{"transactions":[{"id":4637418,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":29664,"kind":"person","name":"Perry Jennifer Scott","position":1,"cik":"0002119908","reported_name":"Perry Jennifer Scott","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Operating Officer"}}],"security":"Ordinary Shares","published_at":"2026-10-07T22:24:47.000Z","date":"2026-10-05","kind":"sale","planned":true,"acquired":false,"shares":326,"price":3.78,"value":1232.28,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F4","text":"This transaction was made pursuant to a Rule 10b5-1 trading plan adopted on March 27, 2025."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"The original Form 4 inadvertently overstated the number of shares sold, weighted average price and the number of shares beneficially owned following the reported transactions. This amendment correctly states the number of shares sold, weighted average price and the number of shares beneficially owned following the reported transactions."}],"balance_after":89602,"source":{"system":"sec-edgar","filing":"0002119908-26-000013","document":"form4a-10072026_101043.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/2119908/000211990826000013/form4a-10072026_101043.xml","form_type":"4/A","original_submission_date":"2026-10-06"}},{"id":4637417,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":29664,"kind":"person","name":"Perry Jennifer Scott","position":1,"cik":"0002119908","reported_name":"Perry Jennifer Scott","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Operating Officer"}}],"security":"Ordinary Shares","published_at":"2026-10-07T22:24:47.000Z","date":"2026-10-05","kind":"sale","planned":true,"acquired":false,"shares":30,"price":3.57,"value":107.1,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting and settlement of the RSUs. This sale is mandated by the Reporting Person's award agreement that requires the satisfaction of minimum statutory tax withholding obligations to be funded by a \"sell to cover\" transaction and does not represent a discretionary sale by the Reporting Person."},{"field":"shares","element":"transactionShares","label":"F2","text":"The original Form 4 inadvertently overstated the number of shares sold, weighted average price and the number of shares beneficially owned following the reported transactions. This amendment correctly states the number of shares sold, weighted average price and the number of shares beneficially owned following the reported transactions."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The original Form 4 inadvertently overstated the number of shares sold, weighted average price and the number of shares beneficially owned following the reported transactions. This amendment correctly states the number of shares sold, weighted average price and the number of shares beneficially owned following the reported transactions."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.56 to $3.57 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"The original Form 4 inadvertently overstated the number of shares sold, weighted average price and the number of shares beneficially owned following the reported transactions. This amendment correctly states the number of shares sold, weighted average price and the number of shares beneficially owned following the reported transactions."}],"balance_after":89928,"source":{"system":"sec-edgar","filing":"0002119908-26-000013","document":"form4a-10072026_101043.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/2119908/000211990826000013/form4a-10072026_101043.xml","form_type":"4/A","original_submission_date":"2026-10-06"}},{"id":4636254,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":29664,"kind":"person","name":"Perry Jennifer Scott","position":1,"cik":"0002119908","reported_name":"Perry Jennifer Scott","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Operating Officer"}}],"security":"Ordinary Shares","published_at":"2026-10-06T20:45:09.000Z","date":"2026-10-05","kind":"sale","planned":true,"acquired":false,"shares":326,"price":3.78,"value":1232.28,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F4","text":"This transaction was made pursuant to a Rule 10b5-1 trading plan adopted on March 27, 2025."}],"balance_after":89552,"source":{"system":"sec-edgar","filing":"0002119908-26-000011","document":"form4-10062026_041004.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/2119908/000211990826000011/form4-10062026_041004.xml","form_type":"4"}},{"id":4636253,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":29664,"kind":"person","name":"Perry Jennifer Scott","position":1,"cik":"0002119908","reported_name":"Perry Jennifer Scott","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Operating Officer"}}],"security":"Ordinary Shares","published_at":"2026-10-06T20:45:09.000Z","date":"2026-10-05","kind":"sale","planned":true,"acquired":false,"shares":80,"price":3.56,"value":284.8,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting and settlement of the RSUs. This sale is mandated by the Reporting Person's award agreement that requires the satisfaction of minimum statutory tax withholding obligations to be funded by a \"sell to cover\" transaction and does not represent a discretionary sale by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.56 to $3.57 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":89878,"source":{"system":"sec-edgar","filing":"0002119908-26-000011","document":"form4-10062026_041004.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/2119908/000211990826000011/form4-10062026_041004.xml","form_type":"4"}},{"id":4636252,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":29664,"kind":"person","name":"Perry Jennifer Scott","position":1,"cik":"0002119908","reported_name":"Perry Jennifer Scott","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Operating Officer"}}],"security":"Ordinary Shares","published_at":"2026-10-06T20:45:09.000Z","date":"2026-10-02","kind":"sale","planned":true,"acquired":false,"shares":1094,"price":3.47,"value":3796.18,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting and settlement of the RSUs. This sale is mandated by the Reporting Person's award agreement that requires the satisfaction of minimum statutory tax withholding obligations to be funded by a \"sell to cover\" transaction and does not represent a discretionary sale by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $3.41 to $3.525 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":89958,"source":{"system":"sec-edgar","filing":"0002119908-26-000011","document":"form4-10062026_041004.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/2119908/000211990826000011/form4-10062026_041004.xml","form_type":"4"}},{"id":706324,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":29664,"kind":"person","name":"Perry Jennifer Scott","position":1,"cik":"0002119908","reported_name":"Perry Jennifer Scott","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Operating Officer"}}],"security":"Employee Stock Option (right to buy)","published_at":"2026-07-17T20:15:06.000Z","date":"2026-07-15","kind":"grant","planned":false,"acquired":true,"shares":60000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option shall vest with respect to one-fourth (1/4) of the total number of shares underlying the option on July 15, 2027 and the remaining shares in 36 equal monthly installments thereafter."