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These shares were sold in multiple transactions at prices ranging from $15.05 to $15.22, inclusive. The reporting person undertakes to provide to Cue Biopharma, Inc., any security holder of Cue Biopharma, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in this footnote (3) to this Form 4."}],"balance_after":2000,"source":{"system":"sec-edgar","filing":"0001209191-21-021293","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1571862/000120919121021293/doc4.xml","form_type":"4"}},{"id":2781078,"issuer":{"id":6301,"kind":"organization","name":"Cue Biopharma, Inc.","symbol":"CUE"},"owners":[{"id":128673,"kind":"person","name":"Pienta Kenneth","position":1,"cik":"0001571862","reported_name":"Pienta Kenneth","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Medical Officer"}}],"security":"Common Stock","published_at":"2021-03-17T16:00:26.000Z","date":"2021-03-16","kind":"exercise","acquired":true,"shares":439,"price":5,"value":2195.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 20, 2020."}],"balance_after":2439,"source":{"system":"sec-edgar","filing":"0001209191-21-021293","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1571862/000120919121021293/doc4.xml","form_type":"4"}},{"id":2781077,"issuer":{"id":6301,"kind":"organization","name":"Cue Biopharma, Inc.","symbol":"CUE"},"owners":[{"id":128673,"kind":"person","name":"Pienta Kenneth","position":1,"cik":"0001571862","reported_name":"Pienta Kenneth","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Medical Officer"}}],"security":"Common Stock","published_at":"2021-03-17T16:00:26.000Z","date":"2021-03-15","kind":"sale","acquired":false,"shares":13000,"price":15.0976,"value":196268.8,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 20, 2020."},{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in Column 4 is a weighted average price. 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The reporting person undertakes to provide to Cue Biopharma, Inc., any security holder of Cue Biopharma, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in this footnote (2) to this Form 4."}],"balance_after":2000,"source":{"system":"sec-edgar","filing":"0001209191-21-021293","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1571862/000120919121021293/doc4.xml","form_type":"4"}},{"id":2781076,"issuer":{"id":6301,"kind":"organization","name":"Cue Biopharma, Inc.","symbol":"CUE"},"owners":[{"id":128673,"kind":"person","name":"Pienta Kenneth","position":1,"cik":"0001571862","reported_name":"Pienta Kenneth","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Medical Officer"}}],"security":"Common 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These shares were sold in multiple transactions at prices ranging from $15.06 to $15.60, inclusive. The reporting person undertakes to provide to Cue Biopharma, Inc., any security holder of Cue Biopharma, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in this footnote (2) to this Form 4."}],"balance_after":2000,"source":{"system":"sec-edgar","filing":"0000899243-21-007232","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1571862/000089924321007232/doc4.xml","form_type":"4"}},{"id":2848888,"issuer":{"id":6301,"kind":"organization","name":"Cue Biopharma, Inc.","symbol":"CUE"},"owners":[{"id":128673,"kind":"person","name":"Pienta Kenneth","position":1,"cik":"0001571862","reported_name":"Pienta Kenneth","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Medical Officer"}}],"security":"Common Stock","published_at":"2021-02-18T20:44:22.000Z","date":"2021-02-16","kind":"exercise","acquired":true,"shares":16000,"price":2.86,"value":45760.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 20, 2020."}],"balance_after":18000,"source":{"system":"sec-edgar","filing":"0000899243-21-007232","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1571862/000089924321007232/doc4.xml","form_type":"4"}},{"id":2848882,"issuer":{"id":6301,"kind":"organization","name":"Cue Biopharma, Inc.","symbol":"CUE"},"owners":[{"id":128673,"kind":"person","name":"Pienta Kenneth","position":1,"cik":"0001571862","reported_name":"Pienta Kenneth","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Medical Officer"}}],"security":"Stock Option (right to buy)","published_at":"2021-02-18T20:40:10.000Z","date":"2021-01-20","kind":"exercise","acquired":false,"shares":2720,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 20, 2020."},{"field":"shares","element":"transactionShares","label":"F2","text":"This option exercise was omitted from the reporting person's original Form 4."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F5","text":"The option, representing a right to purchase a total of 20,000 shares, became exercisable in full on November 16, 2017."}],"balance_after":17280,"derivative":{"exercise_price":2.86,"expiration_date":"2023-11-16","underlying":"Common Stock","underlying_shares":2720},"source":{"system":"sec-edgar","filing":"0000899243-21-007230","document":"doc4a.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1571862/000089924321007230/doc4a.xml","form_type":"4/A","original_submission_date":"2021-01-22"}},{"id":2848881,"issuer":{"id":6301,"kind":"organization","name":"Cue Biopharma, Inc.","symbol":"CUE"},"owners":[{"id":128673,"kind":"person","name":"Pienta Kenneth","position":1,"cik":"0001571862","reported_name":"Pienta Kenneth","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Medical Officer"}}],"security":"Common Stock","published_at":"2021-02-18T20:40:10.000Z","date":"2021-01-20","kind":"sale","acquired":false,"shares":2720,"price":15.066,"value":40979.52,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 20, 2020."},{"field":"kind","element":"transactionCoding","label":"F3","text":"This transaction was incorrectly reported using Code \"P\" in the reporting person's original Form 4."},{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The price reported in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $15.02 to $15.26, inclusive. The reporting person undertakes to provide to Cue Biopharma, Inc., any security holder of Cue Biopharma, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in this footnote (4) to this Form 4."