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These shares were sold in multiple transactions at prices ranging from $9.8775 to $9.9000, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":4428407,"source":{"system":"sec-edgar","filing":"0001209191-21-030343","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1401667/000120919121030343/doc4.xml","form_type":"4"}},{"id":2755629,"issuer":{"id":5478,"kind":"organization","name":"PUMA BIOTECHNOLOGY, INC.","symbol":"PBYI"},"owners":[{"id":31421,"kind":"person","name":"AUERBACH ALAN H","position":1,"cik":"0001358285","reported_name":"AUERBACH ALAN H","relationship":{"director":true,"officer":true,"ten_percent_owner":true,"other":false,"officer_title":"PRESIDENT AND CEO"}}],"security":"COMMON STOCK","published_at":"2021-04-06T21:48:43.000Z","date":"2021-04-05","kind":"sale","acquired":false,"shares":1584,"price":9.8029,"value":15527.7936,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported in this Form 4 were to satisfy tax obligations in connection with the vesting of restricted stock units."}],"balance_after":4430165,"source":{"system":"sec-edgar","filing":"0001209191-21-025720","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1401667/000120919121025720/doc4.xml","form_type":"4"}},{"id":2808541,"issuer":{"id":5478,"kind":"organization","name":"PUMA BIOTECHNOLOGY, INC.","symbol":"PBYI"},"owners":[{"id":31421,"kind":"person","name":"AUERBACH ALAN H","position":1,"cik":"0001358285","reported_name":"AUERBACH ALAN H","relationship":{"director":true,"officer":true,"ten_percent_owner":true,"other":false,"officer_title":"PRESIDENT AND CEO"}}],"security":"COMMON STOCK","published_at":"2021-03-04T21:33:47.000Z","date":"2021-03-02","kind":"sale","acquired":false,"shares":1238,"price":10.1418,"value":12555.5484,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported in this Form 4 were to satisfy tax obligations in connection with the vesting of restricted stock units."}],"balance_after":4431749,"source":{"system":"sec-edgar","filing":"0001209191-21-017823","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1401667/000120919121017823/doc4.xml","form_type":"4"}},{"id":2845902,"issuer":{"id":5478,"kind":"organization","name":"PUMA BIOTECHNOLOGY, INC.","symbol":"PBYI"},"owners":[{"id":31421,"kind":"person","name":"AUERBACH ALAN H","position":1,"cik":"0001358285","reported_name":"AUERBACH ALAN H","relationship":{"director":true,"officer":true,"ten_percent_owner":true,"other":false,"officer_title":"PRESIDENT AND CEO"}}],"security":"STOCK OPTION (RIGHT TO BUY)","published_at":"2021-02-19T23:16:37.000Z","date":"2021-02-17","kind":"grant","acquired":true,"shares":210944,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"Subject to the Optionee's continued status as an Employee, the Option shall vest and become exercisable with respect to (i) one-third (1/3rd) of the Shares subject thereto on the first anniversary of January 1, 2021 (the \"Vesting Commencement Date\"), and (ii) one-sixth (1/6th) of the Shares subject thereto on each of July 1, 2022, January 1, 2023, July 1, 2023, and January 1, 2024; provided, however, that if the Optionee experiences a Termination of Service by the Company without Cause or by the Optionee with Good Reason (each as defined in Mr. Auerbach's employment agreement), in either case, during the period beginning sixty (60) days prior to and ending eighteen (18) months after the occurrence of a Change in Control, then (subject to timely executing and not revoking the Release Agreement (as defined in the employment agreement)) (i) the Option shall vest and become exercisable in full on the later to occur of such termination or the Change in Control, and (continued in footnote 4)"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"(continued from footnote 3 above) (ii) the Option shall remain exercisable until the earlier to occur of the first anniversary of such termination or the Expiration Date. 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(See footnote 2)"},{"field":"shares","element":"transactionShares","label":"F2","text":"(continued from Footnote 1 above) Unless otherwise defined herein, the terms used herein have the same defined meanings as in the Restricted Stock Unit Agreement."}],"balance_after":4432987,"source":{"system":"sec-edgar","filing":"0001209191-21-012518","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1401667/000120919121012518/doc4.xml","form_type":"4"}},{"id":2879077,"issuer":{"id":5478,"kind":"organization","name":"PUMA BIOTECHNOLOGY, INC.","symbol":"PBYI"},"owners":[{"id":31421,"kind":"person","name":"AUERBACH ALAN H","position":1,"cik":"0001358285","reported_name":"AUERBACH ALAN H","relationship":{"director":true,"officer":true,"ten_percent_owner":true,"other":false,"officer_title":"PRESIDENT AND CEO"}}],"security":"COMMON STOCK","published_at":"2021-02-04T22:10:37.000Z","date":"2021-02-02","kind":"sale","acquired":false,"shares":1222,"price":12.2183,"value":14930.7626,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported in this Form 4 were to satisfy tax obligations in connection with the vesting of restricted stock units."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $12.2101 to $12.2350, inclusive. 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STOCK","published_at":"2017-07-24T21:07:18.000Z","date":"2017-07-20","kind":"sale","acquired":false,"shares":4000,"price":95.6,"value":382400.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on December 16, 2016 to satisfy tax obligations in connection with the vesting of restricted stock units."}],"balance_after":4166623,"source":{"system":"sec-edgar","filing":"0001209191-17-046087","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1401667/000120919117046087/doc4.xml","form_type":"4"}},{"id":4252575,"issuer":{"id":5478,"kind":"organization","name":"PUMA BIOTECHNOLOGY, INC.","symbol":"PBYI"},"owners":[{"id":31421,"kind":"person","name":"AUERBACH ALAN H","position":1,"cik":"0001358285","reported_name":"AUERBACH ALAN H","relationship":{"director":true,"officer":true,"ten_percent_owner":true,"other":false,"officer_title":"PRESIDENT AND CEO"}}],"security":"COMMON STOCK","published_at":"2017-07-24T21:07:18.000Z","date":"2017-07-20","kind":"sale","acquired":false,"shares":9175,"price":94.3439,"value":865605.2825,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on December 16, 2016 to satisfy tax obligations in connection with the vesting of restricted stock units."