{"transactions":[{"id":4640516,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64702,"kind":"person","name":"Erbez Georgia","position":1,"cik":"0001557930","reported_name":"Erbez Georgia","relationship":{"director":false,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"See Remarks"}}],"security":"Common Stock","published_at":"2026-10-14T21:19:51.000Z","date":"2026-10-12","kind":"sale","planned":false,"acquired":false,"shares":6335,"price":1.3606,"value":8619.401,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold solely to satisfy tax or other government withholding obligations in connection with the vesting of shares subject to Restricted Stock Units (\"RSUs\") of the Issuer."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 7,707 restricted stock units."}],"balance_after":60475,"source":{"system":"sec-edgar","filing":"0001610717-26-000438","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1557930/000161071726000438/form4.xml","form_type":"4"}},{"id":4640514,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64703,"kind":"person","name":"MOORE ALISON","position":1,"cik":"0001754937","reported_name":"MOORE ALISON","relationship":{"director":true,"officer":true,"ten_percent_owner":false,"other":false,"officer_title":"President and CEO"}}],"security":"Common Stock","published_at":"2026-10-14T21:17:11.000Z","date":"2026-10-12","kind":"sale","planned":false,"acquired":false,"shares":6335,"price":1.3606,"value":8619.401,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold solely to satisfy tax or other government withholding obligations in connection with the vesting of shares subject to Restricted Stock Units (\"RSUs\") of the Issuer."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 119,582 restricted stock units."}],"balance_after":244171,"source":{"system":"sec-edgar","filing":"0001610717-26-000436","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1754937/000161071726000436/form4.xml","form_type":"4"}},{"id":731804,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36743,"kind":"person","name":"PARKER H STEWART","position":1,"cik":"0001217456","reported_name":"PARKER H STEWART","relationship":{"director":true}}],"security":"Stock Option (Right to Buy)","published_at":"2026-06-18T21:00:41.000Z","date":"2026-06-17","kind":"grant","planned":false,"acquired":true,"shares":66350,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vests and becomes exercisable with respect to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":66350,"derivative":{"exercise_price":2.48,"expiration_date":"2036-06-17","underlying":"Common Stock","underlying_shares":66350},"source":{"system":"sec-edgar","filing":"0001610717-26-000273","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000273/form4.xml","form_type":"4"}},{"id":731887,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36312,"kind":"person","name":"Collins Cynthia","position":1,"cik":"0001405692","reported_name":"Collins Cynthia","relationship":{"director":true}}],"security":"Stock Option (Right to Buy)","published_at":"2026-06-18T20:57:28.000Z","date":"2026-06-17","kind":"grant","planned":false,"acquired":true,"shares":66350,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vests and becomes exercisable with respect to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":66350,"derivative":{"exercise_price":2.48,"expiration_date":"2036-06-17","underlying":"Common Stock","underlying_shares":66350},"source":{"system":"sec-edgar","filing":"0001610717-26-000272","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1405692/000161071726000272/form4.xml","form_type":"4"}},{"id":731803,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36742,"kind":"person","name":"Richards Christos","position":1,"cik":"0001622055","reported_name":"Richards Christos","relationship":{"director":true}}],"security":"Stock Option (Right to Buy)","published_at":"2026-06-18T20:56:24.000Z","date":"2026-06-17","kind":"grant","planned":false,"acquired":true,"shares":66350,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vests and becomes exercisable with respect to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":66350,"derivative":{"exercise_price":2.48,"expiration_date":"2036-06-17","underlying":"Common Stock","underlying_shares":66350},"source":{"system":"sec-edgar","filing":"0001610717-26-000271","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000271/form4.xml","form_type":"4"}},{"id":731829,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36755,"kind":"person","name":"Smith David V","position":1,"cik":"0001229447","reported_name":"Smith David V","relationship":{"director":true}}],"security":"Stock Option (Right to Buy)","published_at":"2026-06-18T20:55:10.000Z","date":"2026-06-17","kind":"grant","planned":false,"acquired":true,"shares":66350,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vests and becomes exercisable with respect to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":66350,"derivative":{"exercise_price":2.48,"expiration_date":"2036-06-17","underlying":"Common Stock","underlying_shares":66350},"source":{"system":"sec-edgar","filing":"0001610717-26-000270","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1229447/000161071726000270/form4.xml","form_type":"4"}},{"id":731802,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36741,"kind":"person","name":"Singhvi Rahul","position":1,"cik":"0001322731","reported_name":"Singhvi Rahul","relationship":{"director":true}}],"security":"Stock Option (Right to Buy)","published_at":"2026-06-18T20:51:00.000Z","date":"2026-06-17","kind":"grant","planned":false,"acquired":true,"shares":66350,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vests and becomes exercisable with respect to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":66350,"derivative":{"exercise_price":2.48,"expiration_date":"2036-06-17","underlying":"Common Stock","underlying_shares":66350},"source":{"system":"sec-edgar","filing":"0001610717-26-000268","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000268/form4.xml","form_type":"4"}},{"id":731801,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36740,"kind":"person","name":"Martinborough Esther","position":1,"cik":"0001842383","reported_name":"Martinborough Esther","relationship":{"director":true}}],"security":"Stock Option (Right to Buy)","published_at":"2026-06-18T20:32:51.000Z","date":"2026-06-17","kind":"grant","planned":false,"acquired":true,"shares":66350,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vests and becomes exercisable with respect to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":66350,"derivative":{"exercise_price":2.48,"expiration_date":"2036-06-17","underlying":"Common Stock","underlying_shares":66350},"source":{"system":"sec-edgar","filing":"0001610717-26-000262","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000262/form4.xml","form_type":"4"}},{"id":731800,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36739,"kind":"person","name":"DILLY STEPHEN GEORGE","position":1,"cik":"0001389147","reported_name":"DILLY STEPHEN GEORGE","relationship":{"director":true}}],"security":"Stock Option (Right to Buy)","published_at":"2026-06-18T20:06:40.000Z","date":"2026-06-17","kind":"grant","planned":false,"acquired":true,"shares":66350,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vests and becomes exercisable with respect to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":66350,"derivative":{"exercise_price":2.48,"expiration_date":"2036-06-17","underlying":"Common Stock","underlying_shares":66350},"source":{"system":"sec-edgar","filing":"0001610717-26-000240","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000240/form4.xml","form_type":"4"}},{"id":732431,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36888,"kind":"person","name":"De Vre Raymond","position":1,"cik":"0002043287","reported_name":"De Vre Raymond","relationship":{"director":true}}],"security":"Stock Option (Right to Buy)","published_at":"2026-06-18T20:05:27.000Z","date":"2026-06-17","kind":"grant","planned":false,"acquired":true,"shares":66350,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vests and becomes exercisable with respect to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":66350,"derivative":{"exercise_price":2.48,"expiration_date":"2036-06-17","underlying":"Common Stock","underlying_shares":66350},"source":{"system":"sec-edgar","filing":"0001610717-26-000239","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/2043287/000161071726000239/form4.xml","form_type":"4"}},{"id":742003,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36888,"kind":"person","name":"De Vre Raymond","position":1,"cik":"0002043287","reported_name":"De Vre Raymond","relationship":{"director":true}}],"security":"Common Stock","published_at":"2026-06-12T00:19:27.000Z","date":"2026-06-11","kind":"sale","planned":false,"acquired":false,"shares":2605,"price":2.37,"value":6173.85,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported on this Form 4 was effected to cover tax liability incurred due to the vesting and release of Restricted Stock Units (\"RSUs\") held by the Reporting Person."