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The preferred stock automatically convert into common stock upon the closing of the Issuer's initial public offering held on July 20, 2018."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Shares held by Flagship Ventures Fund IV-Rx, L.P. (\"Flagship Fund IV-Rx\"). Flagship Fund IV GP is the general partner of Flagship IV-Rx. Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship Fund IV GP. Flagship Fund IV GP and each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship IV-Rx. Each of the filing persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein."}],"balance_after":3830402,"source":{"system":"sec-edgar","filing":"0001104659-18-046534","document":"a4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1724939/000110465918046534/a4.xml","form_type":"4"}},{"id":3862936,"issuer":{"id":116417,"kind":"organization","name":"Rubius Therapeutics, Inc.","symbol":"RUBY"},"owners":[{"id":97142,"kind":"organization","name":"Flagship Ventures Fund IV General Partner LLC","position":1,"cik":"0001508051","reported_name":"Flagship Ventures Fund IV General Partner LLC","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157564,"kind":"organization","name":"Flagship VentureLabs IV, LLC","position":2,"cik":"0001642578","reported_name":"Flagship VentureLabs IV, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":111426,"kind":"organization","name":"Flagship Ventures Fund IV, L.P.","position":3,"cik":"0001503559","reported_name":"Flagship Ventures Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":126697,"kind":"organization","name":"Flagship Ventures Fund IV-Rx, L.P.","position":4,"cik":"0001590973","reported_name":"Flagship Ventures Fund IV-Rx, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69364,"kind":"person","name":"Flagship Ventures Fund V, L.P.","position":5,"cik":"0001627639","reported_name":"Flagship Ventures Fund V, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":109677,"kind":"organization","name":"Flagship V VentureLabs Rx Fund, L.P.","position":6,"cik":"0001724939","reported_name":"Flagship V VentureLabs Rx Fund, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":69366,"kind":"person","name":"Flagship Ventures Opportunities Fund I, L.P.","position":7,"cik":"0001677345","reported_name":"Flagship Ventures Opportunities Fund I, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":44731,"kind":"person","name":"Afeyan Noubar","position":8,"cik":"0001222012","reported_name":"AFEYAN NOUBAR","relationship":{"director":true,"officer":false,"ten_percent_owner":true,"other":false}},{"id":44658,"kind":"person","name":"Kania Edwin","position":9,"cik":"0001255927","reported_name":"KANIA EDWIN M JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-07-23T16:34:53.000Z","date":"2018-07-20","kind":"exercise","acquired":true,"shares":15323593,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The preferred stock is convertible into the Issuer's common stock on a one-for-one basis at the holder's election and has no expiration date. The preferred stock automatically convert into common stock upon the closing of the Issuer's initial public offering held on July 20, 2018."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Shares held by Flagship Fund IV. Flagship Fund IV GP is the general partner of Flagship Fund IV. Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship Fund IV GP and each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship Fund IV. Each of the filing persons disclaims beneficial ownership of such shares except to the extent of his or its pecuniary interest therein."}],"balance_after":15323593,"source":{"system":"sec-edgar","filing":"0001104659-18-046534","document":"a4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1724939/000110465918046534/a4.xml","form_type":"4"}},{"id":3933117,"issuer":{"id":108468,"kind":"organization","name":"Evelo Biosciences, Inc.","symbol":"EVLO"},"owners":[{"id":97142,"kind":"organization","name":"Flagship Ventures Fund IV General Partner LLC","position":1,"cik":"0001508051","reported_name":"Flagship Ventures Fund IV General Partner LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157564,"kind":"organization","name":"Flagship VentureLabs IV, LLC","position":2,"cik":"0001642578","reported_name":"Flagship VentureLabs IV, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":111426,"kind":"organization","name":"Flagship Ventures Fund IV, L.P.","position":3,"cik":"0001503559","reported_name":"Flagship Ventures Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":126697,"kind":"organization","name":"Flagship Ventures Fund IV-Rx, L.P.","position":4,"cik":"0001590973","reported_name":"Flagship Ventures Fund IV-Rx, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series C Preferred Stock","published_at":"2018-05-15T20:43:24.000Z","date":"2018-05-11","kind":"exercise","acquired":false,"shares":4643963,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Following the transactions reported herein, Flagship VentureLabs IV LLC (\"VentureLabs IV\") holds 684,372 shares of common stock, Flagship VentureLabs V LLC (\"VentureLabs V\") holds 2,645,637 shares of common stock, Flagship Ventures Fund IV L.P. (\"Flagship Fund IV\") holds 1,836,836 shares of common stock, Flagship Ventures Fund IV-Rx, L.P. (\"Flagship Fund IV-Rx\" and, together with VentureLabs IV and Flagship Fund IV, the \"Flagship Fund IV Funds\") holds 448,911 shares of common stock,  Flagship Ventures Fund V, L.P. (\"Flagship Fund V\") holds 4,201,284 shares of common stock, Flagship V VentureLabs Rx Fund, L.P. (\"VentureLabs Rx V\") holds 1,609,871  shares of common stock,  Nutritional Health Side Fund, L.P. (\"Nutritional Health Side Fund\") holds 795,950 shares of common stock,"},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"[Continued] Nutritional Health Disruptive Innovation Fund, L.P. (\"Nutritional Innovation Fund\" and, together with VentureLabs V, Flagship Fund V, VentureLabs Rx V and Nutritional Health Side Fund, the \"Flagship Fund V Funds\") holds 3,598,177 shares of common stock, and Flagship Ventures Opportunities Fund I, L.P. (\"Flagship Opportunities I\" and, together with the Flagship Fund IV Funds and Flagship Fund V Funds, the \"Flagship Funds\") holds 2,412,365 shares of common stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Flagship Fund IV is a member of VentureLabs IV and also serves as its manager. Flagship Fund V is a member of VentureLabs V and also serves as its manager."