{"transactions":[{"id":705099,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2026-07-22T00:40:28.000Z","date":"2026-06-12","kind":"grant","planned":false,"acquired":true,"shares":10826,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F1","text":"This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"This Form 4 amendment is being filed solely to amend the Form 4 filed on June 16, 2026 to correct the number of options awarded to the Reporting Person on June 12, 2026."}],"balance_after":10826,"derivative":{"exercise_price":12.64,"expiration_date":"2036-06-11","underlying":"Common 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this option shall vest and become exercisable in full upon the earlier of (i) June 12, 2027 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date."}],"balance_after":9810,"derivative":{"exercise_price":12.64,"expiration_date":"2036-06-11","underlying":"Common Stock","underlying_shares":9810},"source":{"system":"sec-edgar","filing":"0001193125-26-272697","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000119312526272697/ownership.xml","form_type":"4"}},{"id":747887,"issuer":{"id":1723,"kind":"organization","name":"Stoke Therapeutics, Inc.","symbol":"STOK"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS 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These shares were sold in multiple transactions at prices ranging from $40.00 to $40.095 per share, inclusive. The reporting person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":31339,"source":{"system":"sec-edgar","filing":"0001586226-26-000002","document":"form4-03122026_080323.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1623526/000158622626000002/form4-03122026_080323.xml","form_type":"4"}},{"id":846076,"issuer":{"id":1723,"kind":"organization","name":"Stoke Therapeutics, Inc.","symbol":"STOK"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Interim Executive Chair"}}],"security":"Common Stock","published_at":"2026-03-12T20:57:26.000Z","date":"2026-03-10","kind":"exercise","planned":true,"acquired":true,"shares":3955,"price":8.33,"value":32945.15,"ownership":{"direct":true},"balance_after":35694,"source":{"system":"sec-edgar","filing":"0001586226-26-000002","document":"form4-03122026_080323.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1623526/000158622626000002/form4-03122026_080323.xml","form_type":"4"}},{"id":1013105,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-10-28T01:16:37.000Z","date":"2025-10-23","kind":"grant","planned":false,"acquired":true,"shares":53521,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares underlying this option shall vest and become exercisable in full upon the earlier of (i) October 23, 2026 or (ii) the date of the Issuer's next annual meeting of stockholders, subject to the Reporting Person's continued service on such vesting date."}],"balance_after":53521,"derivative":{"exercise_price":2.8,"expiration_date":"2035-10-22","underlying":"Common Stock","underlying_shares":53521},"source":{"system":"sec-edgar","filing":"0001193125-25-251981","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000119312525251981/ownership.xml","form_type":"4"}},{"id":1195685,"issuer":{"id":1723,"kind":"organization","name":"Stoke Therapeutics, Inc.","symbol":"STOK"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Interim Executive Chair"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-03-20T22:18:36.000Z","date":"2025-03-20","kind":"grant","planned":false,"acquired":true,"shares":122651,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests ratably as to 1/12 of the total award on the monthly anniversary of the grant date, subject to the  reporting person's continued service to the Issuer on each vesting date."}],"balance_after":122651,"derivative":{"exercise_price":8.33,"expiration_date":"2035-03-19","underlying":"Common Stock","underlying_shares":122651},"source":{"system":"sec-edgar","filing":"0001415889-25-008714","document":"form4-03202025_100333.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1623526/000141588925008714/form4-03202025_100333.xml","form_type":"4"}},{"id":1240148,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-02-27T11:01:06.000Z","date":"2025-02-24","kind":"grant","planned":false,"acquired":true,"shares":12767,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F3","text":"The exercise price of the option is $2.54 per share, representing the fair market value per share of the Issuer's Common Stock on the Repricing Date; 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All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On February 24, 2025, the Issuer's board of directors approved an option repricing (\"Repricing Date\"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This stock option award was issued pursuant to the Q32 Bio Inc. 2017 Stock Option and Grant Plan (the \"2017 Plan\") or the Q32 Bio Inc. 2024 Stock Option and Incentive Plan (the \"2024 Plan\"), as applicable, and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form 4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date."