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Dr. Freund and Mr. Kaneko disclaim beneficial ownership of such securities, except to the extent of their pecuniary interest therein."}],"balance_after":2213425,"source":{"system":"sec-edgar","filing":"0001209191-18-055698","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1459839/000120919118055698/doc4.xml","form_type":"4"}},{"id":3798534,"issuer":{"id":5797,"kind":"organization","name":"SUTRO BIOPHARMA, INC.","symbol":"STRO"},"owners":[{"id":147193,"kind":"organization","name":"Skyline Venture Partners V LP","position":1,"cik":"0001419187","reported_name":"Skyline Venture Partners V LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":147194,"kind":"organization","name":"Skyline Venture Management V, LLC","position":2,"cik":"0001434887","reported_name":"Skyline Venture Management V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":38757,"kind":"person","name":"KANEKO YASUNORI","position":3,"cik":"0001277503","reported_name":"KANEKO YASUNORI","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series E Preferred Stock","published_at":"2018-10-03T12:36:57.000Z","date":"2018-10-01","kind":"exercise","acquired":false,"shares":18698578,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"By Skyline Venture Partners V, L.P."},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F4","text":"Each share of the issuer's Series E Preferred Stock automatically converted into 0.0275 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its IPO pursuant to the Registration Statement, and had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F4","text":"Each share of the issuer's Series E Preferred Stock automatically converted into 0.0275 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its IPO pursuant to the Registration Statement, and had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F4","text":"Each share of the issuer's Series E Preferred Stock automatically converted into 0.0275 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its IPO pursuant to the Registration Statement, and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"These securities are held of record by Skyline Venture Partners V, L.P. 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Mr. Freund is a director of the Issuer and, accordingly, files separate Section 16 reports."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":514211},"source":{"system":"sec-edgar","filing":"0001104659-18-060241","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1434887/000110465918060241/a4.xml","form_type":"4"}},{"id":3798533,"issuer":{"id":5797,"kind":"organization","name":"SUTRO BIOPHARMA, INC.","symbol":"STRO"},"owners":[{"id":147193,"kind":"organization","name":"Skyline Venture Partners V LP","position":1,"cik":"0001419187","reported_name":"Skyline Venture Partners V LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":147194,"kind":"organization","name":"Skyline Venture Management V, LLC","position":2,"cik":"0001434887","reported_name":"Skyline Venture Management V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":38757,"kind":"person","name":"KANEKO YASUNORI","position":3,"cik":"0001277503","reported_name":"KANEKO YASUNORI","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series D Preferred Stock","published_at":"2018-10-03T12:36:57.000Z","date":"2018-10-01","kind":"exercise","acquired":false,"shares":12846023,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"By Skyline Venture Partners V, L.P."},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F3","text":"Each share of the issuer's Series D Preferred Stock automatically converted into 0.0405 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its IPO pursuant to the Registration Statement, and had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"Each share of the issuer's Series D Preferred Stock automatically converted into 0.0405 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its IPO pursuant to the Registration Statement, and had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"Each share of the issuer's Series D Preferred Stock automatically converted into 0.0405 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its IPO pursuant to the Registration Statement, and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"These securities are held of record by Skyline Venture Partners V, L.P. (\"Skyline L.P.\"). Skyline Venture Management V, LLC (\"Skyline Management\") is the general partner of Skyline L.P. John G. Freund and Yasunori Kaneko, are the managing directors of Skyline Management, and each may be deemed to share voting and investment power over the securities held by Skyline L.P. and disclaims beneficial ownership over such securities except to the extent of their pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.  Mr. Freund is a director of the Issuer and, accordingly, files separate Section 16 reports."