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The general partner of each of Flagship Fund IV and Flagship Fund IV-Rx is Flagship Ventures Fund IV General Partner LLC (\"Flagship Fund IV GP\"). The general partner of Flagship Fund V, VentureLabs Rx-V, Nutritional Innovation Fund and Nutritional Health Side Fund is Flagship Ventures Fund V General Partner LLC (\"Flagship Fund V GP\"). The general partner of Flagship Opportunities Fund I is Flagship Ventures Opportunities Fund I General Partner LLC (\"Flagship Opportunities GP,\" and together with Flagship Fund IV GP and Flagship Fund V GP, the \"Flagship General Partners\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship Fund IV GP and each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship Fund IV Funds. Dr. Afeyan also serves as the managing member of the Flagship Fund V GP and Flagship Opportunities Fund GP and may be deemed to possess sole voting and investment control over the shares held by the Flagship Fund V Funds and Flagship Opportunities Fund I. Each of the Flagship General Partners, Dr. Afeyan and Mr. Kania  disclaims beneficial ownership of any shares beneficially owned by the Flagship Funds except to the extent of its or his pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":1138505},"source":{"system":"sec-edgar","filing":"0000899243-18-013014","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1694665/000089924318013014/doc4.xml","form_type":"4"}},{"id":3933116,"issuer":{"id":108468,"kind":"organization","name":"Evelo Biosciences, Inc.","symbol":"EVLO"},"owners":[{"id":97142,"kind":"organization","name":"Flagship Ventures Fund IV General Partner LLC","position":1,"cik":"0001508051","reported_name":"Flagship Ventures Fund IV General Partner LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157564,"kind":"organization","name":"Flagship VentureLabs IV, LLC","position":2,"cik":"0001642578","reported_name":"Flagship VentureLabs IV, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":111426,"kind":"organization","name":"Flagship Ventures Fund IV, L.P.","position":3,"cik":"0001503559","reported_name":"Flagship Ventures Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":126697,"kind":"organization","name":"Flagship Ventures Fund IV-Rx, L.P.","position":4,"cik":"0001590973","reported_name":"Flagship Ventures Fund IV-Rx, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series B Preferred Stock","published_at":"2018-05-15T20:43:24.000Z","date":"2018-05-11","kind":"exercise","acquired":false,"shares":18611110,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Following the transactions reported herein, Flagship VentureLabs IV LLC (\"VentureLabs IV\") holds 684,372 shares of common stock, Flagship VentureLabs V LLC (\"VentureLabs V\") holds 2,645,637 shares of common stock, Flagship Ventures Fund IV L.P. (\"Flagship Fund IV\") holds 1,836,836 shares of common stock, Flagship Ventures Fund IV-Rx, L.P. (\"Flagship Fund IV-Rx\" and, together with VentureLabs IV and Flagship Fund IV, the \"Flagship Fund IV Funds\") holds 448,911 shares of common stock,  Flagship Ventures Fund V, L.P. (\"Flagship Fund V\") holds 4,201,284 shares of common stock, Flagship V VentureLabs Rx Fund, L.P. (\"VentureLabs Rx V\") holds 1,609,871  shares of common stock,  Nutritional Health Side Fund, L.P. (\"Nutritional Health Side Fund\") holds 795,950 shares of common stock,"},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"[Continued] Nutritional Health Disruptive Innovation Fund, L.P. (\"Nutritional Innovation Fund\" and, together with VentureLabs V, Flagship Fund V, VentureLabs Rx V and Nutritional Health Side Fund, the \"Flagship Fund V Funds\") holds 3,598,177 shares of common stock, and Flagship Ventures Opportunities Fund I, L.P. (\"Flagship Opportunities I\" and, together with the Flagship Fund IV Funds and Flagship Fund V Funds, the \"Flagship Funds\") holds 2,412,365 shares of common stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Flagship Fund IV is a member of VentureLabs IV and also serves as its manager. Flagship Fund V is a member of VentureLabs V and also serves as its manager."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The general partner of each of Flagship Fund IV and Flagship Fund IV-Rx is Flagship Ventures Fund IV General Partner LLC (\"Flagship Fund IV GP\"). The general partner of Flagship Fund V, VentureLabs Rx-V, Nutritional Innovation Fund and Nutritional Health Side Fund is Flagship Ventures Fund V General Partner LLC (\"Flagship Fund V GP\"). The general partner of Flagship Opportunities Fund I is Flagship Ventures Opportunities Fund I General Partner LLC (\"Flagship Opportunities GP,\" and together with Flagship Fund IV GP and Flagship Fund V GP, the \"Flagship General Partners\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship Fund IV GP and each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship Fund IV Funds. Dr. Afeyan also serves as the managing member of the Flagship Fund V GP and Flagship Opportunities Fund GP and may be deemed to possess sole voting and investment control over the shares held by the Flagship Fund V Funds and Flagship Opportunities Fund I. Each of the Flagship General Partners, Dr. Afeyan and Mr. Kania  disclaims beneficial ownership of any shares beneficially owned by the Flagship Funds except to the extent of its or his pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":4562664},"source":{"system":"sec-edgar","filing":"0000899243-18-013014","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1694665/000089924318013014/doc4.xml","form_type":"4"}},{"id":3933115,"issuer":{"id":108468,"kind":"organization","name":"Evelo