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Otello Stampacchia, Claudio Nessi and Anne-Mari Paster are all the shareholders and directors of Omega VI GP Manager and have shared voting and investment power over the shares held by Omega VI and, as a result, may each be deemed to beneficially own the reported securities. Each of such individuals disclaims beneficial ownership of the shares held by Omega VI."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"As of October 12, 2021 and after giving effect to the transactions reported above, Omega VI holds less than 10% of the outstanding shares of the Issuer's Common Stock."}],"balance_after":523979,"source":{"system":"sec-edgar","filing":"0000899243-21-040245","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1745020/000089924321040245/doc4.xml","form_type":"4"}},{"id":2863806,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":128201,"kind":"organization","name":"Omega Fund V, L.P.","position":1,"cik":"0001641354","reported_name":"Omega Fund V, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":128202,"kind":"organization","name":"Omega Fund V GP, L.P.","position":2,"cik":"0001641355","reported_name":"Omega Fund V GP, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":128203,"kind":"organization","name":"Omega Fund V GP Manager, Ltd.","position":3,"cik":"0001641348","reported_name":"Omega Fund V GP Manager, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":36727,"kind":"person","name":"Stampacchia Otello","position":4,"cik":"0001361712","reported_name":"Stampacchia Otello","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":108425,"kind":"person","name":"Nessi Claudio","position":5,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":108426,"kind":"person","name":"Paster Anne-Mari","position":6,"cik":"0001652863","reported_name":"Paster Anne-Mari","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":76396,"kind":"person","name":"DOIG MICHELLE","position":7,"cik":"0001832320","reported_name":"DOIG MICHELLE","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Series A Preferred Stock","published_at":"2021-02-12T22:59:03.000Z","date":"2021-02-10","kind":"exercise","acquired":false,"shares":8130097,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Received pursuant to the Agreement and Plan of Merger, dated as of October 20, 2020, by and among Panacea Acquisition Corp. (\"Panacea\") and Panacea Merger Subsidiary Corp., a direct, wholly-owned subsidiary of Panacea (\"Merger Sub\"), and Nuvation Bio Inc. (\"Legacy Nuvation\") pursuant to which, as a result of a merger between Legacy Nuvation and Merger Sub, Legacy Nuvation became a direct, wholly-owned subsidiary of Panacea, which subsequently changed its name to Nuvation Bio Inc. (the \"Issuer\").  The transactions contemplated by the Merger Agreement are referred to herein as the \"Business Combination.\""},{"field":"kind","element":"transactionCoding","label":"F5","text":"Each share of Series A Preferred Stock stock automatically converted into Class A Common Stock on a 1-for-1 basis immediately prior to the closing of the Business Combination and has no expiration date nor conversion price."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Received pursuant to the Agreement and Plan of Merger, dated as of October 20, 2020, by and among Panacea Acquisition Corp. (\"Panacea\") and Panacea Merger Subsidiary Corp., a direct, wholly-owned subsidiary of Panacea (\"Merger Sub\"), and Nuvation Bio Inc. (\"Legacy Nuvation\") pursuant to which, as a result of a merger between Legacy Nuvation and Merger Sub, Legacy Nuvation became a direct, wholly-owned subsidiary of Panacea, which subsequently changed its name to Nuvation Bio Inc. (the \"Issuer\").  The transactions contemplated by the Merger Agreement are referred to herein as the \"Business Combination.\""},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Received pursuant to the Agreement and Plan of Merger, dated as of October 20, 2020, by and among Panacea Acquisition Corp. (\"Panacea\") and Panacea Merger Subsidiary Corp., a direct, wholly-owned subsidiary of Panacea (\"Merger Sub\"), and Nuvation Bio Inc. (\"Legacy Nuvation\") pursuant to which, as a result of a merger between Legacy Nuvation and Merger Sub, Legacy Nuvation became a direct, wholly-owned subsidiary of Panacea, which subsequently changed its name to Nuvation Bio Inc. (the \"Issuer\").  The transactions contemplated by the Merger Agreement are referred to herein as the \"Business Combination.