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The securities were sold in multiple transactions at per share prices ranging from $311.340 to $312.320. The Reporting Person undertakes to provide upon request from the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote."}],"balance_after":5961,"source":{"system":"sec-edgar","filing":"0001930479-26-000003","document":"wk-form4_1782508155.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":10,"url":"https://www.sec.gov/Archives/edgar/data/1689548/000193047926000003/wk-form4_1782508155.xml","form_type":"4"}},{"id":725500,"issuer":{"id":3538,"kind":"organization","name":"Praxis Precision Medicines, Inc."},"owners":[{"id":35155,"kind":"person","name":"DeSimone Jill","position":1,"cik":"0001930479","reported_name":"DeSimone Jill","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2026-06-26T21:09:23.000Z","date":"2026-06-24","kind":"sale","planned":true,"acquired":false,"shares":1750,"price":310.889,"value":544055.75,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted on March 25, 2026."},{"field":"price","element":"transactionPricePerShare","label":"F7","text":"The price reported is a weighted average price. 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The securities were sold in multiple transactions at per share prices ranging from $307.900 to $308.870. 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Each restricted stock unit represents a contingent right to receive one share of the Issuer's common stock. The restricted stock units vest in a single annual installment on the earlier of (i) June 10, 2027 or (ii) the date of the Issuer's 2027 annual meeting of stockholders. 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