{"transactions":[{"id":733322,"issuer":{"id":275,"kind":"organization","name":"Zenas BioPharma, Inc.","symbol":"ZBIO"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2026-06-17T22:02:33.000Z","date":"2026-06-15","kind":"grant","planned":false,"acquired":true,"shares":18500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests as to 100% of the underlying shares of common stock on June 15, 2027, the first anniversary of the vesting commencement date, subject to continued service."}],"balance_after":18500,"derivative":{"exercise_price":18.71,"expiration_date":"2036-06-15","underlying":"Common Stock","underlying_shares":18500},"source":{"system":"sec-edgar","filing":"0001104659-26-075255","document":"tm2618042-7_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1643941/000110465926075255/tm2618042-7_4seq1.xml","form_type":"4"}},{"id":1112864,"issuer":{"id":275,"kind":"organization","name":"Zenas BioPharma, Inc.","symbol":"ZBIO"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-06-12T20:32:14.000Z","date":"2025-06-10","kind":"grant","planned":false,"acquired":true,"shares":18500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests as to 100% of the underlying shares of common stock on June 10, 2026, the first anniversary of the vesting commencement date, subject to continued service."}],"balance_after":18500,"derivative":{"exercise_price":11.94,"expiration_date":"2035-06-10","underlying":"Common Stock","underlying_shares":18500},"source":{"system":"sec-edgar","filing":"0001104659-25-058922","document":"tm2517684-3_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1643941/000110465925058922/tm2517684-3_4seq1.xml","form_type":"4"}},{"id":1406344,"issuer":{"id":275,"kind":"organization","name":"Zenas BioPharma, Inc.","symbol":"ZBIO"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2024-09-17T01:05:31.000Z","date":"2024-09-12","kind":"grant","planned":false,"acquired":true,"shares":18500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests as to 100% of the underlying shares of common stock on September 12, 2025, the first anniversary of the vesting commencement date, subject to continued service."}],"balance_after":18500,"derivative":{"exercise_price":17,"expiration_date":"2034-09-11","underlying":"Common Stock","underlying_shares":18500},"source":{"system":"sec-edgar","filing":"0001104659-24-100339","document":"tm2424157-2_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1643941/000110465924100339/tm2424157-2_4seq1.xml","form_type":"4"}},{"id":2626534,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2021-07-23T16:29:42.000Z","date":"2021-07-21","kind":"disposition_to_issuer","acquired":false,"shares":146511,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents shares of Alexion common stock disposed in connection with the Agreement and Plan of Merger (the \"Merger Agreement\") dated as of December 12, 2020, by and among Alexion and AstraZeneca PLC.  In accordance with the Merger Agreement, upon the First Effective Time (as defined in the Merger Agreement), each share of Alexion common stock was converted into the right to receive (i) 2.1423 American Depositary Shares (ADSs) of AstraZeneca PLC and (ii) $60.00 in cash (the \"Merger Consideration\")."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0000899866-21-000062","document":"wf-form4_162707216366619.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986621000062/wf-form4_162707216366619.xml","form_type":"4"}},{"id":2632534,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2021-07-16T16:48:02.000Z","date":"2021-07-14","kind":"grant","acquired":true,"shares":29501,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"On July 14, 2021 the Leadership and Compensation Committee certified that certain performance metrics under previously granted performance stock units were satisfied.  These performance stock units were previously granted in February 2020 under the 2017 Stock Incentive Plan."}],"balance_after":146511,"source":{"system":"sec-edgar","filing":"0000899866-21-000054","document":"wf-form4_162646847074936.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986621000054/wf-form4_162646847074936.xml","form_type":"4"}},{"id":2632533,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2021-07-16T16:48:02.000Z","date":"2021-07-14","kind":"grant","acquired":true,"shares":30643,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"On July 14, 2021 the Leadership and Compensation Committee certified that certain performance metrics under previously granted performance stock units were satisfied.  These performance stock units were previously granted in February 2019 under the 2017 Stock Incentive Plan."}],"balance_after":117010,"source":{"system":"sec-edgar","filing":"0000899866-21-000054","document":"wf-form4_162646847074936.