{"transactions":[{"id":2955276,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A-3 Convertible Preferred Stock","published_at":"2020-12-07T17:06:40.000Z","date":"2020-12-04","kind":"purchase","acquired":true,"shares":258707,"price":6.22,"value":1609157.54,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F3","text":"Each share of Class A-3 Convertible Preferred Stock, par value $0.001 per share (\"Class A-3 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of\nthe Issuer at a rate of 10 shares of Common Stock for each share of Class A-3 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-3 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-3 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated December 1, 2020 with a closing date of December 4, 2020."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"Each share of Class A-3 Convertible Preferred Stock, par value $0.001 per share (\"Class A-3 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of\nthe Issuer at a rate of 10 shares of Common Stock for each share of Class A-3 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-3 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-3 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F3","text":"Each share of Class A-3 Convertible Preferred Stock, par value $0.001 per share (\"Class A-3 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of\nthe Issuer at a rate of 10 shares of Common Stock for each share of Class A-3 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-3 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-3 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the\nsole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul\nWalker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in\nwhich the Indirect Reporting Persons have no pecuinary interest."}],"balance_after":258707,"derivative":{"exercise_date":"2020-12-04","underlying":"Common Stock","underlying_shares":2587070},"source":{"system":"sec-edgar","filing":"0001209191-20-061962","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120061962/doc4.xml","form_type":"4"}},{"id":2955275,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock Purchase Warrant (right to buy)","published_at":"2020-12-07T17:06:40.000Z","date":"2020-12-04","kind":"purchase","acquired":true,"shares":5239254,"price":0.125,"value":654906.75,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated December 1, 2020 with a closing date of December 4, 2020."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the\nsole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul\nWalker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in\nwhich the Indirect Reporting Persons have no pecuinary interest."}],"balance_after":5239254,"derivative":{"exercise_price":0.7464,"exercise_date":"2020-12-04","expiration_date":"2025-12-04","underlying":"Common Stock","underlying_shares":5239254},"source":{"system":"sec-edgar","filing":"0001209191-20-061962","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120061962/doc4.xml","form_type":"4"}},{"id":2955274,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-12-07T17:06:40.000Z","date":"2020-12-04","kind":"purchase","acquired":true,"shares":4398602,"price":0.622,"value":2735930.444,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated December 1, 2020 with a closing date of December 4, 2020."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the\nsole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\"). The individual managers of NEA 16 GP are Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, Scott D. Sandell, Peter W. Sonsini and Paul\nWalker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in\nwhich the Indirect Reporting Persons have no pecuinary interest."}],"balance_after":6451056,"source":{"system":"sec-edgar","filing":"0001209191-20-061962","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919120061962/doc4.xml","form_type":"4"}},{"id":3331378,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A-2 Convertible Preferred Stock","published_at":"2019-12-26T16:57:08.000Z","date":"2019-12-24","kind":"purchase","acquired":true,"shares":900900,"price":6.66,"value":5999994.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F4","text":"Each share of Class A-2 Convertible Preferred Stock, par value $0.001 per share (\"Class A-2 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of the Issuer at a rate of 10 shares of Common Stock for each share of Class A-2 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-2 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-2 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"kind","element":"transactionCoding","label":"F3","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated May 3, 2019 with a closing date of December 24, 2019."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F4","text":"Each share of Class A-2 Convertible Preferred Stock, par value $0.001 per share (\"Class A-2 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of the Issuer at a rate of 10 shares of Common Stock for each share of Class A-2 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-2 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-2 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F5","text":"Each share of Class A-1 Convertible Preferred Stock, par value $0.001 per share (\"Class A-1 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of the Issuer at a rate of 10 shares of Common Stock for each share of Class A-1 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-1 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-1 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\")."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":900900,"derivative":{"exercise_date":"2019-12-24","underlying":"Common Stock","underlying_shares":9009000},"source":{"system":"sec-edgar","filing":"0001209191-19-061963","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119061963/doc4.xml","form_type":"4"}},{"id":3331377,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock Purchase Warrant (Right to Buy)","published_at":"2019-12-26T16:57:08.000Z","date":"2019-12-24","kind":"purchase","acquired":true,"shares":9009000,"price":0.125,"value":1126125.