{"transactions":[{"id":2534313,"issuer":{"id":7122,"kind":"organization","name":"Xilio Therapeutics, Inc."},"owners":[{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":1,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series B Preferred Stock","published_at":"2021-10-26T17:30:00.000Z","date":"2021-10-26","kind":"exercise","acquired":false,"shares":359324,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each share of Series B Preferred Stock and Series C Preferred Stock automatically converted into 1 share of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 26, 2021. 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RiverVest Venture Partners IV, LLC is the general partner of RiverVest Partners IV."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The individual managers of RiverVest Ventures Partners IV, LLC are Jay Schmelter, John P. McKearn, Ph.D. and Niall O'Donnell. RiverVest Partners IV, RiverVest Venture Partners IV, LLC and each of the individual managers share voting and dispositive power with regard to the securities directly held by RiverVest Venture Fund IV, L.P."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":359324},"source":{"system":"sec-edgar","filing":"0000899243-21-041580","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1725443/000089924321041580/doc4.xml","form_type":"4"}},{"id":2534312,"issuer":{"id":7122,"kind":"organization","name":"Xilio Therapeutics, Inc."},"owners":[{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":1,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series B Preferred Stock","published_at":"2021-10-26T17:30:00.000Z","date":"2021-10-26","kind":"exercise","acquired":false,"shares":832120,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each share of Series B Preferred Stock and Series C Preferred Stock automatically converted into 1 share of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 26, 2021. The shares have no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Each share of Series B Preferred Stock and Series C Preferred Stock automatically converted into 1 share of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 26, 2021. The shares have no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Each share of Series B Preferred Stock and Series C Preferred Stock automatically converted into 1 share of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 26, 2021. The shares have no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The shares held by RiverVest Venture Fund IV, L.P. (\"RiverVest IV\") are indirectly held by RiverVest Venture Partners IV, L.P. (\"RiverVest Partners IV\"), which is the general partner of RiverVest IV. RiverVest Venture Partners IV, LLC is the general partner of RiverVest Partners IV."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The individual managers of RiverVest Ventures Partners IV, LLC are Jay Schmelter, John P. McKearn, Ph.D. and Niall O'Donnell. RiverVest Partners IV, RiverVest Venture Partners IV, LLC and each of the individual managers share voting and dispositive power with regard to the securities directly held by RiverVest Venture Fund IV, L.P."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":832120},"source":{"system":"sec-edgar","filing":"0000899243-21-041580","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1725443/000089924321041580/doc4.xml","form_type":"4"}},{"id":2534311,"issuer":{"id":7122,"kind":"organization","name":"Xilio Therapeutics, Inc."},"owners":[{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":1,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-10-26T17:30:00.000Z","date":"2021-10-26","kind":"purchase","acquired":true,"shares":250000,"price":16,"value":4000000.0,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F4","text":"RiverVest IV purchased the shares in the Issuer's initial public offering."},{"field":"shares","element":"transactionShares","label":"F4","text":"RiverVest IV purchased the shares in the Issuer's initial public offering."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The shares held by RiverVest Venture Fund IV, L.P. (\"RiverVest IV\") are indirectly held by RiverVest Venture Partners IV, L.P. (\"RiverVest Partners IV\"), which is the general partner of RiverVest IV. RiverVest Venture Partners IV, LLC is the general partner of RiverVest Partners IV."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The individual managers of RiverVest Ventures Partners IV, LLC are Jay Schmelter, John P. McKearn, Ph.D. and Niall O'Donnell. RiverVest Partners IV, RiverVest Venture Partners IV, LLC and each of the individual managers share voting and dispositive power with regard to the securities directly held by RiverVest Venture Fund IV, L.P."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"RiverVest IV purchased the shares in the Issuer's initial public offering."