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 31,897 RSUs."}],"balance_after":84811,"source":{"system":"sec-edgar","filing":"0001610717-26-000215","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/2043287/000161071726000215/form4.xml","form_type":"4"}},{"id":881692,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64704,"kind":"person","name":"Lutz Stefan","position":1,"cik":"0002094828","reported_name":"Lutz Stefan","relationship":{"officer":true,"officer_title":"Chief Scientific Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2026-02-26T00:54:29.000Z","date":"2026-02-23","kind":"grant","planned":false,"acquired":true,"shares":316100,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"This option vests and becomes exercisable with respect to 25% of the shares subject thereto on the first anniversary of the grant date, and with respect to 1/48th of the original number of shares subject thereto on each monthly anniversary thereafter, subject to the Reporting Person's continued employment through the applicable vesting dates."}],"balance_after":316100,"derivative":{"exercise_price":1.07,"expiration_date":"2036-02-23","underlying":"Common Stock","underlying_shares":316100},"source":{"system":"sec-edgar","filing":"0001610717-26-000073","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000073/form4.xml","form_type":"4"}},{"id":881691,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64704,"kind":"person","name":"Lutz Stefan","position":1,"cik":"0002094828","reported_name":"Lutz Stefan","relationship":{"officer":true,"officer_title":"Chief Scientific Officer"}}],"security":"Common Stock","published_at":"2026-02-26T00:54:29.000Z","date":"2026-02-24","kind":"sale","planned":false,"acquired":false,"shares":5862,"price":1.1329,"value":6641.0598,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold solely to satisfy tax or other government withholding obligations in connection with the vesting of shares subject to Restricted Stock Units (\"RSUs\") of the Issuer."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 23,299 RSUs."}],"balance_after":130421,"source":{"system":"sec-edgar","filing":"0001610717-26-000073","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000073/form4.xml","form_type":"4"}},{"id":881690,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64703,"kind":"person","name":"MOORE ALISON","position":1,"cik":"0001754937","reported_name":"MOORE ALISON","relationship":{"director":true,"officer":true,"officer_title":"President and CEO"}}],"security":"Stock Option (Right to Buy)","published_at":"2026-02-26T00:53:47.000Z","date":"2026-02-23","kind":"grant","planned":false,"acquired":true,"shares":993000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vests and becomes exercisable with respect to 25% of the shares subject thereto on the first anniversary of the grant date, and with respect to 1/48th of the original number of shares subject thereto on each monthly anniversary thereafter, subject to the Reporting Person's continued employment through the applicable vesting dates."}],"balance_after":993000,"derivative":{"exercise_price":1.07,"expiration_date":"2036-02-23","underlying":"Common Stock","underlying_shares":993000},"source":{"system":"sec-edgar","filing":"0001610717-26-000072","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000072/form4.xml","form_type":"4"}},{"id":881688,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64702,"kind":"person","name":"Erbez Georgia","position":1,"cik":"0001557930","reported_name":"Erbez Georgia","relationship":{"officer":true,"officer_title":"See Remarks"}}],"security":"Stock Option (Right to Buy)","published_at":"2026-02-26T00:53:07.000Z","date":"2026-02-23","kind":"grant","planned":false,"acquired":true,"shares":316100,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F1","text":"This option vests and becomes exercisable with respect to 25% of the shares subject thereto on the first anniversary of the grant date, and with respect to 1/48th of the original number of shares subject thereto on each monthly anniversary thereafter, subject to the Reporting Person's continued employment through the applicable vesting dates."}],"balance_after":316100,"derivative":{"exercise_price":1.07,"expiration_date":"2036-02-23","underlying":"Common Stock","underlying_shares":316100},"source":{"system":"sec-edgar","filing":"0001610717-26-000071","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000071/form4.xml","form_type":"4"}},{"id":914232,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64704,"kind":"person","name":"Lutz Stefan","position":1,"cik":"0002094828","reported_name":"Lutz Stefan","relationship":{"officer":true,"officer_title":"Chief Scientific Officer"}}],"security":"Common Stock","published_at":"2026-02-09T21:07:41.000Z","date":"2026-02-06","kind":"sale","planned":false,"acquired":false,"shares":2492,"price":1.3071,"value":3257.2932,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold solely to satisfy tax or other government withholding obligations in connection with the vesting of shares subject to Restricted Stock Units (\"RSUs\") of the Issuer."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 35,799 restricted stock units."}],"balance_after":136283,"source":{"system":"sec-edgar","filing":"0001610717-26-000047","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000047/form4.xml","form_type":"4"}},{"id":914231,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64702,"kind":"person","name":"Erbez Georgia","position":1,"cik":"0001557930","reported_name":"Erbez Georgia","relationship":{"officer":true,"officer_title":"See Remarks"}}],"security":"Common Stock","published_at":"2026-02-09T21:07:00.000Z","date":"2026-02-06","kind":"sale","planned":false,"acquired":false,"shares":3826,"price":1.3071,"value":5000.9646,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold solely to satisfy tax or other government withholding obligations in connection with the vesting of shares subject to Restricted Stock Units (\"RSUs\") of the Issuer."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 24,374 restricted stock units."}],"balance_after":66810,"source":{"system":"sec-edgar","filing":"0001610717-26-000046","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000046/form4.xml","form_type":"4"}},{"id":914230,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64703,"kind":"person","name":"MOORE ALISON","position":1,"cik":"0001754937","reported_name":"MOORE ALISON","relationship":{"director":true,"officer":true,"officer_title":"President and CEO"}}],"security":"Common Stock","published_at":"2026-02-09T21:06:10.000Z","date":"2026-02-06","kind":"sale","planned":false,"acquired":false,"shares":3826,"price":1.3071,"value":5000.9646,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold solely to satisfy tax or other government withholding obligations in connection with the vesting of shares subject to Restricted Stock Units (\"RSUs\") of the Issuer."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 136,249 restricted stock units."}],"balance_after":250506,"source":{"system":"sec-edgar","filing":"0001610717-26-000045","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000045/form4.xml","form_type":"4"}},{"id":943107,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64704,"kind":"person","name":"Lutz Stefan","position":1,"cik":"0002094828","reported_name":"Lutz Stefan","relationship":{"officer":true,"officer_title":"CSO"}}],"security":"Common Stock","published_at":"2026-01-08T23:51:48.000Z","date":"2026-01-07","kind":"sale","planned":false,"acquired":false,"shares":4685,"price":1.6968,"value":7949.508,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported on this Form 4 was effected to cover tax liability incurred due to the vesting and release of Restricted Stock Units held by the Reporting Person."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 41,633 restricted stock units."