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These shares were sold in multiple transactions ranging from $0.5691 to $0.68 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The securities are directly held by SR One Co-Invest I, LLC (\"SR One Co-Invest I\"). SR One Co-Invest I Manager, LLC (\"SR One Co-Invest I Manager\") is the managing member of SR One Co-Invest I and SR One Capital Management is the managing member of SR One Co-Invest I Manager. Dr. George is the managing member of SR One Capital Management (SR One Co-Invest I Manager, SR One Capital Management, and Dr. George together, the \"Co-Invest I Indirect Reporting Persons\"). The Co-Invest I Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 or otherwise of such portion of the securities held by SR One Co-Invest I in which the Co-Invest I Indirect Reporting Persons have no pecuniary interest."}],"balance_after":1821415,"source":{"system":"sec-edgar","filing":"0001209191-23-056920","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1864915/000120919123056920/doc4.xml","form_type":"4"}},{"id":1728092,"issuer":{"id":89916,"kind":"organization","name":"eFFECTOR Therapeutics, Inc.","symbol":"EFTR"},"owners":[{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":1,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":2,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":3,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107922,"kind":"organization","name":"SR One Co-Invest I, LLC","position":4,"cik":"0001864915","reported_name":"SR One Co-Invest I, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107923,"kind":"organization","name":"SR One Co-Invest I Manager, LLC","position":5,"cik":"0001881204","reported_name":"SR One Co-Invest I Manager, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":39164,"kind":"person","name":"George Simeon","position":6,"cik":"0001595117","reported_name":"George Simeon","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2023-11-29T17:07:06.000Z","date":"2023-11-27","kind":"sale","planned":false,"acquired":false,"shares":430578,"price":0.6065,"value":261145.557,"ownership":{"direct":false,"nature":"See Note 2"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions ranging from $0.5691 to $0.68 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are directly held by SR One Capital Fund I Aggregator, LP (\"SR One Fund I Aggregator\"). SR One Capital Partners I, LP (\"SR One Partners I\") is the sole general partner of SR One Fund I Aggregator, and SR One Capital Management, LLC (\"SR One Capital Management\") is the sole general partner of SR One Partners I. Simeon George, M.D. is the managing member of SR One Capital Management (SR One Partners I, SR One Capital Management, and Dr. George together, the \"Fund I Indirect Reporting Persons\"). The Fund I Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended (\"Section 16\"), or otherwise of such portion of the securities held by SR One Fund I Aggregator in which the Fund I Indirect Reporting Persons have no pecuniary interest."}],"balance_after":4391536,"source":{"system":"sec-edgar","filing":"0001209191-23-056920","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1864915/000120919123056920/doc4.xml","form_type":"4"}},{"id":1893690,"issuer":{"id":15294,"kind":"organization","name":"Arcellx, Inc.","symbol":"ACLX"},"owners":[{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":1,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":2,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":3,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":39164,"kind":"person","name":"George Simeon","position":4,"cik":"0001595117","reported_name":"George Simeon","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113514,"kind":"organization","name":"SR One Co-Invest II, LLC","position":5,"cik":"0001867644","reported_name":"SR One Co-Invest II, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113515,"kind":"organization","name":"SR One Co-Invest II Manager, LLC","position":6,"cik":"0001910324","reported_name":"SR One Co-Invest II Manager, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2023-05-15T22:16:52.000Z","date":"2023-05-11","kind":"sale","planned":false,"acquired":false,"shares":3804,"price":46.15,"value":175554.6,"ownership":{"direct":false,"nature":"See Note 3"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $46.00 to $46.56 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The securities are directly held by SR One Co-Invest II, LLC (\"SR One Co-Invest II\"). SR One Co-Invest II Manager, LLC (\"SR One Co-Invest II Manager\") is the managing member of SR One Co-Invest II and SR One Capital Management is the managing member of SR One Co-Invest II Manager. Dr. George is the managing member of SR One Capital Management (SR One Co-Invest II Manager, SR One Capital Management, and Dr. George together, the \"Co-Invest II Indirect Reporting Persons\"). The Co-Invest II Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 or otherwise of such portion of the securities held by SR One Co-Invest II in which the Co-Invest II Indirect Reporting Persons have no pecuniary interest."