Biosciences, Inc.","symbol":"EVLO"},"owners":[{"id":97142,"kind":"organization","name":"Flagship Ventures Fund IV General Partner LLC","position":1,"cik":"0001508051","reported_name":"Flagship Ventures Fund IV General Partner LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157564,"kind":"organization","name":"Flagship VentureLabs IV, LLC","position":2,"cik":"0001642578","reported_name":"Flagship VentureLabs IV, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":111426,"kind":"organization","name":"Flagship Ventures Fund IV, L.P.","position":3,"cik":"0001503559","reported_name":"Flagship Ventures Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":126697,"kind":"organization","name":"Flagship Ventures Fund IV-Rx, L.P.","position":4,"cik":"0001590973","reported_name":"Flagship Ventures Fund IV-Rx, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A-3 Preferred Stock","published_at":"2018-05-15T20:43:24.000Z","date":"2018-05-11","kind":"exercise","acquired":false,"shares":8333000,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Following the transactions reported herein, Flagship VentureLabs IV LLC (\"VentureLabs IV\") holds 684,372 shares of common stock, Flagship VentureLabs V LLC (\"VentureLabs V\") holds 2,645,637 shares of common stock, Flagship Ventures Fund IV L.P. (\"Flagship Fund IV\") holds 1,836,836 shares of common stock, Flagship Ventures Fund IV-Rx, L.P. (\"Flagship Fund IV-Rx\" and, together with VentureLabs IV and Flagship Fund IV, the \"Flagship Fund IV Funds\") holds 448,911 shares of common stock,  Flagship Ventures Fund V, L.P. (\"Flagship Fund V\") holds 4,201,284 shares of common stock, Flagship V VentureLabs Rx Fund, L.P. (\"VentureLabs Rx V\") holds 1,609,871  shares of common stock,  Nutritional Health Side Fund, L.P. (\"Nutritional Health Side Fund\") holds 795,950 shares of common stock,"},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"[Continued] Nutritional Health Disruptive Innovation Fund, L.P. (\"Nutritional Innovation Fund\" and, together with VentureLabs V, Flagship Fund V, VentureLabs Rx V and Nutritional Health Side Fund, the \"Flagship Fund V Funds\") holds 3,598,177 shares of common stock, and Flagship Ventures Opportunities Fund I, L.P. (\"Flagship Opportunities I\" and, together with the Flagship Fund IV Funds and Flagship Fund V Funds, the \"Flagship Funds\") holds 2,412,365 shares of common stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Flagship Fund IV is a member of VentureLabs IV and also serves as its manager. Flagship Fund V is a member of VentureLabs V and also serves as its manager."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The general partner of each of Flagship Fund IV and Flagship Fund IV-Rx is Flagship Ventures Fund IV General Partner LLC (\"Flagship Fund IV GP\"). The general partner of Flagship Fund V, VentureLabs Rx-V, Nutritional Innovation Fund and Nutritional Health Side Fund is Flagship Ventures Fund V General Partner LLC (\"Flagship Fund V GP\"). The general partner of Flagship Opportunities Fund I is Flagship Ventures Opportunities Fund I General Partner LLC (\"Flagship Opportunities GP,\" and together with Flagship Fund IV GP and Flagship Fund V GP, the \"Flagship General Partners\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship Fund IV GP and each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship Fund IV Funds. Dr. Afeyan also serves as the managing member of the Flagship Fund V GP and Flagship Opportunities Fund GP and may be deemed to possess sole voting and investment control over the shares held by the Flagship Fund V Funds and Flagship Opportunities Fund I. Each of the Flagship General Partners, Dr. Afeyan and Mr. Kania  disclaims beneficial ownership of any shares beneficially owned by the Flagship Funds except to the extent of its or his pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":2042902},"source":{"system":"sec-edgar","filing":"0000899243-18-013014","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1694665/000089924318013014/doc4.xml","form_type":"4"}},{"id":3933114,"issuer":{"id":108468,"kind":"organization","name":"Evelo Biosciences, Inc.","symbol":"EVLO"},"owners":[{"id":97142,"kind":"organization","name":"Flagship Ventures Fund IV General Partner LLC","position":1,"cik":"0001508051","reported_name":"Flagship Ventures Fund IV General Partner LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157564,"kind":"organization","name":"Flagship VentureLabs IV, LLC","position":2,"cik":"0001642578","reported_name":"Flagship VentureLabs IV, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":111426,"kind":"organization","name":"Flagship Ventures Fund IV, L.P.","position":3,"cik":"0001503559","reported_name":"Flagship Ventures Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":126697,"kind":"organization","name":"Flagship Ventures Fund IV-Rx, L.P.","position":4,"cik":"0001590973","reported_name":"Flagship Ventures Fund IV-Rx, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A-2 Preferred Stock","published_at":"2018-05-15T20:43:24.000Z","date":"2018-05-11","kind":"exercise","acquired":false,"shares":5416667,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Following the transactions reported herein, Flagship VentureLabs IV LLC (\"VentureLabs IV\") holds 684,372 shares of common stock, Flagship VentureLabs V LLC (\"VentureLabs V\") holds 2,645,637 shares of common stock, Flagship Ventures Fund IV L.P. (\"Flagship Fund IV\") holds 1,836,836 shares of common stock, Flagship Ventures Fund IV-Rx, L.P. (\"Flagship Fund IV-Rx\" and, together with VentureLabs IV and Flagship Fund IV, the \"Flagship Fund IV Funds\") holds 448,911 shares of common stock,  Flagship Ventures Fund V, L.P. (\"Flagship Fund V\") holds 4,201,284 shares of common stock, Flagship V VentureLabs Rx Fund, L.P. (\"VentureLabs Rx V\") holds 1,609,871  shares of common stock,  Nutritional Health Side Fund, L.P. (\"Nutritional Health Side Fund\") holds 795,950 shares of common stock,"},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"[Continued] Nutritional Health Disruptive Innovation Fund, L.P. (\"Nutritional Innovation Fund\" and, together with VentureLabs V, Flagship Fund V, VentureLabs Rx V and Nutritional Health Side Fund, the \"Flagship Fund V Funds\") holds 3,598,177 shares of common stock, and Flagship Ventures Opportunities Fund I, L.P. (\"Flagship Opportunities I\" and, together with the Flagship Fund IV Funds and Flagship Fund V Funds, the \"Flagship Funds\") holds 2,412,365 shares of common stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Flagship Fund IV is a member of VentureLabs IV and also serves as its manager. Flagship Fund V is a member of VentureLabs V and also serves as its manager."