{"transactions":[{"id":3480380,"issuer":{"id":75335,"kind":"organization","name":"DURECT CORP","symbol":"DRRX"},"owners":[{"id":50349,"kind":"organization","name":"First Eagle Investment Management, LLC","position":1,"cik":"0001325447","reported_name":"First Eagle Investment Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156513,"kind":"organization","name":"21 APRIL FUND, L.P.","position":2,"cik":"0001459688","reported_name":"21 APRIL FUND, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":154711,"kind":"organization","name":"21 APRIL FUND, LTD.","position":3,"cik":"0001459708","reported_name":"21 APRIL FUND, LTD.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156514,"kind":"organization","name":"First Eagle Value in Biotechnology Master Fund, Ltd.","position":4,"cik":"0001457518","reported_name":"First Eagle Value in Biotechnology Master Fund, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":93499,"kind":"organization","name":"First Eagle Holdings, Inc.","position":5,"cik":"0001637141","reported_name":"First Eagle Holdings, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2019-06-24T14:12:39.000Z","date":"2019-06-20","kind":"purchase","acquired":true,"shares":4000000,"price":0.52,"value":2080000.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"This Form 4 is filed by 21 April Fund, LP (\"April LP\"), 21 April Ltd. (\"April Ltd.\"), First Eagle Investment Management, LLC (\"FEIM\"), First Eagle Value in Biotechnology Master Fund, Ltd. (\"FEVIBM\") and First Eagle Holdings, Inc. (\"FEHI\" and, collectively with April LP, April Ltd., FEIM and FEVIBM, the \"Entities\"). The Entities disclaim status as a \"group\" for purposes of this Form 4."},{"field":"shares","element":"transactionShares","label":"F2","text":"Pursuant to a prospectus supplement, dated June 20, 2019,  DURECT Corporation (the \"Company\") offered 29,000,000 shares of its common stock, par value $0.0001 per share (the \"Common Stock\") to certain investors of the Company.  Pursuant to the terms that certain Securities Purchase Agreement, dated June 20, 2019, by and among the Company, April LP, April Ltd. and certain other persons, April LP and April Ltd purchased an aggregate of 4,000,000 shares of the Common Stock of the 29,000,000 made available in the offering at a price of $0.52 per share.   The 4,000,000 shares of Common Stock represent 1,300,000 shares of Common Stock directly held by April LP and 2,700,000 shares of Common Stock directly held by April Ltd."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"Represents 4,726,893, 16,067,709, 5,586,944 and 95,000 shares of Common Stock held directly by 21 April LP, 21 April Ltd., FEVIBM and certain separately managed accounts, including accounts for which FEIM serves as registered investment adviser (the \"Separately Managed Accounts\"), respectively."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The shares of Common Stock reported herein are indirectly beneficially owned by FEHI and FEIM, a Delaware limited liability company and an investment adviser registered under the Investment Advisers Act of 1940. FEIM is (i) a general partner of April LP, (ii) the registered investment adviser to FEVIBM as well as to April LP and April Ltd. (collectively, the \"Funds\"), (iii) a subsidiary of FEHI and (iv) the investment adviser to certain of the Separately Managed Accounts. FEHI disclaims beneficial ownership of the shares of Common Stock held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the beneficial owner of any such securities."}],"balance_after":26476546,"source":{"system":"sec-edgar","filing":"0001567619-19-013856","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1082038/000156761919013856/doc1.xml","form_type":"4"}},{"id":3540683,"issuer":{"id":155143,"kind":"organization","name":"ARADIGM CORP","symbol":"ARDM"},"owners":[{"id":50349,"kind":"organization","name":"First Eagle Investment Management, LLC","position":1,"cik":"0001325447","reported_name":"First Eagle Investment Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":154711,"kind":"organization","name":"21 APRIL FUND, LTD.","position":2,"cik":"0001459708","reported_name":"21 APRIL FUND, LTD.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156514,"kind":"organization","name":"First Eagle Value in Biotechnology Master Fund, Ltd.","position":3,"cik":"0001457518","reported_name":"First Eagle Value in Biotechnology Master Fund, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156513,"kind":"organization","name":"21 APRIL FUND, L.P.","position":4,"cik":"0001459688","reported_name":"21 APRIL FUND, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"9.0% Senior Convertible Notes due 2021","published_at":"2019-05-03T16:30:21.000Z","date":"2019-05-01","kind":"other","acquired":true,"shares":85997,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"See Exhibit 99.1."