}],"balance_after":1658780,"source":{"system":"sec-edgar","filing":"0001209191-23-029610","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919123029610/doc4.xml","form_type":"4"}},{"id":1893689,"issuer":{"id":15294,"kind":"organization","name":"Arcellx, Inc.","symbol":"ACLX"},"owners":[{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":1,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":2,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":3,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":39164,"kind":"person","name":"George Simeon","position":4,"cik":"0001595117","reported_name":"George Simeon","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113514,"kind":"organization","name":"SR One Co-Invest II, LLC","position":5,"cik":"0001867644","reported_name":"SR One Co-Invest II, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113515,"kind":"organization","name":"SR One Co-Invest II Manager, LLC","position":6,"cik":"0001910324","reported_name":"SR One Co-Invest II Manager, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2023-05-15T22:16:52.000Z","date":"2023-05-11","kind":"sale","planned":false,"acquired":false,"shares":6485,"price":46.15,"value":299282.75,"ownership":{"direct":false,"nature":"See Note 2"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $46.00 to $46.56 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the SEC, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are directly held by SR One Capital Fund I Aggregator, LP (\"SR One Fund I Aggregator\"). SR One Capital Partners I, LP (\"SR One Partners I\") is the sole general partner of SR One Fund I Aggregator, and SR One Capital Management, LLC (\"SR One Capital Management\") is the sole general partner of SR One Partners I. Simeon George, M.D. is the managing member of SR One Capital Management (SR One Partners I, SR One Capital Management, and Dr. George together, the \"Fund I Indirect Reporting Persons\"). The Fund I Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended (\"Section 16\"), or otherwise of such portion of the securities held by SR One Fund I Aggregator in which the Fund I Indirect Reporting Persons have no pecuniary interest."}],"balance_after":2828394,"source":{"system":"sec-edgar","filing":"0001209191-23-029610","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919123029610/doc4.xml","form_type":"4"}},{"id":1893688,"issuer":{"id":15294,"kind":"organization","name":"Arcellx, Inc.","symbol":"ACLX"},"owners":[{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":1,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":2,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":3,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":39164,"kind":"person","name":"George Simeon","position":4,"cik":"0001595117","reported_name":"George Simeon","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113514,"kind":"organization","name":"SR One Co-Invest II, LLC","position":5,"cik":"0001867644","reported_name":"SR One Co-Invest II, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113515,"kind":"organization","name":"SR One Co-Invest II Manager, LLC","position":6,"cik":"0001910324","reported_name":"SR One Co-Invest II Manager, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2023-05-15T22:16:52.000Z","date":"2023-05-11","kind":"sale","planned":false,"acquired":false,"shares":370612,"price":45,"value":16677540.0,"ownership":{"direct":false,"nature":"See Note 3"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $45.00 to $45.745 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission (the \"SEC\"), upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The securities are directly held by SR One Co-Invest II, LLC (\"SR One Co-Invest II\"). SR One Co-Invest II Manager, LLC (\"SR One Co-Invest II Manager\") is the managing member of SR One Co-Invest II and SR One Capital Management is the managing member of SR One Co-Invest II Manager. Dr. George is the managing member of SR One Capital Management (SR One Co-Invest II Manager, SR One Capital Management, and Dr. George together, the \"Co-Invest II Indirect Reporting Persons\"). The Co-Invest II Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 or otherwise of such portion of the securities held by SR One Co-Invest II in which the Co-Invest II Indirect Reporting Persons have no pecuniary interest."}],"balance_after":1662584,"source":{"system":"sec-edgar","filing":"0001209191-23-029610","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919123029610/doc4.xml","form_type":"4"}},{"id":1893687,"issuer":{"id":15294,"kind":"organization","name":"Arcellx, Inc.","symbol":"ACLX"},"owners":[{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":1,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":2,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":3,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":39164,"kind":"person","name":"George Simeon","position":4,"cik":"0001595117","reported_name":"George Simeon","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113514,"kind":"organization","name":"SR One Co-Invest II, LLC","position":5,"cik":"0001867644","reported_name":"SR One Co-Invest II, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113515,"kind":"organization","name":"SR One Co-Invest II Manager, LLC","position":6,"cik":"0001910324","reported_name":"SR One Co-Invest II Manager, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2023-05-15T22:16:52.000Z","date":"2023-05-11","kind":"sale","planned":false,"acquired":false,"shares":631932,"price":45,"value":28436940.0,"ownership":{"direct":false,"nature":"See Note 2"},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The reported price in Column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $45.00 to $45.745 per share, inclusive. The Reporting Person undertakes to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission (the \"SEC\"), upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The securities are directly held by SR One Capital Fund I Aggregator, LP (\"SR One Fund I Aggregator\"). SR One Capital Partners I, LP (\"SR One Partners I\") is the sole general partner of SR One Fund I Aggregator, and SR One Capital Management, LLC (\"SR One Capital Management\") is the sole general partner of SR One Partners I. Simeon George, M.D. is the managing member of SR One Capital Management (SR One Partners I, SR One Capital Management, and Dr. George together, the \"Fund I Indirect Reporting Persons\"). The Fund I Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended (\"Section 16\"), or otherwise of such portion of the securities held by SR One Fund I Aggregator in which the Fund I Indirect Reporting Persons have no pecuniary interest."