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Merger Agreement, at the Effective Time, each option to purchase Shares granted under an Issuer equity plan (each, an \"Issuer Stock Option\") that was outstanding and unexercised was cancelled and converted into the right to receive a cash payment equal to (A) the excess, if any, of (x) the Offer Price over (y) the exercise price payable per Share with respect to such Issuer Stock Option, multiplied by (B) the total number of Shares subject to such Issuer Stock Option immediately prior to the Effective Time (without regard to vesting)."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under an Issuer equity plan (each, an \"Issuer Stock Option\") that was outstanding and unexercised was cancelled and converted into the right to receive a cash payment equal to (A) the excess, if any, of (x) the Offer Price over (y) the exercise price payable per Share with respect to such Issuer Stock Option, multiplied by (B) the total number of Shares subject to such Issuer Stock Option immediately prior to the Effective Time (without regard to vesting)."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F5","text":"Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under an Issuer equity plan (each, an \"Issuer Stock Option\") that was outstanding and unexercised was cancelled and converted into the right to receive a cash payment equal to (A) the excess, if any, of (x) the Offer Price over (y) the exercise price payable per Share with respect to such Issuer Stock Option, multiplied by (B) the total number of Shares subject to such Issuer Stock Option immediately prior to the Effective Time (without regard to vesting)."}],"balance_after":0,"derivative":{"exercise_price":13.87,"underlying":"Common Stock","underlying_shares":15000},"source":{"system":"sec-edgar","filing":"0001399529-21-000201","document":"wf-form4_164081283175966.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1190418/000139952921000201/wf-form4_164081283175966.xml","form_type":"4"}},{"id":2456905,"issuer":{"id":131951,"kind":"organization","name":"Dicerna Pharmaceuticals Inc","symbol":"DRNA"},"owners":[{"id":35631,"kind":"person","name":"HOFFMAN STEPHEN J","position":1,"cik":"0001190418","reported_name":"HOFFMAN STEPHEN J","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Director Stock Option (Right to Buy)","published_at":"2021-12-29T21:20:44.000Z","date":"2021-12-28","kind":"disposition_to_issuer","acquired":false,"shares":25000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F5","text":"Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under an Issuer equity plan (each, an \"Issuer Stock Option\") that was outstanding and unexercised was cancelled and converted into the right to receive a cash payment equal to (A) the excess, if any, of (x) the Offer Price over (y) the exercise price payable per Share with respect to such Issuer Stock Option, multiplied by (B) the total number of Shares subject to such Issuer Stock Option immediately prior to the Effective Time (without regard to vesting)."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under an Issuer equity plan (each, an \"Issuer Stock Option\") that was outstanding and unexercised was cancelled and converted into the right to receive a cash payment equal to (A) the excess, if any, of (x) the Offer Price over (y) the exercise price payable per Share with respect to such Issuer Stock Option, multiplied by (B) the total number of Shares subject to such Issuer Stock Option immediately prior to the Effective Time (without regard to vesting)."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F5","text":"Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under an Issuer equity plan (each, an \"Issuer Stock Option\") that was outstanding and unexercised was cancelled and converted into the right to receive a cash payment equal to (A) the excess, if any, of (x) the Offer Price over (y) the exercise price payable per Share with respect to such Issuer Stock Option, multiplied by (B) the total number of Shares subject to such Issuer Stock Option immediately prior to the Effective Time (without regard to vesting)."}],"balance_after":0,"derivative":{"exercise_price":13.08,"underlying":"Common 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Merger Agreement, at the Effective Time, each option to purchase Shares granted under an Issuer equity plan (each, an \"Issuer Stock Option\") that was outstanding and unexercised was cancelled and converted into the right to receive a cash payment equal to (A) the excess, if any, of (x) the Offer Price over (y) the exercise price payable per Share with respect to such Issuer Stock Option, multiplied by (B) the total number of Shares subject to such Issuer Stock Option immediately prior to the Effective Time (without regard to vesting)."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under an Issuer equity plan (each, an \"Issuer Stock Option\") that was outstanding and unexercised was cancelled and converted into the right to receive a cash payment equal to (A) the excess, if any, of (x) the Offer Price over (y) the exercise price payable per Share with respect to such Issuer Stock Option, multiplied by (B) the total number of Shares subject to such Issuer Stock Option immediately prior to the Effective Time (without regard to vesting)."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F5","text":"Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under an Issuer equity plan (each, an \"Issuer Stock Option\") that was outstanding and unexercised was cancelled and converted into the right to receive a cash payment equal to (A) the excess, if any, of (x) the Offer Price over (y) the exercise price payable per Share with respect to such Issuer Stock Option, multiplied by (B) the total number of Shares subject to such Issuer Stock Option immediately prior to the Effective Time (without regard to vesting)."