}],"balance_after":138775,"source":{"system":"sec-edgar","filing":"0001610717-26-000007","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071726000007/form4.xml","form_type":"4"}},{"id":969126,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-15T11:06:27.000Z","date":"2025-12-01","kind":"sale","planned":false,"acquired":false,"shares":8533,"price":1.6675,"value":14228.7775,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":179989,"source":{"system":"sec-edgar","filing":"0001493152-25-027633","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225027633/ownership.xml","form_type":"4/A","original_submission_date":"2025-12-01"}},{"id":969125,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-15T11:06:27.000Z","date":"2025-12-01","kind":"sale","planned":false,"acquired":false,"shares":245000,"price":1.6675,"value":408537.5,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9955000,"source":{"system":"sec-edgar","filing":"0001493152-25-027633","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225027633/ownership.xml","form_type":"4/A","original_submission_date":"2025-12-01"}},{"id":969124,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-15T11:06:27.000Z","date":"2025-11-28","kind":"sale","planned":false,"acquired":false,"shares":2490,"price":1.75,"value":4357.5,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":188522,"source":{"system":"sec-edgar","filing":"0001493152-25-027633","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225027633/ownership.xml","form_type":"4/A","original_submission_date":"2025-12-01"}},{"id":969123,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-15T11:06:27.000Z","date":"2025-11-28","kind":"sale","planned":false,"acquired":false,"shares":105000,"price":1.75,"value":183750.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":10200000,"source":{"system":"sec-edgar","filing":"0001493152-25-027633","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225027633/ownership.xml","form_type":"4/A","original_submission_date":"2025-12-01"}},{"id":969122,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-15T11:06:27.000Z","date":"2025-11-26","kind":"sale","planned":false,"acquired":false,"shares":5000,"price":1.7413,"value":8706.5,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7316 - $1.75699 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":191012,"source":{"system":"sec-edgar","filing":"0001493152-25-027633","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225027633/ownership.xml","form_type":"4/A","original_submission_date":"2025-12-01"}},{"id":969121,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-15T11:06:27.000Z","date":"2025-11-26","kind":"sale","planned":false,"acquired":false,"shares":148318,"price":1.7413,"value":258266.1334,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7316 - $1.75699 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":10305000,"source":{"system":"sec-edgar","filing":"0001493152-25-027633","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225027633/ownership.xml","form_type":"4/A","original_submission_date":"2025-12-01"}},{"id":969132,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-15T11:06:25.000Z","date":"2025-11-11","kind":"sale","planned":false,"acquired":false,"shares":13211,"price":1.7994,"value":23771.8734,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.68 - $1.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70 - $1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7696 - $1.81 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":223461,"source":{"system":"sec-edgar","filing":"0001493152-25-027632","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225027632/ownership.xml","form_type":"4/A","original_submission_date":"2025-11-12"}},{"id":969131,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-15T11:06:25.000Z","date":"2025-11-11","kind":"sale","planned":false,"acquired":false,"shares":535000,"price":1.7994,"value":962679.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.68 - $1.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70 - $1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7696 - $1.81 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":11508318,"source":{"system":"sec-edgar","filing":"0001493152-25-027632","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225027632/ownership.xml","form_type":"4/A","original_submission_date":"2025-11-12"}},{"id":969130,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-15T11:06:25.000Z","date":"2025-11-10","kind":"sale","planned":false,"acquired":false,"shares":3318,"price":1.7347,"value":5755.7346,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.68 - $1.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70 - $1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7696 - $1.81 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":236682,"source":{"system":"sec-edgar","filing":"0001493152-25-027632","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225027632/ownership.xml","form_type":"4/A","original_submission_date":"2025-11-12"}},{"id":969129,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-15T11:06:25.000Z","date":"2025-11-10","kind":"sale","planned":false,"acquired":false,"shares":205000,"price":1.7347,"value":355613.5,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.68 - $1.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70 - $1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7696 - $1.81 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12043318,"source":{"system":"sec-edgar","filing":"0001493152-25-027632","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225027632/ownership.xml","form_type":"4/A","original_submission_date":"2025-11-12"}},{"id":969128,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-15T11:06:25.000Z","date":"2025-11-07","kind":"sale","planned":false,"acquired":false,"shares":10000,"price":1.6968,"value":16968.0,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.68 - $1.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70 - $1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7696 - $1.81 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":240000,"source":{"system":"sec-edgar","filing":"0001493152-25-027632","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225027632/ownership.xml","form_type":"4/A","original_submission_date":"2025-11-12"}},{"id":969127,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-15T11:06:25.000Z","date":"2025-11-07","kind":"sale","planned":false,"acquired":false,"shares":296682,"price":1.6968,"value":503410.0176,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.68 - $1.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70 - $1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7696 - $1.81 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12248318,"source":{"system":"sec-edgar","filing":"0001493152-25-027632","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225027632/ownership.xml","form_type":"4/A","original_submission_date":"2025-11-12"}},{"id":984940,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-01T22:41:43.000Z","date":"2025-12-01","kind":"sale","planned":false,"acquired":false,"shares":8533,"price":1.6675,"value":14228.7775,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":179989,"source":{"system":"sec-edgar","filing":"0001493152-25-025624","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225025624/ownership.xml","form_type":"4"}},{"id":984939,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-01T22:41:43.000Z","date":"2025-12-01","kind":"sale","planned":false,"acquired":false,"shares":245000,"price":1.6675,"value":408537.5,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.65 - $1.7101 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9955000,"source":{"system":"sec-edgar","filing":"0001493152-25-025624","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225025624/ownership.xml","form_type":"4"}},{"id":984938,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-01T22:41:43.000Z","date":"2025-11-28","kind":"sale","planned":false,"acquired":false,"shares":2490,"price":1.75,"value":4357.5,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":188522,"source":{"system":"sec-edgar","filing":"0001493152-25-025624","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225025624/ownership.xml","form_type":"4"}},{"id":984937,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-01T22:41:43.000Z","date":"2025-11-28","kind":"sale","planned":false,"acquired":false,"shares":105000,"price":1.75,"value":183750.