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The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":48719,"source":{"system":"sec-edgar","filing":"0001628280-26-065870","document":"wk-form4_1792008382.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1856542/000162828026065870/wk-form4_1792008382.xml","form_type":"4"}},{"id":4634851,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-10-02T00:21:18.000Z","date":"2026-09-30","kind":"sale","planned":true,"acquired":false,"shares":1034,"price":34.2,"value":35362.8,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on May 28, 2026."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"This transaction was executed in multiple trades at prices ranging from $34.090 to $34.525, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":52007,"source":{"system":"sec-edgar","filing":"0001628280-26-064267","document":"wk-form4_1790886076.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1447362/000162828026064267/wk-form4_1790886076.xml","form_type":"4"}},{"id":4634850,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-10-02T00:21:18.000Z","date":"2026-09-29","kind":"sale","planned":true,"acquired":false,"shares":5543,"price":35.498,"value":196765.414,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on May 28, 2026."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"This transaction was executed in multiple trades at prices ranging from $35.010 to $35.935, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":53041,"source":{"system":"sec-edgar","filing":"0001628280-26-064267","document":"wk-form4_1790886076.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1447362/000162828026064267/wk-form4_1790886076.xml","form_type":"4"}},{"id":4619327,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-09-16T20:20:30.000Z","date":"2026-09-15","kind":"sale","planned":true,"acquired":false,"shares":3294,"price":35.142,"value":115757.748,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on May 28, 2026."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"This transaction was executed in multiple trades at prices ranging from $35.000 to $35.380, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":58584,"source":{"system":"sec-edgar","filing":"0001628280-26-062255","document":"wk-form4_1789590027.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1856542/000162828026062255/wk-form4_1789590027.xml","form_type":"4"}},{"id":4619326,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-09-16T20:20:30.000Z","date":"2026-09-14","kind":"sale","planned":true,"acquired":false,"shares":3306,"price":32.324,"value":106863.144,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on May 28, 2026."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"This transaction was executed in multiple trades at prices ranging from $32.180 to $32.445, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":61878,"source":{"system":"sec-edgar","filing":"0001628280-26-062255","document":"wk-form4_1789590027.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1856542/000162828026062255/wk-form4_1789590027.xml","form_type":"4"}},{"id":373,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-09-02T20:07:06.000Z","date":"2026-08-31","kind":"sale","planned":true,"acquired":false,"shares":1730,"price":32.81,"value":56761.3,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"This transaction was executed in multiple trades at prices ranging from $32.39 to $33.17, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":65184,"source":{"system":"sec-edgar","filing":"0001628280-26-060089","document":"wk-form4_1788379622.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1856542/000162828026060089/wk-form4_1788379622.xml","form_type":"4"}},{"id":673737,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-08-27T20:38:32.000Z","date":"2026-08-25","kind":"sale","planned":true,"acquired":false,"shares":9050,"price":35.04,"value":317112.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"This transaction was executed in multiple trades at prices ranging from $35.00 to $35.14, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":66914,"source":{"system":"sec-edgar","filing":"0001628280-26-059272","document":"wk-form4_1787863108.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1447362/000162828026059272/wk-form4_1787863108.xml","form_type":"4"}},{"id":681267,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-08-19T20:11:49.000Z","date":"2026-08-17","kind":"sale","planned":true,"acquired":false,"shares":1730,"price":29.59,"value":51190.7,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"This transaction was executed in multiple trades at prices ranging from $29.21 to $30.01, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":75964,"source":{"system":"sec-edgar","filing":"0001628280-26-057949","document":"wk-form4_1787170306.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1447362/000162828026057949/wk-form4_1787170306.xml","form_type":"4"}},{"id":694062,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-08-06T20:14:48.000Z","date":"2025-11-24","kind":"sale","planned":true,"acquired":false,"shares":1301,"price":38.39,"value":49945.39,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on September 11, 2024."