{"transactions":[{"id":682715,"issuer":{"id":3693,"kind":"organization","name":"RHYTHM PHARMACEUTICALS, INC.","symbol":"RYTM"},"owners":[{"id":22033,"kind":"person","name":"Joshi Manher","position":1,"cik":"0001978048","reported_name":"Joshi Manher","relationship":{"officer":true,"officer_title":"Chief Medical Officer"}}],"security":"Restricted Stock Units","published_at":"2026-08-18T21:35:38.000Z","date":"2026-08-17","kind":"grant","planned":false,"acquired":true,"shares":25000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The Restricted Stock Units vest as to 25% of the Restricted Stock Units on September 1 of each of 2027, 2028, 2029, and 2030, such that the Restricted Stock Units shall be fully vested on September 1, 2030, subject to the Reporting Person continuing in service through each such vesting date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"The restricted stock units have no expiration date."}],"balance_after":25000,"derivative":{"exercise_price":0,"underlying":"Common Stock","underlying_shares":25000},"source":{"system":"sec-edgar","filing":"0001649904-26-000020","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1649904/000164990426000020/form4.xml","form_type":"4"}},{"id":682714,"issuer":{"id":3693,"kind":"organization","name":"RHYTHM PHARMACEUTICALS, INC.","symbol":"RYTM"},"owners":[{"id":22033,"kind":"person","name":"Joshi Manher","position":1,"cik":"0001978048","reported_name":"Joshi Manher","relationship":{"officer":true,"officer_title":"Chief Medical Officer"}}],"security":"Stock Options (Right to Buy)","published_at":"2026-08-18T21:35:38.000Z","date":"2026-08-17","kind":"grant","planned":false,"acquired":true,"shares":50000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The Stock Options vest and become exercisable as to 25% of the total number of shares subject to the option on the first anniversary of the grant date and as to 6.25% of the total number of shares subject to the option upon the Reporting Person's completion of each successive three months of service to the Corporation."}],"balance_after":50000,"derivative":{"exercise_price":115.44,"expiration_date":"2036-08-16","underlying":"Common Stock","underlying_shares":50000},"source":{"system":"sec-edgar","filing":"0001649904-26-000020","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1649904/000164990426000020/form4.xml","form_type":"4"}},{"id":774936,"issuer":{"id":46432,"kind":"organization","name":"SOLENO THERAPEUTICS INC","symbol":"SLNO"},"owners":[{"id":22033,"kind":"person","name":"Joshi Manher","position":1,"cik":"0001978048","reported_name":"Joshi Manher","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Development Officer"}}],"security":"Stock Option (Right to buy)","published_at":"2026-05-18T20:39:52.000Z","date":"2026-05-18","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":4700,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"At the effective time of the Merger, this option was cancelled in exchange for a cash payment equal to (x) the difference between the Merger Consideration and the per share exercise price of the option, multiplied by (y) the number of shares covered by the option as of immediately prior to such cancellation."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"At the effective time of the Merger, this option was cancelled in exchange for a cash payment equal to (x) the difference between the Merger Consideration and the per share exercise price of the option, multiplied by (y) the number of shares covered by the option as of immediately prior to such cancellation."}],"balance_after":0,"derivative":{"exercise_price":43.65,"expiration_date":"2036-01-21","underlying":"Common Stock","underlying_shares":4700},"source":{"system":"sec-edgar","filing":"0001978048-26-000002","document":"form4-05182026_080547.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1484565/000197804826000002/form4-05182026_080547.xml","form_type":"4"}},{"id":774935,"issuer":{"id":46432,"kind":"organization","name":"SOLENO THERAPEUTICS INC","symbol":"SLNO"},"owners":[{"id":22033,"kind":"person","name":"Joshi Manher","position":1,"cik":"0001978048","reported_name":"Joshi Manher","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Development Officer"}}],"security":"Stock Option (Right to buy)","published_at":"2026-05-18T20:39:52.000Z","date":"2026-05-18","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":72321,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"At the effective time of the Merger, this option was cancelled in exchange for a cash payment equal to (x) the difference between the Merger Consideration and the per share exercise price of the option, multiplied by (y) the number of shares covered by the option as of immediately prior to such cancellation."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"At the effective time of the Merger, this option was cancelled in exchange for a cash payment equal to (x) the difference between the Merger Consideration and the per share exercise price of the option, multiplied by (y) the number of shares covered by the option as of immediately prior to such cancellation."}],"balance_after":0,"derivative":{"exercise_price":46.31,"expiration_date":"2035-11-10","underlying":"Common Stock","underlying_shares":72321},"source":{"system":"sec-edgar","filing":"0001978048-26-000002","document":"form4-05182026_080547.