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The securities directly held by HVA V are indirectly held by the individual managing members of HVA V (each, a \"Managing Member\" and collectively, the \"Managing Members\"). The Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his or her pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Following the reported transaction, 3,067,962 shares of the reportable securities are owned directly by Hatteras Venture Partners IV SBIC, LP (\"HVP IV\"). Hatteras Venture Advisors IV SBIC, LLC (\"HVA IV SBIC\") is the general partner of HVP IV. The securities directly held by HVP IV are indirectly held by the individual managing members of HVA IV SBIC (each, a \"GP Managing Member\" and collectively, the \"GP Managing Members\"). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Following the reported transaction, in which none of the reportable securities owned directly by Hatteras NC Fund, LP (\"Hatteras NC\") were sold, 210,464 shares of the reportable securities are owned directly by Hatteras NC. Hatteras Venture Advisors IV, LLC (\"HVA IV\") is the general partner of Hatteras NC. The securities directly held by Hatteras NC are indirectly held by the individual managing members of HVA IV (each, a \"HVA IV Managing Member\"). The HVA IV Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The HVA IV Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each HVA IV Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any HVA IV Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his or her pecuniary interest therein."}],"balance_after":3279421,"source":{"system":"sec-edgar","filing":"0001209191-18-034839","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919118034839/doc4.xml","form_type":"4"}},{"id":3920693,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":4,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":5,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-05-23T20:46:07.000Z","date":"2018-05-23","kind":"sale","acquired":false,"shares":26,"price":50.5,"value":1313.0,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"995 shares of the reportable securities are owned directly by Hatteras Venture Advisors V, LLC (\"HVA V\"). The securities directly held by HVA V are indirectly held by the individual managing members of HVA V (each, a \"Managing Member\" and collectively, the \"Managing Members\"). The Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his or her pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F12","text":"Following the reported transaction, 3,826,252 shares of the reportable securities are owned directly by HVP IV."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F13","text":"Following the reported transaction, 210,464 shares of the reportable securities are owned directly by Hatteras NC."}],"balance_after":4037711,"source":{"system":"sec-edgar","filing":"0001209191-18-032789","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919118032789/doc4.xml","form_type":"4"}},{"id":3920692,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":4,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":5,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-05-23T20:46:07.000Z","date":"2018-05-23","kind":"sale","acquired":false,"shares":474,"price":50.5,"value":23937.0,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"995 shares of the reportable securities are owned directly by Hatteras Venture Advisors V, LLC (\"HVA V\"). The securities directly held by HVA V are indirectly held by the individual managing members of HVA V (each, a \"Managing Member\" and collectively, the \"Managing Members\"). The Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his or her pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F11","text":"Following the reported transaction, 210,490 shares of the reportable securities are owned directly by Hatteras NC."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F12","text":"Following the reported transaction, 3,826,252 shares of the reportable securities are owned directly by HVP IV."}],"balance_after":4037737,"source":{"system":"sec-edgar","filing":"0001209191-18-032789","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919118032789/doc4.xml","form_type":"4"}},{"id":3920691,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":4,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":5,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-05-23T20:46:07.000Z","date":"2018-05-22","kind":"sale","acquired":false,"shares":308,"price":50.6851,"value":15611.0108,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F9","text":"The price represents the weighted average price with a low of $50.50 and a high of $51.25."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"995 shares of the reportable securities are owned directly by Hatteras Venture Advisors V, LLC (\"HVA V\"). The securities directly held by HVA V are indirectly held by the individual managing members of HVA V (each, a \"Managing Member\" and collectively, the \"Managing Members\"). The Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his or her pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F10","text":"Following the reported transaction, 3,826,726 shares of the reportable securities are owned directly by HVP IV."