}],"balance_after":2834879,"source":{"system":"sec-edgar","filing":"0001209191-23-029610","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919123029610/doc4.xml","form_type":"4"}},{"id":2079977,"issuer":{"id":4991,"kind":"organization","name":"Design Therapeutics, Inc."},"owners":[{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":1,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":2,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":3,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2022-12-20T23:37:12.000Z","date":"2022-12-20","kind":"purchase","acquired":true,"shares":40000,"price":8.1358,"value":325432.0,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The reported price in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $7.86 to $8.45 per share, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by SR One Capital Fund I Aggregator, LP (\"SR One Fund I Aggregator\"). SR One Capital Partners I, LP (\"SR One Partners I\") is the sole general partner of SR One Fund I Aggregator, and SR One Capital Management, LLC (\"SR One Capital Management\") is the sole general partner of SR One Partners I. Simeon George, M.D. is the managing member of SR One Capital Management (SR One Partners I, SR One Capital Management, and Dr. George together, the \"Indirect Reporting Persons\"). The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended (\"Section 16\"), or otherwise of such portion of the securities held by SR One Fund I Aggregator in which the Indirect Reporting Persons have no pecuniary interest, and this report shall not be deemed an admission that the Indirect Reporting Persons are the beneficial owners of such securities for Section 16 or any other purpose."}],"balance_after":6526476,"source":{"system":"sec-edgar","filing":"0001209191-22-062226","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919122062226/doc4.xml","form_type":"4"}},{"id":2079976,"issuer":{"id":4991,"kind":"organization","name":"Design Therapeutics, Inc."},"owners":[{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":1,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":2,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":3,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2022-12-20T23:37:12.000Z","date":"2022-12-19","kind":"purchase","acquired":true,"shares":360000,"price":8.6336,"value":3108096.0,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The reported price in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $8.25 to $8.90 per share, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by SR One Capital Fund I Aggregator, LP (\"SR One Fund I Aggregator\"). SR One Capital Partners I, LP (\"SR One Partners I\") is the sole general partner of SR One Fund I Aggregator, and SR One Capital Management, LLC (\"SR One Capital Management\") is the sole general partner of SR One Partners I. Simeon George, M.D. is the managing member of SR One Capital Management (SR One Partners I, SR One Capital Management, and Dr. George together, the \"Indirect Reporting Persons\"). The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended (\"Section 16\"), or otherwise of such portion of the securities held by SR One Fund I Aggregator in which the Indirect Reporting Persons have no pecuniary interest, and this report shall not be deemed an admission that the Indirect Reporting Persons are the beneficial owners of such securities for Section 16 or any other purpose."}],"balance_after":6486476,"source":{"system":"sec-edgar","filing":"0001209191-22-062226","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919122062226/doc4.xml","form_type":"4"}},{"id":2079975,"issuer":{"id":4991,"kind":"organization","name":"Design Therapeutics, Inc."},"owners":[{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":1,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":2,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":3,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2022-12-20T23:37:12.000Z","date":"2022-12-16","kind":"purchase","acquired":true,"shares":500000,"price":8.2811,"value":4140550.0,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The reported price in Column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $7.90 to $8.76 per share, inclusive. The Reporting Persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the range set forth in this footnote."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The securities are directly held by SR One Capital Fund I Aggregator, LP (\"SR One Fund I Aggregator\"). SR One Capital Partners I, LP (\"SR One Partners I\") is the sole general partner of SR One Fund I Aggregator, and SR One Capital Management, LLC (\"SR One Capital Management\") is the sole general partner of SR One Partners I. Simeon George, M.D. is the managing member of SR One Capital Management (SR One Partners I, SR One Capital Management, and Dr. George together, the \"Indirect Reporting Persons\"). The Indirect Reporting Persons disclaim beneficial ownership within the meaning of Section 16 of the Securities Exchange Act of 1934, as amended (\"Section 16\"), or otherwise of such portion of the securities held by SR One Fund I Aggregator in which the Indirect Reporting Persons have no pecuniary interest, and this report shall not be deemed an admission that the Indirect Reporting Persons are the beneficial owners of such securities for Section 16 or any other purpose."