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The shares were sold in multiple transactions at prices ranging from $0.13 to $0.15, inclusive. Each sale price was below the purchase prices for the shares, and the reporting person engaged in the transactions for tax purposes and to cause his holdings to fall below 10% of the outstanding shares of the issuer's common stock and thereby cease being subject to the requirements of Section 16 of the Securities Exchange Act of 1934. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth above."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Consists of shares of common stock held in trusts for the benefit of the Reporting Person's children in which the Reporting Person is the trustee."}],"balance_after":74000,"source":{"system":"sec-edgar","filing":"0001553350-23-000471","document":"davidow.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/2002210/000155335023000471/davidow.xml","form_type":"4"}},{"id":1712826,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":96184,"kind":"person","name":"Davidow Robert L","position":1,"cik":"0002002210","reported_name":"Davidow Robert L","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2023-12-13T16:02:05.000Z","date":"2023-12-11","kind":"sale","planned":false,"acquired":false,"shares":18000,"price":0.15,"value":2700.0,"ownership":{"direct":false,"nature":"Joint account with spouse"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Consists of shares of common stock held in a joint account with the Reporting Person's wife."}],"balance_after":22000,"source":{"system":"sec-edgar","filing":"0001553350-23-000471","document":"davidow.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/2002210/000155335023000471/davidow.xml","form_type":"4"}},{"id":1712825,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":96184,"kind":"person","name":"Davidow Robert L","position":1,"cik":"0002002210","reported_name":"Davidow Robert L","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock","published_at":"2023-12-13T16:02:05.000Z","date":"2023-12-11","kind":"sale","planned":false,"acquired":false,"shares":264000,"price":0.14,"value":36960.0,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"The price reported in Column 4 is a weighted average price. The shares were sold in multiple transactions at prices ranging from $0.13 to $0.15, inclusive. Each sale price was below the purchase prices for the shares, and the reporting person engaged in the transactions for tax purposes and to cause his holdings to fall below 10% of the outstanding shares of the issuer's common stock and thereby cease being subject to the requirements of Section 16 of the Securities Exchange Act of 1934. The Reporting Person undertakes to provide to the issuer, any security holder of the issuer, or the staff of the Securities and Exchange Commission, upon request, full information regarding the number of shares sold at each separate price within the ranges set forth above."}],"balance_after":681000,"source":{"system":"sec-edgar","filing":"0001553350-23-000471","document":"davidow.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/2002210/000155335023000471/davidow.xml","form_type":"4"}},{"id":1783415,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":35267,"kind":"person","name":"ROSENWALD LINDSAY A MD","position":1,"cik":"0000941841","reported_name":"ROSENWALD LINDSAY A MD","relationship":{"director":true}}],"security":"Common Stock","published_at":"2023-09-12T13:03:33.000Z","date":"2023-09-08","kind":"purchase","planned":false,"acquired":true,"shares":348675,"price":0.72,"value":251046.0,"ownership":{"direct":true},"balance_after":354318,"source":{"system":"sec-edgar","filing":"0001437749-23-025643","document":"rdgdoc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/941841/000143774923025643/rdgdoc.xml","form_type":"4"}},{"id":1782866,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":6822,"kind":"organization","name":"Fortress Biotech, Inc.","position":1,"cik":"0001429260","reported_name":"Fortress Biotech, Inc.","relationship":{"ten_percent_owner":true}}],"security":"Common Stock","published_at":"2023-09-12T13:02:05.000Z","date":"2023-09-08","kind":"purchase","planned":false,"acquired":true,"shares":418410,"price":0.72,"value":301255.2,"ownership":{"direct":true},"balance_after":1032390,"source":{"system":"sec-edgar","filing":"0001437749-23-025640","document":"rdgdoc.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1429260/000143774923025640/rdgdoc.xml","form_type":"4"}},{"id":1835106,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":35634,"kind":"person","name":"Jin David","position":1,"cik":"0001930732","reported_name":"Jin David","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Interim PFO and COO"}}],"security":"Employee stock option (right to buy)","published_at":"2023-07-05T20:09:29.000Z","date":"2023-06-30","kind":"grant","planned":false,"acquired":true,"shares":250000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in accordance with the following schedule: (i) 25% of the shares subject to the option vest on August 1, 2023; (ii) 25% of the shares subject to the option vest on August 1, 2024; (iii) 25% of the shares subject to the option vest on August 1, 2025; and (iv) 25% of the shares subject to the option vest on August 1, 2026."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F2","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."