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F11","text":"Following the reported transaction, 210,490 shares of the reportable securities are owned directly by Hatteras NC."}],"balance_after":4038211,"source":{"system":"sec-edgar","filing":"0001209191-18-032789","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919118032789/doc4.xml","form_type":"4"}},{"id":3920690,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":4,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":5,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-05-23T20:46:07.000Z","date":"2018-05-22","kind":"sale","acquired":false,"shares":5592,"price":50.8593,"value":284405.2056,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F9","text":"The price represents the weighted average price with a low of $50.50 and a high of $51.25."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"995 shares of the reportable securities are owned directly by Hatteras Venture Advisors V, LLC (\"HVA V\"). The securities directly held by HVA V are indirectly held by the individual managing members of HVA V (each, a \"Managing Member\" and collectively, the \"Managing Members\"). The Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his or her pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F8","text":"Following the reported transaction, 210,798 shares of the reportable securities are owned directly by Hatteras NC."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F10","text":"Following the reported transaction, 3,826,726 shares of the reportable securities are owned directly by HVP IV."}],"balance_after":4038519,"source":{"system":"sec-edgar","filing":"0001209191-18-032789","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919118032789/doc4.xml","form_type":"4"}},{"id":3920689,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":4,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":5,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-05-23T20:46:07.000Z","date":"2018-05-21","kind":"sale","acquired":false,"shares":26,"price":52.13,"value":1355.38,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F6","text":"The price represents the weighted average price with a low of $52.12 and a high of $52.14."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"995 shares of the reportable securities are owned directly by Hatteras Venture Advisors V, LLC (\"HVA V\"). The securities directly held by HVA V are indirectly held by the individual managing members of HVA V (each, a \"Managing Member\" and collectively, the \"Managing Members\"). The Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his or her pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F7","text":"Following the reported transaction, 3,832,318 shares of the reportable securities are owned directly by HVP IV."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F8","text":"Following the reported transaction, 210,798 shares of the reportable securities are owned directly by Hatteras NC."}],"balance_after":4044111,"source":{"system":"sec-edgar","filing":"0001209191-18-032789","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919118032789/doc4.xml","form_type":"4"}},{"id":3920688,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":4,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":5,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-05-23T20:46:07.000Z","date":"2018-05-21","kind":"sale","acquired":false,"shares":474,"price":52.13,"value":24709.62,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F6","text":"The price represents the weighted average price with a low of $52.12 and a high of $52.14."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"995 shares of the reportable securities are owned directly by Hatteras Venture Advisors V, LLC (\"HVA V\"). The securities directly held by HVA V are indirectly held by the individual managing members of HVA V (each, a \"Managing Member\" and collectively, the \"Managing Members\"). The Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his or her pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Following the reported transaction, 210,824 shares of the reportable securities are owned directly by Hatteras NC."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F7","text":"Following the reported transaction, 3,832,318 shares of the reportable securities are owned directly by HVP IV."}],"balance_after":4044137,"source":{"system":"sec-edgar","filing":"0001209191-18-032789","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919118032789/doc4.xml","form_type":"4"}},{"id":3920687,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":4,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":5,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-05-23T20:46:07.000Z","date":"2018-05-21","kind":"sale","acquired":false,"shares":1595,"price":51.0589,"value":81438.9455,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price represents the weighted average price with a low of $51.00 and a high of $51.755. The Reporting Persons undertake to provide G1 Therapeutics, Inc., any security holder of G1 Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in footnote 1 to this Form 4."