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":520264},"source":{"system":"sec-edgar","filing":"0001104659-18-060241","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1434887/000110465918060241/a4.xml","form_type":"4"}},{"id":3798532,"issuer":{"id":5797,"kind":"organization","name":"SUTRO BIOPHARMA, INC.","symbol":"STRO"},"owners":[{"id":147193,"kind":"organization","name":"Skyline Venture Partners V LP","position":1,"cik":"0001419187","reported_name":"Skyline Venture Partners V LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":147194,"kind":"organization","name":"Skyline Venture Management V, LLC","position":2,"cik":"0001434887","reported_name":"Skyline Venture Management V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":38757,"kind":"person","name":"KANEKO YASUNORI","position":3,"cik":"0001277503","reported_name":"KANEKO YASUNORI","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series C Preferred Stock","published_at":"2018-10-03T12:36:57.000Z","date":"2018-10-01","kind":"exercise","acquired":false,"shares":25015635,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"By Skyline Venture Partners V, L.P."},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each share of the issuer's Series C Preferred Stock automatically converted into 0.0370 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its firm commitment initial public offering (the \"IPO\") pursuant to a registration statement on Form S-1 (File No. 333-227103) under the Securities Act of 1933, as amended (the \"Registration Statement\"), and had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Each share of the issuer's Series C Preferred Stock automatically converted into 0.0370 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its firm commitment initial public offering (the \"IPO\") pursuant to a registration statement on Form S-1 (File No. 333-227103) under the Securities Act of 1933, as amended (the \"Registration Statement\"), and had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Each share of the issuer's Series C Preferred Stock automatically converted into 0.0370 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its firm commitment initial public offering (the \"IPO\") pursuant to a registration statement on Form S-1 (File No. 333-227103) under the Securities Act of 1933, as amended (the \"Registration Statement\"), and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"These securities are held of record by Skyline Venture Partners V, L.P. (\"Skyline L.P.\"). Skyline Venture Management V, LLC (\"Skyline Management\") is the general partner of Skyline L.P. John G. Freund and Yasunori Kaneko, are the managing directors of Skyline Management, and each may be deemed to share voting and investment power over the securities held by Skyline L.P. and disclaims beneficial ownership over such securities except to the extent of their pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.  Mr. Freund is a director of the Issuer and, accordingly, files separate Section 16 reports."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":925578},"source":{"system":"sec-edgar","filing":"0001104659-18-060241","document":"a4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1434887/000110465918060241/a4.xml","form_type":"4"}},{"id":3798531,"issuer":{"id":5797,"kind":"organization","name":"SUTRO BIOPHARMA, INC.","symbol":"STRO"},"owners":[{"id":147193,"kind":"organization","name":"Skyline Venture Partners V LP","position":1,"cik":"0001419187","reported_name":"Skyline Venture Partners V LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":147194,"kind":"organization","name":"Skyline Venture Management V, LLC","position":2,"cik":"0001434887","reported_name":"Skyline Venture Management V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":38757,"kind":"person","name":"KANEKO YASUNORI","position":3,"cik":"0001277503","reported_name":"KANEKO YASUNORI","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-10-03T12:36:57.000Z","date":"2018-10-01","kind":"exercise","acquired":true,"shares":514211,"ownership":{"direct":false,"nature":"By Skyline Venture Partners V, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F4","text":"Each share of the issuer's Series E Preferred Stock automatically converted into 0.0275 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its IPO pursuant to the Registration Statement, and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"These securities are held of record by Skyline Venture Partners V, L.P. (\"Skyline L.P.\"). Skyline Venture Management V, LLC (\"Skyline Management\") is the general partner of Skyline L.P. John G. Freund and Yasunori Kaneko, are the managing directors of Skyline Management, and each may be deemed to share voting and investment power over the securities held by Skyline L.P. and disclaims beneficial ownership over such securities except to the extent of their pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.  Mr. Freund is a director of the Issuer and, accordingly, files separate Section 16 reports."