{"transactions":[{"id":2991118,"issuer":{"id":4765,"kind":"organization","name":"Oric Pharmaceuticals, Inc.","symbol":"ORIC"},"owners":[{"id":145515,"kind":"organization","name":"Topspin Fund L.P.","position":1,"cik":"0001615782","reported_name":"Topspin Fund L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145516,"kind":"organization","name":"Topspin Biotech Fund II, L.P.","position":2,"cik":"0001745827","reported_name":"Topspin Biotech Fund II, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145517,"kind":"organization","name":"LG Management, LLC","position":3,"cik":"0001685869","reported_name":"LG Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145518,"kind":"person","name":"GUTHART LEO","position":4,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-11-05T08:56:59.000Z","date":"2020-11-04","kind":"sale","acquired":false,"shares":2268750,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"On November 4, 2020, Topspin Biotech Fund II, L.P. distributed the 2,268,750 shares owned by it as follows: (1) 2,155,607 shares were distributed in-kind to its limited partners; and (2) 113,143 were distributed at the direction of LG Management, LLC, the general partner of Topspin Biotech Fund II, L.P., as follows: (a) 56,572 were distributed to Leo A. Guthart, the managing member of LG Management, LLC; and (b) an aggregate of 56,571 were distributed to two third-parties. The 113,143 shares distributed at the direction of LG Management, LLC were shares to which it was entitled in its capacity as general partner of Topspin Biotech Fund II, L.P."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"Consists of (1) 1,043,874 shares held of record by Topspin Fund, LP.; and (2) 56,572 shares owned by Leo A Guthart, individually. Each of Topspin Fund, LP and Leo A. Guthart disclaims beneficial ownership of the shares held of recod by the other."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"On November 4, 2020, Topspin Biotech Fund II, L.P. distributed the 2,268,750 shares owned by it as follows: (1) 2,155,607 shares were distributed in-kind to its limited partners; and (2) 113,143 were distributed at the direction of LG Management, LLC, the general partner of Topspin Biotech Fund II, L.P., as follows: (a) 56,572 were distributed to Leo A. Guthart, the managing member of LG Management, LLC; and (b) an aggregate of 56,571 were distributed to two third-parties. The 113,143 shares distributed at the direction of LG Management, LLC were shares to which it was entitled in its capacity as general partner of Topspin Biotech Fund II, L.P."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"1,043,874 of such shares are held directly by Topspin Fund L.P. LG Management, LLC, the general partner of Topspin Fund L.P., may be deemed to have voting and dispositive power with respect to the shares. Leo A. Guthart, the managing member of LG Management, LLC, may also be deemed to have voting and dispositive power with respect to the shares. Each of LG Management, LLC and Leo A. Guthart disclaims beneficial ownership of the shares, except to the extent of their respective indirect pecuniary interests in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Consists of (1) 1,043,874 shares held of record by Topspin Fund, LP.; and (2) 56,572 shares owned by Leo A Guthart, individually. Each of Topspin Fund, LP and Leo A. Guthart disclaims beneficial ownership of the shares held of recod by the other."}],"balance_after":1100446,"source":{"system":"sec-edgar","filing":"0001104659-20-121613","document":"tm2035065-2_4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1685869/000110465920121613/tm2035065-2_4.xml","form_type":"4"}},{"id":3130706,"issuer":{"id":62554,"kind":"organization","name":"RAPT Therapeutics, Inc.","symbol":"RAPT"},"owners":[{"id":145515,"kind":"organization","name":"Topspin Fund L.P.","position":1,"cik":"0001615782","reported_name":"Topspin Fund L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145516,"kind":"organization","name":"Topspin Biotech Fund II, L.P.","position":2,"cik":"0001745827","reported_name":"Topspin Biotech Fund II, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145517,"kind":"organization","name":"LG Management, LLC","position":3,"cik":"0001685869","reported_name":"LG Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145518,"kind":"person","name":"GUTHART LEO","position":4,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-05-29T12:21:53.000Z","date":"2020-05-26","kind":"sale","acquired":false,"shares":2056666,"ownership":{"direct":false,"nature":"Footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"On May 26, 2020, Topspin Biotech Fund II, L.P. distributed the 1,641,666 shares owned by it as follows: (1) 1,559,990 shares were distributed in-kind to its limited partners; and (2) 81,676 were distributed at the direction of LG Management, LLC, the general partner of Topspin Biotech Fund II, L.P., as follows: (a) 40,538 were distributed to Leo A. Guthart, the managing member of LG Management, LLC; and (b) an aggregate of 41,138 were distributed to two third-parties. The 81,676 shares distributed at the direction of LG Management, LLC were shares to which it was entitled in its capacity as general partner of Topspin Biotech Fund II, L.P."