}],"balance_after":60000,"derivative":{"exercise_price":4.21,"expiration_date":"2036-07-15","underlying":"Ordinary Shares","underlying_shares":60000},"source":{"system":"sec-edgar","filing":"0002119908-26-000009","document":"form4-07172026_040701.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1761612/000211990826000009/form4-07172026_040701.xml","form_type":"4"}},{"id":713351,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":29664,"kind":"person","name":"Perry Jennifer Scott","position":1,"cik":"0002119908","reported_name":"Perry Jennifer Scott","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Operating Officer"}}],"security":"Ordinary Shares","published_at":"2026-07-07T21:00:16.000Z","date":"2026-07-06","kind":"sale","planned":true,"acquired":false,"shares":333,"price":4.34,"value":1445.22,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F4","text":"This transaction was made pursuant to a Rule 10b5-1 trading plan adopted on March 27, 2025."}],"balance_after":91052,"source":{"system":"sec-edgar","filing":"0002119908-26-000007","document":"form4-07072026_050711.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1761612/000211990826000007/form4-07072026_050711.xml","form_type":"4"}},{"id":713350,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":29664,"kind":"person","name":"Perry Jennifer Scott","position":1,"cik":"0002119908","reported_name":"Perry Jennifer Scott","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Operating Officer"}}],"security":"Ordinary Shares","published_at":"2026-07-07T21:00:16.000Z","date":"2026-07-06","kind":"sale","planned":true,"acquired":false,"shares":43,"price":4.31,"value":185.33,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting and settlement of the RSUs. This sale is mandated by the Reporting Person's award agreement that requires the satisfaction of minimum statutory tax withholding obligations to be funded by a \"sell to cover\" transaction and does not represent a discretionary sale by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.30 to $4.31 inclusive."}],"balance_after":91385,"source":{"system":"sec-edgar","filing":"0002119908-26-000007","document":"form4-07072026_050711.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1761612/000211990826000007/form4-07072026_050711.xml","form_type":"4"}},{"id":713349,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":29664,"kind":"person","name":"Perry Jennifer Scott","position":1,"cik":"0002119908","reported_name":"Perry Jennifer Scott","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Operating Officer"}}],"security":"Ordinary Shares","published_at":"2026-07-07T21:00:16.000Z","date":"2026-07-02","kind":"sale","planned":true,"acquired":false,"shares":1036,"price":4.27,"value":4423.72,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting and settlement of the RSUs. This sale is mandated by the Reporting Person's award agreement that requires the satisfaction of minimum statutory tax withholding obligations to be funded by a \"sell to cover\" transaction and does not represent a discretionary sale by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.26 to $4.29 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (3)."}],"balance_after":91428,"source":{"system":"sec-edgar","filing":"0002119908-26-000007","document":"form4-07072026_050711.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1761612/000211990826000007/form4-07072026_050711.xml","form_type":"4"}},{"id":814135,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":29664,"kind":"person","name":"Perry Jennifer Scott","position":1,"cik":"0002119908","reported_name":"Perry Jennifer Scott","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Operating Officer"}}],"security":"Ordinary Shares","published_at":"2026-04-06T22:30:10.000Z","date":"2026-04-06","kind":"sale","planned":true,"acquired":false,"shares":333,"price":5.04,"value":1678.32,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F3","text":"This transaction was made pursuant to a Rule 10b5-1 trading plan adopted on March 27, 2025."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $5.035 to $5.04 inclusive."}],"balance_after":92464,"source":{"system":"sec-edgar","filing":"0002119908-26-000005","document":"form4-04062026_060405.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1761612/000211990826000005/form4-04062026_060405.xml","form_type":"4"}},{"id":814134,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":29664,"kind":"person","name":"Perry Jennifer Scott","position":1,"cik":"0002119908","reported_name":"Perry Jennifer Scott","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Operating Officer"}}],"security":"Ordinary Shares","published_at":"2026-04-06T22:30:10.000Z","date":"2026-04-06","kind":"sale","planned":true,"acquired":false,"shares":37,"price":5.05,"value":186.85,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting and settlement of the RSUs. This sale is mandated by the Reporting Person's award agreement that requires the satisfaction of minimum statutory tax withholding obligations to be funded by a \"sell to cover\" transaction and does not represent a discretionary sale by the Reporting Person."}],"balance_after":92797,"source":{"system":"sec-edgar","filing":"0002119908-26-000005","document":"form4-04062026_060405.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1761612/000211990826000005/form4-04062026_060405.xml","form_type":"4"}},{"id":814133,"issuer":{"id":5993,"kind":"organization","name":"BICYCLE THERAPEUTICS PLC","symbol":"BCYC"},"owners":[{"id":29664,"kind":"person","name":"Perry Jennifer Scott","position":1,"cik":"0002119908","reported_name":"Perry Jennifer Scott","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Operating Officer"}}],"security":"Ordinary Shares","published_at":"2026-04-06T22:30:10.000Z","date":"2026-04-02","kind":"sale","planned":true,"acquired":false,"shares":1038,"price":4.91,"value":5096.58,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Represents the number of shares required to be sold to cover the statutory tax withholding obligations in connection with the vesting and settlement of the RSUs. This sale is mandated by the Reporting Person's award agreement that requires the satisfaction of minimum statutory tax withholding obligations to be funded by a \"sell to cover\" transaction and does not represent a discretionary sale by the Reporting Person."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $4.88 to $4.98 inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (2) and (4)."}],"balance_after":92834,"source":{"system":"sec-edgar","filing":"0002119908-26-000005","document":"form4-04062026_060405.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1761612/000211990826000005/form4-04062026_060405.xml","form_type":"4"}}]}