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Following the reported transaction, 3,832,792 shares of the reportable securities are owned directly by Hatteras Venture Partners IV SBIC, LP (\"HVP IV\"). Hatteras Venture Advisors IV SBIC, LLC (\"HVA IV SBIC\") is the general partner of HVP IV. The securities directly held by HVP IV are indirectly held by the individual managing members of HVA IV SBIC (each, a \"GP Managing Member\" and collectively, the \"GP Managing Members\"). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"995 shares of the reportable securities are owned directly by Hatteras Venture Advisors V, LLC (\"HVA V\"). The securities directly held by HVA V are indirectly held by the individual managing members of HVA V (each, a \"Managing Member\" and collectively, the \"Managing Members\"). The Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his or her pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Following the reported transaction, 210,824 shares of the reportable securities are owned directly by Hatteras NC."}],"balance_after":4044611,"source":{"system":"sec-edgar","filing":"0001209191-18-032789","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919118032789/doc4.xml","form_type":"4"}},{"id":3920686,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":4,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":5,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-05-23T20:46:07.000Z","date":"2018-05-21","kind":"sale","acquired":false,"shares":29005,"price":51.1604,"value":1483907.402,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price represents the weighted average price with a low of $51.00 and a high of $51.755. The Reporting Persons undertake to provide G1 Therapeutics, Inc., any security holder of G1 Therapeutics, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in footnote 1 to this Form 4."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Following the reported transaction, 3,832,792 shares of the reportable securities are owned directly by Hatteras Venture Partners IV SBIC, LP (\"HVP IV\"). Hatteras Venture Advisors IV SBIC, LLC (\"HVA IV SBIC\") is the general partner of HVP IV. The securities directly held by HVP IV are indirectly held by the individual managing members of HVA IV SBIC (each, a \"GP Managing Member\" and collectively, the \"GP Managing Members\"). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Following the reported transaction, 212,419 shares of the reportable securities are owned directly by Hatteras NC Fund, LP (\"Hatteras NC\"). Hatteras Venture Advisors IV, LLC (\"HVA IV\") is the general partner of Hatteras NC Fund, LP. The securities directly held by Hatteras NC are indirectly held by the individual managing members of HVA IV (each, a \"HVA IV Managing Member\" and collectively, the \"HVA IV Managing Members\"). The HVA IV Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The HVA IV Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each HVA IV Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any HVA IV Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"995 shares of the reportable securities are owned directly by Hatteras Venture Advisors V, LLC (\"HVA V\"). The securities directly held by HVA V are indirectly held by the individual managing members of HVA V (each, a \"Managing Member\" and collectively, the \"Managing Members\"). The Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his or her pecuniary interest therein."}],"balance_after":4046206,"source":{"system":"sec-edgar","filing":"0001209191-18-032789","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919118032789/doc4.xml","form_type":"4"}},{"id":4144414,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":4,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":5,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-12-04T17:01:19.000Z","date":"2017-11-30","kind":"other","acquired":true,"shares":995,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F5","text":"In-kind distribution from L2 Ventures, LLC to its members, including Hatteras Venture Advisors V, LLC, without consideration."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"3,861,797 shares of the reportable securities are owned directly by Hatteras Venture Partners IV SBIC, LP (\"HVP IV\"). Hatteras Venture Advisors IV SBIC, LLC (\"HVA IV SBIC\") is the general partner of HVP IV. The securities directly held by HVP IV are indirectly held by the individual managing members of HVA IV SBIC (each, a \"GP Managing Member\" and collectively, the \"GP Managing Members\"). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"212,419 shares of the reportable securities are owned directly by Hatteras NC Fund, LP (\"Hatteras NC\"). Hatteras Venture Advisors IV, LLC (\"HVA IV\") is the general partner of Hatteras NC Fund, LP. The securities directly held by Hatteras NC are indirectly held by the individual managing members of HVA IV (each, a \"HVA IV Managing Member\" and collectively, the \"HVA IV Managing Members\"). The HVA IV Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The HVA IV Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each HVA IV Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any HVA IV Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"995 shares of the reportable securities are owned directly by Hatteras Venture Advisors V, LLC (\"HVA V\"). The securities directly held by HVA V are indirectly held by the individual managing members of HVA V (each, a \"Managing Member\" and collectively, the \"Managing Members\"). The Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his or her pecuniary interest therein."