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.73 - $1.7715 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":10200000,"source":{"system":"sec-edgar","filing":"0001493152-25-025624","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225025624/ownership.xml","form_type":"4"}},{"id":984936,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-01T22:41:43.000Z","date":"2025-11-26","kind":"sale","planned":false,"acquired":false,"shares":5000,"price":1.7413,"value":8706.5,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7316 - $1.75699 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":191012,"source":{"system":"sec-edgar","filing":"0001493152-25-025624","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225025624/ownership.xml","form_type":"4"}},{"id":984935,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-12-01T22:41:43.000Z","date":"2025-11-26","kind":"sale","planned":false,"acquired":true,"shares":148318,"price":1.7413,"value":258266.1334,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7316 - $1.75699 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":10305000,"source":{"system":"sec-edgar","filing":"0001493152-25-025624","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225025624/ownership.xml","form_type":"4"}},{"id":988525,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":72578,"kind":"person","name":"WOLF DENNIS P","position":1,"cik":"0001227560","reported_name":"WOLF DENNIS P","relationship":{"director":true}}],"security":"Common Stock","published_at":"2025-11-25T16:18:50.000Z","date":"2025-11-21","kind":"sale","planned":false,"acquired":false,"shares":8952,"price":1.5626,"value":13988.3952,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"This transaction was executed in multiple trades in prices ranging from $1.55 to $1.615, inclusive. The price reported in Column 4 above reflects the weighted average sale price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares sold at each respective price within the range set forth in this footnote."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 40,983 restricted stock units."}],"balance_after":138951,"source":{"system":"sec-edgar","filing":"0001610717-25-000386","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1227560/000161071725000386/form4.xml","form_type":"4"}},{"id":997616,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64703,"kind":"person","name":"MOORE ALISON","position":1,"cik":"0001754937","reported_name":"MOORE ALISON","relationship":{"officer":true,"officer_title":"President and CEO"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-11-17T22:11:27.000Z","date":"2025-11-13","kind":"grant","planned":false,"acquired":true,"shares":500000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F3","text":"This option vests and becomes exercisable with respect to 25% of the shares subject thereto on the first anniversary of the grant date, and with respect to 1/48th of the original number of shares subject thereto on each monthly anniversary thereafter, subject to the Reporting Person's continued employment through the applicable vesting dates."}],"balance_after":500000,"derivative":{"exercise_price":1.63,"expiration_date":"2035-11-13","underlying":"Common Stock","underlying_shares":500000},"source":{"system":"sec-edgar","filing":"0001610717-25-000382","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071725000382/form4.xml","form_type":"4"}},{"id":997615,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64703,"kind":"person","name":"MOORE ALISON","position":1,"cik":"0001754937","reported_name":"MOORE ALISON","relationship":{"officer":true,"officer_title":"President and CEO"}}],"security":"Common Stock","published_at":"2025-11-17T22:11:27.000Z","date":"2025-11-13","kind":"grant","planned":false,"acquired":true,"shares":85000,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"These restricted stock units vest as to 1/3rd of the shares on each annual anniversary of the grant date, subject to the Reporting Person's continued employment through the applicable vesting dates."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 145,208 restricted stock units."}],"balance_after":254332,"source":{"system":"sec-edgar","filing":"0001610717-25-000382","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071725000382/form4.xml","form_type":"4"}},{"id":998756,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-11-14T21:15:05.000Z","date":"2025-11-12","kind":"sale","planned":false,"acquired":false,"shares":165000,"price":1.962,"value":323730.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.9005 - $1.9905 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.935 - $2.0035 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":10453318,"source":{"system":"sec-edgar","filing":"0001493152-25-023486","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225023486/ownership.xml","form_type":"4"}},{"id":998755,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-11-14T21:15:05.000Z","date":"2025-11-12","kind":"sale","planned":false,"acquired":false,"shares":27459,"price":1.9372,"value":53193.5748,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.9005 - $1.9905 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":196012,"source":{"system":"sec-edgar","filing":"0001493152-25-023486","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225023486/ownership.xml","form_type":"4"}},{"id":998754,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-11-14T21:15:05.000Z","date":"2025-11-12","kind":"sale","planned":false,"acquired":true,"shares":890000,"price":1.9372,"value":1724108.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.9005 - $1.9905 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.935 - $2.0035 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":10618318,"source":{"system":"sec-edgar","filing":"0001493152-25-023486","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225023486/ownership.xml","form_type":"4"}},{"id":1000577,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36888,"kind":"person","name":"De Vre Raymond","position":1,"cik":"0002043287","reported_name":"De Vre Raymond","relationship":{"director":true}}],"security":"Common Stock","published_at":"2025-11-13T21:16:31.000Z","date":"2025-11-11","kind":"sale","planned":false,"acquired":false,"shares":1413,"price":1.74,"value":2458.62,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The sale reported on this Form 4 was effected to cover tax liability incurred due to the vesting and release of Restricted Stock Units held by the Reporting Person."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 72,880 restricted stock units."}],"balance_after":87416,"source":{"system":"sec-edgar","filing":"0001610717-25-000376","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/2043287/000161071725000376/form4.xml","form_type":"4"}},{"id":1001761,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36739,"kind":"person","name":"DILLY STEPHEN GEORGE","position":1,"cik":"0001389147","reported_name":"DILLY STEPHEN GEORGE","relationship":{"director":true}}],"security":"Common Stock","published_at":"2025-11-12T21:31:29.000Z","date":"2025-11-11","kind":"grant","planned":false,"acquired":true,"shares":50000,"price":1.8473,"value":92365.0,"ownership":{"direct":true},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F1","text":"This transaction was executed in multiple trades in prices ranging from $1.7550 to $1.90, inclusive. The price reported in Column 4 above reflects the weighted average purchase price. The Reporting Person hereby undertakes to provide to the Securities and Exchange Commission staff, the Issuer, or a security holder of the Issuer, upon request, full information regarding the number of shares purchased at each respective price within the range set forth in this footnote."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 2,000 shares acquired under the issuer's Employee Stock Purchase Plan on May 10, 2025."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F3","text":"Includes 2,000 shares acquired under the issuer's Employee Stock Purchase Plan on November 10, 2025."}],"balance_after":727053,"source":{"system":"sec-edgar","filing":"0001610717-25-000374","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071725000374/form4.xml","form_type":"4"}},{"id":1001767,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-11-12T21:05:17.000Z","date":"2025-11-11","kind":"sale","planned":false,"acquired":false,"shares":13211,"price":1.7994,"value":23771.8734,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.68 - $1.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70 - $1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7696 - $1.81 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":223461,"source":{"system":"sec-edgar","filing":"0001493152-25-021897","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":6,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225021897/ownership.xml","form_type":"4"}},{"id":1001766,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-11-12T21:05:17.000Z","date":"2025-11-11","kind":"sale","planned":false,"acquired":false,"shares":535000,"price":1.7994,"value":962679.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.68 - $1.