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986621000054/wf-form4_162646847074936.xml","form_type":"4"}},{"id":2676495,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2021-06-09T16:53:56.000Z","date":"2021-06-08","kind":"tax_withholding","acquired":false,"shares":1957,"price":177,"value":346389.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This sale was made to cover withholding taxes immediately following the vesting of previously granted Restricted Stock Units."}],"balance_after":86367,"source":{"system":"sec-edgar","filing":"0000899866-21-000050","document":"wf-form4_162327201970263.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986621000050/wf-form4_162327201970263.xml","form_type":"4"}},{"id":2822829,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2021-03-02T17:50:40.000Z","date":"2021-02-28","kind":"grant","acquired":true,"shares":24473,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Award of Restricted Stock Units under the 2017 Incentive Plan.  25% vests on each anniversary of the grant date."}],"balance_after":88324,"source":{"system":"sec-edgar","filing":"0000899866-21-000023","document":"wf-form4_161472540804716.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986621000023/wf-form4_161472540804716.xml","form_type":"4"}},{"id":2938549,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2020-12-18T17:06:36.000Z","date":"2020-12-15","kind":"grant","acquired":true,"shares":40,"price":93.53,"value":3741.2,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F4","text":"In accordance with the Alexion ESPP, these shares were purchased (for the ESPP purchase period from July 1, 2020 to December 15, 2020) based on 85% of the share price on July 1, 2020."}],"balance_after":63851,"source":{"system":"sec-edgar","filing":"0000899866-20-000093","document":"wf-form4_160832918352160.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986620000093/wf-form4_160832918352160.xml","form_type":"4"}},{"id":2938548,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2020-12-18T17:06:36.000Z","date":"2020-12-16","kind":"tax_withholding","acquired":false,"shares":3261,"price":157.96,"value":515107.56,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F3","text":"This sale was made to cover withholding taxes immediately following the vesting of previously granted Restricted Stock Units."}],"balance_after":63811,"source":{"system":"sec-edgar","filing":"0000899866-20-000093","document":"wf-form4_160832918352160.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986620000093/wf-form4_160832918352160.xml","form_type":"4"}},{"id":2938547,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2020-12-18T17:06:36.000Z","date":"2020-12-16","kind":"tax_withholding","acquired":false,"shares":18134,"price":157.96,"value":2864446.64,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"This sale was made to cover withholding taxes immediately following the vesting of previously granted Performance Stock Units."}],"balance_after":67072,"source":{"system":"sec-edgar","filing":"0000899866-20-000093","document":"wf-form4_160832918352160.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986620000093/wf-form4_160832918352160.xml","form_type":"4"}},{"id":2938546,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2020-12-18T17:06:36.000Z","date":"2020-12-16","kind":"grant","acquired":true,"shares":40677,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Shares acquired on vesting of Performance Stock Units previously granted on February 28, 2018 under the 2017 Stock Incentive Plan."}],"balance_after":85206,"source":{"system":"sec-edgar","filing":"0000899866-20-000093","document":"wf-form4_160832918352160.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986620000093/wf-form4_160832918352160.xml","form_type":"4"}},{"id":3117533,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2020-06-09T16:59:59.000Z","date":"2020-06-08","kind":"tax_withholding","acquired":false,"shares":2784,"price":114.61,"value":319074.24,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This sale was made to cover withholding taxes immediately following the vesting of previously granted Restricted Stock Units."}],"balance_after":44529,"source":{"system":"sec-edgar","filing":"0000899866-20-000063","document":"wf-form4_159173638161609.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986620000063/wf-form4_159173638161609.xml","form_type":"4"}},{"id":3235213,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2020-03-03T18:26:37.000Z","date":"2019-12-15","kind":"grant","acquired":true,"shares":38,"price":93.86,"value":3566.68,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F4","text":"In accordance with the Alexion ESPP, these shares were purchased (for the ESPP purchase period from June 30, 2019 to December 15, 2019) based on 85% of the closing price of the Issuer's common stock on December 15, 2019."