}],"balance_after":4075211,"source":{"system":"sec-edgar","filing":"0001209191-17-063608","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919117063608/doc4.xml","form_type":"4"}},{"id":4144413,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":4,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":5,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-12-04T17:01:19.000Z","date":"2017-11-30","kind":"other","acquired":false,"shares":99513,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"In-kind distribution from L2 Ventures, LLC to its members, without consideration."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"3,861,797 shares of the reportable securities are owned directly by Hatteras Venture Partners IV SBIC, LP (\"HVP IV\"). Hatteras Venture Advisors IV SBIC, LLC (\"HVA IV SBIC\") is the general partner of HVP IV. The securities directly held by HVP IV are indirectly held by the individual managing members of HVA IV SBIC (each, a \"GP Managing Member\" and collectively, the \"GP Managing Members\"). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"212,419 shares of the reportable securities are owned directly by Hatteras NC Fund, LP (\"Hatteras NC\"). Hatteras Venture Advisors IV, LLC (\"HVA IV\") is the general partner of Hatteras NC Fund, LP. The securities directly held by Hatteras NC are indirectly held by the individual managing members of HVA IV (each, a \"HVA IV Managing Member\" and collectively, the \"HVA IV Managing Members\"). The HVA IV Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The HVA IV Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each HVA IV Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any HVA IV Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Following a distribution in-kind to its members, none of the reportable securities are owned directly by L2 Ventures, LLC (\"L2 Ventures\"). Hatteras Venture Advisors V, LLC (\"HVA V\") is the general partner of L2 Ventures. The securities previously held by L2 Ventures were indirectly held by the individual managing members of HVA V (each, a \"L2 Managing Member\" and collectively, the \"L2 Managing Members\"). The L2 Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram."}],"balance_after":4074216,"source":{"system":"sec-edgar","filing":"0001209191-17-063608","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919117063608/doc4.xml","form_type":"4"}},{"id":4306583,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":4,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":5,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series C Preferred Stock","published_at":"2017-05-24T20:18:49.000Z","date":"2017-05-22","kind":"exercise","acquired":false,"shares":1009693,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted to Common Stock on a 1-for-3 basis."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted to Common Stock on a 1-for-3 basis."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into shares of Common Stock upon consummation of the Issuer's initial public offering and had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F6","text":"The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into shares of Common Stock upon consummation of the Issuer's initial public offering and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reportable securities are owned directly by Hatteras Venture Partners IV SBIC, LP (\"HVP IV\"). Hatteras Venture Advisors IV SBIC, LLC (\"HVA IV SBIC\") is the general partner of HVP IV. The securities directly held by HVP IV are indirectly held by the individual managing members of HVA IV SBIC (each, a \"GP Managing Member\" and collectively, the \"GP Managing Members\"). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The reportable securities are owned directly by L2 Ventures, LLC (\"L2 Ventures\"). Hatteras Venture Advisors V, LLC (\"HVA V\") is the general partner of L2 Ventures. The securities directly held by L2 Ventures are indirectly held by the individual managing members of HVA V (each, a \"L2 Managing Member\" and collectively, the \"L2 Managing Members\"). The L2 Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The L2 Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each L2 Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any L2 Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F9","text":"Includes shares of Series C Preferred Stock convertible into 294,493 shares of the Issuer's common stock held by HVP IV and shares of Series C Preferred Stock convertible into 42,070 shares of the Issuer's common stock held by L2 Ventures, LLC."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":336563},"source":{"system":"sec-edgar","filing":"0001209191-17-035173","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919117035173/doc4.xml","form_type":"4"}},{"id":4306582,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":4,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":5,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series B Preferred Stock","published_at":"2017-05-24T20:18:49.000Z","date":"2017-05-22","kind":"exercise","acquired":false,"shares":2584959,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted to Common Stock on a 1-for-3 basis."