},{"field":"security","element":"securityTitle","label":"F4","text":"See Exhibit 99.1."},{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F5","text":"See Exhibit 99.1."},{"field":"kind","element":"transactionCoding","label":"F7","text":"See Exhibit 99.1."},{"field":"shares","element":"transactionShares","label":"F5","text":"See Exhibit 99.1."},{"field":"shares","element":"transactionShares","label":"F7","text":"See Exhibit 99.1."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"See Exhibit 99.1."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F5","text":"See Exhibit 99.1."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F5","text":"See Exhibit 99.1."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"See Exhibit 99.1."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"See Exhibit 99.1."}],"balance_after":3362072,"derivative":{"expiration_date":"2021-04-30","underlying":"Common Stock","underlying_shares":16505},"source":{"system":"sec-edgar","filing":"0001567619-19-009760","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1013238/000156761919009760/doc1.xml","form_type":"4"}},{"id":3774737,"issuer":{"id":155143,"kind":"organization","name":"ARADIGM CORP","symbol":"ARDM"},"owners":[{"id":50349,"kind":"organization","name":"First Eagle Investment Management, LLC","position":1,"cik":"0001325447","reported_name":"First Eagle Investment Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":154711,"kind":"organization","name":"21 APRIL FUND, LTD.","position":2,"cik":"0001459708","reported_name":"21 APRIL FUND, LTD.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156514,"kind":"organization","name":"First Eagle Value in Biotechnology Master Fund, Ltd.","position":3,"cik":"0001457518","reported_name":"First Eagle Value in Biotechnology Master Fund, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156513,"kind":"organization","name":"21 APRIL FUND, L.P.","position":4,"cik":"0001459688","reported_name":"21 APRIL FUND, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"9.0% Senior Convertible Notes due 2021","published_at":"2018-11-05T13:52:41.000Z","date":"2018-11-01","kind":"other","acquired":true,"shares":141076,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"See Exhibit 99.1."},{"field":"security","element":"securityTitle","label":"F4","text":"See Exhibit 99.1."},{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F5","text":"See Exhibit 99.1."},{"field":"kind","element":"transactionCoding","label":"F7","text":"See Exhibit 99.1."},{"field":"shares","element":"transactionShares","label":"F5","text":"See Exhibit 99.1."},{"field":"shares","element":"transactionShares","label":"F7","text":"See Exhibit 99.1."},{"field":"price","element":"transactionPricePerShare","label":"F7","text":"See Exhibit 99.1."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"See Exhibit 99.1."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F5","text":"See Exhibit 99.1."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F5","text":"See Exhibit 99.1."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"See Exhibit 99.1."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"See Exhibit 99.1."}],"balance_after":3276076,"derivative":{"expiration_date":"2021-04-30","underlying":"Common Stock","underlying_shares":27076},"source":{"system":"sec-edgar","filing":"0001567619-18-005067","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1013238/000156761918005067/doc1.xml","form_type":"4"}},{"id":3950082,"issuer":{"id":155143,"kind":"organization","name":"ARADIGM CORP","symbol":"ARDM"},"owners":[{"id":50349,"kind":"organization","name":"First Eagle Investment Management, LLC","position":1,"cik":"0001325447","reported_name":"First Eagle Investment Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":154711,"kind":"organization","name":"21 APRIL FUND, LTD.","position":2,"cik":"0001459708","reported_name":"21 APRIL FUND, LTD.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156514,"kind":"organization","name":"First Eagle Value in Biotechnology Master Fund, Ltd.","position":3,"cik":"0001457518","reported_name":"First Eagle Value in Biotechnology Master Fund, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156513,"kind":"organization","name":"21 APRIL FUND, L.P.","position":4,"cik":"0001459688","reported_name":"21 APRIL FUND, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"9.0% Senior Convertible Notes due 2021","published_at":"2018-05-02T16:45:30.000Z","date":"2018-05-01","kind":"other","acquired":true,"shares":25913,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"See Exhibit 99.1"},{"field":"security","element":"securityTitle","label":"F4","text":"See Exhibit 99.1"},{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F5","text":"See Exhibit 