}],"balance_after":1441444,"source":{"system":"sec-edgar","filing":"0000899243-21-041580","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1725443/000089924321041580/doc4.xml","form_type":"4"}},{"id":2534310,"issuer":{"id":7122,"kind":"organization","name":"Xilio Therapeutics, Inc."},"owners":[{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":1,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-10-26T17:30:00.000Z","date":"2021-10-26","kind":"exercise","acquired":true,"shares":359324,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each share of Series B Preferred Stock and Series C Preferred Stock automatically converted into 1 share of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 26, 2021. The shares have no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The shares held by RiverVest Venture Fund IV, L.P. (\"RiverVest IV\") are indirectly held by RiverVest Venture Partners IV, L.P. (\"RiverVest Partners IV\"), which is the general partner of RiverVest IV. RiverVest Venture Partners IV, LLC is the general partner of RiverVest Partners IV."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The individual managers of RiverVest Ventures Partners IV, LLC are Jay Schmelter, John P. McKearn, Ph.D. and Niall O'Donnell. RiverVest Partners IV, RiverVest Venture Partners IV, LLC and each of the individual managers share voting and dispositive power with regard to the securities directly held by RiverVest Venture Fund IV, L.P."}],"balance_after":1191444,"source":{"system":"sec-edgar","filing":"0000899243-21-041580","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1725443/000089924321041580/doc4.xml","form_type":"4"}},{"id":2534309,"issuer":{"id":7122,"kind":"organization","name":"Xilio Therapeutics, Inc."},"owners":[{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":1,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-10-26T17:30:00.000Z","date":"2021-10-26","kind":"exercise","acquired":true,"shares":832120,"ownership":{"direct":false,"nature":"See Footnotes"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each share of Series B Preferred Stock and Series C Preferred Stock automatically converted into 1 share of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 26, 2021. The shares have no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The shares held by RiverVest Venture Fund IV, L.P. (\"RiverVest IV\") are indirectly held by RiverVest Venture Partners IV, L.P. (\"RiverVest Partners IV\"), which is the general partner of RiverVest IV. RiverVest Venture Partners IV, LLC is the general partner of RiverVest Partners IV."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The individual managers of RiverVest Ventures Partners IV, LLC are Jay Schmelter, John P. McKearn, Ph.D. and Niall O'Donnell. RiverVest Partners IV, RiverVest Venture Partners IV, LLC and each of the individual managers share voting and dispositive power with regard to the securities directly held by RiverVest Venture Fund IV, L.P."}],"balance_after":832120,"source":{"system":"sec-edgar","filing":"0000899243-21-041580","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1725443/000089924321041580/doc4.xml","form_type":"4"}},{"id":2750137,"issuer":{"id":6550,"kind":"organization","name":"OnKure Therapeutics, Inc.","symbol":"OKUR"},"owners":[{"id":140295,"kind":"organization","name":"RiverVest Venture Fund III, L.P.","position":1,"cik":"0001601559","reported_name":"RiverVest Venture Fund III, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140296,"kind":"organization","name":"RiverVest Venture Fund III (Ohio), L.P.","position":2,"cik":"0001636686","reported_name":"RiverVest Venture Fund III (Ohio), L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":3,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series B Preferred Stock","published_at":"2021-04-13T17:54:39.000Z","date":"2021-04-09","kind":"exercise","acquired":false,"shares":3710116,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 1 share of the Issuer's common stock for each 4.4748 shares of Preferred Stock upon the closing of the Issuer's initial public offering on April 9, 2021. The shares have no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 1 share of the Issuer's common stock for each 4.4748 shares of Preferred Stock upon the closing of the Issuer's initial public offering on April 9, 2021. The shares have no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 1 share of the Issuer's common stock for each 4.4748 shares of Preferred Stock upon the closing of the Issuer's initial public offering on April 9, 2021. The shares have no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Consists of shares held of record by RiverVest IV."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"The shares held by RiverVest IV are indirectly held by RiverVest Venture Partners IV, L.P., its general partner (\"RiverVest Partners IV\"). RiverVest Venture Partners IV, LLC is the general partner of RiverVest Partners IV. The individual managers of RiverVest Ventures Partners IV, LLC are Jay Schmelter, John P. McKearn, Ph.D. and Niall O'Donnell, a member of the Issuer's board of directors. RiverVest Partners IV, RiverVest Venture Partners IV, LLC and each of the individual managers share voting and dispositive power with regard to the Company's securities directly held by RiverVest IV."