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted to Common Stock on a 1-for-3 basis."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into shares of Common Stock upon consummation of the Issuer's initial public offering and had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F6","text":"The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into shares of Common Stock upon consummation of the Issuer's initial public offering and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reportable securities are owned directly by Hatteras Venture Partners IV SBIC, LP (\"HVP IV\"). Hatteras Venture Advisors IV SBIC, LLC (\"HVA IV SBIC\") is the general partner of HVP IV. The securities directly held by HVP IV are indirectly held by the individual managing members of HVA IV SBIC (each, a \"GP Managing Member\" and collectively, the \"GP Managing Members\"). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The reportable securities are owned directly by L2 Ventures, LLC (\"L2 Ventures\"). Hatteras Venture Advisors V, LLC (\"HVA V\") is the general partner of L2 Ventures. The securities directly held by L2 Ventures are indirectly held by the individual managing members of HVA V (each, a \"L2 Managing Member\" and collectively, the \"L2 Managing Members\"). The L2 Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The L2 Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each L2 Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any L2 Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F8","text":"Includes shares of Series B Preferred Stock convertible into 804,208 shares of the Issuer's common stock held by HVP IV and shares of Series B Preferred Stock convertible into 57,443 shares of the Issuer's common stock held by L2 Ventures, LLC."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":861651},"source":{"system":"sec-edgar","filing":"0001209191-17-035173","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919117035173/doc4.xml","form_type":"4"}},{"id":4306581,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":4,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":5,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A Preferred Stock","published_at":"2017-05-24T20:18:49.000Z","date":"2017-05-22","kind":"exercise","acquired":false,"shares":6568527,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted to Common Stock on a 1-for-3 basis."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted to Common Stock on a 1-for-3 basis."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into shares of Common Stock upon consummation of the Issuer's initial public offering and had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F6","text":"The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into shares of Common Stock upon consummation of the Issuer's initial public offering and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reportable securities are owned directly by Hatteras Venture Partners IV SBIC, LP (\"HVP IV\"). Hatteras Venture Advisors IV SBIC, LLC (\"HVA IV SBIC\") is the general partner of HVP IV. The securities directly held by HVP IV are indirectly held by the individual managing members of HVA IV SBIC (each, a \"GP Managing Member\" and collectively, the \"GP Managing Members\"). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The reportable securities are owned directly by Hatteras NC Fund, LP (\"Hatteras NC\"). Hatteras Venture Advisors IV, LLC (\"HVA IV\") is the general partner of Hatteras NC Fund, LP. The securities directly held by Hatteras NC are indirectly held by the individual managing members of HVA IV (each, a \"HVA IV Managing Member\" and collectively, the \"HVA IV Managing Members\"). The HVA IV Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The HVA IV Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each HVA IV Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any HVA IV Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F7","text":"Includes shares of Series A Preferred Stock convertible into 1,990,276 shares of the Issuer's common stock held by HVP IV and shares of Series A Preferred Stock convertible into 199,232 shares of the Issuer's common stock held by Hatteras NC."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":2189508},"source":{"system":"sec-edgar","filing":"0001209191-17-035173","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919117035173/doc4.xml","form_type":"4"}},{"id":4306580,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":4,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":5,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series 1 Preferred Stock","published_at":"2017-05-24T20:18:49.000Z","date":"2017-05-22","kind":"exercise","acquired":false,"shares":1318681,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted to Common Stock on a 1-for-3 basis."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted to Common Stock on a 1-for-3 basis."