{"transactions":[{"id":700608,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Restricted Stock Units","published_at":"2026-07-31T00:32:28.000Z","date":"2026-07-28","kind":"exercise","planned":false,"acquired":false,"shares":57000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"security","element":"securityTitle","label":"F2","text":"These RSUs reported in Table II were granted to the Reporting Person on July 28, 2025 as part of an aggregate award of 95,000 RSUs and initially reported in Table I of the Form 4 filed on July 30, 2025, because they were solely settleable in shares at the time of grant. These RSUs are being moved to Table II as of this Form 4."},{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each restricted stock unit (\"RSU\") represents the contingent right to receive one share of the Issuer's Ordinary Shares upon vesting."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"These RSUs reported in Table II are fully vested as of July 28, 2026 (the one-year anniversary of the grant date). The remainder of the 95,000 RSUs reported in Table I (38,000 RSUs) are subject to vesting."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"These RSUs reported in Table II are fully vested as of July 28, 2026 (the one-year anniversary of the grant date). The remainder of the 95,000 RSUs reported in Table I (38,000 RSUs) are subject to vesting."}],"balance_after":0,"derivative":{"underlying":"Ordinary Shares","underlying_shares":57000},"source":{"system":"sec-edgar","filing":"0000905148-26-003413","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000090514826003413/form4.xml","form_type":"4"}},{"id":700607,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per 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Shares","underlying_shares":230000},"source":{"system":"sec-edgar","filing":"0000905148-26-001178","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000090514826001178/form4.xml","form_type":"4"}},{"id":1079060,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2025-07-30T21:51:26.000Z","date":"2025-07-28","kind":"grant","planned":false,"acquired":true,"shares":95000,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":97205,"source":{"system":"sec-edgar","filing":"0000905148-25-002658","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000090514825002658/form4.xml","form_type":"4"}},{"id":1217296,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-03-07T21:37:59.000Z","date":"2025-03-05","kind":"grant","planned":false,"acquired":true,"shares":107500,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 5, 2026, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":107500,"derivative":{"exercise_price":14.95,"expiration_date":"2035-03-05","underlying":"Ordinary Shares","underlying_shares":107500},"source":{"system":"sec-edgar","filing":"0000905148-25-000886","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000090514825000886/form4.xml","form_type":"4"}},{"id":1267201,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2025-02-14T23:34:49.000Z","date":"2020-04-08","kind":"other","planned":false,"acquired":false,"shares":995,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Represents shares transferred to the Reporting Person's former spouse in connection with a divorce proceeding."}],"balance_after":2205,"source":{"system":"sec-edgar","filing":"0000905148-25-000708","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000090514825000708/form4.xml","form_type":"4"}},{"id":1609895,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2024-03-01T02:07:04.000Z","date":"2024-02-27","kind":"grant","planned":false,"acquired":true,"shares":85000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 27, 2025, and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":85000,"derivative":{"exercise_price":30.3,"expiration_date":"2034-02-27","underlying":"Ordinary Shares","underlying_shares":85000},"source":{"system":"sec-edgar","filing":"0000905148-24-000838","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000090514824000838/form4.xml","form_type":"4"}},{"id":1669626,"issuer":{"id":94695,"kind":"organization","name":"Rain Oncology Inc.","symbol":"RAIN"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2024-01-26T16:47:08.000Z","date":"2024-01-26","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":20000,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."}],"balance_after":0,"derivative":{"exercise_price":2.44,"underlying":"Common Stock","underlying_shares":20000},"source":{"system":"sec-edgar","filing":"0001999371-24-000972","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1724979/000199937124000972/ownership.xml","form_type":"4"}},{"id":1669625,"issuer":{"id":94695,"kind":"organization","name":"Rain Oncology Inc.","symbol":"RAIN"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2024-01-26T16:47:08.000Z","date":"2024-01-26","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":35000,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."}],"balance_after":0,"derivative":{"exercise_price":1.21,"underlying":"Common Stock","underlying_shares":35000},"source":{"system":"sec-edgar","filing":"0001999371-24-000972","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1724979/000199937124000972/ownership.xml","form_type":"4"}},{"id":1669624,"issuer":{"id":94695,"kind":"organization","name":"Rain Oncology Inc.","symbol":"RAIN"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2024-01-26T16:47:08.000Z","date":"2024-01-26","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":42596,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."}],"balance_after":0,"derivative":{"exercise_price":3.13,"underlying":"Common Stock","underlying_shares":42596},"source":{"system":"sec-edgar","filing":"0001999371-24-000972","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1724979/000199937124000972/ownership.xml","form_type":"4"}},{"id":1669623,"issuer":{"id":94695,"kind":"organization","name":"Rain Oncology Inc.","symbol":"RAIN"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2024-01-26T16:47:08.000Z","date":"2024-01-26","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":13890,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"This Form 4 reports securities disposed of pursuant to the terms of the Merger Agreement entered into by and among the Issuer, Pathos AI, Inc. (\"Parent\") and WK Merger Sub, Inc., a wholly owned subsidiary of Parent (\"Merger Sub\"), dated as of December 13, 2023 (the \"Merger Agreement\"), pursuant to which Merger Sub completed a tender offer for all of the shares of common stock of the Issuer (each, a \"Share\") and thereafter merged with and into the Issuer effective as of January 26, 2024 (the \"Effective Time\"). Pursuant to the terms of the Merger Agreement, at the Effective Time, each option to purchase Shares granted under the Issuer's Amended and Restated 2018 Stock Option/Stock Issuance Plan or the Issuer's 2021 Equity Incentive Plan, pursuant to any inducement award or otherwise that was outstanding immediately prior to the Effective Time was cancelled for no consideration."