}],"balance_after":12767,"derivative":{"exercise_price":2.54,"expiration_date":"2034-03-24","underlying":"Common Stock","underlying_shares":12767},"source":{"system":"sec-edgar","filing":"0000950170-25-028265","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000095017025028265/ownership.xml","form_type":"4"}},{"id":1240147,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-02-27T11:01:06.000Z","date":"2025-02-24","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":12767,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"On February 24, 2025, the Issuer's board of directors approved an option repricing (\"Repricing Date\"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On February 24, 2025, the Issuer's board of directors approved an option repricing (\"Repricing Date\"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This stock option award was issued pursuant to the Q32 Bio Inc. 2017 Stock Option and Grant Plan (the \"2017 Plan\") or the Q32 Bio Inc. 2024 Stock Option and Incentive Plan (the \"2024 Plan\"), as applicable, and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form 4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date."}],"balance_after":0,"derivative":{"exercise_price":16.82,"expiration_date":"2034-03-24","underlying":"Common Stock","underlying_shares":12767},"source":{"system":"sec-edgar","filing":"0000950170-25-028265","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000095017025028265/ownership.xml","form_type":"4"}},{"id":1240146,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-02-27T11:01:06.000Z","date":"2025-02-24","kind":"grant","planned":false,"acquired":true,"shares":25674,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F3","text":"The exercise price of the option is $2.54 per share, representing the fair market value per share of the Issuer's Common Stock on the Repricing Date; provided that in the event (i) the option is exercised prior to the one-year anniversary of the Repricing Date, (ii) the Reporting Person's employment is terminated by the Company prior to the one-year anniversary of the Repricing Date due to Cause (as defined in the 2024 Plan) or (iii) the Reporting Person resigns for any reason prior to the one-year anniversary of the Repricing Date, the exercise price will be increased to the exercise price of the cancelled option in exchange for which this option was granted."},{"field":"kind","element":"transactionCoding","label":"F1","text":"On February 24, 2025, the Issuer's board of directors approved an option repricing (\"Repricing Date\"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On February 24, 2025, the Issuer's board of directors approved an option repricing (\"Repricing Date\"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This stock option award was issued pursuant to the Q32 Bio Inc. 2017 Stock Option and Grant Plan (the \"2017 Plan\") or the Q32 Bio Inc. 2024 Stock Option and Incentive Plan (the \"2024 Plan\"), as applicable, and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form 4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date."}],"balance_after":25674,"derivative":{"exercise_price":2.54,"expiration_date":"2026-04-22","underlying":"Common Stock","underlying_shares":25674},"source":{"system":"sec-edgar","filing":"0000950170-25-028265","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000095017025028265/ownership.xml","form_type":"4"}},{"id":1240145,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2025-02-27T11:01:06.000Z","date":"2025-02-24","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":25674,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"On February 24, 2025, the Issuer's board of directors approved an option repricing (\"Repricing Date\"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On February 24, 2025, the Issuer's board of directors approved an option repricing (\"Repricing Date\"). All of the other terms of the options remain unchanged. Such transactions were exempt pursuant to Rule 16b-6(d) and Rule 16b-3 of the Exchange Act, as applicable."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This stock option award was issued pursuant to the Q32 Bio Inc. 2017 Stock Option and Grant Plan (the \"2017 Plan\") or the Q32 Bio Inc. 2024 Stock Option and Incentive Plan (the \"2024 Plan\"), as applicable, and becomes exercisable in accordance with the vesting schedule specified in the award agreement and as previously reported on applicable Form 4, subject to the Reporting Person's continued service with the Issuer as of the applicable vesting date."