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F3","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated May 3, 2019 with a closing date of December 24, 2019."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F1","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\")."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":9009000,"derivative":{"exercise_price":0.666,"exercise_date":"2019-12-24","expiration_date":"2024-12-24","underlying":"Common Stock","underlying_shares":9009000},"source":{"system":"sec-edgar","filing":"0001209191-19-061963","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119061963/doc4.xml","form_type":"4"}},{"id":3533690,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Class A-1 Convertible Preferred Stock","published_at":"2019-05-09T18:02:01.000Z","date":"2019-05-07","kind":"purchase","acquired":true,"shares":256700,"price":10.8,"value":2772360.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F4","text":"Each share of Class A-1 Convertible Preferred Stock, par value $0.001 per share (\"Class A-1 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of the Issuer at a rate of 10 shares of Common Stock for each share of Class A-1 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-1 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-1 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated May 3, 2019 with a closing date of May 7, 2019."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F4","text":"Each share of Class A-1 Convertible Preferred Stock, par value $0.001 per share (\"Class A-1 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of the Issuer at a rate of 10 shares of Common Stock for each share of Class A-1 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-1 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-1 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F4","text":"Each share of Class A-1 Convertible Preferred Stock, par value $0.001 per share (\"Class A-1 Preferred Stock\"), of the Issuer is convertible at any time into a number of shares of common stock, par value $0.001 (\"Common Stock\"), of the Issuer at a rate of 10 shares of Common Stock for each share of Class A-1 Preferred Stock, for no additional consideration, in each case subject to customary adjustments under the certificate of designations for the Class A-1 Preferred Stock (the \"Certificate of Designations\"). Unless converted pursuant to its terms, the Class A-1 Preferred Stock does not expire. The Certificate of Designations prohibits conversion to the extent that the holder, together with its affiliates, would beneficially own in excess of 9.99% of the number of shares of Common Stock outstanding immediately after giving effect to the conversion."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\")."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":256700,"derivative":{"exercise_date":"2019-05-07","underlying":"Common Stock","underlying_shares":2567000},"source":{"system":"sec-edgar","filing":"0001209191-19-028589","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119028589/doc4.xml","form_type":"4"}},{"id":3533689,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock Purchase Warrant (Right to Buy)","published_at":"2019-05-09T18:02:01.000Z","date":"2019-05-07","kind":"purchase","acquired":true,"shares":3703704,"price":0.125,"value":462963.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated May 3, 2019 with a closing date of May 7, 2019."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\")."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":3703704,"derivative":{"exercise_price":1.08,"exercise_date":"2019-05-07","expiration_date":"2024-05-07","underlying":"Common Stock","underlying_shares":3703704},"source":{"system":"sec-edgar","filing":"0001209191-19-028589","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119028589/doc4.xml","form_type":"4"}},{"id":3533688,"issuer":{"id":78034,"kind":"organization","name":"Regulus Therapeutics Inc.","symbol":"RGLS"},"owners":[{"id":141284,"kind":"organization","name":"Growth Equity Opportunities V, LLC","position":1,"cik":"0001706444","reported_name":"Growth Equity Opportunities V, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66498,"kind":"organization","name":"New Enterprise Associates 16, L.P.","position":2,"cik":"0001694560","reported_name":"New Enterprise Associates 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66499,"kind":"organization","name":"NEA Partners 16, L.P.","position":3,"cik":"0001712881","reported_name":"NEA Partners 16, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":66500,"kind":"organization","name":"NEA 16 GP, LLC","position":4,"cik":"0001712882","reported_name":"NEA 16 GP, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2019-05-09T18:02:01.000Z","date":"2019-05-07","kind":"purchase","acquired":true,"shares":1136704,"price":1.08,"value":1227640.32,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"Acquired from the Issuer pursuant to a Securities Purchase Agreement dated May 3, 2019 with a closing date of May 7, 2019."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by Growth Equity Opportunities Fund V, LLC (\"GEO V\") and indirectly held by New Enterprise Associates 16, L.P. (\"NEA 16\"), the sole member of GEO V, NEA Partners 16, L.P. (\"NEA Partners\"), the sole general partner of NEA 16, NEA 16 GP, LLC (\"NEA 16 GP\"), the sole general partner of NEA Partners 16, and the individual managers of NEA 16 GP (NEA 16, NEA Partners 16, NEA 16 GP and the individual managers of NEA 16 GP, together, the \"Indirect Reporting Persons\")."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The individual managers of NEA 16 GP are Peter J. Barris, Forest Baskett, Ali Behbahani, Carmen Chang, Anthony A. Florence, Jr., Mohamad Makhzoumi, Josh Makower, David M. Mott, Scott D. Sandell, Peter W. Sonsini and Paul Walker. The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended, or otherwise of such portion of the securities of the Issuer held by GEO V in which the Indirect Reporting Persons have no pecuniary interest."}],"balance_after":2052454,"source":{"system":"sec-edgar","filing":"0001209191-19-028589","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1712881/000120919119028589/doc4.xml","form_type":"4"}}]}