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into shares of Common Stock upon consummation of the Issuer's initial public offering and had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F6","text":"The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock automatically converted into shares of Common Stock upon consummation of the Issuer's initial public offering and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reportable securities are owned directly by Hatteras Venture Partners IV SBIC, LP (\"HVP IV\"). Hatteras Venture Advisors IV SBIC, LLC (\"HVA IV SBIC\") is the general partner of HVP IV. The securities directly held by HVP IV are indirectly held by the individual managing members of HVA IV SBIC (each, a \"GP Managing Member\" and collectively, the \"GP Managing Members\"). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":439560},"source":{"system":"sec-edgar","filing":"0001209191-17-035173","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919117035173/doc4.xml","form_type":"4"}},{"id":4306579,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":4,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":5,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-05-24T20:18:49.000Z","date":"2017-05-22","kind":"purchase","acquired":true,"shares":133333,"price":15,"value":1999995.0,"ownership":{"direct":false,"nature":"By Hatteras Venture Partners IV SBIC, LP"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F5","text":"Reflects shares Hatteras Venture Partners IV SBIC, LP purchased in the initial public offering at the initial public offering price of $15.00 per share."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reportable securities are owned directly by Hatteras Venture Partners IV SBIC, LP (\"HVP IV\"). Hatteras Venture Advisors IV SBIC, LLC (\"HVA IV SBIC\") is the general partner of HVP IV. The securities directly held by HVP IV are indirectly held by the individual managing members of HVA IV SBIC (each, a \"GP Managing Member\" and collectively, the \"GP Managing Members\"). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."}],"balance_after":3861797,"source":{"system":"sec-edgar","filing":"0001209191-17-035173","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919117035173/doc4.xml","form_type":"4"}},{"id":4306578,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":4,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":5,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-05-24T20:18:49.000Z","date":"2017-05-22","kind":"exercise","acquired":true,"shares":99513,"ownership":{"direct":false,"nature":"By L2 Ventures, LLC"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted to Common Stock on a 1-for-3 basis."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The reportable securities are owned directly by L2 Ventures, LLC (\"L2 Ventures\"). Hatteras Venture Advisors V, LLC (\"HVA V\") is the general partner of L2 Ventures. The securities directly held by L2 Ventures are indirectly held by the individual managing members of HVA V (each, a \"L2 Managing Member\" and collectively, the \"L2 Managing Members\"). The L2 Managing Members are John Crumpler, Clay Thorp, Christy Shaffer, Douglas Reed and Robert Ingram. The L2 Managing Members may share voting and dispositive power over the securities directly held by HVA V. Each L2 Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any L2 Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."}],"balance_after":99513,"source":{"system":"sec-edgar","filing":"0001209191-17-035173","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919117035173/doc4.xml","form_type":"4"}},{"id":4306577,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":4,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":5,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-05-24T20:18:49.000Z","date":"2017-05-22","kind":"exercise","acquired":true,"shares":212419,"ownership":{"direct":false,"nature":"By Hatteras NC Fund, LP"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted to Common Stock on a 1-for-3 basis."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The reportable securities are owned directly by Hatteras NC Fund, LP (\"Hatteras NC\"). Hatteras Venture Advisors IV, LLC (\"HVA IV\") is the general partner of Hatteras NC Fund, LP. The securities directly held by Hatteras NC are indirectly held by the individual managing members of HVA IV (each, a \"HVA IV Managing Member\" and collectively, the \"HVA IV Managing Members\"). The HVA IV Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The HVA IV Managing Members may share voting and dispositive power over the securities directly held by HVP IV. Each HVA IV Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any HVA IV Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."}],"balance_after":212419,"source":{"system":"sec-edgar","filing":"0001209191-17-035173","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000120919117035173/doc4.xml","form_type":"4"}},{"id":4306576,"issuer":{"id":87413,"kind":"organization","name":"G1 Therapeutics, Inc.","symbol":"GTHX"},"owners":[{"id":82876,"kind":"person","name":"Thorp Clay","position":1,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166141,"kind":"organization","name":"Hatteras Venture Advisors IV SBIC, LLC","position":2,"cik":"0001675236","reported_name":"Hatteras Venture Advisors IV SBIC, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":166142,"kind":"organization","name":"Hatteras Venture Partners IV SBIC, LP","position":3,"cik":"0001675232","reported_name":"Hatteras Venture Partners IV SBIC, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162814,"kind":"person","name":"Crumpler John","position":4,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":5,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-05-24T20:18:49.000Z","date":"2017-05-22","kind":"exercise","acquired":true,"shares":3728464,"ownership":{"direct":false,"nature":"By Hatteras Venture Partners IV SBIC, LP"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The Preferred Stock automatically converted into Common Stock upon the closing of the Issuer's initial public offering pursuant to the Issuer's Fifth Restated Certificate of Incorporation, as amended, based on the conversion rate in effect at the time of conversion. The Series 1 Preferred Stock, Series A Preferred Stock, Series B Preferred Stock and Series C Preferred Stock converted to Common Stock on a 1-for-3 basis."