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70 - $1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7696 - $1.81 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":11508318,"source":{"system":"sec-edgar","filing":"0001493152-25-021897","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":5,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225021897/ownership.xml","form_type":"4"}},{"id":1001765,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-11-12T21:05:17.000Z","date":"2025-11-10","kind":"sale","planned":false,"acquired":false,"shares":3318,"price":1.7347,"value":5755.7346,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.68 - $1.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70 - $1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7696 - $1.81 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":236682,"source":{"system":"sec-edgar","filing":"0001493152-25-021897","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":4,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225021897/ownership.xml","form_type":"4"}},{"id":1001764,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-11-12T21:05:17.000Z","date":"2025-11-10","kind":"sale","planned":false,"acquired":false,"shares":205000,"price":1.7347,"value":355613.5,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.68 - $1.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70 - $1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7696 - $1.81 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12043318,"source":{"system":"sec-edgar","filing":"0001493152-25-021897","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225021897/ownership.xml","form_type":"4"}},{"id":1001763,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-11-12T21:05:17.000Z","date":"2025-11-07","kind":"sale","planned":false,"acquired":false,"shares":10000,"price":1.6968,"value":16968.0,"ownership":{"direct":false,"nature":"By Managed Account"},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F2","text":"Securities owned by a separately managed account (the \"Managed Account\"). As the portfolio manager of the Managed Account, Opaleye may be deemed to beneficially own the securities owned directly by the Managed Account."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.68 - $1.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70 - $1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7696 - $1.81 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":240000,"source":{"system":"sec-edgar","filing":"0001493152-25-021897","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225021897/ownership.xml","form_type":"4"}},{"id":1001762,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-11-12T21:05:17.000Z","date":"2025-11-07","kind":"sale","planned":false,"acquired":true,"shares":296682,"price":1.6968,"value":503410.0176,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.68 - $1.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.70 - $1.75 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were sold in multiple transactions at prices ranging from $1.7696 - $1.81 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12248318,"source":{"system":"sec-edgar","filing":"0001493152-25-021897","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225021897/ownership.xml","form_type":"4"}},{"id":1018303,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64703,"kind":"person","name":"MOORE ALISON","position":1,"cik":"0001754937","reported_name":"MOORE ALISON","relationship":{"officer":true,"officer_title":"Chief Technical Officer"}}],"security":"Common Stock","published_at":"2025-10-15T21:14:23.000Z","date":"2025-10-13","kind":"sale","planned":false,"acquired":false,"shares":6239,"price":2.5051,"value":15629.3189,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold solely to satisfy tax or other government withholding obligations in connection with the vesting of shares subject to Restricted Stock Units (\"RSUs\") of the Issuer."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 33,333 restricted stock units."}],"balance_after":169332,"source":{"system":"sec-edgar","filing":"0001610717-25-000363","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071725000363/form4.xml","form_type":"4"}},{"id":1018302,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64702,"kind":"person","name":"Erbez Georgia","position":1,"cik":"0001557930","reported_name":"Erbez Georgia","relationship":{"officer":true,"officer_title":"Chief Financial Officer"}}],"security":"Common Stock","published_at":"2025-10-15T21:13:37.000Z","date":"2025-10-13","kind":"sale","planned":false,"acquired":false,"shares":6239,"price":2.505,"value":15628.695,"ownership":{"direct":true},"footnotes":[{"field":"kind","element":"transactionCoding","label":"F1","text":"The shares were sold solely to satisfy tax or other government withholding obligations in connection with the vesting of shares subject to Restricted Stock Units (\"RSUs\") of the Issuer."},{"field":"balance_after","element":"sharesOwnedFollowingTransaction","label":"F2","text":"Includes 33,333 restricted stock units."}],"balance_after":70636,"source":{"system":"sec-edgar","filing":"0001610717-25-000362","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000161071725000362/form4.xml","form_type":"4"}},{"id":1076129,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-08-04T20:38:06.000Z","date":"2025-08-04","kind":"purchase","planned":false,"acquired":true,"shares":780,"price":2.835,"value":2211.3,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12545000,"source":{"system":"sec-edgar","filing":"0001641172-25-022060","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225022060/ownership.xml","form_type":"4"}},{"id":1076128,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-08-04T20:38:06.000Z","date":"2025-07-31","kind":"purchase","planned":false,"acquired":true,"shares":84220,"price":2.68,"value":225709.6,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12544220,"source":{"system":"sec-edgar","filing":"0001641172-25-022060","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225022060/ownership.xml","form_type":"4"}},{"id":1078288,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-07-31T20:05:07.000Z","date":"2025-07-30","kind":"purchase","planned":false,"acquired":true,"shares":1578,"price":2.795,"value":4410.51,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12460000,"source":{"system":"sec-edgar","filing":"0001641172-25-021727","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225021727/ownership.xml","form_type":"4"}},{"id":1078287,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-07-31T20:05:07.000Z","date":"2025-07-29","kind":"purchase","planned":false,"acquired":true,"shares":8422,"price":2.82,"value":23750.04,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12458422,"source":{"system":"sec-edgar","filing":"0001641172-25-021727","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225021727/ownership.xml","form_type":"4"}},{"id":1083294,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-07-22T20:05:11.000Z","date":"2025-07-18","kind":"purchase","planned":false,"acquired":true,"shares":100000,"price":2.82,"value":282000.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12450000,"source":{"system":"sec-edgar","filing":"0001641172-25-020566","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225020566/ownership.xml","form_type":"4"}},{"id":1097665,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-07-01T20:05:08.000Z","date":"2025-06-27","kind":"purchase","planned":false,"acquired":true,"shares":100000,"price":2.39,"value":239000.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12350000,"source":{"system":"sec-edgar","filing":"0001641172-25-017361","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225017361/ownership.xml","form_type":"4"}},{"id":1109618,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-06-16T20:59:00.000Z","date":"2025-06-16","kind":"purchase","planned":false,"acquired":true,"shares":50898,"price":2.24,"value":114011.52,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12250000,"source":{"system":"sec-edgar","filing":"0001641172-25-015281","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225015281/ownership.xml","form_type":"4"}},{"id":1109617,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-06-16T20:59:00.000Z","date":"2025-06-13","kind":"purchase","planned":false,"acquired":true,"shares":99102,"price":2.23,"value":220997.46,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12199102,"source":{"system":"sec-edgar","filing":"0001641172-25-015281","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225015281/ownership.xml","form_type":"4"}},{"id":1109616,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-06-16T20:59:00.000Z","date":"2025-06-12","kind":"purchase","planned":false,"acquired":true,"shares":100000,"price":2.25,"value":225000.