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":829113},"source":{"system":"sec-edgar","filing":"0000899243-21-015634","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1601559/000089924321015634/doc4.xml","form_type":"4"}},{"id":2750136,"issuer":{"id":6550,"kind":"organization","name":"OnKure Therapeutics, Inc.","symbol":"OKUR"},"owners":[{"id":140295,"kind":"organization","name":"RiverVest Venture Fund III, L.P.","position":1,"cik":"0001601559","reported_name":"RiverVest Venture Fund III, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140296,"kind":"organization","name":"RiverVest Venture Fund III (Ohio), L.P.","position":2,"cik":"0001636686","reported_name":"RiverVest Venture Fund III (Ohio), L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":3,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A Preferred Stock","published_at":"2021-04-13T17:54:39.000Z","date":"2021-04-09","kind":"exercise","acquired":false,"shares":4925711,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 1 share of the Issuer's common stock for each 4.4748 shares of Preferred Stock upon the closing of the Issuer's initial public offering on April 9, 2021. The shares have no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 1 share of the Issuer's common stock for each 4.4748 shares of Preferred Stock upon the closing of the Issuer's initial public offering on April 9, 2021. The shares have no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 1 share of the Issuer's common stock for each 4.4748 shares of Preferred Stock upon the closing of the Issuer's initial public offering on April 9, 2021. The shares have no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Consists of shares held of record by (i) RiverVest Venture Fund III, L.P. (\"RiverVest III\"), (ii) RiverVest Venture Fund III (Ohio), L.P. (\"RiverVest (Ohio) III\"), and (iii) RiverVest Venture Fund IV, L.P (\"RiverVest IV\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The shares held by RiverVest III are indirectly held by RiverVest Venture Partners III, L.P. (\"RiverVest Partners III\"), which is the general partner of RiverVest III. The shares held by RiverVest (Ohio) III are indirectly held by RiverVest Venture Partners III (Ohio), LLC (\"RiverVest Partners (Ohio) III\"), which is the general partner of RiverVest (Ohio) III. RiverVest Partners III is the sole member of RiverVest Partners (Ohio) III. RiverVest Venture Partners III, LLC is the general partner of RiverVest Partners III."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The individual managers of RiverVest Ventures Partners III, LLC are Thomas C. Melzer, Jay Schmelter and John P. McKearn, Ph.D. RiverVest Partners III, RiverVest Partners (Ohio) III, RiverVest Venture Partners III, LLC and each of the individual managers share voting and dispositive power with regard to the Issuer's securities directly held by RiverVest Venture Fund III, L.P. and RiverVest Venture Fund III (Ohio), L.P."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Consists of shares held of record by RiverVest IV."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"The shares held by RiverVest IV are indirectly held by RiverVest Venture Partners IV, L.P., its general partner (\"RiverVest Partners IV\"). RiverVest Venture Partners IV, LLC is the general partner of RiverVest Partners IV. The individual managers of RiverVest Ventures Partners IV, LLC are Jay Schmelter, John P. McKearn, Ph.D. and Niall O'Donnell, a member of the Issuer's board of directors. RiverVest Partners IV, RiverVest Venture Partners IV, LLC and each of the individual managers share voting and dispositive power with regard to the Company's securities directly held by RiverVest IV."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":1100765},"source":{"system":"sec-edgar","filing":"0000899243-21-015634","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1601559/000089924321015634/doc4.xml","form_type":"4"}},{"id":2750135,"issuer":{"id":6550,"kind":"organization","name":"OnKure Therapeutics, Inc.","symbol":"OKUR"},"owners":[{"id":140295,"kind":"organization","name":"RiverVest Venture Fund III, L.P.","position":1,"cik":"0001601559","reported_name":"RiverVest Venture Fund III, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140296,"kind":"organization","name":"RiverVest Venture Fund III (Ohio), L.P.","position":2,"cik":"0001636686","reported_name":"RiverVest Venture Fund III (Ohio), L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":3,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-04-13T17:54:39.000Z","date":"2021-04-09","kind":"purchase","acquired":true,"shares":200000,"price":15,"value":3000000.0,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F7","text":"RiverVest IV purchased the shares in the Issuer's initial public offering."