}],"balance_after":6126476,"source":{"system":"sec-edgar","filing":"0001209191-22-062226","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919122062226/doc4.xml","form_type":"4"}},{"id":2404526,"issuer":{"id":15294,"kind":"organization","name":"Arcellx, Inc.","symbol":"ACLX"},"owners":[{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":1,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":2,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":3,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113514,"kind":"organization","name":"SR One Co-Invest II, LLC","position":4,"cik":"0001867644","reported_name":"SR One Co-Invest II, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":39164,"kind":"person","name":"George Simeon","position":5,"cik":"0001595117","reported_name":"George Simeon","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113515,"kind":"organization","name":"SR One Co-Invest II Manager, LLC","position":6,"cik":"0001910324","reported_name":"SR One Co-Invest II Manager, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series C Preferred Stock","published_at":"2022-02-10T13:41:09.000Z","date":"2022-02-08","kind":"exercise","acquired":false,"shares":433196,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The reported securities are held directly by SR One Co-Invest II, LLC. SR One Co-Invest Manager II, LLC is the managing member of SR One Co-Invest II, LLC, and SR One Capital Management, LLC is the managing member of SR One Co-Invest Manager II, LLC.  Simeon George is the managing member of SR One Capital Management, LLC.  Each of SR One Co-Invest Manager II, LLC, SR One Capital Management, LLC and Mr. George may each be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":433196},"source":{"system":"sec-edgar","filing":"0001209191-22-008281","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":12,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919122008281/doc4.xml","form_type":"4"}},{"id":2404525,"issuer":{"id":15294,"kind":"organization","name":"Arcellx, Inc.","symbol":"ACLX"},"owners":[{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":1,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":2,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":3,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113514,"kind":"organization","name":"SR One Co-Invest II, LLC","position":4,"cik":"0001867644","reported_name":"SR One Co-Invest II, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":39164,"kind":"person","name":"George Simeon","position":5,"cik":"0001595117","reported_name":"George Simeon","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113515,"kind":"organization","name":"SR One Co-Invest II Manager, LLC","position":6,"cik":"0001910324","reported_name":"SR One Co-Invest II Manager, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series C Preferred Stock","published_at":"2022-02-10T13:41:09.000Z","date":"2022-02-08","kind":"exercise","acquired":false,"shares":649795,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reported securities are held directly by SR One Capital Fund I Aggregator, LP. SR One Capital Partners I, LP is the general partner of SR One Capital Fund I Aggregator, LP, and SR One Capital Management, LLC is the general partner of SR One Capital Partners I, LP.  Simeon George is the managing member of SR One Capital Management, LLC.  Each of SR One Capital Partners I, LP, SR One Capital Management, LLC and Mr. George may each be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":649795},"source":{"system":"sec-edgar","filing":"0001209191-22-008281","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":11,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919122008281/doc4.xml","form_type":"4"}},{"id":2404524,"issuer":{"id":15294,"kind":"organization","name":"Arcellx, Inc.","symbol":"ACLX"},"owners":[{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":1,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":2,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":3,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113514,"kind":"organization","name":"SR One Co-Invest II, LLC","position":4,"cik":"0001867644","reported_name":"SR One Co-Invest II, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":39164,"kind":"person","name":"George Simeon","position":5,"cik":"0001595117","reported_name":"George Simeon","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113515,"kind":"organization","name":"SR One Co-Invest II Manager, LLC","position":6,"cik":"0001910324","reported_name":"SR One Co-Invest II Manager, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series B-2 Preferred Stock","published_at":"2022-02-10T13:41:09.000Z","date":"2022-02-08","kind":"exercise","acquired":false,"shares":533389,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reported securities are held directly by SR One Capital Fund I Aggregator, LP. SR One Capital Partners I, LP is the general partner of SR One Capital Fund I Aggregator, LP, and SR One Capital Management, LLC is the general partner of SR One Capital Partners I, LP.  Simeon George is the managing member of SR One Capital Management, LLC.  