}],"balance_after":47313,"source":{"system":"sec-edgar","filing":"0000899866-20-000023","document":"wf-form4_158327798024153.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986620000023/wf-form4_158327798024153.xml","form_type":"4"}},{"id":3235212,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2020-03-03T18:26:37.000Z","date":"2020-03-02","kind":"tax_withholding","acquired":false,"shares":1396,"price":90.54,"value":126393.84,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"This sale was made to cover withholding taxes immediately following the vesting of previously granted Restricted Stock Units."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"This transaction was executed in multiple trades through a broker-dealer at prices ranging from $90.48 - $92.45.  The price reported in this column reflects the weighted average sales price.  Upon request, the reporting person will provide to the SEC staff full information regarding the number of shares sold at each price."}],"balance_after":47275,"source":{"system":"sec-edgar","filing":"0000899866-20-000023","document":"wf-form4_158327798024153.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986620000023/wf-form4_158327798024153.xml","form_type":"4"}},{"id":3235211,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2020-03-03T18:26:37.000Z","date":"2020-02-28","kind":"grant","acquired":true,"shares":10880,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Award of Restricted Stock Units under the 2017 Incentive Plan.  25% vests on each anniversary of the grant date."}],"balance_after":48671,"source":{"system":"sec-edgar","filing":"0000899866-20-000023","document":"wf-form4_158327798024153.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986620000023/wf-form4_158327798024153.xml","form_type":"4"}},{"id":3495051,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2019-06-11T18:39:56.000Z","date":"2019-06-07","kind":"tax_withholding","acquired":false,"shares":2786,"price":118.61,"value":330447.46,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This sale was made to cover withholding taxes immediately following the vesting of previously granted Restricted Stock Units."}],"balance_after":37791,"source":{"system":"sec-edgar","filing":"0000899866-19-000077","document":"wf-form4_156029278196014.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986619000077/wf-form4_156029278196014.xml","form_type":"4"}},{"id":3615677,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2019-03-05T20:18:07.000Z","date":"2019-02-28","kind":"grant","acquired":true,"shares":9428,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Award of Restricted Stock Units under the 2017 Incentive Plan.  25% vests on each anniversary of the grant date."}],"balance_after":40577,"source":{"system":"sec-edgar","filing":"0000899866-19-000048","document":"wf-form4_155183507279607.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986619000048/wf-form4_155183507279607.xml","form_type":"4"}},{"id":3620733,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2019-03-04T17:42:16.000Z","date":"2018-12-15","kind":"grant","acquired":true,"shares":34,"price":93.01,"value":3162.34,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F3","text":"In accordance with the Alexion ESPP, these shares were purchased (for the ESPP purchase period from June 30, 2018 to December 15, 2018) based on 85% of the closing price of the Issuer's common stock on December 15, 2018."}],"balance_after":31149,"source":{"system":"sec-edgar","filing":"0000899866-19-000041","document":"wf-form4_155173932177992.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986619000041/wf-form4_155173932177992.xml","form_type":"4"}},{"id":3620732,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2019-03-04T17:42:16.000Z","date":"2019-02-28","kind":"tax_withholding","acquired":false,"shares":675,"price":132.92,"value":89721.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This sale was made to cover withholding taxes immediately following the vesting of previously granted Restricted Stock Units."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"This transaction was executed in multiple trades through a broker-dealer at prices ranging from $132.90- $135.01. The price reported in this column reflects the weighted average sales price. Upon request, the reporting person will provide to the SEC staff full information regarding the number of shares sold at each price."}],"balance_after":31115,"source":{"system":"sec-edgar","filing":"0000899866-19-000041","document":"wf-form4_155173932177992.