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These shares were purchased in multiple transactions at prices ranging from $8.2100 to $8.6000, inclusive. The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnotes (1) and (2) to this Form 4."}],"balance_after":439000,"source":{"system":"sec-edgar","filing":"0001045463-26-000020","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1559053/000104546326000020/primary_doc.xml","form_type":"4"}},{"id":4635861,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-10-06T17:53:53.000Z","date":"2026-10-02","kind":"purchase","planned":false,"acquired":true,"shares":100000,"price":8.5724,"value":857240.0,"ownership":{"direct":false,"nature":"By Spouse"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.5150 to $8.6098, inclusive. The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of ProthenaCorp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4."}],"balance_after":314000,"source":{"system":"sec-edgar","filing":"0001045463-26-000019","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1559053/000104546326000019/primary_doc.xml","form_type":"4"}},{"id":4633757,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-09-30T21:10:27.000Z","date":"2026-09-29","kind":"purchase","planned":false,"acquired":true,"shares":162000,"price":8.677,"value":1405674.0,"ownership":{"direct":false,"nature":"By Spouse"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.6000 to $8.7550, inclusive. The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4."}],"balance_after":214000,"source":{"system":"sec-edgar","filing":"0001045463-26-000018","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1045463/000104546326000018/primary_doc.xml","form_type":"4"}},{"id":4633792,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-09-29T21:37:37.000Z","date":"2026-09-28","kind":"purchase","planned":false,"acquired":true,"shares":103500,"price":8.5978,"value":889872.3,"ownership":{"direct":false,"nature":"By Manatee Equity Fund LLC"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.1582 to $8.8500, inclusive. The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein."}],"balance_after":187000,"source":{"system":"sec-edgar","filing":"0001045463-26-000017","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1045463/000104546326000017/primary_doc.xml","form_type":"4"}},{"id":4623268,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-09-21T20:23:38.000Z","date":"2026-09-18","kind":"purchase","planned":false,"acquired":true,"shares":100000,"price":8.4346,"value":843460.0,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.3350 to $8.4829, inclusive. The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4."}],"balance_after":927000,"source":{"system":"sec-edgar","filing":"0001045463-26-000016","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1559053/000104546326000016/primary_doc.xml","form_type":"4"}},{"id":3426,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-09-03T22:23:53.000Z","date":"2026-09-02","kind":"purchase","planned":false,"acquired":true,"shares":27000,"price":9.4718,"value":255738.6,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $9.4072 to $9.6100, inclusive. The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4."}],"balance_after":827000,"source":{"system":"sec-edgar","filing":"0001045463-26-000015","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1559053/000104546326000015/primary_doc.xml","form_type":"4"}},{"id":679206,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-08-21T18:32:10.000Z","date":"2026-08-20","kind":"purchase","planned":false,"acquired":true,"shares":50000,"price":8.7886,"value":439430.0,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.7497 to $8.9000, inclusive. The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4."}],"balance_after":800000,"source":{"system":"sec-edgar","filing":"0001045463-26-000014","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1045463/000104546326000014/primary_doc.xml","form_type":"4"}},{"id":684181,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-08-18T20:03:25.000Z","date":"2026-08-18","kind":"gift","planned":false,"acquired":false,"shares":627553,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":750000,"source":{"system":"sec-edgar","filing":"0001045463-26-000013","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1045463/000104546326000013/primary_doc.xml","form_type":"4"}},{"id":684180,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-08-18T20:03:25.000Z","date":"2026-08-17","kind":"gift","planned":false,"acquired":true,"shares":336000,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":1377553,"source":{"system":"sec-edgar","filing":"0001045463-26-000013","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1045463/000104546326000013/primary_doc.xml","form_type":"4"}},{"id":691199,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-08-11T20:08:06.000Z","date":"2026-08-10","kind":"gift","planned":false,"acquired":true,"shares":251553,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":1041553,"source":{"system":"sec-edgar","filing":"0001045463-26-000011","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1045463/000104546326000011/primary_doc.xml","form_type":"4"}},{"id":692210,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-08-10T19:24:31.000Z","date":"2026-08-07","kind":"purchase","planned":false,"acquired":true,"shares":3500,"price":8.6192,"value":30167.2,"ownership":{"direct":false,"nature":"By Manatee Equity Fund LLC"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. 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The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reporting person disclaims beneficial ownership of these securities except to the extent of his pecuniary interest therein."}],"balance_after":83500,"source":{"system":"sec-edgar","filing":"0001045463-26-000010","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1045463/000104546326000010/primary_doc.xml","form_type":"4"}},{"id":692209,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-08-10T19:24:31.000Z","date":"2026-08-07","kind":"purchase","planned":false,"acquired":true,"shares":34000,"price":8.6192,"value":293052.8,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. 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The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4."}],"balance_after":790000,"source":{"system":"sec-edgar","filing":"0001045463-26-000010","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1045463/000104546326000010/primary_doc.xml","form_type":"4"}},{"id":732569,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-06-18T15:38:32.000Z","date":"2026-06-16","kind":"purchase","planned":false,"acquired":true,"shares":20000,"price":7.8995,"value":157990.0,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $7.8600 to $7.9312, inclusive. The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4."}],"balance_after":756000,"source":{"system":"sec-edgar","filing":"0001045463-26-000009","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1045463/000104546326000009/primary_doc.xml","form_type":"4"}},{"id":736655,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-06-16T20:58:55.000Z","date":"2026-06-15","kind":"gift","planned":false,"acquired":false,"shares":325000,"price":0,"value":0.0,"ownership":{"direct":true},"balance_after":736000,"source":{"system":"sec-edgar","filing":"0001045463-26-000008","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1045463/000104546326000008/primary_doc.xml","form_type":"4"}},{"id":740443,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-06-12T21:59:45.000Z","date":"2026-06-11","kind":"purchase","planned":false,"acquired":true,"shares":125000,"price":8.1698,"value":1021225.0,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $7.8400 to $8.4300, inclusive. The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4."}],"balance_after":1061000,"source":{"system":"sec-edgar","filing":"0001045463-26-000007","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1045463/000104546326000007/primary_doc.xml","form_type":"4"}},{"id":748530,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-06-05T17:46:44.000Z","date":"2026-06-04","kind":"purchase","planned":false,"acquired":true,"shares":50000,"price":9.3059,"value":465295.0,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $9.1000 to $9.4097, inclusive. The reporting person undertakes to provide to Prothena Corp Public Ltd Co, any security holder of Prothena Corp Public Ltd Co, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth in footnote (1) to this Form 4."}],"balance_after":936000,"source":{"system":"sec-edgar","filing":"0001045463-26-000006","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1045463/000104546326000006/primary_doc.xml","form_type":"4"}},{"id":752681,"issuer":{"id":2375,"kind":"organization","name":"PROTHENA CORP PUBLIC LTD CO","symbol":"PRTA"},"owners":[{"id":2376,"kind":"person","name":"SCULLY WILLIAM P","position":1,"cik":"0001045463","reported_name":"SCULLY WILLIAM P","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Ordinary Shares, par value $0.01 per share","published_at":"2026-06-03T16:41:54.000Z","date":"2026-06-02","kind":"purchase","planned":false,"acquired":true,"shares":50000,"price":9.426,"value":471300.0,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $9.2323 to $9.4892, inclusive. 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