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12100000,"source":{"system":"sec-edgar","filing":"0001641172-25-015281","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225015281/ownership.xml","form_type":"4"}},{"id":1113096,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36755,"kind":"person","name":"Smith David V","position":1,"cik":"0001229447","reported_name":"Smith David V","relationship":{"director":true}}],"security":"Common Stock","published_at":"2025-06-12T23:30:24.000Z","date":"2025-06-10","kind":"grant","planned":false,"acquired":true,"shares":40983,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The restricted stock units vest as to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":105705,"source":{"system":"sec-edgar","filing":"0000905148-25-002134","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1229447/000090514825002134/form4.xml","form_type":"4"}},{"id":1113061,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36741,"kind":"person","name":"Singhvi Rahul","position":1,"cik":"0001322731","reported_name":"Singhvi Rahul","relationship":{"director":true}}],"security":"Common Stock","published_at":"2025-06-12T23:30:12.000Z","date":"2025-06-10","kind":"grant","planned":false,"acquired":true,"shares":40983,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The restricted stock units vest as to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":137052,"source":{"system":"sec-edgar","filing":"0000905148-25-002133","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000090514825002133/form4.xml","form_type":"4"}},{"id":1113059,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36742,"kind":"person","name":"Richards Christos","position":1,"cik":"0001622055","reported_name":"Richards Christos","relationship":{"director":true}}],"security":"Common Stock","published_at":"2025-06-12T23:29:55.000Z","date":"2025-06-10","kind":"grant","planned":false,"acquired":true,"shares":40983,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The restricted stock units vest as to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":85133,"source":{"system":"sec-edgar","filing":"0000905148-25-002132","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000090514825002132/form4.xml","form_type":"4"}},{"id":1113060,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36743,"kind":"person","name":"PARKER H STEWART","position":1,"cik":"0001217456","reported_name":"PARKER H STEWART","relationship":{"director":true}}],"security":"Common Stock","published_at":"2025-06-12T23:29:43.000Z","date":"2025-06-10","kind":"grant","planned":false,"acquired":true,"shares":40983,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The restricted stock units vest as to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":143583,"source":{"system":"sec-edgar","filing":"0000905148-25-002131","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000090514825002131/form4.xml","form_type":"4"}},{"id":1113058,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36740,"kind":"person","name":"Martinborough Esther","position":1,"cik":"0001842383","reported_name":"Martinborough Esther","relationship":{"director":true}}],"security":"Common Stock","published_at":"2025-06-12T23:29:28.000Z","date":"2025-06-10","kind":"grant","planned":false,"acquired":true,"shares":40983,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The restricted stock units vest as to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":129036,"source":{"system":"sec-edgar","filing":"0000905148-25-002130","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000090514825002130/form4.xml","form_type":"4"}},{"id":1113827,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36888,"kind":"person","name":"De Vre Raymond","position":1,"cik":"0002043287","reported_name":"De Vre Raymond","relationship":{"director":true}}],"security":"Common Stock","published_at":"2025-06-12T23:29:10.000Z","date":"2025-06-10","kind":"grant","planned":false,"acquired":true,"shares":40983,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The restricted stock units vest as to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":88829,"source":{"system":"sec-edgar","filing":"0000905148-25-002129","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/2043287/000090514825002129/form4.xml","form_type":"4"}},{"id":1113180,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36312,"kind":"person","name":"Collins Cynthia","position":1,"cik":"0001405692","reported_name":"Collins Cynthia","relationship":{"director":true}}],"security":"Common Stock","published_at":"2025-06-12T23:28:56.000Z","date":"2025-06-10","kind":"grant","planned":false,"acquired":true,"shares":40983,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The restricted stock units vest as to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":112157,"source":{"system":"sec-edgar","filing":"0000905148-25-002128","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1405692/000090514825002128/form4.xml","form_type":"4"}},{"id":1113093,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":72578,"kind":"person","name":"WOLF DENNIS P","position":1,"cik":"0001227560","reported_name":"WOLF DENNIS P","relationship":{"director":true}}],"security":"Common Stock","published_at":"2025-06-12T19:30:36.000Z","date":"2025-06-10","kind":"grant","planned":false,"acquired":true,"shares":40983,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"The restricted stock units vest as to all of the shares subject to the award on the earlier of the first anniversary of the date of grant or the next annual stockholder meeting, subject to the director's continued service to the Company on such vesting date."}],"balance_after":147903,"source":{"system":"sec-edgar","filing":"0000905148-25-002135","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1227560/000090514825002135/form4.xml","form_type":"4"}},{"id":1131663,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-05-28T20:05:23.000Z","date":"2025-05-28","kind":"purchase","planned":false,"acquired":true,"shares":5000,"price":2.36,"value":11800.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":12000000,"source":{"system":"sec-edgar","filing":"0001641172-25-012682","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225012682/ownership.xml","form_type":"4"}},{"id":1131662,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-05-28T20:05:23.000Z","date":"2025-05-23","kind":"purchase","planned":false,"acquired":true,"shares":2320000,"price":2.36,"value":5475200.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":11995000,"source":{"system":"sec-edgar","filing":"0001641172-25-012682","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225012682/ownership.xml","form_type":"4"}},{"id":1160895,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-05-02T20:05:14.000Z","date":"2025-05-01","kind":"purchase","planned":false,"acquired":true,"shares":20000,"price":2.3218,"value":46436.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.3074 - $2.324 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9675000,"source":{"system":"sec-edgar","filing":"0001641172-25-008335","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225008335/ownership.xml","form_type":"4"}},{"id":1160894,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-05-02T20:05:14.000Z","date":"2025-04-30","kind":"purchase","planned":false,"acquired":true,"shares":25000,"price":2.3064,"value":57660.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.2503 - $2.3294 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9655000,"source":{"system":"sec-edgar","filing":"0001641172-25-008335","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225008335/ownership.xml","form_type":"4"}},{"id":1163819,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-04-29T20:05:11.000Z","date":"2025-04-25","kind":"purchase","planned":false,"acquired":true,"shares":25000,"price":2.2366,"value":55915.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.215 - $2.2469 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9630000,"source":{"system":"sec-edgar","filing":"0001641172-25-006646","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225006646/ownership.xml","form_type":"4"}},{"id":1169583,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-04-17T22:07:35.000Z","date":"2025-04-17","kind":"purchase","planned":false,"acquired":true,"shares":45000,"price":2.0925,"value":94162.5,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.065 - $2.1163 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9605000,"source":{"system":"sec-edgar","filing":"0001641172-25-005318","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225005318/ownership.xml","form_type":"4"}},{"id":1169582,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-04-17T22:07:35.000Z","date":"2025-04-16","kind":"purchase","planned":false,"acquired":true,"shares":70000,"price":2.127,"value":148890.