99.1"},{"field":"kind","element":"transactionCoding","label":"F7","text":"See Exhibit 99.1"},{"field":"shares","element":"transactionShares","label":"F7","text":"See Exhibit 99.1"},{"field":"price","element":"transactionPricePerShare","label":"F7","text":"See Exhibit 99.1"},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F6","text":"See Exhibit 99.1"},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F5","text":"See Exhibit 99.1"},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F5","text":"See Exhibit 99.1"},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"See Exhibit 99.1"},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"See Exhibit 99.1"}],"balance_after":3135000,"derivative":{"expiration_date":"2021-04-30","underlying":"Common Stock","underlying_shares":601728},"source":{"system":"sec-edgar","filing":"0001140361-18-021276","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1013238/000114036118021276/doc1.xml","form_type":"4"}},{"id":4079996,"issuer":{"id":155143,"kind":"organization","name":"ARADIGM CORP","symbol":"ARDM"},"owners":[{"id":50349,"kind":"organization","name":"First Eagle Investment Management, LLC","position":1,"cik":"0001325447","reported_name":"First Eagle Investment Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":154711,"kind":"organization","name":"21 APRIL FUND, LTD.","position":2,"cik":"0001459708","reported_name":"21 APRIL FUND, LTD.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156514,"kind":"organization","name":"First Eagle Value in Biotechnology Master Fund, Ltd.","position":3,"cik":"0001457518","reported_name":"First Eagle Value in Biotechnology Master Fund, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156513,"kind":"organization","name":"21 APRIL FUND, L.P.","position":4,"cik":"0001459688","reported_name":"21 APRIL FUND, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-02-02T17:33:00.000Z","date":"2018-02-01","kind":"other","acquired":false,"shares":479477,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"This Form 4 is filed by 21 April Fund, LP (\"April LP\"), 21 April Ltd. (\"April Ltd.\"), First Eagle Investment Management, LLC (\"FEIM\"), First Eagle Value in Biotechnology Master Fund, Ltd. (\"FEVIBM\") and First Eagle Holdings, Inc. (\"FEHI\" and, collectively with April LP, April Ltd., FEIM and FEVIBM, the \"Entities\"). The Entities disclaim status as a \"group\" for purposes of this Form 4."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"As of February 1, 2018, certain separately managed accounts terminated their relationship with, and are no longer advised by, FEIM. The positions held in such accounts are therefore no longer included herein."},{"field":"acquired","element":"transactionAcquiredDisposedCode","label":"F2","text":"As of February 1, 2018, certain separately managed accounts terminated their relationship with, and are no longer advised by, FEIM. The positions held in such accounts are therefore no longer included herein."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The shares of Common Stock reported herein are indirectly beneficially owned by FEHI and FEIM, a Delaware limited liability company and an investment adviser registered under the Investment Advisers Act of 1940. FEIM is (i) a general partner of April LP, (ii) the registered investment adviser to FEVIBM as well as to April LP and April Ltd. (collectively, the \"Funds\"), (iii) a subsidiary of FEHI and (iv) FEIM is investment adviser to certain of the Separately Managed Accounts. FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."}],"balance_after":4210186,"source":{"system":"sec-edgar","filing":"0001140361-18-004826","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1013238/000114036118004826/doc1.xml","form_type":"4"}},{"id":4531977,"issuer":{"id":155143,"kind":"organization","name":"ARADIGM CORP","symbol":"ARDM"},"owners":[{"id":50349,"kind":"organization","name":"First Eagle Investment Management, LLC","position":1,"cik":"0001325447","reported_name":"First Eagle Investment Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":154711,"kind":"organization","name":"21 APRIL FUND, LTD.","position":2,"cik":"0001459708","reported_name":"21 APRIL FUND, LTD.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156513,"kind":"organization","name":"21 APRIL FUND, L.P.","position":3,"cik":"0001459688","reported_name":"21 APRIL FUND, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156514,"kind":"organization","name":"First Eagle Value in Biotechnology Master Fund, Ltd.","position":4,"cik":"0001457518","reported_name":"First Eagle Value in Biotechnology Master Fund, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Warrants to purchase Common Stock (right to buy)","published_at":"2016-12-06T17:13:53.000Z","date":"2016-12-02","kind":"purchase","acquired":true,"shares":259117,"price":5.21,"value":1349999.57,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"See Exhibit 99.1."