}],"balance_after":2000,"source":{"system":"sec-edgar","filing":"0000899243-21-007230","document":"doc4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1571862/000089924321007230/doc4a.xml","form_type":"4/A","original_submission_date":"2021-01-22"}},{"id":2848880,"issuer":{"id":6301,"kind":"organization","name":"Cue Biopharma, Inc.","symbol":"CUE"},"owners":[{"id":128673,"kind":"person","name":"Pienta Kenneth","position":1,"cik":"0001571862","reported_name":"Pienta Kenneth","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Medical Officer"}}],"security":"Common Stock","published_at":"2021-02-18T20:40:10.000Z","date":"2021-01-20","kind":"exercise","acquired":true,"shares":2720,"price":2.86,"value":7779.2,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The transactions reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on August 20, 2020."},{"field":"shares","element":"transactionShares","label":"F2","text":"This option exercise was omitted from the reporting person's original Form 4."}],"balance_after":4720,"source":{"system":"sec-edgar","filing":"0000899243-21-007230","document":"doc4a.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1571862/000089924321007230/doc4a.xml","form_type":"4/A","original_submission_date":"2021-01-22"}},{"id":2862439,"issuer":{"id":6301,"kind":"organization","name":"Cue Biopharma, Inc.","symbol":"CUE"},"owners":[{"id":128673,"kind":"person","name":"Pienta Kenneth","position":1,"cik":"0001571862","reported_name":"Pienta Kenneth","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Medical Officer"}}],"security":"Stock Option (right to buy)","published_at":"2021-02-12T17:52:13.000Z","date":"2021-02-10","kind":"grant","acquired":true,"shares":50000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This stock option grant becomes exercisable in eight equal semi-annual installments beginning August 10, 2021."}],"balance_after":50000,"derivative":{"exercise_price":15.55,"expiration_date":"2031-02-09","underlying":"Common Stock","underlying_shares":50000},"source":{"system":"sec-edgar","filing":"0000899243-21-006362","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1571862/000089924321006362/doc4.xml","form_type":"4"}},{"id":2898802,"issuer":{"id":6301,"kind":"organization","name":"Cue Biopharma, Inc.","symbol":"CUE"},"owners":[{"id":128673,"kind":"person","name":"Pienta Kenneth","position":1,"cik":"0001571862","reported_name":"Pienta Kenneth","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Medical Officer"}}],"security":"Common Stock","published_at":"2021-01-22T16:33:13.000Z","date":"2021-01-20","kind":"purchase","acquired":true,"shares":2720,"price":15.066,"value":40979.52,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $15.02 to $15.26, inclusive. The reporting person undertakes to provide to Cue Biopharma, Inc., any security holder of Cue Biopharma, Inc., or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares purchased at each separate price within the ranges set forth in this footnote (1) to this Form 4."}],"balance_after":4720,"source":{"system":"sec-edgar","filing":"0000899243-21-002947","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1571862/000089924321002947/doc4.xml","form_type":"4"}},{"id":3193992,"issuer":{"id":6301,"kind":"organization","name":"Cue Biopharma, Inc.","symbol":"CUE"},"owners":[{"id":128673,"kind":"person","name":"Pienta Kenneth","position":1,"cik":"0001571862","reported_name":"Pienta Kenneth","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Medical Officer"}}],"security":"Stock Option (right to buy)","published_at":"2020-03-26T16:11:46.000Z","date":"2020-03-24","kind":"grant","acquired":true,"shares":100000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This stock option grant becomes exercisable in eight equal semi-annual installments beginning September 24, 2020."}],"balance_after":100000,"derivative":{"exercise_price":14,"expiration_date":"2030-03-24","underlying":"Common Stock","underlying_shares":100000},"source":{"system":"sec-edgar","filing":"0001209191-20-021239","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1571862/000120919120021239/doc4.xml","form_type":"4"}},{"id":4094324,"issuer":{"id":6301,"kind":"organization","name":"Cue Biopharma, Inc.","symbol":"CUE"},"owners":[{"id":128673,"kind":"person","name":"Pienta Kenneth","position":1,"cik":"0001571862","reported_name":"Pienta Kenneth","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Medical Officer"}}],"security":"Common Stock","published_at":"2018-01-19T17:03:03.000Z","date":"2017-12-27","kind":"purchase","acquired":true,"shares":2000,"price":7.5,"value":15000.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"Reflects shares of the Issuer's common stock that were purchased in connection with the Issuer's initial public offering."}],"balance_after":2000,"source":{"system":"sec-edgar","filing":"0001209191-18-004591","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1571862/000120919118004591/doc4.xml","form_type":"4"}},{"id":4410256,"issuer":{"id":8401,"kind":"organization","name":"CURIS INC"},"owners":[{"id":128673,"kind":"person","name":"Pienta Kenneth","position":1,"cik":"0001571862","reported_name":"Pienta Kenneth","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Non-qualified stock option","published_at":"2017-03-02T21:56:26.000Z","date":"2017-02-28","kind":"grant","acquired":true,"shares":120000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Options granted under the 2010 Amended and Restated Stock Incentive Plan and 1/12th of the total shares will vest monthly beginning on January 1, 2017 until all of the shares underlying the award become vested on January 1, 2018, subject to the director's continued service with the Company."}],"balance_after":120000,"derivative":{"exercise_price":2.31,"expiration_date":"2027-02-27","underlying":"Common Stock","underlying_shares":120000},"source":{"system":"sec-edgar","filing":"0001209191-17-016742","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1108205/000120919117016742/doc4.xml","form_type":"4"}}]}