}],"balance_after":0,"derivative":{"exercise_price":3.95,"underlying":"Common Stock","underlying_shares":13890},"source":{"system":"sec-edgar","filing":"0001999371-24-000972","document":"ownership.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1724979/000199937124000972/ownership.xml","form_type":"4"}},{"id":1809956,"issuer":{"id":94695,"kind":"organization","name":"Rain Oncology Inc.","symbol":"RAIN"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2023-08-11T21:11:21.000Z","date":"2023-08-09","kind":"grant","planned":false,"acquired":true,"shares":35000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option represents a right to purchase a total of 35,000 shares of the Issuer's common stock, which will vest in full on the date of the 2024 Annual Meeting of Stockholders of the Issuer, subject to the Reporting Person's continued service to the Issuer."}],"balance_after":35000,"derivative":{"exercise_price":1.21,"expiration_date":"2033-08-09","underlying":"Common Stock","underlying_shares":35000},"source":{"system":"sec-edgar","filing":"0001104659-23-090701","document":"tm2323614-6_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1724979/000110465923090701/tm2323614-6_4seq1.xml","form_type":"4"}},{"id":1888889,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2023-05-18T01:53:35.000Z","date":"2023-05-17","kind":"exercise","planned":true,"acquired":false,"shares":50000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"All shares subject to the option have fully vested."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F7","text":"The Reporting Person holds options that give him the right to acquire an aggregate of 806,837 shares at exercise prices ranging from $12.15 to $52.97, of which 638,253 are currently exercisable, and 168,584 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to the Court Order."}],"balance_after":0,"derivative":{"exercise_price":22.85,"expiration_date":"2025-03-11","underlying":"Ordinary Shares","underlying_shares":50000},"source":{"system":"sec-edgar","filing":"0001140361-23-025342","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":9,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036123025342/form4.xml","form_type":"4"}},{"id":1888888,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2023-05-18T01:53:35.000Z","date":"2023-05-17","kind":"exercise","planned":true,"acquired":false,"shares":45000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"All shares subject to the option have fully vested."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F7","text":"The Reporting Person holds options that give him the right to acquire an aggregate of 806,837 shares at exercise prices ranging from $12.15 to $52.97, of which 638,253 are currently exercisable, and 168,584 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to the Court Order."}],"balance_after":0,"derivative":{"exercise_price":29.81,"expiration_date":"2024-02-04","underlying":"Ordinary Shares","underlying_shares":45000},"source":{"system":"sec-edgar","filing":"0001140361-23-025342","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036123025342/form4.xml","form_type":"4"}},{"id":1888887,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-05-18T01:53:35.000Z","date":"2023-05-17","kind":"sale","planned":true,"acquired":false,"shares":100,"price":76.04,"value":7604.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on January 10, 2023 in connection with a court stipulation and order regarding the separation of assets (\"Court Order\") in accordance with a divorce settlement agreement."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0001140361-23-025342","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036123025342/form4.xml","form_type":"4"}},{"id":1888886,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-05-18T01:53:35.000Z","date":"2023-05-17","kind":"sale","planned":true,"acquired":false,"shares":9215,"price":75.4429,"value":695206.3235,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on January 10, 2023 in connection with a court stipulation and order regarding the separation of assets (\"Court Order\") in accordance with a divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F5","text":"The transaction was executed in multiple trades in prices ranging from $75.04 to $76.025, inclusive."}],"balance_after":3300,"source":{"system":"sec-edgar","filing":"0001140361-23-025342","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036123025342/form4.xml","form_type":"4"}},{"id":1888885,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-05-18T01:53:35.000Z","date":"2023-05-17","kind":"sale","planned":true,"acquired":false,"shares":37044,"price":74.5458,"value":2761474.6152,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on January 10, 2023 in connection with a court stipulation and order regarding the separation of assets (\"Court Order\") in accordance with a divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The transaction was executed in multiple trades in prices ranging from $74.03 to $75.02, inclusive."}],"balance_after":12515,"source":{"system":"sec-edgar","filing":"0001140361-23-025342","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036123025342/form4.xml","form_type":"4"}},{"id":1888884,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-05-18T01:53:35.000Z","date":"2023-05-17","kind":"sale","planned":true,"acquired":false,"shares":34640,"price":73.5367,"value":2547311.288,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on January 10, 2023 in connection with a court stipulation and order regarding the separation of assets (\"Court Order\") in accordance with a divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $73.03 to $74.025, inclusive."}],"balance_after":49559,"source":{"system":"sec-edgar","filing":"0001140361-23-025342","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036123025342/form4.xml","form_type":"4"}},{"id":1888883,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-05-18T01:53:35.000Z","date":"2023-05-17","kind":"sale","planned":true,"acquired":false,"shares":14001,"price":72.6609,"value":1017325.2609,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person on January 10, 2023 in connection with a court stipulation and order regarding the separation of assets (\"Court Order\") in accordance with a divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $72.03 to $73.02, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the ranges set forth in footnotes 2 through 5 of this Form 4."