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The general partner of each of Flagship Fund IV and Flagship Fund IV-Rx is Flagship Ventures Fund IV General Partner LLC (\"Flagship Fund IV GP\"). The general partner of Flagship Fund V, VentureLabs Rx-V, Nutritional Innovation Fund and Nutritional Health Side Fund is Flagship Ventures Fund V General Partner LLC (\"Flagship Fund V GP\"). The general partner of Flagship Opportunities Fund I is Flagship Ventures Opportunities Fund I General Partner LLC (\"Flagship Opportunities GP,\" and together with Flagship Fund IV GP and Flagship Fund V GP, the \"Flagship General Partners\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship Fund IV GP and each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship Fund IV Funds. Dr. Afeyan also serves as the managing member of the Flagship Fund V GP and Flagship Opportunities Fund GP and may be deemed to possess sole voting and investment control over the shares held by the Flagship Fund V Funds and Flagship Opportunities Fund I. Each of the Flagship General Partners, Dr. Afeyan and Mr. Kania  disclaims beneficial ownership of any shares beneficially owned by the Flagship Funds except to the extent of its or his pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":1327939},"source":{"system":"sec-edgar","filing":"0000899243-18-013014","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1694665/000089924318013014/doc4.xml","form_type":"4"}},{"id":3933113,"issuer":{"id":108468,"kind":"organization","name":"Evelo Biosciences, Inc.","symbol":"EVLO"},"owners":[{"id":97142,"kind":"organization","name":"Flagship Ventures Fund IV General Partner LLC","position":1,"cik":"0001508051","reported_name":"Flagship Ventures Fund IV General Partner LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157564,"kind":"organization","name":"Flagship VentureLabs IV, LLC","position":2,"cik":"0001642578","reported_name":"Flagship VentureLabs IV, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":111426,"kind":"organization","name":"Flagship Ventures Fund IV, L.P.","position":3,"cik":"0001503559","reported_name":"Flagship Ventures Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":126697,"kind":"organization","name":"Flagship Ventures Fund IV-Rx, L.P.","position":4,"cik":"0001590973","reported_name":"Flagship Ventures Fund IV-Rx, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A-1 Preferred Stock","published_at":"2018-05-15T20:43:24.000Z","date":"2018-05-11","kind":"exercise","acquired":false,"shares":10102055,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Following the transactions reported herein, Flagship VentureLabs IV LLC (\"VentureLabs IV\") holds 684,372 shares of common stock, Flagship VentureLabs V LLC (\"VentureLabs V\") holds 2,645,637 shares of common stock, Flagship Ventures Fund IV L.P. (\"Flagship Fund IV\") holds 1,836,836 shares of common stock, Flagship Ventures Fund IV-Rx, L.P. (\"Flagship Fund IV-Rx\" and, together with VentureLabs IV and Flagship Fund IV, the \"Flagship Fund IV Funds\") holds 448,911 shares of common stock,  Flagship Ventures Fund V, L.P. (\"Flagship Fund V\") holds 4,201,284 shares of common stock, Flagship V VentureLabs Rx Fund, L.P. (\"VentureLabs Rx V\") holds 1,609,871  shares of common stock,  Nutritional Health Side Fund, L.P. (\"Nutritional Health Side Fund\") holds 795,950 shares of common stock,"},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"[Continued] Nutritional Health Disruptive Innovation Fund, L.P. (\"Nutritional Innovation Fund\" and, together with VentureLabs V, Flagship Fund V, VentureLabs Rx V and Nutritional Health Side Fund, the \"Flagship Fund V Funds\") holds 3,598,177 shares of common stock, and Flagship Ventures Opportunities Fund I, L.P. (\"Flagship Opportunities I\" and, together with the Flagship Fund IV Funds and Flagship Fund V Funds, the \"Flagship Funds\") holds 2,412,365 shares of common stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Flagship Fund IV is a member of VentureLabs IV and also serves as its manager. Flagship Fund V is a member of VentureLabs V and also serves as its manager."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The general partner of each of Flagship Fund IV and Flagship Fund IV-Rx is Flagship Ventures Fund IV General Partner LLC (\"Flagship Fund IV GP\"). The general partner of Flagship Fund V, VentureLabs Rx-V, Nutritional Innovation Fund and Nutritional Health Side Fund is Flagship Ventures Fund V General Partner LLC (\"Flagship Fund V GP\"). The general partner of Flagship Opportunities Fund I is Flagship Ventures Opportunities Fund I General Partner LLC (\"Flagship Opportunities GP,\" and together with Flagship Fund IV GP and Flagship Fund V GP, the \"Flagship General Partners\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship Fund IV GP and each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship Fund IV Funds. Dr. Afeyan also serves as the managing member of the Flagship Fund V GP and Flagship Opportunities Fund GP and may be deemed to possess sole voting and investment control over the shares held by the Flagship Fund V Funds and Flagship Opportunities Fund I. Each of the Flagship General Partners, Dr. Afeyan and Mr. Kania  disclaims beneficial ownership of any shares beneficially owned by the Flagship Funds except to the extent of its or his pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":2476600},"source":{"system":"sec-edgar","filing":"0000899243-18-013014","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1694665/000089924318013014/doc4.xml","form_type":"4"}},{"id":3933112,"issuer":{"id":108468,"kind":"organization","name":"Evelo Biosciences, Inc.","symbol":"EVLO"},"owners":[{"id":97142,"kind":"organization","name":"Flagship Ventures Fund IV General Partner LLC","position":1,"cik":"0001508051","reported_name":"Flagship Ventures Fund IV General Partner LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157564,"kind":"organization","name":"Flagship VentureLabs IV, LLC","position":2,"cik":"0001642578","reported_name":"Flagship VentureLabs IV, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":111426,"kind":"organization","name":"Flagship Ventures Fund IV, L.P.","position":3,"cik":"0001503559","reported_name":"Flagship Ventures Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":126697,"kind":"organization","name":"Flagship Ventures Fund IV-Rx, L.P.","position":4,"cik":"0001590973","reported_name":"Flagship Ventures Fund IV-Rx, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A Preferred Stock","published_at":"2018-05-15T20:43:24.000Z","date":"2018-05-11","kind":"exercise","acquired":false,"shares":12536945,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F7","text":"Upon closing of the Issuer's initial public offering, each share of preferred stock was automatically converted into the Issuer's common stock on a 0.2452-for-one basis."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Following the transactions reported herein, Flagship VentureLabs IV LLC (\"VentureLabs IV\") holds 684,372 shares of common stock, Flagship VentureLabs V LLC (\"VentureLabs V\") holds 2,645,637 shares of common stock, Flagship Ventures Fund IV L.P. (\"Flagship Fund IV\") holds 1,836,836 shares of common stock, Flagship Ventures Fund IV-Rx, L.P. (\"Flagship Fund IV-Rx\" and, together with VentureLabs IV and Flagship Fund IV, the \"Flagship Fund IV Funds\") holds 448,911 shares of common stock,  Flagship Ventures Fund V, L.P. (\"Flagship Fund V\") holds 4,201,284 shares of common stock, Flagship V VentureLabs Rx Fund, L.P. (\"VentureLabs Rx V\") holds 1,609,871  shares of common stock,  Nutritional Health Side Fund, L.P. (\"Nutritional Health Side Fund\") holds 795,950 shares of common stock,"},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"[Continued] Nutritional Health Disruptive Innovation Fund, L.P. (\"Nutritional Innovation Fund\" and, together with VentureLabs V, Flagship Fund V, VentureLabs Rx V and Nutritional Health Side Fund, the \"Flagship Fund V Funds\") holds 3,598,177 shares of common stock, and Flagship Ventures Opportunities Fund I, L.P. (\"Flagship Opportunities I\" and, together with the Flagship Fund IV Funds and Flagship Fund V Funds, the \"Flagship Funds\") holds 2,412,365 shares of common stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Flagship Fund IV is a member of VentureLabs IV and also serves as its manager. Flagship Fund V is a member of VentureLabs V and also serves as its manager."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The general partner of each of Flagship Fund IV and Flagship Fund IV-Rx is Flagship Ventures Fund IV General Partner LLC (\"Flagship Fund IV GP\"). The general partner of Flagship Fund V, VentureLabs Rx-V, Nutritional Innovation Fund and Nutritional Health Side Fund is Flagship Ventures Fund V General Partner LLC (\"Flagship Fund V GP\"). The general partner of Flagship Opportunities Fund I is Flagship Ventures Opportunities Fund I General Partner LLC (\"Flagship Opportunities GP,\" and together with Flagship Fund IV GP and Flagship Fund V GP, the \"Flagship General Partners\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship Fund IV GP and each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship Fund IV Funds. Dr. Afeyan also serves as the managing member of the Flagship Fund V GP and Flagship Opportunities Fund GP and may be deemed to possess sole voting and investment control over the shares held by the Flagship Fund V Funds and Flagship Opportunities Fund I. Each of the Flagship General Partners, Dr. Afeyan and Mr. Kania  disclaims beneficial ownership of any shares beneficially owned by the Flagship Funds except to the extent of its or his pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":3073533},"source":{"system":"sec-edgar","filing":"0000899243-18-013014","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1694665/000089924318013014/doc4.xml","form_type":"4"}},{"id":3933111,"issuer":{"id":108468,"kind":"organization","name":"Evelo Biosciences, Inc.","symbol":"EVLO"},"owners":[{"id":97142,"kind":"organization","name":"Flagship Ventures Fund IV General Partner LLC","position":1,"cik":"0001508051","reported_name":"Flagship Ventures Fund IV General Partner LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157564,"kind":"organization","name":"Flagship VentureLabs IV, LLC","position":2,"cik":"0001642578","reported_name":"Flagship VentureLabs IV, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":111426,"kind":"organization","name":"Flagship Ventures Fund IV, L.P.","position":3,"cik":"0001503559","reported_name":"Flagship Ventures Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":126697,"kind":"organization","name":"Flagship Ventures Fund IV-Rx, L.P.","position":4,"cik":"0001590973","reported_name":"Flagship Ventures Fund IV-Rx, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-05-15T20:43:24.000Z","date":"2018-05-11","kind":"purchase","acquired":true,"shares":281250,"price":16,"value":4500000.0,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F6","text":"Includes 35,156, 105,469, and 140,625 shares purchased by Nutritional Health Side Fund, Nutritional Innovation Fund, and  Flagship Opportunities I, respectively, in connection with the Issuer's initial public offering."