}],"balance_after":250000,"derivative":{"exercise_price":1.14,"expiration_date":"2033-06-30","underlying":"Common Stock","underlying_shares":250000},"source":{"system":"sec-edgar","filing":"0001104659-23-078098","document":"tm2320488d5_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1644963/000110465923078098/tm2320488d5_4seq1.xml","form_type":"4"}},{"id":1837777,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":35267,"kind":"person","name":"ROSENWALD LINDSAY A MD","position":1,"cik":"0000941841","reported_name":"ROSENWALD LINDSAY A MD","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Employee stock option (right to buy)","published_at":"2023-07-05T20:08:48.000Z","date":"2023-06-30","kind":"grant","planned":false,"acquired":true,"shares":100000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in accordance with the following schedule: (i) one-third of the shares subject to the option vest on January 1, 2024; (ii) one-third of the shares subject to the option vest on January 1, 2025; and (iii) one-third of the shares subject to the option vest on January 1, 2026."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F2","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."}],"balance_after":100000,"derivative":{"exercise_price":1.14,"expiration_date":"2033-06-30","underlying":"Common Stock","underlying_shares":100000},"source":{"system":"sec-edgar","filing":"0001104659-23-078096","document":"tm2320488d4_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/941841/000110465923078096/tm2320488d4_4seq1.xml","form_type":"4"}},{"id":1835103,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":67711,"kind":"person","name":"Oltmans Curtis Gale","position":1,"cik":"0001714982","reported_name":"Oltmans Curtis Gale","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Employee stock option (right to buy)","published_at":"2023-07-05T20:07:52.000Z","date":"2023-06-30","kind":"grant","planned":false,"acquired":true,"shares":100000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in accordance with the following schedule: (i) one-third of the shares subject to the option vest on January 1, 2024; (ii) one-third of the shares subject to the option vest on January 1, 2025; and (iii) one-third of the shares subject to the option vest on January 1, 2026."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F2","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."}],"balance_after":100000,"derivative":{"exercise_price":1.14,"expiration_date":"2033-06-30","underlying":"Common Stock","underlying_shares":100000},"source":{"system":"sec-edgar","filing":"0001104659-23-078090","document":"tm2320488-2_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1644963/000110465923078090/tm2320488-2_4seq1.xml","form_type":"4"}},{"id":1835722,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":32768,"kind":"person","name":"Herskowitz Neil","position":1,"cik":"0001298246","reported_name":"Herskowitz Neil","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Employee stock option (right to buy)","published_at":"2023-07-05T20:07:28.000Z","date":"2023-06-30","kind":"grant","planned":false,"acquired":true,"shares":100000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in accordance with the following schedule: (i) one-third of the shares subject to the option vest on January 1, 2024; (ii) one-third of the shares subject to the option vest on January 1, 2025; and (iii) one-third of the shares subject to the option vest on January 1, 2026."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F2","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."}],"balance_after":100000,"derivative":{"exercise_price":1.14,"expiration_date":"2033-06-30","underlying":"Common Stock","underlying_shares":100000},"source":{"system":"sec-edgar","filing":"0001104659-23-078088","document":"tm2320488d1_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1298246/000110465923078088/tm2320488d1_4seq1.xml","form_type":"4"}},{"id":1836690,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":45701,"kind":"person","name":"Charles Faith L.","position":1,"cik":"0001853985","reported_name":"Charles Faith L.","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Employee stock option (right to buy)","published_at":"2023-07-05T16:10:00.000Z","date":"2023-06-30","kind":"grant","planned":false,"acquired":true,"shares":100000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in accordance with the following schedule: (i) one-third of the shares subject to the option vest on January 1, 2024; (ii) one-third of the shares subject to the option vest on January 1, 2025; and (iii) one-third of the shares subject to the option vest on January 1, 2026."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F2","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."}],"balance_after":100000,"derivative":{"exercise_price":1.14,"expiration_date":"2033-06-30","underlying":"Common Stock","underlying_shares":100000},"source":{"system":"sec-edgar","filing":"0001104659-23-078101","document":"tm2320488d6_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1853985/000110465923078101/tm2320488d6_4seq1.xml","form_type":"4"}},{"id":1837350,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":86264,"kind":"person","name":"KRANZLER JAY D","position":1,"cik":"0001055666","reported_name":"KRANZLER JAY D","relationship":{"director":true,"officer":false,"ten_percent_owner":false,"other":false}}],"security":"Employee stock option (right to buy)","published_at":"2023-07-05T16:08:39.000Z","date":"2023-06-30","kind":"grant","planned":false,"acquired":true,"shares":100000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in accordance with the following schedule: (i) one-third of the shares subject to the option vest on January 1, 2024; (ii) one-third of the shares subject to the option vest on January 1, 2025; and (iii) one-third of the shares subject to the option vest on January 1, 2026."