}],"balance_after":0,"derivative":{"exercise_price":7.09,"expiration_date":"2026-04-22","underlying":"Common Stock","underlying_shares":25674},"source":{"system":"sec-edgar","filing":"0000950170-25-028265","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000095017025028265/ownership.xml","form_type":"4"}},{"id":1433356,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Restricted Stock Units","published_at":"2024-08-14T20:05:05.000Z","date":"2024-03-25","kind":"exercise","planned":false,"acquired":false,"shares":1095,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each restricted stock unit represents a contingent right to receive one share of Issuer Common Stock."},{"field":"shares","element":"transactionShares","label":"F2","text":"The Issuer effected a 1-for-18 reverse stock split of its Common Stock on March 25, 2024. The amounts reported on this Form 4 have been adjusted to reflect the reverse stock split."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"The restricted stock units vested in three equal installments, with the final installment vested on March 25, 2024. The restricted stock units had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F4","text":"The restricted stock units vested in three equal installments, with the final installment vested on March 25, 2024. 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converted into the right to receive (x) an amount in cash, without interest and less any applicable tax withholdings, equal to the product of (A) the total number of Shares subject to such option immediately prior to the Effective Time multiplied by (B) the excess, if any, of the Cash Consideration over the applicable exercise price per Share under such option and (y) one CVR for each Share subject to such option immediately prior to the Effective Time (without regard to vesting)."}],"balance_after":0,"derivative":{"exercise_price":4.21,"expiration_date":"2032-06-22","underlying":"Common Stock","underlying_shares":16000},"source":{"system":"sec-edgar","filing":"0001104659-22-124141","document":"tm2231851-8_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1722271/000110465922124141/tm2231851-8_4seq1.xml","form_type":"4"}},{"id":2098380,"issuer":{"id":11574,"kind":"organization","name":"Akouos, 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non-tradable contingent value right (\"CVR\") per Share, which represents the contractual right to receive contingent payments of up to $3.00 per CVR, net to the stockholder in cash, without interest and less any applicable tax withholding, upon the achievement of certain specified milestones in accordance with the terms and subject to the conditions of a Contingent Value Rights Agreement, dated as of November 30, 2022, by and among Parent, Merger Sub, Computershare Inc. and Computershare Trust Company, N.A."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Pursuant to the terms of that certain Agreement and Plan of Merger (the \"Merger Agreement\"), by and among the Issuer, Eli Lilly and Company (\"Parent\") and Kearny Acquisition Corporation (\"Merger Sub\"), dated as of October 17, 2022, these shares of common stock, par value $0.0001 per share, of the Issuer (\"Shares\") were tendered prior to the Expiration Date (as defined in the Merger Agreement) and disposed of at the Acceptance Time (as defined in the Merger Agreement) in exchange for (i) $12.50 per Share, net to the stockholder in cash, without interest (the \"Cash Consideration\") and less any applicable tax withholding, plus [Continued on Note 2]"},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"[Continuation of Note 1] (ii) one non-tradable contingent value right (\"CVR\") per Share, which represents the contractual right to receive contingent payments of up to $3.00 per CVR, net to the stockholder in cash, without interest and less any applicable tax withholding, upon the achievement of certain specified milestones in accordance with the terms and subject to the conditions of a Contingent Value Rights Agreement, dated as of November 30, 2022, by and among Parent, Merger Sub, Computershare Inc. and Computershare Trust Company, 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The shares underlying the option will fully vest on the earlier of (i) June 23, 2023 and (ii) the date of the Issuer's 2023 annual meeting of stockholders."}],"balance_after":16000,"derivative":{"exercise_price":4.21,"expiration_date":"2032-06-22","underlying":"Common Stock","underlying_shares":16000},"source":{"system":"sec-edgar","filing":"0001104659-22-074830","document":"tm2219359-4_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1722271/000110465922074830/tm2219359-4_4seq1.xml","form_type":"4"}},{"id":2239116,"issuer":{"id":1723,"kind":"organization","name":"Stoke Therapeutics, Inc.","symbol":"STOK"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Director Stock Option (Right to Buy)","published_at":"2022-06-08T21:00:26.000Z","date":"2022-06-07","kind":"grant","acquired":true,"shares":21000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option shall vest on June 7, 2023 or, if earlier, the next annual meeting of the issuer's stockholders, subject to the reporting holder's continued service on such vesting date."