},{"field":"price","element":"transactionPricePerShare","label":"F3","text":"On May 26, 2020, Topspin Fund, L.P. distributed 415,000 shares owned by it to one of its limited partners."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F1","text":"Consists of (1) 518,705 shares held of record by Topspin Fund, LP.; and (2) 40,538 shares owned by Leo A Guthart, individually. Each of Topspin Fund, LP and Leo A. Guthart disclaims beneficial ownership of the shares held of recod by the other."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"On May 26, 2020, Topspin Biotech Fund II, L.P. distributed the 1,641,666 shares owned by it as follows: (1) 1,559,990 shares were distributed in-kind to its limited partners; and (2) 81,676 were distributed at the direction of LG Management, LLC, the general partner of Topspin Biotech Fund II, L.P., as follows: (a) 40,538 were distributed to Leo A. Guthart, the managing member of LG Management, LLC; and (b) an aggregate of 41,138 were distributed to two third-parties. The 81,676 shares distributed at the direction of LG Management, LLC were shares to which it was entitled in its capacity as general partner of Topspin Biotech Fund II, L.P."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"On May 26, 2020, Topspin Fund, L.P. distributed 415,000 shares owned by it to one of its limited partners."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"518,705 of such shares are held directly by Topspin Fund L.P. LG Management, LLC, the general partner of Topspin Fund L.P., may be deemed to have voting and dispositive power with respect to the shares. Leo A. Guthart, the managing member of LG Management, LLC, may also be deemed to have voting and dispositive power with respect to the shares. Each of LG Management, LLC and Leo A. 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The shares had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The securities are directly held by Topspin Biotech Fund L.P. LG Management, LLC, the general partner of Topspin Biotech Fund L.P., may be deemed to have voting and dispositive power with respect to the shares. Leo A. Guthart, the managing member of LG Management, LLC, may also be deemed to have voting and dispositive power with respect to the shares. Each of LG Management, LLC and Leo A. Guthart disclaims beneficial ownership of the shares, except to the extent of their respective indirect pecuniary interests in such shares."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":551306},"source":{"system":"sec-edgar","filing":"0000899243-18-020453","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1685869/000089924318020453/doc4.xml","form_type":"4"}},{"id":3862884,"issuer":{"id":137050,"kind":"organization","name":"CONSTELLATION PHARMACEUTICALS INC","symbol":"CNST"},"owners":[{"id":145515,"kind":"organization","name":"Topspin Fund L.P.","position":1,"cik":"0001615782","reported_name":"Topspin Fund L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145516,"kind":"organization","name":"Topspin Biotech Fund II, L.P.","position":2,"cik":"0001745827","reported_name":"Topspin Biotech Fund II, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145517,"kind":"organization","name":"LG Management, LLC","position":3,"cik":"0001685869","reported_name":"LG Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145518,"kind":"person","name":"GUTHART LEO","position":4,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series E Preferred Stock","published_at":"2018-07-23T20:07:04.000Z","date":"2018-07-23","kind":"exercise","acquired":false,"shares":6222222,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"By Funds"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The securities are directly held by Topspin Biotech Fund L.P. LG Management, LLC, the general partner of Topspin Biotech Fund L.P., may be deemed to have voting and dispositive power with respect to the shares. Leo A. Guthart, the managing member of LG Management, LLC, may also be deemed to have voting and dispositive power with respect to the shares. Each of LG Management, LLC and Leo A. Guthart disclaims beneficial ownership of the shares, except to the extent of their respective indirect pecuniary interests in such shares."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":726678},"source":{"system":"sec-edgar","filing":"0000899243-18-020453","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1685869/000089924318020453/doc4.xml","form_type":"4"}},{"id":3862883,"issuer":{"id":137050,"kind":"organization","name":"CONSTELLATION PHARMACEUTICALS INC","symbol":"CNST"},"owners":[{"id":145515,"kind":"organization","name":"Topspin Fund L.P.","position":1,"cik":"0001615782","reported_name":"Topspin Fund L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145516,"kind":"organization","name":"Topspin Biotech Fund II, L.P.","position":2,"cik":"0001745827","reported_name":"Topspin Biotech Fund II, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145517,"kind":"organization","name":"LG Management, LLC","position":3,"cik":"0001685869","reported_name":"LG Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145518,"kind":"person","name":"GUTHART LEO","position":4,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series F Preferred Stock","published_at":"2018-07-23T20:07:04.000Z","date":"2018-07-23","kind":"exercise","acquired":false,"shares":4500000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Topspin Fund L.P. LG Management, LLC, the general partner of Topspin Fund L.P., may be deemed to have voting and dispositive power with respect to the shares. Leo A. Guthart, the managing member of LG Management, LLC, may also be deemed to have voting and dispositive power with respect to the shares. Each of LG Management, LLC and Leo A. Guthart disclaims beneficial ownership of the shares, except to the extent of their respective indirect pecuniary interests in such shares."