}],"balance_after":0,"derivative":{"exercise_price":3.42,"underlying":"Common Stock","underlying_shares":25000},"source":{"system":"sec-edgar","filing":"0001399529-21-000201","document":"wf-form4_164081283175966.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1190418/000139952921000201/wf-form4_164081283175966.xml","form_type":"4"}},{"id":2456903,"issuer":{"id":131951,"kind":"organization","name":"Dicerna Pharmaceuticals Inc","symbol":"DRNA"},"owners":[{"id":35631,"kind":"person","name":"HOFFMAN STEPHEN J","position":1,"cik":"0001190418","reported_name":"HOFFMAN STEPHEN J","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Director Stock Option (Right to Buy)","published_at":"2021-12-29T21:20:44.000Z","date":"2021-12-28","kind":"disposition_to_issuer","acquired":false,"shares":15000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F5","text":"Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under an Issuer equity plan (each, an \"Issuer Stock Option\") that was outstanding and unexercised was cancelled and converted into the right to receive a cash payment equal to (A) the excess, if any, of (x) the Offer Price over (y) the exercise price payable per Share with respect to such Issuer Stock Option, multiplied by (B) the total number of Shares subject to such Issuer Stock Option immediately prior to the Effective Time (without regard to vesting)."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under an Issuer equity plan (each, an \"Issuer Stock Option\") that was outstanding and unexercised was cancelled and converted into the right to receive a cash payment equal to (A) the excess, if any, of (x) the Offer Price over (y) the exercise price payable per Share with respect to such Issuer Stock Option, multiplied by (B) the total number of Shares subject to such Issuer Stock Option immediately prior to the Effective Time (without regard to vesting)."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F5","text":"Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under an Issuer equity plan (each, an \"Issuer Stock Option\") that was outstanding and unexercised was cancelled and converted into the right to receive a cash payment equal to (A) the excess, if any, of (x) the Offer Price over (y) the exercise price payable per Share with respect to such Issuer Stock Option, multiplied by (B) the total number of Shares subject to such Issuer Stock Option immediately prior to the Effective Time (without regard to vesting)."}],"balance_after":0,"derivative":{"exercise_price":3.26,"underlying":"Common Stock","underlying_shares":15000},"source":{"system":"sec-edgar","filing":"0001399529-21-000201","document":"wf-form4_164081283175966.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1190418/000139952921000201/wf-form4_164081283175966.xml","form_type":"4"}},{"id":2456902,"issuer":{"id":131951,"kind":"organization","name":"Dicerna Pharmaceuticals Inc","symbol":"DRNA"},"owners":[{"id":35631,"kind":"person","name":"HOFFMAN STEPHEN J","position":1,"cik":"0001190418","reported_name":"HOFFMAN STEPHEN J","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Restricted Stock Units","published_at":"2021-12-29T21:20:44.000Z","date":"2021-12-28","kind":"disposition_to_issuer","acquired":false,"shares":3333,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F3","text":"Each restricted stock unit (\"RSU\") represents the contingent right to receive one Share."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"At the Effective Time, each Issuer RSU that was then outstanding was cancelled and converted into the right to receive a cash payment equal to (A) the Offer Price multiplied by (B) the total number of Shares subject to such Issuer RSU immediately prior to the Effective Time (without regard to vesting)."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"At the Effective Time, each Issuer RSU that was then outstanding was cancelled and converted into the right to receive a cash payment equal to (A) the Offer Price multiplied by (B) the total number of Shares subject to such Issuer RSU immediately prior to the Effective Time (without regard to vesting)."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F4","text":"At the Effective Time, each Issuer RSU that was then outstanding was cancelled and converted into the right to receive a cash payment equal to (A) the Offer Price multiplied by (B) the total number of Shares subject to such Issuer RSU immediately prior to the Effective Time (without regard to vesting)."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":3333},"source":{"system":"sec-edgar","filing":"0001399529-21-000201","document":"wf-form4_164081283175966.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1190418/000139952921000201/wf-form4_164081283175966.xml","form_type":"4"}},{"id":2456901,"issuer":{"id":131951,"kind":"organization","name":"Dicerna Pharmaceuticals Inc","symbol":"DRNA"},"owners":[{"id":35631,"kind":"person","name":"HOFFMAN STEPHEN J","position":1,"cik":"0001190418","reported_name":"HOFFMAN STEPHEN J","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2021-12-29T21:20:44.000Z","date":"2021-12-28","kind":"other","acquired":false,"shares":16157,"price":38.25,"value":618005.25,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the \"Merger Agreement\"), dated as of November 17, 2021, by and among the Issuer, Novo Nordisk A/S, a Danish aktieselskab (\"Novo\"), and NNUS New Research, Inc., a Delaware corporation and a wholly owned indirect subsidiary of Novo (\"Purchaser\"), to which Purchaser completed a tender offer for shares of common stock of Issuer, $0.0001 par value per share (each, a \"Share\") and thereafter merged with and into the Issuer (the \"Merger\") effective as of December 28, 2021 (the \"Effective Time\"). At the Effective Time, each issued and outstanding Share was converted into the right to receive $38.25 per Share, in cash, without interest (the \"Offer Price\") and subject to any withholding of taxes, upon the terms and subject to the conditions of the Merger Agreement. From and after the Effective Time, all Shares were no longer outstanding and were automatically cancelled."