}],"balance_after":21000,"derivative":{"exercise_price":12.96,"expiration_date":"2032-06-06","underlying":"Common Stock","underlying_shares":21000},"source":{"system":"sec-edgar","filing":"0001209191-22-035075","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1623526/000120919122035075/doc4.xml","form_type":"4"}},{"id":2368338,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Restricted Stock Units","published_at":"2022-02-28T21:05:15.000Z","date":"2022-02-24","kind":"grant","acquired":true,"shares":58000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F2","text":"Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.  The restricted stock units have no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The restricted stock units will vest and settle as to one third of the restricted stock units on each of the first three anniversaries of January 1, 2022 so that such RSUs will become fully vested on January 1, 2025."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F2","text":"Each restricted stock unit represents a contingent right to receive one share of Issuer common stock.  The restricted stock units have no expiration date."}],"balance_after":58000,"derivative":{"underlying":"Common Stock","underlying_shares":58000},"source":{"system":"sec-edgar","filing":"0000899243-22-008059","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924322008059/doc4.xml","form_type":"4"}},{"id":2368337,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2022-02-28T21:05:15.000Z","date":"2022-02-24","kind":"grant","acquired":true,"shares":350000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in 48 substantially equal monthly installments on the first day of each calendar month following January 1, 2022."}],"balance_after":350000,"derivative":{"exercise_price":2.71,"expiration_date":"2032-02-24","underlying":"Common Stock","underlying_shares":350000},"source":{"system":"sec-edgar","filing":"0000899243-22-008059","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924322008059/doc4.xml","form_type":"4"}},{"id":2436496,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Restricted Stock Units","published_at":"2022-01-12T21:05:12.000Z","date":"2022-01-01","kind":"exercise","acquired":false,"shares":13860,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each Restricted Stock Unit (\"RSU\") represents a contingent right to receive one share of Issuer common stock."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"The RSUs have vested and settled or will vest and settle, as applicable, as to one third of the restricted stock units on each of the first three anniversaries of January 1, 2021 so that such RSUs will become fully vested on January 1, 2024.  The RSUs do not have an expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F4","text":"The RSUs have vested and settled or will vest and settle, as applicable, as to one third of the restricted stock units on each of the first three anniversaries of January 1, 2021 so that such RSUs will become fully vested on January 1, 2024.  The RSUs do not have an expiration date."}],"balance_after":28140,"derivative":{"underlying":"Common Stock","underlying_shares":13860},"source":{"system":"sec-edgar","filing":"0000899243-22-001743","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924322001743/doc4.xml","form_type":"4"}},{"id":2436495,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2022-01-12T21:05:12.000Z","date":"2022-01-05","kind":"sale","acquired":false,"shares":5354,"price":3.7802,"value":20239.1908,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F2","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 instruction solely with the intent to cover withholding taxes in connection with the settlement of RSUs."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported is a weighted average price.  The securities were sold in multiple transactions at per share prices ranging from $3.78 to $3.80.  The Reporting Person undertakes to provide upon request the SEC staff, the Issuer, or any shareholder of the Issuer, full information regarding the number of securities sold at each separate price within the range set forth in this footnote 3."}],"balance_after":86011,"source":{"system":"sec-edgar","filing":"0000899243-22-001743","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924322001743/doc4.xml","form_type":"4"}},{"id":2436494,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2022-01-12T21:05:12.000Z","date":"2022-01-01","kind":"exercise","acquired":true,"shares":13860,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each Restricted Stock Unit (\"RSU\") represents a contingent right to receive one share of Issuer common stock."