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":408758},"source":{"system":"sec-edgar","filing":"0000899243-18-020453","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1685869/000089924318020453/doc4.xml","form_type":"4"}},{"id":3862882,"issuer":{"id":137050,"kind":"organization","name":"CONSTELLATION PHARMACEUTICALS INC","symbol":"CNST"},"owners":[{"id":145515,"kind":"organization","name":"Topspin Fund L.P.","position":1,"cik":"0001615782","reported_name":"Topspin Fund L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145516,"kind":"organization","name":"Topspin Biotech Fund II, L.P.","position":2,"cik":"0001745827","reported_name":"Topspin Biotech Fund II, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145517,"kind":"organization","name":"LG Management, LLC","position":3,"cik":"0001685869","reported_name":"LG Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145518,"kind":"person","name":"GUTHART LEO","position":4,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series E-1 Preferred Stock","published_at":"2018-07-23T20:07:04.000Z","date":"2018-07-23","kind":"exercise","acquired":false,"shares":173408,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Topspin Fund L.P. LG Management, LLC, the general partner of Topspin Fund L.P., may be deemed to have voting and dispositive power with respect to the shares. Leo A. Guthart, the managing member of LG Management, LLC, may also be deemed to have voting and dispositive power with respect to the shares. Each of LG Management, LLC and Leo A. Guthart disclaims beneficial ownership of the shares, except to the extent of their respective indirect pecuniary interests in such shares."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":15750},"source":{"system":"sec-edgar","filing":"0000899243-18-020453","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1685869/000089924318020453/doc4.xml","form_type":"4"}},{"id":3862881,"issuer":{"id":137050,"kind":"organization","name":"CONSTELLATION PHARMACEUTICALS INC","symbol":"CNST"},"owners":[{"id":145515,"kind":"organization","name":"Topspin Fund L.P.","position":1,"cik":"0001615782","reported_name":"Topspin Fund L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145516,"kind":"organization","name":"Topspin Biotech Fund II, L.P.","position":2,"cik":"0001745827","reported_name":"Topspin Biotech Fund II, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145517,"kind":"organization","name":"LG Management, LLC","position":3,"cik":"0001685869","reported_name":"LG Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145518,"kind":"person","name":"GUTHART LEO","position":4,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series E Preferred Stock","published_at":"2018-07-23T20:07:04.000Z","date":"2018-07-23","kind":"exercise","acquired":false,"shares":177777,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Topspin Fund L.P. LG Management, LLC, the general partner of Topspin Fund L.P., may be deemed to have voting and dispositive power with respect to the shares. Leo A. Guthart, the managing member of LG Management, LLC, may also be deemed to have voting and dispositive power with respect to the shares. Each of LG Management, LLC and Leo A. Guthart disclaims beneficial ownership of the shares, except to the extent of their respective indirect pecuniary interests in such shares."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":20762},"source":{"system":"sec-edgar","filing":"0000899243-18-020453","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1685869/000089924318020453/doc4.xml","form_type":"4"}},{"id":3862880,"issuer":{"id":137050,"kind":"organization","name":"CONSTELLATION PHARMACEUTICALS INC","symbol":"CNST"},"owners":[{"id":145515,"kind":"organization","name":"Topspin Fund L.P.","position":1,"cik":"0001615782","reported_name":"Topspin Fund L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145516,"kind":"organization","name":"Topspin Biotech Fund II, L.P.","position":2,"cik":"0001745827","reported_name":"Topspin Biotech Fund II, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145517,"kind":"organization","name":"LG Management, LLC","position":3,"cik":"0001685869","reported_name":"LG Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145518,"kind":"person","name":"GUTHART LEO","position":4,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-07-23T20:07:04.000Z","date":"2018-07-23","kind":"exercise","acquired":true,"shares":54770,"ownership":{"direct":false,"nature":"By MSSB C/F Leo A. Guthart"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F4","text":"The securities are held directly by individual retirement accounts in the name of Leo A. Guthart and as a result Leo A Guthart may be deemed to be the beneficial owner of such shares. Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."}],"balance_after":54770,"source":{"system":"sec-edgar","filing":"0000899243-18-020453","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1685869/000089924318020453/doc4.xml","form_type":"4"}},{"id":3862879,"issuer":{"id":137050,"kind":"organization","name":"CONSTELLATION PHARMACEUTICALS INC","symbol":"CNST"},"owners":[{"id":145515,"kind":"organization","name":"Topspin Fund L.P.","position":1,"cik":"0001615782","reported_name":"Topspin Fund L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145516,"kind":"organization","name":"Topspin Biotech Fund II, L.P.","position":2,"cik":"0001745827","reported_name":"Topspin Biotech Fund II, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145517,"kind":"organization","name":"LG Management, LLC","position":3,"cik":"0001685869","reported_name":"LG Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145518,"kind":"person","name":"GUTHART LEO","position":4,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-07-23T20:07:04.000Z","date":"2018-07-23","kind":"exercise","acquired":true,"shares":1277984,"ownership":{"direct":false,"nature":"By Funds"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The securities are directly held by Topspin Biotech Fund L.P. LG Management, LLC, the general partner of Topspin Biotech Fund L.P., may be deemed to have voting and dispositive power with respect to the shares. Leo A. Guthart, the managing member of LG Management, LLC, may also be deemed to have voting and dispositive power with respect to the shares. Each of LG Management, LLC and Leo A. Guthart disclaims beneficial ownership of the shares, except to the extent of their respective indirect pecuniary interests in such shares."}],"balance_after":1277984,"source":{"system":"sec-edgar","filing":"0000899243-18-020453","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1685869/000089924318020453/doc4.xml","form_type":"4"}},{"id":3862878,"issuer":{"id":137050,"kind":"organization","name":"CONSTELLATION PHARMACEUTICALS INC","symbol":"CNST"},"owners":[{"id":145515,"kind":"organization","name":"Topspin Fund L.P.","position":1,"cik":"0001615782","reported_name":"Topspin Fund L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145516,"kind":"organization","name":"Topspin Biotech Fund II, L.P.","position":2,"cik":"0001745827","reported_name":"Topspin Biotech Fund II, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145517,"kind":"organization","name":"LG Management, LLC","position":3,"cik":"0001685869","reported_name":"LG Management, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":145518,"kind":"person","name":"GUTHART LEO","position":4,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-07-23T20:07:04.000Z","date":"2018-07-23","kind":"exercise","acquired":true,"shares":445270,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"On July 23, 2018, the Series E-1 and Series F Preferred Stock converted into Common Stock on a 11.009-for-one basis, and the Series E Preferred Stock converted into Common Stock on a 8.56256-for-one basis, upon the closing of the Issuer's initial public offering without payment of consideration. The Series E, Series E-1 and Series F Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial pubic offering. The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Topspin Fund L.P. LG Management, LLC, the general partner of Topspin Fund L.P., may be deemed to have voting and dispositive power with respect to the shares. Leo A. Guthart, the managing member of LG Management, LLC, may also be deemed to have voting and dispositive power with respect to the shares. Each of LG Management, LLC and Leo A. Guthart disclaims beneficial ownership of the shares, except to the extent of their respective indirect pecuniary interests in such shares."}],"balance_after":445270,"source":{"system":"sec-edgar","filing":"0000899243-18-020453","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1685869/000089924318020453/doc4.xml","form_type":"4"}},{"id":4102019,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2018-01-10T15:00:30.000Z","date":"2018-01-08","kind":"purchase","acquired":true,"shares":20000,"price":3.9,"value":78000.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The transaction reported herein was within a certain Individual Retirement Account in the name of Leo A. Guthart."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Taking into account the transaction reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 138,225 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 5,526,514 shares of the Issuer's Common Stock.  As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 5,526,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P.  