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price. These shares were sold in two transactions with one transaction pricing at $94.10 and the other transaction pricing at  $94.35. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price set forth in this footnote."}],"balance_after":4170623,"source":{"system":"sec-edgar","filing":"0001209191-17-046087","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1401667/000120919117046087/doc4.xml","form_type":"4"}},{"id":4431341,"issuer":{"id":124173,"kind":"organization","name":"Radius Health, Inc.","symbol":"RDUS"},"owners":[{"id":31421,"kind":"person","name":"AUERBACH ALAN H","position":1,"cik":"0001358285","reported_name":"AUERBACH ALAN H","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2017-02-22T16:22:08.000Z","date":"2017-02-17","kind":"grant","acquired":true,"shares":27500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in full on February 17, 2018, subject to continued service to the Issuer through such date."}],"balance_after":27500,"derivative":{"exercise_price":45.65,"expiration_date":"2027-02-16","underlying":"Common Stock","underlying_shares":27500},"source":{"system":"sec-edgar","filing":"0001209191-17-013228","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1428522/000120919117013228/doc4.xml","form_type":"4"}},{"id":4435858,"issuer":{"id":5478,"kind":"organization","name":"PUMA BIOTECHNOLOGY, INC.","symbol":"PBYI"},"owners":[{"id":31421,"kind":"person","name":"AUERBACH ALAN H","position":1,"cik":"0001358285","reported_name":"AUERBACH ALAN H","relationship":{"director":true,"officer":true,"ten_percent_owner":true,"other":false,"officer_title":"PRESIDENT AND CEO"}}],"security":"STOCK OPTION (RIGHT TO BUY)","published_at":"2017-02-21T21:39:21.000Z","date":"2017-02-16","kind":"grant","acquired":true,"shares":70000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The vesting commencement date (\"Vesting Commencement Date\") of the option is February 16, 2017. Subject to the Reporting Person's continued status as an employee of the Issuer, the option shall vest and become exercisable with respect to one-third (1/3rd) of the shares subject thereto on the first anniversary of the Vesting Commencement Date, and with respect to an additional 1/36th of the shares subject thereto on each monthly anniversary of the Vesting Commencement Date thereafter; (continued to Footnote 2 below)"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"(Continued from Footnote 1 above) provided, however, that if the Reporting Person experiences a Termination of Service by the Issuer without Cause or by the Reporting Person with Good Reason, each as defined in the employment agreement between the Issuer and the Reporting Person dated January 19, 2012 (the \"Employment Agreement\"), in either case, during the period beginning sixty (60) days prior to and ending eighteen (18) months after the occurrence of a Change in Control, as defined in the Employment Agreement, then (subject to timely executing and not revoking the Release Agreement (as defined in the Employment Agreement)) (i) the option shall vest and become exercisable in full on the later to occur of such termination or the Change in Control, and (ii) the option shall remain exercisable until the earlier to occur of the first anniversary of such termination or the expiration date of the option reported herein."}],"balance_after":70000,"derivative":{"exercise_price":37.35,"expiration_date":"2027-02-15","underlying":"COMMON STOCK","underlying_shares":70000},"source":{"system":"sec-edgar","filing":"0001209191-17-012738","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1401667/000120919117012738/doc4.xml","form_type":"4"}},{"id":4483072,"issuer":{"id":5478,"kind":"organization","name":"PUMA BIOTECHNOLOGY, INC.","symbol":"PBYI"},"owners":[{"id":31421,"kind":"person","name":"AUERBACH ALAN H","position":1,"cik":"0001358285","reported_name":"AUERBACH ALAN H","relationship":{"director":true,"officer":true,"ten_percent_owner":true,"other":false,"officer_title":"PRESIDENT AND CEO"}}],"security":"COMMON STOCK","published_at":"2017-01-24T22:49:25.000Z","date":"2017-01-20","kind":"sale","acquired":false,"shares":10202,"price":33.2351,"value":339064.4902,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported in this Form 4 were effected pursuant to a 10b5-1 trading plan adopted by the Reporting Person on December 16, 2016 to satisfy tax obligations in connection with the vesting of restricted stock units."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $32.90 to $33.60, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in this footnote."}],"balance_after":4179798,"source":{"system":"sec-edgar","filing":"0001209191-17-005343","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1401667/000120919117005343/doc4.xml","form_type":"4"}},{"id":4579574,"issuer":{"id":5478,"kind":"organization","name":"PUMA BIOTECHNOLOGY, INC.","symbol":"PBYI"},"owners":[{"id":31421,"kind":"person","name":"AUERBACH ALAN H","position":1,"cik":"0001358285","reported_name":"AUERBACH ALAN H","relationship":{"director":true,"officer":true,"ten_percent_owner":true,"other":false,"officer_title":"PRESIDENT AND CEO"}}],"security":"COMMON STOCK","published_at":"2016-10-15T01:09:18.000Z","date":"2016-10-14","kind":"grant","acquired":true,"shares":150000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents Restricted Stock Units which vest in six substantially equal installments on each six-month anniversary of the Vesting Commencement Date of July 19, 2016, subject to the Reporting Person's continued service with the Issuer through the applicable vesting date."}],"balance_after":4190000,"source":{"system":"sec-edgar","filing":"0001209191-16-145977","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1401667/000120919116145977/doc4.xml","form_type":"4"}}]}