}],"balance_after":77694,"source":{"system":"sec-edgar","filing":"0001628280-26-054338","document":"wk-form4_1786047286.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1447362/000162828026054338/wk-form4_1786047286.xml","form_type":"4"}},{"id":697108,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-08-04T20:36:12.000Z","date":"2026-08-03","kind":"sale","planned":true,"acquired":false,"shares":1730,"price":28.25,"value":48872.5,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F5","text":"This transaction was executed in multiple trades at prices ranging from $28.030 to $28.630, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":78995,"source":{"system":"sec-edgar","filing":"0001628280-26-052648","document":"wk-form4_1785875769.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1447362/000162828026052648/wk-form4_1785875769.xml","form_type":"4"}},{"id":697107,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-08-04T20:36:12.000Z","date":"2026-07-31","kind":"sale","planned":true,"acquired":false,"shares":1891,"price":30.264,"value":57229.224,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"This transaction was executed in multiple trades at prices ranging from $30.150 to $30.645, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":80725,"source":{"system":"sec-edgar","filing":"0001628280-26-052648","document":"wk-form4_1785875769.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1447362/000162828026052648/wk-form4_1785875769.xml","form_type":"4"}},{"id":697106,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-08-04T20:36:12.000Z","date":"2026-07-31","kind":"sale","planned":true,"acquired":false,"shares":7270,"price":29.579,"value":215039.33,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"This transaction was executed in multiple trades at prices ranging from $29.150 to $30.130, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":82616,"source":{"system":"sec-edgar","filing":"0001628280-26-052648","document":"wk-form4_1785875769.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1447362/000162828026052648/wk-form4_1785875769.xml","form_type":"4"}},{"id":697105,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-08-04T20:36:12.000Z","date":"2026-07-31","kind":"sale","planned":true,"acquired":false,"shares":8149,"price":28.842,"value":235033.458,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"This transaction was executed in multiple trades at prices ranging from $28.150 to $29.140, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":89886,"source":{"system":"sec-edgar","filing":"0001628280-26-052648","document":"wk-form4_1785875769.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1447362/000162828026052648/wk-form4_1785875769.xml","form_type":"4"}},{"id":763616,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Stock option (right to buy)","published_at":"2026-05-26T20:06:38.000Z","date":"2026-05-21","kind":"exercise","planned":false,"acquired":false,"shares":11210,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option are fully vested."}],"balance_after":0,"derivative":{"exercise_price":3.38,"expiration_date":"2029-03-12","underlying":"Common Stock","underlying_shares":11210},"source":{"system":"sec-edgar","filing":"0001628280-26-038072","document":"wk-form4_1779825996.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1447362/000162828026038072/wk-form4_1779825996.xml","form_type":"4"}},{"id":763615,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-05-26T20:06:38.000Z","date":"2026-05-21","kind":"exercise","planned":false,"acquired":true,"shares":11210,"price":3.38,"value":37889.8,"ownership":{"direct":true},"balance_after":98035,"source":{"system":"sec-edgar","filing":"0001628280-26-038072","document":"wk-form4_1779825996.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1447362/000162828026038072/wk-form4_1779825996.xml","form_type":"4"}},{"id":841506,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Common Stock","published_at":"2026-03-16T20:07:57.000Z","date":"2026-03-12","kind":"sale","planned":true,"acquired":false,"shares":20863,"price":25.24,"value":526582.12,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This transaction was made pursuant to a Rule 10b5-1 plan adopted by the Reporting Person on December 10, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"This transaction was executed in multiple trades at prices ranging from $24.90 to $25.70, inclusive. The price reported above reflects the weighted-average sale price. The Reporting Person hereby undertakes to provide upon request to the Securities and Exchange Commission staff, the issuer or a security holder of the issuer full information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":86825,"source":{"system":"sec-edgar","filing":"0001628280-26-018156","document":"wk-form4_1773691674.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1447362/000162828026018156/wk-form4_1773691674.xml","form_type":"4"}},{"id":858240,"issuer":{"id":359,"kind":"organization","name":"CASTLE BIOSCIENCES INC","symbol":"CSTL"},"owners":[{"id":360,"kind":"person","name":"Juvenal Tobin W","position":1,"cik":"0001856542","reported_name":"Juvenal Tobin W","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Commercial Officer"}}],"security":"Restricted Stock 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