}],"balance_after":84199,"source":{"system":"sec-edgar","filing":"0001140361-23-025342","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036123025342/form4.xml","form_type":"4"}},{"id":1888882,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-05-18T01:53:35.000Z","date":"2023-05-17","kind":"exercise","planned":true,"acquired":true,"shares":50000,"price":22.85,"value":1142500.0,"ownership":{"direct":true},"balance_after":98200,"source":{"system":"sec-edgar","filing":"0001140361-23-025342","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036123025342/form4.xml","form_type":"4"}},{"id":1888881,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-05-18T01:53:35.000Z","date":"2023-05-17","kind":"exercise","planned":true,"acquired":true,"shares":45000,"price":29.81,"value":1341450.0,"ownership":{"direct":true},"balance_after":48200,"source":{"system":"sec-edgar","filing":"0001140361-23-025342","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036123025342/form4.xml","form_type":"4"}},{"id":1946786,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2023-03-18T01:31:45.000Z","date":"2023-03-15","kind":"exercise","acquired":false,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"The option was granted on April 1, 2013 and all shares subject to the option were fully vested and exercisable. The option will expire in approximately one month and be forfeited to the extent it is not exercised on or prior to March 31, 2023."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F5","text":"The Reporting Person holds options that give him the right to acquire an aggregate of 901,837 shares at exercise prices ranging from $6.73 to $52.97, of which 721,837 are currently exercisable, and 180,000 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to the Court Order."}],"balance_after":0,"derivative":{"exercise_price":6.73,"expiration_date":"2023-03-31","underlying":"Ordinary Shares","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001567619-23-005291","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923005291/doc1.xml","form_type":"4"}},{"id":1946785,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-03-18T01:31:45.000Z","date":"2023-03-15","kind":"sale","acquired":false,"shares":5198,"price":48.6781,"value":253028.7638,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and order regarding the separation of assets (\"Court Order\") in accordance with a divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $48.43 to $49.03, inclusive."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0001567619-23-005291","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923005291/doc1.xml","form_type":"4"}},{"id":1946784,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-03-18T01:31:45.000Z","date":"2023-03-15","kind":"sale","acquired":false,"shares":4802,"price":48.1644,"value":231285.4488,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and order regarding the separation of assets (\"Court Order\") in accordance with a divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $47.43 to $48.405, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in footnotes 2 through 3 of this Form 4."}],"balance_after":8398,"source":{"system":"sec-edgar","filing":"0001567619-23-005291","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923005291/doc1.xml","form_type":"4"}},{"id":1946783,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-03-18T01:31:45.000Z","date":"2023-03-15","kind":"exercise","acquired":true,"shares":10000,"price":6.73,"value":67300.0,"ownership":{"direct":true},"balance_after":13200,"source":{"system":"sec-edgar","filing":"0001567619-23-005291","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923005291/doc1.xml","form_type":"4"}},{"id":1973000,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2023-03-04T02:30:45.000Z","date":"2023-03-02","kind":"grant","acquired":true,"shares":48000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on March 2, 2024 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"The Reporting Person holds options that give him the right to acquire an aggregate of 911,837 shares at exercise prices ranging from $6.73 to $52.97, of which 731,837 are currently exercisable, and 180,000 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to an order regarding the separation of assets in accordance with a divorce settlement agreement."}],"balance_after":48000,"derivative":{"exercise_price":52.97,"expiration_date":"2033-03-02","underlying":"Ordinary Shares","underlying_shares":48000},"source":{"system":"sec-edgar","filing":"0001140361-23-010183","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036123010183/form4.xml","form_type":"4"}},{"id":2007409,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2023-02-18T02:30:47.000Z","date":"2023-02-15","kind":"exercise","acquired":false,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"The option was granted on April 1, 2013 and all shares subject to the option were fully vested and exercisable. The option will expire in approximately two months and be forfeited to the extent it is not exercised on or prior to March 31, 2023."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F5","text":"The Reporting Person holds options that give him the right to acquire an aggregate of 863,837 shares at exercise prices ranging from $6.73 to $32.45, of which 704,669 are currently exercisable, and 159,168 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to the Court Order."}],"balance_after":10000,"derivative":{"exercise_price":6.73,"expiration_date":"2023-03-31","underlying":"Ordinary Shares","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001567619-23-003363","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923003363/doc1.xml","form_type":"4"}},{"id":2007408,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-02-18T02:30:47.000Z","date":"2023-02-15","kind":"sale","acquired":false,"shares":664,"price":53.8715,"value":35770.676,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and order regarding the separation of assets (\"Court Order\") in accordance with a divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $53.87 to $53.88, inclusive."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0001567619-23-003363","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923003363/doc1.xml","form_type":"4"}},{"id":2007407,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-02-18T02:30:47.000Z","date":"2023-02-15","kind":"sale","acquired":false,"shares":9336,"price":53.3019,"value":497626.5384,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and order regarding the separation of assets (\"Court Order\") in accordance with a divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $52.835 to $53.83, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in footnotes 2 through 3 of this Form 4."}],"balance_after":3864,"source":{"system":"sec-edgar","filing":"0001567619-23-003363","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923003363/doc1.xml","form_type":"4"}},{"id":2007406,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-02-18T02:30:47.000Z","date":"2023-02-15","kind":"exercise","acquired":true,"shares":10000,"price":6.73,"value":67300.0,"ownership":{"direct":true},"balance_after":13200,"source":{"system":"sec-edgar","filing":"0001567619-23-003363","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923003363/doc1.xml","form_type":"4"}},{"id":2049594,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2023-01-21T02:30:44.000Z","date":"2023-01-18","kind":"exercise","acquired":false,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The option was granted on April 1, 2013 and all shares subject to the option were fully vested and exercisable. The option will expire in approximately two months and be forfeited to the extent it is not exercised on or prior to March 31, 2023."