{"transactions":[{"id":4255656,"issuer":{"id":8383,"kind":"organization","name":"Capstone Holding Corp."},"owners":[{"id":30208,"kind":"organization","name":"BVF PARTNERS L P/IL","position":1,"cik":"0001055947","reported_name":"BVF PARTNERS L P/IL","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":30209,"kind":"organization","name":"BIOTECHNOLOGY VALUE FUND L P","position":2,"cik":"0000918923","reported_name":"BIOTECHNOLOGY VALUE FUND L P","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":30211,"kind":"organization","name":"BIOTECHNOLOGY VALUE FUND II LP","position":3,"cik":"0001102444","reported_name":"BIOTECHNOLOGY VALUE FUND II LP","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":174373,"kind":"organization","name":"BVF INVESTMENTS LLC","position":4,"cik":"0001132245","reported_name":"BVF INVESTMENTS LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":30216,"kind":"organization","name":"BVF INC/IL","position":5,"cik":"0001056807","reported_name":"BVF INC/IL","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":30217,"kind":"person","name":"LAMPERT MARK N","position":6,"cik":"0001233840","reported_name":"LAMPERT MARK N","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}}],"security":"Common Stock, $0.0005 par value","published_at":"2017-07-18T23:59:00.000Z","date":"2017-07-14","kind":"sale","acquired":false,"shares":105713,"price":0.06,"value":6342.78,"ownership":{"direct":false,"nature":"By Biotechnology Value Fund II, L.P."},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"This Form 4 is filed jointly by Biotechnology Value Fund, L.P. (\"BVF\"), Biotechnology Value Fund II, L.P. (\"BVF2\"), BVF Investments, L.L.C. (\"BVFLLC\"), BVF Partners L.P. (\"Partners\"), BVF Inc., and Mark Lampert (collectively the \"Reporting Persons\"). Each of the Reporting Persons is a member of a Section 13G group that no longer owns more than 10% of the Issuer's outstanding shares of Common Stock pursuant to Rule 16a-1(a)(1). Each of the Reporting Persons disclaims beneficial ownership of the shares of Common Stock reported herein except to the extent of his or its pecuniary interest therein."},{"field":"kind","element":"transactionCoding","label":"F6","text":"On the Transaction Date, the Reporting Persons entered into and consummated a private sale with an entity that is unaffiliated with the Reporting Persons."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F5","text":"Shares of Common Stock owned directly by BVF2. As the general partner of BVF2, Partners may be deemed to beneficially own the shares of Common Stock owned directly by BVF2. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the shares of Common Stock owned directly by BVF2. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the shares of Common Stock owned directly by BVF2."}],"balance_after":890487,"source":{"system":"sec-edgar","filing":"0000921895-17-001936","document":"form407422010_07182017.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/887151/000092189517001936/form407422010_07182017.xml","form_type":"4"}},{"id":4255655,"issuer":{"id":8383,"kind":"organization","name":"Capstone Holding Corp."},"owners":[{"id":30208,"kind":"organization","name":"BVF PARTNERS L P/IL","position":1,"cik":"0001055947","reported_name":"BVF PARTNERS L P/IL","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":30209,"kind":"organization","name":"BIOTECHNOLOGY VALUE FUND L P","position":2,"cik":"0000918923","reported_name":"BIOTECHNOLOGY VALUE FUND L P","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":30211,"kind":"organization","name":"BIOTECHNOLOGY VALUE FUND II LP","position":3,"cik":"0001102444","reported_name":"BIOTECHNOLOGY VALUE FUND II LP","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":174373,"kind":"organization","name":"BVF INVESTMENTS LLC","position":4,"cik":"0001132245","reported_name":"BVF INVESTMENTS LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":30216,"kind":"organization","name":"BVF INC/IL","position":5,"cik":"0001056807","reported_name":"BVF INC/IL","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":30217,"kind":"person","name":"LAMPERT MARK N","position":6,"cik":"0001233840","reported_name":"LAMPERT MARK N","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}}],"security":"Common Stock, $0.0005 par value","published_at":"2017-07-18T23:59:00.000Z","date":"2017-07-14","kind":"sale","acquired":false,"shares":242236,"price":0.06,"value":14534.16,"ownership":{"direct":false,"nature":"By Biotechnology Value Fund, L.P."},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"This Form 4 is filed jointly by Biotechnology Value Fund, L.P. (\"BVF\"), Biotechnology Value Fund II, L.P. (\"BVF2\"), BVF Investments, L.L.C. (\"BVFLLC\"), BVF Partners L.P. (\"Partners\"), BVF Inc., and Mark Lampert (collectively the \"Reporting Persons\"). Each of the Reporting Persons is a member of a Section 13G group that no longer owns more than 10% of the Issuer's outstanding shares of Common Stock pursuant to Rule 16a-1(a)(1). Each of the Reporting Persons disclaims beneficial ownership of the shares of Common Stock reported herein except to the extent of his or its pecuniary interest therein."