},{"field":"derivative.underlying_shares","element":"underlyingSecurityShares","label":"F2","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."}],"balance_after":100000,"derivative":{"exercise_price":1.14,"expiration_date":"2033-06-30","underlying":"Common Stock","underlying_shares":100000},"source":{"system":"sec-edgar","filing":"0001104659-23-078094","document":"tm2320488-3_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1055666/000110465923078094/tm2320488-3_4seq1.xml","form_type":"4"}},{"id":1839910,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":87264,"kind":"person","name":"MacLean Alexandra","position":1,"cik":"0001940880","reported_name":"MacLean Alexandra","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"Chief Executive Officer"}}],"security":"Employee stock option (right to buy)","published_at":"2023-07-03T13:05:30.000Z","date":"2023-06-29","kind":"grant","planned":false,"acquired":true,"shares":800000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"The option vests in accordance with the following schedule: (i) 25% of the shares subject to the option vest on August 1, 2023; (ii) 25% of the shares subject to the option vest on August 1, 2024; (iii) 25% of the shares subject to the option vest on August 1, 2025; and (iv) 25% of the shares subject to the option vest on August 1, 2026."}],"balance_after":800000,"derivative":{"exercise_price":1.14,"expiration_date":"2033-06-29","underlying":"Common Stock","underlying_shares":800000},"source":{"system":"sec-edgar","filing":"0001104659-23-077528","document":"tm2320376-1_4seq1.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1940880/000110465923077528/tm2320376-1_4seq1.xml","form_type":"4"}},{"id":1927808,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":6822,"kind":"organization","name":"Fortress Biotech, Inc.","position":1,"cik":"0001429260","reported_name":"Fortress Biotech, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"COMMON STOCK, PAR VALUE $0.0001","published_at":"2023-04-04T20:08:05.000Z","date":"2023-03-31","kind":"grant","planned":false,"acquired":true,"shares":52419,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The Issuer is required to grant to the Reporting Person an equity fee in shares of the Issuer's Common Stock equal to 2.5% of the gross amount of any debt or equity financing consummated by the Issuer. These shares were granted by the Issuer to the Reporting Person following the closing of an equity financing."}],"balance_after":613980,"source":{"system":"sec-edgar","filing":"0001104659-23-041491","document":"tm2311448-2_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1429260/000110465923041491/tm2311448-2_4seq1.xml","form_type":"4"}},{"id":2067004,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":6822,"kind":"organization","name":"Fortress Biotech, Inc.","position":1,"cik":"0001429260","reported_name":"Fortress Biotech, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"COMMON STOCK, PAR VALUE $0.0001","published_at":"2023-01-04T22:49:03.000Z","date":"2023-01-03","kind":"grant","acquired":true,"shares":231316,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F2","text":"The Reporting Person is entitled to an annual dividend on its outstanding Class A Preferred Stock equal to 2.5% of the Issuer's fully diluted outstanding capitalization on December 31. These shares were granted by the Issuer to the Reporting Person for the 2022 annual dividend."},{"field":"shares","element":"transactionShares","label":"F4","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."}],"balance_after":561561,"source":{"system":"sec-edgar","filing":"0001104659-23-000998","document":"tm231707-1_4seq1.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1429260/000110465923000998/tm231707-1_4seq1.xml","form_type":"4"}},{"id":2067003,"issuer":{"id":8537,"kind":"organization","name":"AVENUE THERAPEUTICS, INC."},"owners":[{"id":6822,"kind":"organization","name":"Fortress Biotech, Inc.","position":1,"cik":"0001429260","reported_name":"Fortress Biotech, Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"COMMON STOCK, PAR VALUE $0.0001","published_at":"2023-01-04T22:49:03.000Z","date":"2022-12-31","kind":"grant","acquired":true,"shares":90909,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The Issuer is required to grant to the Reporting Person an equity fee in shares of the Issuer's Common Stock equal to 2.5% of the gross amount of any debt or equity financing consummated by the Issuer. These shares were granted by the Issuer to the Reporting Person following the closing of an equity financing."},{"field":"shares","element":"transactionShares","label":"F4","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). The amount of common stock reflected on this Form 4 has been adjusted to reflect the Reverse Stock Split."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F4","text":"Effective September 22, 2022, the Issuer effected a one-for-fifteen reverse stock split of its common stock (the \"Reverse Stock Split\"). 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