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F6","text":"The Reporting Person holds options that give him the right to acquire an aggregate of 873,837 shares at exercise prices ranging from $6.73 to $32.45, of which 708,753 are currently exercisable, and 165,084 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to the Court Order."}],"balance_after":20000,"derivative":{"exercise_price":6.73,"expiration_date":"2023-03-31","underlying":"Ordinary Shares","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001567619-23-001097","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923001097/doc1.xml","form_type":"4"}},{"id":2049593,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-01-21T02:30:44.000Z","date":"2023-01-18","kind":"sale","acquired":false,"shares":638,"price":56.9709,"value":36347.4342,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The transaction was executed in multiple trades in prices ranging from $56.815 to $57.355, inclusive."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0001567619-23-001097","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923001097/doc1.xml","form_type":"4"}},{"id":2049592,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-01-21T02:30:44.000Z","date":"2023-01-18","kind":"sale","acquired":false,"shares":2085,"price":56.3242,"value":117435.957,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $55.78 to $56.755, inclusive."}],"balance_after":3838,"source":{"system":"sec-edgar","filing":"0001567619-23-001097","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923001097/doc1.xml","form_type":"4"}},{"id":2049591,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-01-21T02:30:44.000Z","date":"2023-01-18","kind":"sale","acquired":false,"shares":7277,"price":55.177,"value":401523.029,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $54.77 to $55.755, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in footnotes 2 through 4 of this Form 4."}],"balance_after":5923,"source":{"system":"sec-edgar","filing":"0001567619-23-001097","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923001097/doc1.xml","form_type":"4"}},{"id":2049590,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2023-01-21T02:30:44.000Z","date":"2023-01-18","kind":"exercise","acquired":true,"shares":10000,"price":6.73,"value":67300.0,"ownership":{"direct":true},"balance_after":13200,"source":{"system":"sec-edgar","filing":"0001567619-23-001097","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761923001097/doc1.xml","form_type":"4"}},{"id":2076706,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2022-12-24T02:30:31.000Z","date":"2022-12-21","kind":"exercise","acquired":false,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"The option was granted on April 1, 2013 and all shares subject to the option were fully vested and exercisable. The option will expire in approximately three months and be forfeited to the extent it is not exercised on or prior to March 31, 2023."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F5","text":"The Reporting Person holds options that give him the right to acquire an aggregate of 883,837 shares at exercise prices ranging from $6.73 to $32.45, of which 712,836 are currently exercisable, and 171,001 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to the Court Order."}],"balance_after":30000,"derivative":{"exercise_price":6.73,"expiration_date":"2023-03-31","underlying":"Ordinary Shares","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001567619-22-022010","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922022010/doc1.xml","form_type":"4"}},{"id":2076705,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-12-24T02:30:31.000Z","date":"2022-12-21","kind":"sale","acquired":false,"shares":6845,"price":59.2059,"value":405264.3855,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $58.87 to $59.86, inclusive."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0001567619-22-022010","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922022010/doc1.xml","form_type":"4"}},{"id":2076704,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-12-24T02:30:31.000Z","date":"2022-12-21","kind":"sale","acquired":false,"shares":3155,"price":58.4551,"value":184425.8405,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $57.855 to $58.84, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in footnotes 2 through 3 of this Form 4."}],"balance_after":10045,"source":{"system":"sec-edgar","filing":"0001567619-22-022010","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922022010/doc1.xml","form_type":"4"}},{"id":2076703,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-12-24T02:30:31.000Z","date":"2022-12-21","kind":"exercise","acquired":true,"shares":10000,"price":6.73,"value":67300.0,"ownership":{"direct":true},"balance_after":13200,"source":{"system":"sec-edgar","filing":"0001567619-22-022010","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922022010/doc1.xml","form_type":"4"}},{"id":2104171,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2022-11-26T02:31:49.000Z","date":"2022-11-23","kind":"exercise","acquired":false,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The option was granted on April 1, 2013 and all shares subject to the option were fully vested and exercisable. The option will expire in approximately four months and be forfeited to the extent it is not exercised on or prior to March 31, 2023."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F6","text":"The Reporting Person holds options that give him the right to acquire an aggregate of 893,837 shares at exercise prices ranging from $6.73 to $32.45, of which 720,857 are currently exercisable, and 172,980 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to the Court Order."}],"balance_after":40000,"derivative":{"exercise_price":6.73,"expiration_date":"2023-03-31","underlying":"Ordinary Shares","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001140361-22-043172","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036122043172/form4.xml","form_type":"4"}},{"id":2104170,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-11-26T02:31:49.000Z","date":"2022-11-23","kind":"sale","acquired":false,"shares":1469,"price":62.2788,"value":91487.5572,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The transaction was executed in multiple trades in prices ranging from $61.91 to $62.685, inclusive."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0001140361-22-043172","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036122043172/form4.xml","form_type":"4"}},{"id":2104169,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-11-26T02:31:49.000Z","date":"2022-11-23","kind":"sale","acquired":false,"shares":3984,"price":61.2764,"value":244125.1776,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $60.90 to $61.885, inclusive."