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1484565/000197804826000002/form4-05182026_080547.xml","form_type":"4"}},{"id":774934,"issuer":{"id":46432,"kind":"organization","name":"SOLENO THERAPEUTICS INC","symbol":"SLNO"},"owners":[{"id":22033,"kind":"person","name":"Joshi Manher","position":1,"cik":"0001978048","reported_name":"Joshi Manher","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Development Officer"}}],"security":"Common Stock","published_at":"2026-05-18T20:39:52.000Z","date":"2026-05-18","kind":"disposition_to_issuer","planned":false,"acquired":false,"shares":20171,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"These shares are represented by previously reported restricted stock units (\"RSUs\"). Pursuant to the Agreement and Plan of Merger, dated as of April 5, 2026, by and among Soleno Therapeutics, Inc. (the \"Company\"), Neocrine Biosciences, Inc. (\"Parent\") and Sigma Merger Sub, Inc. (\"Merger Sub\"), on May 18, 2026, Merger Sub merged with and into the Company (the \"Merger\"), with the Company continuing as the surviving corporation and a wholly owned subsidiary of Parent. In connection with the Merger, each issued and outstanding vested and unvested RSU was cancelled and converted into the right to receive an amount equal to $53.00 in cash (the \"Merger Consideration\")."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"In connection with the Merger, each issued and outstanding share of the Company's Common Stock was cancelled and converted into the right to receive an amount in cash equal to the Merger Consideration."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001978048-26-000002","document":"form4-05182026_080547.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1484565/000197804826000002/form4-05182026_080547.xml","form_type":"4"}},{"id":932246,"issuer":{"id":46432,"kind":"organization","name":"SOLENO THERAPEUTICS INC","symbol":"SLNO"},"owners":[{"id":22033,"kind":"person","name":"Joshi Manher","position":1,"cik":"0001978048","reported_name":"Joshi Manher","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Development Officer"}}],"security":"Employee stock option (right to buy)","published_at":"2026-01-23T23:04:03.000Z","date":"2026-01-21","kind":"grant","planned":false,"acquired":true,"shares":4700,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"1/48th of the shares subject to the option shall vest on February 1, 2026 and each one-month anniversary thereafter, subject to the Reporting Person continuing to be a Service Provider (as defined in the Issuer's 2014 Equity Incentive Plan) through each such date."}],"balance_after":4700,"derivative":{"exercise_price":43.65,"expiration_date":"2036-01-21","underlying":"Common Stock","underlying_shares":4700},"source":{"system":"sec-edgar","filing":"0001978048-26-000001","document":"form4-01232026_110157.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1484565/000197804826000001/form4-01232026_110157.xml","form_type":"4"}},{"id":932245,"issuer":{"id":46432,"kind":"organization","name":"SOLENO THERAPEUTICS INC","symbol":"SLNO"},"owners":[{"id":22033,"kind":"person","name":"Joshi Manher","position":1,"cik":"0001978048","reported_name":"Joshi Manher","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Development Officer"}}],"security":"Common Stock","published_at":"2026-01-23T23:04:03.000Z","date":"2026-01-21","kind":"grant","planned":false,"acquired":true,"shares":4100,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"These securities are restricted stock units (\"RSUs\"). Each RSU represents a contingent right to receive one share of Common Stock. 100% of the RSUs shall vest on December 15, 2027, subject to the Reporting Person continuing to be a Service Provider (as defined in the Issuer's 2014 Equity Incentive Plan) through such date."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"These securities are RSUs. Each RSU represents a contingent right to receive one share of Common Stock, subject to the applicable vesting schedule and conditions of each RSU."}],"balance_after":20171,"source":{"system":"sec-edgar","filing":"0001978048-26-000001","document":"form4-01232026_110157.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1484565/000197804826000001/form4-01232026_110157.xml","form_type":"4"}},{"id":1001953,"issuer":{"id":46432,"kind":"organization","name":"SOLENO THERAPEUTICS INC","symbol":"SLNO"},"owners":[{"id":22033,"kind":"person","name":"Joshi Manher","position":1,"cik":"0001978048","reported_name":"Joshi Manher","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Development Officer"}}],"security":"Employee stock option (right to buy)","published_at":"2025-11-12T22:21:09.000Z","date":"2025-11-10","kind":"exercise","planned":false,"acquired":true,"shares":72321,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"One-fourth of the shares subject to the option shall vest on November 10, 2026 and one forty-eighth of the shares subject to the option shall vest each month thereafter on the same day of the month, subject to the Reporting Person continuing to be a Service Provider (as defined in the Issuer's 2014 Equity Incentive Plan) through each such date."}],"balance_after":72321,"derivative":{"exercise_price":46.31,"expiration_date":"2035-11-10","underlying":"Common Stock","underlying_shares":72321},"source":{"system":"sec-edgar","filing":"0001978048-25-000003","document":"form4-11122025_101105.