However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 5,526,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":5664739,"source":{"system":"sec-edgar","filing":"0001144204-18-001673","document":"tv483057_4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420418001673/tv483057_4a.xml","form_type":"4/A","original_submission_date":"2017-05-22"}},{"id":4177419,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-10-31T18:45:47.000Z","date":"2017-10-31","kind":"gift","acquired":false,"shares":2500,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The transaction reported herein with a transaction date of October 31, 2017 was a bona fide gift made from an Individual Retirement Account in the name of Leo A. Guthart."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which, taking into account the transaction reported herein with a transaction date of October 27, 2017, is the direct beneficial owner of 5,526,514 shares of the Issuer's Common Stock. As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 5,526,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P. However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 5,526,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Taking into account the transaction reported herein with a transaction date of October 31, 2017, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 118,225 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":5644739,"source":{"system":"sec-edgar","filing":"0001144204-17-055242","document":"tv478067_4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417055242/tv478067_4a.xml","form_type":"4/A","original_submission_date":"2017-05-22"}},{"id":4177418,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-10-31T18:45:47.000Z","date":"2017-10-27","kind":"purchase","acquired":true,"shares":2439000,"price":4.1,"value":9999900.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The transaction reported herein with a transaction date of October 27, 2017 was a purchase made by Topspin Fund L.P. That purchase was made in connection with the Issuer's issuance and sale of 19,500,000 shares of the Issuer's Common Stock as disclosed in the Issuer's Form 8-K filed with the Commission on October 25, 2017."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which, taking into account the transaction reported herein with a transaction date of October 27, 2017, is the direct beneficial owner of 5,526,514 shares of the Issuer's Common Stock. As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 5,526,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P. However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 5,526,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Taking into account the transaction reported herein with a transaction date of October 31, 2017, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 118,225 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":5647239,"source":{"system":"sec-edgar","filing":"0001144204-17-055242","document":"tv478067_4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417055242/tv478067_4a.xml","form_type":"4/A","original_submission_date":"2017-05-22"}},{"id":4181187,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-10-24T15:14:50.000Z","date":"2017-10-24","kind":"purchase","acquired":true,"shares":10000,"price":4.3426,"value":43426.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The transactions reported herein were within a certain Individual Retirement Account in the name of Leo A. Guthart."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Taking into account the transactions reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 120,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock.  As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P.  However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3208239,"source":{"system":"sec-edgar","filing":"0001144204-17-053790","document":"tv477628_4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417053790/tv477628_4a.xml","form_type":"4/A","original_submission_date":"2017-05-22"}},{"id":4181186,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-10-24T15:14:50.000Z","date":"2017-10-24","kind":"purchase","acquired":true,"shares":10000,"price":4.3465,"value":43465.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The transactions reported herein were within a certain Individual Retirement Account in the name of Leo A. Guthart."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Taking into account the transactions reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 120,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock.  As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P.  However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3198239,"source":{"system":"sec-edgar","filing":"0001144204-17-053790","document":"tv477628_4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417053790/tv477628_4a.xml","form_type":"4/A","original_submission_date":"2017-05-22"}},{"id":4181185,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-10-24T15:14:50.000Z","date":"2017-10-24","kind":"purchase","acquired":true,"shares":20000,"price":4.35,"value":87000.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The transactions reported herein were within a certain Individual Retirement Account in the name of Leo A. Guthart."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Taking into account the transactions reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 120,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock.  As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P.  