}],"balance_after":4669,"source":{"system":"sec-edgar","filing":"0001140361-22-043172","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036122043172/form4.xml","form_type":"4"}},{"id":2104168,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-11-26T02:31:49.000Z","date":"2022-11-23","kind":"sale","acquired":false,"shares":4547,"price":60.5324,"value":275240.8228,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $59.885 to $60.88, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in footnotes 2 through 4 of this Form 4."}],"balance_after":8653,"source":{"system":"sec-edgar","filing":"0001140361-22-043172","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036122043172/form4.xml","form_type":"4"}},{"id":2104167,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-11-26T02:31:49.000Z","date":"2022-11-23","kind":"exercise","acquired":true,"shares":10000,"price":6.73,"value":67300.0,"ownership":{"direct":true},"balance_after":13200,"source":{"system":"sec-edgar","filing":"0001140361-22-043172","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036122043172/form4.xml","form_type":"4"}},{"id":2133498,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2022-10-22T01:30:20.000Z","date":"2022-10-19","kind":"exercise","acquired":false,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The option was granted on April 1, 2013 and all shares subject to the option were fully vested and exercisable. The option will expire in approximately five months and be forfeited to the extent it is not exercised on or prior to March 31, 2023."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F7","text":"The Reporting Person holds options that give him the right to acquire an aggregate of 903,837 shares at exercise prices ranging from $6.73 to $32.45, of which 721,003 are currently exercisable, and 182,834 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to the Court Order."}],"balance_after":50000,"derivative":{"exercise_price":6.73,"expiration_date":"2023-03-31","underlying":"Ordinary Shares","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001567619-22-018716","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922018716/doc1.xml","form_type":"4"}},{"id":2133497,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-10-22T01:30:20.000Z","date":"2022-10-19","kind":"sale","acquired":false,"shares":171,"price":58.1746,"value":9947.8566,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F5","text":"The transaction was executed in multiple trades in prices ranging from $58.05 to $58.20, inclusive."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0001567619-22-018716","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922018716/doc1.xml","form_type":"4"}},{"id":2133496,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-10-22T01:30:20.000Z","date":"2022-10-19","kind":"sale","acquired":false,"shares":4541,"price":57.3029,"value":260212.4689,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The transaction was executed in multiple trades in prices ranging from $56.84 to $57.72, inclusive."}],"balance_after":3371,"source":{"system":"sec-edgar","filing":"0001567619-22-018716","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922018716/doc1.xml","form_type":"4"}},{"id":2133495,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-10-22T01:30:20.000Z","date":"2022-10-19","kind":"sale","acquired":false,"shares":2520,"price":56.3037,"value":141885.324,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $55.805 to $56.77, inclusive."}],"balance_after":7912,"source":{"system":"sec-edgar","filing":"0001567619-22-018716","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922018716/doc1.xml","form_type":"4"}},{"id":2133494,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-10-22T01:30:20.000Z","date":"2022-10-19","kind":"sale","acquired":false,"shares":2768,"price":55.036,"value":152339.648,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $54.78 to $55.765, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in footnotes 2 through 5 of this Form 4."}],"balance_after":10432,"source":{"system":"sec-edgar","filing":"0001567619-22-018716","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922018716/doc1.xml","form_type":"4"}},{"id":2133493,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-10-22T01:30:20.000Z","date":"2022-10-19","kind":"exercise","acquired":true,"shares":10000,"price":6.73,"value":67300.0,"ownership":{"direct":true},"balance_after":13200,"source":{"system":"sec-edgar","filing":"0001567619-22-018716","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922018716/doc1.xml","form_type":"4"}},{"id":2151950,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2022-09-24T01:30:43.000Z","date":"2022-09-21","kind":"exercise","acquired":false,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The option was granted on April 1, 2013 and all shares subject to the option were fully vested and exercisable. The option will expire in approximately six months and be forfeited to the extent it is not exercised on or prior to March 31, 2023."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"The Reporting Person holds options that give him the right to acquire an aggregate of 913,837 shares at exercise prices ranging from $6.73 to $32.45, of which 725,087 are currently exercisable, and 188,750 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to the Court Order."}],"balance_after":60000,"derivative":{"exercise_price":6.73,"expiration_date":"2023-03-31","underlying":"Ordinary Shares","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001140361-22-034587","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036122034587/form4.xml","form_type":"4"}},{"id":2151949,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-09-24T01:30:43.000Z","date":"2022-09-21","kind":"sale","acquired":false,"shares":10000,"price":30.7496,"value":307496.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $30.47 to $30.875, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0001140361-22-034587","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036122034587/form4.xml","form_type":"4"}},{"id":2151948,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"officer":true,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-09-24T01:30:43.000Z","date":"2022-09-21","kind":"exercise","acquired":true,"shares":10000,"price":6.73,"value":67300.0,"ownership":{"direct":true},"balance_after":13200,"source":{"system":"sec-edgar","filing":"0001140361-22-034587","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036122034587/form4.xml","form_type":"4"}},{"id":2172810,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2022-08-27T01:31:08.000Z","date":"2022-08-24","kind":"exercise","acquired":false,"shares":10000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The option was granted on April 1, 2013 and all shares subject to the option were fully vested and exercisable. The option will expire in approximately seven months and be forfeited to the extent it is not exercised on or prior to March 31, 2023."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"The Reporting Person holds options that give him the right to acquire an aggregate of 923,837 shares at exercise prices ranging from $6.73 to $32.45, of which 733,107 are currently exercisable, and 190,730 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to the Court Order."