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1484565/000197804825000003/form4-11122025_101105.xml","form_type":"4"}},{"id":1001952,"issuer":{"id":46432,"kind":"organization","name":"SOLENO THERAPEUTICS INC","symbol":"SLNO"},"owners":[{"id":22033,"kind":"person","name":"Joshi Manher","position":1,"cik":"0001978048","reported_name":"Joshi Manher","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Development Officer"}}],"security":"Common Stock","published_at":"2025-11-12T22:21:09.000Z","date":"2025-11-10","kind":"grant","planned":false,"acquired":true,"shares":16071,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"These securities are restricted stock units (\"RSUs\"). Each RSU represents a contingent right to receive one share of Common Stock. One-half of the RSUs shall vest on November 10, 2026 and one third of the remaining RSUs shall vest each one-year anniversary thereafter, subject to the Reporting Person continuing to be a Service Provider (as defined in the Issuer's 2014 Equity Incentive Plan) through each such date."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"These securities are restricted stock units (\"RSUs\"). Each RSU represents a contingent right to receive one share of Common Stock. One-half of the RSUs shall vest on November 10, 2026 and one third of the remaining RSUs shall vest each one-year anniversary thereafter, subject to the Reporting Person continuing to be a Service Provider (as defined in the Issuer's 2014 Equity Incentive Plan) through each such date."}],"balance_after":16071,"source":{"system":"sec-edgar","filing":"0001978048-25-000003","document":"form4-11122025_101105.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1484565/000197804825000003/form4-11122025_101105.xml","form_type":"4"}},{"id":1734200,"issuer":{"id":6828,"kind":"organization","name":"Atara Biotherapeutics, Inc.","symbol":"ATRA"},"owners":[{"id":22033,"kind":"person","name":"Joshi Manher","position":1,"cik":"0001978048","reported_name":"Joshi Manher","relationship":{"officer":true,"officer_title":"EVP, Chief Medical Officer"}}],"security":"Common Stock","published_at":"2023-11-20T22:30:19.000Z","date":"2023-11-16","kind":"sale","planned":false,"acquired":false,"shares":12287,"price":0.389,"value":4779.643,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Shares sold automatically to satisfy tax withholding obligations in connection with the vesting of previously granted restricted stock units, pursuant to a sale-to-cover provision in the award agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The sale price of the reporting person's shares represents the weighted average price of all shares sold by a broker on November 16, 2023 on behalf of a group of employees of the Issuer to satisfy the payment of withholding tax liability of such employee."}],"balance_after":171284,"source":{"system":"sec-edgar","filing":"0000905148-23-001510","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1604464/000090514823001510/form4.xml","form_type":"4"}},{"id":1801575,"issuer":{"id":6828,"kind":"organization","name":"Atara Biotherapeutics, Inc.","symbol":"ATRA"},"owners":[{"id":22033,"kind":"person","name":"Joshi Manher","position":1,"cik":"0001978048","reported_name":"Joshi Manher","relationship":{"officer":true,"officer_title":"EVP, Chief Medical Officer"}}],"security":"Common Stock","published_at":"2023-08-18T22:25:09.000Z","date":"2023-08-16","kind":"sale","planned":false,"acquired":false,"shares":3773,"price":1.653,"value":6236.769,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Shares sold automatically to satisfy tax withholding obligations in connection with the vesting of previously granted restricted stock units, pursuant to a sale-to-cover provision in the award agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The sale price of the reporting person's shares represents the weighted average price of all shares sold by a broker on August 16, 2023 and August 17, 2023 on behalf of a group of employees of the Issuer to satisfy the payment of withholding tax liability of such employee."}],"balance_after":183571,"source":{"system":"sec-edgar","filing":"0001140361-23-040560","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1604464/000114036123040560/form4.xml","form_type":"4"}},{"id":1801574,"issuer":{"id":6828,"kind":"organization","name":"Atara Biotherapeutics, Inc.","symbol":"ATRA"},"owners":[{"id":22033,"kind":"person","name":"Joshi Manher","position":1,"cik":"0001978048","reported_name":"Joshi Manher","relationship":{"officer":true,"officer_title":"EVP, Chief Medical Officer"}}],"security":"Common Stock","published_at":"2023-08-18T22:25:09.000Z","date":"2023-08-16","kind":"sale","planned":false,"acquired":false,"shares":3202,"price":1.652,"value":5289.704,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Shares sold automatically to satisfy tax withholding obligations in connection with the vesting of previously granted restricted stock units, pursuant to a sale-to-cover provision in the award agreement."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The sale price of the reporting person's shares represents the weighted average price of all shares sold by a broker on August 16, 2023 and August 17, 2023 on behalf of a group of employees of the Issuer to satisfy the payment of withholding tax liability of such employee."}],"balance_after":187344,"source":{"system":"sec-edgar","filing":"0001140361-23-040560","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1604464/000114036123040560/form4.xml","form_type":"4"}}]}