}],"balance_after":91365,"source":{"system":"sec-edgar","filing":"0000899243-22-001743","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924322001743/doc4.xml","form_type":"4"}},{"id":2654766,"issuer":{"id":1723,"kind":"organization","name":"Stoke Therapeutics, Inc.","symbol":"STOK"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Director Stock Option (Right to Buy)","published_at":"2021-06-25T21:04:16.000Z","date":"2021-06-08","kind":"grant","acquired":true,"shares":11650,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option shall fully vest on June 8, 2022 or, if earlier, the next annual meeting of the issuer's stockholders, subject to the reporting holder's  continued service on such  vesting date."}],"balance_after":11650,"derivative":{"exercise_price":40.37,"expiration_date":"2031-06-07","underlying":"Common Stock","underlying_shares":11650},"source":{"system":"sec-edgar","filing":"0001209191-21-043340","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1623526/000120919121043340/doc4.xml","form_type":"4"}},{"id":2654827,"issuer":{"id":11574,"kind":"organization","name":"Akouos, Inc.","symbol":"AKUS"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2021-06-25T16:34:30.000Z","date":"2021-06-24","kind":"grant","acquired":true,"shares":16000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option was granted on June 24, 2021. The shares underlying the option will fully vest on the earlier of (i) June 24, 2022 and (ii) the date of the Issuer's 2022 annual meeting of stockholders."}],"balance_after":16000,"derivative":{"exercise_price":13.39,"expiration_date":"2031-06-23","underlying":"Common Stock","underlying_shares":16000},"source":{"system":"sec-edgar","filing":"0001104659-21-085755","document":"tm2120686-1_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1722271/000110465921085755/tm2120686-1_4seq1.xml","form_type":"4"}},{"id":2839341,"issuer":{"id":1723,"kind":"organization","name":"Stoke Therapeutics, Inc.","symbol":"STOK"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Director Stock Option (Right to 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These shares were sold in multiple transactions at prices ranging from $47.47 to $47.71 per share, inclusive.  The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001209191-20-060549","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1623526/000120919120060549/doc4.xml","form_type":"4"}},{"id":2966183,"issuer":{"id":1723,"kind":"organization","name":"Stoke Therapeutics, Inc.","symbol":"STOK"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2020-11-25T22:09:24.000Z","date":"2020-11-23","kind":"sale","acquired":false,"shares":5294,"price":46.8472,"value":248009.0768,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The reported price in Column 4 is a weighted average price.  These shares were sold in multiple transactions at prices ranging from $46.42 to $47.35 per share, inclusive.  The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":210,"source":{"system":"sec-edgar","filing":"0001209191-20-060549","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1623526/000120919120060549/doc4.xml","form_type":"4"}},{"id":2966182,"issuer":{"id":1723,"kind":"organization","name":"Stoke Therapeutics, Inc.","symbol":"STOK"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2020-11-25T22:09:24.000Z","date":"2020-11-23","kind":"sale","acquired":false,"shares":10196,"price":45.971,"value":468720.316,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The reported price in Column 4 is a weighted average price.  These shares were sold in multiple transactions at prices ranging from $45.42 to $46.41 per share, inclusive.  The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":5504,"source":{"system":"sec-edgar","filing":"0001209191-20-060549","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1623526/000120919120060549/doc4.xml","form_type":"4"}},{"id":2966181,"issuer":{"id":1723,"kind":"organization","name":"Stoke Therapeutics, Inc.","symbol":"STOK"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2020-11-25T22:09:24.000Z","date":"2020-11-23","kind":"sale","acquired":false,"shares":4300,"price":45.0787,"value":193838.41,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sales reported on this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The reported price in Column 4 is a weighted average price.  These shares were sold in multiple transactions at prices ranging from $44.41 to $45.40 per share, inclusive.  The reporting person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":15700,"source":{"system":"sec-edgar","filing":"0001209191-20-060549","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1623526/000120919120060549/doc4.xml","form_type":"4"}},{"id":2966180,"issuer":{"id":1723,"kind":"organization","name":"Stoke Therapeutics, Inc.","symbol":"STOK"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2020-11-25T22:09:24.000Z","date":"2020-11-23","kind":"exercise","acquired":true,"shares":20000,"price":2.19,"value":43800.0,"ownership":{"direct":true},"balance_after":20000,"source":{"system":"sec-edgar","filing":"0001209191-20-060549","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1623526/000120919120060549/doc4.xml","form_type":"4"}},{"id":3120385,"issuer":{"id":1723,"kind":"organization","name":"Stoke Therapeutics, Inc.","symbol":"STOK"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Director Stock Option (Right to Buy)","published_at":"2020-06-05T21:32:52.000Z","date":"2020-06-03","kind":"grant","acquired":true,"shares":14777,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option shall fully vest on June 3, 2021 or, if earlier, the next annual meeting of the issuer's stockholders, subject to the reporting holder's  continued service on such  vesting date."