},{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F2","text":"See Exhibit 99.1."},{"field":"shares","element":"transactionShares","label":"F3","text":"See Exhibit 99.1."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"See Exhibit 99.1."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"See Exhibit 99.1."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F3","text":"See Exhibit 99.1."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"See Exhibit 99.1."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"See Exhibit 99.1."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"See Exhibit 99.1."}],"balance_after":259117,"derivative":{"exercise_price":5.21,"exercise_date":"2017-01-10","expiration_date":"2021-07-14","underlying":"Common Stock","underlying_shares":259117},"source":{"system":"sec-edgar","filing":"0001140361-16-088916","document":"doc1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1013238/000114036116088916/doc1.xml","form_type":"4"}},{"id":4566907,"issuer":{"id":75335,"kind":"organization","name":"DURECT CORP","symbol":"DRRX"},"owners":[{"id":50349,"kind":"organization","name":"First Eagle Investment Management, LLC","position":1,"cik":"0001325447","reported_name":"First Eagle Investment Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156513,"kind":"organization","name":"21 APRIL FUND, L.P.","position":2,"cik":"0001459688","reported_name":"21 APRIL FUND, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":154711,"kind":"organization","name":"21 APRIL FUND, LTD.","position":3,"cik":"0001459708","reported_name":"21 APRIL FUND, LTD.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156514,"kind":"organization","name":"First Eagle Value in Biotechnology Master Fund, Ltd.","position":4,"cik":"0001457518","reported_name":"First Eagle Value in Biotechnology Master Fund, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":93499,"kind":"organization","name":"First Eagle Holdings, Inc.","position":5,"cik":"0001637141","reported_name":"First Eagle Holdings, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2016-11-04T15:43:39.000Z","date":"2016-11-03","kind":"purchase","acquired":true,"shares":20000,"price":1.14,"value":22800.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"These shares are indirectly beneficially owned by certain separately managed accounts, including accounts for which FEIM serves as registered investment adviser (the \"Separately Managed Accounts\")."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"The shares of Common Stock reported herein are indirectly beneficially owned by FEHI and FEIM, a Delaware limited liability company and an investment adviser registered under the Investment Advisers Act of 1940.  FEIM is (i) a general partner of April LP, (ii) the registered investment adviser to FEVIBM as well as to April LP and April Ltd. (collectively, the \"Funds\"), (iii) a subsidiary of FEHI and (iv) FEIM is investment adviser to certain of the Separately Managed Accounts. FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Represents 3,426,893, 13,367,709, 5,586,944 and 95,000 shares held directly by 21 April LP, 21 April Ltd., FEVIBM and the Separately Managed Accounts, respectively. FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."}],"balance_after":22476546,"source":{"system":"sec-edgar","filing":"0001140361-16-084885","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1082038/000114036116084885/doc1.xml","form_type":"4"}},{"id":4566906,"issuer":{"id":75335,"kind":"organization","name":"DURECT CORP","symbol":"DRRX"},"owners":[{"id":50349,"kind":"organization","name":"First Eagle Investment Management, LLC","position":1,"cik":"0001325447","reported_name":"First Eagle Investment Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156513,"kind":"organization","name":"21 APRIL FUND, L.P.","position":2,"cik":"0001459688","reported_name":"21 APRIL FUND, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":154711,"kind":"organization","name":"21 APRIL FUND, LTD.","position":3,"cik":"0001459708","reported_name":"21 APRIL FUND, LTD.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156514,"kind":"organization","name":"First Eagle Value in Biotechnology Master Fund, Ltd.","position":4,"cik":"0001457518","reported_name":"First Eagle Value in Biotechnology Master Fund, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":93499,"kind":"organization","name":"First Eagle Holdings, Inc.","position":5,"cik":"0001637141","reported_name":"First Eagle Holdings, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2016-11-04T15:43:39.000Z","date":"2016-11-03","kind":"purchase","acquired":true,"shares":25000,"price":1.1399,"value":28497.5,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"These shares are indirectly beneficially owned by certain separately managed accounts, including accounts for which FEIM serves as registered investment adviser (the \"Separately Managed Accounts\")."