However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3188239,"source":{"system":"sec-edgar","filing":"0001144204-17-053790","document":"tv477628_4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417053790/tv477628_4a.xml","form_type":"4/A","original_submission_date":"2017-05-22"}},{"id":4181184,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-10-24T15:14:50.000Z","date":"2017-10-20","kind":"purchase","acquired":true,"shares":10000,"price":5.25,"value":52500.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The transactions reported herein were within a certain Individual Retirement Account in the name of Leo A. Guthart."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Taking into account the transactions reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 120,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock.  As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P.  However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3168239,"source":{"system":"sec-edgar","filing":"0001144204-17-053790","document":"tv477628_4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417053790/tv477628_4a.xml","form_type":"4/A","original_submission_date":"2017-05-22"}},{"id":4181183,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-10-24T15:14:50.000Z","date":"2017-10-20","kind":"purchase","acquired":true,"shares":10000,"price":5.26,"value":52600.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The transactions reported herein were within a certain Individual Retirement Account in the name of Leo A. Guthart."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Taking into account the transactions reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 120,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock.  As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P.  However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3158239,"source":{"system":"sec-edgar","filing":"0001144204-17-053790","document":"tv477628_4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417053790/tv477628_4a.xml","form_type":"4/A","original_submission_date":"2017-05-22"}},{"id":4182429,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-10-20T11:50:20.000Z","date":"2017-10-19","kind":"purchase","acquired":true,"shares":7656,"price":6,"value":45936.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The transactions reported herein were within a certain Individual Retirement Account in the name of Leo A. Guthart. Taking into account the transactions reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 60,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock. As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P. However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares. Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3148239,"source":{"system":"sec-edgar","filing":"0001144204-17-053397","document":"tv477405_4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417053397/tv477405_4a.xml","form_type":"4/A","original_submission_date":"2017-05-22"}},{"id":4182428,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-10-20T11:50:20.000Z","date":"2017-10-18","kind":"purchase","acquired":true,"shares":2344,"price":6.4,"value":15001.6,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The transactions reported herein were within a certain Individual Retirement Account in the name of Leo A. Guthart. Taking into account the transactions reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 60,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock. As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P. However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares. Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3140583,"source":{"system":"sec-edgar","filing":"0001144204-17-053397","document":"tv477405_4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417053397/tv477405_4a.xml","form_type":"4/A","original_submission_date":"2017-05-22"}},{"id":4203082,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-09-22T14:47:12.000Z","date":"2017-09-18","kind":"purchase","acquired":true,"shares":10000,"price":9.7,"value":97000.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"The transaction reported herein was within a certain Individual Retirement Account in the name of Leo A. Guthart. Taking into account the transaction reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 50,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock. As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P. However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares. Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3138239,"source":{"system":"sec-edgar","filing":"0001144204-17-049226","document":"v475674_4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417049226/v475674_4a.xml","form_type":"4/A","original_submission_date":"2017-05-22"}},{"id":4309949,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-05-22T19:40:57.000Z","date":"2017-05-10","kind":"purchase","acquired":true,"shares":5000,"price":6.14,"value":30700.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"All of the transactions reported herein were within a certain Individual Retirement Account in the name of Leo A. Guthart.