}],"balance_after":14777,"derivative":{"exercise_price":26.53,"expiration_date":"2030-06-02","underlying":"Common Stock","underlying_shares":14777},"source":{"system":"sec-edgar","filing":"0001209191-20-034737","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1623526/000120919120034737/doc4.xml","form_type":"4"}},{"id":3288105,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2020-02-05T21:05:24.000Z","date":"2020-02-03","kind":"sale","acquired":false,"shares":12500,"price":16.1617,"value":202021.25,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported is a weighted average price.  The shares were sold in multiple transactions at per share prices ranging from $16.0400 to $16.3700.  The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":77505,"source":{"system":"sec-edgar","filing":"0000899243-20-003246","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924320003246/doc4.xml","form_type":"4"}},{"id":3321458,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2020-01-03T22:36:25.000Z","date":"2020-01-02","kind":"sale","acquired":false,"shares":12500,"price":20.4953,"value":256191.25,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported is a weighted average price.  The shares were sold in multiple transactions at per share prices ranging from $20.3800 to $20.7000.  The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":90005,"source":{"system":"sec-edgar","filing":"0000899243-20-000316","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924320000316/doc4.xml","form_type":"4"}},{"id":3342037,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2019-12-13T21:07:17.000Z","date":"2019-12-11","kind":"grant","acquired":true,"shares":358000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in 48 equal monthly installments on the first day of each calendar month following January 1, 2020."}],"balance_after":358000,"derivative":{"exercise_price":19.92,"expiration_date":"2029-12-11","underlying":"Common Stock","underlying_shares":358000},"source":{"system":"sec-edgar","filing":"0000899243-19-029158","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924319029158/doc4.xml","form_type":"4"}},{"id":3353663,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-12-03T21:06:24.000Z","date":"2019-12-02","kind":"sale","acquired":false,"shares":12500,"price":16.2541,"value":203176.25,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported is a weighted average price.  The shares were sold in multiple transactions at per share prices ranging from $16.02 to $16.39.  The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":102505,"source":{"system":"sec-edgar","filing":"0000899243-19-028394","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924319028394/doc4.xml","form_type":"4"}},{"id":3353662,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-12-03T21:06:24.000Z","date":"2019-11-29","kind":"sale","acquired":false,"shares":12500,"price":16.0447,"value":200558.75,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported is a weighted average price.  The shares were sold in multiple transactions at per share prices ranging from $16.00 to $16.1550.  The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":115005,"source":{"system":"sec-edgar","filing":"0000899243-19-028394","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924319028394/doc4.xml","form_type":"4"}},{"id":3400469,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-10-02T20:08:13.000Z","date":"2019-10-01","kind":"sale","acquired":false,"shares":100,"price":18.23,"value":1823.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018."}],"balance_after":127505,"source":{"system":"sec-edgar","filing":"0000899243-19-024657","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924319024657/doc4.xml","form_type":"4"}},{"id":3400468,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-10-02T20:08:13.000Z","date":"2019-10-01","kind":"sale","acquired":false,"shares":12400,"price":17.3907,"value":215644.68,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported is a weighted average price.  The shares were sold in multiple transactions at per share prices ranging from $17.07 to $18.02.  