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986619000041/wf-form4_155173932177992.xml","form_type":"4"}},{"id":3846604,"issuer":{"id":152369,"kind":"organization","name":"NOVELION THERAPEUTICS INC.","symbol":"NVLNF"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2018-08-13T16:31:19.000Z","date":"2018-08-09","kind":"grant","acquired":true,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each option has an exercise price equal to the closing price of a common share of the Issuer on the Nasdaq Global Select Market on the grant date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option shall vest in twelve equal monthly installments, beginning one month after the grant date."}],"balance_after":10000,"derivative":{"exercise_price":3.33,"expiration_date":"2028-08-09","underlying":"Common Shares","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001104659-18-051506","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/827809/000110465918051506/a4.xml","form_type":"4"}},{"id":3897510,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2018-06-12T16:51:01.000Z","date":"2018-06-08","kind":"sale","acquired":false,"shares":2115,"price":118.53,"value":250690.95,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This sale was made to cover withholding taxes immediately following the vesting of previously granted Restricted Stock Units."}],"balance_after":31790,"source":{"system":"sec-edgar","filing":"0000899866-18-000101","document":"wf-form4_152883664251133.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986618000101/wf-form4_152883664251133.xml","form_type":"4"}},{"id":4021788,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2018-03-02T17:00:33.000Z","date":"2018-02-28","kind":"grant","acquired":true,"shares":8940,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Award of Restricted Stock Units under the 2017 Incentive Plan.  25% vests on each anniversary of the grant date."}],"balance_after":33905,"source":{"system":"sec-edgar","filing":"0000899866-18-000059","document":"wf-form4_152002801458348.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986618000059/wf-form4_152002801458348.xml","form_type":"4"}},{"id":4266239,"issuer":{"id":152369,"kind":"organization","name":"NOVELION THERAPEUTICS INC.","symbol":"NVLNF"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2017-07-05T16:01:26.000Z","date":"2017-07-03","kind":"grant","acquired":true,"shares":9600,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each option has an exercise price equal to the closing price of a common share of the Issuer on the Nasdaq Global Select Market on the grant date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The common shares underlying this stock option award will vest in equal monthly installments over 36 months, beginning one month after the grant date."}],"balance_after":9600,"derivative":{"exercise_price":9.37,"expiration_date":"2027-07-03","underlying":"Common Shares","underlying_shares":9600},"source":{"system":"sec-edgar","filing":"0001104659-17-043555","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/827809/000110465917043555/a4.xml","form_type":"4"}},{"id":4287607,"issuer":{"id":137086,"kind":"organization","name":"ALEXION PHARMACEUTICALS, INC.","symbol":"ALXN"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"EVP, Research & Development"}}],"security":"Common Stock, par value $.0001 per share","published_at":"2017-06-09T18:34:31.000Z","date":"2017-06-07","kind":"grant","acquired":true,"shares":24965,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Award of Restricted Stock Units under the 2017 Incentive Plan.  25% vest on each anniversary of the grant date."}],"balance_after":24965,"source":{"system":"sec-edgar","filing":"0000899866-17-000133","document":"wf-form4_149704765549250.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/899866/000089986617000133/wf-form4_149704765549250.xml","form_type":"4"}},{"id":4512127,"issuer":{"id":152369,"kind":"organization","name":"NOVELION THERAPEUTICS INC.","symbol":"NVLNF"},"owners":[{"id":37121,"kind":"person","name":"ORLOFF JOHN J","position":1,"cik":"0001643941","reported_name":"ORLOFF JOHN J","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Stock Option (right to buy)","published_at":"2016-12-27T16:04:32.000Z","date":"2016-12-22","kind":"grant","acquired":true,"shares":166020,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each option has an exercise price equal to the closing price of a common share of the Issuer on the Nasdaq Global Select Market on the grant date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"Subject, with limited exceptions, to the Reporting Person's continued employment with the Issuer or one of its affiliates, the common shares underlying this stock option award will vest in three equal installments on December 22, 2017, December 22, 2018 and December 22, 2019."}],"balance_after":166020,"derivative":{"exercise_price":8.65,"expiration_date":"2016-12-22","underlying":"Common Shares","underlying_shares":166020},"source":{"system":"sec-edgar","filing":"0001104659-16-163870","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/827809/000110465916163870/a4.xml","form_type":"4"}}]}