},{"field":"shares","element":"transactionShares","label":"F7","text":"RiverVest IV purchased the shares in the Issuer's initial public offering."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F8","text":"The 2,409,220 shares consists of (i) 328,094 shares held of record by RiverVest III, (ii) 17,413 shares held of record by RiverVest (Ohio) III, and (iii) 2,063,713 shares held of record by RiverVest IV."}],"balance_after":2409220,"source":{"system":"sec-edgar","filing":"0000899243-21-015634","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1601559/000089924321015634/doc4.xml","form_type":"4"}},{"id":2750134,"issuer":{"id":6550,"kind":"organization","name":"OnKure Therapeutics, Inc.","symbol":"OKUR"},"owners":[{"id":140295,"kind":"organization","name":"RiverVest Venture Fund III, L.P.","position":1,"cik":"0001601559","reported_name":"RiverVest Venture Fund III, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140296,"kind":"organization","name":"RiverVest Venture Fund III (Ohio), L.P.","position":2,"cik":"0001636686","reported_name":"RiverVest Venture Fund III (Ohio), L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":3,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-04-13T17:54:39.000Z","date":"2021-04-09","kind":"exercise","acquired":true,"shares":829113,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 1 share of the Issuer's common stock for each 4.4748 shares of Preferred Stock upon the closing of the Issuer's initial public offering on April 9, 2021. The shares have no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Consists of shares held of record by RiverVest IV."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"The shares held by RiverVest IV are indirectly held by RiverVest Venture Partners IV, L.P., its general partner (\"RiverVest Partners IV\"). RiverVest Venture Partners IV, LLC is the general partner of RiverVest Partners IV. The individual managers of RiverVest Ventures Partners IV, LLC are Jay Schmelter, John P. McKearn, Ph.D. and Niall O'Donnell, a member of the Issuer's board of directors. RiverVest Partners IV, RiverVest Venture Partners IV, LLC and each of the individual managers share voting and dispositive power with regard to the Company's securities directly held by RiverVest IV."}],"balance_after":2209220,"source":{"system":"sec-edgar","filing":"0000899243-21-015634","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1601559/000089924321015634/doc4.xml","form_type":"4"}},{"id":2750133,"issuer":{"id":6550,"kind":"organization","name":"OnKure Therapeutics, Inc.","symbol":"OKUR"},"owners":[{"id":140295,"kind":"organization","name":"RiverVest Venture Fund III, L.P.","position":1,"cik":"0001601559","reported_name":"RiverVest Venture Fund III, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140296,"kind":"organization","name":"RiverVest Venture Fund III (Ohio), L.P.","position":2,"cik":"0001636686","reported_name":"RiverVest Venture Fund III (Ohio), L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":3,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-04-13T17:54:39.000Z","date":"2021-04-09","kind":"exercise","acquired":true,"shares":1100765,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 1 share of the Issuer's common stock for each 4.4748 shares of Preferred Stock upon the closing of the Issuer's initial public offering on April 9, 2021. The shares have no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Consists of shares held of record by (i) RiverVest Venture Fund III, L.P. (\"RiverVest III\"), (ii) RiverVest Venture Fund III (Ohio), L.P. (\"RiverVest (Ohio) III\"), and (iii) RiverVest Venture Fund IV, L.P (\"RiverVest IV\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The shares held by RiverVest III are indirectly held by RiverVest Venture Partners III, L.P. (\"RiverVest Partners III\"), which is the general partner of RiverVest III. The shares held by RiverVest (Ohio) III are indirectly held by RiverVest Venture Partners III (Ohio), LLC (\"RiverVest Partners (Ohio) III\"), which is the general partner of RiverVest (Ohio) III. RiverVest Partners III is the sole member of RiverVest Partners (Ohio) III. RiverVest Venture Partners III, LLC is the general partner of RiverVest Partners III."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The individual managers of RiverVest Ventures Partners III, LLC are Thomas C. Melzer, Jay Schmelter and John P. McKearn, Ph.D. RiverVest Partners III, RiverVest Partners (Ohio) III, RiverVest Venture Partners III, LLC and each of the individual managers share voting and dispositive power with regard to the Issuer's securities directly held by RiverVest Venture Fund III, L.P. and RiverVest Venture Fund III (Ohio), L.P."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Consists of shares held of record by RiverVest IV."