},{"field":"shares","element":"transactionShares","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the \"Merger Agreement\"), dated as of November 17, 2021, by and among the Issuer, Novo Nordisk A/S, a Danish aktieselskab (\"Novo\"), and NNUS New Research, Inc., a Delaware corporation and a wholly owned indirect subsidiary of Novo (\"Purchaser\"), to which Purchaser completed a tender offer for shares of common stock of Issuer, $0.0001 par value per share (each, a \"Share\") and thereafter merged with and into the Issuer (the \"Merger\") effective as of December 28, 2021 (the \"Effective Time\"). At the Effective Time, each issued and outstanding Share was converted into the right to receive $38.25 per Share, in cash, without interest (the \"Offer Price\") and subject to any withholding of taxes, upon the terms and subject to the conditions of the Merger Agreement. From and after the Effective Time, all Shares were no longer outstanding and were automatically cancelled."},{"field":"shares","element":"transactionShares","label":"F2","text":"Prior to the Effective Time, the Reporting Person beneficially owned 16,157 Shares, which reflects the correction of a clerical error of 90 shares previously over-reported and shares transferred to the Reporting Person's ex-spouse pursuant to a divorce decree."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Agreement and Plan of Merger (the \"Merger Agreement\"), dated as of November 17, 2021, by and among the Issuer, Novo Nordisk A/S, a Danish aktieselskab (\"Novo\"), and NNUS New Research, Inc., a Delaware corporation and a wholly owned indirect subsidiary of Novo (\"Purchaser\"), to which Purchaser completed a tender offer for shares of common stock of Issuer, $0.0001 par value per share (each, a \"Share\") and thereafter merged with and into the Issuer (the \"Merger\") effective as of December 28, 2021 (the \"Effective Time\"). At the Effective Time, each issued and outstanding Share was converted into the right to receive $38.25 per Share, in cash, without interest (the \"Offer Price\") and subject to any withholding of taxes, upon the terms and subject to the conditions of the Merger Agreement. From and after the Effective Time, all Shares were no longer outstanding and were automatically cancelled."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001399529-21-000201","document":"wf-form4_164081283175966.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1190418/000139952921000201/wf-form4_164081283175966.xml","form_type":"4"}},{"id":2663470,"issuer":{"id":7102,"kind":"organization","name":"TALPHERA, INC."},"owners":[{"id":35631,"kind":"person","name":"HOFFMAN STEPHEN J","position":1,"cik":"0001190418","reported_name":"HOFFMAN STEPHEN J","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to 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Company."}],"balance_after":21250,"source":{"system":"sec-edgar","filing":"0001209191-21-041560","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1427925/000120919121041560/doc4.xml","form_type":"4"}},{"id":2679023,"issuer":{"id":131951,"kind":"organization","name":"Dicerna Pharmaceuticals Inc","symbol":"DRNA"},"owners":[{"id":35631,"kind":"person","name":"HOFFMAN STEPHEN J","position":1,"cik":"0001190418","reported_name":"HOFFMAN STEPHEN J","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Director Stock Option (Right to Buy)","published_at":"2021-06-08T01:36:05.000Z","date":"2021-06-03","kind":"grant","acquired":true,"shares":15000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"This option vests monthly over 12 months from the Grant Date in substantially equal monthly installments, provided that the option will vest in full on the next regularly scheduled annual meeting of the stockholders of the Issuer that occurs following the Grant Date, subject to the Reporting Person's continued service to the Issuer as a director through each such date or, if earlier, such annual meeting."}],"balance_after":15000,"derivative":{"exercise_price":30.47,"expiration_date":"2031-06-02","underlying":"Common Stock","underlying_shares":15000},"source":{"system":"sec-edgar","filing":"0001399529-21-000111","document":"wf-form4_162311613423290.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1190418/000139952921000111/wf-form4_162311613423290.xml","form_type":"4"}},{"id":2679022,"issuer":{"id":131951,"kind":"organization","name":"Dicerna Pharmaceuticals Inc","symbol":"DRNA"},"owners":[{"id":35631,"kind":"person","name":"HOFFMAN STEPHEN 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Reporting Person's continued service to the Issuer as a director through such date or, if earlier, such annual meeting."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"Represents RSUs that shall vest and become nonforfeitable with respect to one-hundred percent (100%) of the total number of RSUs on the earlier of (i) 12 months from June 3, 2021 (\"Grant Date\") and (ii) the next regularly scheduled annual meeting of stockholders of the Issuer that occurs following the Grant Date, subject to the Reporting Person's continued service to the Issuer as a director through such date or, if earlier, such annual meeting."}],"balance_after":3333,"derivative":{"underlying":"Common 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