\""}],"balance_after":0,"derivative":{"underlying":"Class A Common Stock","underlying_shares":8130097},"source":{"system":"sec-edgar","filing":"0001209191-21-010367","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1811063/000120919121010367/doc4.xml","form_type":"4"}},{"id":2863805,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":128201,"kind":"organization","name":"Omega Fund V, L.P.","position":1,"cik":"0001641354","reported_name":"Omega Fund V, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":128202,"kind":"organization","name":"Omega Fund V GP, L.P.","position":2,"cik":"0001641355","reported_name":"Omega Fund V GP, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":128203,"kind":"organization","name":"Omega Fund V GP Manager, Ltd.","position":3,"cik":"0001641348","reported_name":"Omega Fund V GP Manager, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":36727,"kind":"person","name":"Stampacchia Otello","position":4,"cik":"0001361712","reported_name":"Stampacchia Otello","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":108425,"kind":"person","name":"Nessi Claudio","position":5,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":108426,"kind":"person","name":"Paster Anne-Mari","position":6,"cik":"0001652863","reported_name":"Paster Anne-Mari","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":76396,"kind":"person","name":"DOIG MICHELLE","position":7,"cik":"0001832320","reported_name":"DOIG MICHELLE","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Class A Common Stock","published_at":"2021-02-12T22:59:03.000Z","date":"2021-02-10","kind":"grant","acquired":true,"shares":500000,"price":10,"value":5000000.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F4","text":"On October 20, 2020, the Issuer entered into subscription agreements (the \"Subscription Agreements\") with certain investors (the \"PIPE Investors\") pursuant to which such investors agreed to purchase, immediately prior to the closing of the Business Combination, as defined herein, an aggregate of $476,550,000 of the Issuer's shares of Class A Common Stock at a price of $10.00 per share, or an aggregate of 47,655,000 shares of Class A Common Stock. The Reporting Person is among the PIPE Investors."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The reported securities are held directly by Omega Fund V, L.P. (\"Omega V\"). The reported securities may be deemed to be beneficially owned by each of Omega Fund V GP, L.P. (\"Omega V GP\"), as the general partner of Omega V, and Omega Fund V GP Manager, Ltd. (\"Omega V GP Manager\"), as the general partner of Omega V GP. Otello Stampacchia, Anne-Mari Paster and Claudio Nessi (the \"Omega Directors\") are all the shareholders and directors of Omega V GP Manager and have shared voting and investment power over the shares held by Omega V. Michelle Doig is a partner of Omega V and shares voting and investment power over the shares held by Omega V.  Each of Omega V GP, Omega Fund V GP Manager, the Omega Directors and Michelle Doig disclaims beneficial ownership of the securities reported herein, except to the extent of its or their pecuniary interest therein, if any."}],"balance_after":28212373,"source":{"system":"sec-edgar","filing":"0001209191-21-010367","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1811063/000120919121010367/doc4.xml","form_type":"4"}},{"id":2863804,"issuer":{"id":4384,"kind":"organization","name":"Nuvation Bio Inc."},"owners":[{"id":128201,"kind":"organization","name":"Omega Fund V, L.P.","position":1,"cik":"0001641354","reported_name":"Omega Fund V, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":128202,"kind":"organization","name":"Omega Fund V GP, L.P.","position":2,"cik":"0001641355","reported_name":"Omega Fund V GP, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":128203,"kind":"organization","name":"Omega Fund V GP Manager, Ltd.","position":3,"cik":"0001641348","reported_name":"Omega Fund V GP Manager, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":36727,"kind":"person","name":"Stampacchia Otello","position":4,"cik":"0001361712","reported_name":"Stampacchia Otello","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":108425,"kind":"person","name":"Nessi Claudio","position":5,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":108426,"kind":"person","name":"Paster Anne-Mari","position":6,"cik":"0001652863","reported_name":"Paster Anne-Mari","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":76396,"kind":"person","name":"DOIG MICHELLE","position":7,"cik":"0001832320","reported_name":"DOIG MICHELLE","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Class A Common Stock","published_at":"2021-02-12T22:59:03.000Z","date":"2021-02-10","kind":"exercise","acquired":true,"shares":8130097,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Received pursuant to the Agreement and Plan of Merger, dated as of October 20, 2020, by and among Panacea Acquisition Corp. (\"Panacea\") and Panacea Merger Subsidiary Corp., a direct, wholly-owned subsidiary of Panacea (\"Merger Sub\"), and Nuvation Bio Inc. (\"Legacy Nuvation\") pursuant to which, as a result of a merger between Legacy Nuvation and Merger Sub, Legacy Nuvation became a direct, wholly-owned subsidiary of Panacea, which subsequently changed its name to Nuvation Bio Inc. (the \"Issuer\").  