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"The shares held by RiverVest IV are indirectly held by RiverVest Venture Partners IV, L.P., its general partner (\"RiverVest Partners IV\"). RiverVest Venture Partners IV, LLC is the general partner of RiverVest Partners IV. The individual managers of RiverVest Ventures Partners IV, LLC are Jay Schmelter, John P. McKearn, Ph.D. and Niall O'Donnell, a member of the Issuer's board of directors. RiverVest Partners IV, RiverVest Venture Partners IV, LLC and each of the individual managers share voting and dispositive power with regard to the Company's securities directly held by RiverVest IV."}],"balance_after":1380107,"source":{"system":"sec-edgar","filing":"0000899243-21-015634","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1601559/000089924321015634/doc4.xml","form_type":"4"}},{"id":3005330,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":140295,"kind":"organization","name":"RiverVest Venture Fund III, L.P.","position":1,"cik":"0001601559","reported_name":"RiverVest Venture Fund III, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140296,"kind":"organization","name":"RiverVest Venture Fund III (Ohio), L.P.","position":2,"cik":"0001636686","reported_name":"RiverVest Venture Fund III (Ohio), L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":3,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series B Preferred Stock","published_at":"2020-10-16T16:34:13.000Z","date":"2020-10-14","kind":"exercise","acquired":false,"shares":5416666,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 0.152881822351322 shares of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 14, 2020 (on an adjusted basis, after giving effect to the 1-for-6.541 reverse stock split of the common stock effected by the Issuer on October 2, 2020). The shares have no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 0.152881822351322 shares of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 14, 2020 (on an adjusted basis, after giving effect to the 1-for-6.541 reverse stock split of the common stock effected by the Issuer on October 2, 2020). The shares have no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 0.152881822351322 shares of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 14, 2020 (on an adjusted basis, after giving effect to the 1-for-6.541 reverse stock split of the common stock effected by the Issuer on October 2, 2020). The shares have no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The shares held by RiverVest III are indirectly held by RiverVest Venture Partners III, L.P. (\"RiverVest Partners III\"), which is the general partner of RiverVest III. The shares held by RiverVest (Ohio) III are indirectly held by RiverVest Venture Partners III (Ohio), LLC (\"RiverVest Partners (Ohio) III\"), which is the general partner of RiverVest (Ohio) III. RiverVest Partners III is the sole member of RiverVest Partners (Ohio) III. RiverVest Venture Partners III, LLC is the general partner of RiverVest Partners III."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The individual managers of RiverVest Ventures Partners III, LLC are Thomas C. Melzer, Jay Schmelter and John P. McKearn, Ph.D. RiverVest Partners III, RiverVest Partners (Ohio) III, RiverVest Venture Partners III, LLC and each of the individual managers share voting and dispositive power with regard to the Issuer's securities directly held by RiverVest Venture Fund III, L.P. and RiverVest Venture Fund III (Ohio), L.P."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Consists of (i) shares held of record by RiverVest III, (ii) RiverVest (Ohio) III, and (iii) RiverVest Venture Fund IV, L.P. (\"RiverVest IV\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"The shares held by RiverVest IV are indirectly held by RiverVest Venture Partners IV, L.P., its general partner (\"RiverVest Partners IV\"). RiverVest Venture Partners IV, LLC is the general partner of RiverVest Partners IV. The individual managers of RiverVest Ventures Partners IV, LLC are Jay Schmelter, John P. McKearn, Ph.D. and Niall O'Donnell, a member of the Issuer's board of directors. RiverVest Partners IV, RiverVest Venture Partners IV, LLC and each of the individual managers share voting and dispositive power with regard to the Company's securities directly held by RiverVest IV."