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.0855 - $2.2255 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9560000,"source":{"system":"sec-edgar","filing":"0001641172-25-005318","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225005318/ownership.xml","form_type":"4"}},{"id":1169581,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-04-17T22:07:35.000Z","date":"2025-04-15","kind":"purchase","planned":false,"acquired":true,"shares":25000,"price":2.2288,"value":55720.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.215 - $2.2573 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9490000,"source":{"system":"sec-edgar","filing":"0001641172-25-005318","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225005318/ownership.xml","form_type":"4"}},{"id":1174597,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-04-09T20:05:11.000Z","date":"2025-04-08","kind":"purchase","planned":false,"acquired":true,"shares":100000,"price":1.9838,"value":198380.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $1.9751 - $1.9899 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9465000,"source":{"system":"sec-edgar","filing":"0001641172-25-003402","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225003402/ownership.xml","form_type":"4"}},{"id":1179102,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-04-03T23:39:54.000Z","date":"2025-04-03","kind":"purchase","planned":false,"acquired":true,"shares":75000,"price":2.3032,"value":172740.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F5","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.3552 - $2.2469 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9365000,"source":{"system":"sec-edgar","filing":"0001641172-25-002641","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225002641/ownership.xml","form_type":"4"}},{"id":1179101,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-04-03T23:39:54.000Z","date":"2025-04-02","kind":"purchase","planned":false,"acquired":true,"shares":5000,"price":2.4552,"value":12276.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.455 - $2.4552 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9290000,"source":{"system":"sec-edgar","filing":"0001641172-25-002641","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225002641/ownership.xml","form_type":"4"}},{"id":1179100,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-04-03T23:39:54.000Z","date":"2025-04-01","kind":"purchase","planned":false,"acquired":true,"shares":35000,"price":2.4792,"value":86772.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.465 - $2.50 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F6","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9285000,"source":{"system":"sec-edgar","filing":"0001641172-25-002641","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225002641/ownership.xml","form_type":"4"}},{"id":1186314,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":36312,"kind":"person","name":"Collins Cynthia","position":1,"cik":"0001405692","reported_name":"Collins Cynthia","relationship":{"director":true}}],"security":"Common Stock","published_at":"2025-04-01T16:39:38.000Z","date":"2025-03-28","kind":"grant","planned":false,"acquired":true,"shares":71174,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"These restricted stock units vest as to 1/3rd of the shares on each annual anniversary of the grant date, subject to the Reporting Person's continued service through the applicable vesting dates."}],"balance_after":71174,"source":{"system":"sec-edgar","filing":"0000905148-25-001032","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1405692/000090514825001032/form4.xml","form_type":"4"}},{"id":1193271,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-03-24T20:05:29.000Z","date":"2025-03-21","kind":"purchase","planned":false,"acquired":true,"shares":92923,"price":2.5426,"value":236266.0198,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.45 -$2.5785 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9250000,"source":{"system":"sec-edgar","filing":"0001641172-25-000277","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225000277/ownership.xml","form_type":"4"}},{"id":1193270,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-03-24T20:05:29.000Z","date":"2025-03-20","kind":"purchase","planned":false,"acquired":true,"shares":7.077,"price":2.5386,"value":17.9656722,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.538 - $2.5397 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9157077,"source":{"system":"sec-edgar","filing":"0001641172-25-000277","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000164117225000277/ownership.xml","form_type":"4"}},{"id":1205536,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-03-14T20:05:21.000Z","date":"2025-03-13","kind":"purchase","planned":false,"acquired":true,"shares":85000,"price":2.543,"value":216155.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.52 - $2.58 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9150000,"source":{"system":"sec-edgar","filing":"0001493152-25-010360","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225010360/ownership.xml","form_type":"4"}},{"id":1214787,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-03-10T21:16:35.000Z","date":"2025-03-06","kind":"purchase","planned":false,"acquired":true,"shares":100000,"price":2.6135,"value":261350.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.4784 - $2.71 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F3","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":9065000,"source":{"system":"sec-edgar","filing":"0001493152-25-009728","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225009728/ownership.xml","form_type":"4"}},{"id":1219255,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-03-06T21:51:53.000Z","date":"2025-03-05","kind":"purchase","planned":false,"acquired":true,"shares":10000,"price":2.6875,"value":26875.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.505 - $2.73 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":8965000,"source":{"system":"sec-edgar","filing":"0001493152-25-009407","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225009407/ownership.xml","form_type":"4"}},{"id":1219254,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-03-06T21:51:53.000Z","date":"2025-03-04","kind":"purchase","planned":false,"acquired":true,"shares":55000,"price":2.6436,"value":145398.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.5054 - $2.73 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":8955000,"source":{"system":"sec-edgar","filing":"0001493152-25-009407","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225009407/ownership.xml","form_type":"4"}},{"id":1227295,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-03-04T21:05:12.000Z","date":"2025-03-03","kind":"purchase","planned":false,"acquired":true,"shares":47351,"price":2.8123,"value":133165.2173,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.755 - $2.84 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":8900000,"source":{"system":"sec-edgar","filing":"0001493152-25-009039","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225009039/ownership.xml","form_type":"4"}},{"id":1227294,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-03-04T21:05:12.000Z","date":"2025-02-28","kind":"purchase","planned":false,"acquired":true,"shares":147649,"price":2.988,"value":441175.212,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $2.8256 - $3.345 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F4","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":8852649,"source":{"system":"sec-edgar","filing":"0001493152-25-009039","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225009039/ownership.xml","form_type":"4"}},{"id":1271273,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-02-13T00:42:21.000Z","date":"2025-02-12","kind":"purchase","planned":false,"acquired":true,"shares":15000,"price":3.9955,"value":59932.5,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F4","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $3.9868 - $4.045 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":8705000,"source":{"system":"sec-edgar","filing":"0001493152-25-006196","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":3,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225006196/ownership.xml","form_type":"4"}},{"id":1271272,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-02-13T00:42:21.000Z","date":"2025-02-11","kind":"purchase","planned":false,"acquired":true,"shares":12500,"price":4.112,"value":51400.