Each of SR One Capital Partners I, LP, SR One Capital Management, LLC and Mr. George may each be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":533389},"source":{"system":"sec-edgar","filing":"0001209191-22-008281","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":10,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919122008281/doc4.xml","form_type":"4"}},{"id":2404523,"issuer":{"id":15294,"kind":"organization","name":"Arcellx, Inc.","symbol":"ACLX"},"owners":[{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":1,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":2,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":3,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113514,"kind":"organization","name":"SR One Co-Invest II, LLC","position":4,"cik":"0001867644","reported_name":"SR One Co-Invest II, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":39164,"kind":"person","name":"George Simeon","position":5,"cik":"0001595117","reported_name":"George Simeon","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113515,"kind":"organization","name":"SR One Co-Invest II Manager, LLC","position":6,"cik":"0001910324","reported_name":"SR One Co-Invest II Manager, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series B-1 Preferred Stock","published_at":"2022-02-10T13:41:09.000Z","date":"2022-02-08","kind":"exercise","acquired":false,"shares":666651,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reported securities are held directly by SR One Capital Fund I Aggregator, LP. SR One Capital Partners I, LP is the general partner of SR One Capital Fund I Aggregator, LP, and SR One Capital Management, LLC is the general partner of SR One Capital Partners I, LP.  Simeon George is the managing member of SR One Capital Management, LLC.  Each of SR One Capital Partners I, LP, SR One Capital Management, LLC and Mr. George may each be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":666651},"source":{"system":"sec-edgar","filing":"0001209191-22-008281","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":9,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919122008281/doc4.xml","form_type":"4"}},{"id":2404522,"issuer":{"id":15294,"kind":"organization","name":"Arcellx, Inc.","symbol":"ACLX"},"owners":[{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":1,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":2,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":3,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113514,"kind":"organization","name":"SR One Co-Invest II, LLC","position":4,"cik":"0001867644","reported_name":"SR One Co-Invest II, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":39164,"kind":"person","name":"George Simeon","position":5,"cik":"0001595117","reported_name":"George Simeon","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113515,"kind":"organization","name":"SR One Co-Invest II Manager, LLC","position":6,"cik":"0001910324","reported_name":"SR One Co-Invest II Manager, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Series A Preferred Stock","published_at":"2022-02-10T13:41:09.000Z","date":"2022-02-08","kind":"exercise","acquired":false,"shares":1550309,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"derivative.exercise_price","element":"conversionOrExercisePrice","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"price","element":"transactionPricePerShare","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"derivative.expiration_date","element":"expirationDate","label":"F1","text":"All outstanding shares of Preferred Stock will automatically convert into shares of Common Stock at the Reporting Person's election and automatically upon the closing of the initial public offering of Arcellx, Inc. (the \"Issuer\").  The Preferred Stock has no expiration date."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"The reported securities are held directly by SR One Capital Fund I Aggregator, LP. SR One Capital Partners I, LP is the general partner of SR One Capital Fund I Aggregator, LP, and SR One Capital Management, LLC is the general partner of SR One Capital Partners I, LP.  Simeon George is the managing member of SR One Capital Management, LLC.  Each of SR One Capital Partners I, LP, SR One Capital Management, LLC and Mr. George may each be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":1550309},"source":{"system":"sec-edgar","filing":"0001209191-22-008281","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":8,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919122008281/doc4.xml","form_type":"4"}},{"id":2404521,"issuer":{"id":15294,"kind":"organization","name":"Arcellx, Inc.","symbol":"ACLX"},"owners":[{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":1,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":2,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":3,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113514,"kind":"organization","name":"SR One Co-Invest II, LLC","position":4,"cik":"0001867644","reported_name":"SR One Co-Invest II, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":39164,"kind":"person","name":"George Simeon","position":5,"cik":"0001595117","reported_name":"George Simeon","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":113515,"kind":"organization","name":"SR One Co-Invest II Manager, LLC","position":6,"cik":"0001910324","reported_name":"SR One Co-Invest II Manager, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2022-02-10T13:41:09.000Z","date":"2022-02-08","kind":"purchase","acquired":true,"shares":1600000,"price":15,"value":24000000.0,"ownership":{"direct":false,"nature":"See Footnote"},"footnotes":[{"field":"shares","element":"transactionShares","label":"F5","text":"SR One Co-Invest II, LLC purchased 1,600,000 shares of Common Stock of the Issuer in connection with the Issuer's public offering."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The reported securities are held directly by SR One Co-Invest II, LLC. SR One Co-Invest Manager II, LLC is the managing member of SR One Co-Invest II, LLC, and SR One Capital Management, LLC is the managing member of SR One Co-Invest Manager II, LLC.  