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":828109},"source":{"system":"sec-edgar","filing":"0000899243-20-028479","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000089924320028479/doc4.xml","form_type":"4"}},{"id":3005329,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":140295,"kind":"organization","name":"RiverVest Venture Fund III, L.P.","position":1,"cik":"0001601559","reported_name":"RiverVest Venture Fund III, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140296,"kind":"organization","name":"RiverVest Venture Fund III (Ohio), L.P.","position":2,"cik":"0001636686","reported_name":"RiverVest Venture Fund III (Ohio), L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":3,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A Preferred Stock","published_at":"2020-10-16T16:34:13.000Z","date":"2020-10-14","kind":"exercise","acquired":false,"shares":7000000,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 0.152881822351322 shares of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 14, 2020 (on an adjusted basis, after giving effect to the 1-for-6.541 reverse stock split of the common stock effected by the Issuer on October 2, 2020). The shares have no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 0.152881822351322 shares of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 14, 2020 (on an adjusted basis, after giving effect to the 1-for-6.541 reverse stock split of the common stock effected by the Issuer on October 2, 2020). The shares have no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 0.152881822351322 shares of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 14, 2020 (on an adjusted basis, after giving effect to the 1-for-6.541 reverse stock split of the common stock effected by the Issuer on October 2, 2020). The shares have no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Consists of (i) shares held of record by RiverVest Venture Fund III, L.P. (\"RiverVest III\"), and (ii) RiverVest Venture Fund III (Ohio), L.P. (\"RiverVest (Ohio) III\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The shares held by RiverVest III are indirectly held by RiverVest Venture Partners III, L.P. (\"RiverVest Partners III\"), which is the general partner of RiverVest III. The shares held by RiverVest (Ohio) III are indirectly held by RiverVest Venture Partners III (Ohio), LLC (\"RiverVest Partners (Ohio) III\"), which is the general partner of RiverVest (Ohio) III. RiverVest Partners III is the sole member of RiverVest Partners (Ohio) III. RiverVest Venture Partners III, LLC is the general partner of RiverVest Partners III."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The individual managers of RiverVest Ventures Partners III, LLC are Thomas C. Melzer, Jay Schmelter and John P. McKearn, Ph.D. RiverVest Partners III, RiverVest Partners (Ohio) III, RiverVest Venture Partners III, LLC and each of the individual managers share voting and dispositive power with regard to the Issuer's securities directly held by RiverVest Venture Fund III, L.P. and RiverVest Venture Fund III (Ohio), L.P."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":1070172},"source":{"system":"sec-edgar","filing":"0000899243-20-028479","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000089924320028479/doc4.xml","form_type":"4"}},{"id":3005328,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":140295,"kind":"organization","name":"RiverVest Venture Fund III, L.P.","position":1,"cik":"0001601559","reported_name":"RiverVest Venture Fund III, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140296,"kind":"organization","name":"RiverVest Venture Fund III (Ohio), L.P.","position":2,"cik":"0001636686","reported_name":"RiverVest Venture Fund III (Ohio), L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":3,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-10-16T16:34:13.000Z","date":"2020-10-14","kind":"purchase","acquired":true,"shares":250000,"price":15,"value":3750000.0,"ownership":{"direct":false,"nature":"See footnote"},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F7","text":"RiverVest IV purchased the shares in the Issuer's initial public offering."},{"field":"shares","element":"transactionShares","label":"F7","text":"RiverVest IV purchased the shares in the Issuer's initial public offering."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F8","text":"The 2,148,281 shares consists of (i) 1,379,177 shares held of record by RiverVest III, (ii) 73,199 shares held of record by RiverVest (Ohio) III, and (iii) 445,905 shares held of record by RiverVest IV."}],"balance_after":2148281,"source":{"system":"sec-edgar","filing":"0000899243-20-028479","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000089924320028479/doc4.xml","form_type":"4"}},{"id":3005327,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":140295,"kind":"organization","name":"RiverVest Venture Fund III, L.P.","position":1,"cik":"0001601559","reported_name":"RiverVest Venture Fund III, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140296,"kind":"organization","name":"RiverVest Venture Fund III (Ohio), L.P.","position":2,"cik":"0001636686","reported_name":"RiverVest Venture Fund III (Ohio), L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":3,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-10-16T16:34:13.000Z","date":"2020-10-14","kind":"exercise","acquired":true,"shares":828109,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 0.152881822351322 shares of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 14, 2020 (on an adjusted basis, after giving effect to the 1-for-6.541 reverse stock split of the common stock effected by the Issuer on October 2, 2020). The shares have no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The shares held by RiverVest III are indirectly held by RiverVest Venture Partners III, L.P. (\"RiverVest Partners III\"), which is the general partner of RiverVest III. The shares held by RiverVest (Ohio) III are indirectly held by RiverVest Venture Partners III (Ohio), LLC (\"RiverVest Partners (Ohio) III\"), which is the general partner of RiverVest (Ohio) III. RiverVest Partners III is the sole member of RiverVest Partners (Ohio) III. RiverVest Venture Partners III, LLC is the general partner of RiverVest Partners III."