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F3","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $4.0767 - $4.16 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":8690000,"source":{"system":"sec-edgar","filing":"0001493152-25-006196","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225006196/ownership.xml","form_type":"4"}},{"id":1271271,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":1559,"kind":"organization","name":"Opaleye Management Inc.","position":1,"cik":"0001595855","reported_name":"Opaleye Management Inc.","relationship":{"director":false,"officer":false,"ten_percent_owner":true,"other":false}}],"security":"Common Stock, par value $0.001 per share","published_at":"2025-02-13T00:42:21.000Z","date":"2025-02-10","kind":"purchase","planned":false,"acquired":true,"shares":22500,"price":4.1844,"value":94149.0,"ownership":{"direct":false,"nature":"By Opaleye, L.P."},"footnotes":[{"field":"price","element":"transactionPricePerShare","label":"F2","text":"The price reported in column 4 is a weighted average price. These shares were purchased in multiple transactions at prices ranging from $4.155 - $4.2095 inclusive. The reporting person undertakes to provide, upon request by the SEC staff, the issuer, or a security holder of the issuer, full information regarding the number of shares sold at each price."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F1","text":"Represents securities owned directly by Opaleye, L.P. (the \"Fund\"). As the investment manager of the Fund, Opaleye Management Inc. may be deemed to beneficially own the securities owned directly by the Fund."},{"field":"ownership.nature","element":"natureOfOwnership","label":"F5","text":"Opaleye Management Inc. disclaims beneficial ownership of the shares reported herein except to the extent of its pecuniary interest therein, and the filing of this Form 4 shall not be construed as an admission that Opaleye Management Inc. is the beneficial owner of any such shares for purposes of Section 16(a) of the Securities Exchange Act of 1934, as amended, or for any other purpose."}],"balance_after":8677500,"source":{"system":"sec-edgar","filing":"0001493152-25-006196","document":"ownership.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000149315225006196/ownership.xml","form_type":"4"}},{"id":1278548,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":46437,"kind":"person","name":"Norrett Kevin","position":1,"cik":"0001819690","reported_name":"Norrett Kevin","relationship":{"officer":true,"officer_title":"Chief Operating Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-02-08T01:20:55.000Z","date":"2025-02-05","kind":"grant","planned":false,"acquired":true,"shares":161250,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This option vests and becomes exercisable with respect to 25% of the shares subject thereto on the first anniversary of the grant date, and with respect to 1/48th of the original number of shares subject thereto on each monthly anniversary thereafter, subject to the Reporting Person's continued employment through the applicable vesting dates."}],"balance_after":161250,"derivative":{"exercise_price":4.37,"expiration_date":"2035-02-05","underlying":"Common Stock","underlying_shares":161250},"source":{"system":"sec-edgar","filing":"0000905148-25-000444","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000090514825000444/form4.xml","form_type":"4"}},{"id":1278547,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":46437,"kind":"person","name":"Norrett Kevin","position":1,"cik":"0001819690","reported_name":"Norrett Kevin","relationship":{"officer":true,"officer_title":"Chief Operating Officer"}}],"security":"Common Stock","published_at":"2025-02-08T01:20:55.000Z","date":"2025-02-05","kind":"grant","planned":false,"acquired":true,"shares":26875,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"These restricted stock units vest as to 1/3rd of the shares on each annual anniversary of the grant date, subject to the Reporting Person's continued employment through the applicable vesting dates."}],"balance_after":177327,"source":{"system":"sec-edgar","filing":"0000905148-25-000444","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000090514825000444/form4.xml","form_type":"4"}},{"id":1278546,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64703,"kind":"person","name":"MOORE ALISON","position":1,"cik":"0001754937","reported_name":"MOORE ALISON","relationship":{"officer":true,"officer_title":"Chief Technical Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-02-08T01:18:24.000Z","date":"2025-02-05","kind":"grant","planned":false,"acquired":true,"shares":161250,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This option vests and becomes exercisable with respect to 25% of the shares subject thereto on the first anniversary of the grant date, and with respect to 1/48th of the original number of shares subject thereto on each monthly anniversary thereafter, subject to the Reporting Person's continued employment through the applicable vesting dates."}],"balance_after":161250,"derivative":{"exercise_price":4.37,"expiration_date":"2035-02-05","underlying":"Common Stock","underlying_shares":161250},"source":{"system":"sec-edgar","filing":"0000905148-25-000442","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000090514825000442/form4.xml","form_type":"4"}},{"id":1278545,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64703,"kind":"person","name":"MOORE ALISON","position":1,"cik":"0001754937","reported_name":"MOORE ALISON","relationship":{"officer":true,"officer_title":"Chief Technical Officer"}}],"security":"Common Stock","published_at":"2025-02-08T01:18:24.000Z","date":"2025-02-05","kind":"grant","planned":false,"acquired":true,"shares":26875,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"These restricted stock units vest as to 1/3rd of the shares on each annual anniversary of the grant date, subject to the Reporting Person's continued employment through the applicable vesting dates."}],"balance_after":175571,"source":{"system":"sec-edgar","filing":"0000905148-25-000442","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000090514825000442/form4.xml","form_type":"4"}},{"id":1278544,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64702,"kind":"person","name":"Erbez Georgia","position":1,"cik":"0001557930","reported_name":"Erbez Georgia","relationship":{"officer":true,"officer_title":"Chief Financial Officer"}}],"security":"Stock Option (Right to Buy)","published_at":"2025-02-08T01:17:12.000Z","date":"2025-02-05","kind":"grant","planned":false,"acquired":true,"shares":161250,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"derivative.exercise_date","element":"exerciseDate","label":"F2","text":"This option vests and becomes exercisable with respect to 25% of the shares subject thereto on the first anniversary of the grant date, and with respect to 1/48th of the original number of shares subject thereto on each monthly anniversary thereafter, subject to the Reporting Person's continued employment through the applicable vesting dates."}],"balance_after":161250,"derivative":{"exercise_price":4.37,"expiration_date":"2035-02-05","underlying":"Common Stock","underlying_shares":161250},"source":{"system":"sec-edgar","filing":"0000905148-25-000440","document":"form4.xml","document_sequence":1,"table":"derivative","row_type":"transaction","position":2,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000090514825000440/form4.xml","form_type":"4"}},{"id":1278543,"issuer":{"id":6428,"kind":"organization","name":"CODEXIS, INC.","symbol":"CDXS"},"owners":[{"id":64702,"kind":"person","name":"Erbez Georgia","position":1,"cik":"0001557930","reported_name":"Erbez Georgia","relationship":{"officer":true,"officer_title":"Chief Financial Officer"}}],"security":"Common Stock","published_at":"2025-02-08T01:17:12.000Z","date":"2025-02-05","kind":"grant","planned":false,"acquired":true,"shares":26875,"price":0,"value":0.0,"ownership":{"direct":true},"footnotes":[{"field":"shares","element":"transactionShares","label":"F1","text":"These restricted stock units vest as to 1/3rd of the shares on each annual anniversary of the grant date, subject to the Reporting Person's continued employment through the applicable vesting dates."}],"balance_after":76875,"source":{"system":"sec-edgar","filing":"0000905148-25-000440","document":"form4.xml","document_sequence":1,"table":"nonDerivative","row_type":"transaction","position":1,"url":"https://www.sec.gov/Archives/edgar/data/1200375/000090514825000440/form4.xml","form_type":"4"}}],"next_cursor":"2025-02-08T01:17:12.000000Z,1278543"}