The transactions contemplated by the Merger Agreement are referred to herein as the \"Business Combination.\""},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 19,582,276 shares issued in connection with the conversion of shares of Class A Common Stock in the Business Combination, as defined herein."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F3","text":"The reported securities are held directly by Omega Fund V, L.P. (\"Omega V\"). The reported securities may be deemed to be beneficially owned by each of Omega Fund V GP, L.P. (\"Omega V GP\"), as the general partner of Omega V, and Omega Fund V GP Manager, Ltd. (\"Omega V GP Manager\"), as the general partner of Omega V GP. Otello Stampacchia, Anne-Mari Paster and Claudio Nessi (the \"Omega Directors\") are all the shareholders and directors of Omega V GP Manager and have shared voting and investment power over the shares held by Omega V. Michelle Doig is a partner of Omega V and shares voting and investment power over the shares held by Omega V.  Each of Omega V GP, Omega Fund V GP Manager, the Omega Directors and Michelle Doig disclaims beneficial ownership of the securities reported herein, except to the extent of its or their pecuniary interest therein, if any."}],"balance_after":27712373,"source":{"system":"sec-edgar","filing":"0001209191-21-010367","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1811063/000120919121010367/doc4.xml","form_type":"4"}},{"id":3005367,"issuer":{"id":78257,"kind":"organization","name":"Kronos Bio, Inc.","symbol":"KRON"},"owners":[{"id":128201,"kind":"organization","name":"Omega Fund V, L.P.","position":1,"cik":"0001641354","reported_name":"Omega Fund V, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":128202,"kind":"organization","name":"Omega Fund V GP, L.P.","position":2,"cik":"0001641355","reported_name":"Omega Fund V GP, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":128203,"kind":"organization","name":"Omega Fund V GP Manager, Ltd.","position":3,"cik":"0001641348","reported_name":"Omega Fund V GP Manager, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":108426,"kind":"person","name":"Paster Anne-Mari","position":4,"cik":"0001652863","reported_name":"Paster Anne-Mari","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":108425,"kind":"person","name":"Nessi Claudio","position":5,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":36727,"kind":"person","name":"Stampacchia Otello","position":6,"cik":"0001361712","reported_name":"Stampacchia Otello","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Convertible Promissory Note","published_at":"2020-10-16T15:58:44.000Z","date":"2020-10-14","kind":"exercise","acquired":false,"price":0,"reported_value":5915729.63,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The convertible promissory note automatically converted into shares of the Issuer's common stock upon the closing of the Issuer's initial public offering."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"Otello Stampacchia, a director of the Issuer, Claudio Nessi and Anne-Mari Paster are the directors of Omega Fund V GP Manager, Ltd. (\"Omega Manager\"), which is the sole general partner of Omega V Fund GP, L.P. (\"Omega GP\"), which is the sole general partner of Omega Fund V, L.P. (\"Omega L.P.\"). Such individuals may be deemed to share voting and dispositive power over the shares held by Omega L.P. Such individuals, together with Omega GP and Omega Manager, disclaim beneficial ownership of the shares held by Omega L.P. except to the extent of their respective pecuniary interests therein."}],"balance_after":0,"derivative":{"exercise_price":16.15,"expiration_date":"2022-02-20","underlying":"Common Stock","underlying_shares":366299},"source":{"system":"sec-edgar","filing":"0001209191-20-055046","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1722050/000120919120055046/doc4.xml","form_type":"4"}},{"id":3005366,"issuer":{"id":78257,"kind":"organization","name":"Kronos Bio, Inc.","symbol":"KRON"},"owners":[{"id":128201,"kind":"organization","name":"Omega Fund V, L.P.","position":1,"cik":"0001641354","reported_name":"Omega Fund V, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":128202,"kind":"organization","name":"Omega Fund V GP, L.P.","position":2,"cik":"0001641355","reported_name":"Omega Fund V GP, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":128203,"kind":"organization","name":"Omega Fund V GP Manager, Ltd.","position":3,"cik":"0001641348","reported_name":"Omega Fund V GP Manager, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":108426,"kind":"person","name":"Paster Anne-Mari","position":4,"cik":"0001652863","reported_name":"Paster Anne-Mari","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":108425,"kind":"person","name":"Nessi Claudio","position":5,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":36727,"kind":"person","name":"Stampacchia