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Following the transactions reported herein, Flagship VentureLabs IV LLC (\"VentureLabs IV\") holds 684,372 shares of common stock, Flagship VentureLabs V LLC (\"VentureLabs V\") holds 2,645,637 shares of common stock, Flagship Ventures Fund IV L.P. (\"Flagship Fund IV\") holds 1,836,836 shares of common stock, Flagship Ventures Fund IV-Rx, L.P. (\"Flagship Fund IV-Rx\" and, together with VentureLabs IV and Flagship Fund IV, the \"Flagship Fund IV Funds\") holds 448,911 shares of common stock,  Flagship Ventures Fund V, L.P. (\"Flagship Fund V\") holds 4,201,284 shares of common stock, Flagship V VentureLabs Rx Fund, L.P. (\"VentureLabs Rx V\") holds 1,609,871  shares of common stock,  Nutritional Health Side Fund, L.P. (\"Nutritional Health Side Fund\") holds 795,950 shares of common stock,"},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"[Continued] Nutritional Health Disruptive Innovation Fund, L.P. (\"Nutritional Innovation Fund\" and, together with VentureLabs V, Flagship Fund V, VentureLabs Rx V and Nutritional Health Side Fund, the \"Flagship Fund V Funds\") holds 3,598,177 shares of common stock, and Flagship Ventures Opportunities Fund I, L.P. (\"Flagship Opportunities I\" and, together with the Flagship Fund IV Funds and Flagship Fund V Funds, the \"Flagship Funds\") holds 2,412,365 shares of common stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Flagship Fund IV is a member of VentureLabs IV and also serves as its manager. Flagship Fund V is a member of VentureLabs V and also serves as its manager."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The general partner of each of Flagship Fund IV and Flagship Fund IV-Rx is Flagship Ventures Fund IV General Partner LLC (\"Flagship Fund IV GP\"). The general partner of Flagship Fund V, VentureLabs Rx-V, Nutritional Innovation Fund and Nutritional Health Side Fund is Flagship Ventures Fund V General Partner LLC (\"Flagship Fund V GP\"). The general partner of Flagship Opportunities Fund I is Flagship Ventures Opportunities Fund I General Partner LLC (\"Flagship Opportunities GP,\" and together with Flagship Fund IV GP and Flagship Fund V GP, the \"Flagship General Partners\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship Fund IV GP and each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship Fund IV Funds. Dr. Afeyan also serves as the managing member of the Flagship Fund V GP and Flagship Opportunities Fund GP and may be deemed to possess sole voting and investment control over the shares held by the Flagship Fund V Funds and Flagship Opportunities Fund I. Each of the Flagship General Partners, Dr. Afeyan and Mr. Kania  disclaims beneficial ownership of any shares beneficially owned by the Flagship Funds except to the extent of its or his pecuniary interest therein."}],"balance_after":18233403,"source":{"system":"sec-edgar","filing":"0000899243-18-013014","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1694665/000089924318013014/doc4.xml","form_type":"4"}},{"id":3933110,"issuer":{"id":108468,"kind":"organization","name":"Evelo Biosciences, Inc.","symbol":"EVLO"},"owners":[{"id":97142,"kind":"organization","name":"Flagship Ventures Fund IV General Partner LLC","position":1,"cik":"0001508051","reported_name":"Flagship Ventures Fund IV General Partner LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157564,"kind":"organization","name":"Flagship VentureLabs IV, LLC","position":2,"cik":"0001642578","reported_name":"Flagship VentureLabs IV, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":111426,"kind":"organization","name":"Flagship Ventures Fund IV, L.P.","position":3,"cik":"0001503559","reported_name":"Flagship Ventures Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":126697,"kind":"organization","name":"Flagship Ventures Fund IV-Rx, L.P.","position":4,"cik":"0001590973","reported_name":"Flagship Ventures Fund IV-Rx, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-05-15T20:43:24.000Z","date":"2018-05-11","kind":"exercise","acquired":true,"shares":14622143,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Following the transactions reported herein, Flagship VentureLabs IV LLC (\"VentureLabs IV\") holds 684,372 shares of common stock, Flagship VentureLabs V LLC (\"VentureLabs V\") holds 2,645,637 shares of common stock, Flagship Ventures Fund IV L.P. (\"Flagship Fund IV\") holds 1,836,836 shares of common stock, Flagship Ventures Fund IV-Rx, L.P. (\"Flagship Fund IV-Rx\" and, together with VentureLabs IV and Flagship Fund IV, the \"Flagship Fund IV Funds\") holds 448,911 shares of common stock,  Flagship Ventures Fund V, L.P. (\"Flagship Fund V\") holds 4,201,284 shares of common stock, Flagship V VentureLabs Rx Fund, L.P. (\"VentureLabs Rx V\") holds 1,609,871  shares of common stock,  Nutritional Health Side Fund, L.P. (\"Nutritional Health Side Fund\") holds 795,950 shares of common stock,"},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"[Continued] Nutritional Health Disruptive Innovation Fund, L.P. (\"Nutritional Innovation Fund\" and, together with VentureLabs V, Flagship Fund V, VentureLabs Rx V and Nutritional Health Side Fund, the \"Flagship Fund V Funds\") holds 3,598,177 shares of common stock, and Flagship Ventures Opportunities Fund I, L.P. (\"Flagship Opportunities I\" and, together with the Flagship Fund IV Funds and Flagship Fund V Funds, the \"Flagship Funds\") holds 2,412,365 shares of common stock."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Flagship Fund IV is a member of VentureLabs IV and also serves as its manager. Flagship Fund V is a member of VentureLabs V and also serves as its manager."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The general partner of each of Flagship Fund IV and Flagship Fund IV-Rx is Flagship Ventures Fund IV General Partner LLC (\"Flagship Fund IV GP\"). The general partner of Flagship Fund V, VentureLabs Rx-V, Nutritional Innovation Fund and Nutritional Health Side Fund is Flagship Ventures Fund V General Partner LLC (\"Flagship Fund V GP\"). The general partner of Flagship Opportunities Fund I is Flagship Ventures Opportunities Fund I General Partner LLC (\"Flagship Opportunities GP,\" and together with Flagship Fund IV GP and Flagship Fund V GP, the \"Flagship General Partners\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship Fund IV GP and each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship Fund IV Funds. Dr. Afeyan also serves as the managing member of the Flagship Fund V GP and Flagship Opportunities Fund GP and may be deemed to possess sole voting and investment control over the shares held by the Flagship Fund V Funds and Flagship Opportunities Fund I. Each of the Flagship General Partners, Dr. Afeyan and Mr. Kania  disclaims beneficial ownership of any shares beneficially owned by the Flagship Funds except to the extent of its or his pecuniary interest therein."