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reportable securities are owned directly by Hatteras Venture Partners IV SBIC, LP (\"HVP IV\"). Hatteras Venture Advisors IV SBIC, LLC (\"HVA IV SBIC\") is the general partner of HVP IV. The securities directly held by HVP IV are indirectly held by the individual managing members of HVA IV SBIC (each, a \"GP Managing Member\" and collectively, the \"GP Managing Members\"). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP IV. 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Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."}],"balance_after":1764197,"source":{"system":"sec-edgar","filing":"0001578563-17-000002","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000157856317000002/primary_doc.xml","form_type":"4"}},{"id":4486679,"issuer":{"id":82875,"kind":"organization","name":"Clearside Biomedical, Inc.","symbol":"CLSD"},"owners":[{"id":162807,"kind":"organization","name":"Hatteras Venture Advisors III, LLC","position":1,"cik":"0001674177","reported_name":"Hatteras Venture Advisors III, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":true,"other_text":"May be part of a 13(d) Group"}},{"id":162808,"kind":"organization","name":"Hatteras Ventures Partners III LP","position":2,"cik":"0001390733","reported_name":"Hatteras Ventures Partners III LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":true,"other_text":"May be part of a 13(d) Group"}},{"id":162809,"kind":"organization","name":"Hatteras Venture Affiliates III Lp","position":3,"cik":"0001390738","reported_name":"Hatteras Venture Affiliates III Lp","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":true,"other_text":"May be part of a 13(d) Group"}},{"id":162814,"kind":"person","name":"Crumpler John","position":4,"cik":"0001674107","reported_name":"Crumpler John","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":true,"other_text":"May be part of a 13(d) Group"}},{"id":16884,"kind":"person","name":"INGRAM ROBERT ALEXANDER","position":5,"cik":"0001219890","reported_name":"INGRAM ROBERT ALEXANDER","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":true,"other_text":"May be part of a 13(d) Group"}},{"id":112297,"kind":"person","name":"LEE KENNETH B JR","position":6,"cik":"0001208570","reported_name":"LEE KENNETH B JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":true,"other_text":"May be part of a 13(d) Group"}},{"id":162813,"kind":"person","name":"Reed Douglas MD","position":7,"cik":"0001291262","reported_name":"Reed Douglas MD","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":true,"other_text":"May be part of a 13(d) Group"}},{"id":82876,"kind":"person","name":"Thorp Clay","position":8,"cik":"0001592380","reported_name":"Thorp Clay","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":true,"other_text":"May be part of a 13(d) Group"}}],"security":"Common Stock","published_at":"2017-01-19T17:53:47.000Z","date":"2017-01-17","kind":"sale","acquired":false,"shares":8366,"price":8.92,"value":74624.72,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"This transaction was executed in multiple trades at prices ranging from $8.68 to $9.22. The price reported in Column 4 is a weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder of the Issuer full information regarding the number of shares and prices at which the transactions were effected."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reportable securities are owned directly by Hatteras Venture Partners III, LP (\"HVP\") and Hatteras Venture Affiliates III, LP (\"HVA\"). Hatteras Venture Advisors III, LLC is the general partner of HVP and HVA (the \"GP\"). The shares directly held by HVP and HVA are indirectly held by the individual managing members of GP (each, a \"GP Managing Member\" and collectively, the \"GP Managing Members\"). The GP Managing Members are John Crumpler, Clay Thorp, Ken Lee, Douglas Reed and Robert Ingram. The GP Managing Members may share voting and dispositive power over the securities directly held by HVP and HVA. Each GP Managing Member disclaims beneficial ownership of these securities and this report is not an admission that any GP Managing Member is a beneficial owner of such securities for purposes of Section 16 or for any other purpose, except to the extent of his pecuniary interest therein."}],"balance_after":1774654,"source":{"system":"sec-edgar","filing":"0001578563-17-000002","document":"primary_doc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1674107/000157856317000002/primary_doc.xml","form_type":"4"}}]}