Otello","position":6,"cik":"0001361712","reported_name":"Stampacchia Otello","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Series A Preferred Stock","published_at":"2020-10-16T15:58:44.000Z","date":"2020-10-14","kind":"exercise","acquired":false,"shares":1304563,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each share of Series Seed Preferred Stock and Series A Preferred Stock (the \"Preferred Stock\") automatically converted into 1.055 shares of Common Stock upon the closing of the Issuer's initial public offering. The Preferred Stock had no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each share of Series Seed Preferred Stock and Series A Preferred Stock (the \"Preferred Stock\") automatically converted into 1.055 shares of Common Stock upon the closing of the Issuer's initial public offering. The Preferred Stock had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Each share of Series Seed Preferred Stock and Series A Preferred Stock (the \"Preferred Stock\") automatically converted into 1.055 shares of Common Stock upon the closing of the Issuer's initial public offering. The Preferred Stock had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Each share of Series Seed Preferred Stock and Series A Preferred Stock (the \"Preferred Stock\") automatically converted into 1.055 shares of Common Stock upon the closing of the Issuer's initial public offering. The Preferred Stock had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"Otello Stampacchia, a director of the Issuer, Claudio Nessi and Anne-Mari Paster are the directors of Omega Fund V GP Manager, Ltd. (\"Omega Manager\"), which is the sole general partner of Omega V Fund GP, L.P. (\"Omega GP\"), which is the sole general partner of Omega Fund V, L.P. (\"Omega L.P.\"). Such individuals may be deemed to share voting and dispositive power over the shares held by Omega L.P. Such individuals, together with Omega GP and Omega Manager, disclaim beneficial ownership of the shares held by Omega L.P. except to the extent of their respective pecuniary interests therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":1376313},"source":{"system":"sec-edgar","filing":"0001209191-20-055046","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1722050/000120919120055046/doc4.xml","form_type":"4"}},{"id":3005365,"issuer":{"id":78257,"kind":"organization","name":"Kronos Bio, Inc.","symbol":"KRON"},"owners":[{"id":128201,"kind":"organization","name":"Omega Fund V, L.P.","position":1,"cik":"0001641354","reported_name":"Omega Fund V, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":128202,"kind":"organization","name":"Omega Fund V GP, L.P.","position":2,"cik":"0001641355","reported_name":"Omega Fund V GP, L.P.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":128203,"kind":"organization","name":"Omega Fund V GP Manager, Ltd.","position":3,"cik":"0001641348","reported_name":"Omega Fund V GP Manager, Ltd.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":108426,"kind":"person","name":"Paster Anne-Mari","position":4,"cik":"0001652863","reported_name":"Paster Anne-Mari","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":108425,"kind":"person","name":"Nessi Claudio","position":5,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":36727,"kind":"person","name":"Stampacchia Otello","position":6,"cik":"0001361712","reported_name":"Stampacchia Otello","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Series Seed Preferred Stock","published_at":"2020-10-16T15:58:44.000Z","date":"2020-10-14","kind":"exercise","acquired":false,"shares":1522484,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"Each share of Series Seed Preferred Stock and Series A Preferred Stock (the \"Preferred Stock\") automatically converted into 1.055 shares of Common Stock upon the closing of the Issuer's initial public offering. The Preferred Stock had no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"Each share of Series Seed Preferred Stock and Series A Preferred Stock (the \"Preferred Stock\") automatically converted into 1.055 shares of Common Stock upon the closing of the Issuer's initial public offering. The Preferred Stock had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"Each share of Series Seed Preferred Stock and Series A Preferred Stock (the \"Preferred Stock\") automatically converted into 1.055 shares of Common Stock upon the closing of the Issuer's initial public offering. The Preferred Stock had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"Each share of Series Seed Preferred Stock and Series A Preferred Stock (the \"Preferred Stock\") automatically converted into 1.055 shares of Common Stock upon the closing of the Issuer's initial public offering. The Preferred Stock had no expiration date."