}],"balance_after":17952153,"source":{"system":"sec-edgar","filing":"0000899243-18-013014","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1694665/000089924318013014/doc4.xml","form_type":"4"}},{"id":4228433,"issuer":{"id":85437,"kind":"organization","name":"Syros Pharmaceuticals, Inc.","symbol":"SYRS"},"owners":[{"id":111426,"kind":"organization","name":"Flagship Ventures Fund IV, L.P.","position":1,"cik":"0001503559","reported_name":"Flagship Ventures Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":126697,"kind":"organization","name":"Flagship Ventures Fund IV-Rx, L.P.","position":2,"cik":"0001590973","reported_name":"Flagship Ventures Fund IV-Rx, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157564,"kind":"organization","name":"Flagship VentureLabs IV, LLC","position":3,"cik":"0001642578","reported_name":"Flagship VentureLabs IV, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":97142,"kind":"organization","name":"Flagship Ventures Fund IV General Partner LLC","position":4,"cik":"0001508051","reported_name":"Flagship Ventures Fund IV General Partner LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":44731,"kind":"person","name":"Afeyan Noubar","position":5,"cik":"0001222012","reported_name":"AFEYAN NOUBAR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":44658,"kind":"person","name":"Kania Edwin","position":6,"cik":"0001255927","reported_name":"KANIA EDWIN M JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-08-21T20:19:58.000Z","date":"2017-08-17","kind":"other","acquired":false,"shares":54293,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"On August 17, 2017, Flagship Ventures Fund IV, L.P. (\"Flagship IV\") and Flagship Ventures Fund IV-Rx, L.P. (\"Flagship IV-Rx\") distributed to its limited partners and sole general partner, Flagship Ventures Fund IV General Partner, LLC (\"Flagship IV LLC\"), pro rata and without consideration, 1,295,997 shares and 306,222 shares, respectively, of the Issuer's common stock.  Flagship IV LLC, in turn, distributed to its members, pro rata and without consideration, the 54,283 shares and 10 shares it received from Flagship IV and Flagship IV-Rx, respectively.  Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr., each a manager of Flagship IV LLC, each received 24,527 shares through Flagship IV LLC's distribution."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On August 17, 2017, Flagship Ventures Fund IV, L.P. (\"Flagship IV\") and Flagship Ventures Fund IV-Rx, L.P. (\"Flagship IV-Rx\") distributed to its limited partners and sole general partner, Flagship Ventures Fund IV General Partner, LLC (\"Flagship IV LLC\"), pro rata and without consideration, 1,295,997 shares and 306,222 shares, respectively, of the Issuer's common stock.  Flagship IV LLC, in turn, distributed to its members, pro rata and without consideration, the 54,283 shares and 10 shares it received from Flagship IV and Flagship IV-Rx, respectively.  Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr., each a manager of Flagship IV LLC, each received 24,527 shares through Flagship IV LLC's distribution."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"On August 17, 2017, Flagship Ventures Fund IV, L.P. (\"Flagship IV\") and Flagship Ventures Fund IV-Rx, L.P. (\"Flagship IV-Rx\") distributed to its limited partners and sole general partner, Flagship Ventures Fund IV General Partner, LLC (\"Flagship IV LLC\"), pro rata and without consideration, 1,295,997 shares and 306,222 shares, respectively, of the Issuer's common stock.  Flagship IV LLC, in turn, distributed to its members, pro rata and without consideration, the 54,283 shares and 10 shares it received from Flagship IV and Flagship IV-Rx, respectively.  Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr., each a manager of Flagship IV LLC, each received 24,527 shares through Flagship IV LLC's distribution."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Held by Flagship IV LLC.  Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship IV LLC. Each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship IV LLC.  Each of the filing persons other than Flagship IV LLC disclaims beneficial ownership of the shares except to the extent of his or its pecuniary interest therein."}],"balance_after":0,"source":{"system":"sec-edgar","filing":"0001012975-17-000639","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1222012/000101297517000639/edgar.xml","form_type":"4"}},{"id":4228432,"issuer":{"id":85437,"kind":"organization","name":"Syros Pharmaceuticals, Inc.","symbol":"SYRS"},"owners":[{"id":111426,"kind":"organization","name":"Flagship Ventures Fund IV, L.P.","position":1,"cik":"0001503559","reported_name":"Flagship Ventures Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":126697,"kind":"organization","name":"Flagship Ventures Fund IV-Rx, L.P.","position":2,"cik":"0001590973","reported_name":"Flagship Ventures Fund IV-Rx, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157564,"kind":"organization","name":"Flagship VentureLabs IV, LLC","position":3,"cik":"0001642578","reported_name":"Flagship VentureLabs IV, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":97142,"kind":"organization","name":"Flagship Ventures Fund IV General Partner LLC","position":4,"cik":"0001508051","reported_name":"Flagship Ventures Fund IV General Partner LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":44731,"kind":"person","name":"Afeyan Noubar","position":5,"cik":"0001222012","reported_name":"AFEYAN NOUBAR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":44658,"kind":"person","name":"Kania Edwin","position":6,"cik":"0001255927","reported_name":"KANIA EDWIN M JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-08-21T20:19:58.000Z","date":"2017-08-17","kind":"other","acquired":false,"shares":306222,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"On August 17, 2017, Flagship Ventures Fund IV, L.P. (\"Flagship IV\") and Flagship Ventures Fund IV-Rx, L.P. (\"Flagship IV-Rx\") distributed to its limited partners and sole general partner, Flagship Ventures Fund IV General Partner, LLC (\"Flagship IV LLC\"), pro rata and without consideration, 1,295,997 shares and 306,222 shares, respectively, of the Issuer's common stock.  