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The individual managers of RiverVest Ventures Partners III, LLC are Thomas C. Melzer, Jay Schmelter and John P. McKearn, Ph.D. RiverVest Partners III, RiverVest Partners (Ohio) III, RiverVest Venture Partners III, LLC and each of the individual managers share voting and dispositive power with regard to the Issuer's securities directly held by RiverVest Venture Fund III, L.P. and RiverVest Venture Fund III (Ohio), L.P."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Consists of (i) shares held of record by RiverVest III, (ii) RiverVest (Ohio) III, and (iii) RiverVest Venture Fund IV, L.P. (\"RiverVest IV\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"The shares held by RiverVest IV are indirectly held by RiverVest Venture Partners IV, L.P., its general partner (\"RiverVest Partners IV\"). RiverVest Venture Partners IV, LLC is the general partner of RiverVest Partners IV. The individual managers of RiverVest Ventures Partners IV, LLC are Jay Schmelter, John P. McKearn, Ph.D. and Niall O'Donnell, a member of the Issuer's board of directors. RiverVest Partners IV, RiverVest Venture Partners IV, LLC and each of the individual managers share voting and dispositive power with regard to the Company's securities directly held by RiverVest IV."}],"balance_after":1898281,"source":{"system":"sec-edgar","filing":"0000899243-20-028479","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000089924320028479/doc4.xml","form_type":"4"}},{"id":3005326,"issuer":{"id":6471,"kind":"organization","name":"SPRUCE BIOSCIENCES, INC."},"owners":[{"id":140295,"kind":"organization","name":"RiverVest Venture Fund III, L.P.","position":1,"cik":"0001601559","reported_name":"RiverVest Venture Fund III, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":140296,"kind":"organization","name":"RiverVest Venture Fund III (Ohio), L.P.","position":2,"cik":"0001636686","reported_name":"RiverVest Venture Fund III (Ohio), L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":134210,"kind":"organization","name":"RiverVest Venture Fund IV, L.P.","position":3,"cik":"0001725443","reported_name":"RiverVest Venture Fund IV, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2020-10-16T16:34:13.000Z","date":"2020-10-14","kind":"exercise","acquired":true,"shares":1070172,"ownership":{"direct":false,"nature":"See footnotes"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each share of Series A Preferred Stock and Series B Preferred Stock automatically converted into 0.152881822351322 shares of the Issuer's common stock upon the closing of the Issuer's initial public offering on October 14, 2020 (on an adjusted basis, after giving effect to the 1-for-6.541 reverse stock split of the common stock effected by the Issuer on October 2, 2020). The shares have no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Consists of (i) shares held of record by RiverVest Venture Fund III, L.P. (\"RiverVest III\"), and (ii) RiverVest Venture Fund III (Ohio), L.P. (\"RiverVest (Ohio) III\")."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The shares held by RiverVest III are indirectly held by RiverVest Venture Partners III, L.P. (\"RiverVest Partners III\"), which is the general partner of RiverVest III. The shares held by RiverVest (Ohio) III are indirectly held by RiverVest Venture Partners III (Ohio), LLC (\"RiverVest Partners (Ohio) III\"), which is the general partner of RiverVest (Ohio) III. RiverVest Partners III is the sole member of RiverVest Partners (Ohio) III. RiverVest Venture Partners III, LLC is the general partner of RiverVest Partners III."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The individual managers of RiverVest Ventures Partners III, LLC are Thomas C. Melzer, Jay Schmelter and John P. McKearn, Ph.D. RiverVest Partners III, RiverVest Partners (Ohio) III, RiverVest Venture Partners III, LLC and each of the individual managers share voting and dispositive power with regard to the Issuer's securities directly held by RiverVest Venture Fund III, L.P. and RiverVest Venture Fund III (Ohio), L.P."}],"balance_after":1070172,"source":{"system":"sec-edgar","filing":"0000899243-20-028479","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1683553/000089924320028479/doc4.xml","form_type":"4"}}]}