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F1","text":"Each share of Series Seed Preferred Stock and Series A Preferred Stock (the \"Preferred Stock\") automatically converted into 1.055 shares of Common Stock upon the closing of the Issuer's initial public offering. The Preferred Stock had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"Otello Stampacchia, a director of the Issuer, Claudio Nessi and Anne-Mari Paster are the directors of Omega Fund V GP Manager, Ltd. (\"Omega Manager\"), which is the sole general partner of Omega V Fund GP, L.P. (\"Omega GP\"), which is the sole general partner of Omega Fund V, L.P. (\"Omega L.P.\"). Such individuals may be deemed to share voting and dispositive power over the shares held by Omega L.P. 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This Amendment to Form 4 is filed solely to correct the share number."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option becomes exercisable as to 33.3333% of the shares underlying the award on the first anniversary of the date of grant, with the remainder vesting in equal monthly installments until the third anniversary of the date of grant, subject to the Reporting Person's continued service as a director through each applicable vesting date."}],"balance_after":25000,"derivative":{"exercise_price":10,"expiration_date":"2027-11-14","underlying":"Common Stock","underlying_shares":25000},"source":{"system":"sec-edgar","filing":"0001209191-18-016583","document":"doc4a.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1722050/000120919118016583/doc4a.xml","form_type":"4/A","original_submission_date":"2017-12-01"}},{"id":4146218,"issuer":{"id":5638,"kind":"organization","name":"X4 Pharmaceuticals, Inc","symbol":"XFOR"},"owners":[{"id":108425,"kind":"person","name":"Nessi Claudio","position":1,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Stock Option (right to buy)","published_at":"2017-12-01T17:19:02.000Z","date":"2017-11-15","kind":"grant","acquired":true,"shares":7324,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"security","element":"securityTitle","label":"F1","text":"Consists of an automatic stock option grant that was made on November 15, 2017, the date of the effectiveness of the registration statement for the issuer's initial public offering, under the issuer's director compensation program."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The option becomes exercisable as to 33.3333% of the shares underlying the award on the first anniversary of the date of grant, with the remainder vesting in equal monthly installments until the third anniversary of the date of grant, subject to the Reporting Person's continued service as a director through each applicable vesting date."}],"balance_after":7324,"derivative":{"exercise_price":10,"expiration_date":"2027-11-14","underlying":"Common Stock","underlying_shares":7324},"source":{"system":"sec-edgar","filing":"0000899243-17-027823","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1722050/000089924317027823/doc4.xml","form_type":"4"}},{"id":4156628,"issuer":{"id":5638,"kind":"organization","name":"X4 Pharmaceuticals, Inc","symbol":"XFOR"},"owners":[{"id":108425,"kind":"person","name":"Nessi Claudio","position":1,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Series D Convertible Preferred Stock","published_at":"2017-11-20T17:43:36.000Z","date":"2017-11-20","kind":"exercise","acquired":false,"shares":952497,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F3","text":"The Series D Convertible Preferred Stock converted into Common Stock on a 0.29300-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series D Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing at the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"The Series D Convertible Preferred Stock converted into Common Stock on a 0.29300-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series D Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing at the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F3","text":"The Series D Convertible Preferred Stock converted into Common Stock on a 0.29300-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series D Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing at the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The reported securities are held of record by NeoMed Innovation V L.P.  Claudio Nessi, a member of our board of directors, is the Managing Partner of NeoMed Management (Jersey) Limited, which is the Investment Manager to NeoMed Innovation V L.P. By virtue of such relationship, Dr. Nessi may be deemed to have voting and investment power with respect to the shares held by NeoMed Innovation V L.P. Dr. Nessi disclaims beneficial ownership of the shares held by NeoMed Innovation V L.P., except to the extent of its his pecuniary interest therein, if any."