Flagship IV LLC, in turn, distributed to its members, pro rata and without consideration, the 54,283 shares and 10 shares it received from Flagship IV and Flagship IV-Rx, respectively.  Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr., each a manager of Flagship IV LLC, each received 24,527 shares through Flagship IV LLC's distribution."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On August 17, 2017, Flagship Ventures Fund IV, L.P. (\"Flagship IV\") and Flagship Ventures Fund IV-Rx, L.P. (\"Flagship IV-Rx\") distributed to its limited partners and sole general partner, Flagship Ventures Fund IV General Partner, LLC (\"Flagship IV LLC\"), pro rata and without consideration, 1,295,997 shares and 306,222 shares, respectively, of the Issuer's common stock.  Flagship IV LLC, in turn, distributed to its members, pro rata and without consideration, the 54,283 shares and 10 shares it received from Flagship IV and Flagship IV-Rx, respectively.  Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr., each a manager of Flagship IV LLC, each received 24,527 shares through Flagship IV LLC's distribution."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Held by Flagship IV-Rx.  Flagship IV LLC is the general partner of Flagship IV-Rx.  Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship IV LLC. Flagship IV LLC and each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship IV-Rx.  Each of the filing persons other than Flagship IV-Rx disclaims beneficial ownership of the shares except to the extent of his or its pecuniary interest therein."}],"balance_after":612442,"source":{"system":"sec-edgar","filing":"0001012975-17-000639","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1222012/000101297517000639/edgar.xml","form_type":"4"}},{"id":4228431,"issuer":{"id":85437,"kind":"organization","name":"Syros Pharmaceuticals, Inc.","symbol":"SYRS"},"owners":[{"id":111426,"kind":"organization","name":"Flagship Ventures Fund IV, L.P.","position":1,"cik":"0001503559","reported_name":"Flagship Ventures Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":126697,"kind":"organization","name":"Flagship Ventures Fund IV-Rx, L.P.","position":2,"cik":"0001590973","reported_name":"Flagship Ventures Fund IV-Rx, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":157564,"kind":"organization","name":"Flagship VentureLabs IV, LLC","position":3,"cik":"0001642578","reported_name":"Flagship VentureLabs IV, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":97142,"kind":"organization","name":"Flagship Ventures Fund IV General Partner LLC","position":4,"cik":"0001508051","reported_name":"Flagship Ventures Fund IV General Partner LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":44731,"kind":"person","name":"Afeyan Noubar","position":5,"cik":"0001222012","reported_name":"AFEYAN NOUBAR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":44658,"kind":"person","name":"Kania Edwin","position":6,"cik":"0001255927","reported_name":"KANIA EDWIN M JR","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-08-21T20:19:58.000Z","date":"2017-08-17","kind":"other","acquired":false,"shares":1295997,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"On August 17, 2017, Flagship Ventures Fund IV, L.P. (\"Flagship IV\") and Flagship Ventures Fund IV-Rx, L.P. (\"Flagship IV-Rx\") distributed to its limited partners and sole general partner, Flagship Ventures Fund IV General Partner, LLC (\"Flagship IV LLC\"), pro rata and without consideration, 1,295,997 shares and 306,222 shares, respectively, of the Issuer's common stock.  Flagship IV LLC, in turn, distributed to its members, pro rata and without consideration, the 54,283 shares and 10 shares it received from Flagship IV and Flagship IV-Rx, respectively.  Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr., each a manager of Flagship IV LLC, each received 24,527 shares through Flagship IV LLC's distribution."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On August 17, 2017, Flagship Ventures Fund IV, L.P. (\"Flagship IV\") and Flagship Ventures Fund IV-Rx, L.P. (\"Flagship IV-Rx\") distributed to its limited partners and sole general partner, Flagship Ventures Fund IV General Partner, LLC (\"Flagship IV LLC\"), pro rata and without consideration, 1,295,997 shares and 306,222 shares, respectively, of the Issuer's common stock.  Flagship IV LLC, in turn, distributed to its members, pro rata and without consideration, the 54,283 shares and 10 shares it received from Flagship IV and Flagship IV-Rx, respectively.  Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr., each a manager of Flagship IV LLC, each received 24,527 shares through Flagship IV LLC's distribution."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"Held by Flagship IV.  Flagship IV LLC is the general partner of Flagship IV.  Noubar B. Afeyan, Ph.D. and Edwin M. Kania, Jr. are the managers of Flagship IV LLC. Flagship IV LLC and each of these individuals may be deemed to share voting and investment power with respect to all shares held by Flagship IV.  Each of the filing persons other than Flagship IV disclaims beneficial ownership of the shares except to the extent of his or its pecuniary interest therein."}],"balance_after":2378663,"source":{"system":"sec-edgar","filing":"0001012975-17-000639","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1222012/000101297517000639/edgar.xml","form_type":"4"}}]}