Simeon George is the managing member of SR One Capital Management, LLC.  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Each of SR One Capital Partners I, LP, SR One Capital Management, LLC and Mr. George may each be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein."}],"balance_after":0,"derivative":{"underlying":"Common Stock","underlying_shares":4439839},"source":{"system":"sec-edgar","filing":"0001209191-21-024238","document":"doc4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919121024238/doc4.xml","form_type":"4"}},{"id":2764683,"issuer":{"id":4991,"kind":"organization","name":"Design Therapeutics, Inc."},"owners":[{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":1,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":2,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":3,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-04-01T22:23:16.000Z","date":"2021-03-30","kind":"purchase","acquired":true,"shares":250000,"price":20,"value":5000000.0,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F3","text":"SR One Capital Fund I Aggregator, LP purchased 250,000 shares of Common Stock of Design Therapeutics, Inc. (the \"Issuer\") in connection with the Issuer's public offering."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The reported securities are held directly by SR One Capital Fund I Aggregator, LP. SR One Capital Partners I, LP is the general partner of SR One Capital Fund I Aggregator, LP, and SR One Capital Management, LLC is the general partner of SR One Capital Partners I, LP.  Simeon George, M.D. is the managing member of SR One Capital Management, LLC.  Each of SR One Capital Partners I, LP, SR One Capital Management, LLC and Mr. George may each be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein."}],"balance_after":5626476,"source":{"system":"sec-edgar","filing":"0001209191-21-024238","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919121024238/doc4.xml","form_type":"4"}},{"id":2764682,"issuer":{"id":4991,"kind":"organization","name":"Design Therapeutics, Inc."},"owners":[{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":1,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":2,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":3,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-04-01T22:23:16.000Z","date":"2021-03-30","kind":"exercise","acquired":true,"shares":936637,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The Series A Preferred Stock and the Series B Preferred Stock were converted into Common Stock on a 1.63-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration.  The Series A Preferred Stock and Series B Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering.  The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The reported securities are held directly by SR One Capital Fund I Aggregator, LP. SR One Capital Partners I, LP is the general partner of SR One Capital Fund I Aggregator, LP, and SR One Capital Management, LLC is the general partner of SR One Capital Partners I, LP.  Simeon George, M.D. is the managing member of SR One Capital Management, LLC.  Each of SR One Capital Partners I, LP, SR One Capital Management, LLC and Mr. George may each be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein."}],"balance_after":5376476,"source":{"system":"sec-edgar","filing":"0001209191-21-024238","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919121024238/doc4.xml","form_type":"4"}},{"id":2764681,"issuer":{"id":4991,"kind":"organization","name":"Design Therapeutics, Inc."},"owners":[{"id":107920,"kind":"organization","name":"SR One Capital Fund I Aggregator LP","position":1,"cik":"0001848319","reported_name":"SR One Capital Fund I Aggregator LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":107921,"kind":"organization","name":"SR ONE CAPITAL PARTNERS I, LP","position":2,"cik":"0001853724","reported_name":"SR ONE CAPITAL PARTNERS I, LP","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}},{"id":48340,"kind":"organization","name":"SR ONE CAPITAL MANAGEMENT, LLC","position":3,"cik":"0001853723","reported_name":"SR ONE CAPITAL MANAGEMENT, LLC","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2021-04-01T22:23:16.000Z","date":"2021-03-30","kind":"exercise","acquired":true,"shares":4439839,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The Series A Preferred Stock and the Series B Preferred Stock were converted into Common Stock on a 1.63-for-one basis upon the closing of the Issuer's initial public offering without payment of consideration.  The Series A Preferred Stock and Series B Preferred Stock were convertible at any time at the holder's election and automatically upon the closing of the Issuer's initial public offering.  The shares had no expiration date."},{"field":"ownership.direct","element":"directOrIndirectOwnership","label":"F2","text":"The reported securities are held directly by SR One Capital Fund I Aggregator, LP. SR One Capital Partners I, LP is the general partner of SR One Capital Fund I Aggregator, LP, and SR One Capital Management, LLC is the general partner of SR One Capital Partners I, LP.  Simeon George, M.D. is the managing member of SR One Capital Management, LLC.  Each of SR One Capital Partners I, LP, SR One Capital Management, LLC and Mr. George may each be deemed to have shared power to vote or dispose of these shares, and each disclaims beneficial ownership of the shares except to the extent of any pecuniary interest therein."}],"balance_after":4439839,"source":{"system":"sec-edgar","filing":"0001209191-21-024238","document":"doc4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1853723/000120919121024238/doc4.xml","form_type":"4"}}]}