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":279079},"source":{"system":"sec-edgar","filing":"0000899243-17-027016","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":7,"url":"https://www.sec.gov/Archives/edgar/data/1722050/000089924317027016/doc4.xml","form_type":"4"}},{"id":4156627,"issuer":{"id":5638,"kind":"organization","name":"X4 Pharmaceuticals, Inc","symbol":"XFOR"},"owners":[{"id":108425,"kind":"person","name":"Nessi Claudio","position":1,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Series C Convertible Preferred Stock","published_at":"2017-11-20T17:43:36.000Z","date":"2017-11-20","kind":"exercise","acquired":false,"shares":84040,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F2","text":"The Series C Convertible Preferred Stock converted into Common Stock on a 0.49832-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series C Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing at the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"The Series C Convertible Preferred Stock converted into Common Stock on a 0.49832-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series C Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing at the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F2","text":"The Series C Convertible Preferred Stock converted into Common Stock on a 0.49832-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series C Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing at the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The reported securities are held of record by NeoMed Innovation V L.P.  Claudio Nessi, a member of our board of directors, is the Managing Partner of NeoMed Management (Jersey) Limited, which is the Investment Manager to NeoMed Innovation V L.P. By virtue of such relationship, Dr. Nessi may be deemed to have voting and investment power with respect to the shares held by NeoMed Innovation V L.P. Dr. Nessi disclaims beneficial ownership of the shares held by NeoMed Innovation V L.P., except to the extent of its his pecuniary interest therein, if any."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":41878},"source":{"system":"sec-edgar","filing":"0000899243-17-027016","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1722050/000089924317027016/doc4.xml","form_type":"4"}},{"id":4156626,"issuer":{"id":5638,"kind":"organization","name":"X4 Pharmaceuticals, Inc","symbol":"XFOR"},"owners":[{"id":108425,"kind":"person","name":"Nessi Claudio","position":1,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Series B Convertible Preferred Stock","published_at":"2017-11-20T17:43:36.000Z","date":"2017-11-20","kind":"exercise","acquired":false,"shares":552487,"price":0,"value":0.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"The Series B Convertible Preferred Stock converted into Common Stock on a 0.44650-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series B Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing at the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The Series B Convertible Preferred Stock converted into Common Stock on a 0.44650-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series B Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing at the Issuer's initial public offering. The shares had no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"The Series B Convertible Preferred Stock converted into Common Stock on a 0.44650-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series B Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing at the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The reported securities are held of record by NeoMed Innovation V L.P.  Claudio Nessi, a member of our board of directors, is the Managing Partner of NeoMed Management (Jersey) Limited, which is the Investment Manager to NeoMed Innovation V L.P. By virtue of such relationship, Dr. Nessi may be deemed to have voting and investment power with respect to the shares held by NeoMed Innovation V L.P. Dr. Nessi disclaims beneficial ownership of the shares held by NeoMed Innovation V L.P., except to the extent of its his pecuniary interest therein, if any."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":246682},"source":{"system":"sec-edgar","filing":"0000899243-17-027016","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1722050/000089924317027016/doc4.xml","form_type":"4"}},{"id":4156625,"issuer":{"id":5638,"kind":"organization","name":"X4 Pharmaceuticals, Inc","symbol":"XFOR"},"owners":[{"id":108425,"kind":"person","name":"Nessi Claudio","position":1,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2017-11-20T17:43:36.000Z","date":"2017-11-20","kind":"purchase","acquired":true,"shares":300000,"price":10,"value":3000000.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The reported securities are held of record by NeoMed Innovation V L.P.  