}],"balance_after":70000,"derivative":{"exercise_price":6.73,"expiration_date":"2023-03-31","underlying":"Ordinary Shares","underlying_shares":10000},"source":{"system":"sec-edgar","filing":"0001567619-22-016737","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922016737/doc1.xml","form_type":"4"}},{"id":2172809,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-08-27T01:31:08.000Z","date":"2022-08-24","kind":"sale","acquired":false,"shares":10000,"price":30.1672,"value":301672.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $29.71 to $30.70, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0001567619-22-016737","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922016737/doc1.xml","form_type":"4"}},{"id":2172808,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-08-27T01:31:08.000Z","date":"2022-08-24","kind":"exercise","acquired":true,"shares":10000,"price":6.73,"value":67300.0,"ownership":{"direct":true},"balance_after":13200,"source":{"system":"sec-edgar","filing":"0001567619-22-016737","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922016737/doc1.xml","form_type":"4"}},{"id":2178319,"issuer":{"id":94695,"kind":"organization","name":"Rain Oncology Inc.","symbol":"RAIN"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (Right to Buy)","published_at":"2022-08-19T17:38:28.000Z","date":"2022-06-01","kind":"grant","acquired":true,"shares":20000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option represents a right to purchase a total of 20,000 shares of the Issuer's common stock, which will vest in full on June 1, 2023, subject to the Reporting Person's continued service to the Issuer."}],"balance_after":20000,"derivative":{"exercise_price":2.44,"expiration_date":"2032-06-01","underlying":"Common Stock","underlying_shares":20000},"source":{"system":"sec-edgar","filing":"0000899243-22-029317","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1724979/000089924322029317/doc4.xml","form_type":"4"}},{"id":2203234,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2022-07-23T01:37:07.000Z","date":"2022-07-22","kind":"exercise","acquired":false,"shares":7320,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The option was granted on April 1, 2013 and all shares subject to the option were fully vested and exercisable. The option will expire in approximately eight months and be forfeited to the extent it is not exercised on or prior to March 31, 2023."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F7","text":"The Reporting Person holds options that give him the right to acquire an aggregate of 933,837 shares at exercises prices ranging from $6.73 to $32.45, of which 733,253 are currently exercisable, and 200,584 are currently unexercisable but vest over time, subject to the Reporting Person's continued employment with the Issuer on each applicable vesting date of each option award. Certain of these options are subject to the Court Order."}],"balance_after":80000,"derivative":{"exercise_price":6.73,"expiration_date":"2023-03-31","underlying":"Ordinary Shares","underlying_shares":7320},"source":{"system":"sec-edgar","filing":"0001567619-22-014382","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":11,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922014382/doc1.xml","form_type":"4"}},{"id":2203233,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2022-07-23T01:37:07.000Z","date":"2022-07-21","kind":"exercise","acquired":false,"shares":20560,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The option was granted on April 1, 2013 and all shares subject to the option were fully vested and exercisable. The option will expire in approximately eight months and be forfeited to the extent it is not exercised on or prior to March 31, 2023."}],"balance_after":87320,"derivative":{"exercise_price":6.73,"expiration_date":"2023-03-31","underlying":"Ordinary Shares","underlying_shares":20560},"source":{"system":"sec-edgar","filing":"0001567619-22-014382","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":10,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922014382/doc1.xml","form_type":"4"}},{"id":2203232,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Stock Option (Right to Buy)","published_at":"2022-07-23T01:37:07.000Z","date":"2022-07-20","kind":"exercise","acquired":false,"shares":42120,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The option was granted on April 1, 2013 and all shares subject to the option were fully vested and exercisable. The option will expire in approximately eight months and be forfeited to the extent it is not exercised on or prior to March 31, 2023."}],"balance_after":107880,"derivative":{"exercise_price":6.73,"expiration_date":"2023-03-31","underlying":"Ordinary Shares","underlying_shares":42120},"source":{"system":"sec-edgar","filing":"0001567619-22-014382","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":9,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922014382/doc1.xml","form_type":"4"}},{"id":2203231,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-07-23T01:37:07.000Z","date":"2022-07-22","kind":"sale","acquired":false,"shares":7320,"price":32.5483,"value":238253.556,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F5","text":"The transaction was executed in multiple trades in prices ranging from $32.15 to $32.91, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0001567619-22-014382","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922014382/doc1.xml","form_type":"4"}},{"id":2203230,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-07-23T01:37:07.000Z","date":"2022-07-22","kind":"exercise","acquired":true,"shares":7320,"price":6.73,"value":49263.6,"ownership":{"direct":true},"balance_after":10520,"source":{"system":"sec-edgar","filing":"0001567619-22-014382","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922014382/doc1.xml","form_type":"4"}},{"id":2203229,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-07-23T01:37:07.000Z","date":"2022-07-21","kind":"sale","acquired":false,"shares":5,"price":33.69,"value":168.45,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0001567619-22-014382","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922014382/doc1.xml","form_type":"4"}},{"id":2203228,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-07-23T01:37:07.000Z","date":"2022-07-21","kind":"sale","acquired":false,"shares":20555,"price":32.6405,"value":670925.4775,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The transaction was executed in multiple trades in prices ranging from $32.28 to $32.895, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":3205,"source":{"system":"sec-edgar","filing":"0001567619-22-014382","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922014382/doc1.xml","form_type":"4"}},{"id":2203227,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-07-23T01:37:07.000Z","date":"2022-07-21","kind":"exercise","acquired":true,"shares":20560,"price":6.73,"value":138368.8,"ownership":{"direct":true},"balance_after":23760,"source":{"system":"sec-edgar","filing":"0001567619-22-014382","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922014382/doc1.xml","form_type":"4"}},{"id":2203226,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-07-23T01:37:07.000Z","date":"2022-07-20","kind":"sale","acquired":false,"shares":16984,"price":32.7321,"value":555921.9864,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The transaction was executed in multiple trades in prices ranging from $32.54 to $33.12, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0001567619-22-014382","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922014382/doc1.xml","form_type":"4"}},{"id":2203225,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2022-07-23T01:37:07.000Z","date":"2022-07-20","kind":"sale","acquired":false,"shares":25136,"price":32.3249,"value":812518.6864,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in the Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the Reporting Person in connection with a court stipulation and proposed order regarding the separation of assets (\"Court Order\") in anticipation of a potential divorce settlement agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The transaction was executed in multiple trades in prices ranging from $31.54 to $32.535, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The reporting person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."}],"balance_after":20184,"source":{"system":"sec-edgar","filing":"0001567619-22-014382","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761922014382/doc1.xml","form_type":"4"}},{"id":2203224,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Strategy Officer and CFO"}}],"security":"Ordinary Shares, par value $0.01 per 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Shares","underlying_shares":85000},"source":{"system":"sec-edgar","filing":"0001140361-22-006891","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000114036122006891/form4.xml","form_type":"4"}},{"id":2829558,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Stock Option (Right to Buy)","published_at":"2021-02-26T22:14:35.000Z","date":"2021-02-25","kind":"grant","acquired":true,"shares":84000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 25, 2022 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":84000,"derivative":{"exercise_price":22.6,"expiration_date":"2031-02-25","underlying":"Ordinary Shares","underlying_shares":84000},"source":{"system":"sec-edgar","filing":"0001567619-21-005091","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761921005091/doc1.xml","form_type":"4"}},{"id":2854337,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen 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In exchange, the reporting person received a replacement option, for 60,150 ordinary shares, having an exercise price of $22.85 per ordinary share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F8","text":"The shares subject to the option will vest and become exercisable as to 47/48 of the total number of shares subject to the option on the one year anniversary of the date of grant and with respect to 1/48 of the total number of shares subject to the option on February 21, 2022, subject to the reporting person's continued service with the issuer on each such vesting date."}],"balance_after":60150,"derivative":{"exercise_price":22.85,"expiration_date":"2028-02-21","underlying":"Ordinary Shares","underlying_shares":60150},"source":{"system":"sec-edgar","filing":"0001567619-21-004317","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761921004317/doc1.xml","form_type":"4"}},{"id":2854336,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2021-02-17T23:46:28.000Z","date":"2021-02-12","kind":"disposition_to_issuer","acquired":false,"shares":80000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F7","text":"On February 12, 2021, the issuer canceled, pursuant to the issuer's option exchange program, an option for 80,000 of the issuer's ordinary shares granted to the reporting person on February 21, 2018.  In exchange, the reporting person received a replacement option, for 60,150 ordinary shares, having an exercise price of $22.85 per ordinary share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 21, 2019 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the reporting person's continued employment with the issuer on each such vesting date."}],"balance_after":0,"derivative":{"exercise_price":33.1,"expiration_date":"2028-02-21","underlying":"Ordinary Shares","underlying_shares":80000},"source":{"system":"sec-edgar","filing":"0001567619-21-004317","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761921004317/doc1.xml","form_type":"4"}},{"id":2854335,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2021-02-17T23:46:28.000Z","date":"2021-02-12","kind":"grant","acquired":true,"shares":39062,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F5","text":"On February 12, 2021, the issuer canceled, pursuant to the issuer's option exchange program, an option for 75,000 of the issuer's ordinary shares granted to the reporting person on February 22, 2017.  In exchange, the reporting person received a replacement option, for 39,062 ordinary shares, having an exercise price of $22.85 per ordinary share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary."}],"balance_after":39062,"derivative":{"exercise_price":22.85,"expiration_date":"2027-02-22","underlying":"Ordinary Shares","underlying_shares":39062},"source":{"system":"sec-edgar","filing":"0001567619-21-004317","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761921004317/doc1.xml","form_type":"4"}},{"id":2854334,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2021-02-17T23:46:28.000Z","date":"2021-02-12","kind":"disposition_to_issuer","acquired":false,"shares":75000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F5","text":"On February 12, 2021, the issuer canceled, pursuant to the issuer's option exchange program, an option for 75,000 of the issuer's ordinary shares granted to the reporting person on February 22, 2017.  In exchange, the reporting person received a replacement option, for 39,062 ordinary shares, having an exercise price of $22.85 per ordinary share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 22, 2018 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the reporting person's continued employment with the issuer on each such vesting date."}],"balance_after":0,"derivative":{"exercise_price":55,"expiration_date":"2027-02-22","underlying":"Ordinary Shares","underlying_shares":75000},"source":{"system":"sec-edgar","filing":"0001567619-21-004317","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761921004317/doc1.xml","form_type":"4"}},{"id":2854333,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2021-02-17T23:46:28.000Z","date":"2021-02-12","kind":"grant","acquired":true,"shares":40625,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary."}],"balance_after":40625,"derivative":{"exercise_price":22.85,"expiration_date":"2026-02-24","underlying":"Ordinary Shares","underlying_shares":40625},"source":{"system":"sec-edgar","filing":"0001567619-21-004317","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761921004317/doc1.xml","form_type":"4"}},{"id":2854332,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2021-02-17T23:46:28.000Z","date":"2021-02-12","kind":"disposition_to_issuer","acquired":false,"shares":65000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"On February 12, 2021, the issuer canceled, pursuant to the issuer's option exchange program, an option for 65,000 of the issuer's ordinary shares granted to the reporting person on February 24, 2016.  In exchange, the reporting person received a replacement option, for 40,625 ordinary shares, having an exercise price of $22.85 per ordinary share."}],"balance_after":0,"derivative":{"exercise_price":34.61,"exercise_date":"2020-02-24","expiration_date":"2026-02-24","underlying":"Ordinary Shares","underlying_shares":65000},"source":{"system":"sec-edgar","filing":"0001567619-21-004317","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761921004317/doc1.xml","form_type":"4"}},{"id":2854331,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2021-02-17T23:46:28.000Z","date":"2021-02-12","kind":"grant","acquired":true,"shares":50000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On February 12, 2021, the issuer canceled, pursuant to the issuer's option exchange program, an option for 55,000 of the issuer's ordinary shares granted to the reporting person on March 11, 2015.  In exchange, the reporting person received a replacement option, for 50,000 ordinary shares, having an exercise price of $22.85 per ordinary share."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The shares subject to the option will vest and become exercisable on the one year anniversary of the date of grant, subject to the reporting person's continued service with the issuer through such one year anniversary."}],"balance_after":50000,"derivative":{"exercise_price":22.85,"expiration_date":"2025-03-11","underlying":"Ordinary Shares","underlying_shares":50000},"source":{"system":"sec-edgar","filing":"0001567619-21-004317","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761921004317/doc1.xml","form_type":"4"}},{"id":2854330,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Employee Stock Option (Right to Buy)","published_at":"2021-02-17T23:46:28.000Z","date":"2021-02-12","kind":"disposition_to_issuer","acquired":false,"shares":55000,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On February 12, 2021, the issuer canceled, pursuant to the issuer's option exchange program, an option for 55,000 of the issuer's ordinary shares granted to the reporting person on March 11, 2015.  In exchange, the reporting person received a replacement option, for 50,000 ordinary shares, having an exercise price of $22.85 per ordinary share."}],"balance_after":0,"derivative":{"exercise_price":27.81,"exercise_date":"2019-03-11","expiration_date":"2025-03-11","underlying":"Ordinary Shares","underlying_shares":55000},"source":{"system":"sec-edgar","filing":"0001567619-21-004317","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000156761921004317/doc1.xml","form_type":"4"}},{"id":3243799,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Stock Option (Right to 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2019, with 100% of the total shares vested and exercisable on June 11, 2020, subject to the reporting person's provision of service to the issuer on each vesting date."}],"balance_after":30000,"derivative":{"exercise_price":0.66,"expiration_date":"2029-06-11","underlying":"Common Stock","underlying_shares":30000},"source":{"system":"sec-edgar","filing":"0001209191-19-036487","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000120919119036487/doc4.xml","form_type":"4"}},{"id":3623137,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Stock Option (right to 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become exercisable as to 25% of the total number of shares subject to the option on June 21, 2019 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":250000,"derivative":{"exercise_price":15.04,"expiration_date":"2028-06-21","underlying":"Ordinary Shares","underlying_shares":250000},"source":{"system":"sec-edgar","filing":"0000899243-18-017937","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000089924318017937/doc4.xml","form_type":"4"}},{"id":3893812,"issuer":{"id":125698,"kind":"organization","name":"Sierra Oncology, Inc.","symbol":"SRRA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen 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vest and become exercisable as to 25% of the total number of shares subject to the option on February 21, 2019 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":80000,"derivative":{"exercise_price":33.1,"expiration_date":"2028-02-21","underlying":"Ordinary Shares","underlying_shares":80000},"source":{"system":"sec-edgar","filing":"0000899243-18-005298","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000089924318005298/doc4.xml","form_type":"4"}},{"id":4282212,"issuer":{"id":125698,"kind":"organization","name":"Sierra Oncology, Inc.","symbol":"SRRA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen 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purchased in multiple trades at prices ranging from $51.2492 to $51.46 inclusive.  The price reported in Column 4 above reflects the weighted average purchase price.  The Reporting Person hereby undertakes to provide upon request to the SEC staff, the Issuer, or a stockholder of the Issuer, information regarding the number of shares and prices at which the transaction was effected."}],"balance_after":3200,"source":{"system":"sec-edgar","filing":"0000899243-17-006986","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000089924317006986/doc4.xml","form_type":"4"}},{"id":4424543,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":27743,"kind":"person","name":"Nguyen Tran","position":1,"cik":"0001457013","reported_name":"Nguyen Tran","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Financial Officer"}}],"security":"Stock Option (right to buy)","published_at":"2017-02-24T21:05:27.000Z","date":"2017-02-22","kind":"grant","acquired":true,"shares":75000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The shares subject to the option will vest and become exercisable as to 25% of the total number of shares subject to the option on February 22, 2018 and with respect to 1/48th of the total number of shares subject to the option in successive, equal monthly installments on each monthly anniversary thereafter, subject to the Reporting Person's continued employment with the Issuer on each such vesting date."}],"balance_after":75000,"derivative":{"exercise_price":55,"expiration_date":"2027-02-22","underlying":"Ordinary Shares","underlying_shares":75000},"source":{"system":"sec-edgar","filing":"0000899243-17-005217","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1457013/000089924317005217/doc4.xml","form_type":"4"}}]}