},{"field":"kind","element":"transactionCoding","label":"F6","text":"On the Transaction Date, the Reporting Persons entered into and consummated a private sale with an entity that is unaffiliated with the Reporting Persons."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F4","text":"Shares of Common Stock owned directly by BVF. As the general partner of BVF, Partners may be deemed to beneficially own the shares of Common Stock owned directly by BVF. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the shares of Common Stock owned directly by BVF. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the shares of Common Stock owned directly by BVF."}],"balance_after":1377652,"source":{"system":"sec-edgar","filing":"0000921895-17-001936","document":"form407422010_07182017.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/887151/000092189517001936/form407422010_07182017.xml","form_type":"4"}},{"id":4255654,"issuer":{"id":8383,"kind":"organization","name":"Capstone Holding Corp."},"owners":[{"id":30208,"kind":"organization","name":"BVF PARTNERS L P/IL","position":1,"cik":"0001055947","reported_name":"BVF PARTNERS L P/IL","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":30209,"kind":"organization","name":"BIOTECHNOLOGY VALUE FUND L P","position":2,"cik":"0000918923","reported_name":"BIOTECHNOLOGY VALUE FUND L P","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":30211,"kind":"organization","name":"BIOTECHNOLOGY VALUE FUND II LP","position":3,"cik":"0001102444","reported_name":"BIOTECHNOLOGY VALUE FUND II LP","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":174373,"kind":"organization","name":"BVF INVESTMENTS LLC","position":4,"cik":"0001132245","reported_name":"BVF INVESTMENTS LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":30216,"kind":"organization","name":"BVF INC/IL","position":5,"cik":"0001056807","reported_name":"BVF INC/IL","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}},{"id":30217,"kind":"person","name":"LAMPERT MARK N","position":6,"cik":"0001233840","reported_name":"LAMPERT MARK N","relationship":{"director":false,"officer":false,"ten_percent_owner":false,"other":true,"other_text":"See Explanation of Responses"}}],"security":"Common Stock, $0.0005 par value","published_at":"2017-07-18T23:59:00.000Z","date":"2017-07-14","kind":"sale","acquired":false,"shares":3993637,"price":0.06,"value":239618.22,"ownership":{"direct":false,"nature":"By BVF Investments, L.L.C."},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"This Form 4 is filed jointly by Biotechnology Value Fund, L.P. (\"BVF\"), Biotechnology Value Fund II, L.P. (\"BVF2\"), BVF Investments, L.L.C. (\"BVFLLC\"), BVF Partners L.P. (\"Partners\"), BVF Inc., and Mark Lampert (collectively the \"Reporting Persons\"). Each of the Reporting Persons is a member of a Section 13G group that no longer owns more than 10% of the Issuer's outstanding shares of Common Stock pursuant to Rule 16a-1(a)(1). Each of the Reporting Persons disclaims beneficial ownership of the shares of Common Stock reported herein except to the extent of his or its pecuniary interest therein."},{"field":"kind","element":"transactionCoding","label":"F6","text":"On the Transaction Date, the Reporting Persons entered into and consummated a private sale with an entity that is unaffiliated with the Reporting Persons."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"Shares of Common Stock owned directly by BVFLLC. As the manager of BVFLLC, Partners may be deemed to beneficially own the shares of Common Stock owned directly by BVFLLC. As the investment adviser and general partner of Partners, BVF Inc. may be deemed to beneficially own the shares of Common Stock owned directly by BVFLLC. As a director and officer of BVF Inc., Mr. Lampert may be deemed to beneficially own the shares of Common Stock owned directly by BVFLLC."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Pursuant to the operating agreement of BVFLLC, Partners is authorized, among other things, to invest the contributed capital of Samana Capital, L.P., the majority member of BVFLLC, in the Common Stock and other securities of the Issuer and to vote, exercise or convert and dispose of such securities and is entitled to receive fees based on assets under management and, subject to certain exceptions, allocations based on realized and unrealized gains on such assets."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0000921895-17-001936","document":"form407422010_07182017.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/887151/000092189517001936/form407422010_07182017.xml","form_type":"4"}}]}