000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Automatic grant to the Reporting Person of a nonstatutory stock option under the Issuer's 2009 Equity Incentive Plan, as amended (the \"Plan\").  One hundred percent (100%) of the shares shall vest on the earlier of (i) the first anniversary of the date of grant and (ii) the date of the first Annual Meeting following the date of grant, in each case subject to the Reporting Person's continuous service as of such date.  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These restricted stock units will vest 100% on May 8, 2020."},{"field":"shares","element":"transactionShares","label":"F1","text":"This grant was made pursuant to the issuer's non-employee director compensation policy."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"Each restricted stock unit represents a contingent right to receive one share of common stock. These restricted stock units will vest 100% on May 8, 2020."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"Each restricted stock unit represents a contingent right to receive one share of common stock. 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