Claudio Nessi, a member of our board of directors, is the Managing Partner of NeoMed Management (Jersey) Limited, which is the Investment Manager to NeoMed Innovation V L.P. By virtue of such relationship, Dr. Nessi may be deemed to have voting and investment power with respect to the shares held by NeoMed Innovation V L.P. Dr. Nessi disclaims beneficial ownership of the shares held by NeoMed Innovation V L.P., except to the extent of its his pecuniary interest therein, if any."}],"balance_after":867639,"source":{"system":"sec-edgar","filing":"0000899243-17-027016","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1722050/000089924317027016/doc4.xml","form_type":"4"}},{"id":4156624,"issuer":{"id":5638,"kind":"organization","name":"X4 Pharmaceuticals, Inc","symbol":"XFOR"},"owners":[{"id":108425,"kind":"person","name":"Nessi Claudio","position":1,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2017-11-20T17:43:36.000Z","date":"2017-11-20","kind":"exercise","acquired":true,"shares":279079,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The Series D Convertible Preferred Stock converted into Common Stock on a 0.29300-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series D Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing at the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The reported securities are held of record by NeoMed Innovation V L.P.  Claudio Nessi, a member of our board of directors, is the Managing Partner of NeoMed Management (Jersey) Limited, which is the Investment Manager to NeoMed Innovation V L.P. By virtue of such relationship, Dr. Nessi may be deemed to have voting and investment power with respect to the shares held by NeoMed Innovation V L.P. Dr. Nessi disclaims beneficial ownership of the shares held by NeoMed Innovation V L.P., except to the extent of its his pecuniary interest therein, if any."}],"balance_after":567639,"source":{"system":"sec-edgar","filing":"0000899243-17-027016","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1722050/000089924317027016/doc4.xml","form_type":"4"}},{"id":4156623,"issuer":{"id":5638,"kind":"organization","name":"X4 Pharmaceuticals, Inc","symbol":"XFOR"},"owners":[{"id":108425,"kind":"person","name":"Nessi Claudio","position":1,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2017-11-20T17:43:36.000Z","date":"2017-11-20","kind":"exercise","acquired":true,"shares":41878,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The Series C Convertible Preferred Stock converted into Common Stock on a 0.49832-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series C Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing at the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The reported securities are held of record by NeoMed Innovation V L.P.  Claudio Nessi, a member of our board of directors, is the Managing Partner of NeoMed Management (Jersey) Limited, which is the Investment Manager to NeoMed Innovation V L.P. By virtue of such relationship, Dr. Nessi may be deemed to have voting and investment power with respect to the shares held by NeoMed Innovation V L.P. Dr. Nessi disclaims beneficial ownership of the shares held by NeoMed Innovation V L.P., except to the extent of its his pecuniary interest therein, if any."}],"balance_after":288560,"source":{"system":"sec-edgar","filing":"0000899243-17-027016","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1722050/000089924317027016/doc4.xml","form_type":"4"}},{"id":4156622,"issuer":{"id":5638,"kind":"organization","name":"X4 Pharmaceuticals, Inc","symbol":"XFOR"},"owners":[{"id":108425,"kind":"person","name":"Nessi Claudio","position":1,"cik":"0001722050","reported_name":"Nessi Claudio","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Common Stock","published_at":"2017-11-20T17:43:36.000Z","date":"2017-11-20","kind":"exercise","acquired":true,"shares":246682,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The Series B Convertible Preferred Stock converted into Common Stock on a 0.44650-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration. The Series B Convertible Preferred Stock was convertible at any time at the holder's election and automatically upon the closing at the Issuer's initial public offering. The shares had no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The reported securities are held of record by NeoMed Innovation V L.P.  Claudio Nessi, a member of our board of directors, is the Managing Partner of NeoMed Management (Jersey) Limited, which is the Investment Manager to NeoMed Innovation V L.P. By virtue of such relationship, Dr. Nessi may be deemed to have voting and investment power with respect to the shares held by NeoMed Innovation V L.P. Dr. Nessi disclaims beneficial ownership of the shares held by NeoMed Innovation V L.P., except to the extent of its his pecuniary interest therein, if any."}],"balance_after":246682,"source":{"system":"sec-edgar","filing":"0000899243-17-027016","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1722050/000089924317027016/doc4.xml","form_type":"4"}}]}