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"The shares of Common Stock reported herein are indirectly beneficially owned by FEHI and FEIM, a Delaware limited liability company and an investment adviser registered under the Investment Advisers Act of 1940.  FEIM is (i) a general partner of April LP, (ii) the registered investment adviser to FEVIBM as well as to April LP and April Ltd. (collectively, the \"Funds\"), (iii) a subsidiary of FEHI and (iv) FEIM is investment adviser to certain of the Separately Managed Accounts. FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Represents 3,426,893, 13,367,709, 5,586,944 and 75,000 shares held directly by 21 April LP, 21 April Ltd., FEVIBM and the Separately Managed Accounts, respectively. FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."}],"balance_after":22456546,"source":{"system":"sec-edgar","filing":"0001140361-16-084885","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1082038/000114036116084885/doc1.xml","form_type":"4"}},{"id":4566905,"issuer":{"id":75335,"kind":"organization","name":"DURECT CORP","symbol":"DRRX"},"owners":[{"id":50349,"kind":"organization","name":"First Eagle Investment Management, LLC","position":1,"cik":"0001325447","reported_name":"First Eagle Investment Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156513,"kind":"organization","name":"21 APRIL FUND, L.P.","position":2,"cik":"0001459688","reported_name":"21 APRIL FUND, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":154711,"kind":"organization","name":"21 APRIL FUND, LTD.","position":3,"cik":"0001459708","reported_name":"21 APRIL FUND, LTD.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156514,"kind":"organization","name":"First Eagle Value in Biotechnology Master Fund, Ltd.","position":4,"cik":"0001457518","reported_name":"First Eagle Value in Biotechnology Master Fund, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":93499,"kind":"organization","name":"First Eagle Holdings, Inc.","position":5,"cik":"0001637141","reported_name":"First Eagle Holdings, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2016-11-04T15:43:39.000Z","date":"2016-11-03","kind":"purchase","acquired":true,"shares":50000,"price":1.18,"value":59000.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"This Form 4 is filed by 21 April Fund, LP (\"April LP\"), 21 April Ltd. (\"April Ltd.\"), First Eagle Investment Management, LLC (\"FEIM\"), First Eagle Value in Biotechnology Master Fund, Ltd. (\"FEVIBM\") and First Eagle Holdings, Inc. (\"FEHI\" and, collectively with April LP, April Ltd., FEIM and FEVIBM, the \"Entities\"). The Entities disclaim status as a \"group\" for purposes of this Form 4."},{"field":"shares","element":"transactionShares","label":"F2","text":"These shares are indirectly beneficially owned by certain separately managed accounts, including accounts for which FEIM serves as registered investment adviser (the \"Separately Managed Accounts\")."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"The shares of Common Stock reported herein are indirectly beneficially owned by FEHI and FEIM, a Delaware limited liability company and an investment adviser registered under the Investment Advisers Act of 1940.  FEIM is (i) a general partner of April LP, (ii) the registered investment adviser to FEVIBM as well as to April LP and April Ltd. (collectively, the \"Funds\"), (iii) a subsidiary of FEHI and (iv) FEIM is investment adviser to certain of the Separately Managed Accounts. FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Represents 3,426,893, 13,367,709, 5,586,944 and 50,000 shares held directly by 21 April LP, 21 April Ltd., FEVIBM and the Separately Managed Accounts, respectively. FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."}],"balance_after":22431546,"source":{"system":"sec-edgar","filing":"0001140361-16-084885","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1082038/000114036116084885/doc1.xml","form_type":"4"}},{"id":4593588,"issuer":{"id":75335,"kind":"organization","name":"DURECT CORP","symbol":"DRRX"},"owners":[{"id":154711,"kind":"organization","name":"21 APRIL FUND, LTD.","position":1,"cik":"0001459708","reported_name":"21 APRIL FUND, LTD.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156513,"kind":"organization","name":"21 APRIL FUND, L.P.","position":2,"cik":"0001459688","reported_name":"21 APRIL FUND, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156514,"kind":"organization","name":"First Eagle Value in Biotechnology Master Fund, Ltd.","position":3,"cik":"0001457518","reported_name":"First Eagle Value in Biotechnology Master Fund, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":93499,"kind":"organization","name":"First Eagle Holdings, Inc.","position":4,"cik":"0001637141","reported_name":"First Eagle Holdings, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2016-09-28T12:47:51.000Z","date":"2016-09-26","kind":"purchase","acquired":true,"shares":200000,"price":1.15,"value":230000.