}],"balance_after":1960053,"source":{"system":"sec-edgar","filing":"0001104659-18-060241","document":"a4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1434887/000110465918060241/a4.xml","form_type":"4"}},{"id":3798530,"issuer":{"id":5797,"kind":"organization","name":"SUTRO BIOPHARMA, INC.","symbol":"STRO"},"owners":[{"id":147193,"kind":"organization","name":"Skyline Venture Partners V LP","position":1,"cik":"0001419187","reported_name":"Skyline Venture Partners V LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":147194,"kind":"organization","name":"Skyline Venture Management V, LLC","position":2,"cik":"0001434887","reported_name":"Skyline Venture Management V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":38757,"kind":"person","name":"KANEKO YASUNORI","position":3,"cik":"0001277503","reported_name":"KANEKO YASUNORI","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-10-03T12:36:57.000Z","date":"2018-10-01","kind":"exercise","acquired":true,"shares":520264,"ownership":{"direct":false,"nature":"By Skyline Venture Partners V, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"Each share of the issuer's Series D Preferred Stock automatically converted into 0.0405 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its IPO pursuant to the Registration Statement, and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"These securities are held of record by Skyline Venture Partners V, L.P. (\"Skyline L.P.\"). Skyline Venture Management V, LLC (\"Skyline Management\") is the general partner of Skyline L.P. John G. Freund and Yasunori Kaneko, are the managing directors of Skyline Management, and each may be deemed to share voting and investment power over the securities held by Skyline L.P. and disclaims beneficial ownership over such securities except to the extent of their pecuniary interest therein, and the inclusion of these securities in this report shall not be deemed an admission of beneficial ownership of the reported securities for purposes of Section 16 or for any other purposes.  Mr. Freund is a director of the Issuer and, accordingly, files separate Section 16 reports."}],"balance_after":1445842,"source":{"system":"sec-edgar","filing":"0001104659-18-060241","document":"a4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1434887/000110465918060241/a4.xml","form_type":"4"}},{"id":3798529,"issuer":{"id":5797,"kind":"organization","name":"SUTRO BIOPHARMA, INC.","symbol":"STRO"},"owners":[{"id":147193,"kind":"organization","name":"Skyline Venture Partners V LP","position":1,"cik":"0001419187","reported_name":"Skyline Venture Partners V LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":147194,"kind":"organization","name":"Skyline Venture Management V, LLC","position":2,"cik":"0001434887","reported_name":"Skyline Venture Management V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":38757,"kind":"person","name":"KANEKO YASUNORI","position":3,"cik":"0001277503","reported_name":"KANEKO YASUNORI","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-10-03T12:36:57.000Z","date":"2018-10-01","kind":"exercise","acquired":true,"shares":925578,"ownership":{"direct":false,"nature":"By Skyline Venture Partners V, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each share of the issuer's Series C Preferred Stock automatically converted into 0.0370 share of the issuer's Common Stock on October 1, 2018 in connection with the closing of the issuer's sale of its Common Stock in its firm commitment initial public offering (the \"IPO\") pursuant to a registration statement on Form S-1 (File No. 333-227103) under the Securities Act of 1933, as amended (the \"Registration Statement\"), and had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"These securities are held of record by Skyline Venture Partners V, L.P. 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Mr. Freund is a director of the Issuer and, accordingly, files separate Section 16 reports."}],"balance_after":925578,"source":{"system":"sec-edgar","filing":"0001104659-18-060241","document":"a4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1434887/000110465918060241/a4.xml","form_type":"4"}},{"id":4139163,"issuer":{"id":5169,"kind":"organization","name":"COLLEGIUM PHARMACEUTICAL, INC"},"owners":[{"id":147193,"kind":"organization","name":"Skyline Venture Partners V LP","position":1,"cik":"0001419187","reported_name":"Skyline Venture Partners V LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":147194,"kind":"organization","name":"Skyline Venture Management V, LLC","position":2,"cik":"0001434887","reported_name":"Skyline Venture Management V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-12-07T19:03:10.000Z","date":"2017-12-05","kind":"other","acquired":false,"shares":800000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Represents a pro rata in-kind distribution of the shares by Skyline Venture Partners V, L.P. without consideration to its limited and general partners."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"The shares are held by Skyline Venture Partners V, L.P. The general partner of Skyline Venture Partners V, L.P. is Skyline Venture Management V, LLC. John G. Freund and Yasunori Kaneko are managers of Skyline Venture Management V, LLC. These individuals share voting and investment power over the shares held by Skyline Venture Management, LLC and disclaim beneficial ownership of all the shares held by Skyline Venture Partners V, L.P. except to the extent of their proportionate pecuniary interest therein. Dr. Freund is a director of the Issuer and, accordingly, files separate Section 16 reports."}],"balance_after":2149916,"source":{"system":"sec-edgar","filing":"0001192482-17-000302","document":"edgar.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1434887/000119248217000302/edgar.xml","form_type":"4"}}]}