\nTaking into account the transactions reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 40,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock.  As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P.  However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares.\nTable II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3128239,"source":{"system":"sec-edgar","filing":"0001144204-17-028951","document":"v467628_4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417028951/v467628_4.xml","form_type":"4"}},{"id":4309948,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-05-22T19:40:57.000Z","date":"2017-05-09","kind":"purchase","acquired":true,"shares":1000,"price":6.05,"value":6050.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"All of the transactions reported herein were within a certain Individual Retirement Account in the name of Leo A. Guthart.\nTaking into account the transactions reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 40,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock.  As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P.  However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares.\nTable II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3123239,"source":{"system":"sec-edgar","filing":"0001144204-17-028951","document":"v467628_4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417028951/v467628_4.xml","form_type":"4"}},{"id":4309947,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-05-22T19:40:57.000Z","date":"2017-05-09","kind":"purchase","acquired":true,"shares":6000,"price":6.06,"value":36360.0,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"All of the transactions reported herein were within a certain Individual Retirement Account in the name of Leo A. Guthart.\nTaking into account the transactions reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 40,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock.  As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P.  However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares.\nTable II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3122239,"source":{"system":"sec-edgar","filing":"0001144204-17-028951","document":"v467628_4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417028951/v467628_4.xml","form_type":"4"}},{"id":4309946,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-05-22T19:40:57.000Z","date":"2017-05-09","kind":"purchase","acquired":true,"shares":13270,"price":6.07,"value":80548.9,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"All of the transactions reported herein were within a certain Individual Retirement Account in the name of Leo A. Guthart.\nTaking into account the transactions reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 40,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock.  As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P.  However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares.\nTable II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3116239,"source":{"system":"sec-edgar","filing":"0001144204-17-028951","document":"v467628_4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417028951/v467628_4.xml","form_type":"4"}},{"id":4309945,"issuer":{"id":158527,"kind":"organization","name":"IMMUNE DESIGN CORP.","symbol":"IMDZ"},"owners":[{"id":145518,"kind":"person","name":"GUTHART LEO","position":1,"cik":"0001200183","reported_name":"GUTHART LEO","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2017-05-22T19:40:57.000Z","date":"2017-05-09","kind":"purchase","acquired":true,"shares":4730,"price":6.12,"value":28947.6,"ownership":{"direct":false,"nature":"See Note"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"All of the transactions reported herein were within a certain Individual Retirement Account in the name of Leo A. Guthart.\nTaking into account the transactions reported herein, Individual Retirement Accounts in the name of Leo A. Guthart are the direct beneficial owners of a total of 40,725 shares of the Issuer's Common Stock and, as a result, Leo A. Guthart may be deemed an indirect beneficial owner of such shares. However, Leo A. Guthart disclaims beneficial ownership of such shares, except to the extent of his indirect pecuniary interest in such shares."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Leo A. Guthart is the managing member of LG Management, LLC, which is the general partner of Topspin Fund L.P., which is the direct beneficial owner of 3,087,514 shares of the Issuer's Common Stock.  As a result, Leo A. Guthart may be deemed an indirect beneficial owner of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P.  However, Leo A. Guthart and LG Management, LLC disclaim beneficial ownership of the 3,087,514 shares of the Issuer's Common Stock directly beneficially owned by Topspin Fund L.P., except to the extent of their respective indirect pecuniary interests in such shares.\nTable II - Derivative Securities Acquired, Disposed of, or Beneficially Owned is intentionally omitted because there are no reportable transactions involving derivative securities."}],"balance_after":3102969,"source":{"system":"sec-edgar","filing":"0001144204-17-028951","document":"v467628_4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1437786/000114420417028951/v467628_4.xml","form_type":"4"}}]}