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F5","text":"Represents 40,809 and 159,191 shares purchased by 21 April LP and 21 April Ltd., respectively. FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F6","text":"Represents 3,426,893, 13,367,709, and 5,586,944 shares held directly by 21 April LP, 21 April Ltd. and FEVIBM, respectively. FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."}],"balance_after":22381546,"source":{"system":"sec-edgar","filing":"0001140361-16-080886","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1082038/000114036116080886/doc1.xml","form_type":"4"}},{"id":4593587,"issuer":{"id":75335,"kind":"organization","name":"DURECT CORP","symbol":"DRRX"},"owners":[{"id":154711,"kind":"organization","name":"21 APRIL FUND, LTD.","position":1,"cik":"0001459708","reported_name":"21 APRIL FUND, LTD.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156513,"kind":"organization","name":"21 APRIL FUND, L.P.","position":2,"cik":"0001459688","reported_name":"21 APRIL FUND, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156514,"kind":"organization","name":"First Eagle Value in Biotechnology Master Fund, Ltd.","position":3,"cik":"0001457518","reported_name":"First Eagle Value in Biotechnology Master Fund, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":93499,"kind":"organization","name":"First Eagle Holdings, Inc.","position":4,"cik":"0001637141","reported_name":"First Eagle Holdings, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2016-09-28T12:47:51.000Z","date":"2016-09-26","kind":"purchase","acquired":true,"shares":318776,"price":1.1,"value":350653.6,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F3","text":"Represents 63,678 and 255,098 shares purchased by 21 April LP and 21 April Ltd., respectively. FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F4","text":"Represents 3,386,084, 13,208,518, and 5,586,944 shares held directly by 21 April LP, 21 April Ltd. and FEVIBM, respectively. FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."}],"balance_after":22181546,"source":{"system":"sec-edgar","filing":"0001140361-16-080886","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1082038/000114036116080886/doc1.xml","form_type":"4"}},{"id":4593586,"issuer":{"id":75335,"kind":"organization","name":"DURECT CORP","symbol":"DRRX"},"owners":[{"id":154711,"kind":"organization","name":"21 APRIL FUND, LTD.","position":1,"cik":"0001459708","reported_name":"21 APRIL FUND, LTD.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156513,"kind":"organization","name":"21 APRIL FUND, L.P.","position":2,"cik":"0001459688","reported_name":"21 APRIL FUND, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":156514,"kind":"organization","name":"First Eagle Value in Biotechnology Master Fund, Ltd.","position":3,"cik":"0001457518","reported_name":"First Eagle Value in Biotechnology Master Fund, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":93499,"kind":"organization","name":"First Eagle Holdings, Inc.","position":4,"cik":"0001637141","reported_name":"First Eagle Holdings, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2016-09-28T12:47:51.000Z","date":"2016-09-26","kind":"purchase","acquired":true,"shares":1981224,"price":1.16,"value":2298219.84,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Represents 259,957 and 1,721,267 shares purchased by 21 April Fund, LP (\"21 April LP\") and 21 April Fund, Ltd. (\"21 April Ltd.\"), respectively. First Eagle Investment Management, LLC (\"FEIM\") is (i) a general partner of 21 April LP, (ii) the registered investment adviser to First Eagle Value in Biotechnology Master Fund, Ltd. \"FEVIBM\" as well as to 21 April LP and 21 April Ltd. (collectively, the \"Funds\") and (iii) a subsidiary of First Eagle Holdings, Inc. (\"FEHI\"). FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"Represents 3,322,406, 12,953,420, and 5,586,944 shares held directly by 21 April LP, 21 April Ltd. and FEVIBM, respectively. FEHI disclaims Section 16 beneficial ownership of the shares held directly by the Funds except to the extent, if any, of its pecuniary interest therein, and this report shall not be deemed an admission that FEHI is the Section 16 beneficial owner of any such securities."}],"balance_after":21862770,"source":{"system":"sec-edgar","filing":"0001140361-16-080886","document":"doc1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1082038/000114036116080886/doc1.xml","form_type":"4"}}]}