The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":127605,"source":{"system":"sec-edgar","filing":"0000899243-19-024657","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924319024657/doc4.xml","form_type":"4"}},{"id":3416258,"issuer":{"id":1723,"kind":"organization","name":"Stoke Therapeutics, Inc.","symbol":"STOK"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Director Stock Option (Right to Buy)","published_at":"2019-09-13T00:07:32.000Z","date":"2019-09-10","kind":"grant","acquired":true,"shares":14777,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vests 100% and becomes exercisable on June 21, 2020, subject to reporting person's continued service through such vesting date."}],"balance_after":14777,"derivative":{"exercise_price":28.8,"expiration_date":"2029-09-09","underlying":"Common Stock","underlying_shares":14777},"source":{"system":"sec-edgar","filing":"0001567619-19-018222","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1623526/000156761919018222/doc1.xml","form_type":"4"}},{"id":3421422,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-09-05T20:39:00.000Z","date":"2019-09-03","kind":"sale","acquired":false,"shares":12500,"price":18.7456,"value":234320.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported is a weighted average price.  The shares were sold in multiple transactions at per share prices ranging from $18.30 to $19.06.  The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":140005,"source":{"system":"sec-edgar","filing":"0000899243-19-022839","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924319022839/doc4.xml","form_type":"4"}},{"id":3446604,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-08-05T20:15:24.000Z","date":"2019-08-01","kind":"sale","acquired":false,"shares":12500,"price":17.3689,"value":217111.25,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported is a weighted average price. 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The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":152505,"source":{"system":"sec-edgar","filing":"0000899243-19-020990","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924319020990/doc4.xml","form_type":"4"}},{"id":3467358,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-07-03T20:30:19.000Z","date":"2019-07-01","kind":"sale","acquired":false,"shares":12500,"price":18.984,"value":237300.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported is a weighted average price. 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The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":165005,"source":{"system":"sec-edgar","filing":"0000899243-19-019172","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924319019172/doc4.xml","form_type":"4"}},{"id":3500063,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Common Stock","published_at":"2019-06-05T22:10:16.000Z","date":"2019-06-03","kind":"sale","acquired":false,"shares":12500,"price":19.861,"value":248262.5,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported in the Form 4 was effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on November 20, 2018."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported is a weighted average price.  The shares were sold in multiple transactions at per share prices ranging from $19.43 to $20.42.  The Reporting Person undertakes to provide upon request to the SEC staff, the Issuer, or any stockholder of the Issuer, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."}],"balance_after":177505,"source":{"system":"sec-edgar","filing":"0000899243-19-015645","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924319015645/doc4.xml","form_type":"4"}},{"id":3726221,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Employee stock option","published_at":"2018-12-18T22:21:49.000Z","date":"2018-12-14","kind":"grant","acquired":true,"shares":203000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in 48 equal monthly installments on the first day of each calendar month following January 1, 2019."}],"balance_after":203000,"derivative":{"exercise_price":24.28,"expiration_date":"2028-12-14","underlying":"Common Stock","underlying_shares":203000},"source":{"system":"sec-edgar","filing":"0000899243-18-031342","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924318031342/doc4.xml","form_type":"4"}},{"id":3979264,"issuer":{"id":5594,"kind":"organization","name":"Q32 Bio Inc.","symbol":"QTTB"},"owners":[{"id":29273,"kind":"person","name":"TZIANABOS ARTHUR","position":1,"cik":"0001586226","reported_name":"TZIANABOS ARTHUR","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President & CEO"}}],"security":"Employee stock option","published_at":"2018-03-29T23:31:09.000Z","date":"2018-03-27","kind":"grant","acquired":true,"shares":92376,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in 48 equal monthly installments on the first day of each calendar month following March 27, 2018."}],"balance_after":92376,"derivative":{"exercise_price":16,"expiration_date":"2028-03-27","underlying":"Common Stock","underlying_shares":92376},"source":{"system":"sec-edgar","filing":"0000899243-18-008931","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1586226/000089924318008931/doc4.xml","form_type":"4"}}]}